2AQLA

Crystal structure of the mrg15 mrg domain
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
167
structure length
158
Chain Sequence
EVKVKIPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDYANYKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILADHPDAPMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLNYLHDFLKYLAKNSATLFSASDYEVAPPEYHRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Multipurpose MRG domain involved in cell senescence and proliferation exhibits structural homology to a DNA-interacting domain.
pubmed doi rcsb
molecule tags Dna binding protein
source organism Homo sapiens
molecule keywords Mortality factor 4-like protein 1
total genus 54
structure length 158
sequence length 167
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-08-18
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.30 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 Enzyme I; Chain A, domain 2 2aqlA00
2AQLA 2F5JA 2LKMB 2Y0NA 2N1DB
chains in the Genus database with same CATH superfamily
2K3QA 1EZBA 4CEHA 2VUMA 1ZYMA 2A69D 3U4QA 2NVYA 4BAAA 2EZAA 1TWAA 1YNJD 3GTKA 2LPJA 4V2QA 2N3EA 1T6PA 4BABA 2E2IA 3NZ4A 1YNND 1TWFA 2B63A 1I3QA 1TWCA 2FIOA 2N1DB 1HQMD 2YU9A 2BE5D 2A68D 4C5UA 3GTLA 2K3NA 4QIWA 4CEJA 3GTOA 1Y1WA 4CQ5A 1IW7D 3GTGA 3LRDA 1R9TA 1W27A 2HROA 1Y2MA 2R7ZA 2VK9A 4FBSA 3LR6A 2O5JD 2EZCA 4C5RA 2LKMB 2R93A 2LPIA 3EZAA 2A6ED 3GTMA 1ZYRD 2CW0D 4C5SA 1SFOA 4C2MA 2MQAA 2X0QA 2LTHA 3H0GA 1TWGA 2MX9A 2MP0A 4V2RA 2F5JA 3GTJA 2JA6A 1EZAA 2AQLA 3CQZA 1TWHA 2E2HA 3FKIA 3LR2A 2X0PA 1I50A 1WCMA 2Y0NA 3LR8A 1I6VD 3U44A 2FIPA 2HWGA 2NVXA 2LYIA 2JA7A 1SMYD 3GTQA 1T6JA 2JA5A 3EZBA 2MX8A 2EZBA 3GTPA 2A6HD 1K83A 5IZ2A 1Y1VA 2YIIA 4CEIA 2X0OA 2K3OA 2R92A 3EZEA 4C6GA
chains in the Genus database with same CATH topology
2K3QA 4CEHA 2VUMA 2A69D 3U4QA 2NVYA 1TWAA 1YNJD 3GTKA 2LPJA 2N3EA 2E2IA 1YNND 1TWFA 2B63A 1I3QA 1TWCA 2FIOA 2N1DB 1HQMD 2YU9A 2BE5D 2A68D 3GTLA 2K3NA 4QIWA 4CEJA 3GTOA 1Y1WA 1IW7D 3GTGA 3LRDA 1R9TA 2R7ZA 2VK9A 4FBSA 3LR6A 2O5JD 2LKMB 2R93A 2LPIA 2A6ED 3GTMA 1ZYRD 2CW0D 1SFOA 4C2MA 2MQAA 2X0QA 2LTHA 3H0GA 1TWGA 2MX9A 2F5JA 3GTJA 2JA6A 2AQLA 3CQZA 1TWHA 2E2HA 3FKIA 3LR2A 2X0PA 1I50A 1WCMA 2Y0NA 3LR8A 1I6VD 3U44A 2FIPA 2NVXA 2LYIA 2JA7A 1SMYD 3GTQA 2JA5A 2MX8A 3GTPA 2A6HD 1K83A 5IZ2A 1Y1VA 4CEIA 2X0OA 2K3OA 2R92A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2AQL A;  2F5J A;  2LKM B;  2Y0N A;  2N1D B; 
#chains in the Genus database with same CATH topology
 2K3Q A;  1EZB A;  4CEH A;  2VUM A;  1ZYM A;  2A69 D;  3U4Q A;  2NVY A;  4BAA A;  2EZA A;  1TWA A;  1YNJ D;  3GTK A;  2LPJ A;  4V2Q A;  2N3E A;  1T6P A;  4BAB A;  2E2I A;  3NZ4 A;  1YNN D;  1TWF A;  2B63 A;  1I3Q A;  1TWC A;  2FIO A;  2N1D B;  1HQM D;  2YU9 A;  2BE5 D;  2A68 D;  4C5U A;  3GTL A;  2K3N A;  4QIW A;  4CEJ A;  3GTO A;  1Y1W A;  4CQ5 A;  1IW7 D;  3GTG A;  3LRD A;  1R9T A;  1W27 A;  2HRO A;  1Y2M A;  2R7Z A;  2VK9 A;  4FBS A;  3LR6 A;  2O5J D;  2EZC A;  4C5R A;  2LKM B;  2R93 A;  2LPI A;  3EZA A;  2A6E D;  3GTM A;  1ZYR D;  2CW0 D;  4C5S A;  1SFO A;  4C2M A;  2MQA A;  2X0Q A;  2LTH A;  3H0G A;  1TWG A;  2MX9 A;  2MP0 A;  4V2R A;  2F5J A;  3GTJ A;  2JA6 A;  1EZA A;  2AQL A;  3CQZ A;  1TWH A;  2E2H A;  3FKI A;  3LR2 A;  2X0P A;  1I50 A;  1WCM A;  2Y0N A;  3LR8 A;  1I6V D;  3U44 A;  2FIP A;  2HWG A;  2NVX A;  2LYI A;  2JA7 A;  1SMY D;  3GTQ A;  1T6J A;  2JA5 A;  3EZB A;  2MX8 A;  2EZB A;  3GTP A;  2A6H D;  1K83 A;  5IZ2 A;  1Y1V A;  2YII A;  4CEI A;  2X0O A;  2K3O A;  2R92 A;  3EZE A;  4C6G A; 
#chains in the Genus database with same CATH homology
 2K3Q A;  4CEH A;  2VUM A;  2A69 D;  3U4Q A;  2NVY A;  1TWA A;  1YNJ D;  3GTK A;  2LPJ A;  2N3E A;  2E2I A;  1YNN D;  1TWF A;  2B63 A;  1I3Q A;  1TWC A;  2FIO A;  2N1D B;  1HQM D;  2YU9 A;  2BE5 D;  2A68 D;  3GTL A;  2K3N A;  4QIW A;  4CEJ A;  3GTO A;  1Y1W A;  1IW7 D;  3GTG A;  3LRD A;  1R9T A;  2R7Z A;  2VK9 A;  4FBS A;  3LR6 A;  2O5J D;  2LKM B;  2R93 A;  2LPI A;  2A6E D;  3GTM A;  1ZYR D;  2CW0 D;  1SFO A;  4C2M A;  2MQA A;  2X0Q A;  2LTH A;  3H0G A;  1TWG A;  2MX9 A;  2F5J A;  3GTJ A;  2JA6 A;  2AQL A;  3CQZ A;  1TWH A;  2E2H A;  3FKI A;  3LR2 A;  2X0P A;  1I50 A;  1WCM A;  2Y0N A;  3LR8 A;  1I6V D;  3U44 A;  2FIP A;  2NVX A;  2LYI A;  2JA7 A;  1SMY D;  3GTQ A;  2JA5 A;  2MX8 A;  3GTP A;  2A6H D;  1K83 A;  5IZ2 A;  1Y1V A;  4CEI A;  2X0O A;  2K3O A;  2R92 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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