2EZAA

Amino terminal domain of enzyme i from escherichia coli, nmr, restrained regularized mean structure
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
259
structure length
259
Chain Sequence
MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRAVQEQVASEKAELAKLKDR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords PHOSPHOTRANSFERASE SYSTEM, ENZYME I
publication title Defining long range order in NMR structure determination from the dependence of heteronuclear relaxation times on rotational diffusion anisotropy.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Phosphotransferase
total genus 74
structure length 259
sequence length 259
ec nomenclature ec 2.7.3.9: Phosphoenolpyruvate--protein phosphotransferase.
pdb deposition date 1997-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00391 PEP-utilizers PEP-utilising enzyme, mobile domain
A PF05524 PEP-utilisers_N PEP-utilising enzyme, N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.10 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 PtsI, HPr-binding domain 2ezaA02
3.50.30.10 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Phosphohistidine domain 2ezaA01
1ZYMA 2HROA 1DIKA 1VBGA 1VBHA 2MP0A 1KBLA 2X0SA 1EZBA 2FM4A 1GGOA 1KC7A 2R82A 2HI6A 2OLSA 3EZAA 1EZAA 3T0TA 2EZCA 2HWGA 3T05A 2EZAA 2E28A 3EZEA 3EZBA 2DIKA 1JDEA 3T07A 5JVLA 2EZBA
chains in the Genus database with same CATH superfamily
1W27A 1NBWA 3D7FA 4INJA 2C6PA 2FIPA 4MCRA 4NGSA 3S9NA 2X0SA 3FEDA 4COBA 3LR6A 4QIWA 2A69D 2Y0NA 2D0OA 4C86A 2E2HA 2DIKA 3TLCA 3KRVA 4MCPA 3NZ4A 2YJTA 3GTOA 3LR8A 4C9RA 4JZ0A 1ZL0A 3ICUA 4OC0A 5F5XA 2OR4A 5IZ2A 3IIBA 1VBGA 4OC4A 3GTKA 2OOTA 4MCSA 4P45A 1KC7A 3BI0A 2O5JD 4P4BA 2F5JA 2B63A 1YNJD 4C8CA 4OC2A 3U44A 4EYSA 2MX9A 2MX8A 3TLEA 1K83A 2FM4A 3TLAA 2JA6A 5JYBA 3T5MA 1NXJA 3LRDA 3BXMA 2PVWA 2X0PA 2YIIA 1Y1WA 1ZRSA 1ZYMA 4J0NA 1A9XB 3U4QA 4E5SA 4C85A 3K9TA 1Y1VA 1XF1A 2EK8A 1TWCA 1EZAA 3IWWA 1M6VB 4C9EA 1V6CA 3CQZA 1DE4C 3FKIA 5JVLA 1SMYD 4OMEA 5K99A 1CX8A 4X3RA 4NGNA 1EZBA 3BI1A 4OC3A 4OC1A 2NVXA 2XEGA 2C6GA 4M8DA 3GTLA 4MCQA 3T05A 3H0GA 4BABA 2JA5A 2JBKA 3SJGA 4H1HA 4CEHA 3VTAA 2LTHA 2JBJA 4C5SA 3RBUA 2K3NA 4CEIA 2X0QA 2CW0D 2HI6A 4CZ1A 2A68D 3TLYA 2FIOA 2R93A 1YNND 4KNGE 1J3LA 4NGMA 4C5RA 2VUMA 4P44A 2EZBA 2EK9A 1Q5XA 1KBLA 2K3QA 2NVYA 3G23A 4C8UA 1ZYRD 3C8OA 3LR2A 3D7GA 2D0PA 1T6JA 2LPJA 3SJXA 4V2QA 4C8TA 3GJZA 5D29A 4P4IA 3S9LA 1CE8B 1I3QA 2B0AA 2N1DB 4CQ5A 2E2IA 1WCMA 3T0TA 2LPIA 2CIJA 3TLZA 3GTMA 2EZAA 3EZEA 3EZBA 1KEEB 1Z8LA 4CO9A 2VK9A 4OC5A 2MP0A 2K3OA 3I6SA 1SFOA 4NGPA 3GTGA 4LQGA 3FEEA 4W9YA 2C5QA 1Y2MA 2HWGA 2AUNA 2C6CA 5IR2A 2A6HD 3TLBA 2HROA 1R61A 1VBHA 4P4EA 5F9MA 3TLGA 4NGRA 4CDKA 3GTJA 2XEIA 3K4IA 2R82A 4NGTA 2OLSA 3TYXA 2EZCA 4NGQA 1I6VD 1IW7D 3FECA 4C84A 2LYIA 2YJVA 2LKMB 4V2RA 4C9AA 3SJFA 1C30B 2MQAA 3D7DA 4C9UA 4C8AA 4C6GA 1I50A 3SR3A 5F09A 4C8PA 1TWFA 1VI4A 1TWAA 3TLGB 3EIFA 4E94A 1T36B 1WVMA 4C99A 4YN3A 1TWHA 4C8FA 2X0OA 1DIKA 4P4FA 4BAAA 1TWGA 5FD8A 1HQMD 2R92A 2N3EA 4IIXA 3EZAA 4C9VA 2PCNA 2R7ZA 1R9TA 2A6ED 5ELYA 2PVVA 4MJXA 3D7HA 1GGOA 2XEFA 1Y9ZA 1CS0B 3S9MA 2AUMA 5IB9A 4TJVA 2E28A 4IIYA 2BE5D 4TWEA 3SJEA 3GTPA 3KASA 3GTQA 2GP4A 4C5UA 1T6PA 4COGA 1BXRB 4CDJA 3FF3A 3U1BA 1C3OB 2AQLA 3BHXA 2JA7A 1JDEA 4MI1A 3T07A 4FBSA 1JDBC 4CEJA 4TJXA 5F1YA 2XEJA 4C2MA 4P4JA 2YU9A 4JVOA 3I74A 4P4DA 4JYWA 3NOJA
chains in the Genus database with same CATH topology
1ZYMA 2HROA 1DIKA 1VBGA 1VBHA 2MP0A 1KBLA 2X0SA 1EZBA 2FM4A 1GGOA 1KC7A 2R82A 2HI6A 2OLSA 3EZAA 1EZAA 3T0TA 2EZCA 2HWGA 3T05A 2EZAA 2E28A 3EZEA 3EZBA 2DIKA 1JDEA 3T07A 5JVLA 2EZBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZYM A;  2HRO A;  1DIK A;  1VBG A;  1VBH A;  2MP0 A;  1KBL A;  2X0S A;  1EZB A;  2FM4 A;  1GGO A;  1KC7 A;  2R82 A;  2HI6 A;  2OLS A;  3EZA A;  1EZA A;  3T0T A;  2EZC A;  2HWG A;  3T05 A;  2EZA A;  2E28 A;  3EZE A;  3EZB A;  2DIK A;  1JDE A;  3T07 A;  5JVL A;  2EZB A; 
#chains in the Genus database with same CATH topology
 1W27 A;  1NBW A;  3D7F A;  4INJ A;  2C6P A;  2FIP A;  4MCR A;  4NGS A;  3S9N A;  2X0S A;  3FED A;  4COB A;  3LR6 A;  4QIW A;  2A69 D;  2Y0N A;  2D0O A;  4C86 A;  2E2H A;  2DIK A;  3TLC A;  3KRV A;  4MCP A;  3NZ4 A;  2YJT A;  3GTO A;  3LR8 A;  4C9R A;  4JZ0 A;  1ZL0 A;  3ICU A;  4OC0 A;  5F5X A;  2OR4 A;  5IZ2 A;  3IIB A;  1VBG A;  4OC4 A;  3GTK A;  2OOT A;  4MCS A;  4P45 A;  1KC7 A;  3BI0 A;  2O5J D;  4P4B A;  2F5J A;  2B63 A;  1YNJ D;  4C8C A;  4OC2 A;  3U44 A;  4EYS A;  2MX9 A;  2MX8 A;  3TLE A;  1K83 A;  2FM4 A;  3TLA A;  2JA6 A;  5JYB A;  3T5M A;  1NXJ A;  3LRD A;  3BXM A;  2PVW A;  2X0P A;  2YII A;  1Y1W A;  1ZRS A;  1ZYM A;  4J0N A;  1A9X B;  3U4Q A;  4E5S A;  4C85 A;  3K9T A;  1Y1V A;  1XF1 A;  2EK8 A;  1TWC A;  1EZA A;  3IWW A;  1M6V B;  4C9E A;  1V6C A;  3CQZ A;  1DE4 C;  3FKI A;  5JVL A;  1SMY D;  4OME A;  5K99 A;  1CX8 A;  4X3R A;  4NGN A;  1EZB A;  3BI1 A;  4OC3 A;  4OC1 A;  2NVX A;  2XEG A;  2C6G A;  4M8D A;  3GTL A;  4MCQ A;  3T05 A;  3H0G A;  4BAB A;  2JA5 A;  2JBK A;  3SJG A;  4H1H A;  4CEH A;  3VTA A;  2LTH A;  2JBJ A;  4C5S A;  3RBU A;  2K3N A;  4CEI A;  2X0Q A;  2CW0 D;  2HI6 A;  4CZ1 A;  2A68 D;  3TLY A;  2FIO A;  2R93 A;  1YNN D;  4KNG E;  1J3L A;  4NGM A;  4C5R A;  2VUM A;  4P44 A;  2EZB A;  2EK9 A;  1Q5X A;  1KBL A;  2K3Q A;  2NVY A;  3G23 A;  4C8U A;  1ZYR D;  3C8O A;  3LR2 A;  3D7G A;  2D0P A;  1T6J A;  2LPJ A;  3SJX A;  4V2Q A;  4C8T A;  3GJZ A;  5D29 A;  4P4I A;  3S9L A;  1CE8 B;  1I3Q A;  2B0A A;  2N1D B;  4CQ5 A;  2E2I A;  1WCM A;  3T0T A;  2LPI A;  2CIJ A;  3TLZ A;  3GTM A;  2EZA A;  3EZE A;  3EZB A;  1KEE B;  1Z8L A;  4CO9 A;  2VK9 A;  4OC5 A;  2MP0 A;  2K3O A;  3I6S A;  1SFO A;  4NGP A;  3GTG A;  4LQG A;  3FEE A;  4W9Y A;  2C5Q A;  1Y2M A;  2HWG A;  2AUN A;  2C6C A;  5IR2 A;  2A6H D;  3TLB A;  2HRO A;  1R61 A;  1VBH A;  4P4E A;  5F9M A;  3TLG A;  4NGR A;  4CDK A;  3GTJ A;  2XEI A;  3K4I A;  2R82 A;  4NGT A;  2OLS A;  3TYX A;  2EZC A;  4NGQ A;  1I6V D;  1IW7 D;  3FEC A;  4C84 A;  2LYI A;  2YJV A;  2LKM B;  4V2R A;  4C9A A;  3SJF A;  1C30 B;  2MQA A;  3D7D A;  4C9U A;  4C8A A;  4C6G A;  1I50 A;  3SR3 A;  5F09 A;  4C8P A;  1TWF A;  1VI4 A;  1TWA A;  3TLG B;  3EIF A;  4E94 A;  1T36 B;  1WVM A;  4C99 A;  4YN3 A;  1TWH A;  4C8F A;  2X0O A;  1DIK A;  4P4F A;  4BAA A;  1TWG A;  5FD8 A;  1HQM D;  2R92 A;  2N3E A;  4IIX A;  3EZA A;  4C9V A;  2PCN A;  2R7Z A;  1R9T A;  2A6E D;  5ELY A;  2PVV A;  4MJX A;  3D7H A;  1GGO A;  2XEF A;  1Y9Z A;  1CS0 B;  3S9M A;  2AUM A;  5IB9 A;  4TJV A;  2E28 A;  4IIY A;  2BE5 D;  4TWE A;  3SJE A;  3GTP A;  3KAS A;  3GTQ A;  2GP4 A;  4C5U A;  1T6P A;  4COG A;  1BXR B;  4CDJ A;  3FF3 A;  3U1B A;  1C3O B;  2AQL A;  3BHX A;  2JA7 A;  1JDE A;  4MI1 A;  3T07 A;  4FBS A;  1JDB C;  4CEJ A;  4TJX A;  5F1Y A;  2XEJ A;  4C2M A;  4P4J A;  2YU9 A;  4JVO A;  3I74 A;  4P4D A;  4JYW A;  3NOJ A; 
#chains in the Genus database with same CATH homology
 1ZYM A;  2HRO A;  1DIK A;  1VBG A;  1VBH A;  2MP0 A;  1KBL A;  2X0S A;  1EZB A;  2FM4 A;  1GGO A;  1KC7 A;  2R82 A;  2HI6 A;  2OLS A;  3EZA A;  1EZA A;  3T0T A;  2EZC A;  2HWG A;  3T05 A;  2EZA A;  2E28 A;  3EZE A;  3EZB A;  2DIK A;  1JDE A;  3T07 A;  5JVL A;  2EZB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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