4NWJ | Genus

Total Genus 189

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	189
Knots found	KnotProt 2.0: S +3₁
sequence length	504
structure length	504
Chain Sequence	AKKPTALIILDGFANRESEHGNAVKLANKPNFDRYYNKYPTTQIEASGLDVGLPEGQMGNSEVGHMNIGAGRIVYQSLTRINKSIEDGDFFENDVLNNAIAHVNSHDSALHIFGLLSDGGVHSHYKHLFALLELAKKQGVEKVYVHAFLDGRDVDQKSALKYIEETEAKFNELGIGQFASVSGRYYAMDRDKRWEREEKAYNAIRNFDAPTYATAKEGVEASYNEGLTDEFVVPFIVENQNDGVNDGDAVIFYNFRPDRAAQLSEIFANRAFEGFKVEQVKDLFYATFTKYNDNIDAAIVFEKVDLNNTIGEIAQNNNLTQLRIAETEKYPHVTYFMSGGRNEEFKGERRRLIDSPKVATYDLKPEMSAYEVKDALLEELNKGDLDLIILNFANPDMVGHSGMLEPTIKAIEAVDECLGEVVDKILDMDGYAIITADHGNSDQVLTDDDQPMTTHTTNPVPVIVTKEGVTLRETGRLGDLAPTLLDLLNVEQPEDMTGESLIKH

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Complete catalytic cycle of cofactor-independent phosphoglycerate mutase involves a spring-loaded mechanism pubmed doi rcsb
molecule keywords	2,3-bisphosphoglycerate-independent phosphoglycerate mutase
molecule tags	Isomerase
source organism	Staphylococcus aureus subsp. aureus
total genus	189
structure length	504
sequence length	504
other databases	KnotProt 2.0: S +3₁
ec nomenclature	ec 5.4.2.12: Phosphoglycerate mutase (2,3-diphosphoglycerate-independent).
pdb deposition date	2013-12-06

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01676	Metalloenzyme	Metalloenzyme superfamily
A	PF06415	iPGM_N	BPG-independent PGAM N-terminus (iPGM_N)

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.720.10	Alpha Beta	3-Layer(aba) Sandwich	Alkaline Phosphatase, subunit A	Alkaline Phosphatase, subunit A	4nwjA01
3.40.1450.10	Alpha Beta	3-Layer(aba) Sandwich	2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain	BPG-independent phosphoglycerate mutase, domain B	4nwjA02

3M8WA 1AJBA 3IGYB 2W5RA 5LRMA 1URAA 2XR9A 3DYCA 1ELYA 3DPCA 4LRAA 2IUCA 2RH6A 2ANHA 3TX0A 3WBHA 3TG0A 1ED8A 3WAXA 3UN2A 4GTWA 1HDHA 2XRGA 1ED9A 3Q3QA 2W8DA 5GRRA 4LRDA 1KHJA 3WAVA 1B8JA 1EW2A 3ED4A 4GTZA 1HJKA 2W5QA 5LQQA 4FDIA 4UPIA 2IFYA 5GOVA 3LXQA 1AUKA 3TWZA 1ELXA 3SZYA 3WAWA 1O98A 3WAYA 1SHQA 4LR7A 1E33P 1ZEDA 4YR1A 3BDGA 2G9YA 1KHNA 3OT9A 2D1GA 4UPKA 5L0EA 1ALJA 3UO0A 1AJAA 1KH4A 1EW9A 3T02A 4CXUA 4CYSA 1O99A 1KH5A 4B56A 1ZEFA 3NKMA 1ALKA 4KJDA 5TJ3A 3B5QA 4KAVA 5IJQA 2X98A 3A52A 3MK1A 5LIAA 2GLQA 3BDGB 1KH7A 1HQAA 3NKRA 4GTXA 4CXSA 1Y7AA 3T00A 4UORA 4NWJA 3NKNA 1ELZA 2QZUA 2W5XA 5K4PA 1ALIA 2W5SA 3M7VA 1EJJA 2ZKTA 4LR8A 4UPLA 5HRTA 3UNYA 4QAXA 2GSOA 4NWXA 3KD8A 3MK0A 1AJDA 4ZG9A 2GA3A 3IDDA 4LR9A 2GSNA 1E2SP 3UN5A 5KXAA 1EQJA 4TN0A 4N7TA 3M8YA 2W5VA 1EI6A 1N2KA 3T01A 5IJSA 1URBA 5DLWA 3NKQA 2W5TA 3NVLA 1ALHA 4FDJA 4LREA 4MIVA 4UPHA 5DLVA 1P49A 5EGEA 3SZZA 5LRNA 4GTYA 3IGZB 1KH9A 1FSUA 4CYRA 3CMRA 5INHA 4ZG7A 4LQYA 1ANIA 1N2LA 1Y6VA 5C66A 1E3CP 1K7HA 4KM4A 4LRCA 4KAYA 4ZGAA 4CXKA 1ANJA 5EGHA 3MK2A 2W8SA 4KJGA 3UN3A 4MY4A 4UOPA 3BDHA 3NKOA 2VQRA 2IUCB 1KHKA 4LRBA 1ZEBA 3BDFA 1E1ZP 2GSUA 4UOOA 1KHLA 1SHNA 3M8ZA 5DLTA 5AJ9A 4LR2A 1AJCA 3NKPA 4MHXA 4LRFA 5L0KA 4ZG6A 3E2DA 2W5WA 1EW8A 5L0BA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 3M8W A;  1AJB A;  3IGY B;  2W5R A;  5LRM A;  1URA A;  2XR9 A;  3DYC A;  1ELY A;  3DPC A;  4LRA A;  2IUC A;  2RH6 A;  2ANH A;  3TX0 A;  3WBH A;  3TG0 A;  1ED8 A;  3WAX A;  3UN2 A;  4GTW A;  1HDH A;  2XRG A;  1ED9 A;  3Q3Q A;  2W8D A;  5GRR A;  4LRD A;  1KHJ A;  3WAV A;  1B8J A;  1EW2 A;  3ED4 A;  4GTZ A;  1HJK A;  2W5Q A;  5LQQ A;  4FDI A;  4UPI A;  2IFY A;  5GOV A;  3LXQ A;  1AUK A;  3TWZ A;  1ELX A;  3SZY A;  3WAW A;  1O98 A;  3WAY A;  1SHQ A;  4LR7 A;  1E33 P;  1ZED A;  4YR1 A;  3BDG A;  2G9Y A;  1KHN A;  3OT9 A;  2D1G A;  4UPK A;  5L0E A;  1ALJ A;  3UO0 A;  1AJA A;  1KH4 A;  1EW9 A;  3T02 A;  4CXU A;  4CYS A;  1O99 A;  1KH5 A;  4B56 A;  1ZEF A;  3NKM A;  1ALK A;  4KJD A;  5TJ3 A;  3B5Q A;  4KAV A;  5IJQ A;  2X98 A;  3A52 A;  3MK1 A;  5LIA A;  2GLQ A;  3BDG B;  1KH7 A;  1HQA A;  3NKR A;  4GTX A;  4CXS A;  1Y7A A;  3T00 A;  4UOR A;  4NWJ A;  3NKN A;  1ELZ A;  2QZU A;  2W5X A;  5K4P A;  1ALI A;  2W5S A;  3M7V A;  1EJJ A;  2ZKT A;  4LR8 A;  4UPL A;  5HRT A;  3UNY A;  4QAX A;  2GSO A;  4NWX A;  3KD8 A;  3MK0 A;  1AJD A;  4ZG9 A;  2GA3 A;  3IDD A;  4LR9 A;  2GSN A;  1E2S P;  3UN5 A;  5KXA A;  1EQJ A;  4TN0 A;  4N7T A;  3M8Y A;  2W5V A;  1EI6 A;  1N2K A;  3T01 A;  5IJS A;  1URB A;  5DLW A;  3NKQ A;  2W5T A;  3NVL A;  1ALH A;  4FDJ A;  4LRE A;  4MIV A;  4UPH A;  5DLV A;  1P49 A;  5EGE A;  3SZZ A;  5LRN A;  4GTY A;  3IGZ B;  1KH9 A;  1FSU A;  4CYR A;  3CMR A;  5INH A;  4ZG7 A;  4LQY A;  1ANI A;  1N2L A;  1Y6V A;  5C66 A;  1E3C P;  1K7H A;  4KM4 A;  4LRC A;  4KAY A;  4ZGA A;  4CXK A;  1ANJ A;  5EGH A;  3MK2 A;  2W8S A;  4KJG A;  3UN3 A;  4MY4 A;  4UOP A;  3BDH A;  3NKO A;  2VQR A;  2IUC B;  1KHK A;  4LRB A;  1ZEB A;  3BDF A;  1E1Z P;  2GSU A;  4UOO A;  1KHL A;  1SHN A;  3M8Z A;  5DLT A;  5AJ9 A;  4LR2 A;  1AJC A;  3NKP A;  4MHX A;  4LRF A;  5L0K A;  4ZG6 A;  3E2D A;  2W5W A;  1EW8 A;  5L0B A; 
#chains in the Genus database with same CATH topology
 3M8W A;  1AJB A;  3IGY B;  2W5R A;  5LRM A;  1URA A;  2XR9 A;  3DYC A;  1ELY A;  3DPC A;  4LRA A;  2IUC A;  2RH6 A;  2ANH A;  3TX0 A;  3WBH A;  3TG0 A;  1ED8 A;  3WAX A;  3UN2 A;  4GTW A;  1HDH A;  2XRG A;  1ED9 A;  3Q3Q A;  2W8D A;  5GRR A;  4LRD A;  1KHJ A;  3WAV A;  1B8J A;  1EW2 A;  3ED4 A;  4GTZ A;  1HJK A;  2W5Q A;  5LQQ A;  4FDI A;  4UPI A;  2IFY A;  5GOV A;  3LXQ A;  1AUK A;  3TWZ A;  1ELX A;  3SZY A;  3WAW A;  1O98 A;  3WAY A;  1SHQ A;  4LR7 A;  1E33 P;  1ZED A;  4YR1 A;  3BDG A;  2G9Y A;  1KHN A;  3OT9 A;  2D1G A;  4UPK A;  5L0E A;  1ALJ A;  3UO0 A;  1AJA A;  1KH4 A;  1EW9 A;  3T02 A;  4CXU A;  4CYS A;  1O99 A;  1KH5 A;  4B56 A;  1ZEF A;  3NKM A;  1ALK A;  4KJD A;  5TJ3 A;  3B5Q A;  4KAV A;  5IJQ A;  2X98 A;  3A52 A;  3MK1 A;  5LIA A;  2GLQ A;  3BDG B;  1KH7 A;  1HQA A;  3NKR A;  4GTX A;  4CXS A;  1Y7A A;  3T00 A;  4UOR A;  4NWJ A;  3NKN A;  1ELZ A;  2QZU A;  2W5X A;  5K4P A;  1ALI A;  2W5S A;  3M7V A;  1EJJ A;  2ZKT A;  4LR8 A;  4UPL A;  5HRT A;  3UNY A;  4QAX A;  2GSO A;  4NWX A;  3KD8 A;  3MK0 A;  1AJD A;  4ZG9 A;  2GA3 A;  3IDD A;  4LR9 A;  2GSN A;  1E2S P;  3UN5 A;  5KXA A;  1EQJ A;  4TN0 A;  4N7T A;  3M8Y A;  2W5V A;  1EI6 A;  1N2K A;  3T01 A;  5IJS A;  1URB A;  5DLW A;  3NKQ A;  2W5T A;  3NVL A;  1ALH A;  4FDJ A;  4LRE A;  4MIV A;  4UPH A;  5DLV A;  1P49 A;  5EGE A;  3SZZ A;  5LRN A;  4GTY A;  3IGZ B;  1KH9 A;  1FSU A;  4CYR A;  3CMR A;  5INH A;  4ZG7 A;  4LQY A;  1ANI A;  1N2L A;  1Y6V A;  5C66 A;  1E3C P;  1K7H A;  4KM4 A;  4LRC A;  4KAY A;  4ZGA A;  4CXK A;  1ANJ A;  5EGH A;  3MK2 A;  2W8S A;  4KJG A;  3UN3 A;  4MY4 A;  4UOP A;  3BDH A;  3NKO A;  2VQR A;  2IUC B;  1KHK A;  4LRB A;  1ZEB A;  3BDF A;  1E1Z P;  2GSU A;  4UOO A;  1KHL A;  1SHN A;  3M8Z A;  5DLT A;  5AJ9 A;  4LR2 A;  1AJC A;  3NKP A;  4MHX A;  4LRF A;  5L0K A;  4ZG6 A;  3E2D A;  2W5W A;  1EW8 A;  5L0B A; 
#chains in the Genus database with same CATH homology
 3M8W A;  1AJB A;  3IGY B;  2W5R A;  5LRM A;  1URA A;  2XR9 A;  3DYC A;  1ELY A;  3DPC A;  4LRA A;  2IUC A;  2RH6 A;  2ANH A;  3TX0 A;  3WBH A;  3TG0 A;  1ED8 A;  3WAX A;  3UN2 A;  4GTW A;  1HDH A;  2XRG A;  1ED9 A;  3Q3Q A;  2W8D A;  5GRR A;  4LRD A;  1KHJ A;  3WAV A;  1B8J A;  1EW2 A;  3ED4 A;  4GTZ A;  1HJK A;  2W5Q A;  5LQQ A;  4FDI A;  4UPI A;  2IFY A;  5GOV A;  3LXQ A;  1AUK A;  3TWZ A;  1ELX A;  3SZY A;  3WAW A;  1O98 A;  3WAY A;  1SHQ A;  4LR7 A;  1E33 P;  1ZED A;  4YR1 A;  3BDG A;  2G9Y A;  1KHN A;  3OT9 A;  2D1G A;  4UPK A;  5L0E A;  1ALJ A;  3UO0 A;  1AJA A;  1KH4 A;  1EW9 A;  3T02 A;  4CXU A;  4CYS A;  1O99 A;  1KH5 A;  4B56 A;  1ZEF A;  3NKM A;  1ALK A;  4KJD A;  5TJ3 A;  3B5Q A;  4KAV A;  5IJQ A;  2X98 A;  3A52 A;  3MK1 A;  5LIA A;  2GLQ A;  3BDG B;  1KH7 A;  1HQA A;  3NKR A;  4GTX A;  4CXS A;  1Y7A A;  3T00 A;  4UOR A;  4NWJ A;  3NKN A;  1ELZ A;  2QZU A;  2W5X A;  5K4P A;  1ALI A;  2W5S A;  3M7V A;  1EJJ A;  2ZKT A;  4LR8 A;  4UPL A;  5HRT A;  3UNY A;  4QAX A;  2GSO A;  4NWX A;  3KD8 A;  3MK0 A;  1AJD A;  4ZG9 A;  2GA3 A;  3IDD A;  4LR9 A;  2GSN A;  1E2S P;  3UN5 A;  5KXA A;  1EQJ A;  4TN0 A;  4N7T A;  3M8Y A;  2W5V A;  1EI6 A;  1N2K A;  3T01 A;  5IJS A;  1URB A;  5DLW A;  3NKQ A;  2W5T A;  3NVL A;  1ALH A;  4FDJ A;  4LRE A;  4MIV A;  4UPH A;  5DLV A;  1P49 A;  5EGE A;  3SZZ A;  5LRN A;  4GTY A;  3IGZ B;  1KH9 A;  1FSU A;  4CYR A;  3CMR A;  5INH A;  4ZG7 A;  4LQY A;  1ANI A;  1N2L A;  1Y6V A;  5C66 A;  1E3C P;  1K7H A;  4KM4 A;  4LRC A;  4KAY A;  4ZGA A;  4CXK A;  1ANJ A;  5EGH A;  3MK2 A;  2W8S A;  4KJG A;  3UN3 A;  4MY4 A;  4UOP A;  3BDH A;  3NKO A;  2VQR A;  2IUC B;  1KHK A;  4LRB A;  1ZEB A;  3BDF A;  1E1Z P;  2GSU A;  4UOO A;  1KHL A;  1SHN A;  3M8Z A;  5DLT A;  5AJ9 A;  4LR2 A;  1AJC A;  3NKP A;  4MHX A;  4LRF A;  5L0K A;  4ZG6 A;  3E2D A;  2W5W A;  1EW8 A;  5L0B A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4NWJA

Total Genus

Knots found

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations