1W27A

Phenylalanine ammonia-lyase (pal) from petroselinum crispum
Total Genus 254
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
254
sequence length
690
structure length
689
Chain Sequence
EDPLYWGIAAEAMTGSHLDEVKKMVAEYRKPVVKLGGETLTISQVAAISARDGSGVTVELSEAARAGVKASSDWVMDSMNKGTDSYGVTTGFGATSHRRTKQGGALQKELIRFLNAGIFGNGSDNTLPHSATRAAMLVRINTLLQGYSGIRFEILEAITKFLNQNITPCLPLRGTITDLVPLSYIAGLLTGRPNSKAVGPTGVILSPEEAFKLAGVEGGFFELQPKEGLALVNGTAVGSGMASMVLFEANILAVLAEVMSAIFAEVMQGKPEFTDHLTHKLKHHPGQIEAAAIMEHILDGSAYVKAAQKLHEMDPLQKPKQDRYALRTSPQWLGPQIEVIRSSTKMIEREINSVNDNPLIDVSRNKAIHGGNFQGTPIGVSMDNTRLAIAAIGKLMFAQFSELVNDFYNNGLPSNLSGGRNPSLDYGFKGAEIAMASYCSELQFLANPVTNHVQSAEQHNQDVNSLGLISSRKTSEAVEILKLMSTTFLVGLCQAIDLRHLEENLKSTVKNTVSSVAKRVLTMGVNGELHPSRFCEKDLLRVVDREYIFAYIDDPCSATYPLMQKLRQTLVEHALKNGDNERNLSTSIFQKIATFEDELKALLPKEVESARAALESGNPAIPNRIEECRSYPLYKFVRKELGTEYLTGEKVTSPGEEFEKVFIAMSKGEIIDPLLECLESWNGAPLPIC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Lyase
molecule keywords PHENYLALANINE AMMONIA-LYASE 1
publication title Structural Basis for the Entrance Into the Phenylpropanoid Metabolism Catalyzed by Phenylalanine Ammonia-Lyase
pubmed doi rcsb
source organism Petroselinum crispum
total genus 254
structure length 689
sequence length 690
chains with identical sequence B
ec nomenclature ec 4.3.1.24: Phenylalanine ammonia-lyase.
pdb deposition date 2004-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.20 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 Phenylalanine ammonia-lyase 1; domain 3 1w27A03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1w27A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1w27A02
4C5UA 1B8FA 1Y2MA 4FLCA 2X75A 4MX2A 2PTSA 4ADLA 4BAAA 4C6GA 4V2RA 1FUPA 3R6QA 4EFCA 1YFMA 2NYFA 3E04A 2PTRA 1W27A 2OHYA 1HY0A 1RE5A 2VD6A 3OCFA 3BHGA 4HGVA 3CZOA 2PFMA 3UNVA 2PTQA 1YFEA 3KDZA 1T6JA 2O7DA 3NZ4A 3TV2A 3GTDA 2O6YA 2O7FA 5D6BA 1T6PA 2J91A 1XWOA 3C8TA 2O7EA 4CQ5A 1I0AA 1C3CA 2HVGA 2RJRA 3KDYA 1DOFA 1TJ7A 2FUSA 5EYVA 2O7BA 1FURA 3OCEA 5HW2A 4ADMA 4C5SA 1J3UA 4EEIA 4NSLA 4APBA 4V2QA 1KQ7A 1GK3A 4BABA 1HY1A 3R6VA 1TJUA 1GKMA 3QBPA 2NYNA 1K7WA 1EB4A 2QGAB 1K62A 1VDKA 4C5RA 1DCNA 3GZHA 1JSWA 1TJVA 5EYTA 4FFXA 1FUOA 4APAA 1FUQA 1YISA 5F91A 5F92A 1GKJA 3RD8A 3R6YA 3RRPA 1AUWA 1TJWA 2O78A 2QVEA 4NLEA 1Q5NA 3NO9A 1GK2A 2RJSA 2YIIA 1U15A 1C3UA 1U16A 2E9FA
chains in the Genus database with same CATH superfamily
4C5UA 2R93A 1B8FA 1EZAA 1Y2MA 2X0QA 1YNND 4FLCA 2E2IA 2X75A 1I6VD 4MX2A 2PTSA 4ADLA 4BAAA 4QIWA 3FKIA 4C6GA 2LYIA 2MX9A 2R7ZA 1TWFA 2CW0D 3LRDA 2VL7A 4V2RA 1FUPA 3R6QA 4EFCA 2NVXA 3CQZA 4CEIA 1YFMA 5IZ2A 2NYFA 3E04A 2PTRA 5H8WA 2JA5A 1SFOA 2X0PA 2BE5D 3LR8A 1W27A 2OHYA 1HY0A 1RE5A 1XL7A 1IW7D 4C2MA 2VD6A 3CRVA 3OCFA 3BHGA 4HGVA 3CZOA 2FELA 1TWHA 2PFMA 3UNVA 2PTQA 1YFEA 1XL8A 1SMYD 3KDZA 5M0JA 1R9TA 1T6JA 2O7DA 5M0IA 3NZ4A 3TV2A 2HROA 1XMDA 3GTDA 2O6YA 2A6HD 1Y1WA 2B63A 1I3QA 2A69D 1I50A 1T6PA 2O7FA 3CRW1 5D6BA 2A6ED 2VK9A 3GTJA 2EZCA 1XWOA 2J91A 2O7EA 3C8TA 2N3EA 2F5JA 2N1DB 1EZBA 3GTOA 2EZBA 4CQ5A 2MQAA 1I0AA 1C3CA 2HVGA 2NVYA 2RJRA 1Y1VA 1ZYRD 1DOFA 2A68D 1TJ7A 2FUSA 3KDYA 2LKMB 2O7BA 5EYVA 1FURA 3OCEA 2R92A 5HW2A 4ADMA 2JA7A 4C5SA 1J3UA 1K83A 4EEIA 2MX8A 4NSLA 4APBA 4V2QA 4A15A 1KQ7A 1GK3A 4CEJA 4BABA 1HY1A 1TWGA 1WCMA 3R6VA 1TJUA 3U44A 1GKMA 3QBPA 2NYNA 2VSFA 1K7WA 1EB4A 2K3NA 4FBSA 2QGAB 1HQMD 1K62A 4C5RA 1DCNA 1VDKA 3GZHA 2K3QA 1JSWA 1TJVA 5EYTA 3GTPA 3EZBA 2K3OA 3GTQA 1TWAA 4FFXA 2LPJA 3EZEA 3GTLA 1FUOA 4APAA 2EZAA 1FUQA 1YISA 5F91A 5F92A 1GKJA 3U4QA 3GTKA 3RD8A 3R6YA 2LPIA 3RRPA 2FIPA 2E2HA 1TWCA 2VUMA 1AUWA 2LTHA 1ZYMA 2X0OA 1TJWA 3LR2A 2YU9A 2JA6A 2Y0NA 2O78A 2QVEA 4NLEA 2MP0A 1Q5NA 1YNJD 3NO9A 1GK2A 3EZAA 2RJSA 4CEHA 2YIIA 3GTGA 2FENA 3LR6A 1U15A 2FIOA 3GTMA 3H0GA 1C3UA 1U16A 1XLYA 4WNLA 2AQLA 2E9FA 2O5JD 1XMCA 2HWGA
chains in the Genus database with same CATH topology
4C5UA 1B8FA 1Y2MA 4FLCA 2X75A 4MX2A 2PTSA 4ADLA 4BAAA 4C6GA 4V2RA 1FUPA 3R6QA 4EFCA 1YFMA 2NYFA 3E04A 2PTRA 1W27A 2OHYA 1HY0A 1RE5A 2VD6A 3OCFA 3BHGA 4HGVA 3CZOA 2PFMA 3UNVA 2PTQA 1YFEA 3KDZA 1T6JA 2O7DA 3NZ4A 3TV2A 3GTDA 2O6YA 2O7FA 5D6BA 1T6PA 2J91A 1XWOA 3C8TA 2O7EA 4CQ5A 1I0AA 1C3CA 2HVGA 2RJRA 3KDYA 1DOFA 1TJ7A 2FUSA 5EYVA 2O7BA 1FURA 3OCEA 5HW2A 4ADMA 4C5SA 1J3UA 4EEIA 4NSLA 4APBA 4V2QA 1KQ7A 1GK3A 4BABA 1HY1A 3R6VA 1TJUA 1GKMA 3QBPA 2NYNA 1K7WA 1EB4A 2QGAB 1K62A 1VDKA 4C5RA 1DCNA 3GZHA 1JSWA 1TJVA 5EYTA 4FFXA 1FUOA 4APAA 1FUQA 1YISA 5F91A 5F92A 1GKJA 3RD8A 3R6YA 3RRPA 1AUWA 1TJWA 2O78A 2QVEA 4NLEA 1Q5NA 3NO9A 1GK2A 2RJSA 2YIIA 1U15A 1C3UA 1U16A 2E9FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4C5U A;  1B8F A;  1Y2M A;  4FLC A;  2X75 A;  4MX2 A;  2PTS A;  4ADL A;  4BAA A;  4C6G A;  4V2R A;  1FUP A;  3R6Q A;  4EFC A;  1YFM A;  2NYF A;  3E04 A;  2PTR A;  1W27 A;  2OHY A;  1HY0 A;  1RE5 A;  2VD6 A;  3OCF A;  3BHG A;  4HGV A;  3CZO A;  2PFM A;  3UNV A;  2PTQ A;  1YFE A;  3KDZ A;  1T6J A;  2O7D A;  3NZ4 A;  3TV2 A;  3GTD A;  2O6Y A;  2O7F A;  5D6B A;  1T6P A;  2J91 A;  1XWO A;  3C8T A;  2O7E A;  4CQ5 A;  1I0A A;  1C3C A;  2HVG A;  2RJR A;  3KDY A;  1DOF A;  1TJ7 A;  2FUS A;  5EYV A;  2O7B A;  1FUR A;  3OCE A;  5HW2 A;  4ADM A;  4C5S A;  1J3U A;  4EEI A;  4NSL A;  4APB A;  4V2Q A;  1KQ7 A;  1GK3 A;  4BAB A;  1HY1 A;  3R6V A;  1TJU A;  1GKM A;  3QBP A;  2NYN A;  1K7W A;  1EB4 A;  2QGA B;  1K62 A;  1VDK A;  4C5R A;  1DCN A;  3GZH A;  1JSW A;  1TJV A;  5EYT A;  4FFX A;  1FUO A;  4APA A;  1FUQ A;  1YIS A;  5F91 A;  5F92 A;  1GKJ A;  3RD8 A;  3R6Y A;  3RRP A;  1AUW A;  1TJW A;  2O78 A;  2QVE A;  4NLE A;  1Q5N A;  3NO9 A;  1GK2 A;  2RJS A;  2YII A;  1U15 A;  1C3U A;  1U16 A;  2E9F A; 
#chains in the Genus database with same CATH topology
 4C5U A;  2R93 A;  1B8F A;  1EZA A;  1Y2M A;  2X0Q A;  1YNN D;  4FLC A;  2E2I A;  2X75 A;  1I6V D;  4MX2 A;  2PTS A;  4ADL A;  4BAA A;  4QIW A;  3FKI A;  4C6G A;  2LYI A;  2MX9 A;  2R7Z A;  1TWF A;  2CW0 D;  3LRD A;  2VL7 A;  4V2R A;  1FUP A;  3R6Q A;  4EFC A;  2NVX A;  3CQZ A;  4CEI A;  1YFM A;  5IZ2 A;  2NYF A;  3E04 A;  2PTR A;  5H8W A;  2JA5 A;  1SFO A;  2X0P A;  2BE5 D;  3LR8 A;  1W27 A;  2OHY A;  1HY0 A;  1RE5 A;  1XL7 A;  1IW7 D;  4C2M A;  2VD6 A;  3CRV A;  3OCF A;  3BHG A;  4HGV A;  3CZO A;  2FEL A;  1TWH A;  2PFM A;  3UNV A;  2PTQ A;  1YFE A;  1XL8 A;  1SMY D;  3KDZ A;  5M0J A;  1R9T A;  1T6J A;  2O7D A;  5M0I A;  3NZ4 A;  3TV2 A;  2HRO A;  1XMD A;  3GTD A;  2O6Y A;  2A6H D;  1Y1W A;  2B63 A;  1I3Q A;  2A69 D;  1I50 A;  1T6P A;  2O7F A;  3CRW 1;  5D6B A;  2A6E D;  2VK9 A;  3GTJ A;  2EZC A;  1XWO A;  2J91 A;  2O7E A;  3C8T A;  2N3E A;  2F5J A;  2N1D B;  1EZB A;  3GTO A;  2EZB A;  4CQ5 A;  2MQA A;  1I0A A;  1C3C A;  2HVG A;  2NVY A;  2RJR A;  1Y1V A;  1ZYR D;  1DOF A;  2A68 D;  1TJ7 A;  2FUS A;  3KDY A;  2LKM B;  2O7B A;  5EYV A;  1FUR A;  3OCE A;  2R92 A;  5HW2 A;  4ADM A;  2JA7 A;  4C5S A;  1J3U A;  1K83 A;  4EEI A;  2MX8 A;  4NSL A;  4APB A;  4V2Q A;  4A15 A;  1KQ7 A;  1GK3 A;  4CEJ A;  4BAB A;  1HY1 A;  1TWG A;  1WCM A;  3R6V A;  1TJU A;  3U44 A;  1GKM A;  3QBP A;  2NYN A;  2VSF A;  1K7W A;  1EB4 A;  2K3N A;  4FBS A;  2QGA B;  1HQM D;  1K62 A;  4C5R A;  1DCN A;  1VDK A;  3GZH A;  2K3Q A;  1JSW A;  1TJV A;  5EYT A;  3GTP A;  3EZB A;  2K3O A;  3GTQ A;  1TWA A;  4FFX A;  2LPJ A;  3EZE A;  3GTL A;  1FUO A;  4APA A;  2EZA A;  1FUQ A;  1YIS A;  5F91 A;  5F92 A;  1GKJ A;  3U4Q A;  3GTK A;  3RD8 A;  3R6Y A;  2LPI A;  3RRP A;  2FIP A;  2E2H A;  1TWC A;  2VUM A;  1AUW A;  2LTH A;  1ZYM A;  2X0O A;  1TJW A;  3LR2 A;  2YU9 A;  2JA6 A;  2Y0N A;  2O78 A;  2QVE A;  4NLE A;  2MP0 A;  1Q5N A;  1YNJ D;  3NO9 A;  1GK2 A;  3EZA A;  2RJS A;  4CEH A;  2YII A;  3GTG A;  2FEN A;  3LR6 A;  1U15 A;  2FIO A;  3GTM A;  3H0G A;  1C3U A;  1U16 A;  1XLY A;  4WNL A;  2AQL A;  2E9F A;  2O5J D;  1XMC A;  2HWG A; 
#chains in the Genus database with same CATH homology
 4C5U A;  1B8F A;  1Y2M A;  4FLC A;  2X75 A;  4MX2 A;  2PTS A;  4ADL A;  4BAA A;  4C6G A;  4V2R A;  1FUP A;  3R6Q A;  4EFC A;  1YFM A;  2NYF A;  3E04 A;  2PTR A;  1W27 A;  2OHY A;  1HY0 A;  1RE5 A;  2VD6 A;  3OCF A;  3BHG A;  4HGV A;  3CZO A;  2PFM A;  3UNV A;  2PTQ A;  1YFE A;  3KDZ A;  1T6J A;  2O7D A;  3NZ4 A;  3TV2 A;  3GTD A;  2O6Y A;  2O7F A;  5D6B A;  1T6P A;  2J91 A;  1XWO A;  3C8T A;  2O7E A;  4CQ5 A;  1I0A A;  1C3C A;  2HVG A;  2RJR A;  3KDY A;  1DOF A;  1TJ7 A;  2FUS A;  5EYV A;  2O7B A;  1FUR A;  3OCE A;  5HW2 A;  4ADM A;  4C5S A;  1J3U A;  4EEI A;  4NSL A;  4APB A;  4V2Q A;  1KQ7 A;  1GK3 A;  4BAB A;  1HY1 A;  3R6V A;  1TJU A;  1GKM A;  3QBP A;  2NYN A;  1K7W A;  1EB4 A;  2QGA B;  1K62 A;  1VDK A;  4C5R A;  1DCN A;  3GZH A;  1JSW A;  1TJV A;  5EYT A;  4FFX A;  1FUO A;  4APA A;  1FUQ A;  1YIS A;  5F91 A;  5F92 A;  1GKJ A;  3RD8 A;  3R6Y A;  3RRP A;  1AUW A;  1TJW A;  2O78 A;  2QVE A;  4NLE A;  1Q5N A;  3NO9 A;  1GK2 A;  2RJS A;  2YII A;  1U15 A;  1C3U A;  1U16 A;  2E9F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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