3NZ4A

Crystal structure of a taxus phenylalanine aminomutase
Total Genus 257
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
257
sequence length
670
structure length
653
Chain Sequence
b'SRSHVKDILGLINTFNEVKKITVDGTTPITVAHVAALARRHDVKVALEAEQCRARVETCSSWVQRKAEDGADIYGVTTGFGACSSRRTNQLSELQESLIRCLLAGVFTKGCASSVDELPATVTRSAMLLRLNSFTYGCSGIRWEVMEALEKLLNSNVSPKVPLRGSVSDLIPLAYIAGLLIGKPSVIARIGDDVEVPAPEALSRVGLRPFKLQAKEGLALVNGTSFATALASTVMYDANVLLLLVETLCGMFCEVIFGREEFAHPLIHKVKPHPGQIESAELLEWLLRSSPFQDLSREYYSIDKLKKPKQDRYALRSSPQWLAPLVQTIRDATTTVETEVNSANDNPIIDHANDRALHGANFQGSAVGFYMDYVRIAVAGLGKLLFAQFTELMIEYYSNGLPGNLSLGPDLSVDYGLKGLDIAMAAYSSELQYLANPVTTHVHSAEQHNQDINSLALISARKTDEALDILKLMIASHLTAMCQAVDLRQLEEALVKVVENVVSTLADECGLPNDTKARLLYVAKAVPVYTYLESPCDPTLPLLLGLKQSCFGSILALHKETDTLVDRLAEFEKRLSDRLENEMTAVRVLYEKVRIQGSRFLPFYRFVRDELDTGVMSARREQTPQEDVQKVFDAIADGRITVPLLHCLQGFLG'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Phenylalanine ammonia-lyase
molecule tags Lyase
source organism Taxus canadensis
publication title Mechanistic, mutational, and structural evaluation of a taxus phenylalanine aminomutase.
pubmed doi rcsb
total genus 257
structure length 653
sequence length 670
chains with identical sequence B
ec nomenclature ec 4.3.1.24: Phenylalanine ammonia-lyase.
pdb deposition date 2010-07-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.20 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 Phenylalanine ammonia-lyase 1; domain 3 3nz4A03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 3nz4A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 3nz4A02
5F92A 1Y2MA 2HVGA 1YFMA 1GKJA 1AUWA 1U16A 3NZ4A 3KDZA 3R6VA 2E9FA 1FURA 4C5RA 2NYNA 1W27A 5EYVA 2PTRA 2RJSA 4NSLA 1K62A 5F91A 1U15A 1GK3A 4EEIA 4APAA 3CZOA 1HY1A 2QVEA 4FFXA 1TJUA 2O7EA 2NYFA 1I0AA 1GK2A 3QBPA 5D6BA 4BAAA 2O7BA 1VDKA 1J3UA 2YIIA 4C5SA 1T6JA 1T6PA 3R6QA 4V2RA 3E04A 4EFCA 3KDYA 1DCNA 1FUOA 1RE5A 1JSWA 1HY0A 3OCEA 4ADMA 2RJRA 1TJWA 4APBA 2O6YA 2QGAB 1FUPA 4FLCA 4BABA 2FUSA 1TJVA 1B8FA 3OCFA 1Q5NA 5HW2A 1GKMA 4CQ5A 2OHYA 2X75A 4ADLA 2O78A 4NLEA 3TV2A 2O7FA 4V2QA 4C6GA 1K7WA 2J91A 1EB4A 1KQ7A 3C8TA 4HGVA 4MX2A 2PTQA 3GZHA 1YFEA 2VD6A 1XWOA 3GTDA 3BHGA 1DOFA 4C5UA 1C3CA 3R6YA 3RD8A 1C3UA 3RRPA 2PFMA 5EYTA 2PTSA 1FUQA 3UNVA 1YISA 1TJ7A 3NO9A 2O7DA
chains in the Genus database with same CATH superfamily
1XL8A 5F92A 1Y2MA 2K3QA 2HVGA 3EZEA 1YFMA 2HWGA 1SFOA 1GKJA 1AUWA 1U16A 3NZ4A 2E9FA 3KDZA 3R6VA 3CQZA 2AQLA 1FURA 3LR2A 4C5RA 3LR8A 2HROA 1EZBA 1W27A 2NYNA 3EZAA 1XLYA 5EYVA 1WCMA 2PTRA 2RJSA 2VSFA 4NSLA 1TWGA 1XMDA 1K62A 5F91A 1U15A 1GK3A 4EEIA 1YNJD 4APAA 1SMYD 3CZOA 1HY1A 2QVEA 1TWHA 4FFXA 2X0QA 1TJUA 2K3OA 2LYIA 2O7EA 2LTHA 1I3QA 2NYFA 3GTLA 3EZBA 4FBSA 2NVXA 1GK2A 1I0AA 3QBPA 5D6BA 4BAAA 2LPIA 2R92A 2FELA 2O7BA 1VDKA 1J3UA 2YIIA 4C5SA 1T6JA 2VUMA 2X0PA 1T6PA 2X0OA 3R6QA 3CRW1 2FIPA 4CEIA 4V2RA 3E04A 4EFCA 1XL7A 3KDYA 1DCNA 1FUOA 4WNLA 1RE5A 2EZAA 3GTMA 1JSWA 2E2HA 2JA5A 1HY0A 3OCEA 4ADMA 2FENA 5M0JA 2B63A 2RJRA 1TJWA 2VL7A 4APBA 1I6VD 1K83A 2F5JA 2MX9A 2O6YA 2JA6A 4A15A 2VK9A 3FKIA 1TWFA 1FUPA 2QGAB 4FLCA 2LPJA 4CEHA 4BABA 2FUSA 1TJVA 1B8FA 3OCFA 1Q5NA 3LRDA 2MX8A 5HW2A 1GKMA 4CQ5A 2A69D 2OHYA 2K3NA 3GTQA 2R7ZA 4C2MA 2A6ED 2A68D 1IW7D 1TWAA 3GTPA 2X75A 2N3EA 4ADLA 2O78A 3GTKA 4NLEA 3TV2A 2MP0A 4CEJA 2O7FA 4V2QA 2FIOA 2E2IA 4C6GA 1EZAA 1K7WA 2EZBA 2J91A 3CRVA 2O5JD 2JA7A 1ZYMA 1R9TA 1EB4A 1KQ7A 3C8TA 1HQMD 3H0GA 5IZ2A 2MQAA 3GTJA 4HGVA 2YU9A 2PTQA 3U44A 1Y1WA 3GZHA 2CW0D 1YFEA 2R93A 2VD6A 4MX2A 5H8WA 2A6HD 1XWOA 2Y0NA 3GTDA 2EZCA 1TWCA 1YNND 3BHGA 2BE5D 1DOFA 4C5UA 1C3CA 3R6YA 4QIWA 3RD8A 1C3UA 2NVYA 3U4QA 3GTGA 1ZYRD 3RRPA 5M0IA 2LKMB 1XMCA 2PFMA 5EYTA 2PTSA 1FUQA 3UNVA 3GTOA 3LR6A 1YISA 1TJ7A 3NO9A 2O7DA 1I50A 2N1DB 1Y1VA
chains in the Genus database with same CATH topology
5F92A 1Y2MA 2HVGA 1YFMA 1GKJA 1AUWA 1U16A 3NZ4A 3KDZA 3R6VA 2E9FA 1FURA 4C5RA 2NYNA 1W27A 5EYVA 2PTRA 2RJSA 4NSLA 1K62A 5F91A 1U15A 1GK3A 4EEIA 4APAA 3CZOA 1HY1A 2QVEA 4FFXA 1TJUA 2O7EA 2NYFA 1I0AA 1GK2A 3QBPA 5D6BA 4BAAA 2O7BA 1VDKA 1J3UA 2YIIA 4C5SA 1T6JA 1T6PA 3R6QA 4V2RA 3E04A 4EFCA 3KDYA 1DCNA 1FUOA 1RE5A 1JSWA 1HY0A 3OCEA 4ADMA 2RJRA 1TJWA 4APBA 2O6YA 2QGAB 1FUPA 4FLCA 4BABA 2FUSA 1TJVA 1B8FA 3OCFA 1Q5NA 5HW2A 1GKMA 4CQ5A 2OHYA 2X75A 4ADLA 2O78A 4NLEA 3TV2A 2O7FA 4V2QA 4C6GA 1K7WA 2J91A 1EB4A 1KQ7A 3C8TA 4HGVA 4MX2A 2PTQA 3GZHA 1YFEA 2VD6A 1XWOA 3GTDA 3BHGA 1DOFA 4C5UA 1C3CA 3R6YA 3RD8A 1C3UA 3RRPA 2PFMA 5EYTA 2PTSA 1FUQA 3UNVA 1YISA 1TJ7A 3NO9A 2O7DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5F92 A;  1Y2M A;  2HVG A;  1YFM A;  1GKJ A;  1AUW A;  1U16 A;  3NZ4 A;  3KDZ A;  3R6V A;  2E9F A;  1FUR A;  4C5R A;  2NYN A;  1W27 A;  5EYV A;  2PTR A;  2RJS A;  4NSL A;  1K62 A;  5F91 A;  1U15 A;  1GK3 A;  4EEI A;  4APA A;  3CZO A;  1HY1 A;  2QVE A;  4FFX A;  1TJU A;  2O7E A;  2NYF A;  1I0A A;  1GK2 A;  3QBP A;  5D6B A;  4BAA A;  2O7B A;  1VDK A;  1J3U A;  2YII A;  4C5S A;  1T6J A;  1T6P A;  3R6Q A;  4V2R A;  3E04 A;  4EFC A;  3KDY A;  1DCN A;  1FUO A;  1RE5 A;  1JSW A;  1HY0 A;  3OCE A;  4ADM A;  2RJR A;  1TJW A;  4APB A;  2O6Y A;  2QGA B;  1FUP A;  4FLC A;  4BAB A;  2FUS A;  1TJV A;  1B8F A;  3OCF A;  1Q5N A;  5HW2 A;  1GKM A;  4CQ5 A;  2OHY A;  2X75 A;  4ADL A;  2O78 A;  4NLE A;  3TV2 A;  2O7F A;  4V2Q A;  4C6G A;  1K7W A;  2J91 A;  1EB4 A;  1KQ7 A;  3C8T A;  4HGV A;  4MX2 A;  2PTQ A;  3GZH A;  1YFE A;  2VD6 A;  1XWO A;  3GTD A;  3BHG A;  1DOF A;  4C5U A;  1C3C A;  3R6Y A;  3RD8 A;  1C3U A;  3RRP A;  2PFM A;  5EYT A;  2PTS A;  1FUQ A;  3UNV A;  1YIS A;  1TJ7 A;  3NO9 A;  2O7D A; 
#chains in the Genus database with same CATH topology
 1XL8 A;  5F92 A;  1Y2M A;  2K3Q A;  2HVG A;  3EZE A;  1YFM A;  2HWG A;  1SFO A;  1GKJ A;  1AUW A;  1U16 A;  3NZ4 A;  2E9F A;  3KDZ A;  3R6V A;  3CQZ A;  2AQL A;  1FUR A;  3LR2 A;  4C5R A;  3LR8 A;  2HRO A;  1EZB A;  1W27 A;  2NYN A;  3EZA A;  1XLY A;  5EYV A;  1WCM A;  2PTR A;  2RJS A;  2VSF A;  4NSL A;  1TWG A;  1XMD A;  1K62 A;  5F91 A;  1U15 A;  1GK3 A;  4EEI A;  1YNJ D;  4APA A;  1SMY D;  3CZO A;  1HY1 A;  2QVE A;  1TWH A;  4FFX A;  2X0Q A;  1TJU A;  2K3O A;  2LYI A;  2O7E A;  2LTH A;  1I3Q A;  2NYF A;  3GTL A;  3EZB A;  4FBS A;  2NVX A;  1GK2 A;  1I0A A;  3QBP A;  5D6B A;  4BAA A;  2LPI A;  2R92 A;  2FEL A;  2O7B A;  1VDK A;  1J3U A;  2YII A;  4C5S A;  1T6J A;  2VUM A;  2X0P A;  1T6P A;  2X0O A;  3R6Q A;  3CRW 1;  2FIP A;  4CEI A;  4V2R A;  3E04 A;  4EFC A;  1XL7 A;  3KDY A;  1DCN A;  1FUO A;  4WNL A;  1RE5 A;  2EZA A;  3GTM A;  1JSW A;  2E2H A;  2JA5 A;  1HY0 A;  3OCE A;  4ADM A;  2FEN A;  5M0J A;  2B63 A;  2RJR A;  1TJW A;  2VL7 A;  4APB A;  1I6V D;  1K83 A;  2F5J A;  2MX9 A;  2O6Y A;  2JA6 A;  4A15 A;  2VK9 A;  3FKI A;  1TWF A;  1FUP A;  2QGA B;  4FLC A;  2LPJ A;  4CEH A;  4BAB A;  2FUS A;  1TJV A;  1B8F A;  3OCF A;  1Q5N A;  3LRD A;  2MX8 A;  5HW2 A;  1GKM A;  4CQ5 A;  2A69 D;  2OHY A;  2K3N A;  3GTQ A;  2R7Z A;  4C2M A;  2A6E D;  2A68 D;  1IW7 D;  1TWA A;  3GTP A;  2X75 A;  2N3E A;  4ADL A;  2O78 A;  3GTK A;  4NLE A;  3TV2 A;  2MP0 A;  4CEJ A;  2O7F A;  4V2Q A;  2FIO A;  2E2I A;  4C6G A;  1EZA A;  1K7W A;  2EZB A;  2J91 A;  3CRV A;  2O5J D;  2JA7 A;  1ZYM A;  1R9T A;  1EB4 A;  1KQ7 A;  3C8T A;  1HQM D;  3H0G A;  5IZ2 A;  2MQA A;  3GTJ A;  4HGV A;  2YU9 A;  2PTQ A;  3U44 A;  1Y1W A;  3GZH A;  2CW0 D;  1YFE A;  2R93 A;  2VD6 A;  4MX2 A;  5H8W A;  2A6H D;  1XWO A;  2Y0N A;  3GTD A;  2EZC A;  1TWC A;  1YNN D;  3BHG A;  2BE5 D;  1DOF A;  4C5U A;  1C3C A;  3R6Y A;  4QIW A;  3RD8 A;  1C3U A;  2NVY A;  3U4Q A;  3GTG A;  1ZYR D;  3RRP A;  5M0I A;  2LKM B;  1XMC A;  2PFM A;  5EYT A;  2PTS A;  1FUQ A;  3UNV A;  3GTO A;  3LR6 A;  1YIS A;  1TJ7 A;  3NO9 A;  2O7D A;  1I50 A;  2N1D B;  1Y1V A; 
#chains in the Genus database with same CATH homology
 5F92 A;  1Y2M A;  2HVG A;  1YFM A;  1GKJ A;  1AUW A;  1U16 A;  3NZ4 A;  3KDZ A;  3R6V A;  2E9F A;  1FUR A;  4C5R A;  2NYN A;  1W27 A;  5EYV A;  2PTR A;  2RJS A;  4NSL A;  1K62 A;  5F91 A;  1U15 A;  1GK3 A;  4EEI A;  4APA A;  3CZO A;  1HY1 A;  2QVE A;  4FFX A;  1TJU A;  2O7E A;  2NYF A;  1I0A A;  1GK2 A;  3QBP A;  5D6B A;  4BAA A;  2O7B A;  1VDK A;  1J3U A;  2YII A;  4C5S A;  1T6J A;  1T6P A;  3R6Q A;  4V2R A;  3E04 A;  4EFC A;  3KDY A;  1DCN A;  1FUO A;  1RE5 A;  1JSW A;  1HY0 A;  3OCE A;  4ADM A;  2RJR A;  1TJW A;  4APB A;  2O6Y A;  2QGA B;  1FUP A;  4FLC A;  4BAB A;  2FUS A;  1TJV A;  1B8F A;  3OCF A;  1Q5N A;  5HW2 A;  1GKM A;  4CQ5 A;  2OHY A;  2X75 A;  4ADL A;  2O78 A;  4NLE A;  3TV2 A;  2O7F A;  4V2Q A;  4C6G A;  1K7W A;  2J91 A;  1EB4 A;  1KQ7 A;  3C8T A;  4HGV A;  4MX2 A;  2PTQ A;  3GZH A;  1YFE A;  2VD6 A;  1XWO A;  3GTD A;  3BHG A;  1DOF A;  4C5U A;  1C3C A;  3R6Y A;  3RD8 A;  1C3U A;  3RRP A;  2PFM A;  5EYT A;  2PTS A;  1FUQ A;  3UNV A;  1YIS A;  1TJ7 A;  3NO9 A;  2O7D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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