3EZEA

Complex of the amino terminal domain of enzyme i and the histidine-containing phosphocarrier protein hpr from escherichia coli nmr, restrained regularized mean structure
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
249
structure length
249
Chain Sequence
MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRAVQEQVASE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the 40,000 Mr phosphoryl transfer complex between the N-terminal domain of enzyme I and HPr.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Transferase
molecule keywords PROTEIN (PHOSPHOTRANSFERASE SYSTEM, ENZYME I)
total genus 75
structure length 249
sequence length 249
ec nomenclature ec 2.7.3.9: Phosphoenolpyruvate--protein phosphotransferase.
pdb deposition date 1998-11-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00391 PEP-utilizers PEP-utilising enzyme, mobile domain
A PF05524 PEP-utilisers_N PEP-utilising enzyme, N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.10 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 PtsI, HPr-binding domain 3ezeA02
3.50.30.10 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Phosphohistidine domain 3ezeA01
3EZBA 2EZBA 1JDEA 1VBHA 2FM4A 2HROA 3T05A 2HI6A 2EZAA 1VBGA 2X0SA 2HWGA 2EZCA 1KC7A 2DIKA 3EZEA 1EZBA 2E28A 2R82A 2MP0A 1DIKA 3T07A 1EZAA 1GGOA 5JVLA 2OLSA 1KBLA 3EZAA 1ZYMA 3T0TA
chains in the Genus database with same CATH superfamily
1T6JA 4C8FA 1KEEB 3EZBA 1HQMD 4P4DA 5K99A 5JYBA 2MX9A 3D7GA 1SFOA 2K3QA 4P4IA 2R93A 1JDEA 3G23A 4IIYA 2E2IA 2HI6A 4C9EA 4C8TA 2EZAA 4V2QA 4C9UA 2EZCA 3TLGA 2D0PA 1XF1A 4CDJA 2XEIA 3TLCA 1I3QA 4C5UA 1ZL0A 2LYIA 2E28A 3C8OA 4COBA 1K83A 1ZYRD 1W27A 2YIIA 5F9MA 3T5MA 4W9YA 3GTPA 1EZAA 2AUMA 4MCPA 5JVLA 3NZ4A 4OC4A 2AUNA 1KBLA 1C30B 3EZAA 2C6GA 4NGMA 3LR6A 2LTHA 3BI0A 3U44A 2F5JA 4C2MA 1TWFA 2C6PA 4P45A 2N1DB 5F09A 2JBKA 3D7FA 4LQGA 4C9RA 2XEFA 3S9MA 1Y2MA 4CEIA 2B63A 3BI1A 3TLBA 1DE4C 1VI4A 3I6SA 1CE8B 4TJXA 3K9TA 2FM4A 2HROA 3I74A 1R9TA 2NVYA 2YJVA 3K4IA 4P4FA 2X0SA 1BXRB 5ELYA 1Y9ZA 4CQ5A 3S9NA 2FIPA 2C5QA 5F5XA 2DIKA 3ICUA 1EZBA 2JA6A 4MI1A 2X0OA 3FEEA 3TLAA 2XEGA 4NGSA 2MP0A 4TWEA 3SR3A 4C8UA 4E5SA 2PVVA 2A68D 1J3LA 3BHXA 3LR8A 4C5SA 3U4QA 4CEJA 1T36B 4MJXA 4OC0A 2D0OA 4OC1A 3U1BA 2OLSA 5D29A 1WCMA 4NGTA 4COGA 4NGQA 2BE5D 3KASA 2FIOA 4C85A 2NVXA 4BABA 2MX8A 2N3EA 2OOTA 1KC7A 1NBWA 3TLZA 4OC5A 3T0TA 5IR2A 2PVWA 1Y1WA 2B0AA 4INJA 4C8CA 4C99A 2GP4A 2MQAA 1Q5XA 4OC3A 1IW7D 3TLEA 3FECA 4KNGE 4EYSA 4YN3A 1SMYD 2CW0D 4MCSA 3H0GA 2EK9A 1VBHA 3T05A 1YNJD 1NXJA 4P4BA 3LR2A 4CO9A 2K3NA 3TLYA 1VBGA 2HWGA 2YJTA 3FF3A 2XEJA 5F1YA 5IB9A 3S9LA 5IZ2A 3EZEA 3GTGA 2R7ZA 3RBUA 1T6PA 2YU9A 3FEDA 4IIXA 1TWHA 1I50A 4P44A 1M6VB 1DIKA 1WVMA 4M8DA 3CQZA 4MCRA 5FD8A 1GGOA 1Z8LA 4JYWA 1CX8A 4OC2A 3D7DA 4FBSA 1C3OB 1ZRSA 4BAAA 2R92A 2O5JD 3IWWA 4CDKA 4JVOA 3D7HA 3GTMA 4X3RA 3SJGA 3NOJA 2VK9A 2AQLA 1YNND 3GTJA 2CIJA 4V2RA 4NGNA 3GTKA 4H1HA 4NGRA 4P4EA 1R61A 4C8PA 4C8AA 3VTAA 2EZBA 3SJEA 3BXMA 2A6ED 2JBJA 2K3OA 2LKMB 3LRDA 3GTLA 3SJXA 4C84A 4C9VA 2JA7A 2LPIA 2LPJA 1CS0B 2A6HD 1Y1VA 2X0PA 4TJVA 3GTOA 4JZ0A 3TLGB 1A9XB 4C9AA 1I6VD 4C5RA 3SJFA 1JDBC 1V6CA 4CEHA 2R82A 2C6CA 3EIFA 4P4JA 4OMEA 3IIBA 2VUMA 4E94A 2Y0NA 2JA5A 1TWCA 1TWAA 2OR4A 3T07A 2PCNA 2A69D 3KRVA 4C6GA 4J0NA 3GTQA 3TYXA 1TWGA 4C86A 3GJZA 3FKIA 4QIWA 4MCQA 4CZ1A 4NGPA 2EK8A 1ZYMA 2X0QA 2E2HA
chains in the Genus database with same CATH topology
3EZBA 2EZBA 1JDEA 1VBHA 2FM4A 2HROA 3T05A 2HI6A 2EZAA 1VBGA 2X0SA 2HWGA 2EZCA 1KC7A 2DIKA 3EZEA 1EZBA 2E28A 2R82A 2MP0A 1DIKA 3T07A 1EZAA 1GGOA 5JVLA 2OLSA 1KBLA 3EZAA 1ZYMA 3T0TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EZB A;  2EZB A;  1JDE A;  1VBH A;  2FM4 A;  2HRO A;  3T05 A;  2HI6 A;  2EZA A;  1VBG A;  2X0S A;  2HWG A;  2EZC A;  1KC7 A;  2DIK A;  3EZE A;  1EZB A;  2E28 A;  2R82 A;  2MP0 A;  1DIK A;  3T07 A;  1EZA A;  1GGO A;  5JVL A;  2OLS A;  1KBL A;  3EZA A;  1ZYM A;  3T0T A; 
#chains in the Genus database with same CATH topology
 1T6J A;  4C8F A;  1KEE B;  3EZB A;  1HQM D;  4P4D A;  5K99 A;  5JYB A;  2MX9 A;  3D7G A;  1SFO A;  2K3Q A;  4P4I A;  2R93 A;  1JDE A;  3G23 A;  4IIY A;  2E2I A;  2HI6 A;  4C9E A;  4C8T A;  2EZA A;  4V2Q A;  4C9U A;  2EZC A;  3TLG A;  2D0P A;  1XF1 A;  4CDJ A;  2XEI A;  3TLC A;  1I3Q A;  4C5U A;  1ZL0 A;  2LYI A;  2E28 A;  3C8O A;  4COB A;  1K83 A;  1ZYR D;  1W27 A;  2YII A;  5F9M A;  3T5M A;  4W9Y A;  3GTP A;  1EZA A;  2AUM A;  4MCP A;  5JVL A;  3NZ4 A;  4OC4 A;  2AUN A;  1KBL A;  1C30 B;  3EZA A;  2C6G A;  4NGM A;  3LR6 A;  2LTH A;  3BI0 A;  3U44 A;  2F5J A;  4C2M A;  1TWF A;  2C6P A;  4P45 A;  2N1D B;  5F09 A;  2JBK A;  3D7F A;  4LQG A;  4C9R A;  2XEF A;  3S9M A;  1Y2M A;  4CEI A;  2B63 A;  3BI1 A;  3TLB A;  1DE4 C;  1VI4 A;  3I6S A;  1CE8 B;  4TJX A;  3K9T A;  2FM4 A;  2HRO A;  3I74 A;  1R9T A;  2NVY A;  2YJV A;  3K4I A;  4P4F A;  2X0S A;  1BXR B;  5ELY A;  1Y9Z A;  4CQ5 A;  3S9N A;  2FIP A;  2C5Q A;  5F5X A;  2DIK A;  3ICU A;  1EZB A;  2JA6 A;  4MI1 A;  2X0O A;  3FEE A;  3TLA A;  2XEG A;  4NGS A;  2MP0 A;  4TWE A;  3SR3 A;  4C8U A;  4E5S A;  2PVV A;  2A68 D;  1J3L A;  3BHX A;  3LR8 A;  4C5S A;  3U4Q A;  4CEJ A;  1T36 B;  4MJX A;  4OC0 A;  2D0O A;  4OC1 A;  3U1B A;  2OLS A;  5D29 A;  1WCM A;  4NGT A;  4COG A;  4NGQ A;  2BE5 D;  3KAS A;  2FIO A;  4C85 A;  2NVX A;  4BAB A;  2MX8 A;  2N3E A;  2OOT A;  1KC7 A;  1NBW A;  3TLZ A;  4OC5 A;  3T0T A;  5IR2 A;  2PVW A;  1Y1W A;  2B0A A;  4INJ A;  4C8C A;  4C99 A;  2GP4 A;  2MQA A;  1Q5X A;  4OC3 A;  1IW7 D;  3TLE A;  3FEC A;  4KNG E;  4EYS A;  4YN3 A;  1SMY D;  2CW0 D;  4MCS A;  3H0G A;  2EK9 A;  1VBH A;  3T05 A;  1YNJ D;  1NXJ A;  4P4B A;  3LR2 A;  4CO9 A;  2K3N A;  3TLY A;  1VBG A;  2HWG A;  2YJT A;  3FF3 A;  2XEJ A;  5F1Y A;  5IB9 A;  3S9L A;  5IZ2 A;  3EZE A;  3GTG A;  2R7Z A;  3RBU A;  1T6P A;  2YU9 A;  3FED A;  4IIX A;  1TWH A;  1I50 A;  4P44 A;  1M6V B;  1DIK A;  1WVM A;  4M8D A;  3CQZ A;  4MCR A;  5FD8 A;  1GGO A;  1Z8L A;  4JYW A;  1CX8 A;  4OC2 A;  3D7D A;  4FBS A;  1C3O B;  1ZRS A;  4BAA A;  2R92 A;  2O5J D;  3IWW A;  4CDK A;  4JVO A;  3D7H A;  3GTM A;  4X3R A;  3SJG A;  3NOJ A;  2VK9 A;  2AQL A;  1YNN D;  3GTJ A;  2CIJ A;  4V2R A;  4NGN A;  3GTK A;  4H1H A;  4NGR A;  4P4E A;  1R61 A;  4C8P A;  4C8A A;  3VTA A;  2EZB A;  3SJE A;  3BXM A;  2A6E D;  2JBJ A;  2K3O A;  2LKM B;  3LRD A;  3GTL A;  3SJX A;  4C84 A;  4C9V A;  2JA7 A;  2LPI A;  2LPJ A;  1CS0 B;  2A6H D;  1Y1V A;  2X0P A;  4TJV A;  3GTO A;  4JZ0 A;  3TLG B;  1A9X B;  4C9A A;  1I6V D;  4C5R A;  3SJF A;  1JDB C;  1V6C A;  4CEH A;  2R82 A;  2C6C A;  3EIF A;  4P4J A;  4OME A;  3IIB A;  2VUM A;  4E94 A;  2Y0N A;  2JA5 A;  1TWC A;  1TWA A;  2OR4 A;  3T07 A;  2PCN A;  2A69 D;  3KRV A;  4C6G A;  4J0N A;  3GTQ A;  3TYX A;  1TWG A;  4C86 A;  3GJZ A;  3FKI A;  4QIW A;  4MCQ A;  4CZ1 A;  4NGP A;  2EK8 A;  1ZYM A;  2X0Q A;  2E2H A; 
#chains in the Genus database with same CATH homology
 3EZB A;  2EZB A;  1JDE A;  1VBH A;  2FM4 A;  2HRO A;  3T05 A;  2HI6 A;  2EZA A;  1VBG A;  2X0S A;  2HWG A;  2EZC A;  1KC7 A;  2DIK A;  3EZE A;  1EZB A;  2E28 A;  2R82 A;  2MP0 A;  1DIK A;  3T07 A;  1EZA A;  1GGO A;  5JVL A;  2OLS A;  1KBL A;  3EZA A;  1ZYM A;  3T0T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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