3EZEA

Complex of the amino terminal domain of enzyme i and the histidine-containing phosphocarrier protein hpr from escherichia coli nmr, restrained regularized mean structure
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
249
structure length
249
Chain Sequence
MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRAVQEQVASE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords PROTEIN (PHOSPHOTRANSFERASE SYSTEM, ENZYME I)
publication title Solution structure of the 40,000 Mr phosphoryl transfer complex between the N-terminal domain of enzyme I and HPr.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Transferase
total genus 75
structure length 249
sequence length 249
ec nomenclature ec 2.7.3.9: Phosphoenolpyruvate--protein phosphotransferase.
pdb deposition date 1998-11-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00391 PEP-utilizers PEP-utilising enzyme, mobile domain
A PF05524 PEP-utilisers_N PEP-utilising enzyme, N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.10 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 PtsI, HPr-binding domain 3ezeA02
3.50.30.10 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Phosphohistidine domain 3ezeA01
2DIKA 2HROA 5JVLA 2E28A 1GGOA 2HI6A 1EZAA 3EZBA 2R82A 3EZEA 1DIKA 1ZYMA 1EZBA 1KC7A 3T0TA 2EZCA 2FM4A 3T05A 2HWGA 1VBGA 2MP0A 1KBLA 3EZAA 2EZBA 2X0SA 2OLSA 1JDEA 2EZAA 3T07A 1VBHA
chains in the Genus database with same CATH superfamily
2DIKA 3VTAA 2E28A 4NGTA 4P45A 4BAAA 2X0QA 3D7FA 4P4DA 2LKMB 4OC5A 3I6SA 5FD8A 2K3QA 1Y1WA 2EZAA 3EZBA 4W9YA 2JBKA 3SJXA 2Y0NA 4C6GA 4EYSA 1Y2MA 3GTGA 3GTOA 3IIBA 2CW0D 1T6PA 5F09A 1ZL0A 2CIJA 5F1YA 1M6VB 2OR4A 3IWWA 2FIOA 2R7ZA 4OC2A 2C5QA 2MP0A 2R92A 4COBA 1V6CA 4C8AA 1HQMD 5IB9A 1NXJA 3NOJA 4TJXA 4JYWA 3NZ4A 4CEIA 4OC4A 4C86A 3TLGA 1KC7A 3T0TA 3TLZA 4OC1A 2EK8A 4NGPA 1TWHA 1W27A 4MJXA 2EZBA 3FEEA 1T36B 4C9VA 1JDEA 1J3LA 2JBJA 2A68D 1GGOA 5D29A 3D7DA 2AUNA 1C3OB 3TYXA 1ZYMA 1EZBA 4YN3A 2D0PA 2MX9A 3SJEA 2EK9A 3S9MA 4P44A 4QIWA 2F5JA 3K4IA 4P4JA 4COGA 3GTPA 3T07A 2PCNA 3LR6A 2AUMA 2R93A 4NGNA 4C5UA 4J0NA 2X0PA 2C6CA 4KNGE 2JA6A 1A9XB 4H1HA 2FIPA 2OLSA 1VI4A 3U1BA 2HROA 3FEDA 1CE8B 2HI6A 4JZ0A 1DIKA 1SMYD 2YJVA 1XF1A 4OC0A 1BXRB 5K99A 4JVOA 2B0AA 1I50A 3SJFA 1EZAA 3TLCA 3EZEA 1Y9ZA 4P4BA 4P4EA 3BI0A 3TLEA 1JDBC 4MCSA 4MCRA 2XEIA 3S9LA 1WCMA 2X0SA 2JA7A 4V2QA 4NGRA 4C99A 3TLYA 4C8CA 1SFOA 3KASA 4IIYA 1TWFA 1KEEB 3CQZA 5IR2A 3FKIA 4OMEA 5F9MA 2N3EA 1Q5XA 2E2IA 2VUMA 2NVXA 3G23A 2NVYA 1ZRSA 1R61A 2D0OA 2E2HA 4CEJA 4C85A 4TJVA 4C9UA 2VK9A 4C9AA 2A6ED 2A69D 2K3NA 3T5MA 2EZCA 3TLBA 2LPJA 4NGQA 1VBGA 5F5XA 2O5JD 2GP4A 1TWCA 1ZYRD 3EIFA 3D7GA 2LPIA 1VBHA 4C9RA 5JVLA 1TWAA 3GTQA 2R82A 5JYBA 3H0GA 3GTJA 4OC3A 2YJTA 2X0OA 2YIIA 4MCQA 2MX8A 3K9TA 4C9EA 1CS0B 2MQAA 2AQLA 4CO9A 2PVVA 3KRVA 3TLAA 4C5SA 1NBWA 2XEFA 4C5RA 1C30B 3U44A 1IW7D 2LYIA 4V2RA 4NGSA 3BXMA 3SR3A 4P4FA 2LTHA 3U4QA 3S9NA 3TLGB 2B63A 1R9TA 4C8PA 3GTMA 2C6PA 4INJA 2YU9A 4C2MA 3FECA 4TWEA 4X3RA 3C8OA 4E94A 2HWGA 4CQ5A 1KBLA 4NGMA 3EZAA 3GJZA 4MCPA 2C6GA 3BHXA 3BI1A 3FF3A 4CZ1A 5ELYA 4C8FA 3GTLA 2XEJA 4E5SA 1DE4C 4MI1A 1Y1VA 3LRDA 1YNJD 2A6HD 4IIXA 1CX8A 4CEHA 3LR2A 4C84A 4C8UA 4LQGA 4P4IA 3I74A 1T6JA 1WVMA 2XEGA 3T05A 3SJGA 1I6VD 1TWGA 3GTKA 2BE5D 2PVWA 3LR8A 1Z8LA 2N1DB 4C8TA 3D7HA 1K83A 4M8DA 1YNND 3ICUA 2JA5A 4CDJA 5IZ2A 1I3QA 4BABA 3RBUA 4CDKA 2FM4A 4FBSA 2K3OA 2OOTA
chains in the Genus database with same CATH topology
2DIKA 2HROA 5JVLA 2E28A 1GGOA 2HI6A 1EZAA 3EZBA 2R82A 3EZEA 1DIKA 1ZYMA 1EZBA 1KC7A 3T0TA 2EZCA 2FM4A 3T05A 2HWGA 1VBGA 2MP0A 1KBLA 3EZAA 2EZBA 2X0SA 2OLSA 1JDEA 2EZAA 3T07A 1VBHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DIK A;  2HRO A;  5JVL A;  2E28 A;  1GGO A;  2HI6 A;  1EZA A;  3EZB A;  2R82 A;  3EZE A;  1DIK A;  1ZYM A;  1EZB A;  1KC7 A;  3T0T A;  2EZC A;  2FM4 A;  3T05 A;  2HWG A;  1VBG A;  2MP0 A;  1KBL A;  3EZA A;  2EZB A;  2X0S A;  2OLS A;  1JDE A;  2EZA A;  3T07 A;  1VBH A; 
#chains in the Genus database with same CATH topology
 2DIK A;  3VTA A;  2E28 A;  4NGT A;  4P45 A;  4BAA A;  2X0Q A;  3D7F A;  4P4D A;  2LKM B;  4OC5 A;  3I6S A;  5FD8 A;  2K3Q A;  1Y1W A;  2EZA A;  3EZB A;  4W9Y A;  2JBK A;  3SJX A;  2Y0N A;  4C6G A;  4EYS A;  1Y2M A;  3GTG A;  3GTO A;  3IIB A;  2CW0 D;  1T6P A;  5F09 A;  1ZL0 A;  2CIJ A;  5F1Y A;  1M6V B;  2OR4 A;  3IWW A;  2FIO A;  2R7Z A;  4OC2 A;  2C5Q A;  2MP0 A;  2R92 A;  4COB A;  1V6C A;  4C8A A;  1HQM D;  5IB9 A;  1NXJ A;  3NOJ A;  4TJX A;  4JYW A;  3NZ4 A;  4CEI A;  4OC4 A;  4C86 A;  3TLG A;  1KC7 A;  3T0T A;  3TLZ A;  4OC1 A;  2EK8 A;  4NGP A;  1TWH A;  1W27 A;  4MJX A;  2EZB A;  3FEE A;  1T36 B;  4C9V A;  1JDE A;  1J3L A;  2JBJ A;  2A68 D;  1GGO A;  5D29 A;  3D7D A;  2AUN A;  1C3O B;  3TYX A;  1ZYM A;  1EZB A;  4YN3 A;  2D0P A;  2MX9 A;  3SJE A;  2EK9 A;  3S9M A;  4P44 A;  4QIW A;  2F5J A;  3K4I A;  4P4J A;  4COG A;  3GTP A;  3T07 A;  2PCN A;  3LR6 A;  2AUM A;  2R93 A;  4NGN A;  4C5U A;  4J0N A;  2X0P A;  2C6C A;  4KNG E;  2JA6 A;  1A9X B;  4H1H A;  2FIP A;  2OLS A;  1VI4 A;  3U1B A;  2HRO A;  3FED A;  1CE8 B;  2HI6 A;  4JZ0 A;  1DIK A;  1SMY D;  2YJV A;  1XF1 A;  4OC0 A;  1BXR B;  5K99 A;  4JVO A;  2B0A A;  1I50 A;  3SJF A;  1EZA A;  3TLC A;  3EZE A;  1Y9Z A;  4P4B A;  4P4E A;  3BI0 A;  3TLE A;  1JDB C;  4MCS A;  4MCR A;  2XEI A;  3S9L A;  1WCM A;  2X0S A;  2JA7 A;  4V2Q A;  4NGR A;  4C99 A;  3TLY A;  4C8C A;  1SFO A;  3KAS A;  4IIY A;  1TWF A;  1KEE B;  3CQZ A;  5IR2 A;  3FKI A;  4OME A;  5F9M A;  2N3E A;  1Q5X A;  2E2I A;  2VUM A;  2NVX A;  3G23 A;  2NVY A;  1ZRS A;  1R61 A;  2D0O A;  2E2H A;  4CEJ A;  4C85 A;  4TJV A;  4C9U A;  2VK9 A;  4C9A A;  2A6E D;  2A69 D;  2K3N A;  3T5M A;  2EZC A;  3TLB A;  2LPJ A;  4NGQ A;  1VBG A;  5F5X A;  2O5J D;  2GP4 A;  1TWC A;  1ZYR D;  3EIF A;  3D7G A;  2LPI A;  1VBH A;  4C9R A;  5JVL A;  1TWA A;  3GTQ A;  2R82 A;  5JYB A;  3H0G A;  3GTJ A;  4OC3 A;  2YJT A;  2X0O A;  2YII A;  4MCQ A;  2MX8 A;  3K9T A;  4C9E A;  1CS0 B;  2MQA A;  2AQL A;  4CO9 A;  2PVV A;  3KRV A;  3TLA A;  4C5S A;  1NBW A;  2XEF A;  4C5R A;  1C30 B;  3U44 A;  1IW7 D;  2LYI A;  4V2R A;  4NGS A;  3BXM A;  3SR3 A;  4P4F A;  2LTH A;  3U4Q A;  3S9N A;  3TLG B;  2B63 A;  1R9T A;  4C8P A;  3GTM A;  2C6P A;  4INJ A;  2YU9 A;  4C2M A;  3FEC A;  4TWE A;  4X3R A;  3C8O A;  4E94 A;  2HWG A;  4CQ5 A;  1KBL A;  4NGM A;  3EZA A;  3GJZ A;  4MCP A;  2C6G A;  3BHX A;  3BI1 A;  3FF3 A;  4CZ1 A;  5ELY A;  4C8F A;  3GTL A;  2XEJ A;  4E5S A;  1DE4 C;  4MI1 A;  1Y1V A;  3LRD A;  1YNJ D;  2A6H D;  4IIX A;  1CX8 A;  4CEH A;  3LR2 A;  4C84 A;  4C8U A;  4LQG A;  4P4I A;  3I74 A;  1T6J A;  1WVM A;  2XEG A;  3T05 A;  3SJG A;  1I6V D;  1TWG A;  3GTK A;  2BE5 D;  2PVW A;  3LR8 A;  1Z8L A;  2N1D B;  4C8T A;  3D7H A;  1K83 A;  4M8D A;  1YNN D;  3ICU A;  2JA5 A;  4CDJ A;  5IZ2 A;  1I3Q A;  4BAB A;  3RBU A;  4CDK A;  2FM4 A;  4FBS A;  2K3O A;  2OOT A; 
#chains in the Genus database with same CATH homology
 2DIK A;  2HRO A;  5JVL A;  2E28 A;  1GGO A;  2HI6 A;  1EZA A;  3EZB A;  2R82 A;  3EZE A;  1DIK A;  1ZYM A;  1EZB A;  1KC7 A;  3T0T A;  2EZC A;  2FM4 A;  3T05 A;  2HWG A;  1VBG A;  2MP0 A;  1KBL A;  3EZA A;  2EZB A;  2X0S A;  2OLS A;  1JDE A;  2EZA A;  3T07 A;  1VBH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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