2EZCA

Amino terminal domain of enzyme i from escherichia coli, nmr, 14 structures
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
249
structure length
249
Chain Sequence
b'MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRAVQEQVASE'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords PHOSPHOTRANSFERASE SYSTEM, ENZYME I
publication title Defining long range order in NMR structure determination from the dependence of heteronuclear relaxation times on rotational diffusion anisotropy.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Phosphotransferase
total genus 71
structure length 249
sequence length 249
ec nomenclature ec 2.7.3.9: Phosphoenolpyruvate--protein phosphotransferase.
pdb deposition date 1997-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00391 PEP-utilizers PEP-utilising enzyme, mobile domain
A PF05524 PEP-utilisers_N PEP-utilising enzyme, N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.10 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 PtsI, HPr-binding domain 2ezcA02
3.50.30.10 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Phosphohistidine domain 2ezcA01
2EZBA 3T05A 3EZAA 1DIKA 5JVLA 1EZBA 3T07A 2HI6A 1VBHA 1GGOA 2R82A 2DIKA 2E28A 2MP0A 1JDEA 2EZAA 2X0SA 2EZCA 1VBGA 2HWGA 1KC7A 2FM4A 1ZYMA 3EZBA 3EZEA 2OLSA 1KBLA 3T0TA 2HROA 1EZAA
chains in the Genus database with same CATH superfamily
2A69D 4X3RA 1TWFA 4LQGA 2JBJA 3TLEA 2A68D 2C6GA 4C99A 3GTGA 4C8TA 3FKIA 3RBUA 4CQ5A 2MP0A 2A6ED 4MI1A 1KC7A 1ZYMA 1KBLA 2AUNA 1ZRSA 2E2HA 1TWAA 3D7FA 4MCQA 2HI6A 2K3OA 2NVXA 4CDJA 2JA7A 3FEEA 3NZ4A 4TJXA 2K3NA 4M8DA 2F5JA 3K4IA 3U1BA 4CZ1A 2X0OA 2EZCA 4P4IA 4C85A 4C8FA 4P4FA 2C5QA 3TLBA 2FM4A 2LTHA 5F09A 4OMEA 3TLGB 2PCNA 3TYXA 3SR3A 1C30B 1DIKA 2FIPA 2MQAA 4FBSA 2EK8A 4P44A 1T6PA 2AQLA 4NGSA 2CW0D 3GTLA 3EZEA 1Q5XA 2LPJA 2XEGA 5FD8A 4IIXA 4C9EA 2E2IA 3T07A 2BE5D 4EYSA 3FF3A 1BXRB 5F1YA 2E28A 4OC1A 2B0AA 2VK9A 4V2RA 1VBGA 1TWCA 4C8PA 3CQZA 3D7DA 4KNGE 2OLSA 3S9MA 2R7ZA 2GP4A 2EZBA 1CS0B 1WCMA 3H0GA 1HQMD 2NVYA 4J0NA 4CEIA 4C2MA 3S9LA 4MCRA 4COGA 1TWGA 3GTOA 1YNJD 3EZAA 3GTPA 5ELYA 1Y1VA 4E94A 4CEJA 2LYIA 2PVWA 3D7GA 1ZL0A 2XEIA 4CDKA 1I6VD 3FECA 3GTMA 1EZAA 4P45A 3TLYA 3T05A 1JDBC 3BI1A 3FEDA 1IW7D 2X0QA 4CO9A 1Y1WA 2JA5A 3D7HA 1JDEA 1CE8B 4CEHA 4JZ0A 2OOTA 2A6HD 4P4JA 4TWEA 5D29A 3C8OA 2FIOA 2JA6A 1I3QA 4MJXA 4NGNA 4MCPA 1WVMA 3LR2A 1A9XB 2XEFA 4C6GA 2EK9A 4BABA 4NGRA 4C8AA 2N3EA 4OC3A 4C9VA 3S9NA 1R9TA 4TJVA 1XF1A 2X0PA 1VBHA 1SFOA 3LR6A 3IWWA 2X0SA 5F9MA 2JBKA 3SJXA 1ZYRD 2MX9A 5IZ2A 4P4BA 2C6PA 3T5MA 2CIJA 4E5SA 4YN3A 4C86A 2MX8A 1NXJA 2YJVA 4QIWA 1TWHA 1C3OB 1Y9ZA 3EIFA 3K9TA 2HWGA 1SMYD 3EZBA 5IB9A 3SJGA 5JVLA 3I6SA 3ICUA 1Y2MA 4W9YA 2LPIA 1YNND 4C84A 4C8CA 1EZBA 1J3LA 3GTJA 1CX8A 4COBA 4NGPA 2DIKA 4C9AA 1NBWA 4INJA 5K99A 3KASA 4C5UA 1DE4C 2N1DB 2AUMA 4NGTA 3KRVA 2OR4A 2PVVA 3BI0A 2YJTA 2D0OA 4V2QA 5JYBA 4C9RA 4OC4A 2XEJA 2LKMB 3GJZA 1Z8LA 3SJFA 4BAAA 4NGMA 3T0TA 4C9UA 1W27A 2VUMA 3SJEA 3U44A 2YIIA 4C5SA 1GGOA 4NGQA 3TLAA 2B63A 4MCSA 2Y0NA 3LRDA 4C5RA 2R93A 2HROA 4JVOA 3BHXA 3TLZA 3U4QA 4C8UA 1M6VB 3VTAA 2D0PA 4JYWA 3TLGA 2K3QA 3GTQA 4OC2A 1V6CA 1I50A 2EZAA 3BXMA 1R61A 3LR8A 1KEEB 1K83A 4OC0A 3NOJA 4IIYA 2YU9A 1T36B 3GTKA 3TLCA 2C6CA 4P4EA 2R82A 1VI4A 3I74A 5F5XA 5IR2A 1T6JA 4H1HA 2R92A 2O5JD 4P4DA 3IIBA 3G23A 4OC5A
chains in the Genus database with same CATH topology
2EZBA 3T05A 3EZAA 1DIKA 5JVLA 1EZBA 3T07A 2HI6A 1VBHA 1GGOA 2R82A 2DIKA 2E28A 2MP0A 1JDEA 2EZAA 2X0SA 2EZCA 1VBGA 2HWGA 1KC7A 2FM4A 1ZYMA 3EZBA 3EZEA 2OLSA 1KBLA 3T0TA 2HROA 1EZAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EZB A;  3T05 A;  3EZA A;  1DIK A;  5JVL A;  1EZB A;  3T07 A;  2HI6 A;  1VBH A;  1GGO A;  2R82 A;  2DIK A;  2E28 A;  2MP0 A;  1JDE A;  2EZA A;  2X0S A;  2EZC A;  1VBG A;  2HWG A;  1KC7 A;  2FM4 A;  1ZYM A;  3EZB A;  3EZE A;  2OLS A;  1KBL A;  3T0T A;  2HRO A;  1EZA A; 
#chains in the Genus database with same CATH topology
 2A69 D;  4X3R A;  1TWF A;  4LQG A;  2JBJ A;  3TLE A;  2A68 D;  2C6G A;  4C99 A;  3GTG A;  4C8T A;  3FKI A;  3RBU A;  4CQ5 A;  2MP0 A;  2A6E D;  4MI1 A;  1KC7 A;  1ZYM A;  1KBL A;  2AUN A;  1ZRS A;  2E2H A;  1TWA A;  3D7F A;  4MCQ A;  2HI6 A;  2K3O A;  2NVX A;  4CDJ A;  2JA7 A;  3FEE A;  3NZ4 A;  4TJX A;  2K3N A;  4M8D A;  2F5J A;  3K4I A;  3U1B A;  4CZ1 A;  2X0O A;  2EZC A;  4P4I A;  4C85 A;  4C8F A;  4P4F A;  2C5Q A;  3TLB A;  2FM4 A;  2LTH A;  5F09 A;  4OME A;  3TLG B;  2PCN A;  3TYX A;  3SR3 A;  1C30 B;  1DIK A;  2FIP A;  2MQA A;  4FBS A;  2EK8 A;  4P44 A;  1T6P A;  2AQL A;  4NGS A;  2CW0 D;  3GTL A;  3EZE A;  1Q5X A;  2LPJ A;  2XEG A;  5FD8 A;  4IIX A;  4C9E A;  2E2I A;  3T07 A;  2BE5 D;  4EYS A;  3FF3 A;  1BXR B;  5F1Y A;  2E28 A;  4OC1 A;  2B0A A;  2VK9 A;  4V2R A;  1VBG A;  1TWC A;  4C8P A;  3CQZ A;  3D7D A;  4KNG E;  2OLS A;  3S9M A;  2R7Z A;  2GP4 A;  2EZB A;  1CS0 B;  1WCM A;  3H0G A;  1HQM D;  2NVY A;  4J0N A;  4CEI A;  4C2M A;  3S9L A;  4MCR A;  4COG A;  1TWG A;  3GTO A;  1YNJ D;  3EZA A;  3GTP A;  5ELY A;  1Y1V A;  4E94 A;  4CEJ A;  2LYI A;  2PVW A;  3D7G A;  1ZL0 A;  2XEI A;  4CDK A;  1I6V D;  3FEC A;  3GTM A;  1EZA A;  4P45 A;  3TLY A;  3T05 A;  1JDB C;  3BI1 A;  3FED A;  1IW7 D;  2X0Q A;  4CO9 A;  1Y1W A;  2JA5 A;  3D7H A;  1JDE A;  1CE8 B;  4CEH A;  4JZ0 A;  2OOT A;  2A6H D;  4P4J A;  4TWE A;  5D29 A;  3C8O A;  2FIO A;  2JA6 A;  1I3Q A;  4MJX A;  4NGN A;  4MCP A;  1WVM A;  3LR2 A;  1A9X B;  2XEF A;  4C6G A;  2EK9 A;  4BAB A;  4NGR A;  4C8A A;  2N3E A;  4OC3 A;  4C9V A;  3S9N A;  1R9T A;  4TJV A;  1XF1 A;  2X0P A;  1VBH A;  1SFO A;  3LR6 A;  3IWW A;  2X0S A;  5F9M A;  2JBK A;  3SJX A;  1ZYR D;  2MX9 A;  5IZ2 A;  4P4B A;  2C6P A;  3T5M A;  2CIJ A;  4E5S A;  4YN3 A;  4C86 A;  2MX8 A;  1NXJ A;  2YJV A;  4QIW A;  1TWH A;  1C3O B;  1Y9Z A;  3EIF A;  3K9T A;  2HWG A;  1SMY D;  3EZB A;  5IB9 A;  3SJG A;  5JVL A;  3I6S A;  3ICU A;  1Y2M A;  4W9Y A;  2LPI A;  1YNN D;  4C84 A;  4C8C A;  1EZB A;  1J3L A;  3GTJ A;  1CX8 A;  4COB A;  4NGP A;  2DIK A;  4C9A A;  1NBW A;  4INJ A;  5K99 A;  3KAS A;  4C5U A;  1DE4 C;  2N1D B;  2AUM A;  4NGT A;  3KRV A;  2OR4 A;  2PVV A;  3BI0 A;  2YJT A;  2D0O A;  4V2Q A;  5JYB A;  4C9R A;  4OC4 A;  2XEJ A;  2LKM B;  3GJZ A;  1Z8L A;  3SJF A;  4BAA A;  4NGM A;  3T0T A;  4C9U A;  1W27 A;  2VUM A;  3SJE A;  3U44 A;  2YII A;  4C5S A;  1GGO A;  4NGQ A;  3TLA A;  2B63 A;  4MCS A;  2Y0N A;  3LRD A;  4C5R A;  2R93 A;  2HRO A;  4JVO A;  3BHX A;  3TLZ A;  3U4Q A;  4C8U A;  1M6V B;  3VTA A;  2D0P A;  4JYW A;  3TLG A;  2K3Q A;  3GTQ A;  4OC2 A;  1V6C A;  1I50 A;  2EZA A;  3BXM A;  1R61 A;  3LR8 A;  1KEE B;  1K83 A;  4OC0 A;  3NOJ A;  4IIY A;  2YU9 A;  1T36 B;  3GTK A;  3TLC A;  2C6C A;  4P4E A;  2R82 A;  1VI4 A;  3I74 A;  5F5X A;  5IR2 A;  1T6J A;  4H1H A;  2R92 A;  2O5J D;  4P4D A;  3IIB A;  3G23 A;  4OC5 A; 
#chains in the Genus database with same CATH homology
 2EZB A;  3T05 A;  3EZA A;  1DIK A;  5JVL A;  1EZB A;  3T07 A;  2HI6 A;  1VBH A;  1GGO A;  2R82 A;  2DIK A;  2E28 A;  2MP0 A;  1JDE A;  2EZA A;  2X0S A;  2EZC A;  1VBG A;  2HWG A;  1KC7 A;  2FM4 A;  1ZYM A;  3EZB A;  3EZE A;  2OLS A;  1KBL A;  3T0T A;  2HRO A;  1EZA A; 
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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