2AQLA

Crystal structure of the mrg15 mrg domain
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
167
structure length
158
Chain Sequence
EVKVKIPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDYANYKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILADHPDAPMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLNYLHDFLKYLAKNSATLFSASDYEVAPPEYHRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Multipurpose MRG domain involved in cell senescence and proliferation exhibits structural homology to a DNA-interacting domain.
pubmed doi rcsb
molecule tags Dna binding protein
source organism Homo sapiens
molecule keywords Mortality factor 4-like protein 1
total genus 54
structure length 158
sequence length 167
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-08-18
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.30 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 Enzyme I; Chain A, domain 2 2aqlA00
2Y0NA 2F5JA 2AQLA 2LKMB 2N1DB
chains in the Genus database with same CATH superfamily
3U4QA 1R9TA 1Y1VA 3EZAA 1TWFA 1YNND 2VK9A 4C5UA 3EZEA 1IW7D 1TWAA 1EZBA 3LR2A 4V2QA 2R92A 4CEHA 2E2IA 2VUMA 4CEJA 3LRDA 4BAAA 3GTGA 1TWCA 2YIIA 1K83A 4V2RA 2A69D 4FBSA 3H0GA 2NVYA 3U44A 2HROA 3GTKA 2F5JA 2FIOA 3NZ4A 1Y1WA 1I3QA 2NVXA 2A6ED 3GTJA 3LR6A 2JA5A 4C2MA 2LPJA 3FKIA 2X0PA 1SMYD 2R7ZA 2LTHA 1ZYMA 4QIWA 4C6GA 2LPIA 2EZAA 2K3OA 2JA7A 2LYIA 3GTQA 3GTPA 3GTOA 2N3EA 2Y0NA 4CEIA 2E2HA 3LR8A 3EZBA 2MQAA 2AQLA 2X0OA 2CW0D 1SFOA 2LKMB 2K3NA 2JA6A 2HWGA 1TWGA 3GTLA 5IZ2A 2MX8A 2EZBA 2BE5D 2O5JD 2X0QA 2B63A 1I6VD 1HQMD 1I50A 1T6PA 2A68D 1W27A 2A6HD 2K3QA 2R93A 4BABA 1YNJD 2MX9A 2MP0A 4C5SA 3GTMA 1WCMA 1Y2MA 3CQZA 1ZYRD 4CQ5A 1EZAA 2EZCA 1T6JA 1TWHA 4C5RA 2FIPA 2N1DB 2YU9A
chains in the Genus database with same CATH topology
3U4QA 1R9TA 1Y1VA 1TWFA 1YNND 2VK9A 1IW7D 1TWAA 3LR2A 2R92A 4CEHA 2E2IA 2VUMA 4CEJA 3LRDA 3GTGA 1TWCA 1K83A 2A69D 4FBSA 3H0GA 2NVYA 3U44A 3GTKA 2F5JA 2FIOA 1Y1WA 1I3QA 2NVXA 2A6ED 3GTJA 3LR6A 2JA5A 4C2MA 2LPJA 3FKIA 2X0PA 1SMYD 2R7ZA 2LTHA 4QIWA 2LPIA 2K3OA 2JA7A 2LYIA 3GTQA 3GTPA 3GTOA 2N3EA 2Y0NA 4CEIA 2E2HA 3LR8A 2MQAA 2AQLA 2X0OA 2CW0D 1SFOA 2LKMB 2K3NA 2JA6A 1TWGA 3GTLA 5IZ2A 2MX8A 2BE5D 2O5JD 2X0QA 2B63A 1I6VD 1HQMD 1I50A 2A68D 2A6HD 2K3QA 2R93A 1YNJD 2MX9A 3GTMA 1WCMA 3CQZA 1ZYRD 1TWHA 2FIPA 2N1DB 2YU9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Y0N A;  2F5J A;  2AQL A;  2LKM B;  2N1D B; 
#chains in the Genus database with same CATH topology
 3U4Q A;  1R9T A;  1Y1V A;  3EZA A;  1TWF A;  1YNN D;  2VK9 A;  4C5U A;  3EZE A;  1IW7 D;  1TWA A;  1EZB A;  3LR2 A;  4V2Q A;  2R92 A;  4CEH A;  2E2I A;  2VUM A;  4CEJ A;  3LRD A;  4BAA A;  3GTG A;  1TWC A;  2YII A;  1K83 A;  4V2R A;  2A69 D;  4FBS A;  3H0G A;  2NVY A;  3U44 A;  2HRO A;  3GTK A;  2F5J A;  2FIO A;  3NZ4 A;  1Y1W A;  1I3Q A;  2NVX A;  2A6E D;  3GTJ A;  3LR6 A;  2JA5 A;  4C2M A;  2LPJ A;  3FKI A;  2X0P A;  1SMY D;  2R7Z A;  2LTH A;  1ZYM A;  4QIW A;  4C6G A;  2LPI A;  2EZA A;  2K3O A;  2JA7 A;  2LYI A;  3GTQ A;  3GTP A;  3GTO A;  2N3E A;  2Y0N A;  4CEI A;  2E2H A;  3LR8 A;  3EZB A;  2MQA A;  2AQL A;  2X0O A;  2CW0 D;  1SFO A;  2LKM B;  2K3N A;  2JA6 A;  2HWG A;  1TWG A;  3GTL A;  5IZ2 A;  2MX8 A;  2EZB A;  2BE5 D;  2O5J D;  2X0Q A;  2B63 A;  1I6V D;  1HQM D;  1I50 A;  1T6P A;  2A68 D;  1W27 A;  2A6H D;  2K3Q A;  2R93 A;  4BAB A;  1YNJ D;  2MX9 A;  2MP0 A;  4C5S A;  3GTM A;  1WCM A;  1Y2M A;  3CQZ A;  1ZYR D;  4CQ5 A;  1EZA A;  2EZC A;  1T6J A;  1TWH A;  4C5R A;  2FIP A;  2N1D B;  2YU9 A; 
#chains in the Genus database with same CATH homology
 3U4Q A;  1R9T A;  1Y1V A;  1TWF A;  1YNN D;  2VK9 A;  1IW7 D;  1TWA A;  3LR2 A;  2R92 A;  4CEH A;  2E2I A;  2VUM A;  4CEJ A;  3LRD A;  3GTG A;  1TWC A;  1K83 A;  2A69 D;  4FBS A;  3H0G A;  2NVY A;  3U44 A;  3GTK A;  2F5J A;  2FIO A;  1Y1W A;  1I3Q A;  2NVX A;  2A6E D;  3GTJ A;  3LR6 A;  2JA5 A;  4C2M A;  2LPJ A;  3FKI A;  2X0P A;  1SMY D;  2R7Z A;  2LTH A;  4QIW A;  2LPI A;  2K3O A;  2JA7 A;  2LYI A;  3GTQ A;  3GTP A;  3GTO A;  2N3E A;  2Y0N A;  4CEI A;  2E2H A;  3LR8 A;  2MQA A;  2AQL A;  2X0O A;  2CW0 D;  1SFO A;  2LKM B;  2K3N A;  2JA6 A;  1TWG A;  3GTL A;  5IZ2 A;  2MX8 A;  2BE5 D;  2O5J D;  2X0Q A;  2B63 A;  1I6V D;  1HQM D;  1I50 A;  2A68 D;  2A6H D;  2K3Q A;  2R93 A;  1YNJ D;  2MX9 A;  3GTM A;  1WCM A;  3CQZ A;  1ZYR D;  1TWH A;  2FIP A;  2N1D B;  2YU9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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