4C5RA

Structural investigations into the stereochemistry and activity of a phenylalanine-2,3-aminomutase from taxus chinensis
Total Genus 264
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
264
sequence length
667
structure length
634
Chain Sequence
b'SHVKDILGLINAFNEVKKITVDGTTPITVAHVAALARRHDVKVALEACRARVETCSSWVQRKAEDGADIYGVTTGFGACSSRRTNRLSELQESLIRCLLAGVFTELPATATRSAMLLRLNSFTYGCSGIRWEVMEALEKLLNSNVSPKVPLRGSVSDLIPLAYIAGLLIGKPSVIARIGDDVEVPAPEALSRVGLRPFKLQAKEGLALVNGTSFATAVASTVMYDANVLLLLVETLCGMFCEVIFGREEFAHPLIHKVKPHPGQIESAELLEWLLRSSPFQELSREYYSIDKLKKPKQDRYALRSSPQWLAPLVQTIRDATTTVETEVNSANDNPIIDHANDRALHGANFQGSAVGFYMDYVRIAVAGLGKLLFAQFTELMIEYYSNGLPGNLSLGPDLSVDYGLKGLDIAMAAYSSELQYLANPVTTHVHSAEQHNQDINSLALISARKTEEALDILKLMIASHLTAMCQAVDLRQLEEALVKVVENVVSTLADECGLPNDTKARLLYVAKAVPVYTYLESPCDPTLPLLLGLKQSCFDTILALTLVDRLAEFEKRLSDRLENEMTAVRVLYEVRIQGSKFLPFYRFVREELDTGVMSARREQTPQEDVQKVFDAIADGRITVPLLHCLQGFL'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords PHENYLALANINE AMMONIA-LYASE
molecule tags Lyase
source organism Taxus wallichiana var. chinensis
publication title Structural Investigations Into the Stereochemistry and Activity of a Phenylalanine-2,3-Aminomutase from Taxus Chinensis.
pubmed doi rcsb
total genus 264
structure length 634
sequence length 667
chains with identical sequence B, C, D
ec nomenclature ec 4.3.1.24: Phenylalanine ammonia-lyase.
pdb deposition date 2013-09-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.20 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 Phenylalanine ammonia-lyase 1; domain 3 4c5rA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 4c5rA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 4c5rA02
1FURA 1HY0A 1U15A 2O7BA 3QBPA 4V2QA 1J3UA 2QVEA 2HVGA 1C3UA 1AUWA 3R6QA 1KQ7A 4C6GA 2PTSA 1I0AA 1HY1A 1XWOA 2O7DA 3R6YA 1DCNA 5D6BA 3C8TA 5F91A 2E9FA 3R6VA 2RJRA 2YIIA 1VDKA 3BHGA 2VD6A 4CQ5A 1GK3A 1RE5A 2FUSA 1YISA 1K62A 3NZ4A 4FLCA 2X75A 1Y2MA 2RJSA 3E04A 1T6JA 1TJUA 3KDYA 5HW2A 4V2RA 5EYVA 1JSWA 3UNVA 4C5SA 3RRPA 4APAA 4HGVA 1TJ7A 1U16A 3GZHA 2O6YA 1GK2A 3TV2A 4BAAA 2NYNA 1YFMA 2PTQA 2O7FA 1GKJA 4BABA 3NO9A 1B8FA 4MX2A 3GTDA 4C5UA 4FFXA 4APBA 4C5RA 1W27A 2NYFA 5F92A 1T6PA 3CZOA 1GKMA 2OHYA 4ADMA 2PFMA 2QGAB 5EYTA 4NLEA 4EEIA 2O7EA 2J91A 4ADLA 2O78A 3OCFA 3RD8A 1FUOA 1Q5NA 1TJWA 3KDZA 1TJVA 2PTRA 4EFCA 3OCEA 1FUQA 1FUPA 4NSLA 1C3CA 1EB4A 1K7WA 1YFEA 1DOFA
chains in the Genus database with same CATH superfamily
2LTHA 2A69D 3GTJA 2A6HD 2X0OA 2FENA 3CQZA 3LR6A 1EZBA 2K3OA 1FURA 1HY0A 3H0GA 1Y1WA 1U15A 1HQMD 1I50A 1TWFA 2X0PA 1XMCA 2O7BA 3QBPA 2VL7A 4V2QA 2EZAA 1J3UA 2QVEA 2HVGA 1C3UA 4CEIA 1AUWA 3R6QA 1XLYA 2VK9A 2E2IA 3GTPA 1KQ7A 3GTLA 2LPJA 4C6GA 1I0AA 2PTSA 1HY1A 1XWOA 3GTKA 3CRVA 2O7DA 3R6YA 1YNJD 2Y0NA 1DCNA 2CW0D 3C8TA 5D6BA 5F91A 2B63A 4WNLA 2JA6A 3EZAA 1R9TA 5H8WA 2E9FA 3R6VA 2RJRA 2EZCA 2YIIA 1VDKA 3BHGA 2F5JA 1TWAA 2VD6A 2MQAA 1SFOA 4CQ5A 1GK3A 2VSFA 2R7ZA 1RE5A 2NVYA 2FUSA 1YISA 3FKIA 1K62A 3NZ4A 4FLCA 1K83A 2X75A 1Y2MA 2YU9A 2VUMA 1WCMA 2RJSA 4CEJA 3E04A 1T6JA 2X0QA 3LR8A 1TJUA 3KDYA 2MX9A 3LRDA 2E2HA 5HW2A 2FELA 4V2RA 5EYVA 2BE5D 2R92A 1JSWA 3UNVA 4C5SA 3RRPA 4APAA 2N1DB 3GTOA 1TJ7A 4HGVA 1U16A 3GZHA 2O6YA 2EZBA 2AQLA 1GK2A 3TV2A 4BAAA 2MP0A 2NYNA 2MX8A 2R93A 1YFMA 3U44A 2PTQA 2O7FA 1TWHA 1GKJA 1TWGA 2LYIA 4BABA 1TWCA 3EZEA 3NO9A 2K3NA 1B8FA 5M0IA 4MX2A 2JA7A 4C5UA 4CEHA 1IW7D 1ZYRD 3GTDA 4FFXA 4APBA 1Y1VA 1SMYD 1I6VD 4FBSA 2HWGA 4C5RA 1W27A 2NYFA 3GTQA 3LR2A 5F92A 1T6PA 1YNND 3GTMA 3CZOA 1GKMA 2OHYA 4ADMA 2PFMA 2QGAB 1XL8A 4C2MA 4NLEA 2FIOA 5EYTA 4EEIA 2K3QA 2O7EA 2J91A 4ADLA 1I3QA 2LPIA 2O78A 4QIWA 1XL7A 3OCFA 3RD8A 1FUOA 1Q5NA 1TJWA 2O5JD 1EZAA 1XMDA 4A15A 2LKMB 3GTGA 3KDZA 1TJVA 2PTRA 4EFCA 3OCEA 3CRW1 1FUQA 1FUPA 2A6ED 3EZBA 5IZ2A 4NSLA 2NVXA 1C3CA 5M0JA 1EB4A 1K7WA 2HROA 1ZYMA 2JA5A 2N3EA 2FIPA 2A68D 3U4QA 1YFEA 1DOFA
chains in the Genus database with same CATH topology
1FURA 1HY0A 1U15A 2O7BA 3QBPA 4V2QA 1J3UA 2QVEA 2HVGA 1C3UA 1AUWA 3R6QA 1KQ7A 4C6GA 2PTSA 1I0AA 1HY1A 1XWOA 2O7DA 3R6YA 1DCNA 5D6BA 3C8TA 5F91A 2E9FA 3R6VA 2RJRA 2YIIA 1VDKA 3BHGA 2VD6A 4CQ5A 1GK3A 1RE5A 2FUSA 1YISA 1K62A 3NZ4A 4FLCA 2X75A 1Y2MA 2RJSA 3E04A 1T6JA 1TJUA 3KDYA 5HW2A 4V2RA 5EYVA 1JSWA 3UNVA 4C5SA 3RRPA 4APAA 4HGVA 1TJ7A 1U16A 3GZHA 2O6YA 1GK2A 3TV2A 4BAAA 2NYNA 1YFMA 2PTQA 2O7FA 1GKJA 4BABA 3NO9A 1B8FA 4MX2A 3GTDA 4C5UA 4FFXA 4APBA 4C5RA 1W27A 2NYFA 5F92A 1T6PA 3CZOA 1GKMA 2OHYA 4ADMA 2PFMA 2QGAB 5EYTA 4NLEA 4EEIA 2O7EA 2J91A 4ADLA 2O78A 3OCFA 3RD8A 1FUOA 1Q5NA 1TJWA 3KDZA 1TJVA 2PTRA 4EFCA 3OCEA 1FUQA 1FUPA 4NSLA 1C3CA 1EB4A 1K7WA 1YFEA 1DOFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FUR A;  1HY0 A;  1U15 A;  2O7B A;  3QBP A;  4V2Q A;  1J3U A;  2QVE A;  2HVG A;  1C3U A;  1AUW A;  3R6Q A;  1KQ7 A;  4C6G A;  2PTS A;  1I0A A;  1HY1 A;  1XWO A;  2O7D A;  3R6Y A;  1DCN A;  5D6B A;  3C8T A;  5F91 A;  2E9F A;  3R6V A;  2RJR A;  2YII A;  1VDK A;  3BHG A;  2VD6 A;  4CQ5 A;  1GK3 A;  1RE5 A;  2FUS A;  1YIS A;  1K62 A;  3NZ4 A;  4FLC A;  2X75 A;  1Y2M A;  2RJS A;  3E04 A;  1T6J A;  1TJU A;  3KDY A;  5HW2 A;  4V2R A;  5EYV A;  1JSW A;  3UNV A;  4C5S A;  3RRP A;  4APA A;  4HGV A;  1TJ7 A;  1U16 A;  3GZH A;  2O6Y A;  1GK2 A;  3TV2 A;  4BAA A;  2NYN A;  1YFM A;  2PTQ A;  2O7F A;  1GKJ A;  4BAB A;  3NO9 A;  1B8F A;  4MX2 A;  3GTD A;  4C5U A;  4FFX A;  4APB A;  4C5R A;  1W27 A;  2NYF A;  5F92 A;  1T6P A;  3CZO A;  1GKM A;  2OHY A;  4ADM A;  2PFM A;  2QGA B;  5EYT A;  4NLE A;  4EEI A;  2O7E A;  2J91 A;  4ADL A;  2O78 A;  3OCF A;  3RD8 A;  1FUO A;  1Q5N A;  1TJW A;  3KDZ A;  1TJV A;  2PTR A;  4EFC A;  3OCE A;  1FUQ A;  1FUP A;  4NSL A;  1C3C A;  1EB4 A;  1K7W A;  1YFE A;  1DOF A; 
#chains in the Genus database with same CATH topology
 2LTH A;  2A69 D;  3GTJ A;  2A6H D;  2X0O A;  2FEN A;  3CQZ A;  3LR6 A;  1EZB A;  2K3O A;  1FUR A;  1HY0 A;  3H0G A;  1Y1W A;  1U15 A;  1HQM D;  1I50 A;  1TWF A;  2X0P A;  1XMC A;  2O7B A;  3QBP A;  2VL7 A;  4V2Q A;  2EZA A;  1J3U A;  2QVE A;  2HVG A;  1C3U A;  4CEI A;  1AUW A;  3R6Q A;  1XLY A;  2VK9 A;  2E2I A;  3GTP A;  1KQ7 A;  3GTL A;  2LPJ A;  4C6G A;  1I0A A;  2PTS A;  1HY1 A;  1XWO A;  3GTK A;  3CRV A;  2O7D A;  3R6Y A;  1YNJ D;  2Y0N A;  1DCN A;  2CW0 D;  3C8T A;  5D6B A;  5F91 A;  2B63 A;  4WNL A;  2JA6 A;  3EZA A;  1R9T A;  5H8W A;  2E9F A;  3R6V A;  2RJR A;  2EZC A;  2YII A;  1VDK A;  3BHG A;  2F5J A;  1TWA A;  2VD6 A;  2MQA A;  1SFO A;  4CQ5 A;  1GK3 A;  2VSF A;  2R7Z A;  1RE5 A;  2NVY A;  2FUS A;  1YIS A;  3FKI A;  1K62 A;  3NZ4 A;  4FLC A;  1K83 A;  2X75 A;  1Y2M A;  2YU9 A;  2VUM A;  1WCM A;  2RJS A;  4CEJ A;  3E04 A;  1T6J A;  2X0Q A;  3LR8 A;  1TJU A;  3KDY A;  2MX9 A;  3LRD A;  2E2H A;  5HW2 A;  2FEL A;  4V2R A;  5EYV A;  2BE5 D;  2R92 A;  1JSW A;  3UNV A;  4C5S A;  3RRP A;  4APA A;  2N1D B;  3GTO A;  1TJ7 A;  4HGV A;  1U16 A;  3GZH A;  2O6Y A;  2EZB A;  2AQL A;  1GK2 A;  3TV2 A;  4BAA A;  2MP0 A;  2NYN A;  2MX8 A;  2R93 A;  1YFM A;  3U44 A;  2PTQ A;  2O7F A;  1TWH A;  1GKJ A;  1TWG A;  2LYI A;  4BAB A;  1TWC A;  3EZE A;  3NO9 A;  2K3N A;  1B8F A;  5M0I A;  4MX2 A;  2JA7 A;  4C5U A;  4CEH A;  1IW7 D;  1ZYR D;  3GTD A;  4FFX A;  4APB A;  1Y1V A;  1SMY D;  1I6V D;  4FBS A;  2HWG A;  4C5R A;  1W27 A;  2NYF A;  3GTQ A;  3LR2 A;  5F92 A;  1T6P A;  1YNN D;  3GTM A;  3CZO A;  1GKM A;  2OHY A;  4ADM A;  2PFM A;  2QGA B;  1XL8 A;  4C2M A;  4NLE A;  2FIO A;  5EYT A;  4EEI A;  2K3Q A;  2O7E A;  2J91 A;  4ADL A;  1I3Q A;  2LPI A;  2O78 A;  4QIW A;  1XL7 A;  3OCF A;  3RD8 A;  1FUO A;  1Q5N A;  1TJW A;  2O5J D;  1EZA A;  1XMD A;  4A15 A;  2LKM B;  3GTG A;  3KDZ A;  1TJV A;  2PTR A;  4EFC A;  3OCE A;  3CRW 1;  1FUQ A;  1FUP A;  2A6E D;  3EZB A;  5IZ2 A;  4NSL A;  2NVX A;  1C3C A;  5M0J A;  1EB4 A;  1K7W A;  2HRO A;  1ZYM A;  2JA5 A;  2N3E A;  2FIP A;  2A68 D;  3U4Q A;  1YFE A;  1DOF A; 
#chains in the Genus database with same CATH homology
 1FUR A;  1HY0 A;  1U15 A;  2O7B A;  3QBP A;  4V2Q A;  1J3U A;  2QVE A;  2HVG A;  1C3U A;  1AUW A;  3R6Q A;  1KQ7 A;  4C6G A;  2PTS A;  1I0A A;  1HY1 A;  1XWO A;  2O7D A;  3R6Y A;  1DCN A;  5D6B A;  3C8T A;  5F91 A;  2E9F A;  3R6V A;  2RJR A;  2YII A;  1VDK A;  3BHG A;  2VD6 A;  4CQ5 A;  1GK3 A;  1RE5 A;  2FUS A;  1YIS A;  1K62 A;  3NZ4 A;  4FLC A;  2X75 A;  1Y2M A;  2RJS A;  3E04 A;  1T6J A;  1TJU A;  3KDY A;  5HW2 A;  4V2R A;  5EYV A;  1JSW A;  3UNV A;  4C5S A;  3RRP A;  4APA A;  4HGV A;  1TJ7 A;  1U16 A;  3GZH A;  2O6Y A;  1GK2 A;  3TV2 A;  4BAA A;  2NYN A;  1YFM A;  2PTQ A;  2O7F A;  1GKJ A;  4BAB A;  3NO9 A;  1B8F A;  4MX2 A;  3GTD A;  4C5U A;  4FFX A;  4APB A;  4C5R A;  1W27 A;  2NYF A;  5F92 A;  1T6P A;  3CZO A;  1GKM A;  2OHY A;  4ADM A;  2PFM A;  2QGA B;  5EYT A;  4NLE A;  4EEI A;  2O7E A;  2J91 A;  4ADL A;  2O78 A;  3OCF A;  3RD8 A;  1FUO A;  1Q5N A;  1TJW A;  3KDZ A;  1TJV A;  2PTR A;  4EFC A;  3OCE A;  1FUQ A;  1FUP A;  4NSL A;  1C3C A;  1EB4 A;  1K7W A;  1YFE A;  1DOF A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...