3EZAA

Complex of the amino terminal domain of enzyme i and the histidine-containing phosphocarrier protein hpr from escherichia coli nmr, restrained regularized mean structure
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
249
structure length
249
Chain Sequence
MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRAVQEQVASE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the 40,000 Mr phosphoryl transfer complex between the N-terminal domain of enzyme I and HPr.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Complex (transferase/phosphocarrier)
molecule keywords PHOSPHOTRANSFERASE SYSTEM, ENZYME I
total genus 69
structure length 249
sequence length 249
ec nomenclature ec 2.7.3.9: Phosphoenolpyruvate--protein phosphotransferase.
pdb deposition date 1998-11-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00391 PEP-utilizers PEP-utilising enzyme, mobile domain
A PF05524 PEP-utilisers_N PEP-utilising enzyme, N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.10 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 PtsI, HPr-binding domain 3ezaA02
3.50.30.10 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Phosphohistidine domain 3ezaA01
1KBLA 2MP0A 1GGOA 1JDEA 3EZEA 3T0TA 2EZAA 3T07A 2EZBA 3EZAA 2E28A 2R82A 2HROA 3T05A 1EZAA 5JVLA 2FM4A 1ZYMA 2OLSA 2X0SA 1EZBA 2HWGA 2HI6A 1DIKA 3EZBA 1VBHA 1VBGA 2DIKA 2EZCA 1KC7A
chains in the Genus database with same CATH superfamily
2JA6A 1YNND 2C6PA 3FEEA 1TWHA 2PCNA 2VK9A 4TJXA 3EZEA 2D0OA 3GTKA 4MCPA 3C8OA 4C8CA 4C99A 5FD8A 2VUMA 4QIWA 1NXJA 1Z8LA 3TLEA 4C9VA 2E2IA 5F09A 1IW7D 3BI1A 3CQZA 2EZBA 1V6CA 3G23A 5F1YA 3EIFA 3S9NA 3U44A 1Q5XA 1ZYMA 2C5QA 3LR2A 2XEJA 3GJZA 3SR3A 3SJXA 2JA5A 1I3QA 3TLZA 3KRVA 4NGMA 3NOJA 3GTQA 4MCQA 4OC4A 3GTJA 3TLCA 2LYIA 2NVXA 4EYSA 3KASA 2OOTA 3SJGA 4CEHA 2R93A 1DIKA 2AUMA 1HQMD 2CIJA 2HI6A 2YJVA 3TYXA 3EZBA 4C8TA 1CS0B 2DIKA 4C2MA 1WCMA 4P4FA 5JYBA 4BABA 1Y1VA 4C84A 4P45A 1T6PA 3GTPA 4C8FA 4IIYA 2GP4A 2N3EA 4P4IA 4CEIA 2PVVA 4JYWA 2O5JD 1JDEA 2K3NA 1GGOA 2EK9A 2LKMB 2YJTA 3LR8A 3FEDA 3I74A 3K4IA 4CQ5A 4V2QA 4C5UA 2N1DB 4J0NA 4NGPA 3SJFA 2K3OA 1BXRB 4COGA 1TWFA 2A6ED 1NBWA 1C30B 2FIOA 4KNGE 3EZAA 2R82A 4C6GA 2JBJA 4NGTA 5JVLA 1R9TA 2E2HA 4TJVA 5F5XA 3S9LA 2F5JA 2LPJA 3H0GA 4INJA 2XEIA 2OLSA 3TLGB 4C9UA 1I6VD 4M8DA 3BI0A 3TLBA 4CEJA 3IIBA 2HWGA 1KEEB 1VI4A 2YIIA 3ICUA 1JDBC 2C6CA 4IIXA 5ELYA 4C86A 1TWGA 3D7FA 2XEGA 1Y9ZA 2JA7A 4C5RA 4P4BA 3D7GA 4NGQA 1TWCA 3GTOA 2D0PA 4CDJA 2FIPA 3FF3A 1CX8A 2JBKA 2C6GA 1KBLA 4P44A 3I6SA 4H1HA 2K3QA 4C85A 4OMEA 3T0TA 1ZRSA 3K9TA 2X0PA 1CE8B 2X0OA 1TWAA 1C3OB 1A9XB 4OC3A 2NVYA 4MJXA 4JZ0A 4C8PA 2E28A 1I50A 3GTGA 3T05A 1Y1WA 2LPIA 3FKIA 5IZ2A 4CZ1A 2FM4A 2R7ZA 1WVMA 1ZYRD 2PVWA 1T6JA 3D7HA 4P4JA 3TLGA 1XF1A 3S9MA 4NGNA 5F9MA 4CO9A 2B63A 4W9YA 4X3RA 5D29A 4C5SA 3GTMA 1YNJD 2X0QA 2B0AA 2R92A 4C9AA 2CW0D 1SMYD 4C8AA 4LQGA 4E5SA 4OC0A 1VBGA 1ZL0A 2EZCA 1SFOA 4P4EA 1KC7A 3T5MA 2AQLA 4MCRA 3TLAA 4CDKA 2YU9A 1M6VB 3NZ4A 2MQAA 1R61A 2OR4A 4COBA 2XEFA 5IR2A 3FECA 2MP0A 3GTLA 2Y0NA 3RBUA 4TWEA 4OC1A 4OC5A 3U4QA 4C9RA 1K83A 4C8UA 4BAAA 4E94A 5IB9A 2EZAA 2A68D 4YN3A 3BHXA 3T07A 4MI1A 4V2RA 3IWWA 2HROA 1EZAA 2MX8A 4NGSA 4P4DA 1Y2MA 2MX9A 2AUNA 3LR6A 3LRDA 1DE4C 2X0SA 3D7DA 1T36B 3TLYA 4OC2A 1EZBA 3U1BA 2EK8A 3VTAA 4MCSA 4JVOA 5K99A 2BE5D 4NGRA 1W27A 2A69D 1J3LA 1VBHA 3BXMA 4FBSA 2LTHA 3SJEA 2A6HD 4C9EA
chains in the Genus database with same CATH topology
1KBLA 2MP0A 1GGOA 1JDEA 3EZEA 3T0TA 2EZAA 3T07A 2EZBA 3EZAA 2E28A 2R82A 2HROA 3T05A 1EZAA 5JVLA 2FM4A 1ZYMA 2OLSA 2X0SA 1EZBA 2HWGA 2HI6A 1DIKA 3EZBA 1VBHA 1VBGA 2DIKA 2EZCA 1KC7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KBL A;  2MP0 A;  1GGO A;  1JDE A;  3EZE A;  3T0T A;  2EZA A;  3T07 A;  2EZB A;  3EZA A;  2E28 A;  2R82 A;  2HRO A;  3T05 A;  1EZA A;  5JVL A;  2FM4 A;  1ZYM A;  2OLS A;  2X0S A;  1EZB A;  2HWG A;  2HI6 A;  1DIK A;  3EZB A;  1VBH A;  1VBG A;  2DIK A;  2EZC A;  1KC7 A; 
#chains in the Genus database with same CATH topology
 2JA6 A;  1YNN D;  2C6P A;  3FEE A;  1TWH A;  2PCN A;  2VK9 A;  4TJX A;  3EZE A;  2D0O A;  3GTK A;  4MCP A;  3C8O A;  4C8C A;  4C99 A;  5FD8 A;  2VUM A;  4QIW A;  1NXJ A;  1Z8L A;  3TLE A;  4C9V A;  2E2I A;  5F09 A;  1IW7 D;  3BI1 A;  3CQZ A;  2EZB A;  1V6C A;  3G23 A;  5F1Y A;  3EIF A;  3S9N A;  3U44 A;  1Q5X A;  1ZYM A;  2C5Q A;  3LR2 A;  2XEJ A;  3GJZ A;  3SR3 A;  3SJX A;  2JA5 A;  1I3Q A;  3TLZ A;  3KRV A;  4NGM A;  3NOJ A;  3GTQ A;  4MCQ A;  4OC4 A;  3GTJ A;  3TLC A;  2LYI A;  2NVX A;  4EYS A;  3KAS A;  2OOT A;  3SJG A;  4CEH A;  2R93 A;  1DIK A;  2AUM A;  1HQM D;  2CIJ A;  2HI6 A;  2YJV A;  3TYX A;  3EZB A;  4C8T A;  1CS0 B;  2DIK A;  4C2M A;  1WCM A;  4P4F A;  5JYB A;  4BAB A;  1Y1V A;  4C84 A;  4P45 A;  1T6P A;  3GTP A;  4C8F A;  4IIY A;  2GP4 A;  2N3E A;  4P4I A;  4CEI A;  2PVV A;  4JYW A;  2O5J D;  1JDE A;  2K3N A;  1GGO A;  2EK9 A;  2LKM B;  2YJT A;  3LR8 A;  3FED A;  3I74 A;  3K4I A;  4CQ5 A;  4V2Q A;  4C5U A;  2N1D B;  4J0N A;  4NGP A;  3SJF A;  2K3O A;  1BXR B;  4COG A;  1TWF A;  2A6E D;  1NBW A;  1C30 B;  2FIO A;  4KNG E;  3EZA A;  2R82 A;  4C6G A;  2JBJ A;  4NGT A;  5JVL A;  1R9T A;  2E2H A;  4TJV A;  5F5X A;  3S9L A;  2F5J A;  2LPJ A;  3H0G A;  4INJ A;  2XEI A;  2OLS A;  3TLG B;  4C9U A;  1I6V D;  4M8D A;  3BI0 A;  3TLB A;  4CEJ A;  3IIB A;  2HWG A;  1KEE B;  1VI4 A;  2YII A;  3ICU A;  1JDB C;  2C6C A;  4IIX A;  5ELY A;  4C86 A;  1TWG A;  3D7F A;  2XEG A;  1Y9Z A;  2JA7 A;  4C5R A;  4P4B A;  3D7G A;  4NGQ A;  1TWC A;  3GTO A;  2D0P A;  4CDJ A;  2FIP A;  3FF3 A;  1CX8 A;  2JBK A;  2C6G A;  1KBL A;  4P44 A;  3I6S A;  4H1H A;  2K3Q A;  4C85 A;  4OME A;  3T0T A;  1ZRS A;  3K9T A;  2X0P A;  1CE8 B;  2X0O A;  1TWA A;  1C3O B;  1A9X B;  4OC3 A;  2NVY A;  4MJX A;  4JZ0 A;  4C8P A;  2E28 A;  1I50 A;  3GTG A;  3T05 A;  1Y1W A;  2LPI A;  3FKI A;  5IZ2 A;  4CZ1 A;  2FM4 A;  2R7Z A;  1WVM A;  1ZYR D;  2PVW A;  1T6J A;  3D7H A;  4P4J A;  3TLG A;  1XF1 A;  3S9M A;  4NGN A;  5F9M A;  4CO9 A;  2B63 A;  4W9Y A;  4X3R A;  5D29 A;  4C5S A;  3GTM A;  1YNJ D;  2X0Q A;  2B0A A;  2R92 A;  4C9A A;  2CW0 D;  1SMY D;  4C8A A;  4LQG A;  4E5S A;  4OC0 A;  1VBG A;  1ZL0 A;  2EZC A;  1SFO A;  4P4E A;  1KC7 A;  3T5M A;  2AQL A;  4MCR A;  3TLA A;  4CDK A;  2YU9 A;  1M6V B;  3NZ4 A;  2MQA A;  1R61 A;  2OR4 A;  4COB A;  2XEF A;  5IR2 A;  3FEC A;  2MP0 A;  3GTL A;  2Y0N A;  3RBU A;  4TWE A;  4OC1 A;  4OC5 A;  3U4Q A;  4C9R A;  1K83 A;  4C8U A;  4BAA A;  4E94 A;  5IB9 A;  2EZA A;  2A68 D;  4YN3 A;  3BHX A;  3T07 A;  4MI1 A;  4V2R A;  3IWW A;  2HRO A;  1EZA A;  2MX8 A;  4NGS A;  4P4D A;  1Y2M A;  2MX9 A;  2AUN A;  3LR6 A;  3LRD A;  1DE4 C;  2X0S A;  3D7D A;  1T36 B;  3TLY A;  4OC2 A;  1EZB A;  3U1B A;  2EK8 A;  3VTA A;  4MCS A;  4JVO A;  5K99 A;  2BE5 D;  4NGR A;  1W27 A;  2A69 D;  1J3L A;  1VBH A;  3BXM A;  4FBS A;  2LTH A;  3SJE A;  2A6H D;  4C9E A; 
#chains in the Genus database with same CATH homology
 1KBL A;  2MP0 A;  1GGO A;  1JDE A;  3EZE A;  3T0T A;  2EZA A;  3T07 A;  2EZB A;  3EZA A;  2E28 A;  2R82 A;  2HRO A;  3T05 A;  1EZA A;  5JVL A;  2FM4 A;  1ZYM A;  2OLS A;  2X0S A;  1EZB A;  2HWG A;  2HI6 A;  1DIK A;  3EZB A;  1VBH A;  1VBG A;  2DIK A;  2EZC A;  1KC7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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