1T6JA

Crystal structure of phenylalanine ammonia lyase from rhodosporidium toruloides
Total Genus 233
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
233
sequence length
676
structure length
646
Chain Sequence
TTQVTQVDIVEKMLAAPTDSTLELDGYSLNLGDVVSAARKGRPVRVKDSDEIRSKIDKSVEFLRSQTEDAISLQKALLEHQLCGVLPSSFDSFRLGRGLENSLPLEVVRGAMTIRVNSLTRGHSAVRLVVLEALTNFLNHGITPIVPLRGTISDLSPLSYIAAAISGHPDSKVHVVHEGKEKILYAREAMALFNLEPVVLGPKEGLGLVNGTAVSASMATLALHDAHMLSLLSQSLTAMTVEAMVGHAGSFHPFLHDVTRPHPTQIEVAGNIRKLLEGSRFAVHHEEERQDRYPLRTSPQWLGPLVSDLIHAHAVLTIEAGQSTTDNPLIDVENKTSHHGGNFQAAAVANTMEKTRLGLAQIGKLNFTQLTEMLNAGMNRGLPSCLAAEDPSLSYHCKGLDIAAAAYTSELGHLANPVTTHVQPAEMANQAVNSLALISARRTTESNDVLSLLLATHLYCVLQAIDLRAIEFEFKKQFGPAIVSLIDQHFGSAMTGSNLRDELVEKVNKTLAKRLEQTNSYDLVPRWHDAFSFAAGTVVEVLSSTSLSLAAVNAWKVAAAESAISLTRQVRETFWSAASTSSPALSYLSPRTQILYAFVREELGVKARRGDVFLGKQEVTIGSNVSKIYEAIKSGRINNVLLKMLA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of phenylalanine ammonia lyase: multiple helix dipoles implicated in catalysis.
pubmed doi rcsb
source organism Rhodosporidium toruloides
molecule tags Lyase
molecule keywords phenylalanine ammonia-lyase
total genus 233
structure length 646
sequence length 676
chains with identical sequence B
ec nomenclature ec 4.3.1.25: Phenylalanine/tyrosine ammonia-lyase.
pdb deposition date 2004-05-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.20 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 Phenylalanine ammonia-lyase 1; domain 3 1t6jA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1t6jA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1t6jA02
4C5SA 1EB4A 3GTDA 1U16A 3KDYA 5HW2A 1TJ7A 4MX2A 1FURA 1K7WA 4BABA 2O7DA 5F91A 1HY0A 1XWOA 1HY1A 2VD6A 2OHYA 1GKJA 3R6VA 3R6QA 1VDKA 3GZHA 3UNVA 1U15A 1YFMA 3KDZA 3BHGA 3TV2A 5D6BA 4V2QA 3CZOA 1GK3A 4NLEA 2E9FA 2PTQA 1GKMA 4APBA 4NSLA 2RJRA 1T6PA 3C8TA 1GK2A 1JSWA 4BAAA 2PFMA 2YIIA 2PTSA 1FUOA 1W27A 2PTRA 2J91A 1C3CA 1J3UA 1DOFA 2QVEA 3NZ4A 4EEIA 1TJWA 3RD8A 2FUSA 1FUQA 2O6YA 2O78A 2NYNA 1K62A 5EYVA 4FLCA 5EYTA 1C3UA 4CQ5A 1YFEA 4ADMA 3OCEA 1Q5NA 2O7EA 2NYFA 4C6GA 2O7BA 4HGVA 1FUPA 2X75A 4FFXA 4ADLA 1TJVA 3RRPA 1Y2MA 4EFCA 1RE5A 3E04A 1T6JA 1KQ7A 4C5RA 3QBPA 2QGAB 5F92A 1B8FA 2RJSA 2O7FA 4C5UA 3NO9A 1DCNA 2HVGA 4V2RA 1AUWA 3OCFA 3R6YA 4APAA 1TJUA 1I0AA 1YISA
chains in the Genus database with same CATH superfamily
4C5SA 1EB4A 1TWCA 2A6HD 1U16A 2VUMA 3GTDA 3GTLA 3KDYA 5HW2A 1TJ7A 4MX2A 1FURA 1K7WA 4BABA 2K3NA 2O7DA 3GTKA 2EZAA 2NVYA 2JA6A 5F91A 2NVXA 1HY0A 1XWOA 1HY1A 2X0OA 2VD6A 3LR2A 2OHYA 1GKJA 3R6VA 2BE5D 3R6QA 1XLYA 1VDKA 1K83A 3GZHA 3UNVA 1I0AA 1IW7D 3LR6A 3LR8A 2MQAA 1SMYD 1ZYRD 1EZBA 1U15A 2HROA 1YFMA 3BHGA 3CRVA 3KDZA 3CRW1 3TV2A 5D6BA 2CW0D 2K3QA 3EZBA 4V2QA 2LPIA 3CQZA 1GK3A 3CZOA 4NLEA 2E2HA 2E9FA 1SFOA 2PTQA 1GKMA 4APBA 4NSLA 2A69D 2VK9A 2RJRA 1T6PA 1I3QA 5IZ2A 2AQLA 3C8TA 2LPJA 1GK2A 1Y1VA 1JSWA 4BAAA 2PFMA 2YIIA 3GTMA 4A15A 5H8WA 2MX9A 2PTSA 1FUOA 1W27A 3EZAA 2PTRA 4C2MA 2J91A 3GTQA 3GTJA 1C3CA 4CEJA 1J3UA 1DOFA 2A6ED 2LKMB 2HWGA 2QVEA 3NZ4A 3FKIA 1I6VD 4EEIA 1TJWA 3GTOA 3RD8A 2FUSA 1FUQA 1TWHA 2VSFA 2LTHA 1XMDA 4WNLA 2O6YA 2N3EA 1I50A 2O78A 2NYNA 2R7ZA 2FELA 2N1DB 2E2IA 1K62A 4CEHA 5EYVA 4FLCA 1YNJD 2VL7A 5EYTA 1C3UA 4CQ5A 1YFEA 2K3OA 1TWAA 4ADMA 5M0JA 2FIOA 3OCEA 1WCMA 3U4QA 2JA7A 1Q5NA 1HQMD 2O7EA 2NYFA 4C6GA 1XL8A 2O7BA 4HGVA 1FUPA 2X75A 1TWFA 4FFXA 2R92A 4ADLA 2B63A 1TJVA 3RRPA 1Y2MA 4EFCA 2X0PA 1RE5A 3E04A 1T6JA 1YNND 1KQ7A 3GTGA 2EZBA 2F5JA 2MP0A 2X0QA 4C5RA 1XL7A 3QBPA 4CEIA 2LYIA 2R93A 2QGAB 3LRDA 2JA5A 5F92A 2FENA 2EZCA 1B8FA 5M0IA 2YU9A 2RJSA 2O7FA 4C5UA 3U44A 2O5JD 1XMCA 2MX8A 1TWGA 3NO9A 4QIWA 1DCNA 3H0GA 4FBSA 3GTPA 4V2RA 1EZAA 1Y1WA 1AUWA 2HVGA 3OCFA 3R6YA 4APAA 2Y0NA 1R9TA 1TJUA 2A68D 2FIPA 1ZYMA 1YISA 3EZEA
chains in the Genus database with same CATH topology
4C5SA 1EB4A 3GTDA 1U16A 3KDYA 5HW2A 1TJ7A 4MX2A 1FURA 1K7WA 4BABA 2O7DA 5F91A 1HY0A 1XWOA 1HY1A 2VD6A 2OHYA 1GKJA 3R6VA 3R6QA 1VDKA 3GZHA 3UNVA 1U15A 1YFMA 3KDZA 3BHGA 3TV2A 5D6BA 4V2QA 3CZOA 1GK3A 4NLEA 2E9FA 2PTQA 1GKMA 4APBA 4NSLA 2RJRA 1T6PA 3C8TA 1GK2A 1JSWA 4BAAA 2PFMA 2YIIA 2PTSA 1FUOA 1W27A 2PTRA 2J91A 1C3CA 1J3UA 1DOFA 2QVEA 3NZ4A 4EEIA 1TJWA 3RD8A 2FUSA 1FUQA 2O6YA 2O78A 2NYNA 1K62A 5EYVA 4FLCA 5EYTA 1C3UA 4CQ5A 1YFEA 4ADMA 3OCEA 1Q5NA 2O7EA 2NYFA 4C6GA 2O7BA 4HGVA 1FUPA 2X75A 4FFXA 4ADLA 1TJVA 3RRPA 1Y2MA 4EFCA 1RE5A 3E04A 1T6JA 1KQ7A 4C5RA 3QBPA 2QGAB 5F92A 1B8FA 2RJSA 2O7FA 4C5UA 3NO9A 1DCNA 2HVGA 4V2RA 1AUWA 3OCFA 3R6YA 4APAA 1TJUA 1I0AA 1YISA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4C5S A;  1EB4 A;  3GTD A;  1U16 A;  3KDY A;  5HW2 A;  1TJ7 A;  4MX2 A;  1FUR A;  1K7W A;  4BAB A;  2O7D A;  5F91 A;  1HY0 A;  1XWO A;  1HY1 A;  2VD6 A;  2OHY A;  1GKJ A;  3R6V A;  3R6Q A;  1VDK A;  3GZH A;  3UNV A;  1U15 A;  1YFM A;  3KDZ A;  3BHG A;  3TV2 A;  5D6B A;  4V2Q A;  3CZO A;  1GK3 A;  4NLE A;  2E9F A;  2PTQ A;  1GKM A;  4APB A;  4NSL A;  2RJR A;  1T6P A;  3C8T A;  1GK2 A;  1JSW A;  4BAA A;  2PFM A;  2YII A;  2PTS A;  1FUO A;  1W27 A;  2PTR A;  2J91 A;  1C3C A;  1J3U A;  1DOF A;  2QVE A;  3NZ4 A;  4EEI A;  1TJW A;  3RD8 A;  2FUS A;  1FUQ A;  2O6Y A;  2O78 A;  2NYN A;  1K62 A;  5EYV A;  4FLC A;  5EYT A;  1C3U A;  4CQ5 A;  1YFE A;  4ADM A;  3OCE A;  1Q5N A;  2O7E A;  2NYF A;  4C6G A;  2O7B A;  4HGV A;  1FUP A;  2X75 A;  4FFX A;  4ADL A;  1TJV A;  3RRP A;  1Y2M A;  4EFC A;  1RE5 A;  3E04 A;  1T6J A;  1KQ7 A;  4C5R A;  3QBP A;  2QGA B;  5F92 A;  1B8F A;  2RJS A;  2O7F A;  4C5U A;  3NO9 A;  1DCN A;  2HVG A;  4V2R A;  1AUW A;  3OCF A;  3R6Y A;  4APA A;  1TJU A;  1I0A A;  1YIS A; 
#chains in the Genus database with same CATH topology
 4C5S A;  1EB4 A;  1TWC A;  2A6H D;  1U16 A;  2VUM A;  3GTD A;  3GTL A;  3KDY A;  5HW2 A;  1TJ7 A;  4MX2 A;  1FUR A;  1K7W A;  4BAB A;  2K3N A;  2O7D A;  3GTK A;  2EZA A;  2NVY A;  2JA6 A;  5F91 A;  2NVX A;  1HY0 A;  1XWO A;  1HY1 A;  2X0O A;  2VD6 A;  3LR2 A;  2OHY A;  1GKJ A;  3R6V A;  2BE5 D;  3R6Q A;  1XLY A;  1VDK A;  1K83 A;  3GZH A;  3UNV A;  1I0A A;  1IW7 D;  3LR6 A;  3LR8 A;  2MQA A;  1SMY D;  1ZYR D;  1EZB A;  1U15 A;  2HRO A;  1YFM A;  3BHG A;  3CRV A;  3KDZ A;  3CRW 1;  3TV2 A;  5D6B A;  2CW0 D;  2K3Q A;  3EZB A;  4V2Q A;  2LPI A;  3CQZ A;  1GK3 A;  3CZO A;  4NLE A;  2E2H A;  2E9F A;  1SFO A;  2PTQ A;  1GKM A;  4APB A;  4NSL A;  2A69 D;  2VK9 A;  2RJR A;  1T6P A;  1I3Q A;  5IZ2 A;  2AQL A;  3C8T A;  2LPJ A;  1GK2 A;  1Y1V A;  1JSW A;  4BAA A;  2PFM A;  2YII A;  3GTM A;  4A15 A;  5H8W A;  2MX9 A;  2PTS A;  1FUO A;  1W27 A;  3EZA A;  2PTR A;  4C2M A;  2J91 A;  3GTQ A;  3GTJ A;  1C3C A;  4CEJ A;  1J3U A;  1DOF A;  2A6E D;  2LKM B;  2HWG A;  2QVE A;  3NZ4 A;  3FKI A;  1I6V D;  4EEI A;  1TJW A;  3GTO A;  3RD8 A;  2FUS A;  1FUQ A;  1TWH A;  2VSF A;  2LTH A;  1XMD A;  4WNL A;  2O6Y A;  2N3E A;  1I50 A;  2O78 A;  2NYN A;  2R7Z A;  2FEL A;  2N1D B;  2E2I A;  1K62 A;  4CEH A;  5EYV A;  4FLC A;  1YNJ D;  2VL7 A;  5EYT A;  1C3U A;  4CQ5 A;  1YFE A;  2K3O A;  1TWA A;  4ADM A;  5M0J A;  2FIO A;  3OCE A;  1WCM A;  3U4Q A;  2JA7 A;  1Q5N A;  1HQM D;  2O7E A;  2NYF A;  4C6G A;  1XL8 A;  2O7B A;  4HGV A;  1FUP A;  2X75 A;  1TWF A;  4FFX A;  2R92 A;  4ADL A;  2B63 A;  1TJV A;  3RRP A;  1Y2M A;  4EFC A;  2X0P A;  1RE5 A;  3E04 A;  1T6J A;  1YNN D;  1KQ7 A;  3GTG A;  2EZB A;  2F5J A;  2MP0 A;  2X0Q A;  4C5R A;  1XL7 A;  3QBP A;  4CEI A;  2LYI A;  2R93 A;  2QGA B;  3LRD A;  2JA5 A;  5F92 A;  2FEN A;  2EZC A;  1B8F A;  5M0I A;  2YU9 A;  2RJS A;  2O7F A;  4C5U A;  3U44 A;  2O5J D;  1XMC A;  2MX8 A;  1TWG A;  3NO9 A;  4QIW A;  1DCN A;  3H0G A;  4FBS A;  3GTP A;  4V2R A;  1EZA A;  1Y1W A;  1AUW A;  2HVG A;  3OCF A;  3R6Y A;  4APA A;  2Y0N A;  1R9T A;  1TJU A;  2A68 D;  2FIP A;  1ZYM A;  1YIS A;  3EZE A; 
#chains in the Genus database with same CATH homology
 4C5S A;  1EB4 A;  3GTD A;  1U16 A;  3KDY A;  5HW2 A;  1TJ7 A;  4MX2 A;  1FUR A;  1K7W A;  4BAB A;  2O7D A;  5F91 A;  1HY0 A;  1XWO A;  1HY1 A;  2VD6 A;  2OHY A;  1GKJ A;  3R6V A;  3R6Q A;  1VDK A;  3GZH A;  3UNV A;  1U15 A;  1YFM A;  3KDZ A;  3BHG A;  3TV2 A;  5D6B A;  4V2Q A;  3CZO A;  1GK3 A;  4NLE A;  2E9F A;  2PTQ A;  1GKM A;  4APB A;  4NSL A;  2RJR A;  1T6P A;  3C8T A;  1GK2 A;  1JSW A;  4BAA A;  2PFM A;  2YII A;  2PTS A;  1FUO A;  1W27 A;  2PTR A;  2J91 A;  1C3C A;  1J3U A;  1DOF A;  2QVE A;  3NZ4 A;  4EEI A;  1TJW A;  3RD8 A;  2FUS A;  1FUQ A;  2O6Y A;  2O78 A;  2NYN A;  1K62 A;  5EYV A;  4FLC A;  5EYT A;  1C3U A;  4CQ5 A;  1YFE A;  4ADM A;  3OCE A;  1Q5N A;  2O7E A;  2NYF A;  4C6G A;  2O7B A;  4HGV A;  1FUP A;  2X75 A;  4FFX A;  4ADL A;  1TJV A;  3RRP A;  1Y2M A;  4EFC A;  1RE5 A;  3E04 A;  1T6J A;  1KQ7 A;  4C5R A;  3QBP A;  2QGA B;  5F92 A;  1B8F A;  2RJS A;  2O7F A;  4C5U A;  3NO9 A;  1DCN A;  2HVG A;  4V2R A;  1AUW A;  3OCF A;  3R6Y A;  4APA A;  1TJU A;  1I0A A;  1YIS A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...