2EZCA

Amino terminal domain of enzyme i from escherichia coli, nmr, 14 structures
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
249
structure length
249
Chain Sequence
MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRAVQEQVASE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Defining long range order in NMR structure determination from the dependence of heteronuclear relaxation times on rotational diffusion anisotropy.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Phosphotransferase
molecule keywords PHOSPHOTRANSFERASE SYSTEM, ENZYME I
total genus 71
structure length 249
sequence length 249
ec nomenclature ec 2.7.3.9: Phosphoenolpyruvate--protein phosphotransferase.
pdb deposition date 1997-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00391 PEP-utilizers PEP-utilising enzyme, mobile domain
A PF05524 PEP-utilisers_N PEP-utilising enzyme, N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.10 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 PtsI, HPr-binding domain 2ezcA02
3.50.30.10 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Phosphohistidine domain 2ezcA01
1EZBA 2HWGA 2OLSA 2X0SA 3T05A 3EZEA 2EZBA 2EZAA 3EZBA 5JVLA 1KBLA 1VBGA 2E28A 3EZAA 2EZCA 2R82A 2HROA 1VBHA 3T07A 1DIKA 2HI6A 1GGOA 1EZAA 1ZYMA 2FM4A 3T0TA 1JDEA 1KC7A 2DIKA 2MP0A
chains in the Genus database with same CATH superfamily
2CW0D 4BABA 1EZBA 3D7GA 4OC2A 2XEJA 2JA6A 2B0AA 3TLZA 4INJA 3FEEA 1YNND 1V6CA 3T05A 4C9EA 2NVYA 2BE5D 4OC0A 4TWEA 3D7HA 3D7DA 4C86A 4C8TA 3I6SA 4TJVA 5ELYA 3ICUA 2AUMA 2F5JA 4C2MA 1KBLA 2JBJA 5K99A 2E2HA 3LR6A 2PCNA 4C9UA 4CEJA 2CIJA 4MJXA 4MCQA 4OC1A 4P4BA 4OC5A 5D29A 1DIKA 1Y1WA 2D0OA 3GTOA 2A6HD 3U44A 2MX8A 3BI0A 2K3QA 1WVMA 4M8DA 5F9MA 4C85A 2O5JD 2PVVA 1HQMD 1TWCA 4CDJA 3D7FA 1ZRSA 2E2IA 2FM4A 3K9TA 4KNGE 5FD8A 3T0TA 4CEIA 1XF1A 4C9RA 4P4IA 2YJVA 3C8OA 1KC7A 1YNJD 4TJXA 4C99A 2A68D 3T5MA 3TYXA 3GTMA 4NGSA 2OLSA 2X0SA 2PVWA 2GP4A 2XEFA 2N1DB 1IW7D 4NGTA 3S9MA 1NXJA 3IIBA 4BAAA 3SJEA 2R93A 4LQGA 2EZBA 3KRVA 4JYWA 3EZBA 4NGRA 3SJFA 4OC4A 3NZ4A 1VBGA 2C6PA 2E28A 3GTLA 3G23A 4MCRA 3TLGB 3GTKA 1Y9ZA 1M6VB 3FF3A 3S9LA 2MX9A 1A9XB 2HROA 1VBHA 4NGPA 3GTGA 3EIFA 1Q5XA 2OOTA 3SJGA 4MI1A 3TLEA 1EZAA 4P4FA 4C8CA 3BHXA 2YU9A 4J0NA 3SJXA 2LPIA 4MCSA 2LTHA 3IWWA 4COBA 1TWHA 4V2RA 1NBWA 1ZL0A 2YIIA 2DIKA 1SMYD 3LRDA 2C6GA 2X0PA 2HWGA 1J3LA 3BI1A 3U4QA 3K4IA 2Y0NA 1TWAA 3FKIA 4IIXA 1I6VD 4QIWA 3CQZA 4P4JA 4W9YA 4YN3A 2A69D 4CQ5A 1VI4A 3TLGA 4C8AA 1DE4C 2EK8A 4NGQA 2A6ED 2OR4A 3KASA 3U1BA 2EZAA 3GJZA 1Y2MA 5JVLA 4C5RA 3VTAA 1R9TA 2VK9A 5F1YA 2FIOA 4NGMA 5IB9A 4COGA 4C8PA 2HI6A 2XEGA 3GTPA 2JA5A 3NOJA 3SR3A 3BXMA 4FBSA 3FEDA 2JA7A 3H0GA 5F5XA 1GGOA 3TLBA 2R7ZA 4CO9A 1T36B 1ZYMA 1K83A 4P44A 1ZYRD 4JVOA 4CEHA 2R92A 1JDBC 4P4EA 3RBUA 2X0OA 4EYSA 1JDEA 4OMEA 4V2QA 2LKMB 4MCPA 2MQAA 4OC3A 2B63A 1T6JA 2C6CA 1CX8A 3T07A 2N3EA 4C8FA 4IIYA 1T6PA 1SFOA 4JZ0A 2NVXA 1C3OB 1TWFA 3S9NA 3LR2A 2AUNA 3FECA 3EZEA 4C6GA 1Z8LA 3TLCA 1CS0B 2MP0A 1CE8B 1KEEB 2FIPA 4P4DA 4H1HA 3TLYA 2VUMA 1BXRB 4C9VA 2EK9A 3EZAA 4CZ1A 2X0QA 2C5QA 3I74A 1TWGA 5IR2A 5F09A 2EZCA 2R82A 3TLAA 4E5SA 2YJTA 1W27A 2LYIA 1I50A 3GTQA 4C5UA 3GTJA 1WCMA 4X3RA 5IZ2A 4C5SA 2JBKA 2K3NA 4C84A 2K3OA 2AQLA 1I3QA 2D0PA 4C8UA 5JYBA 4CDKA 4P45A 4NGNA 1R61A 2LPJA 4C9AA 1Y1VA 2XEIA 4E94A 1C30B 3LR8A
chains in the Genus database with same CATH topology
1EZBA 2HWGA 2OLSA 2X0SA 3T05A 3EZEA 2EZBA 2EZAA 3EZBA 5JVLA 1KBLA 1VBGA 2E28A 3EZAA 2EZCA 2R82A 2HROA 1VBHA 3T07A 1DIKA 2HI6A 1GGOA 1EZAA 1ZYMA 2FM4A 3T0TA 1JDEA 1KC7A 2DIKA 2MP0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EZB A;  2HWG A;  2OLS A;  2X0S A;  3T05 A;  3EZE A;  2EZB A;  2EZA A;  3EZB A;  5JVL A;  1KBL A;  1VBG A;  2E28 A;  3EZA A;  2EZC A;  2R82 A;  2HRO A;  1VBH A;  3T07 A;  1DIK A;  2HI6 A;  1GGO A;  1EZA A;  1ZYM A;  2FM4 A;  3T0T A;  1JDE A;  1KC7 A;  2DIK A;  2MP0 A; 
#chains in the Genus database with same CATH topology
 2CW0 D;  4BAB A;  1EZB A;  3D7G A;  4OC2 A;  2XEJ A;  2JA6 A;  2B0A A;  3TLZ A;  4INJ A;  3FEE A;  1YNN D;  1V6C A;  3T05 A;  4C9E A;  2NVY A;  2BE5 D;  4OC0 A;  4TWE A;  3D7H A;  3D7D A;  4C86 A;  4C8T A;  3I6S A;  4TJV A;  5ELY A;  3ICU A;  2AUM A;  2F5J A;  4C2M A;  1KBL A;  2JBJ A;  5K99 A;  2E2H A;  3LR6 A;  2PCN A;  4C9U A;  4CEJ A;  2CIJ A;  4MJX A;  4MCQ A;  4OC1 A;  4P4B A;  4OC5 A;  5D29 A;  1DIK A;  1Y1W A;  2D0O A;  3GTO A;  2A6H D;  3U44 A;  2MX8 A;  3BI0 A;  2K3Q A;  1WVM A;  4M8D A;  5F9M A;  4C85 A;  2O5J D;  2PVV A;  1HQM D;  1TWC A;  4CDJ A;  3D7F A;  1ZRS A;  2E2I A;  2FM4 A;  3K9T A;  4KNG E;  5FD8 A;  3T0T A;  4CEI A;  1XF1 A;  4C9R A;  4P4I A;  2YJV A;  3C8O A;  1KC7 A;  1YNJ D;  4TJX A;  4C99 A;  2A68 D;  3T5M A;  3TYX A;  3GTM A;  4NGS A;  2OLS A;  2X0S A;  2PVW A;  2GP4 A;  2XEF A;  2N1D B;  1IW7 D;  4NGT A;  3S9M A;  1NXJ A;  3IIB A;  4BAA A;  3SJE A;  2R93 A;  4LQG A;  2EZB A;  3KRV A;  4JYW A;  3EZB A;  4NGR A;  3SJF A;  4OC4 A;  3NZ4 A;  1VBG A;  2C6P A;  2E28 A;  3GTL A;  3G23 A;  4MCR A;  3TLG B;  3GTK A;  1Y9Z A;  1M6V B;  3FF3 A;  3S9L A;  2MX9 A;  1A9X B;  2HRO A;  1VBH A;  4NGP A;  3GTG A;  3EIF A;  1Q5X A;  2OOT A;  3SJG A;  4MI1 A;  3TLE A;  1EZA A;  4P4F A;  4C8C A;  3BHX A;  2YU9 A;  4J0N A;  3SJX A;  2LPI A;  4MCS A;  2LTH A;  3IWW A;  4COB A;  1TWH A;  4V2R A;  1NBW A;  1ZL0 A;  2YII A;  2DIK A;  1SMY D;  3LRD A;  2C6G A;  2X0P A;  2HWG A;  1J3L A;  3BI1 A;  3U4Q A;  3K4I A;  2Y0N A;  1TWA A;  3FKI A;  4IIX A;  1I6V D;  4QIW A;  3CQZ A;  4P4J A;  4W9Y A;  4YN3 A;  2A69 D;  4CQ5 A;  1VI4 A;  3TLG A;  4C8A A;  1DE4 C;  2EK8 A;  4NGQ A;  2A6E D;  2OR4 A;  3KAS A;  3U1B A;  2EZA A;  3GJZ A;  1Y2M A;  5JVL A;  4C5R A;  3VTA A;  1R9T A;  2VK9 A;  5F1Y A;  2FIO A;  4NGM A;  5IB9 A;  4COG A;  4C8P A;  2HI6 A;  2XEG A;  3GTP A;  2JA5 A;  3NOJ A;  3SR3 A;  3BXM A;  4FBS A;  3FED A;  2JA7 A;  3H0G A;  5F5X A;  1GGO A;  3TLB A;  2R7Z A;  4CO9 A;  1T36 B;  1ZYM A;  1K83 A;  4P44 A;  1ZYR D;  4JVO A;  4CEH A;  2R92 A;  1JDB C;  4P4E A;  3RBU A;  2X0O A;  4EYS A;  1JDE A;  4OME A;  4V2Q A;  2LKM B;  4MCP A;  2MQA A;  4OC3 A;  2B63 A;  1T6J A;  2C6C A;  1CX8 A;  3T07 A;  2N3E A;  4C8F A;  4IIY A;  1T6P A;  1SFO A;  4JZ0 A;  2NVX A;  1C3O B;  1TWF A;  3S9N A;  3LR2 A;  2AUN A;  3FEC A;  3EZE A;  4C6G A;  1Z8L A;  3TLC A;  1CS0 B;  2MP0 A;  1CE8 B;  1KEE B;  2FIP A;  4P4D A;  4H1H A;  3TLY A;  2VUM A;  1BXR B;  4C9V A;  2EK9 A;  3EZA A;  4CZ1 A;  2X0Q A;  2C5Q A;  3I74 A;  1TWG A;  5IR2 A;  5F09 A;  2EZC A;  2R82 A;  3TLA A;  4E5S A;  2YJT A;  1W27 A;  2LYI A;  1I50 A;  3GTQ A;  4C5U A;  3GTJ A;  1WCM A;  4X3R A;  5IZ2 A;  4C5S A;  2JBK A;  2K3N A;  4C84 A;  2K3O A;  2AQL A;  1I3Q A;  2D0P A;  4C8U A;  5JYB A;  4CDK A;  4P45 A;  4NGN A;  1R61 A;  2LPJ A;  4C9A A;  1Y1V A;  2XEI A;  4E94 A;  1C30 B;  3LR8 A; 
#chains in the Genus database with same CATH homology
 1EZB A;  2HWG A;  2OLS A;  2X0S A;  3T05 A;  3EZE A;  2EZB A;  2EZA A;  3EZB A;  5JVL A;  1KBL A;  1VBG A;  2E28 A;  3EZA A;  2EZC A;  2R82 A;  2HRO A;  1VBH A;  3T07 A;  1DIK A;  2HI6 A;  1GGO A;  1EZA A;  1ZYM A;  2FM4 A;  3T0T A;  1JDE A;  1KC7 A;  2DIK A;  2MP0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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