4CQ5A

Structural investigations into the stereochemistry and activity of a phenylalanine-2,3-aminomutase from taxus chinensis
Total Genus 268
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
268
sequence length
667
structure length
638
Chain Sequence
SHVKDILGLINAFNEVKKITVDGTTPITVAHVAALARRHDVKVALEAEQCRARVETCSSWVQRKAEDGADIAGVTTGFGACSSRRTNRLSELQESLIRCLLAGVFTLPATATRSAMLLRLNSFTYGCSGIRWEVMEALEKLLNSNVSPKVPLRGSVSDLIPLAYIAGLLIGKPSVIARIGDDVEVPAPEALSRVGLRPFKLQAKEGLALVNGTSFATAVASTVMYDANVLLLLVETLCGMFCEVIFGREEFAHPLIHKVKPHPGQIESAELLEWLLRSSPFQELSREYYSIDKLKKPKQDRYALRSSPQWLAPLVQTIRDATTTVETEVNSANDNPIIDHANDRALHGANFQGSAVGFYMDYVRIAVAGLGKLLFAQFTELMIEYYSNGLPGNLSLGPDLSVDYGLKGLDIAMAAYSSELQYLANPVTTHVHSAEQHNQDINSLALISARKTEEALDILKLMIASHLTAMCQAVDLRQLEEALVKVVENVVSTLADECGLPNDTKARLLYVAKAVPVYTYLESPCDPTLPLLLGLKQSCFDTILALHDTLVDRLAEFEKRLSDRLENEMTAVRVLYEKVRIQGSKFLPFYRFVREELDTGVMSARREQTPQEDVQKVFDAIADGRITVPLLHCLQGFL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Investigations Into the Stereochemistry and Activity of a Phenylalanine-2,3-Aminomutase from Taxus Chinensis.
pubmed doi rcsb
source organism Taxus wallichiana var. chinensis
molecule tags Lyase
molecule keywords PHENYLALANINE AMINOMUTASE
total genus 268
structure length 638
sequence length 667
chains with identical sequence B, C, D
ec nomenclature ec 4.3.1.24: Phenylalanine ammonia-lyase.
pdb deposition date 2014-02-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.20 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 Phenylalanine ammonia-lyase 1; domain 3 4cq5A03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 4cq5A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 4cq5A02
3C8TA 2YIIA 2PTSA 2HVGA 1T6JA 1DOFA 4BABA 3R6VA 4BAAA 2NYFA 4FFXA 2O78A 1JSWA 5F92A 1GK3A 1FUQA 2FUSA 1C3CA 4C5SA 4EEIA 1TJVA 4C6GA 2X75A 1XWOA 1K7WA 2PTQA 1RE5A 1U16A 3NZ4A 1Q5NA 1YFMA 3QBPA 3GZHA 1B8FA 4V2RA 1EB4A 5EYVA 1GK2A 3KDYA 1YISA 1W27A 4NLEA 2OHYA 3NO9A 2O7EA 3OCFA 1C3UA 4HGVA 1FUPA 3GTDA 3CZOA 2QVEA 4FLCA 3OCEA 3R6YA 1T6PA 4NSLA 1TJUA 5F91A 2PTRA 1HY1A 2NYNA 4C5RA 2J91A 3KDZA 4V2QA 2O7DA 3RD8A 1Y2MA 3BHGA 4C5UA 1YFEA 1J3UA 4APBA 1K62A 1FURA 2QGAB 5EYTA 4CQ5A 5D6BA 4MX2A 3UNVA 2VD6A 1TJ7A 1FUOA 3R6QA 1KQ7A 2PFMA 1TJWA 4ADLA 1DCNA 4ADMA 1GKJA 2O7FA 3RRPA 4EFCA 3TV2A 1U15A 2O6YA 4APAA 1GKMA 2O7BA 1VDKA 1HY0A 2RJSA 2E9FA 5HW2A 1AUWA 3E04A 2RJRA 1I0AA
chains in the Genus database with same CATH superfamily
3C8TA 2YIIA 2K3NA 2PTSA 2LPJA 4C2MA 3EZEA 2HVGA 1T6JA 1EZBA 1IW7D 1I6VD 1DOFA 3CRVA 4BABA 2FIOA 5IZ2A 3GTLA 1TWCA 1EZAA 3R6VA 4BAAA 2NYFA 3GTGA 2K3OA 2B63A 2VL7A 4FFXA 5M0JA 2O78A 2MQAA 1JSWA 3LR6A 1XL7A 3LR8A 5F92A 1GK3A 1FUQA 2FUSA 4WNLA 2MP0A 2LPIA 4C5SA 1C3CA 4EEIA 2X0OA 1TJVA 3U4QA 4C6GA 1SMYD 2X75A 1XWOA 1K7WA 1ZYRD 2R92A 2PTQA 2E2IA 2Y0NA 3CRW1 1TWHA 2YU9A 2HWGA 2R7ZA 1RE5A 1U16A 1XL8A 1XLYA 3NZ4A 1Q5NA 4FBSA 2AQLA 1YFMA 1YNJD 3H0GA 1TWFA 3QBPA 3GTQA 3GZHA 3GTKA 2F5JA 3EZAA 3GTOA 1WCMA 1TWAA 2N1DB 2FELA 3FKIA 1B8FA 4V2RA 2O5JD 1EB4A 5EYVA 1GK2A 3KDYA 1YISA 1W27A 4NLEA 5M0IA 2OHYA 3NO9A 2O7EA 1HQMD 3OCFA 1C3UA 4HGVA 1FUPA 3GTDA 4A15A 4CEHA 2LKMB 3CZOA 2QVEA 4CEJA 4FLCA 3LRDA 2N3EA 3OCEA 3R6YA 1T6PA 1Y1VA 2A68D 1TJUA 2VSFA 2PTRA 4NSLA 5F91A 2JA6A 1HY1A 3GTJA 2BE5D 2X0QA 4C5RA 3U44A 2NYNA 2J91A 3KDZA 4V2QA 5H8WA 2O7DA 3RD8A 1Y2MA 1SFOA 3BHGA 4C5UA 1YFEA 1J3UA 4APBA 2LTHA 1K62A 1FURA 2QGAB 5EYTA 2X0PA 3EZBA 4CQ5A 5D6BA 2E2HA 4MX2A 3GTMA 1Y1WA 1XMDA 2CW0D 3UNVA 1I50A 2MX8A 2VD6A 1TJ7A 2LYIA 2K3QA 2A6ED 1R9TA 2FENA 1FUOA 3LR2A 2VUMA 2NVYA 3CQZA 2A69D 2NVXA 3R6QA 1KQ7A 2EZAA 1I3QA 2PFMA 1TJWA 4ADLA 1TWGA 1DCNA 4ADMA 1GKJA 2O7FA 4CEIA 1ZYMA 3RRPA 3TV2A 3GTPA 4EFCA 2VK9A 1U15A 2O6YA 2JA7A 4APAA 1GKMA 2A6HD 2O7BA 2R93A 2MX9A 1XMCA 2EZBA 1VDKA 1HY0A 2JA5A 1YNND 2RJSA 2HROA 2E9FA 5HW2A 1AUWA 3E04A 1K83A 2EZCA 4QIWA 2FIPA 2RJRA 1I0AA
chains in the Genus database with same CATH topology
3C8TA 2YIIA 2PTSA 2HVGA 1T6JA 1DOFA 4BABA 3R6VA 4BAAA 2NYFA 4FFXA 2O78A 1JSWA 5F92A 1GK3A 1FUQA 2FUSA 1C3CA 4C5SA 4EEIA 1TJVA 4C6GA 2X75A 1XWOA 1K7WA 2PTQA 1RE5A 1U16A 3NZ4A 1Q5NA 1YFMA 3QBPA 3GZHA 1B8FA 4V2RA 1EB4A 5EYVA 1GK2A 3KDYA 1YISA 1W27A 4NLEA 2OHYA 3NO9A 2O7EA 3OCFA 1C3UA 4HGVA 1FUPA 3GTDA 3CZOA 2QVEA 4FLCA 3OCEA 3R6YA 1T6PA 4NSLA 1TJUA 5F91A 2PTRA 1HY1A 2NYNA 4C5RA 2J91A 3KDZA 4V2QA 2O7DA 3RD8A 1Y2MA 3BHGA 4C5UA 1YFEA 1J3UA 4APBA 1K62A 1FURA 2QGAB 5EYTA 4CQ5A 5D6BA 4MX2A 3UNVA 2VD6A 1TJ7A 1FUOA 3R6QA 1KQ7A 2PFMA 1TJWA 4ADLA 1DCNA 4ADMA 1GKJA 2O7FA 3RRPA 4EFCA 3TV2A 1U15A 2O6YA 4APAA 1GKMA 2O7BA 1VDKA 1HY0A 2RJSA 2E9FA 5HW2A 1AUWA 3E04A 2RJRA 1I0AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3C8T A;  2YII A;  2PTS A;  2HVG A;  1T6J A;  1DOF A;  4BAB A;  3R6V A;  4BAA A;  2NYF A;  4FFX A;  2O78 A;  1JSW A;  5F92 A;  1GK3 A;  1FUQ A;  2FUS A;  1C3C A;  4C5S A;  4EEI A;  1TJV A;  4C6G A;  2X75 A;  1XWO A;  1K7W A;  2PTQ A;  1RE5 A;  1U16 A;  3NZ4 A;  1Q5N A;  1YFM A;  3QBP A;  3GZH A;  1B8F A;  4V2R A;  1EB4 A;  5EYV A;  1GK2 A;  3KDY A;  1YIS A;  1W27 A;  4NLE A;  2OHY A;  3NO9 A;  2O7E A;  3OCF A;  1C3U A;  4HGV A;  1FUP A;  3GTD A;  3CZO A;  2QVE A;  4FLC A;  3OCE A;  3R6Y A;  1T6P A;  4NSL A;  1TJU A;  5F91 A;  2PTR A;  1HY1 A;  2NYN A;  4C5R A;  2J91 A;  3KDZ A;  4V2Q A;  2O7D A;  3RD8 A;  1Y2M A;  3BHG A;  4C5U A;  1YFE A;  1J3U A;  4APB A;  1K62 A;  1FUR A;  2QGA B;  5EYT A;  4CQ5 A;  5D6B A;  4MX2 A;  3UNV A;  2VD6 A;  1TJ7 A;  1FUO A;  3R6Q A;  1KQ7 A;  2PFM A;  1TJW A;  4ADL A;  1DCN A;  4ADM A;  1GKJ A;  2O7F A;  3RRP A;  4EFC A;  3TV2 A;  1U15 A;  2O6Y A;  4APA A;  1GKM A;  2O7B A;  1VDK A;  1HY0 A;  2RJS A;  2E9F A;  5HW2 A;  1AUW A;  3E04 A;  2RJR A;  1I0A A; 
#chains in the Genus database with same CATH topology
 3C8T A;  2YII A;  2K3N A;  2PTS A;  2LPJ A;  4C2M A;  3EZE A;  2HVG A;  1T6J A;  1EZB A;  1IW7 D;  1I6V D;  1DOF A;  3CRV A;  4BAB A;  2FIO A;  5IZ2 A;  3GTL A;  1TWC A;  1EZA A;  3R6V A;  4BAA A;  2NYF A;  3GTG A;  2K3O A;  2B63 A;  2VL7 A;  4FFX A;  5M0J A;  2O78 A;  2MQA A;  1JSW A;  3LR6 A;  1XL7 A;  3LR8 A;  5F92 A;  1GK3 A;  1FUQ A;  2FUS A;  4WNL A;  2MP0 A;  2LPI A;  4C5S A;  1C3C A;  4EEI A;  2X0O A;  1TJV A;  3U4Q A;  4C6G A;  1SMY D;  2X75 A;  1XWO A;  1K7W A;  1ZYR D;  2R92 A;  2PTQ A;  2E2I A;  2Y0N A;  3CRW 1;  1TWH A;  2YU9 A;  2HWG A;  2R7Z A;  1RE5 A;  1U16 A;  1XL8 A;  1XLY A;  3NZ4 A;  1Q5N A;  4FBS A;  2AQL A;  1YFM A;  1YNJ D;  3H0G A;  1TWF A;  3QBP A;  3GTQ A;  3GZH A;  3GTK A;  2F5J A;  3EZA A;  3GTO A;  1WCM A;  1TWA A;  2N1D B;  2FEL A;  3FKI A;  1B8F A;  4V2R A;  2O5J D;  1EB4 A;  5EYV A;  1GK2 A;  3KDY A;  1YIS A;  1W27 A;  4NLE A;  5M0I A;  2OHY A;  3NO9 A;  2O7E A;  1HQM D;  3OCF A;  1C3U A;  4HGV A;  1FUP A;  3GTD A;  4A15 A;  4CEH A;  2LKM B;  3CZO A;  2QVE A;  4CEJ A;  4FLC A;  3LRD A;  2N3E A;  3OCE A;  3R6Y A;  1T6P A;  1Y1V A;  2A68 D;  1TJU A;  2VSF A;  2PTR A;  4NSL A;  5F91 A;  2JA6 A;  1HY1 A;  3GTJ A;  2BE5 D;  2X0Q A;  4C5R A;  3U44 A;  2NYN A;  2J91 A;  3KDZ A;  4V2Q A;  5H8W A;  2O7D A;  3RD8 A;  1Y2M A;  1SFO A;  3BHG A;  4C5U A;  1YFE A;  1J3U A;  4APB A;  2LTH A;  1K62 A;  1FUR A;  2QGA B;  5EYT A;  2X0P A;  3EZB A;  4CQ5 A;  5D6B A;  2E2H A;  4MX2 A;  3GTM A;  1Y1W A;  1XMD A;  2CW0 D;  3UNV A;  1I50 A;  2MX8 A;  2VD6 A;  1TJ7 A;  2LYI A;  2K3Q A;  2A6E D;  1R9T A;  2FEN A;  1FUO A;  3LR2 A;  2VUM A;  2NVY A;  3CQZ A;  2A69 D;  2NVX A;  3R6Q A;  1KQ7 A;  2EZA A;  1I3Q A;  2PFM A;  1TJW A;  4ADL A;  1TWG A;  1DCN A;  4ADM A;  1GKJ A;  2O7F A;  4CEI A;  1ZYM A;  3RRP A;  3TV2 A;  3GTP A;  4EFC A;  2VK9 A;  1U15 A;  2O6Y A;  2JA7 A;  4APA A;  1GKM A;  2A6H D;  2O7B A;  2R93 A;  2MX9 A;  1XMC A;  2EZB A;  1VDK A;  1HY0 A;  2JA5 A;  1YNN D;  2RJS A;  2HRO A;  2E9F A;  5HW2 A;  1AUW A;  3E04 A;  1K83 A;  2EZC A;  4QIW A;  2FIP A;  2RJR A;  1I0A A; 
#chains in the Genus database with same CATH homology
 3C8T A;  2YII A;  2PTS A;  2HVG A;  1T6J A;  1DOF A;  4BAB A;  3R6V A;  4BAA A;  2NYF A;  4FFX A;  2O78 A;  1JSW A;  5F92 A;  1GK3 A;  1FUQ A;  2FUS A;  1C3C A;  4C5S A;  4EEI A;  1TJV A;  4C6G A;  2X75 A;  1XWO A;  1K7W A;  2PTQ A;  1RE5 A;  1U16 A;  3NZ4 A;  1Q5N A;  1YFM A;  3QBP A;  3GZH A;  1B8F A;  4V2R A;  1EB4 A;  5EYV A;  1GK2 A;  3KDY A;  1YIS A;  1W27 A;  4NLE A;  2OHY A;  3NO9 A;  2O7E A;  3OCF A;  1C3U A;  4HGV A;  1FUP A;  3GTD A;  3CZO A;  2QVE A;  4FLC A;  3OCE A;  3R6Y A;  1T6P A;  4NSL A;  1TJU A;  5F91 A;  2PTR A;  1HY1 A;  2NYN A;  4C5R A;  2J91 A;  3KDZ A;  4V2Q A;  2O7D A;  3RD8 A;  1Y2M A;  3BHG A;  4C5U A;  1YFE A;  1J3U A;  4APB A;  1K62 A;  1FUR A;  2QGA B;  5EYT A;  4CQ5 A;  5D6B A;  4MX2 A;  3UNV A;  2VD6 A;  1TJ7 A;  1FUO A;  3R6Q A;  1KQ7 A;  2PFM A;  1TJW A;  4ADL A;  1DCN A;  4ADM A;  1GKJ A;  2O7F A;  3RRP A;  4EFC A;  3TV2 A;  1U15 A;  2O6Y A;  4APA A;  1GKM A;  2O7B A;  1VDK A;  1HY0 A;  2RJS A;  2E9F A;  5HW2 A;  1AUW A;  3E04 A;  2RJR A;  1I0A A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...