5GRRA

Crystal structure of mcr-1
Total Genus 128
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
128
Knots found
sequence length
323
structure length
323
Chain Sequence
TIYHAKDAVQATKPDMRKPRLVVFVVGETARADHVSFNGYERDTFPQLAKIDGVTNFSNVTSCGTSTAYSVPCMFSYLGADEYDVDTAKYQENVLDTLDRLGVSILWRDNNSDSKGVMDKLPKAQFADYKSATNNAICNTNPYNECRDVGMLVGLDDFVAANNGKDMLIMLHQMGNHGPAYFKRYDEKFAKFTPVCEGNELAKCEHQSLINAYDNALLATDDFIAQSIQWLQTHSNAYDVSMLYVSDHGESLGENGVYLHGMPNAFAPKEQRSVPAFFWTDKQTGITPMATDTVLTHDAITPTLLKLFDVTADKVKDRTAFIR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title High resolution crystal structure of the catalytic domain of MCR-1
pubmed doi rcsb
molecule tags Transferase
source organism Escherichia coli
molecule keywords Probable phosphatidylethanolamine transferase Mcr-1
total genus 128
structure length 323
sequence length 323
other databases KnotProt 2.0: S +31
ec nomenclature ec 2.7.-.-:
pdb deposition date 2016-08-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00884 Sulfatase Sulfatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 5grrA00
1SHQA 2RH6A 1URAA 1O99A 2GLQA 2XR9A 3IGYB 4LR7A 4LQYA 4LR9A 4NWXA 4LRBA 4UPKA 5LIAA 1KH7A 1E3CP 4GTYA 2ZKTA 4UPHA 2W5TA 4B56A 3M7VA 2IFYA 3TWZA 3A52A 4LREA 3BDFA 5KXAA 2QZUA 4FDIA 4MIVA 1AJDA 3NKOA 2GSOA 2VQRA 1E33P 1KHNA 1KHKA 2G9YA 5L0KA 2X98A 1AUKA 1KH4A 2IUCA 1KHLA 1EQJA 1ELYA 4MHXA 3WBHA 1Y6VA 5EGHA 5EGEA 1AJCA 2ANHA 4ZG9A 4N7TA 3MK2A 2XRGA 4LRFA 1URBA 1AJBA 2W5QA 1N2LA 3KD8A 3WAWA 5GRRA 3B5QA 1EW8A 4KJDA 5DLWA 5TJ3A 4KAVA 1HQAA 2W8DA 4CYRA 1K7HA 5DLVA 4CXKA 4UPLA 4ZG6A 1ANJA 4GTWA 3NKNA 4UORA 3NKRA 4UOPA 2W5SA 1O98A 1ALKA 2D1GA 3M8WA 1ED9A 1ZEDA 4ZGAA 3NKQA 5HRTA 1ALIA 5IJQA 1E1ZP 4QAXA 3UN3A 4ZG7A 5LRNA 5LQQA 3E2DA 1EI6A 3UN5A 4CYSA 3T01A 3WAVA 3UNYA 1FSUA 4KAYA 3Q3QA 1HJKA 4LRAA 5L0EA 2GA3A 2W5WA 5GOVA 1ANIA 4TN0A 1AJAA 5K4PA 3ED4A 2GSUA 3MK0A 3LXQA 3NKPA 4FDJA 5AJ9A 1EW9A 4UPIA 3WAYA 5LRMA 1ALJA 3DPCA 4CXSA 3UO0A 1EW2A 3IGZB 1N2KA 3TG0A 4GTXA 3WAXA 4LRCA 2W5XA 3IDDA 5DLTA 3TX0A 5L0BA 1Y7AA 3BDGB 3SZZA 1ALHA 4UOOA 3UN2A 1KHJA 1ELZA 3M8ZA 3M8YA 2W5RA 5IJSA 4KJGA 2W5VA 4KM4A 1EJJA 1ELXA 3NKMA 1P49A 3T02A 2W8SA 1ZEFA 4MY4A 4LR2A 3CMRA 4LRDA 3BDHA 3BDGA 4LR8A 3SZYA 3DYCA 4CXUA 3OT9A 4YR1A 1KH5A 4GTZA 1SHNA 1ED8A 2GSNA 4NWJA 3T00A 1HDHA 1KH9A 5INHA 3NVLA 5C66A 2IUCB 3MK1A 1E2SP 1ZEBA 1B8JA
chains in the Genus database with same CATH superfamily
1SHQA 2RH6A 1URAA 1O99A 2GLQA 2XR9A 3IGYB 4LR7A 4LQYA 4LR9A 4NWXA 4LRBA 4UPKA 5LIAA 1KH7A 1E3CP 4GTYA 2ZKTA 4UPHA 2W5TA 4B56A 3M7VA 2IFYA 3TWZA 3A52A 4LREA 3BDFA 5KXAA 2QZUA 4FDIA 4MIVA 1AJDA 3NKOA 2GSOA 2VQRA 1E33P 1KHNA 1KHKA 2G9YA 5L0KA 2X98A 1AUKA 1KH4A 2IUCA 1KHLA 1EQJA 1ELYA 4MHXA 3WBHA 1Y6VA 5EGHA 5EGEA 1AJCA 2ANHA 4ZG9A 4N7TA 3MK2A 2XRGA 4LRFA 1URBA 1AJBA 2W5QA 1N2LA 3KD8A 3WAWA 5GRRA 3B5QA 1EW8A 4KJDA 5DLWA 5TJ3A 4KAVA 1HQAA 2W8DA 4CYRA 1K7HA 5DLVA 4CXKA 4UPLA 4ZG6A 1ANJA 4GTWA 3NKNA 4UORA 3NKRA 4UOPA 2W5SA 1O98A 1ALKA 2D1GA 3M8WA 1ED9A 1ZEDA 4ZGAA 3NKQA 5HRTA 1ALIA 5IJQA 1E1ZP 4QAXA 3UN3A 4ZG7A 5LRNA 5LQQA 3E2DA 1EI6A 3UN5A 4CYSA 3T01A 3WAVA 3UNYA 1FSUA 4KAYA 3Q3QA 1HJKA 4LRAA 5L0EA 2GA3A 2W5WA 5GOVA 1ANIA 4TN0A 1AJAA 5K4PA 3ED4A 2GSUA 3MK0A 3LXQA 3NKPA 4FDJA 5AJ9A 1EW9A 4UPIA 3WAYA 5LRMA 1ALJA 3DPCA 4CXSA 3UO0A 1EW2A 3IGZB 1N2KA 3TG0A 4GTXA 3WAXA 4LRCA 2W5XA 3IDDA 5DLTA 3TX0A 5L0BA 1Y7AA 3BDGB 3SZZA 1ALHA 4UOOA 3UN2A 1KHJA 1ELZA 3M8ZA 3M8YA 2W5RA 5IJSA 4KJGA 2W5VA 4KM4A 1EJJA 1ELXA 3NKMA 1P49A 3T02A 2W8SA 1ZEFA 4MY4A 4LR2A 3CMRA 4LRDA 3BDHA 3BDGA 4LR8A 3SZYA 3DYCA 4CXUA 3OT9A 4YR1A 1KH5A 4GTZA 1SHNA 1ED8A 2GSNA 4NWJA 3T00A 1HDHA 1KH9A 5INHA 3NVLA 5C66A 2IUCB 3MK1A 1E2SP 1ZEBA 1B8JA
chains in the Genus database with same CATH topology
1SHQA 2RH6A 1URAA 1O99A 2GLQA 2XR9A 3IGYB 4LR7A 4LQYA 4LR9A 4NWXA 4LRBA 4UPKA 5LIAA 1KH7A 1E3CP 4GTYA 2ZKTA 4UPHA 2W5TA 4B56A 3M7VA 2IFYA 3TWZA 3A52A 4LREA 3BDFA 5KXAA 2QZUA 4FDIA 4MIVA 1AJDA 3NKOA 2GSOA 2VQRA 1E33P 1KHNA 1KHKA 2G9YA 5L0KA 2X98A 1AUKA 1KH4A 2IUCA 1KHLA 1EQJA 1ELYA 4MHXA 3WBHA 1Y6VA 5EGHA 5EGEA 1AJCA 2ANHA 4ZG9A 4N7TA 3MK2A 2XRGA 4LRFA 1URBA 1AJBA 2W5QA 1N2LA 3KD8A 3WAWA 5GRRA 3B5QA 1EW8A 4KJDA 5DLWA 5TJ3A 4KAVA 1HQAA 2W8DA 4CYRA 1K7HA 5DLVA 4CXKA 4UPLA 4ZG6A 1ANJA 4GTWA 3NKNA 4UORA 3NKRA 4UOPA 2W5SA 1O98A 1ALKA 2D1GA 3M8WA 1ED9A 1ZEDA 4ZGAA 3NKQA 5HRTA 1ALIA 5IJQA 1E1ZP 4QAXA 3UN3A 4ZG7A 5LRNA 5LQQA 3E2DA 1EI6A 3UN5A 4CYSA 3T01A 3WAVA 3UNYA 1FSUA 4KAYA 3Q3QA 1HJKA 4LRAA 5L0EA 2GA3A 2W5WA 5GOVA 1ANIA 4TN0A 1AJAA 5K4PA 3ED4A 2GSUA 3MK0A 3LXQA 3NKPA 4FDJA 5AJ9A 1EW9A 4UPIA 3WAYA 5LRMA 1ALJA 3DPCA 4CXSA 3UO0A 1EW2A 3IGZB 1N2KA 3TG0A 4GTXA 3WAXA 4LRCA 2W5XA 3IDDA 5DLTA 3TX0A 5L0BA 1Y7AA 3BDGB 3SZZA 1ALHA 4UOOA 3UN2A 1KHJA 1ELZA 3M8ZA 3M8YA 2W5RA 5IJSA 4KJGA 2W5VA 4KM4A 1EJJA 1ELXA 3NKMA 1P49A 3T02A 2W8SA 1ZEFA 4MY4A 4LR2A 3CMRA 4LRDA 3BDHA 3BDGA 4LR8A 3SZYA 3DYCA 4CXUA 3OT9A 4YR1A 1KH5A 4GTZA 1SHNA 1ED8A 2GSNA 4NWJA 3T00A 1HDHA 1KH9A 5INHA 3NVLA 5C66A 2IUCB 3MK1A 1E2SP 1ZEBA 1B8JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SHQ A;  2RH6 A;  1URA A;  1O99 A;  2GLQ A;  2XR9 A;  3IGY B;  4LR7 A;  4LQY A;  4LR9 A;  4NWX A;  4LRB A;  4UPK A;  5LIA A;  1KH7 A;  1E3C P;  4GTY A;  2ZKT A;  4UPH A;  2W5T A;  4B56 A;  3M7V A;  2IFY A;  3TWZ A;  3A52 A;  4LRE A;  3BDF A;  5KXA A;  2QZU A;  4FDI A;  4MIV A;  1AJD A;  3NKO A;  2GSO A;  2VQR A;  1E33 P;  1KHN A;  1KHK A;  2G9Y A;  5L0K A;  2X98 A;  1AUK A;  1KH4 A;  2IUC A;  1KHL A;  1EQJ A;  1ELY A;  4MHX A;  3WBH A;  1Y6V A;  5EGH A;  5EGE A;  1AJC A;  2ANH A;  4ZG9 A;  4N7T A;  3MK2 A;  2XRG A;  4LRF A;  1URB A;  1AJB A;  2W5Q A;  1N2L A;  3KD8 A;  3WAW A;  5GRR A;  3B5Q A;  1EW8 A;  4KJD A;  5DLW A;  5TJ3 A;  4KAV A;  1HQA A;  2W8D A;  4CYR A;  1K7H A;  5DLV A;  4CXK A;  4UPL A;  4ZG6 A;  1ANJ A;  4GTW A;  3NKN A;  4UOR A;  3NKR A;  4UOP A;  2W5S A;  1O98 A;  1ALK A;  2D1G A;  3M8W A;  1ED9 A;  1ZED A;  4ZGA A;  3NKQ A;  5HRT A;  1ALI A;  5IJQ A;  1E1Z P;  4QAX A;  3UN3 A;  4ZG7 A;  5LRN A;  5LQQ A;  3E2D A;  1EI6 A;  3UN5 A;  4CYS A;  3T01 A;  3WAV A;  3UNY A;  1FSU A;  4KAY A;  3Q3Q A;  1HJK A;  4LRA A;  5L0E A;  2GA3 A;  2W5W A;  5GOV A;  1ANI A;  4TN0 A;  1AJA A;  5K4P A;  3ED4 A;  2GSU A;  3MK0 A;  3LXQ A;  3NKP A;  4FDJ A;  5AJ9 A;  1EW9 A;  4UPI A;  3WAY A;  5LRM A;  1ALJ A;  3DPC A;  4CXS A;  3UO0 A;  1EW2 A;  3IGZ B;  1N2K A;  3TG0 A;  4GTX A;  3WAX A;  4LRC A;  2W5X A;  3IDD A;  5DLT A;  3TX0 A;  5L0B A;  1Y7A A;  3BDG B;  3SZZ A;  1ALH A;  4UOO A;  3UN2 A;  1KHJ A;  1ELZ A;  3M8Z A;  3M8Y A;  2W5R A;  5IJS A;  4KJG A;  2W5V A;  4KM4 A;  1EJJ A;  1ELX A;  3NKM A;  1P49 A;  3T02 A;  2W8S A;  1ZEF A;  4MY4 A;  4LR2 A;  3CMR A;  4LRD A;  3BDH A;  3BDG A;  4LR8 A;  3SZY A;  3DYC A;  4CXU A;  3OT9 A;  4YR1 A;  1KH5 A;  4GTZ A;  1SHN A;  1ED8 A;  2GSN A;  4NWJ A;  3T00 A;  1HDH A;  1KH9 A;  5INH A;  3NVL A;  5C66 A;  2IUC B;  3MK1 A;  1E2S P;  1ZEB A;  1B8J A; 
#chains in the Genus database with same CATH topology
 1SHQ A;  2RH6 A;  1URA A;  1O99 A;  2GLQ A;  2XR9 A;  3IGY B;  4LR7 A;  4LQY A;  4LR9 A;  4NWX A;  4LRB A;  4UPK A;  5LIA A;  1KH7 A;  1E3C P;  4GTY A;  2ZKT A;  4UPH A;  2W5T A;  4B56 A;  3M7V A;  2IFY A;  3TWZ A;  3A52 A;  4LRE A;  3BDF A;  5KXA A;  2QZU A;  4FDI A;  4MIV A;  1AJD A;  3NKO A;  2GSO A;  2VQR A;  1E33 P;  1KHN A;  1KHK A;  2G9Y A;  5L0K A;  2X98 A;  1AUK A;  1KH4 A;  2IUC A;  1KHL A;  1EQJ A;  1ELY A;  4MHX A;  3WBH A;  1Y6V A;  5EGH A;  5EGE A;  1AJC A;  2ANH A;  4ZG9 A;  4N7T A;  3MK2 A;  2XRG A;  4LRF A;  1URB A;  1AJB A;  2W5Q A;  1N2L A;  3KD8 A;  3WAW A;  5GRR A;  3B5Q A;  1EW8 A;  4KJD A;  5DLW A;  5TJ3 A;  4KAV A;  1HQA A;  2W8D A;  4CYR A;  1K7H A;  5DLV A;  4CXK A;  4UPL A;  4ZG6 A;  1ANJ A;  4GTW A;  3NKN A;  4UOR A;  3NKR A;  4UOP A;  2W5S A;  1O98 A;  1ALK A;  2D1G A;  3M8W A;  1ED9 A;  1ZED A;  4ZGA A;  3NKQ A;  5HRT A;  1ALI A;  5IJQ A;  1E1Z P;  4QAX A;  3UN3 A;  4ZG7 A;  5LRN A;  5LQQ A;  3E2D A;  1EI6 A;  3UN5 A;  4CYS A;  3T01 A;  3WAV A;  3UNY A;  1FSU A;  4KAY A;  3Q3Q A;  1HJK A;  4LRA A;  5L0E A;  2GA3 A;  2W5W A;  5GOV A;  1ANI A;  4TN0 A;  1AJA A;  5K4P A;  3ED4 A;  2GSU A;  3MK0 A;  3LXQ A;  3NKP A;  4FDJ A;  5AJ9 A;  1EW9 A;  4UPI A;  3WAY A;  5LRM A;  1ALJ A;  3DPC A;  4CXS A;  3UO0 A;  1EW2 A;  3IGZ B;  1N2K A;  3TG0 A;  4GTX A;  3WAX A;  4LRC A;  2W5X A;  3IDD A;  5DLT A;  3TX0 A;  5L0B A;  1Y7A A;  3BDG B;  3SZZ A;  1ALH A;  4UOO A;  3UN2 A;  1KHJ A;  1ELZ A;  3M8Z A;  3M8Y A;  2W5R A;  5IJS A;  4KJG A;  2W5V A;  4KM4 A;  1EJJ A;  1ELX A;  3NKM A;  1P49 A;  3T02 A;  2W8S A;  1ZEF A;  4MY4 A;  4LR2 A;  3CMR A;  4LRD A;  3BDH A;  3BDG A;  4LR8 A;  3SZY A;  3DYC A;  4CXU A;  3OT9 A;  4YR1 A;  1KH5 A;  4GTZ A;  1SHN A;  1ED8 A;  2GSN A;  4NWJ A;  3T00 A;  1HDH A;  1KH9 A;  5INH A;  3NVL A;  5C66 A;  2IUC B;  3MK1 A;  1E2S P;  1ZEB A;  1B8J A; 
#chains in the Genus database with same CATH homology
 1SHQ A;  2RH6 A;  1URA A;  1O99 A;  2GLQ A;  2XR9 A;  3IGY B;  4LR7 A;  4LQY A;  4LR9 A;  4NWX A;  4LRB A;  4UPK A;  5LIA A;  1KH7 A;  1E3C P;  4GTY A;  2ZKT A;  4UPH A;  2W5T A;  4B56 A;  3M7V A;  2IFY A;  3TWZ A;  3A52 A;  4LRE A;  3BDF A;  5KXA A;  2QZU A;  4FDI A;  4MIV A;  1AJD A;  3NKO A;  2GSO A;  2VQR A;  1E33 P;  1KHN A;  1KHK A;  2G9Y A;  5L0K A;  2X98 A;  1AUK A;  1KH4 A;  2IUC A;  1KHL A;  1EQJ A;  1ELY A;  4MHX A;  3WBH A;  1Y6V A;  5EGH A;  5EGE A;  1AJC A;  2ANH A;  4ZG9 A;  4N7T A;  3MK2 A;  2XRG A;  4LRF A;  1URB A;  1AJB A;  2W5Q A;  1N2L A;  3KD8 A;  3WAW A;  5GRR A;  3B5Q A;  1EW8 A;  4KJD A;  5DLW A;  5TJ3 A;  4KAV A;  1HQA A;  2W8D A;  4CYR A;  1K7H A;  5DLV A;  4CXK A;  4UPL A;  4ZG6 A;  1ANJ A;  4GTW A;  3NKN A;  4UOR A;  3NKR A;  4UOP A;  2W5S A;  1O98 A;  1ALK A;  2D1G A;  3M8W A;  1ED9 A;  1ZED A;  4ZGA A;  3NKQ A;  5HRT A;  1ALI A;  5IJQ A;  1E1Z P;  4QAX A;  3UN3 A;  4ZG7 A;  5LRN A;  5LQQ A;  3E2D A;  1EI6 A;  3UN5 A;  4CYS A;  3T01 A;  3WAV A;  3UNY A;  1FSU A;  4KAY A;  3Q3Q A;  1HJK A;  4LRA A;  5L0E A;  2GA3 A;  2W5W A;  5GOV A;  1ANI A;  4TN0 A;  1AJA A;  5K4P A;  3ED4 A;  2GSU A;  3MK0 A;  3LXQ A;  3NKP A;  4FDJ A;  5AJ9 A;  1EW9 A;  4UPI A;  3WAY A;  5LRM A;  1ALJ A;  3DPC A;  4CXS A;  3UO0 A;  1EW2 A;  3IGZ B;  1N2K A;  3TG0 A;  4GTX A;  3WAX A;  4LRC A;  2W5X A;  3IDD A;  5DLT A;  3TX0 A;  5L0B A;  1Y7A A;  3BDG B;  3SZZ A;  1ALH A;  4UOO A;  3UN2 A;  1KHJ A;  1ELZ A;  3M8Z A;  3M8Y A;  2W5R A;  5IJS A;  4KJG A;  2W5V A;  4KM4 A;  1EJJ A;  1ELX A;  3NKM A;  1P49 A;  3T02 A;  2W8S A;  1ZEF A;  4MY4 A;  4LR2 A;  3CMR A;  4LRD A;  3BDH A;  3BDG A;  4LR8 A;  3SZY A;  3DYC A;  4CXU A;  3OT9 A;  4YR1 A;  1KH5 A;  4GTZ A;  1SHN A;  1ED8 A;  2GSN A;  4NWJ A;  3T00 A;  1HDH A;  1KH9 A;  5INH A;  3NVL A;  5C66 A;  2IUC B;  3MK1 A;  1E2S P;  1ZEB A;  1B8J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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