2EZCA

Amino terminal domain of enzyme i from escherichia coli, nmr, 14 structures
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
249
structure length
249
Chain Sequence
MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRAVQEQVASE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Phosphotransferase
molecule keywords PHOSPHOTRANSFERASE SYSTEM, ENZYME I
publication title Defining long range order in NMR structure determination from the dependence of heteronuclear relaxation times on rotational diffusion anisotropy.
pubmed doi rcsb
source organism Escherichia coli
total genus 71
structure length 249
sequence length 249
ec nomenclature ec 2.7.3.9: Phosphoenolpyruvate--protein phosphotransferase.
pdb deposition date 1997-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00391 PEP-utilizers PEP-utilising enzyme, mobile domain
A PF05524 PEP-utilisers_N PEP-utilising enzyme, N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.10 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 PtsI, HPr-binding domain 2ezcA02
3.50.30.10 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Phosphohistidine domain 2ezcA01
3T0TA 1GGOA 1JDEA 1KBLA 2HWGA 5JVLA 1EZAA 2X0SA 3T05A 2DIKA 1VBHA 2OLSA 2MP0A 2EZAA 1KC7A 3EZEA 3EZBA 1DIKA 2FM4A 2EZBA 2HI6A 2R82A 1ZYMA 1VBGA 3EZAA 2EZCA 2E28A 3T07A 2HROA 1EZBA
chains in the Genus database with same CATH superfamily
2LKMB 5K99A 3U44A 4FBSA 4BAAA 2EK8A 2K3QA 2HWGA 2C6GA 4CDKA 2N3EA 4JYWA 2E2IA 1Y9ZA 4C8PA 1DIKA 3BI1A 4JVOA 4IIYA 2NVXA 2D0PA 3GTJA 4C85A 1Y1VA 3S9NA 3EIFA 1XF1A 2LTHA 1Z8LA 1YNND 1V6CA 3TLCA 4KNGE 2FIPA 2HROA 4CEHA 1EZBA 2LPIA 4C8CA 2F5JA 2VUMA 4V2RA 3IIBA 2FIOA 2BE5D 2AUNA 4NGNA 3TLZA 3TLEA 4CDJA 3GTPA 1GGOA 3BI0A 3S9LA 1KBLA 4C9AA 3BXMA 1HQMD 3CQZA 1DE4C 2X0SA 2YIIA 3ICUA 1YNJD 4QIWA 3EZEA 2X0QA 1I3QA 5F09A 1TWGA 1M6VB 4MI1A 3D7GA 4C9UA 2PVWA 2DIKA 3FECA 4CEJA 2PVVA 5FD8A 4C8UA 1VI4A 3SJGA 4W9YA 4TJVA 4EYSA 4E5SA 4NGPA 2K3OA 2B0AA 4P4FA 2X0OA 2MX8A 3NZ4A 2R93A 4C99A 4MCPA 3KRVA 2C5QA 2A6ED 1NBWA 3SJEA 4C9RA 1JDBC 3TLBA 2MP0A 4NGTA 3GTLA 2EZCA 1TWFA 4COBA 3T0TA 2A68D 2C6CA 3BHXA 1IW7D 1I6VD 3TYXA 1EZAA 3S9MA 5IZ2A 1W27A 4P4EA 2B63A 4E94A 2E2HA 2FM4A 5ELYA 4X3RA 1ZYRD 1ZYMA 2LPJA 2LYIA 4J0NA 1Y1WA 4P4BA 4LQGA 3TLGB 2MQAA 4V2QA 4NGQA 2CW0D 4CQ5A 4P4IA 3C8OA 3LR8A 1CS0B 2JA6A 1BXRB 5F9MA 3GTQA 3TLAA 1T6PA 3SJXA 3FEDA 3GTGA 2YJTA 5IB9A 3K4IA 4C86A 1I50A 1T6JA 2AUMA 2JBJA 1K83A 3IWWA 1Q5XA 3GTOA 4C5UA 1C3OB 2AQLA 1NXJA 2VK9A 3I74A 2R82A 3GJZA 1J3LA 4C5SA 4C5RA 1KEEB 1SFOA 3T5MA 1WVMA 1CE8B 3D7DA 4MJXA 2E28A 3T07A 3GTKA 3U1BA 4NGMA 4C84A 2A6HD 4BABA 3RBUA 2K3NA 5JVLA 1Y2MA 3TLYA 2YU9A 4C8AA 2N1DB 2R92A 2OR4A 2EK9A 5F1YA 5F5XA 2JBKA 3SJFA 3LR2A 2O5JD 2OOTA 4IIXA 2XEJA 4YN3A 4NGRA 1JDEA 4P4DA 1CX8A 4TJXA 4C6GA 4C8TA 4MCQA 3H0GA 3T05A 2PCNA 3I6SA 3FF3A 4M8DA 3K9TA 4H1HA 1R9TA 1TWCA 3EZAA 4INJA 3LR6A 2JA7A 1VBHA 2OLSA 4P45A 2EZAA 1WCMA 2XEGA 3D7FA 1TWAA 1R61A 1KC7A 2R7ZA 3U4QA 2MX9A 4NGSA 2NVYA 4OC4A 4C9EA 2XEIA 3VTAA 3GTMA 4C2MA 2CIJA 1A9XB 3FEEA 2X0PA 1VBGA 4CO9A 3SR3A 4P44A 3D7HA 1ZL0A 4CZ1A 4OC5A 4MCSA 1SMYD 3NOJA 2A69D 1C30B 4TWEA 4COGA 4JZ0A 2C6PA 4OC2A 1TWHA 2D0OA 4OMEA 4C8FA 4CEIA 1ZRSA 5JYBA 3FKIA 2Y0NA 3G23A 4C9VA 4OC3A 3KASA 4MCRA 5IR2A 3LRDA 2GP4A 2XEFA 4P4JA 2YJVA 4OC1A 3EZBA 2EZBA 2HI6A 5D29A 2JA5A 1T36B 4OC0A 3TLGA
chains in the Genus database with same CATH topology
3T0TA 1GGOA 1JDEA 1KBLA 2HWGA 5JVLA 1EZAA 2X0SA 3T05A 2DIKA 1VBHA 2OLSA 2MP0A 2EZAA 1KC7A 3EZEA 3EZBA 1DIKA 2FM4A 2EZBA 2HI6A 2R82A 1ZYMA 1VBGA 3EZAA 2EZCA 2E28A 3T07A 2HROA 1EZBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3T0T A;  1GGO A;  1JDE A;  1KBL A;  2HWG A;  5JVL A;  1EZA A;  2X0S A;  3T05 A;  2DIK A;  1VBH A;  2OLS A;  2MP0 A;  2EZA A;  1KC7 A;  3EZE A;  3EZB A;  1DIK A;  2FM4 A;  2EZB A;  2HI6 A;  2R82 A;  1ZYM A;  1VBG A;  3EZA A;  2EZC A;  2E28 A;  3T07 A;  2HRO A;  1EZB A; 
#chains in the Genus database with same CATH topology
 2LKM B;  5K99 A;  3U44 A;  4FBS A;  4BAA A;  2EK8 A;  2K3Q A;  2HWG A;  2C6G A;  4CDK A;  2N3E A;  4JYW A;  2E2I A;  1Y9Z A;  4C8P A;  1DIK A;  3BI1 A;  4JVO A;  4IIY A;  2NVX A;  2D0P A;  3GTJ A;  4C85 A;  1Y1V A;  3S9N A;  3EIF A;  1XF1 A;  2LTH A;  1Z8L A;  1YNN D;  1V6C A;  3TLC A;  4KNG E;  2FIP A;  2HRO A;  4CEH A;  1EZB A;  2LPI A;  4C8C A;  2F5J A;  2VUM A;  4V2R A;  3IIB A;  2FIO A;  2BE5 D;  2AUN A;  4NGN A;  3TLZ A;  3TLE A;  4CDJ A;  3GTP A;  1GGO A;  3BI0 A;  3S9L A;  1KBL A;  4C9A A;  3BXM A;  1HQM D;  3CQZ A;  1DE4 C;  2X0S A;  2YII A;  3ICU A;  1YNJ D;  4QIW A;  3EZE A;  2X0Q A;  1I3Q A;  5F09 A;  1TWG A;  1M6V B;  4MI1 A;  3D7G A;  4C9U A;  2PVW A;  2DIK A;  3FEC A;  4CEJ A;  2PVV A;  5FD8 A;  4C8U A;  1VI4 A;  3SJG A;  4W9Y A;  4TJV A;  4EYS A;  4E5S A;  4NGP A;  2K3O A;  2B0A A;  4P4F A;  2X0O A;  2MX8 A;  3NZ4 A;  2R93 A;  4C99 A;  4MCP A;  3KRV A;  2C5Q A;  2A6E D;  1NBW A;  3SJE A;  4C9R A;  1JDB C;  3TLB A;  2MP0 A;  4NGT A;  3GTL A;  2EZC A;  1TWF A;  4COB A;  3T0T A;  2A68 D;  2C6C A;  3BHX A;  1IW7 D;  1I6V D;  3TYX A;  1EZA A;  3S9M A;  5IZ2 A;  1W27 A;  4P4E A;  2B63 A;  4E94 A;  2E2H A;  2FM4 A;  5ELY A;  4X3R A;  1ZYR D;  1ZYM A;  2LPJ A;  2LYI A;  4J0N A;  1Y1W A;  4P4B A;  4LQG A;  3TLG B;  2MQA A;  4V2Q A;  4NGQ A;  2CW0 D;  4CQ5 A;  4P4I A;  3C8O A;  3LR8 A;  1CS0 B;  2JA6 A;  1BXR B;  5F9M A;  3GTQ A;  3TLA A;  1T6P A;  3SJX A;  3FED A;  3GTG A;  2YJT A;  5IB9 A;  3K4I A;  4C86 A;  1I50 A;  1T6J A;  2AUM A;  2JBJ A;  1K83 A;  3IWW A;  1Q5X A;  3GTO A;  4C5U A;  1C3O B;  2AQL A;  1NXJ A;  2VK9 A;  3I74 A;  2R82 A;  3GJZ A;  1J3L A;  4C5S A;  4C5R A;  1KEE B;  1SFO A;  3T5M A;  1WVM A;  1CE8 B;  3D7D A;  4MJX A;  2E28 A;  3T07 A;  3GTK A;  3U1B A;  4NGM A;  4C84 A;  2A6H D;  4BAB A;  3RBU A;  2K3N A;  5JVL A;  1Y2M A;  3TLY A;  2YU9 A;  4C8A A;  2N1D B;  2R92 A;  2OR4 A;  2EK9 A;  5F1Y A;  5F5X A;  2JBK A;  3SJF A;  3LR2 A;  2O5J D;  2OOT A;  4IIX A;  2XEJ A;  4YN3 A;  4NGR A;  1JDE A;  4P4D A;  1CX8 A;  4TJX A;  4C6G A;  4C8T A;  4MCQ A;  3H0G A;  3T05 A;  2PCN A;  3I6S A;  3FF3 A;  4M8D A;  3K9T A;  4H1H A;  1R9T A;  1TWC A;  3EZA A;  4INJ A;  3LR6 A;  2JA7 A;  1VBH A;  2OLS A;  4P45 A;  2EZA A;  1WCM A;  2XEG A;  3D7F A;  1TWA A;  1R61 A;  1KC7 A;  2R7Z A;  3U4Q A;  2MX9 A;  4NGS A;  2NVY A;  4OC4 A;  4C9E A;  2XEI A;  3VTA A;  3GTM A;  4C2M A;  2CIJ A;  1A9X B;  3FEE A;  2X0P A;  1VBG A;  4CO9 A;  3SR3 A;  4P44 A;  3D7H A;  1ZL0 A;  4CZ1 A;  4OC5 A;  4MCS A;  1SMY D;  3NOJ A;  2A69 D;  1C30 B;  4TWE A;  4COG A;  4JZ0 A;  2C6P A;  4OC2 A;  1TWH A;  2D0O A;  4OME A;  4C8F A;  4CEI A;  1ZRS A;  5JYB A;  3FKI A;  2Y0N A;  3G23 A;  4C9V A;  4OC3 A;  3KAS A;  4MCR A;  5IR2 A;  3LRD A;  2GP4 A;  2XEF A;  4P4J A;  2YJV A;  4OC1 A;  3EZB A;  2EZB A;  2HI6 A;  5D29 A;  2JA5 A;  1T36 B;  4OC0 A;  3TLG A; 
#chains in the Genus database with same CATH homology
 3T0T A;  1GGO A;  1JDE A;  1KBL A;  2HWG A;  5JVL A;  1EZA A;  2X0S A;  3T05 A;  2DIK A;  1VBH A;  2OLS A;  2MP0 A;  2EZA A;  1KC7 A;  3EZE A;  3EZB A;  1DIK A;  2FM4 A;  2EZB A;  2HI6 A;  2R82 A;  1ZYM A;  1VBG A;  3EZA A;  2EZC A;  2E28 A;  3T07 A;  2HRO A;  1EZB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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