1W27A

Phenylalanine ammonia-lyase (pal) from petroselinum crispum
Total Genus 254
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
254
sequence length
690
structure length
689
Chain Sequence
EDPLYWGIAAEAMTGSHLDEVKKMVAEYRKPVVKLGGETLTISQVAAISARDGSGVTVELSEAARAGVKASSDWVMDSMNKGTDSYGVTTGFGATSHRRTKQGGALQKELIRFLNAGIFGNGSDNTLPHSATRAAMLVRINTLLQGYSGIRFEILEAITKFLNQNITPCLPLRGTITDLVPLSYIAGLLTGRPNSKAVGPTGVILSPEEAFKLAGVEGGFFELQPKEGLALVNGTAVGSGMASMVLFEANILAVLAEVMSAIFAEVMQGKPEFTDHLTHKLKHHPGQIEAAAIMEHILDGSAYVKAAQKLHEMDPLQKPKQDRYALRTSPQWLGPQIEVIRSSTKMIEREINSVNDNPLIDVSRNKAIHGGNFQGTPIGVSMDNTRLAIAAIGKLMFAQFSELVNDFYNNGLPSNLSGGRNPSLDYGFKGAEIAMASYCSELQFLANPVTNHVQSAEQHNQDVNSLGLISSRKTSEAVEILKLMSTTFLVGLCQAIDLRHLEENLKSTVKNTVSSVAKRVLTMGVNGELHPSRFCEKDLLRVVDREYIFAYIDDPCSATYPLMQKLRQTLVEHALKNGDNERNLSTSIFQKIATFEDELKALLPKEVESARAALESGNPAIPNRIEECRSYPLYKFVRKELGTEYLTGEKVTSPGEEFEKVFIAMSKGEIIDPLLECLESWNGAPLPIC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords PHENYLALANINE AMMONIA-LYASE 1
publication title Structural Basis for the Entrance Into the Phenylpropanoid Metabolism Catalyzed by Phenylalanine Ammonia-Lyase
pubmed doi rcsb
source organism Petroselinum crispum
molecule tags Lyase
total genus 254
structure length 689
sequence length 690
chains with identical sequence B
ec nomenclature ec 4.3.1.24: Phenylalanine ammonia-lyase.
pdb deposition date 2004-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.20 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 Phenylalanine ammonia-lyase 1; domain 3 1w27A03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1w27A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1w27A02
4CQ5A 2YIIA 2VD6A 3R6VA 4NLEA 2FUSA 1W27A 5EYVA 3CZOA 1RE5A 2RJRA 4BAAA 2O7DA 5F92A 1T6JA 4FLCA 1FUPA 4EEIA 1I0AA 1HY1A 3E04A 4BABA 1FURA 2OHYA 4APBA 1U15A 5F91A 4FFXA 3C8TA 4C5UA 5D6BA 3UNVA 1GKJA 3NO9A 1Q5NA 1TJWA 1C3UA 2O7FA 4HGVA 1VDKA 1B8FA 5HW2A 1K7WA 1DOFA 1HY0A 3GTDA 1K62A 3RRPA 3OCFA 3QBPA 1TJUA 1Y2MA 2QGAB 2O78A 2O7EA 3KDYA 4ADMA 4V2RA 1EB4A 3RD8A 1DCNA 4C5SA 1J3UA 1C3CA 1AUWA 4C6GA 2X75A 4V2QA 3KDZA 3R6YA 2NYNA 4MX2A 4ADLA 2RJSA 1YFEA 5EYTA 2O6YA 3BHGA 3OCEA 3R6QA 2NYFA 1GK3A 2J91A 4EFCA 1T6PA 1TJ7A 1XWOA 1FUQA 1JSWA 4C5RA 1GKMA 1FUOA 3GZHA 2HVGA 1KQ7A 2O7BA 2PFMA 2E9FA 1U16A 2PTQA 1YFMA 2QVEA 1TJVA 4NSLA 3TV2A 1GK2A 4APAA 1YISA 2PTSA 2PTRA 3NZ4A
chains in the Genus database with same CATH superfamily
2FIPA 2B63A 2R7ZA 2Y0NA 1WCMA 3U44A 1ZYMA 1ZYRD 4CQ5A 2YIIA 2LTHA 2VD6A 3GTJA 4CEHA 3R6VA 2N3EA 1YNND 3GTLA 2FUSA 4NLEA 1I6VD 1W27A 5EYVA 2LKMB 4A15A 3CZOA 2VK9A 1RE5A 2RJRA 2N1DB 1YNJD 2A6HD 2LPIA 2CW0D 2F5JA 4BAAA 2O7DA 5F92A 2JA7A 1T6JA 4FLCA 2LYIA 1FUPA 1Y1WA 4EEIA 2LPJA 1I0AA 1HY1A 3E04A 4WNLA 4QIWA 1XL8A 2VL7A 4BABA 1FURA 1SMYD 2JA5A 2OHYA 4APBA 4FBSA 2A6ED 2BE5D 1XLYA 1U15A 2X0QA 2MX9A 3U4QA 1TWAA 1XMDA 4FFXA 3C8TA 4C5UA 1TWHA 5D6BA 5F91A 2K3OA 2MP0A 3UNVA 1TWCA 1GKJA 3NO9A 2X0OA 1Q5NA 1Y1VA 1TJWA 1C3UA 3CRW1 2O7FA 4HGVA 1VDKA 1B8FA 2NVXA 5HW2A 3GTMA 2FIOA 4CEJA 1K7WA 3FKIA 1DOFA 1HY0A 1R9TA 3GTDA 3LR6A 4CEIA 1K62A 3RRPA 2A68D 3OCFA 1Y2MA 1TJUA 2O78A 2QGAB 3QBPA 3LR8A 1I3QA 2O7EA 3KDYA 4ADMA 4V2RA 1IW7D 1EB4A 3RD8A 1DCNA 4C5SA 1J3UA 1C3CA 2R92A 2EZAA 1AUWA 4C6GA 2X75A 2YU9A 2E2HA 5H8WA 4V2QA 3KDZA 3R6YA 1TWGA 2FELA 2NYNA 4MX2A 1HQMD 2K3QA 3LRDA 1YFEA 2RJSA 4ADLA 5EYTA 2EZCA 3GTQA 2MQAA 3GTGA 2O6YA 3BHGA 3OCEA 3CQZA 1TWFA 1EZBA 3R6QA 2VUMA 2NYFA 3GTOA 2O5JD 2E2IA 1GK3A 1XL7A 3CRVA 2J91A 4EFCA 1T6PA 1TJ7A 3H0GA 1XWOA 2A69D 1FUQA 1JSWA 2K3NA 3EZEA 4C5RA 3GTKA 1GKMA 1FUOA 3GZHA 2HVGA 5IZ2A 1KQ7A 2O7BA 4C2MA 2PFMA 1XMCA 2E9FA 3LR2A 5M0JA 2EZBA 1U16A 2R93A 2JA6A 2PTQA 1YFMA 3EZAA 3GTPA 2QVEA 2MX8A 2X0PA 1TJVA 1K83A 5M0IA 4NSLA 3TV2A 1EZAA 1SFOA 1GK2A 2HWGA 3EZBA 4APAA 2AQLA 2HROA 1I50A 1YISA 2PTSA 2NVYA 2FENA 2PTRA 3NZ4A 2VSFA
chains in the Genus database with same CATH topology
4CQ5A 2YIIA 2VD6A 3R6VA 4NLEA 2FUSA 1W27A 5EYVA 3CZOA 1RE5A 2RJRA 4BAAA 2O7DA 5F92A 1T6JA 4FLCA 1FUPA 4EEIA 1I0AA 1HY1A 3E04A 4BABA 1FURA 2OHYA 4APBA 1U15A 5F91A 4FFXA 3C8TA 4C5UA 5D6BA 3UNVA 1GKJA 3NO9A 1Q5NA 1TJWA 1C3UA 2O7FA 4HGVA 1VDKA 1B8FA 5HW2A 1K7WA 1DOFA 1HY0A 3GTDA 1K62A 3RRPA 3OCFA 3QBPA 1TJUA 1Y2MA 2QGAB 2O78A 2O7EA 3KDYA 4ADMA 4V2RA 1EB4A 3RD8A 1DCNA 4C5SA 1J3UA 1C3CA 1AUWA 4C6GA 2X75A 4V2QA 3KDZA 3R6YA 2NYNA 4MX2A 4ADLA 2RJSA 1YFEA 5EYTA 2O6YA 3BHGA 3OCEA 3R6QA 2NYFA 1GK3A 2J91A 4EFCA 1T6PA 1TJ7A 1XWOA 1FUQA 1JSWA 4C5RA 1GKMA 1FUOA 3GZHA 2HVGA 1KQ7A 2O7BA 2PFMA 2E9FA 1U16A 2PTQA 1YFMA 2QVEA 1TJVA 4NSLA 3TV2A 1GK2A 4APAA 1YISA 2PTSA 2PTRA 3NZ4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4CQ5 A;  2YII A;  2VD6 A;  3R6V A;  4NLE A;  2FUS A;  1W27 A;  5EYV A;  3CZO A;  1RE5 A;  2RJR A;  4BAA A;  2O7D A;  5F92 A;  1T6J A;  4FLC A;  1FUP A;  4EEI A;  1I0A A;  1HY1 A;  3E04 A;  4BAB A;  1FUR A;  2OHY A;  4APB A;  1U15 A;  5F91 A;  4FFX A;  3C8T A;  4C5U A;  5D6B A;  3UNV A;  1GKJ A;  3NO9 A;  1Q5N A;  1TJW A;  1C3U A;  2O7F A;  4HGV A;  1VDK A;  1B8F A;  5HW2 A;  1K7W A;  1DOF A;  1HY0 A;  3GTD A;  1K62 A;  3RRP A;  3OCF A;  3QBP A;  1TJU A;  1Y2M A;  2QGA B;  2O78 A;  2O7E A;  3KDY A;  4ADM A;  4V2R A;  1EB4 A;  3RD8 A;  1DCN A;  4C5S A;  1J3U A;  1C3C A;  1AUW A;  4C6G A;  2X75 A;  4V2Q A;  3KDZ A;  3R6Y A;  2NYN A;  4MX2 A;  4ADL A;  2RJS A;  1YFE A;  5EYT A;  2O6Y A;  3BHG A;  3OCE A;  3R6Q A;  2NYF A;  1GK3 A;  2J91 A;  4EFC A;  1T6P A;  1TJ7 A;  1XWO A;  1FUQ A;  1JSW A;  4C5R A;  1GKM A;  1FUO A;  3GZH A;  2HVG A;  1KQ7 A;  2O7B A;  2PFM A;  2E9F A;  1U16 A;  2PTQ A;  1YFM A;  2QVE A;  1TJV A;  4NSL A;  3TV2 A;  1GK2 A;  4APA A;  1YIS A;  2PTS A;  2PTR A;  3NZ4 A; 
#chains in the Genus database with same CATH topology
 2FIP A;  2B63 A;  2R7Z A;  2Y0N A;  1WCM A;  3U44 A;  1ZYM A;  1ZYR D;  4CQ5 A;  2YII A;  2LTH A;  2VD6 A;  3GTJ A;  4CEH A;  3R6V A;  2N3E A;  1YNN D;  3GTL A;  2FUS A;  4NLE A;  1I6V D;  1W27 A;  5EYV A;  2LKM B;  4A15 A;  3CZO A;  2VK9 A;  1RE5 A;  2RJR A;  2N1D B;  1YNJ D;  2A6H D;  2LPI A;  2CW0 D;  2F5J A;  4BAA A;  2O7D A;  5F92 A;  2JA7 A;  1T6J A;  4FLC A;  2LYI A;  1FUP A;  1Y1W A;  4EEI A;  2LPJ A;  1I0A A;  1HY1 A;  3E04 A;  4WNL A;  4QIW A;  1XL8 A;  2VL7 A;  4BAB A;  1FUR A;  1SMY D;  2JA5 A;  2OHY A;  4APB A;  4FBS A;  2A6E D;  2BE5 D;  1XLY A;  1U15 A;  2X0Q A;  2MX9 A;  3U4Q A;  1TWA A;  1XMD A;  4FFX A;  3C8T A;  4C5U A;  1TWH A;  5D6B A;  5F91 A;  2K3O A;  2MP0 A;  3UNV A;  1TWC A;  1GKJ A;  3NO9 A;  2X0O A;  1Q5N A;  1Y1V A;  1TJW A;  1C3U A;  3CRW 1;  2O7F A;  4HGV A;  1VDK A;  1B8F A;  2NVX A;  5HW2 A;  3GTM A;  2FIO A;  4CEJ A;  1K7W A;  3FKI A;  1DOF A;  1HY0 A;  1R9T A;  3GTD A;  3LR6 A;  4CEI A;  1K62 A;  3RRP A;  2A68 D;  3OCF A;  1Y2M A;  1TJU A;  2O78 A;  2QGA B;  3QBP A;  3LR8 A;  1I3Q A;  2O7E A;  3KDY A;  4ADM A;  4V2R A;  1IW7 D;  1EB4 A;  3RD8 A;  1DCN A;  4C5S A;  1J3U A;  1C3C A;  2R92 A;  2EZA A;  1AUW A;  4C6G A;  2X75 A;  2YU9 A;  2E2H A;  5H8W A;  4V2Q A;  3KDZ A;  3R6Y A;  1TWG A;  2FEL A;  2NYN A;  4MX2 A;  1HQM D;  2K3Q A;  3LRD A;  1YFE A;  2RJS A;  4ADL A;  5EYT A;  2EZC A;  3GTQ A;  2MQA A;  3GTG A;  2O6Y A;  3BHG A;  3OCE A;  3CQZ A;  1TWF A;  1EZB A;  3R6Q A;  2VUM A;  2NYF A;  3GTO A;  2O5J D;  2E2I A;  1GK3 A;  1XL7 A;  3CRV A;  2J91 A;  4EFC A;  1T6P A;  1TJ7 A;  3H0G A;  1XWO A;  2A69 D;  1FUQ A;  1JSW A;  2K3N A;  3EZE A;  4C5R A;  3GTK A;  1GKM A;  1FUO A;  3GZH A;  2HVG A;  5IZ2 A;  1KQ7 A;  2O7B A;  4C2M A;  2PFM A;  1XMC A;  2E9F A;  3LR2 A;  5M0J A;  2EZB A;  1U16 A;  2R93 A;  2JA6 A;  2PTQ A;  1YFM A;  3EZA A;  3GTP A;  2QVE A;  2MX8 A;  2X0P A;  1TJV A;  1K83 A;  5M0I A;  4NSL A;  3TV2 A;  1EZA A;  1SFO A;  1GK2 A;  2HWG A;  3EZB A;  4APA A;  2AQL A;  2HRO A;  1I50 A;  1YIS A;  2PTS A;  2NVY A;  2FEN A;  2PTR A;  3NZ4 A;  2VSF A; 
#chains in the Genus database with same CATH homology
 4CQ5 A;  2YII A;  2VD6 A;  3R6V A;  4NLE A;  2FUS A;  1W27 A;  5EYV A;  3CZO A;  1RE5 A;  2RJR A;  4BAA A;  2O7D A;  5F92 A;  1T6J A;  4FLC A;  1FUP A;  4EEI A;  1I0A A;  1HY1 A;  3E04 A;  4BAB A;  1FUR A;  2OHY A;  4APB A;  1U15 A;  5F91 A;  4FFX A;  3C8T A;  4C5U A;  5D6B A;  3UNV A;  1GKJ A;  3NO9 A;  1Q5N A;  1TJW A;  1C3U A;  2O7F A;  4HGV A;  1VDK A;  1B8F A;  5HW2 A;  1K7W A;  1DOF A;  1HY0 A;  3GTD A;  1K62 A;  3RRP A;  3OCF A;  3QBP A;  1TJU A;  1Y2M A;  2QGA B;  2O78 A;  2O7E A;  3KDY A;  4ADM A;  4V2R A;  1EB4 A;  3RD8 A;  1DCN A;  4C5S A;  1J3U A;  1C3C A;  1AUW A;  4C6G A;  2X75 A;  4V2Q A;  3KDZ A;  3R6Y A;  2NYN A;  4MX2 A;  4ADL A;  2RJS A;  1YFE A;  5EYT A;  2O6Y A;  3BHG A;  3OCE A;  3R6Q A;  2NYF A;  1GK3 A;  2J91 A;  4EFC A;  1T6P A;  1TJ7 A;  1XWO A;  1FUQ A;  1JSW A;  4C5R A;  1GKM A;  1FUO A;  3GZH A;  2HVG A;  1KQ7 A;  2O7B A;  2PFM A;  2E9F A;  1U16 A;  2PTQ A;  1YFM A;  2QVE A;  1TJV A;  4NSL A;  3TV2 A;  1GK2 A;  4APA A;  1YIS A;  2PTS A;  2PTR A;  3NZ4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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