3NZ4A

Crystal structure of a taxus phenylalanine aminomutase
Total Genus 257
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
257
sequence length
670
structure length
653
Chain Sequence
b'SRSHVKDILGLINTFNEVKKITVDGTTPITVAHVAALARRHDVKVALEAEQCRARVETCSSWVQRKAEDGADIYGVTTGFGACSSRRTNQLSELQESLIRCLLAGVFTKGCASSVDELPATVTRSAMLLRLNSFTYGCSGIRWEVMEALEKLLNSNVSPKVPLRGSVSDLIPLAYIAGLLIGKPSVIARIGDDVEVPAPEALSRVGLRPFKLQAKEGLALVNGTSFATALASTVMYDANVLLLLVETLCGMFCEVIFGREEFAHPLIHKVKPHPGQIESAELLEWLLRSSPFQDLSREYYSIDKLKKPKQDRYALRSSPQWLAPLVQTIRDATTTVETEVNSANDNPIIDHANDRALHGANFQGSAVGFYMDYVRIAVAGLGKLLFAQFTELMIEYYSNGLPGNLSLGPDLSVDYGLKGLDIAMAAYSSELQYLANPVTTHVHSAEQHNQDINSLALISARKTDEALDILKLMIASHLTAMCQAVDLRQLEEALVKVVENVVSTLADECGLPNDTKARLLYVAKAVPVYTYLESPCDPTLPLLLGLKQSCFGSILALHKETDTLVDRLAEFEKRLSDRLENEMTAVRVLYEKVRIQGSRFLPFYRFVRDELDTGVMSARREQTPQEDVQKVFDAIADGRITVPLLHCLQGFLG'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Phenylalanine ammonia-lyase
publication title Mechanistic, mutational, and structural evaluation of a taxus phenylalanine aminomutase.
pubmed doi rcsb
source organism Taxus canadensis
molecule tags Lyase
total genus 257
structure length 653
sequence length 670
chains with identical sequence B
ec nomenclature ec 4.3.1.24: Phenylalanine ammonia-lyase.
pdb deposition date 2010-07-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.20 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 Phenylalanine ammonia-lyase 1; domain 3 3nz4A03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 3nz4A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 3nz4A02
1DCNA 1XWOA 1GK2A 1K7WA 1YFMA 2O78A 4NLEA 1FURA 3CZOA 2HVGA 5HW2A 1YFEA 1GKJA 4V2QA 3GTDA 1U16A 1Y2MA 5EYVA 1GKMA 4BAAA 1FUOA 1FUQA 5D6BA 1EB4A 1Q5NA 3RD8A 1K62A 3NZ4A 2O7EA 1VDKA 1HY0A 2NYFA 3OCEA 1B8FA 4FFXA 3KDZA 2NYNA 2FUSA 3QBPA 2J91A 4CQ5A 3BHGA 4MX2A 1AUWA 1DOFA 1FUPA 4EEIA 1I0AA 4ADMA 2O7DA 1GK3A 4C5UA 2YIIA 5F92A 3E04A 1TJUA 4C5RA 2E9FA 4C5SA 3C8TA 2RJRA 3R6YA 1RE5A 3R6QA 4ADLA 2RJSA 1C3CA 1TJ7A 3TV2A 2VD6A 4V2RA 2QGAB 1C3UA 3R6VA 2O7BA 3KDYA 1T6JA 4APAA 4NSLA 1TJWA 1U15A 2PTQA 4APBA 2PTSA 4HGVA 1KQ7A 1JSWA 3RRPA 1T6PA 2O6YA 4FLCA 5F91A 1TJVA 1J3UA 3NO9A 1YISA 4EFCA 3OCFA 4BABA 3GZHA 4C6GA 2OHYA 2O7FA 2QVEA 1HY1A 5EYTA 2PTRA 3UNVA 1W27A 2X75A 2PFMA
chains in the Genus database with same CATH superfamily
1IW7D 1I6VD 1DCNA 1XWOA 2Y0NA 1GK2A 1K7WA 2MX8A 1YFMA 1YNJD 1TWAA 2O78A 5IZ2A 1FURA 4NLEA 1TWGA 1I50A 5M0JA 3GTKA 3CZOA 2HVGA 5HW2A 1YFEA 2F5JA 1GKJA 4V2QA 2R7ZA 3H0GA 1U16A 3GTDA 1Y2MA 5EYVA 2R92A 1GKMA 4BAAA 2JA5A 1FUOA 2K3QA 1FUQA 2X0OA 5H8WA 2R93A 3GTGA 5D6BA 1EB4A 1Q5NA 3RD8A 1K62A 1HQMD 2LYIA 3NZ4A 2O7EA 1VDKA 2HWGA 2X0QA 1HY0A 2NYFA 2VSFA 2FIPA 1XL7A 3LR6A 3OCEA 2FIOA 1B8FA 4C2MA 2LPIA 4FFXA 4CEJA 3KDZA 2K3OA 2VL7A 2NYNA 2JA6A 2EZCA 1SMYD 2A6HD 1TWHA 2FUSA 3FKIA 3QBPA 2J91A 2VK9A 1XMDA 3CRW1 2MQAA 2LPJA 4CQ5A 2VUMA 3BHGA 3EZEA 1K83A 4MX2A 1AUWA 1DOFA 2LTHA 1TWFA 1FUPA 1I0AA 4ADMA 2O7DA 4EEIA 1GK3A 2FELA 2B63A 1XMCA 3CRVA 4C5UA 2YIIA 4CEHA 2X0PA 1EZBA 3EZAA 5F92A 3E04A 3GTJA 1TJUA 4C5RA 2N1DB 2E9FA 4C5SA 3C8TA 4A15A 1XLYA 2RJRA 3U44A 2A68D 3R6YA 3GTOA 1RE5A 2EZBA 3GTLA 3R6QA 4ADLA 2RJSA 2E2HA 1C3CA 3EZBA 1TWCA 2HROA 2MX9A 1TJ7A 3TV2A 2NVXA 2VD6A 4V2RA 3U4QA 2QGAB 1C3UA 2FENA 3R6VA 3LR2A 2O5JD 2A6ED 1EZAA 4WNLA 2O7BA 2JA7A 3KDYA 1T6JA 4APAA 1R9TA 3GTPA 2CW0D 5M0IA 2N3EA 1TJWA 4NSLA 1U15A 2PTQA 3LRDA 4APBA 2PTSA 2E2IA 4HGVA 1KQ7A 1Y1WA 1JSWA 3RRPA 1ZYRD 1T6PA 2O6YA 4FLCA 4FBSA 5F91A 4QIWA 1TJVA 1J3UA 3NO9A 2MP0A 1YISA 4EFCA 3OCFA 1SFOA 1WCMA 2A69D 4BABA 1Y1VA 2K3NA 3GTQA 3GZHA 4C6GA 2OHYA 2YU9A 3GTMA 2EZAA 2O7FA 2LKMB 2QVEA 3LR8A 3CQZA 2NVYA 1HY1A 5EYTA 2PTRA 2AQLA 3UNVA 1I3QA 1W27A 1YNND 1ZYMA 4CEIA 1XL8A 2BE5D 2X75A 2PFMA
chains in the Genus database with same CATH topology
1DCNA 1XWOA 1GK2A 1K7WA 1YFMA 2O78A 4NLEA 1FURA 3CZOA 2HVGA 5HW2A 1YFEA 1GKJA 4V2QA 3GTDA 1U16A 1Y2MA 5EYVA 1GKMA 4BAAA 1FUOA 1FUQA 5D6BA 1EB4A 1Q5NA 3RD8A 1K62A 3NZ4A 2O7EA 1VDKA 1HY0A 2NYFA 3OCEA 1B8FA 4FFXA 3KDZA 2NYNA 2FUSA 3QBPA 2J91A 4CQ5A 3BHGA 4MX2A 1AUWA 1DOFA 1FUPA 4EEIA 1I0AA 4ADMA 2O7DA 1GK3A 4C5UA 2YIIA 5F92A 3E04A 1TJUA 4C5RA 2E9FA 4C5SA 3C8TA 2RJRA 3R6YA 1RE5A 3R6QA 4ADLA 2RJSA 1C3CA 1TJ7A 3TV2A 2VD6A 4V2RA 2QGAB 1C3UA 3R6VA 2O7BA 3KDYA 1T6JA 4APAA 4NSLA 1TJWA 1U15A 2PTQA 4APBA 2PTSA 4HGVA 1KQ7A 1JSWA 3RRPA 1T6PA 2O6YA 4FLCA 5F91A 1TJVA 1J3UA 3NO9A 1YISA 4EFCA 3OCFA 4BABA 3GZHA 4C6GA 2OHYA 2O7FA 2QVEA 1HY1A 5EYTA 2PTRA 3UNVA 1W27A 2X75A 2PFMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DCN A;  1XWO A;  1GK2 A;  1K7W A;  1YFM A;  2O78 A;  4NLE A;  1FUR A;  3CZO A;  2HVG A;  5HW2 A;  1YFE A;  1GKJ A;  4V2Q A;  3GTD A;  1U16 A;  1Y2M A;  5EYV A;  1GKM A;  4BAA A;  1FUO A;  1FUQ A;  5D6B A;  1EB4 A;  1Q5N A;  3RD8 A;  1K62 A;  3NZ4 A;  2O7E A;  1VDK A;  1HY0 A;  2NYF A;  3OCE A;  1B8F A;  4FFX A;  3KDZ A;  2NYN A;  2FUS A;  3QBP A;  2J91 A;  4CQ5 A;  3BHG A;  4MX2 A;  1AUW A;  1DOF A;  1FUP A;  4EEI A;  1I0A A;  4ADM A;  2O7D A;  1GK3 A;  4C5U A;  2YII A;  5F92 A;  3E04 A;  1TJU A;  4C5R A;  2E9F A;  4C5S A;  3C8T A;  2RJR A;  3R6Y A;  1RE5 A;  3R6Q A;  4ADL A;  2RJS A;  1C3C A;  1TJ7 A;  3TV2 A;  2VD6 A;  4V2R A;  2QGA B;  1C3U A;  3R6V A;  2O7B A;  3KDY A;  1T6J A;  4APA A;  4NSL A;  1TJW A;  1U15 A;  2PTQ A;  4APB A;  2PTS A;  4HGV A;  1KQ7 A;  1JSW A;  3RRP A;  1T6P A;  2O6Y A;  4FLC A;  5F91 A;  1TJV A;  1J3U A;  3NO9 A;  1YIS A;  4EFC A;  3OCF A;  4BAB A;  3GZH A;  4C6G A;  2OHY A;  2O7F A;  2QVE A;  1HY1 A;  5EYT A;  2PTR A;  3UNV A;  1W27 A;  2X75 A;  2PFM A; 
#chains in the Genus database with same CATH topology
 1IW7 D;  1I6V D;  1DCN A;  1XWO A;  2Y0N A;  1GK2 A;  1K7W A;  2MX8 A;  1YFM A;  1YNJ D;  1TWA A;  2O78 A;  5IZ2 A;  1FUR A;  4NLE A;  1TWG A;  1I50 A;  5M0J A;  3GTK A;  3CZO A;  2HVG A;  5HW2 A;  1YFE A;  2F5J A;  1GKJ A;  4V2Q A;  2R7Z A;  3H0G A;  1U16 A;  3GTD A;  1Y2M A;  5EYV A;  2R92 A;  1GKM A;  4BAA A;  2JA5 A;  1FUO A;  2K3Q A;  1FUQ A;  2X0O A;  5H8W A;  2R93 A;  3GTG A;  5D6B A;  1EB4 A;  1Q5N A;  3RD8 A;  1K62 A;  1HQM D;  2LYI A;  3NZ4 A;  2O7E A;  1VDK A;  2HWG A;  2X0Q A;  1HY0 A;  2NYF A;  2VSF A;  2FIP A;  1XL7 A;  3LR6 A;  3OCE A;  2FIO A;  1B8F A;  4C2M A;  2LPI A;  4FFX A;  4CEJ A;  3KDZ A;  2K3O A;  2VL7 A;  2NYN A;  2JA6 A;  2EZC A;  1SMY D;  2A6H D;  1TWH A;  2FUS A;  3FKI A;  3QBP A;  2J91 A;  2VK9 A;  1XMD A;  3CRW 1;  2MQA A;  2LPJ A;  4CQ5 A;  2VUM A;  3BHG A;  3EZE A;  1K83 A;  4MX2 A;  1AUW A;  1DOF A;  2LTH A;  1TWF A;  1FUP A;  1I0A A;  4ADM A;  2O7D A;  4EEI A;  1GK3 A;  2FEL A;  2B63 A;  1XMC A;  3CRV A;  4C5U A;  2YII A;  4CEH A;  2X0P A;  1EZB A;  3EZA A;  5F92 A;  3E04 A;  3GTJ A;  1TJU A;  4C5R A;  2N1D B;  2E9F A;  4C5S A;  3C8T A;  4A15 A;  1XLY A;  2RJR A;  3U44 A;  2A68 D;  3R6Y A;  3GTO A;  1RE5 A;  2EZB A;  3GTL A;  3R6Q A;  4ADL A;  2RJS A;  2E2H A;  1C3C A;  3EZB A;  1TWC A;  2HRO A;  2MX9 A;  1TJ7 A;  3TV2 A;  2NVX A;  2VD6 A;  4V2R A;  3U4Q A;  2QGA B;  1C3U A;  2FEN A;  3R6V A;  3LR2 A;  2O5J D;  2A6E D;  1EZA A;  4WNL A;  2O7B A;  2JA7 A;  3KDY A;  1T6J A;  4APA A;  1R9T A;  3GTP A;  2CW0 D;  5M0I A;  2N3E A;  1TJW A;  4NSL A;  1U15 A;  2PTQ A;  3LRD A;  4APB A;  2PTS A;  2E2I A;  4HGV A;  1KQ7 A;  1Y1W A;  1JSW A;  3RRP A;  1ZYR D;  1T6P A;  2O6Y A;  4FLC A;  4FBS A;  5F91 A;  4QIW A;  1TJV A;  1J3U A;  3NO9 A;  2MP0 A;  1YIS A;  4EFC A;  3OCF A;  1SFO A;  1WCM A;  2A69 D;  4BAB A;  1Y1V A;  2K3N A;  3GTQ A;  3GZH A;  4C6G A;  2OHY A;  2YU9 A;  3GTM A;  2EZA A;  2O7F A;  2LKM B;  2QVE A;  3LR8 A;  3CQZ A;  2NVY A;  1HY1 A;  5EYT A;  2PTR A;  2AQL A;  3UNV A;  1I3Q A;  1W27 A;  1YNN D;  1ZYM A;  4CEI A;  1XL8 A;  2BE5 D;  2X75 A;  2PFM A; 
#chains in the Genus database with same CATH homology
 1DCN A;  1XWO A;  1GK2 A;  1K7W A;  1YFM A;  2O78 A;  4NLE A;  1FUR A;  3CZO A;  2HVG A;  5HW2 A;  1YFE A;  1GKJ A;  4V2Q A;  3GTD A;  1U16 A;  1Y2M A;  5EYV A;  1GKM A;  4BAA A;  1FUO A;  1FUQ A;  5D6B A;  1EB4 A;  1Q5N A;  3RD8 A;  1K62 A;  3NZ4 A;  2O7E A;  1VDK A;  1HY0 A;  2NYF A;  3OCE A;  1B8F A;  4FFX A;  3KDZ A;  2NYN A;  2FUS A;  3QBP A;  2J91 A;  4CQ5 A;  3BHG A;  4MX2 A;  1AUW A;  1DOF A;  1FUP A;  4EEI A;  1I0A A;  4ADM A;  2O7D A;  1GK3 A;  4C5U A;  2YII A;  5F92 A;  3E04 A;  1TJU A;  4C5R A;  2E9F A;  4C5S A;  3C8T A;  2RJR A;  3R6Y A;  1RE5 A;  3R6Q A;  4ADL A;  2RJS A;  1C3C A;  1TJ7 A;  3TV2 A;  2VD6 A;  4V2R A;  2QGA B;  1C3U A;  3R6V A;  2O7B A;  3KDY A;  1T6J A;  4APA A;  4NSL A;  1TJW A;  1U15 A;  2PTQ A;  4APB A;  2PTS A;  4HGV A;  1KQ7 A;  1JSW A;  3RRP A;  1T6P A;  2O6Y A;  4FLC A;  5F91 A;  1TJV A;  1J3U A;  3NO9 A;  1YIS A;  4EFC A;  3OCF A;  4BAB A;  3GZH A;  4C6G A;  2OHY A;  2O7F A;  2QVE A;  1HY1 A;  5EYT A;  2PTR A;  3UNV A;  1W27 A;  2X75 A;  2PFM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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