3EZAA

Complex of the amino terminal domain of enzyme i and the histidine-containing phosphocarrier protein hpr from escherichia coli nmr, restrained regularized mean structure
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
249
structure length
249
Chain Sequence
MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRAVQEQVASE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Complex (transferase/phosphocarrier)
molecule keywords PHOSPHOTRANSFERASE SYSTEM, ENZYME I
publication title Solution structure of the 40,000 Mr phosphoryl transfer complex between the N-terminal domain of enzyme I and HPr.
pubmed doi rcsb
source organism Escherichia coli
total genus 69
structure length 249
sequence length 249
ec nomenclature ec 2.7.3.9: Phosphoenolpyruvate--protein phosphotransferase.
pdb deposition date 1998-11-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00391 PEP-utilizers PEP-utilising enzyme, mobile domain
A PF05524 PEP-utilisers_N PEP-utilising enzyme, N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.10 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 PtsI, HPr-binding domain 3ezaA02
3.50.30.10 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Phosphohistidine domain 3ezaA01
3EZAA 2EZBA 2MP0A 1KC7A 3EZBA 2E28A 1ZYMA 1DIKA 3EZEA 2R82A 3T07A 5JVLA 2HROA 1VBGA 2EZCA 2X0SA 1VBHA 1EZBA 2HWGA 2HI6A 1EZAA 1GGOA 2DIKA 1JDEA 1KBLA 2FM4A 3T0TA 3T05A 2OLSA 2EZAA
chains in the Genus database with same CATH superfamily
2A6ED 3SR3A 3SJFA 4V2RA 1CE8B 2HROA 2A68D 4MI1A 1NBWA 2F5JA 1I3QA 3KASA 4TWEA 1T36B 2LYIA 2C6GA 1HQMD 4COGA 4OC0A 3I74A 1WCMA 2EZAA 1R61A 4C8CA 5K99A 2MP0A 2MQAA 3U1BA 1TWAA 1V6CA 3TLYA 3EIFA 2K3NA 3TLZA 1A9XB 5IZ2A 1WVMA 3TYXA 4COBA 2E2IA 2N3EA 3RBUA 4C8FA 2OLSA 1C3OB 4MCSA 1CS0B 2VK9A 3EZBA 4P4FA 3BHXA 3D7DA 3EZEA 2EK9A 4C5UA 4C8UA 4C5SA 2R92A 4MJXA 1XF1A 4C9AA 2X0QA 2YJVA 3GTKA 4CQ5A 4CEJA 3LR6A 2O5JD 4OC4A 5IR2A 3SJXA 3GTQA 1CX8A 4OMEA 4C6GA 2D0OA 4JYWA 4EYSA 4INJA 4M8DA 4J0NA 2X0OA 3FECA 3S9NA 2A69D 2JA5A 4C9EA 1TWFA 4C99A 3T5MA 3TLGA 4BABA 3T05A 4CDJA 5FD8A 3GTLA 2FIOA 2NVXA 2K3OA 4P4EA 2NVYA 2YU9A 2EZCA 3ICUA 1I50A 1EZAA 1KBLA 2JA6A 4FBSA 4QIWA 1Y1WA 2K3QA 2LPJA 4JZ0A 3T07A 5F1YA 3S9LA 5F9MA 1VBGA 2R93A 3U4QA 4H1HA 1R9TA 2XEGA 4CDKA 4IIXA 3T0TA 4NGTA 2XEIA 1TWCA 2XEJA 4YN3A 1Y1VA 3D7HA 1W27A 4MCPA 1JDBC 1VBHA 2DIKA 3H0GA 3NOJA 2FM4A 2AUMA 3TLBA 4P44A 4C5RA 1YNND 2Y0NA 2JA7A 2LTHA 2R82A 3TLAA 5JVLA 4CO9A 3GTGA 3K4IA 2OR4A 4C2MA 1EZBA 5F09A 4V2QA 4LQGA 3FF3A 3IWWA 3GTOA 4NGRA 1K83A 1ZRSA 2EZBA 3G23A 3GTJA 2AUNA 2PVWA 1J3LA 3U44A 2C6PA 1I6VD 4NGNA 4C8TA 3GTMA 1Q5XA 1GGOA 1VI4A 1T6JA 1JDEA 3VTAA 3D7GA 4E5SA 4C8AA 3EZAA 3CQZA 1TWGA 2XEFA 4X3RA 2E28A 1T6PA 2CW0D 4MCQA 3K9TA 1Y9ZA 4P45A 2X0SA 1SMYD 4NGMA 3BXMA 4TJVA 4BAAA 2HI6A 1Y2MA 3FEDA 4C84A 2MX9A 4C85A 2YJTA 2D0PA 3SJGA 1DE4C 2CIJA 4NGQA 1C30B 4IIYA 4C9VA 2FIPA 1ZYRD 2B63A 2HWGA 4C86A 5F5XA 3GTPA 3C8OA 2JBJA 5JYBA 3SJEA 5D29A 2JBKA 3TLGB 4JVOA 1BXRB 3GJZA 4OC2A 2VUMA 2C5QA 2YIIA 3D7FA 1IW7D 2N1DB 3LR2A 4TJXA 2BE5D 1KEEB 5ELYA 1KC7A 4C9RA 3BI1A 3TLEA 2AQLA 4C8PA 3FEEA 2R7ZA 4CEHA 3FKIA 4OC3A 5IB9A 1M6VB 1SFOA 1YNJD 3BI0A 4CEIA 3KRVA 4NGSA 2LKMB 2PVVA 1NXJA 4NGPA 4P4DA 1ZYMA 1DIKA 4W9YA 2MX8A 3IIBA 2LPIA 1ZL0A 4C9UA 2E2HA 2X0PA 3I6SA 4P4JA 2C6CA 3NZ4A 3TLCA 4P4BA 4P4IA 2GP4A 3LR8A 3LRDA 2OOTA 4OC1A 1Z8LA 4E94A 3S9MA 2EK8A 2A6HD 4KNGE 4OC5A 2B0AA 1TWHA 4CZ1A 4MCRA 2PCNA
chains in the Genus database with same CATH topology
3EZAA 2EZBA 2MP0A 1KC7A 3EZBA 2E28A 1ZYMA 1DIKA 3EZEA 2R82A 3T07A 5JVLA 2HROA 1VBGA 2EZCA 2X0SA 1VBHA 1EZBA 2HWGA 2HI6A 1EZAA 1GGOA 2DIKA 1JDEA 1KBLA 2FM4A 3T0TA 3T05A 2OLSA 2EZAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EZA A;  2EZB A;  2MP0 A;  1KC7 A;  3EZB A;  2E28 A;  1ZYM A;  1DIK A;  3EZE A;  2R82 A;  3T07 A;  5JVL A;  2HRO A;  1VBG A;  2EZC A;  2X0S A;  1VBH A;  1EZB A;  2HWG A;  2HI6 A;  1EZA A;  1GGO A;  2DIK A;  1JDE A;  1KBL A;  2FM4 A;  3T0T A;  3T05 A;  2OLS A;  2EZA A; 
#chains in the Genus database with same CATH topology
 2A6E D;  3SR3 A;  3SJF A;  4V2R A;  1CE8 B;  2HRO A;  2A68 D;  4MI1 A;  1NBW A;  2F5J A;  1I3Q A;  3KAS A;  4TWE A;  1T36 B;  2LYI A;  2C6G A;  1HQM D;  4COG A;  4OC0 A;  3I74 A;  1WCM A;  2EZA A;  1R61 A;  4C8C A;  5K99 A;  2MP0 A;  2MQA A;  3U1B A;  1TWA A;  1V6C A;  3TLY A;  3EIF A;  2K3N A;  3TLZ A;  1A9X B;  5IZ2 A;  1WVM A;  3TYX A;  4COB A;  2E2I A;  2N3E A;  3RBU A;  4C8F A;  2OLS A;  1C3O B;  4MCS A;  1CS0 B;  2VK9 A;  3EZB A;  4P4F A;  3BHX A;  3D7D A;  3EZE A;  2EK9 A;  4C5U A;  4C8U A;  4C5S A;  2R92 A;  4MJX A;  1XF1 A;  4C9A A;  2X0Q A;  2YJV A;  3GTK A;  4CQ5 A;  4CEJ A;  3LR6 A;  2O5J D;  4OC4 A;  5IR2 A;  3SJX A;  3GTQ A;  1CX8 A;  4OME A;  4C6G A;  2D0O A;  4JYW A;  4EYS A;  4INJ A;  4M8D A;  4J0N A;  2X0O A;  3FEC A;  3S9N A;  2A69 D;  2JA5 A;  4C9E A;  1TWF A;  4C99 A;  3T5M A;  3TLG A;  4BAB A;  3T05 A;  4CDJ A;  5FD8 A;  3GTL A;  2FIO A;  2NVX A;  2K3O A;  4P4E A;  2NVY A;  2YU9 A;  2EZC A;  3ICU A;  1I50 A;  1EZA A;  1KBL A;  2JA6 A;  4FBS A;  4QIW A;  1Y1W A;  2K3Q A;  2LPJ A;  4JZ0 A;  3T07 A;  5F1Y A;  3S9L A;  5F9M A;  1VBG A;  2R93 A;  3U4Q A;  4H1H A;  1R9T A;  2XEG A;  4CDK A;  4IIX A;  3T0T A;  4NGT A;  2XEI A;  1TWC A;  2XEJ A;  4YN3 A;  1Y1V A;  3D7H A;  1W27 A;  4MCP A;  1JDB C;  1VBH A;  2DIK A;  3H0G A;  3NOJ A;  2FM4 A;  2AUM A;  3TLB A;  4P44 A;  4C5R A;  1YNN D;  2Y0N A;  2JA7 A;  2LTH A;  2R82 A;  3TLA A;  5JVL A;  4CO9 A;  3GTG A;  3K4I A;  2OR4 A;  4C2M A;  1EZB A;  5F09 A;  4V2Q A;  4LQG A;  3FF3 A;  3IWW A;  3GTO A;  4NGR A;  1K83 A;  1ZRS A;  2EZB A;  3G23 A;  3GTJ A;  2AUN A;  2PVW A;  1J3L A;  3U44 A;  2C6P A;  1I6V D;  4NGN A;  4C8T A;  3GTM A;  1Q5X A;  1GGO A;  1VI4 A;  1T6J A;  1JDE A;  3VTA A;  3D7G A;  4E5S A;  4C8A A;  3EZA A;  3CQZ A;  1TWG A;  2XEF A;  4X3R A;  2E28 A;  1T6P A;  2CW0 D;  4MCQ A;  3K9T A;  1Y9Z A;  4P45 A;  2X0S A;  1SMY D;  4NGM A;  3BXM A;  4TJV A;  4BAA A;  2HI6 A;  1Y2M A;  3FED A;  4C84 A;  2MX9 A;  4C85 A;  2YJT A;  2D0P A;  3SJG A;  1DE4 C;  2CIJ A;  4NGQ A;  1C30 B;  4IIY A;  4C9V A;  2FIP A;  1ZYR D;  2B63 A;  2HWG A;  4C86 A;  5F5X A;  3GTP A;  3C8O A;  2JBJ A;  5JYB A;  3SJE A;  5D29 A;  2JBK A;  3TLG B;  4JVO A;  1BXR B;  3GJZ A;  4OC2 A;  2VUM A;  2C5Q A;  2YII A;  3D7F A;  1IW7 D;  2N1D B;  3LR2 A;  4TJX A;  2BE5 D;  1KEE B;  5ELY A;  1KC7 A;  4C9R A;  3BI1 A;  3TLE A;  2AQL A;  4C8P A;  3FEE A;  2R7Z A;  4CEH A;  3FKI A;  4OC3 A;  5IB9 A;  1M6V B;  1SFO A;  1YNJ D;  3BI0 A;  4CEI A;  3KRV A;  4NGS A;  2LKM B;  2PVV A;  1NXJ A;  4NGP A;  4P4D A;  1ZYM A;  1DIK A;  4W9Y A;  2MX8 A;  3IIB A;  2LPI A;  1ZL0 A;  4C9U A;  2E2H A;  2X0P A;  3I6S A;  4P4J A;  2C6C A;  3NZ4 A;  3TLC A;  4P4B A;  4P4I A;  2GP4 A;  3LR8 A;  3LRD A;  2OOT A;  4OC1 A;  1Z8L A;  4E94 A;  3S9M A;  2EK8 A;  2A6H D;  4KNG E;  4OC5 A;  2B0A A;  1TWH A;  4CZ1 A;  4MCR A;  2PCN A; 
#chains in the Genus database with same CATH homology
 3EZA A;  2EZB A;  2MP0 A;  1KC7 A;  3EZB A;  2E28 A;  1ZYM A;  1DIK A;  3EZE A;  2R82 A;  3T07 A;  5JVL A;  2HRO A;  1VBG A;  2EZC A;  2X0S A;  1VBH A;  1EZB A;  2HWG A;  2HI6 A;  1EZA A;  1GGO A;  2DIK A;  1JDE A;  1KBL A;  2FM4 A;  3T0T A;  3T05 A;  2OLS A;  2EZA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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