3EZAA

Complex of the amino terminal domain of enzyme i and the histidine-containing phosphocarrier protein hpr from escherichia coli nmr, restrained regularized mean structure
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
249
structure length
249
Chain Sequence
MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRAVQEQVASE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords PHOSPHOTRANSFERASE SYSTEM, ENZYME I
publication title Solution structure of the 40,000 Mr phosphoryl transfer complex between the N-terminal domain of enzyme I and HPr.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Complex (transferase/phosphocarrier)
total genus 69
structure length 249
sequence length 249
ec nomenclature ec 2.7.3.9: Phosphoenolpyruvate--protein phosphotransferase.
pdb deposition date 1998-11-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00391 PEP-utilizers PEP-utilising enzyme, mobile domain
A PF05524 PEP-utilisers_N PEP-utilising enzyme, N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.10 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 PtsI, HPr-binding domain 3ezaA02
3.50.30.10 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Phosphohistidine domain 3ezaA01
2HI6A 5JVLA 3T05A 1GGOA 2OLSA 1JDEA 1EZBA 2HROA 1VBGA 2X0SA 3T0TA 3EZBA 1KC7A 3T07A 2EZAA 2FM4A 1EZAA 1VBHA 3EZEA 2E28A 3EZAA 2MP0A 2R82A 1KBLA 2DIKA 1ZYMA 2EZBA 2HWGA 1DIKA 2EZCA
chains in the Genus database with same CATH superfamily
4OC1A 3LR2A 2CIJA 3TLAA 2LYIA 2A69D 4CDKA 1JDBC 4J0NA 4COGA 4C8PA 4C5RA 2EK8A 2X0OA 1XF1A 4X3RA 4TWEA 2JA5A 2K3OA 1WCMA 2E2IA 1ZYRD 3BI1A 1W27A 4MCRA 2NVXA 2N3EA 4C6GA 1SMYD 3BXMA 1T36B 1K83A 1BXRB 2X0SA 5FD8A 1YNND 2X0PA 4C84A 4C9AA 1V6CA 3FKIA 1NBWA 1NXJA 2B0AA 2N1DB 4P4FA 3GTGA 1HQMD 4C8TA 2K3NA 3G23A 3TLGB 1Y9ZA 2LPJA 1VBGA 3EZBA 1VBHA 2NVYA 4IIXA 1T6JA 5IR2A 3LR8A 2O5JD 1R61A 3FEEA 3S9MA 3EIFA 2VUMA 3BHXA 4CZ1A 1CE8B 2EZAA 2JBJA 4C9EA 4NGMA 4P4IA 2JA7A 2PVVA 1C3OB 5F1YA 3H0GA 2JA6A 2HWGA 3NZ4A 4H1HA 3GTKA 2EZCA 1J3LA 4NGNA 2HI6A 4NGSA 1TWHA 4QIWA 2C6GA 3U1BA 2FM4A 3LR6A 2R93A 4P4BA 4C9UA 1IW7D 2FIPA 4CEJA 5F5XA 4C9VA 2GP4A 4C8AA 3D7DA 4MCQA 1I50A 4OC0A 5ELYA 1TWCA 4MCPA 2C6CA 3C8OA 3T0TA 3FEDA 4LQGA 4YN3A 3SJEA 3T07A 3KRVA 2C6PA 4INJA 2A6ED 3FF3A 2PVWA 4JYWA 2OR4A 5IZ2A 2MX9A 5D29A 2AUNA 3T5MA 2HROA 4C5SA 3GJZA 5F9MA 1Q5XA 4W9YA 2PCNA 3S9NA 3GTOA 2R82A 3CQZA 2R7ZA 1I6VD 4C8CA 3D7HA 4MI1A 2CW0D 2MX8A 3SR3A 3TYXA 2LTHA 4C5UA 4OMEA 4C8UA 1WVMA 4TJXA 4NGRA 3EZEA 3BI0A 2A6HD 4C99A 3U44A 4MJXA 4P4EA 1TWGA 2B63A 4FBSA 5K99A 2YU9A 3I74A 1I3QA 2AUMA 4COBA 2YJTA 2LPIA 4CQ5A 1SFOA 4E5SA 5IB9A 4OC2A 2EK9A 2C5QA 2X0QA 3D7FA 4OC4A 1DE4C 4KNGE 4OC3A 2XEJA 1EZAA 3TLYA 2YIIA 4CEIA 4NGTA 2E2HA 4CDJA 2AQLA 3GTPA 1DIKA 3K9TA 3TLZA 1EZBA 1M6VB 3IIBA 2XEFA 3D7GA 1ZRSA 4MCSA 2A68D 4BAAA 4P45A 4P44A 4JZ0A 3TLEA 4E94A 3GTLA 1ZL0A 1KEEB 3KASA 4CO9A 1VI4A 1JDEA 4C85A 2LKMB 4P4DA 3IWWA 4JVOA 4C86A 4NGQA 3SJXA 2JBKA 3SJGA 4IIYA 2YJVA 5F09A 3K4IA 2VK9A 3TLCA 4C8FA 4TJVA 2R92A 4EYSA 1CS0B 2OOTA 3LRDA 1YNJD 1Y2MA 1GGOA 2K3QA 3TLGA 3RBUA 4CEHA 1A9XB 3GTMA 2E28A 2MP0A 4OC5A 2MQAA 2EZBA 4NGPA 3NOJA 2BE5D 5JVLA 3T05A 3ICUA 4C9RA 3VTAA 1T6PA 4V2QA 2Y0NA 1R9TA 1Y1VA 2F5JA 2D0OA 4M8DA 3S9LA 3I6SA 4P4JA 4C2MA 3FECA 1CX8A 2XEIA 1Y1WA 1ZYMA 3U4QA 1Z8LA 2OLSA 1TWFA 2XEGA 4BABA 2FIOA 3GTJA 1KC7A 3SJFA 5JYBA 3GTQA 3EZAA 2D0PA 1KBLA 3TLBA 2DIKA 1TWAA 4V2RA 1C30B
chains in the Genus database with same CATH topology
2HI6A 5JVLA 3T05A 1GGOA 2OLSA 1JDEA 1EZBA 2HROA 1VBGA 2X0SA 3T0TA 3EZBA 1KC7A 3T07A 2EZAA 2FM4A 1EZAA 1VBHA 3EZEA 2E28A 3EZAA 2MP0A 2R82A 1KBLA 2DIKA 1ZYMA 2EZBA 2HWGA 1DIKA 2EZCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HI6 A;  5JVL A;  3T05 A;  1GGO A;  2OLS A;  1JDE A;  1EZB A;  2HRO A;  1VBG A;  2X0S A;  3T0T A;  3EZB A;  1KC7 A;  3T07 A;  2EZA A;  2FM4 A;  1EZA A;  1VBH A;  3EZE A;  2E28 A;  3EZA A;  2MP0 A;  2R82 A;  1KBL A;  2DIK A;  1ZYM A;  2EZB A;  2HWG A;  1DIK A;  2EZC A; 
#chains in the Genus database with same CATH topology
 4OC1 A;  3LR2 A;  2CIJ A;  3TLA A;  2LYI A;  2A69 D;  4CDK A;  1JDB C;  4J0N A;  4COG A;  4C8P A;  4C5R A;  2EK8 A;  2X0O A;  1XF1 A;  4X3R A;  4TWE A;  2JA5 A;  2K3O A;  1WCM A;  2E2I A;  1ZYR D;  3BI1 A;  1W27 A;  4MCR A;  2NVX A;  2N3E A;  4C6G A;  1SMY D;  3BXM A;  1T36 B;  1K83 A;  1BXR B;  2X0S A;  5FD8 A;  1YNN D;  2X0P A;  4C84 A;  4C9A A;  1V6C A;  3FKI A;  1NBW A;  1NXJ A;  2B0A A;  2N1D B;  4P4F A;  3GTG A;  1HQM D;  4C8T A;  2K3N A;  3G23 A;  3TLG B;  1Y9Z A;  2LPJ A;  1VBG A;  3EZB A;  1VBH A;  2NVY A;  4IIX A;  1T6J A;  5IR2 A;  3LR8 A;  2O5J D;  1R61 A;  3FEE A;  3S9M A;  3EIF A;  2VUM A;  3BHX A;  4CZ1 A;  1CE8 B;  2EZA A;  2JBJ A;  4C9E A;  4NGM A;  4P4I A;  2JA7 A;  2PVV A;  1C3O B;  5F1Y A;  3H0G A;  2JA6 A;  2HWG A;  3NZ4 A;  4H1H A;  3GTK A;  2EZC A;  1J3L A;  4NGN A;  2HI6 A;  4NGS A;  1TWH A;  4QIW A;  2C6G A;  3U1B A;  2FM4 A;  3LR6 A;  2R93 A;  4P4B A;  4C9U A;  1IW7 D;  2FIP A;  4CEJ A;  5F5X A;  4C9V A;  2GP4 A;  4C8A A;  3D7D A;  4MCQ A;  1I50 A;  4OC0 A;  5ELY A;  1TWC A;  4MCP A;  2C6C A;  3C8O A;  3T0T A;  3FED A;  4LQG A;  4YN3 A;  3SJE A;  3T07 A;  3KRV A;  2C6P A;  4INJ A;  2A6E D;  3FF3 A;  2PVW A;  4JYW A;  2OR4 A;  5IZ2 A;  2MX9 A;  5D29 A;  2AUN A;  3T5M A;  2HRO A;  4C5S A;  3GJZ A;  5F9M A;  1Q5X A;  4W9Y A;  2PCN A;  3S9N A;  3GTO A;  2R82 A;  3CQZ A;  2R7Z A;  1I6V D;  4C8C A;  3D7H A;  4MI1 A;  2CW0 D;  2MX8 A;  3SR3 A;  3TYX A;  2LTH A;  4C5U A;  4OME A;  4C8U A;  1WVM A;  4TJX A;  4NGR A;  3EZE A;  3BI0 A;  2A6H D;  4C99 A;  3U44 A;  4MJX A;  4P4E A;  1TWG A;  2B63 A;  4FBS A;  5K99 A;  2YU9 A;  3I74 A;  1I3Q A;  2AUM A;  4COB A;  2YJT A;  2LPI A;  4CQ5 A;  1SFO A;  4E5S A;  5IB9 A;  4OC2 A;  2EK9 A;  2C5Q A;  2X0Q A;  3D7F A;  4OC4 A;  1DE4 C;  4KNG E;  4OC3 A;  2XEJ A;  1EZA A;  3TLY A;  2YII A;  4CEI A;  4NGT A;  2E2H A;  4CDJ A;  2AQL A;  3GTP A;  1DIK A;  3K9T A;  3TLZ A;  1EZB A;  1M6V B;  3IIB A;  2XEF A;  3D7G A;  1ZRS A;  4MCS A;  2A68 D;  4BAA A;  4P45 A;  4P44 A;  4JZ0 A;  3TLE A;  4E94 A;  3GTL A;  1ZL0 A;  1KEE B;  3KAS A;  4CO9 A;  1VI4 A;  1JDE A;  4C85 A;  2LKM B;  4P4D A;  3IWW A;  4JVO A;  4C86 A;  4NGQ A;  3SJX A;  2JBK A;  3SJG A;  4IIY A;  2YJV A;  5F09 A;  3K4I A;  2VK9 A;  3TLC A;  4C8F A;  4TJV A;  2R92 A;  4EYS A;  1CS0 B;  2OOT A;  3LRD A;  1YNJ D;  1Y2M A;  1GGO A;  2K3Q A;  3TLG A;  3RBU A;  4CEH A;  1A9X B;  3GTM A;  2E28 A;  2MP0 A;  4OC5 A;  2MQA A;  2EZB A;  4NGP A;  3NOJ A;  2BE5 D;  5JVL A;  3T05 A;  3ICU A;  4C9R A;  3VTA A;  1T6P A;  4V2Q A;  2Y0N A;  1R9T A;  1Y1V A;  2F5J A;  2D0O A;  4M8D A;  3S9L A;  3I6S A;  4P4J A;  4C2M A;  3FEC A;  1CX8 A;  2XEI A;  1Y1W A;  1ZYM A;  3U4Q A;  1Z8L A;  2OLS A;  1TWF A;  2XEG A;  4BAB A;  2FIO A;  3GTJ A;  1KC7 A;  3SJF A;  5JYB A;  3GTQ A;  3EZA A;  2D0P A;  1KBL A;  3TLB A;  2DIK A;  1TWA A;  4V2R A;  1C30 B; 
#chains in the Genus database with same CATH homology
 2HI6 A;  5JVL A;  3T05 A;  1GGO A;  2OLS A;  1JDE A;  1EZB A;  2HRO A;  1VBG A;  2X0S A;  3T0T A;  3EZB A;  1KC7 A;  3T07 A;  2EZA A;  2FM4 A;  1EZA A;  1VBH A;  3EZE A;  2E28 A;  3EZA A;  2MP0 A;  2R82 A;  1KBL A;  2DIK A;  1ZYM A;  2EZB A;  2HWG A;  1DIK A;  2EZC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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