2EZAA

Amino terminal domain of enzyme i from escherichia coli, nmr, restrained regularized mean structure
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
259
structure length
259
Chain Sequence
MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRAVQEQVASEKAELAKLKDR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Phosphotransferase
molecule keywords PHOSPHOTRANSFERASE SYSTEM, ENZYME I
publication title Defining long range order in NMR structure determination from the dependence of heteronuclear relaxation times on rotational diffusion anisotropy.
pubmed doi rcsb
source organism Escherichia coli
total genus 74
structure length 259
sequence length 259
ec nomenclature ec 2.7.3.9: Phosphoenolpyruvate--protein phosphotransferase.
pdb deposition date 1997-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00391 PEP-utilizers PEP-utilising enzyme, mobile domain
A PF05524 PEP-utilisers_N PEP-utilising enzyme, N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.10 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 PtsI, HPr-binding domain 2ezaA02
3.50.30.10 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Phosphohistidine domain 2ezaA01
2E28A 3T0TA 2R82A 2MP0A 3EZAA 2HROA 3T07A 1VBGA 2FM4A 2DIKA 5JVLA 3EZBA 2EZCA 1JDEA 2HI6A 2OLSA 3T05A 1DIKA 1EZAA 1ZYMA 1GGOA 1KBLA 1EZBA 1KC7A 2EZAA 2EZBA 2X0SA 2HWGA 1VBHA 3EZEA
chains in the Genus database with same CATH superfamily
1YNND 2MP0A 3T07A 4OC1A 2N1DB 4C8FA 4C6GA 3SJFA 4C9UA 1TWFA 4E5SA 3GTMA 2JA5A 4C9AA 2AQLA 4NGTA 4C8PA 4NGMA 1TWHA 2XEIA 3I74A 1DIKA 2X0QA 3TLGA 2O5JD 3GTPA 1T6JA 2EK9A 2PCNA 4OC4A 4C8AA 1TWGA 4CDJA 2EZCA 3D7GA 1Y1VA 1GGOA 2JBKA 4COGA 4C9RA 1TWAA 4CDKA 2E2IA 2E28A 4C99A 2K3QA 1CE8B 2CIJA 1C3OB 4YN3A 2AUMA 1Q5XA 3BI0A 4JZ0A 2EZAA 4C8UA 4W9YA 3U1BA 2C5QA 5F1YA 3S9MA 2GP4A 3U44A 3ICUA 2PVVA 2A6HD 2R92A 2K3NA 1SMYD 3NOJA 4TWEA 1Y1WA 1KC7A 3LRDA 1T6PA 1ZYRD 4OC3A 3KASA 4C8CA 3BI1A 4C5SA 2PVWA 2VK9A 2D0PA 4INJA 2A69D 3D7FA 3GTGA 1JDEA 1ZRSA 4M8DA 4MI1A 3C8OA 1SFOA 3RBUA 3K4IA 2C6PA 3U4QA 3NZ4A 1C30B 2CW0D 4NGNA 2FIOA 4X3RA 3GTQA 2MX8A 3S9LA 4MCRA 1Y9ZA 2C6GA 4COBA 1W27A 2LPJA 4C9EA 2A6ED 2LPIA 3T05A 4P4FA 4CEHA 4P4JA 2LYIA 1I3QA 2MX9A 5F9MA 5IB9A 3T0TA 2FIPA 3LR2A 2AUNA 2FM4A 3TLZA 2X0OA 3TLYA 3GTOA 3TLCA 4CEJA 1CS0B 2YIIA 4MCSA 3GTKA 3TYXA 2R7ZA 2LKMB 1WVMA 2JBJA 4V2QA 2B0AA 2E2HA 4C8TA 1ZL0A 5IR2A 4P4IA 4TJVA 3KRVA 1KBLA 3FEDA 3GTLA 2LTHA 4CQ5A 1R61A 3LR6A 2XEFA 2R82A 5JYBA 1V6CA 4CZ1A 3BXMA 4V2RA 2YJVA 1JDBC 1WCMA 2B63A 4H1HA 3FEEA 4C85A 2HI6A 2JA7A 2OR4A 4CEIA 1IW7D 5K99A 4C84A 1NBWA 1TWCA 4MCPA 4BAAA 1YNJD 3TLEA 4P4BA 3GTJA 2K3OA 4BABA 1HQMD 4C5UA 3EZBA 3SJGA 3LR8A 2A68D 3FKIA 1DE4C 1Z8LA 4J0NA 5D29A 2MQAA 1K83A 1EZAA 1I50A 2C6CA 1Y2MA 2JA6A 2HWGA 3IIBA 1I6VD 2YJTA 2D0OA 4KNGE 3SR3A 5JVLA 4P44A 4C5RA 1T36B 1EZBA 4LQGA 1R9TA 2NVYA 4P4DA 5FD8A 2VUMA 2X0SA 3EZAA 2YU9A 2OOTA 4JVOA 4MCQA 3H0GA 2F5JA 4FBSA 4P4EA 4TJXA 3I6SA 4NGRA 4C86A 3G23A 3D7DA 2X0PA 4QIWA 4IIXA 4OC0A 4E94A 1VBGA 2R93A 1BXRB 3CQZA 2EK8A 5F09A 1M6VB 3FECA 2NVXA 1ZYMA 1CX8A 3K9TA 5ELYA 1J3LA 1KEEB 2EZBA 3SJEA 3TLAA 3T5MA 2BE5D 2Y0NA 3IWWA 4NGQA 3TLBA 1NXJA 3VTAA 5IZ2A 3EIFA 2OLSA 3SJXA 4JYWA 4NGPA 4OC5A 4C9VA 4NGSA 5F5XA 3GJZA 4CO9A 2XEJA 1A9XB 3BHXA 2HROA 4C2MA 3D7HA 3FF3A 2DIKA 3TLGB 4OMEA 1XF1A 2N3EA 3S9NA 4OC2A 4MJXA 4IIYA 4EYSA 2XEGA 4P45A 1VBHA 3EZEA 1VI4A
chains in the Genus database with same CATH topology
2E28A 3T0TA 2R82A 2MP0A 3EZAA 2HROA 3T07A 1VBGA 2FM4A 2DIKA 5JVLA 3EZBA 2EZCA 1JDEA 2HI6A 2OLSA 3T05A 1DIKA 1EZAA 1ZYMA 1GGOA 1KBLA 1EZBA 1KC7A 2EZAA 2EZBA 2X0SA 2HWGA 1VBHA 3EZEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2E28 A;  3T0T A;  2R82 A;  2MP0 A;  3EZA A;  2HRO A;  3T07 A;  1VBG A;  2FM4 A;  2DIK A;  5JVL A;  3EZB A;  2EZC A;  1JDE A;  2HI6 A;  2OLS A;  3T05 A;  1DIK A;  1EZA A;  1ZYM A;  1GGO A;  1KBL A;  1EZB A;  1KC7 A;  2EZA A;  2EZB A;  2X0S A;  2HWG A;  1VBH A;  3EZE A; 
#chains in the Genus database with same CATH topology
 1YNN D;  2MP0 A;  3T07 A;  4OC1 A;  2N1D B;  4C8F A;  4C6G A;  3SJF A;  4C9U A;  1TWF A;  4E5S A;  3GTM A;  2JA5 A;  4C9A A;  2AQL A;  4NGT A;  4C8P A;  4NGM A;  1TWH A;  2XEI A;  3I74 A;  1DIK A;  2X0Q A;  3TLG A;  2O5J D;  3GTP A;  1T6J A;  2EK9 A;  2PCN A;  4OC4 A;  4C8A A;  1TWG A;  4CDJ A;  2EZC A;  3D7G A;  1Y1V A;  1GGO A;  2JBK A;  4COG A;  4C9R A;  1TWA A;  4CDK A;  2E2I A;  2E28 A;  4C99 A;  2K3Q A;  1CE8 B;  2CIJ A;  1C3O B;  4YN3 A;  2AUM A;  1Q5X A;  3BI0 A;  4JZ0 A;  2EZA A;  4C8U A;  4W9Y A;  3U1B A;  2C5Q A;  5F1Y A;  3S9M A;  2GP4 A;  3U44 A;  3ICU A;  2PVV A;  2A6H D;  2R92 A;  2K3N A;  1SMY D;  3NOJ A;  4TWE A;  1Y1W A;  1KC7 A;  3LRD A;  1T6P A;  1ZYR D;  4OC3 A;  3KAS A;  4C8C A;  3BI1 A;  4C5S A;  2PVW A;  2VK9 A;  2D0P A;  4INJ A;  2A69 D;  3D7F A;  3GTG A;  1JDE A;  1ZRS A;  4M8D A;  4MI1 A;  3C8O A;  1SFO A;  3RBU A;  3K4I A;  2C6P A;  3U4Q A;  3NZ4 A;  1C30 B;  2CW0 D;  4NGN A;  2FIO A;  4X3R A;  3GTQ A;  2MX8 A;  3S9L A;  4MCR A;  1Y9Z A;  2C6G A;  4COB A;  1W27 A;  2LPJ A;  4C9E A;  2A6E D;  2LPI A;  3T05 A;  4P4F A;  4CEH A;  4P4J A;  2LYI A;  1I3Q A;  2MX9 A;  5F9M A;  5IB9 A;  3T0T A;  2FIP A;  3LR2 A;  2AUN A;  2FM4 A;  3TLZ A;  2X0O A;  3TLY A;  3GTO A;  3TLC A;  4CEJ A;  1CS0 B;  2YII A;  4MCS A;  3GTK A;  3TYX A;  2R7Z A;  2LKM B;  1WVM A;  2JBJ A;  4V2Q A;  2B0A A;  2E2H A;  4C8T A;  1ZL0 A;  5IR2 A;  4P4I A;  4TJV A;  3KRV A;  1KBL A;  3FED A;  3GTL A;  2LTH A;  4CQ5 A;  1R61 A;  3LR6 A;  2XEF A;  2R82 A;  5JYB A;  1V6C A;  4CZ1 A;  3BXM A;  4V2R A;  2YJV A;  1JDB C;  1WCM A;  2B63 A;  4H1H A;  3FEE A;  4C85 A;  2HI6 A;  2JA7 A;  2OR4 A;  4CEI A;  1IW7 D;  5K99 A;  4C84 A;  1NBW A;  1TWC A;  4MCP A;  4BAA A;  1YNJ D;  3TLE A;  4P4B A;  3GTJ A;  2K3O A;  4BAB A;  1HQM D;  4C5U A;  3EZB A;  3SJG A;  3LR8 A;  2A68 D;  3FKI A;  1DE4 C;  1Z8L A;  4J0N A;  5D29 A;  2MQA A;  1K83 A;  1EZA A;  1I50 A;  2C6C A;  1Y2M A;  2JA6 A;  2HWG A;  3IIB A;  1I6V D;  2YJT A;  2D0O A;  4KNG E;  3SR3 A;  5JVL A;  4P44 A;  4C5R A;  1T36 B;  1EZB A;  4LQG A;  1R9T A;  2NVY A;  4P4D A;  5FD8 A;  2VUM A;  2X0S A;  3EZA A;  2YU9 A;  2OOT A;  4JVO A;  4MCQ A;  3H0G A;  2F5J A;  4FBS A;  4P4E A;  4TJX A;  3I6S A;  4NGR A;  4C86 A;  3G23 A;  3D7D A;  2X0P A;  4QIW A;  4IIX A;  4OC0 A;  4E94 A;  1VBG A;  2R93 A;  1BXR B;  3CQZ A;  2EK8 A;  5F09 A;  1M6V B;  3FEC A;  2NVX A;  1ZYM A;  1CX8 A;  3K9T A;  5ELY A;  1J3L A;  1KEE B;  2EZB A;  3SJE A;  3TLA A;  3T5M A;  2BE5 D;  2Y0N A;  3IWW A;  4NGQ A;  3TLB A;  1NXJ A;  3VTA A;  5IZ2 A;  3EIF A;  2OLS A;  3SJX A;  4JYW A;  4NGP A;  4OC5 A;  4C9V A;  4NGS A;  5F5X A;  3GJZ A;  4CO9 A;  2XEJ A;  1A9X B;  3BHX A;  2HRO A;  4C2M A;  3D7H A;  3FF3 A;  2DIK A;  3TLG B;  4OME A;  1XF1 A;  2N3E A;  3S9N A;  4OC2 A;  4MJX A;  4IIY A;  4EYS A;  2XEG A;  4P45 A;  1VBH A;  3EZE A;  1VI4 A; 
#chains in the Genus database with same CATH homology
 2E28 A;  3T0T A;  2R82 A;  2MP0 A;  3EZA A;  2HRO A;  3T07 A;  1VBG A;  2FM4 A;  2DIK A;  5JVL A;  3EZB A;  2EZC A;  1JDE A;  2HI6 A;  2OLS A;  3T05 A;  1DIK A;  1EZA A;  1ZYM A;  1GGO A;  1KBL A;  1EZB A;  1KC7 A;  2EZA A;  2EZB A;  2X0S A;  2HWG A;  1VBH A;  3EZE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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