1W27A

Phenylalanine ammonia-lyase (pal) from petroselinum crispum
Total Genus 254
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
254
sequence length
690
structure length
689
Chain Sequence
EDPLYWGIAAEAMTGSHLDEVKKMVAEYRKPVVKLGGETLTISQVAAISARDGSGVTVELSEAARAGVKASSDWVMDSMNKGTDSYGVTTGFGATSHRRTKQGGALQKELIRFLNAGIFGNGSDNTLPHSATRAAMLVRINTLLQGYSGIRFEILEAITKFLNQNITPCLPLRGTITDLVPLSYIAGLLTGRPNSKAVGPTGVILSPEEAFKLAGVEGGFFELQPKEGLALVNGTAVGSGMASMVLFEANILAVLAEVMSAIFAEVMQGKPEFTDHLTHKLKHHPGQIEAAAIMEHILDGSAYVKAAQKLHEMDPLQKPKQDRYALRTSPQWLGPQIEVIRSSTKMIEREINSVNDNPLIDVSRNKAIHGGNFQGTPIGVSMDNTRLAIAAIGKLMFAQFSELVNDFYNNGLPSNLSGGRNPSLDYGFKGAEIAMASYCSELQFLANPVTNHVQSAEQHNQDVNSLGLISSRKTSEAVEILKLMSTTFLVGLCQAIDLRHLEENLKSTVKNTVSSVAKRVLTMGVNGELHPSRFCEKDLLRVVDREYIFAYIDDPCSATYPLMQKLRQTLVEHALKNGDNERNLSTSIFQKIATFEDELKALLPKEVESARAALESGNPAIPNRIEECRSYPLYKFVRKELGTEYLTGEKVTSPGEEFEKVFIAMSKGEIIDPLLECLESWNGAPLPIC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords PHENYLALANINE AMMONIA-LYASE 1
publication title Structural Basis for the Entrance Into the Phenylpropanoid Metabolism Catalyzed by Phenylalanine Ammonia-Lyase
pubmed doi rcsb
source organism Petroselinum crispum
molecule tags Lyase
total genus 254
structure length 689
sequence length 690
chains with identical sequence B
ec nomenclature ec 4.3.1.24: Phenylalanine ammonia-lyase.
pdb deposition date 2004-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.20 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 Phenylalanine ammonia-lyase 1; domain 3 1w27A03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1w27A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1w27A02
1YFMA 1TJVA 1GK3A 1K62A 1U16A 1TJWA 1YFEA 5EYVA 1B8FA 1I0AA 3OCFA 1T6PA 4BABA 1HY0A 2RJSA 2OHYA 2O7EA 2PFMA 2QGAB 4NLEA 2NYFA 5HW2A 1FUOA 1EB4A 2NYNA 1DCNA 4ADMA 3NZ4A 2PTQA 3TV2A 4EFCA 1T6JA 3GTDA 1K7WA 4HGVA 5F91A 1J3UA 2RJRA 3RRPA 1Q5NA 3CZOA 1HY1A 2J91A 4NSLA 1U15A 4FLCA 3R6YA 4CQ5A 4C5RA 1GK2A 1YISA 2QVEA 2YIIA 4MX2A 2O7BA 2O78A 1TJUA 3BHGA 2O7DA 1GKJA 4C5SA 3E04A 4V2RA 1C3UA 2HVGA 3OCEA 4BAAA 2E9FA 5EYTA 1GKMA 1FURA 2O6YA 1Y2MA 1VDKA 4V2QA 4APBA 1DOFA 1FUPA 3R6VA 4C5UA 4C6GA 1AUWA 1TJ7A 3QBPA 3R6QA 3GZHA 3UNVA 2X75A 4EEIA 4APAA 1W27A 3KDYA 5F92A 3NO9A 1KQ7A 1JSWA 2PTSA 4ADLA 1RE5A 1C3CA 3C8TA 2VD6A 3KDZA 1FUQA 5D6BA 2O7FA 1XWOA 2FUSA 4FFXA 3RD8A 2PTRA
chains in the Genus database with same CATH superfamily
1YFMA 1EZAA 1TWGA 3CQZA 2VK9A 1HQMD 1GK3A 1K62A 2LPJA 1TJVA 2EZBA 1TJWA 2HROA 3GTQA 1U16A 1YFEA 2E2IA 4WNLA 2A6ED 5EYVA 2VSFA 1TWCA 1XL8A 1B8FA 5IZ2A 1I0AA 3EZEA 3OCFA 1T6PA 4BABA 2NVYA 1HY0A 3GTKA 2RJSA 4C2MA 2B63A 2OHYA 2O7EA 2PFMA 2QGAB 2LYIA 4NLEA 2NYFA 2E2HA 3LRDA 2FENA 5HW2A 1FUOA 1EB4A 2CW0D 1I50A 2NVXA 2NYNA 1DCNA 4ADMA 3LR8A 3NZ4A 4CEJA 2PTQA 3TV2A 4EFCA 1T6JA 3GTDA 1ZYRD 2HWGA 2X0PA 1K7WA 2K3NA 1YNND 1Y1WA 4HGVA 3LR6A 3GTJA 1J3UA 5F91A 2RJRA 3RRPA 2Y0NA 1Q5NA 1TWFA 1EZBA 3CZOA 1HY1A 2J91A 3H0GA 2BE5D 2F5JA 1XL7A 4NSLA 2X0QA 1U15A 2JA7A 4FLCA 3R6YA 2R93A 4CQ5A 4C5RA 1YNJD 1GK2A 1YISA 1SMYD 2QVEA 2MQAA 2YIIA 2O7BA 4MX2A 2MP0A 5M0JA 2O78A 1TJUA 2VUMA 3BHGA 1WCMA 2O7DA 1GKJA 4A15A 4CEHA 4C5SA 3CRVA 3E04A 2A68D 1SFOA 4V2RA 3GTPA 2JA5A 1C3UA 2E9FA 2HVGA 2A6HD 4BAAA 3OCEA 5EYTA 1GKMA 1FURA 2O6YA 1IW7D 1XLYA 1Y2MA 1I6VD 2JA6A 1Y1VA 1VDKA 4V2QA 4APBA 1DOFA 1FUPA 3R6VA 2AQLA 4C5UA 2O5JD 2X0OA 4C6GA 4CEIA 3GTLA 2FIOA 3U44A 3CRW1 1AUWA 2K3OA 1TJ7A 1TWHA 2MX8A 3QBPA 4QIWA 3R6QA 2R92A 3GZHA 3UNVA 3GTMA 5M0IA 2X75A 2EZAA 4EEIA 4APAA 1W27A 1XMDA 2LKMB 2LPIA 3KDYA 1ZYMA 2N1DB 1R9TA 2K3QA 2LTHA 5F92A 3NO9A 3GTOA 1KQ7A 1JSWA 2N3EA 2PTSA 4ADLA 1RE5A 2A69D 3FKIA 5H8WA 2MX9A 4FBSA 1C3CA 3C8TA 2VD6A 2YU9A 2FIPA 3KDZA 1FUQA 5D6BA 2O7FA 2VL7A 3U4QA 2FELA 1XWOA 1XMCA 1TWAA 3GTGA 2FUSA 2R7ZA 3LR2A 1I3QA 3EZBA 2EZCA 4FFXA 3EZAA 3RD8A 1K83A 2PTRA
chains in the Genus database with same CATH topology
1YFMA 1TJVA 1GK3A 1K62A 1U16A 1TJWA 1YFEA 5EYVA 1B8FA 1I0AA 3OCFA 1T6PA 4BABA 1HY0A 2RJSA 2OHYA 2O7EA 2PFMA 2QGAB 4NLEA 2NYFA 5HW2A 1FUOA 1EB4A 2NYNA 1DCNA 4ADMA 3NZ4A 2PTQA 3TV2A 4EFCA 1T6JA 3GTDA 1K7WA 4HGVA 5F91A 1J3UA 2RJRA 3RRPA 1Q5NA 3CZOA 1HY1A 2J91A 4NSLA 1U15A 4FLCA 3R6YA 4CQ5A 4C5RA 1GK2A 1YISA 2QVEA 2YIIA 4MX2A 2O7BA 2O78A 1TJUA 3BHGA 2O7DA 1GKJA 4C5SA 3E04A 4V2RA 1C3UA 2HVGA 3OCEA 4BAAA 2E9FA 5EYTA 1GKMA 1FURA 2O6YA 1Y2MA 1VDKA 4V2QA 4APBA 1DOFA 1FUPA 3R6VA 4C5UA 4C6GA 1AUWA 1TJ7A 3QBPA 3R6QA 3GZHA 3UNVA 2X75A 4EEIA 4APAA 1W27A 3KDYA 5F92A 3NO9A 1KQ7A 1JSWA 2PTSA 4ADLA 1RE5A 1C3CA 3C8TA 2VD6A 3KDZA 1FUQA 5D6BA 2O7FA 1XWOA 2FUSA 4FFXA 3RD8A 2PTRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YFM A;  1TJV A;  1GK3 A;  1K62 A;  1U16 A;  1TJW A;  1YFE A;  5EYV A;  1B8F A;  1I0A A;  3OCF A;  1T6P A;  4BAB A;  1HY0 A;  2RJS A;  2OHY A;  2O7E A;  2PFM A;  2QGA B;  4NLE A;  2NYF A;  5HW2 A;  1FUO A;  1EB4 A;  2NYN A;  1DCN A;  4ADM A;  3NZ4 A;  2PTQ A;  3TV2 A;  4EFC A;  1T6J A;  3GTD A;  1K7W A;  4HGV A;  5F91 A;  1J3U A;  2RJR A;  3RRP A;  1Q5N A;  3CZO A;  1HY1 A;  2J91 A;  4NSL A;  1U15 A;  4FLC A;  3R6Y A;  4CQ5 A;  4C5R A;  1GK2 A;  1YIS A;  2QVE A;  2YII A;  4MX2 A;  2O7B A;  2O78 A;  1TJU A;  3BHG A;  2O7D A;  1GKJ A;  4C5S A;  3E04 A;  4V2R A;  1C3U A;  2HVG A;  3OCE A;  4BAA A;  2E9F A;  5EYT A;  1GKM A;  1FUR A;  2O6Y A;  1Y2M A;  1VDK A;  4V2Q A;  4APB A;  1DOF A;  1FUP A;  3R6V A;  4C5U A;  4C6G A;  1AUW A;  1TJ7 A;  3QBP A;  3R6Q A;  3GZH A;  3UNV A;  2X75 A;  4EEI A;  4APA A;  1W27 A;  3KDY A;  5F92 A;  3NO9 A;  1KQ7 A;  1JSW A;  2PTS A;  4ADL A;  1RE5 A;  1C3C A;  3C8T A;  2VD6 A;  3KDZ A;  1FUQ A;  5D6B A;  2O7F A;  1XWO A;  2FUS A;  4FFX A;  3RD8 A;  2PTR A; 
#chains in the Genus database with same CATH topology
 1YFM A;  1EZA A;  1TWG A;  3CQZ A;  2VK9 A;  1HQM D;  1GK3 A;  1K62 A;  2LPJ A;  1TJV A;  2EZB A;  1TJW A;  2HRO A;  3GTQ A;  1U16 A;  1YFE A;  2E2I A;  4WNL A;  2A6E D;  5EYV A;  2VSF A;  1TWC A;  1XL8 A;  1B8F A;  5IZ2 A;  1I0A A;  3EZE A;  3OCF A;  1T6P A;  4BAB A;  2NVY A;  1HY0 A;  3GTK A;  2RJS A;  4C2M A;  2B63 A;  2OHY A;  2O7E A;  2PFM A;  2QGA B;  2LYI A;  4NLE A;  2NYF A;  2E2H A;  3LRD A;  2FEN A;  5HW2 A;  1FUO A;  1EB4 A;  2CW0 D;  1I50 A;  2NVX A;  2NYN A;  1DCN A;  4ADM A;  3LR8 A;  3NZ4 A;  4CEJ A;  2PTQ A;  3TV2 A;  4EFC A;  1T6J A;  3GTD A;  1ZYR D;  2HWG A;  2X0P A;  1K7W A;  2K3N A;  1YNN D;  1Y1W A;  4HGV A;  3LR6 A;  3GTJ A;  1J3U A;  5F91 A;  2RJR A;  3RRP A;  2Y0N A;  1Q5N A;  1TWF A;  1EZB A;  3CZO A;  1HY1 A;  2J91 A;  3H0G A;  2BE5 D;  2F5J A;  1XL7 A;  4NSL A;  2X0Q A;  1U15 A;  2JA7 A;  4FLC A;  3R6Y A;  2R93 A;  4CQ5 A;  4C5R A;  1YNJ D;  1GK2 A;  1YIS A;  1SMY D;  2QVE A;  2MQA A;  2YII A;  2O7B A;  4MX2 A;  2MP0 A;  5M0J A;  2O78 A;  1TJU A;  2VUM A;  3BHG A;  1WCM A;  2O7D A;  1GKJ A;  4A15 A;  4CEH A;  4C5S A;  3CRV A;  3E04 A;  2A68 D;  1SFO A;  4V2R A;  3GTP A;  2JA5 A;  1C3U A;  2E9F A;  2HVG A;  2A6H D;  4BAA A;  3OCE A;  5EYT A;  1GKM A;  1FUR A;  2O6Y A;  1IW7 D;  1XLY A;  1Y2M A;  1I6V D;  2JA6 A;  1Y1V A;  1VDK A;  4V2Q A;  4APB A;  1DOF A;  1FUP A;  3R6V A;  2AQL A;  4C5U A;  2O5J D;  2X0O A;  4C6G A;  4CEI A;  3GTL A;  2FIO A;  3U44 A;  3CRW 1;  1AUW A;  2K3O A;  1TJ7 A;  1TWH A;  2MX8 A;  3QBP A;  4QIW A;  3R6Q A;  2R92 A;  3GZH A;  3UNV A;  3GTM A;  5M0I A;  2X75 A;  2EZA A;  4EEI A;  4APA A;  1W27 A;  1XMD A;  2LKM B;  2LPI A;  3KDY A;  1ZYM A;  2N1D B;  1R9T A;  2K3Q A;  2LTH A;  5F92 A;  3NO9 A;  3GTO A;  1KQ7 A;  1JSW A;  2N3E A;  2PTS A;  4ADL A;  1RE5 A;  2A69 D;  3FKI A;  5H8W A;  2MX9 A;  4FBS A;  1C3C A;  3C8T A;  2VD6 A;  2YU9 A;  2FIP A;  3KDZ A;  1FUQ A;  5D6B A;  2O7F A;  2VL7 A;  3U4Q A;  2FEL A;  1XWO A;  1XMC A;  1TWA A;  3GTG A;  2FUS A;  2R7Z A;  3LR2 A;  1I3Q A;  3EZB A;  2EZC A;  4FFX A;  3EZA A;  3RD8 A;  1K83 A;  2PTR A; 
#chains in the Genus database with same CATH homology
 1YFM A;  1TJV A;  1GK3 A;  1K62 A;  1U16 A;  1TJW A;  1YFE A;  5EYV A;  1B8F A;  1I0A A;  3OCF A;  1T6P A;  4BAB A;  1HY0 A;  2RJS A;  2OHY A;  2O7E A;  2PFM A;  2QGA B;  4NLE A;  2NYF A;  5HW2 A;  1FUO A;  1EB4 A;  2NYN A;  1DCN A;  4ADM A;  3NZ4 A;  2PTQ A;  3TV2 A;  4EFC A;  1T6J A;  3GTD A;  1K7W A;  4HGV A;  5F91 A;  1J3U A;  2RJR A;  3RRP A;  1Q5N A;  3CZO A;  1HY1 A;  2J91 A;  4NSL A;  1U15 A;  4FLC A;  3R6Y A;  4CQ5 A;  4C5R A;  1GK2 A;  1YIS A;  2QVE A;  2YII A;  4MX2 A;  2O7B A;  2O78 A;  1TJU A;  3BHG A;  2O7D A;  1GKJ A;  4C5S A;  3E04 A;  4V2R A;  1C3U A;  2HVG A;  3OCE A;  4BAA A;  2E9F A;  5EYT A;  1GKM A;  1FUR A;  2O6Y A;  1Y2M A;  1VDK A;  4V2Q A;  4APB A;  1DOF A;  1FUP A;  3R6V A;  4C5U A;  4C6G A;  1AUW A;  1TJ7 A;  3QBP A;  3R6Q A;  3GZH A;  3UNV A;  2X75 A;  4EEI A;  4APA A;  1W27 A;  3KDY A;  5F92 A;  3NO9 A;  1KQ7 A;  1JSW A;  2PTS A;  4ADL A;  1RE5 A;  1C3C A;  3C8T A;  2VD6 A;  3KDZ A;  1FUQ A;  5D6B A;  2O7F A;  1XWO A;  2FUS A;  4FFX A;  3RD8 A;  2PTR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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