2AQLA

Crystal structure of the mrg15 mrg domain
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
167
structure length
158
Chain Sequence
EVKVKIPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDYANYKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILADHPDAPMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLNYLHDFLKYLAKNSATLFSASDYEVAPPEYHRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Multipurpose MRG domain involved in cell senescence and proliferation exhibits structural homology to a DNA-interacting domain.
pubmed doi rcsb
molecule keywords Mortality factor 4-like protein 1
molecule tags Dna binding protein
source organism Homo sapiens
total genus 54
structure length 158
sequence length 167
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-08-18
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.30 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 Enzyme I; Chain A, domain 2 2aqlA00
2AQLA 2Y0NA 2N1DB 2F5JA 2LKMB
chains in the Genus database with same CATH superfamily
2K3QA 2O5JD 3GTKA 1I3QA 3GTQA 1YNND 4QIWA 1ZYRD 2LPJA 3GTLA 4C6GA 1HQMD 3H0GA 2Y0NA 2MX8A 3EZAA 2JA6A 2EZCA 2MP0A 1YNJD 2VUMA 2N1DB 2N3EA 3GTPA 2A69D 2X0QA 3EZEA 3LR2A 4CEJA 3LR6A 1TWGA 1Y1VA 2A6ED 1T6JA 2A6HD 1TWHA 2X0PA 2LKMB 1R9TA 2K3OA 2NVYA 2JA5A 1SFOA 3U44A 2VK9A 1Y1WA 2HWGA 2E2IA 4V2QA 4C5RA 2NVXA 1IW7D 2YIIA 2B63A 2LPIA 3U4QA 1I6VD 4C5UA 1W27A 1ZYMA 4BAAA 2K3NA 1T6PA 3GTOA 1K83A 2MQAA 1EZBA 4C2MA 2JA7A 2CW0D 2BE5D 3GTGA 1TWFA 3GTMA 2F5JA 4CEHA 1WCMA 4FBSA 4CEIA 3CQZA 2LTHA 1SMYD 1EZAA 2R7ZA 5IZ2A 3LRDA 1TWCA 1I50A 2MX9A 1TWAA 4V2RA 3FKIA 3GTJA 2A68D 2AQLA 3EZBA 2FIPA 2E2HA 1Y2MA 2HROA 2R93A 2YU9A 2EZAA 3LR8A 4CQ5A 2FIOA 3NZ4A 4BABA 2EZBA 2X0OA 2R92A 4C5SA 2LYIA
chains in the Genus database with same CATH topology
2K3QA 2O5JD 3GTKA 1I3QA 3GTQA 1YNND 4QIWA 1ZYRD 2LPJA 3GTLA 1HQMD 3H0GA 2Y0NA 2MX8A 2JA6A 1YNJD 2VUMA 2N1DB 2N3EA 3GTPA 2A69D 2X0QA 3LR2A 4CEJA 3LR6A 1TWGA 1Y1VA 2A6ED 2A6HD 1TWHA 2X0PA 2LKMB 1R9TA 2K3OA 2NVYA 2JA5A 1SFOA 3U44A 2VK9A 1Y1WA 2E2IA 2NVXA 1IW7D 2B63A 2LPIA 3U4QA 1I6VD 2K3NA 3GTOA 1K83A 2MQAA 4C2MA 2JA7A 2CW0D 2BE5D 3GTGA 1TWFA 3GTMA 2F5JA 4CEHA 1WCMA 4FBSA 4CEIA 2LTHA 3CQZA 1SMYD 2R7ZA 5IZ2A 3LRDA 1TWCA 1I50A 2MX9A 1TWAA 3FKIA 3GTJA 2A68D 2AQLA 2FIPA 2E2HA 2R93A 2YU9A 3LR8A 2FIOA 2X0OA 2R92A 2LYIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2AQL A;  2Y0N A;  2N1D B;  2F5J A;  2LKM B; 
#chains in the Genus database with same CATH topology
 2K3Q A;  2O5J D;  3GTK A;  1I3Q A;  3GTQ A;  1YNN D;  4QIW A;  1ZYR D;  2LPJ A;  3GTL A;  4C6G A;  1HQM D;  3H0G A;  2Y0N A;  2MX8 A;  3EZA A;  2JA6 A;  2EZC A;  2MP0 A;  1YNJ D;  2VUM A;  2N1D B;  2N3E A;  3GTP A;  2A69 D;  2X0Q A;  3EZE A;  3LR2 A;  4CEJ A;  3LR6 A;  1TWG A;  1Y1V A;  2A6E D;  1T6J A;  2A6H D;  1TWH A;  2X0P A;  2LKM B;  1R9T A;  2K3O A;  2NVY A;  2JA5 A;  1SFO A;  3U44 A;  2VK9 A;  1Y1W A;  2HWG A;  2E2I A;  4V2Q A;  4C5R A;  2NVX A;  1IW7 D;  2YII A;  2B63 A;  2LPI A;  3U4Q A;  1I6V D;  4C5U A;  1W27 A;  1ZYM A;  4BAA A;  2K3N A;  1T6P A;  3GTO A;  1K83 A;  2MQA A;  1EZB A;  4C2M A;  2JA7 A;  2CW0 D;  2BE5 D;  3GTG A;  1TWF A;  3GTM A;  2F5J A;  4CEH A;  1WCM A;  4FBS A;  4CEI A;  3CQZ A;  2LTH A;  1SMY D;  1EZA A;  2R7Z A;  5IZ2 A;  3LRD A;  1TWC A;  1I50 A;  2MX9 A;  1TWA A;  4V2R A;  3FKI A;  3GTJ A;  2A68 D;  2AQL A;  3EZB A;  2FIP A;  2E2H A;  1Y2M A;  2HRO A;  2R93 A;  2YU9 A;  2EZA A;  3LR8 A;  4CQ5 A;  2FIO A;  3NZ4 A;  4BAB A;  2EZB A;  2X0O A;  2R92 A;  4C5S A;  2LYI A; 
#chains in the Genus database with same CATH homology
 2K3Q A;  2O5J D;  3GTK A;  1I3Q A;  3GTQ A;  1YNN D;  4QIW A;  1ZYR D;  2LPJ A;  3GTL A;  1HQM D;  3H0G A;  2Y0N A;  2MX8 A;  2JA6 A;  1YNJ D;  2VUM A;  2N1D B;  2N3E A;  3GTP A;  2A69 D;  2X0Q A;  3LR2 A;  4CEJ A;  3LR6 A;  1TWG A;  1Y1V A;  2A6E D;  2A6H D;  1TWH A;  2X0P A;  2LKM B;  1R9T A;  2K3O A;  2NVY A;  2JA5 A;  1SFO A;  3U44 A;  2VK9 A;  1Y1W A;  2E2I A;  2NVX A;  1IW7 D;  2B63 A;  2LPI A;  3U4Q A;  1I6V D;  2K3N A;  3GTO A;  1K83 A;  2MQA A;  4C2M A;  2JA7 A;  2CW0 D;  2BE5 D;  3GTG A;  1TWF A;  3GTM A;  2F5J A;  4CEH A;  1WCM A;  4FBS A;  4CEI A;  2LTH A;  3CQZ A;  1SMY D;  2R7Z A;  5IZ2 A;  3LRD A;  1TWC A;  1I50 A;  2MX9 A;  1TWA A;  3FKI A;  3GTJ A;  2A68 D;  2AQL A;  2FIP A;  2E2H A;  2R93 A;  2YU9 A;  3LR8 A;  2FIO A;  2X0O A;  2R92 A;  2LYI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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