2AQL | Genus

Total Genus 54

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	54
sequence length	167
structure length	158
Chain Sequence	EVKVKIPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDYANYKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILADHPDAPMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLNYLHDFLKYLAKNSATLFSASDYEVAPPEYHRK

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Dna binding protein
source organism	Homo sapiens
publication title	Multipurpose MRG domain involved in cell senescence and proliferation exhibits structural homology to a DNA-interacting domain. pubmed doi rcsb
molecule keywords	Mortality factor 4-like protein 1
total genus	54
structure length	158
sequence length	167
chains with identical sequence	B
ec nomenclature
pdb deposition date	2005-08-18

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.274.30	Mainly Alpha	Orthogonal Bundle	Enzyme I; Chain A, domain 2	Enzyme I; Chain A, domain 2	2aqlA00

2Y0NA 2AQLA 2N1DB 2F5JA 2LKMB
chains in the Genus database with same CATH superfamily

2R93A 3EZBA 2HWGA 2X0OA 3FKIA 3GTGA 4BAAA 3GTQA 2F5JA 2MQAA 2Y0NA 2LPIA 1T6PA 2LYIA 2CW0D 1K83A 2A69D 3U44A 3LR2A 4C5SA 4FBSA 1Y1WA 1T6JA 2X0PA 2YU9A 2JA6A 2N1DB 2LPJA 1W27A 3NZ4A 2MP0A 2FIOA 1I3QA 1HQMD 2VUMA 3H0GA 4C5RA 4CEJA 1TWAA 2FIPA 1ZYRD 2A68D 4CEIA 4QIWA 2LTHA 2EZCA 2VK9A 1YNJD 1R9TA 1IW7D 1TWCA 2AQLA 1I6VD 1Y1VA 3EZAA 3GTKA 2B63A 4CQ5A 4C2MA 2JA5A 1ZYMA 2A6ED 3LR6A 1Y2MA 3U4QA 4V2RA 2R7ZA 2BE5D 2A6HD 4CEHA 3LRDA 4C6GA 2E2IA 1TWFA 1EZAA 3EZEA 1TWHA 2E2HA 1SFOA 4V2QA 3GTPA 1YNND 2JA7A 2R92A 2K3QA 1WCMA 3CQZA 1EZBA 2LKMB 2K3NA 4C5UA 2N3EA 4BABA 2MX8A 2K3OA 2EZBA 2X0QA 1I50A 3GTOA 2HROA 2MX9A 2NVYA 1SMYD 3GTJA 5IZ2A 2NVXA 3LR8A 1TWGA 3GTLA 2EZAA 2O5JD 3GTMA 2YIIA
chains in the Genus database with same CATH topology

2R93A 2X0OA 3FKIA 3GTGA 3GTQA 2F5JA 2MQAA 2Y0NA 2LPIA 2LYIA 2CW0D 1K83A 2A69D 3U44A 3LR2A 4FBSA 1Y1WA 2X0PA 2YU9A 2JA6A 2N1DB 2LPJA 2FIOA 1I3QA 1HQMD 2VUMA 3H0GA 4CEJA 1TWAA 2FIPA 1ZYRD 2A68D 4CEIA 4QIWA 2LTHA 2VK9A 1YNJD 1R9TA 1IW7D 1TWCA 2AQLA 1I6VD 1Y1VA 3GTKA 2B63A 4C2MA 2JA5A 2A6ED 3LR6A 3U4QA 2R7ZA 2BE5D 2A6HD 4CEHA 3LRDA 2E2IA 1TWFA 1TWHA 2E2HA 1SFOA 3GTPA 1YNND 2JA7A 2R92A 2K3QA 1WCMA 3CQZA 2LKMB 2K3NA 2N3EA 2MX8A 2K3OA 2X0QA 1I50A 3GTOA 2MX9A 2NVYA 1SMYD 3GTJA 5IZ2A 2NVXA 3LR8A 1TWGA 3GTLA 2O5JD 3GTMA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 2Y0N A;  2AQL A;  2N1D B;  2F5J A;  2LKM B; 
#chains in the Genus database with same CATH topology
 2R93 A;  3EZB A;  2HWG A;  2X0O A;  3FKI A;  3GTG A;  4BAA A;  3GTQ A;  2F5J A;  2MQA A;  2Y0N A;  2LPI A;  1T6P A;  2LYI A;  2CW0 D;  1K83 A;  2A69 D;  3U44 A;  3LR2 A;  4C5S A;  4FBS A;  1Y1W A;  1T6J A;  2X0P A;  2YU9 A;  2JA6 A;  2N1D B;  2LPJ A;  1W27 A;  3NZ4 A;  2MP0 A;  2FIO A;  1I3Q A;  1HQM D;  2VUM A;  3H0G A;  4C5R A;  4CEJ A;  1TWA A;  2FIP A;  1ZYR D;  2A68 D;  4CEI A;  4QIW A;  2LTH A;  2EZC A;  2VK9 A;  1YNJ D;  1R9T A;  1IW7 D;  1TWC A;  2AQL A;  1I6V D;  1Y1V A;  3EZA A;  3GTK A;  2B63 A;  4CQ5 A;  4C2M A;  2JA5 A;  1ZYM A;  2A6E D;  3LR6 A;  1Y2M A;  3U4Q A;  4V2R A;  2R7Z A;  2BE5 D;  2A6H D;  4CEH A;  3LRD A;  4C6G A;  2E2I A;  1TWF A;  1EZA A;  3EZE A;  1TWH A;  2E2H A;  1SFO A;  4V2Q A;  3GTP A;  1YNN D;  2JA7 A;  2R92 A;  2K3Q A;  1WCM A;  3CQZ A;  1EZB A;  2LKM B;  2K3N A;  4C5U A;  2N3E A;  4BAB A;  2MX8 A;  2K3O A;  2EZB A;  2X0Q A;  1I50 A;  3GTO A;  2HRO A;  2MX9 A;  2NVY A;  1SMY D;  3GTJ A;  5IZ2 A;  2NVX A;  3LR8 A;  1TWG A;  3GTL A;  2EZA A;  2O5J D;  3GTM A;  2YII A; 
#chains in the Genus database with same CATH homology
 2R93 A;  2X0O A;  3FKI A;  3GTG A;  3GTQ A;  2F5J A;  2MQA A;  2Y0N A;  2LPI A;  2LYI A;  2CW0 D;  1K83 A;  2A69 D;  3U44 A;  3LR2 A;  4FBS A;  1Y1W A;  2X0P A;  2YU9 A;  2JA6 A;  2N1D B;  2LPJ A;  2FIO A;  1I3Q A;  1HQM D;  2VUM A;  3H0G A;  4CEJ A;  1TWA A;  2FIP A;  1ZYR D;  2A68 D;  4CEI A;  4QIW A;  2LTH A;  2VK9 A;  1YNJ D;  1R9T A;  1IW7 D;  1TWC A;  2AQL A;  1I6V D;  1Y1V A;  3GTK A;  2B63 A;  4C2M A;  2JA5 A;  2A6E D;  3LR6 A;  3U4Q A;  2R7Z A;  2BE5 D;  2A6H D;  4CEH A;  3LRD A;  2E2I A;  1TWF A;  1TWH A;  2E2H A;  1SFO A;  3GTP A;  1YNN D;  2JA7 A;  2R92 A;  2K3Q A;  1WCM A;  3CQZ A;  2LKM B;  2K3N A;  2N3E A;  2MX8 A;  2K3O A;  2X0Q A;  1I50 A;  3GTO A;  2MX9 A;  2NVY A;  1SMY D;  3GTJ A;  5IZ2 A;  2NVX A;  3LR8 A;  1TWG A;  3GTL A;  2O5J D;  3GTM A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2AQLA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization