1W27A

Phenylalanine ammonia-lyase (pal) from petroselinum crispum
Total Genus 254
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
254
sequence length
690
structure length
689
Chain Sequence
EDPLYWGIAAEAMTGSHLDEVKKMVAEYRKPVVKLGGETLTISQVAAISARDGSGVTVELSEAARAGVKASSDWVMDSMNKGTDSYGVTTGFGATSHRRTKQGGALQKELIRFLNAGIFGNGSDNTLPHSATRAAMLVRINTLLQGYSGIRFEILEAITKFLNQNITPCLPLRGTITDLVPLSYIAGLLTGRPNSKAVGPTGVILSPEEAFKLAGVEGGFFELQPKEGLALVNGTAVGSGMASMVLFEANILAVLAEVMSAIFAEVMQGKPEFTDHLTHKLKHHPGQIEAAAIMEHILDGSAYVKAAQKLHEMDPLQKPKQDRYALRTSPQWLGPQIEVIRSSTKMIEREINSVNDNPLIDVSRNKAIHGGNFQGTPIGVSMDNTRLAIAAIGKLMFAQFSELVNDFYNNGLPSNLSGGRNPSLDYGFKGAEIAMASYCSELQFLANPVTNHVQSAEQHNQDVNSLGLISSRKTSEAVEILKLMSTTFLVGLCQAIDLRHLEENLKSTVKNTVSSVAKRVLTMGVNGELHPSRFCEKDLLRVVDREYIFAYIDDPCSATYPLMQKLRQTLVEHALKNGDNERNLSTSIFQKIATFEDELKALLPKEVESARAALESGNPAIPNRIEECRSYPLYKFVRKELGTEYLTGEKVTSPGEEFEKVFIAMSKGEIIDPLLECLESWNGAPLPIC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis for the Entrance Into the Phenylpropanoid Metabolism Catalyzed by Phenylalanine Ammonia-Lyase
pubmed doi rcsb
source organism Petroselinum crispum
molecule tags Lyase
molecule keywords PHENYLALANINE AMMONIA-LYASE 1
total genus 254
structure length 689
sequence length 690
chains with identical sequence B
ec nomenclature ec 4.3.1.24: Phenylalanine ammonia-lyase.
pdb deposition date 2004-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.20 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 Phenylalanine ammonia-lyase 1; domain 3 1w27A03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1w27A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1w27A02
1FUQA 2J91A 3GTDA 5EYTA 2E9FA 2PTQA 5D6BA 1FURA 2O7BA 4ADLA 1K7WA 4BABA 1RE5A 4EEIA 4CQ5A 2QGAB 5F92A 4ADMA 1GKMA 4EFCA 3C8TA 3KDYA 1KQ7A 4C6GA 2O7FA 2X75A 2YIIA 3NZ4A 3BHGA 1YFEA 1C3UA 1AUWA 3TV2A 1J3UA 1Q5NA 5HW2A 1T6PA 1DOFA 1TJ7A 1U16A 4APAA 1B8FA 2FUSA 1TJWA 1U15A 4FFXA 3UNVA 4C5RA 4APBA 3OCFA 1VDKA 4NSLA 3R6VA 1DCNA 2NYNA 3RD8A 2O7EA 1GKJA 2PTRA 3KDZA 2O78A 1GK2A 4MX2A 3QBPA 3OCEA 4V2RA 2RJSA 3CZOA 1T6JA 3GZHA 3R6YA 1EB4A 1TJVA 2PTSA 2HVGA 1W27A 1C3CA 4C5UA 2O7DA 1HY1A 2RJRA 4V2QA 4BAAA 2O6YA 3E04A 1K62A 2NYFA 3NO9A 1FUPA 1YISA 1YFMA 5EYVA 1FUOA 3R6QA 2QVEA 4NLEA 2VD6A 3RRPA 1Y2MA 4HGVA 1GK3A 4FLCA 1HY0A 4C5SA 1XWOA 2PFMA 1JSWA 1TJUA 1I0AA 2OHYA 5F91A
chains in the Genus database with same CATH superfamily
2JA5A 1FUQA 2J91A 3GTDA 5EYTA 3GTGA 2E9FA 2PTQA 2FELA 2LKMB 3U44A 4CEJA 3GTOA 5IZ2A 2F5JA 5D6BA 1FURA 2X0PA 3LR2A 2O7BA 3CRW1 1TWCA 4ADLA 1K7WA 1HQMD 1TWAA 4BABA 1RE5A 4EEIA 2NVXA 3GTMA 2VSFA 4CQ5A 2FIOA 2QGAB 2YU9A 2LYIA 5H8WA 5F92A 4ADMA 1YNJD 3CQZA 1GKMA 4EFCA 3C8TA 3KDYA 3EZAA 1KQ7A 1K83A 1I6VD 1XMCA 3EZEA 4C6GA 1Y1WA 2O7FA 1ZYMA 2X75A 5M0IA 2YIIA 2VL7A 2N3EA 2MX8A 3NZ4A 2R7ZA 4A15A 2K3OA 3BHGA 3CRVA 2AQLA 4FBSA 1EZBA 1YFEA 2K3NA 2Y0NA 2O5JD 1XMDA 1C3UA 1AUWA 3TV2A 3GTPA 2E2HA 1J3UA 2A69D 2A6HD 1Q5NA 5HW2A 1T6PA 1DOFA 1TJ7A 1U16A 2NVYA 4QIWA 4APAA 1B8FA 5M0JA 1XLYA 2FUSA 1TJWA 1U15A 4FFXA 3FKIA 2JA7A 2VUMA 3EZBA 3UNVA 4CEHA 2EZBA 2LPIA 2MQAA 4C5RA 4APBA 3OCFA 4C2MA 2N1DB 3LR8A 2K3QA 1VDKA 3U4QA 4NSLA 3R6VA 2MX9A 1DCNA 3H0GA 2A68D 2VK9A 2NYNA 1TWGA 3RD8A 2O7EA 2LTHA 1GKJA 2PTRA 3KDZA 2JA6A 2O78A 1GK2A 4MX2A 3LR6A 3QBPA 3GTJA 3OCEA 4V2RA 2RJSA 1XL7A 3CZOA 1T6JA 1XL8A 3GZHA 3R6YA 2HWGA 2E2IA 2FENA 1EB4A 2CW0D 1TJVA 2PTSA 4WNLA 1YNND 2HVGA 1W27A 4C5UA 2B63A 1C3CA 2O7DA 2X0OA 1HY1A 2RJRA 1TWFA 2LPJA 4V2QA 3LRDA 4BAAA 2O6YA 2FIPA 3E04A 1K62A 2EZAA 2R92A 1ZYRD 2EZCA 1I50A 2NYFA 3NO9A 1SMYD 1IW7D 1FUPA 2X0QA 1YISA 2BE5D 1YFMA 5EYVA 2R93A 1FUOA 3R6QA 1R9TA 2QVEA 4NLEA 2VD6A 2A6ED 3RRPA 1Y2MA 2HROA 4HGVA 4CEIA 1GK3A 4FLCA 2MP0A 3GTQA 1HY0A 1Y1VA 1WCMA 4C5SA 1EZAA 1I3QA 1XWOA 3GTLA 2PFMA 1JSWA 1TJUA 1SFOA 1I0AA 1TWHA 2OHYA 5F91A 3GTKA
chains in the Genus database with same CATH topology
1FUQA 2J91A 3GTDA 5EYTA 2E9FA 2PTQA 5D6BA 1FURA 2O7BA 4ADLA 1K7WA 4BABA 1RE5A 4EEIA 4CQ5A 2QGAB 5F92A 4ADMA 1GKMA 4EFCA 3C8TA 3KDYA 1KQ7A 4C6GA 2O7FA 2X75A 2YIIA 3NZ4A 3BHGA 1YFEA 1C3UA 1AUWA 3TV2A 1J3UA 1Q5NA 5HW2A 1T6PA 1DOFA 1TJ7A 1U16A 4APAA 1B8FA 2FUSA 1TJWA 1U15A 4FFXA 3UNVA 4C5RA 4APBA 3OCFA 1VDKA 4NSLA 3R6VA 1DCNA 2NYNA 3RD8A 2O7EA 1GKJA 2PTRA 3KDZA 2O78A 1GK2A 4MX2A 3QBPA 3OCEA 4V2RA 2RJSA 3CZOA 1T6JA 3GZHA 3R6YA 1EB4A 1TJVA 2PTSA 2HVGA 1W27A 1C3CA 4C5UA 2O7DA 1HY1A 2RJRA 4V2QA 4BAAA 2O6YA 3E04A 1K62A 2NYFA 3NO9A 1FUPA 1YISA 1YFMA 5EYVA 1FUOA 3R6QA 2QVEA 4NLEA 2VD6A 3RRPA 1Y2MA 4HGVA 1GK3A 4FLCA 1HY0A 4C5SA 1XWOA 2PFMA 1JSWA 1TJUA 1I0AA 2OHYA 5F91A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FUQ A;  2J91 A;  3GTD A;  5EYT A;  2E9F A;  2PTQ A;  5D6B A;  1FUR A;  2O7B A;  4ADL A;  1K7W A;  4BAB A;  1RE5 A;  4EEI A;  4CQ5 A;  2QGA B;  5F92 A;  4ADM A;  1GKM A;  4EFC A;  3C8T A;  3KDY A;  1KQ7 A;  4C6G A;  2O7F A;  2X75 A;  2YII A;  3NZ4 A;  3BHG A;  1YFE A;  1C3U A;  1AUW A;  3TV2 A;  1J3U A;  1Q5N A;  5HW2 A;  1T6P A;  1DOF A;  1TJ7 A;  1U16 A;  4APA A;  1B8F A;  2FUS A;  1TJW A;  1U15 A;  4FFX A;  3UNV A;  4C5R A;  4APB A;  3OCF A;  1VDK A;  4NSL A;  3R6V A;  1DCN A;  2NYN A;  3RD8 A;  2O7E A;  1GKJ A;  2PTR A;  3KDZ A;  2O78 A;  1GK2 A;  4MX2 A;  3QBP A;  3OCE A;  4V2R A;  2RJS A;  3CZO A;  1T6J A;  3GZH A;  3R6Y A;  1EB4 A;  1TJV A;  2PTS A;  2HVG A;  1W27 A;  1C3C A;  4C5U A;  2O7D A;  1HY1 A;  2RJR A;  4V2Q A;  4BAA A;  2O6Y A;  3E04 A;  1K62 A;  2NYF A;  3NO9 A;  1FUP A;  1YIS A;  1YFM A;  5EYV A;  1FUO A;  3R6Q A;  2QVE A;  4NLE A;  2VD6 A;  3RRP A;  1Y2M A;  4HGV A;  1GK3 A;  4FLC A;  1HY0 A;  4C5S A;  1XWO A;  2PFM A;  1JSW A;  1TJU A;  1I0A A;  2OHY A;  5F91 A; 
#chains in the Genus database with same CATH topology
 2JA5 A;  1FUQ A;  2J91 A;  3GTD A;  5EYT A;  3GTG A;  2E9F A;  2PTQ A;  2FEL A;  2LKM B;  3U44 A;  4CEJ A;  3GTO A;  5IZ2 A;  2F5J A;  5D6B A;  1FUR A;  2X0P A;  3LR2 A;  2O7B A;  3CRW 1;  1TWC A;  4ADL A;  1K7W A;  1HQM D;  1TWA A;  4BAB A;  1RE5 A;  4EEI A;  2NVX A;  3GTM A;  2VSF A;  4CQ5 A;  2FIO A;  2QGA B;  2YU9 A;  2LYI A;  5H8W A;  5F92 A;  4ADM A;  1YNJ D;  3CQZ A;  1GKM A;  4EFC A;  3C8T A;  3KDY A;  3EZA A;  1KQ7 A;  1K83 A;  1I6V D;  1XMC A;  3EZE A;  4C6G A;  1Y1W A;  2O7F A;  1ZYM A;  2X75 A;  5M0I A;  2YII A;  2VL7 A;  2N3E A;  2MX8 A;  3NZ4 A;  2R7Z A;  4A15 A;  2K3O A;  3BHG A;  3CRV A;  2AQL A;  4FBS A;  1EZB A;  1YFE A;  2K3N A;  2Y0N A;  2O5J D;  1XMD A;  1C3U A;  1AUW A;  3TV2 A;  3GTP A;  2E2H A;  1J3U A;  2A69 D;  2A6H D;  1Q5N A;  5HW2 A;  1T6P A;  1DOF A;  1TJ7 A;  1U16 A;  2NVY A;  4QIW A;  4APA A;  1B8F A;  5M0J A;  1XLY A;  2FUS A;  1TJW A;  1U15 A;  4FFX A;  3FKI A;  2JA7 A;  2VUM A;  3EZB A;  3UNV A;  4CEH A;  2EZB A;  2LPI A;  2MQA A;  4C5R A;  4APB A;  3OCF A;  4C2M A;  2N1D B;  3LR8 A;  2K3Q A;  1VDK A;  3U4Q A;  4NSL A;  3R6V A;  2MX9 A;  1DCN A;  3H0G A;  2A68 D;  2VK9 A;  2NYN A;  1TWG A;  3RD8 A;  2O7E A;  2LTH A;  1GKJ A;  2PTR A;  3KDZ A;  2JA6 A;  2O78 A;  1GK2 A;  4MX2 A;  3LR6 A;  3QBP A;  3GTJ A;  3OCE A;  4V2R A;  2RJS A;  1XL7 A;  3CZO A;  1T6J A;  1XL8 A;  3GZH A;  3R6Y A;  2HWG A;  2E2I A;  2FEN A;  1EB4 A;  2CW0 D;  1TJV A;  2PTS A;  4WNL A;  1YNN D;  2HVG A;  1W27 A;  4C5U A;  2B63 A;  1C3C A;  2O7D A;  2X0O A;  1HY1 A;  2RJR A;  1TWF A;  2LPJ A;  4V2Q A;  3LRD A;  4BAA A;  2O6Y A;  2FIP A;  3E04 A;  1K62 A;  2EZA A;  2R92 A;  1ZYR D;  2EZC A;  1I50 A;  2NYF A;  3NO9 A;  1SMY D;  1IW7 D;  1FUP A;  2X0Q A;  1YIS A;  2BE5 D;  1YFM A;  5EYV A;  2R93 A;  1FUO A;  3R6Q A;  1R9T A;  2QVE A;  4NLE A;  2VD6 A;  2A6E D;  3RRP A;  1Y2M A;  2HRO A;  4HGV A;  4CEI A;  1GK3 A;  4FLC A;  2MP0 A;  3GTQ A;  1HY0 A;  1Y1V A;  1WCM A;  4C5S A;  1EZA A;  1I3Q A;  1XWO A;  3GTL A;  2PFM A;  1JSW A;  1TJU A;  1SFO A;  1I0A A;  1TWH A;  2OHY A;  5F91 A;  3GTK A; 
#chains in the Genus database with same CATH homology
 1FUQ A;  2J91 A;  3GTD A;  5EYT A;  2E9F A;  2PTQ A;  5D6B A;  1FUR A;  2O7B A;  4ADL A;  1K7W A;  4BAB A;  1RE5 A;  4EEI A;  4CQ5 A;  2QGA B;  5F92 A;  4ADM A;  1GKM A;  4EFC A;  3C8T A;  3KDY A;  1KQ7 A;  4C6G A;  2O7F A;  2X75 A;  2YII A;  3NZ4 A;  3BHG A;  1YFE A;  1C3U A;  1AUW A;  3TV2 A;  1J3U A;  1Q5N A;  5HW2 A;  1T6P A;  1DOF A;  1TJ7 A;  1U16 A;  4APA A;  1B8F A;  2FUS A;  1TJW A;  1U15 A;  4FFX A;  3UNV A;  4C5R A;  4APB A;  3OCF A;  1VDK A;  4NSL A;  3R6V A;  1DCN A;  2NYN A;  3RD8 A;  2O7E A;  1GKJ A;  2PTR A;  3KDZ A;  2O78 A;  1GK2 A;  4MX2 A;  3QBP A;  3OCE A;  4V2R A;  2RJS A;  3CZO A;  1T6J A;  3GZH A;  3R6Y A;  1EB4 A;  1TJV A;  2PTS A;  2HVG A;  1W27 A;  1C3C A;  4C5U A;  2O7D A;  1HY1 A;  2RJR A;  4V2Q A;  4BAA A;  2O6Y A;  3E04 A;  1K62 A;  2NYF A;  3NO9 A;  1FUP A;  1YIS A;  1YFM A;  5EYV A;  1FUO A;  3R6Q A;  2QVE A;  4NLE A;  2VD6 A;  3RRP A;  1Y2M A;  4HGV A;  1GK3 A;  4FLC A;  1HY0 A;  4C5S A;  1XWO A;  2PFM A;  1JSW A;  1TJU A;  1I0A A;  2OHY A;  5F91 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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