1EZAA

Amino terminal domain of enzyme i from escherichia coli nmr, restrained regularized mean structure
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
259
structure length
259
Chain Sequence
MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRAVQEQVASEKAELAKLKDR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords ENZYME I
publication title Solution structure of the 30 kDa N-terminal domain of enzyme I of the Escherichia coli phosphoenolpyruvate:sugar phosphotransferase system by multidimensional NMR.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Phosphotransferase
total genus 73
structure length 259
sequence length 259
ec nomenclature ec 2.7.3.9: Phosphoenolpyruvate--protein phosphotransferase.
pdb deposition date 1997-01-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00391 PEP-utilizers PEP-utilising enzyme, mobile domain
A PF05524 PEP-utilisers_N PEP-utilising enzyme, N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.10 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 PtsI, HPr-binding domain 1ezaA02
3.50.30.10 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Phosphohistidine domain 1ezaA01
3EZEA 2DIKA 2FM4A 1JDEA 3EZBA 2HI6A 1EZAA 2EZCA 3T0TA 2EZBA 1KC7A 1EZBA 1KBLA 5JVLA 3T05A 1DIKA 2MP0A 3T07A 1ZYMA 2EZAA 3EZAA 2HWGA 1VBGA 2R82A 2HROA 1VBHA 2OLSA 2X0SA 2E28A 1GGOA
chains in the Genus database with same CATH superfamily
2CIJA 3IIBA 2EK8A 2O5JD 4MI1A 1KBLA 4NGQA 1DIKA 2JBJA 3GTOA 4TWEA 4EYSA 1T6PA 2EK9A 1TWFA 4COGA 4YN3A 1T6JA 4OC1A 3D7FA 2F5JA 1NBWA 4JZ0A 3H0GA 4C5SA 2JA6A 2D0OA 3S9LA 2YIIA 1R9TA 3SJFA 1SFOA 2X0PA 2MX9A 1JDBC 3VTAA 3SJEA 4C5UA 3FECA 2R7ZA 4NGNA 4MCSA 2FM4A 1K83A 2K3NA 1C3OB 3EZBA 5JVLA 3TLZA 2HROA 4OC2A 1DE4C 2VK9A 3IWWA 1CE8B 3SJXA 1TWCA 4P4EA 3GTJA 4NGRA 2EZCA 3T0TA 4C99A 1A9XB 3KRVA 4P4FA 3EZEA 2CW0D 2NVXA 2B63A 4BABA 1ZL0A 1IW7D 5IB9A 2NVYA 3EZAA 3FEDA 5F9MA 4TJVA 2A6ED 3C8OA 2AQLA 3U44A 4E5SA 3GTMA 2OOTA 2PVWA 2FIOA 4P4DA 1WVMA 2A69D 4V2QA 3T07A 3S9NA 3GTGA 2XEJA 4C8FA 3CQZA 3I6SA 4OC0A 4P45A 4M8DA 4C8CA 5ELYA 4QIWA 1T36B 2C6GA 4CZ1A 1Y9ZA 2EZBA 4JVOA 3GTQA 4C85A 5F09A 2D0PA 2R82A 4C9RA 4C8UA 3BI0A 4C9UA 2C5QA 1Y1WA 3T5MA 1YNND 1C30B 3TLGB 4CEJA 4X3RA 2Y0NA 3RBUA 2C6PA 1CX8A 4C9VA 2YJVA 2AUMA 4C5RA 2VUMA 2X0QA 2LPJA 5F5XA 2B0AA 2PVVA 2LYIA 1TWAA 3SR3A 3LR8A 2OR4A 2X0SA 2E28A 2FIPA 4V2RA 4LQGA 2MQAA 2N1DB 4P44A 1BXRB 4IIXA 2A68D 2A6HD 1VI4A 3K4IA 1R61A 1ZYRD 4OC5A 4MCQA 2DIKA 4W9YA 5JYBA 2R93A 3TLCA 3S9MA 4COBA 4C8PA 4OC3A 4NGSA 3GTKA 2HWGA 2X0OA 4NGPA 3LRDA 3U4QA 4NGTA 4CEIA 1I6VD 1M6VB 3G23A 4C9EA 5FD8A 2MP0A 4CQ5A 1ZYMA 4CO9A 3TLAA 3FEEA 1NXJA 4CDKA 2AUNA 3TLBA 4P4JA 1YNJD 3KASA 2K3QA 5D29A 1J3LA 2GP4A 3I74A 4P4IA 3SJGA 1ZRSA 4OC4A 2XEGA 2E2HA 1CS0B 1HQMD 3D7DA 3NOJA 2OLSA 4C2MA 3BI1A 4C9AA 4NGMA 4C6GA 4C84A 4MJXA 1EZBA 3TLYA 5IZ2A 3GJZA 1Y2MA 1Q5XA 2XEIA 4CDJA 2C6CA 3FF3A 3D7GA 4J0NA 3D7HA 4E94A 4INJA 1GGOA 1Y1VA 4H1HA 5K99A 4KNGE 4OMEA 1I50A 1KEEB 1V6CA 3ICUA 4C8AA 4TJXA 2PCNA 1JDEA 1TWGA 2HI6A 3FKIA 3GTLA 3NZ4A 2JA5A 4P4BA 4MCRA 1TWHA 2LTHA 1EZAA 3TLEA 2YJTA 4FBSA 3T05A 3BXMA 2JA7A 2MX8A 2R92A 3K9TA 1XF1A 4CEHA 5IR2A 2XEFA 1I3QA 4C8TA 3U1BA 1W27A 4BAAA 2JBKA 5F1YA 3LR6A 1SMYD 3TLGA 4IIYA 4JYWA 4MCPA 3BHXA 1Z8LA 3EIFA 1KC7A 2LKMB 2EZAA 1VBGA 2E2IA 2BE5D 2K3OA 1WCMA 2N3EA 1VBHA 2LPIA 3LR2A 2YU9A 3GTPA 3TYXA 4C86A
chains in the Genus database with same CATH topology
3EZEA 2DIKA 2FM4A 1JDEA 3EZBA 2HI6A 1EZAA 2EZCA 3T0TA 2EZBA 1KC7A 1EZBA 1KBLA 5JVLA 3T05A 1DIKA 2MP0A 3T07A 1ZYMA 2EZAA 3EZAA 2HWGA 1VBGA 2R82A 2HROA 1VBHA 2OLSA 2X0SA 2E28A 1GGOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EZE A;  2DIK A;  2FM4 A;  1JDE A;  3EZB A;  2HI6 A;  1EZA A;  2EZC A;  3T0T A;  2EZB A;  1KC7 A;  1EZB A;  1KBL A;  5JVL A;  3T05 A;  1DIK A;  2MP0 A;  3T07 A;  1ZYM A;  2EZA A;  3EZA A;  2HWG A;  1VBG A;  2R82 A;  2HRO A;  1VBH A;  2OLS A;  2X0S A;  2E28 A;  1GGO A; 
#chains in the Genus database with same CATH topology
 2CIJ A;  3IIB A;  2EK8 A;  2O5J D;  4MI1 A;  1KBL A;  4NGQ A;  1DIK A;  2JBJ A;  3GTO A;  4TWE A;  4EYS A;  1T6P A;  2EK9 A;  1TWF A;  4COG A;  4YN3 A;  1T6J A;  4OC1 A;  3D7F A;  2F5J A;  1NBW A;  4JZ0 A;  3H0G A;  4C5S A;  2JA6 A;  2D0O A;  3S9L A;  2YII A;  1R9T A;  3SJF A;  1SFO A;  2X0P A;  2MX9 A;  1JDB C;  3VTA A;  3SJE A;  4C5U A;  3FEC A;  2R7Z A;  4NGN A;  4MCS A;  2FM4 A;  1K83 A;  2K3N A;  1C3O B;  3EZB A;  5JVL A;  3TLZ A;  2HRO A;  4OC2 A;  1DE4 C;  2VK9 A;  3IWW A;  1CE8 B;  3SJX A;  1TWC A;  4P4E A;  3GTJ A;  4NGR A;  2EZC A;  3T0T A;  4C99 A;  1A9X B;  3KRV A;  4P4F A;  3EZE A;  2CW0 D;  2NVX A;  2B63 A;  4BAB A;  1ZL0 A;  1IW7 D;  5IB9 A;  2NVY A;  3EZA A;  3FED A;  5F9M A;  4TJV A;  2A6E D;  3C8O A;  2AQL A;  3U44 A;  4E5S A;  3GTM A;  2OOT A;  2PVW A;  2FIO A;  4P4D A;  1WVM A;  2A69 D;  4V2Q A;  3T07 A;  3S9N A;  3GTG A;  2XEJ A;  4C8F A;  3CQZ A;  3I6S A;  4OC0 A;  4P45 A;  4M8D A;  4C8C A;  5ELY A;  4QIW A;  1T36 B;  2C6G A;  4CZ1 A;  1Y9Z A;  2EZB A;  4JVO A;  3GTQ A;  4C85 A;  5F09 A;  2D0P A;  2R82 A;  4C9R A;  4C8U A;  3BI0 A;  4C9U A;  2C5Q A;  1Y1W A;  3T5M A;  1YNN D;  1C30 B;  3TLG B;  4CEJ A;  4X3R A;  2Y0N A;  3RBU A;  2C6P A;  1CX8 A;  4C9V A;  2YJV A;  2AUM A;  4C5R A;  2VUM A;  2X0Q A;  2LPJ A;  5F5X A;  2B0A A;  2PVV A;  2LYI A;  1TWA A;  3SR3 A;  3LR8 A;  2OR4 A;  2X0S A;  2E28 A;  2FIP A;  4V2R A;  4LQG A;  2MQA A;  2N1D B;  4P44 A;  1BXR B;  4IIX A;  2A68 D;  2A6H D;  1VI4 A;  3K4I A;  1R61 A;  1ZYR D;  4OC5 A;  4MCQ A;  2DIK A;  4W9Y A;  5JYB A;  2R93 A;  3TLC A;  3S9M A;  4COB A;  4C8P A;  4OC3 A;  4NGS A;  3GTK A;  2HWG A;  2X0O A;  4NGP A;  3LRD A;  3U4Q A;  4NGT A;  4CEI A;  1I6V D;  1M6V B;  3G23 A;  4C9E A;  5FD8 A;  2MP0 A;  4CQ5 A;  1ZYM A;  4CO9 A;  3TLA A;  3FEE A;  1NXJ A;  4CDK A;  2AUN A;  3TLB A;  4P4J A;  1YNJ D;  3KAS A;  2K3Q A;  5D29 A;  1J3L A;  2GP4 A;  3I74 A;  4P4I A;  3SJG A;  1ZRS A;  4OC4 A;  2XEG A;  2E2H A;  1CS0 B;  1HQM D;  3D7D A;  3NOJ A;  2OLS A;  4C2M A;  3BI1 A;  4C9A A;  4NGM A;  4C6G A;  4C84 A;  4MJX A;  1EZB A;  3TLY A;  5IZ2 A;  3GJZ A;  1Y2M A;  1Q5X A;  2XEI A;  4CDJ A;  2C6C A;  3FF3 A;  3D7G A;  4J0N A;  3D7H A;  4E94 A;  4INJ A;  1GGO A;  1Y1V A;  4H1H A;  5K99 A;  4KNG E;  4OME A;  1I50 A;  1KEE B;  1V6C A;  3ICU A;  4C8A A;  4TJX A;  2PCN A;  1JDE A;  1TWG A;  2HI6 A;  3FKI A;  3GTL A;  3NZ4 A;  2JA5 A;  4P4B A;  4MCR A;  1TWH A;  2LTH A;  1EZA A;  3TLE A;  2YJT A;  4FBS A;  3T05 A;  3BXM A;  2JA7 A;  2MX8 A;  2R92 A;  3K9T A;  1XF1 A;  4CEH A;  5IR2 A;  2XEF A;  1I3Q A;  4C8T A;  3U1B A;  1W27 A;  4BAA A;  2JBK A;  5F1Y A;  3LR6 A;  1SMY D;  3TLG A;  4IIY A;  4JYW A;  4MCP A;  3BHX A;  1Z8L A;  3EIF A;  1KC7 A;  2LKM B;  2EZA A;  1VBG A;  2E2I A;  2BE5 D;  2K3O A;  1WCM A;  2N3E A;  1VBH A;  2LPI A;  3LR2 A;  2YU9 A;  3GTP A;  3TYX A;  4C86 A; 
#chains in the Genus database with same CATH homology
 3EZE A;  2DIK A;  2FM4 A;  1JDE A;  3EZB A;  2HI6 A;  1EZA A;  2EZC A;  3T0T A;  2EZB A;  1KC7 A;  1EZB A;  1KBL A;  5JVL A;  3T05 A;  1DIK A;  2MP0 A;  3T07 A;  1ZYM A;  2EZA A;  3EZA A;  2HWG A;  1VBG A;  2R82 A;  2HRO A;  1VBH A;  2OLS A;  2X0S A;  2E28 A;  1GGO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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