3NZ4A

Crystal structure of a taxus phenylalanine aminomutase
Total Genus 257
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
257
sequence length
670
structure length
653
Chain Sequence
SRSHVKDILGLINTFNEVKKITVDGTTPITVAHVAALARRHDVKVALEAEQCRARVETCSSWVQRKAEDGADIYGVTTGFGACSSRRTNQLSELQESLIRCLLAGVFTKGCASSVDELPATVTRSAMLLRLNSFTYGCSGIRWEVMEALEKLLNSNVSPKVPLRGSVSDLIPLAYIAGLLIGKPSVIARIGDDVEVPAPEALSRVGLRPFKLQAKEGLALVNGTSFATALASTVMYDANVLLLLVETLCGMFCEVIFGREEFAHPLIHKVKPHPGQIESAELLEWLLRSSPFQDLSREYYSIDKLKKPKQDRYALRSSPQWLAPLVQTIRDATTTVETEVNSANDNPIIDHANDRALHGANFQGSAVGFYMDYVRIAVAGLGKLLFAQFTELMIEYYSNGLPGNLSLGPDLSVDYGLKGLDIAMAAYSSELQYLANPVTTHVHSAEQHNQDINSLALISARKTDEALDILKLMIASHLTAMCQAVDLRQLEEALVKVVENVVSTLADECGLPNDTKARLLYVAKAVPVYTYLESPCDPTLPLLLGLKQSCFGSILALHKETDTLVDRLAEFEKRLSDRLENEMTAVRVLYEKVRIQGSRFLPFYRFVRDELDTGVMSARREQTPQEDVQKVFDAIADGRITVPLLHCLQGFLG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Phenylalanine ammonia-lyase
publication title Mechanistic, mutational, and structural evaluation of a taxus phenylalanine aminomutase.
pubmed doi rcsb
source organism Taxus canadensis
molecule tags Lyase
total genus 257
structure length 653
sequence length 670
chains with identical sequence B
ec nomenclature ec 4.3.1.24: Phenylalanine ammonia-lyase.
pdb deposition date 2010-07-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.20 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 Phenylalanine ammonia-lyase 1; domain 3 3nz4A03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 3nz4A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 3nz4A02
4C5UA 1T6JA 1Q5NA 2O78A 4FLCA 5EYVA 1GKJA 2PTRA 1T6PA 1DOFA 2O7DA 4MX2A 4V2RA 2OHYA 2YIIA 1B8FA 2O6YA 2X75A 4NSLA 5D6BA 3R6QA 1VDKA 4APBA 4BAAA 1AUWA 1U15A 1Y2MA 3NZ4A 2NYFA 1I0AA 1DCNA 4C5RA 4C5SA 3C8TA 1HY0A 3GZHA 1RE5A 4HGVA 4ADLA 3GTDA 4EFCA 1XWOA 1TJVA 1GK2A 2E9FA 1KQ7A 1W27A 3R6VA 3R6YA 5F91A 2QVEA 3NO9A 1K7WA 2PFMA 1FUOA 1TJ7A 3BHGA 2NYNA 1TJWA 3UNVA 2FUSA 2PTQA 4NLEA 2PTSA 2O7EA 1C3UA 2RJRA 4APAA 3OCFA 3RD8A 1GKMA 4BABA 4V2QA 2O7BA 2HVGA 3OCEA 4C6GA 1J3UA 3E04A 4FFXA 2J91A 1C3CA 1EB4A 1TJUA 3CZOA 5F92A 1YISA 4CQ5A 1FUQA 2RJSA 2VD6A 2QGAB 3KDZA 5EYTA 3TV2A 3QBPA 1YFMA 1U16A 3KDYA 4EEIA 1FURA 4ADMA 2O7FA 1JSWA 1YFEA 1GK3A 1FUPA 1K62A 5HW2A 1HY1A 3RRPA
chains in the Genus database with same CATH superfamily
4C5UA 3GTGA 1T6JA 2NVXA 1Q5NA 2O78A 4FLCA 5EYVA 2F5JA 1GKJA 2PTRA 1T6PA 3EZEA 1DOFA 2O7DA 1YNND 4MX2A 4V2RA 1WCMA 4A15A 2OHYA 2A69D 2YIIA 1B8FA 2A6HD 1I50A 2JA7A 2K3NA 2O6YA 2Y0NA 3GTLA 2X75A 2MP0A 2BE5D 2N1DB 4NSLA 1TWHA 1Y1VA 2A6ED 1EZBA 5D6BA 4QIWA 2N3EA 3R6QA 1YNJD 1VDKA 3LR8A 4APBA 3LR6A 3LRDA 4BAAA 2EZAA 1IW7D 3LR2A 2CW0D 1XLYA 1AUWA 2LPJA 1U15A 1Y2MA 3NZ4A 1SFOA 2LPIA 2NYFA 1I0AA 1DCNA 2VK9A 1XL7A 3EZAA 4C5RA 4C5SA 2MQAA 1XMCA 3GTPA 3C8TA 2HROA 1HY0A 3GTOA 1TWAA 1I6VD 3GZHA 1RE5A 4HGVA 1SMYD 2E2IA 4ADLA 1HQMD 3GTDA 4EFCA 2MX8A 5H8WA 2X0PA 2YU9A 1XWOA 2LKMB 1TJVA 1GK2A 2E9FA 1I3QA 1KQ7A 2K3QA 1W27A 1Y1WA 4CEHA 1XMDA 2VSFA 3R6VA 3GTKA 1R9TA 3R6YA 5F91A 2QVEA 3NO9A 1K7WA 1ZYMA 2PFMA 2X0QA 2FIOA 1FUOA 1TJ7A 4WNLA 3BHGA 2NYNA 3GTJA 2LYIA 1TJWA 3CRVA 2FIPA 3UNVA 3CQZA 2FUSA 2K3OA 1K83A 2PTQA 4NLEA 2PTSA 3U44A 2O7EA 1C3UA 2RJRA 2HWGA 4APAA 2NVYA 1EZAA 1TWFA 2EZBA 4CEIA 2R93A 3OCFA 3RD8A 2FELA 1GKMA 4BABA 5IZ2A 4V2QA 2B63A 1XL8A 2E2HA 1TWCA 2O7BA 4C2MA 2HVGA 3OCEA 3GTMA 4C6GA 3CRW1 1J3UA 2AQLA 2VUMA 3E04A 4FFXA 2J91A 1C3CA 1EB4A 1TJUA 3CZOA 2VL7A 5F92A 1YISA 4CQ5A 1FUQA 2RJSA 2O5JD 2JA5A 1TWGA 2QGAB 2VD6A 3KDZA 5M0IA 5EYTA 3TV2A 3QBPA 5M0JA 3H0GA 1YFMA 1U16A 2FENA 3KDYA 4EEIA 4FBSA 1ZYRD 2R7ZA 1FURA 2JA6A 4ADMA 3GTQA 3FKIA 2O7FA 1JSWA 4CEJA 1YFEA 3U4QA 1GK3A 2R92A 2X0OA 1FUPA 1K62A 5HW2A 2A68D 1HY1A 2LTHA 2MX9A 2EZCA 3RRPA 3EZBA
chains in the Genus database with same CATH topology
4C5UA 1T6JA 1Q5NA 2O78A 4FLCA 5EYVA 1GKJA 2PTRA 1T6PA 1DOFA 2O7DA 4MX2A 4V2RA 2OHYA 2YIIA 1B8FA 2O6YA 2X75A 4NSLA 5D6BA 3R6QA 1VDKA 4APBA 4BAAA 1AUWA 1U15A 1Y2MA 3NZ4A 2NYFA 1I0AA 1DCNA 4C5RA 4C5SA 3C8TA 1HY0A 3GZHA 1RE5A 4HGVA 4ADLA 3GTDA 4EFCA 1XWOA 1TJVA 1GK2A 2E9FA 1KQ7A 1W27A 3R6VA 3R6YA 5F91A 2QVEA 3NO9A 1K7WA 2PFMA 1FUOA 1TJ7A 3BHGA 2NYNA 1TJWA 3UNVA 2FUSA 2PTQA 4NLEA 2PTSA 2O7EA 1C3UA 2RJRA 4APAA 3OCFA 3RD8A 1GKMA 4BABA 4V2QA 2O7BA 2HVGA 3OCEA 4C6GA 1J3UA 3E04A 4FFXA 2J91A 1C3CA 1EB4A 1TJUA 3CZOA 5F92A 1YISA 4CQ5A 1FUQA 2RJSA 2VD6A 2QGAB 3KDZA 5EYTA 3TV2A 3QBPA 1YFMA 1U16A 3KDYA 4EEIA 1FURA 4ADMA 2O7FA 1JSWA 1YFEA 1GK3A 1FUPA 1K62A 5HW2A 1HY1A 3RRPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4C5U A;  1T6J A;  1Q5N A;  2O78 A;  4FLC A;  5EYV A;  1GKJ A;  2PTR A;  1T6P A;  1DOF A;  2O7D A;  4MX2 A;  4V2R A;  2OHY A;  2YII A;  1B8F A;  2O6Y A;  2X75 A;  4NSL A;  5D6B A;  3R6Q A;  1VDK A;  4APB A;  4BAA A;  1AUW A;  1U15 A;  1Y2M A;  3NZ4 A;  2NYF A;  1I0A A;  1DCN A;  4C5R A;  4C5S A;  3C8T A;  1HY0 A;  3GZH A;  1RE5 A;  4HGV A;  4ADL A;  3GTD A;  4EFC A;  1XWO A;  1TJV A;  1GK2 A;  2E9F A;  1KQ7 A;  1W27 A;  3R6V A;  3R6Y A;  5F91 A;  2QVE A;  3NO9 A;  1K7W A;  2PFM A;  1FUO A;  1TJ7 A;  3BHG A;  2NYN A;  1TJW A;  3UNV A;  2FUS A;  2PTQ A;  4NLE A;  2PTS A;  2O7E A;  1C3U A;  2RJR A;  4APA A;  3OCF A;  3RD8 A;  1GKM A;  4BAB A;  4V2Q A;  2O7B A;  2HVG A;  3OCE A;  4C6G A;  1J3U A;  3E04 A;  4FFX A;  2J91 A;  1C3C A;  1EB4 A;  1TJU A;  3CZO A;  5F92 A;  1YIS A;  4CQ5 A;  1FUQ A;  2RJS A;  2VD6 A;  2QGA B;  3KDZ A;  5EYT A;  3TV2 A;  3QBP A;  1YFM A;  1U16 A;  3KDY A;  4EEI A;  1FUR A;  4ADM A;  2O7F A;  1JSW A;  1YFE A;  1GK3 A;  1FUP A;  1K62 A;  5HW2 A;  1HY1 A;  3RRP A; 
#chains in the Genus database with same CATH topology
 4C5U A;  3GTG A;  1T6J A;  2NVX A;  1Q5N A;  2O78 A;  4FLC A;  5EYV A;  2F5J A;  1GKJ A;  2PTR A;  1T6P A;  3EZE A;  1DOF A;  2O7D A;  1YNN D;  4MX2 A;  4V2R A;  1WCM A;  4A15 A;  2OHY A;  2A69 D;  2YII A;  1B8F A;  2A6H D;  1I50 A;  2JA7 A;  2K3N A;  2O6Y A;  2Y0N A;  3GTL A;  2X75 A;  2MP0 A;  2BE5 D;  2N1D B;  4NSL A;  1TWH A;  1Y1V A;  2A6E D;  1EZB A;  5D6B A;  4QIW A;  2N3E A;  3R6Q A;  1YNJ D;  1VDK A;  3LR8 A;  4APB A;  3LR6 A;  3LRD A;  4BAA A;  2EZA A;  1IW7 D;  3LR2 A;  2CW0 D;  1XLY A;  1AUW A;  2LPJ A;  1U15 A;  1Y2M A;  3NZ4 A;  1SFO A;  2LPI A;  2NYF A;  1I0A A;  1DCN A;  2VK9 A;  1XL7 A;  3EZA A;  4C5R A;  4C5S A;  2MQA A;  1XMC A;  3GTP A;  3C8T A;  2HRO A;  1HY0 A;  3GTO A;  1TWA A;  1I6V D;  3GZH A;  1RE5 A;  4HGV A;  1SMY D;  2E2I A;  4ADL A;  1HQM D;  3GTD A;  4EFC A;  2MX8 A;  5H8W A;  2X0P A;  2YU9 A;  1XWO A;  2LKM B;  1TJV A;  1GK2 A;  2E9F A;  1I3Q A;  1KQ7 A;  2K3Q A;  1W27 A;  1Y1W A;  4CEH A;  1XMD A;  2VSF A;  3R6V A;  3GTK A;  1R9T A;  3R6Y A;  5F91 A;  2QVE A;  3NO9 A;  1K7W A;  1ZYM A;  2PFM A;  2X0Q A;  2FIO A;  1FUO A;  1TJ7 A;  4WNL A;  3BHG A;  2NYN A;  3GTJ A;  2LYI A;  1TJW A;  3CRV A;  2FIP A;  3UNV A;  3CQZ A;  2FUS A;  2K3O A;  1K83 A;  2PTQ A;  4NLE A;  2PTS A;  3U44 A;  2O7E A;  1C3U A;  2RJR A;  2HWG A;  4APA A;  2NVY A;  1EZA A;  1TWF A;  2EZB A;  4CEI A;  2R93 A;  3OCF A;  3RD8 A;  2FEL A;  1GKM A;  4BAB A;  5IZ2 A;  4V2Q A;  2B63 A;  1XL8 A;  2E2H A;  1TWC A;  2O7B A;  4C2M A;  2HVG A;  3OCE A;  3GTM A;  4C6G A;  3CRW 1;  1J3U A;  2AQL A;  2VUM A;  3E04 A;  4FFX A;  2J91 A;  1C3C A;  1EB4 A;  1TJU A;  3CZO A;  2VL7 A;  5F92 A;  1YIS A;  4CQ5 A;  1FUQ A;  2RJS A;  2O5J D;  2JA5 A;  1TWG A;  2QGA B;  2VD6 A;  3KDZ A;  5M0I A;  5EYT A;  3TV2 A;  3QBP A;  5M0J A;  3H0G A;  1YFM A;  1U16 A;  2FEN A;  3KDY A;  4EEI A;  4FBS A;  1ZYR D;  2R7Z A;  1FUR A;  2JA6 A;  4ADM A;  3GTQ A;  3FKI A;  2O7F A;  1JSW A;  4CEJ A;  1YFE A;  3U4Q A;  1GK3 A;  2R92 A;  2X0O A;  1FUP A;  1K62 A;  5HW2 A;  2A68 D;  1HY1 A;  2LTH A;  2MX9 A;  2EZC A;  3RRP A;  3EZB A; 
#chains in the Genus database with same CATH homology
 4C5U A;  1T6J A;  1Q5N A;  2O78 A;  4FLC A;  5EYV A;  1GKJ A;  2PTR A;  1T6P A;  1DOF A;  2O7D A;  4MX2 A;  4V2R A;  2OHY A;  2YII A;  1B8F A;  2O6Y A;  2X75 A;  4NSL A;  5D6B A;  3R6Q A;  1VDK A;  4APB A;  4BAA A;  1AUW A;  1U15 A;  1Y2M A;  3NZ4 A;  2NYF A;  1I0A A;  1DCN A;  4C5R A;  4C5S A;  3C8T A;  1HY0 A;  3GZH A;  1RE5 A;  4HGV A;  4ADL A;  3GTD A;  4EFC A;  1XWO A;  1TJV A;  1GK2 A;  2E9F A;  1KQ7 A;  1W27 A;  3R6V A;  3R6Y A;  5F91 A;  2QVE A;  3NO9 A;  1K7W A;  2PFM A;  1FUO A;  1TJ7 A;  3BHG A;  2NYN A;  1TJW A;  3UNV A;  2FUS A;  2PTQ A;  4NLE A;  2PTS A;  2O7E A;  1C3U A;  2RJR A;  4APA A;  3OCF A;  3RD8 A;  1GKM A;  4BAB A;  4V2Q A;  2O7B A;  2HVG A;  3OCE A;  4C6G A;  1J3U A;  3E04 A;  4FFX A;  2J91 A;  1C3C A;  1EB4 A;  1TJU A;  3CZO A;  5F92 A;  1YIS A;  4CQ5 A;  1FUQ A;  2RJS A;  2VD6 A;  2QGA B;  3KDZ A;  5EYT A;  3TV2 A;  3QBP A;  1YFM A;  1U16 A;  3KDY A;  4EEI A;  1FUR A;  4ADM A;  2O7F A;  1JSW A;  1YFE A;  1GK3 A;  1FUP A;  1K62 A;  5HW2 A;  1HY1 A;  3RRP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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