1W27A

Phenylalanine ammonia-lyase (pal) from petroselinum crispum
Total Genus 254
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
254
sequence length
690
structure length
689
Chain Sequence
b'EDPLYWGIAAEAMTGSHLDEVKKMVAEYRKPVVKLGGETLTISQVAAISARDGSGVTVELSEAARAGVKASSDWVMDSMNKGTDSYGVTTGFGATSHRRTKQGGALQKELIRFLNAGIFGNGSDNTLPHSATRAAMLVRINTLLQGYSGIRFEILEAITKFLNQNITPCLPLRGTITDLVPLSYIAGLLTGRPNSKAVGPTGVILSPEEAFKLAGVEGGFFELQPKEGLALVNGTAVGSGMASMVLFEANILAVLAEVMSAIFAEVMQGKPEFTDHLTHKLKHHPGQIEAAAIMEHILDGSAYVKAAQKLHEMDPLQKPKQDRYALRTSPQWLGPQIEVIRSSTKMIEREINSVNDNPLIDVSRNKAIHGGNFQGTPIGVSMDNTRLAIAAIGKLMFAQFSELVNDFYNNGLPSNLSGGRNPSLDYGFKGAEIAMASYCSELQFLANPVTNHVQSAEQHNQDVNSLGLISSRKTSEAVEILKLMSTTFLVGLCQAIDLRHLEENLKSTVKNTVSSVAKRVLTMGVNGELHPSRFCEKDLLRVVDREYIFAYIDDPCSATYPLMQKLRQTLVEHALKNGDNERNLSTSIFQKIATFEDELKALLPKEVESARAALESGNPAIPNRIEECRSYPLYKFVRKELGTEYLTGEKVTSPGEEFEKVFIAMSKGEIIDPLLECLESWNGAPLPIC'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords PHENYLALANINE AMMONIA-LYASE 1
publication title Structural Basis for the Entrance Into the Phenylpropanoid Metabolism Catalyzed by Phenylalanine Ammonia-Lyase
pubmed doi rcsb
source organism Petroselinum crispum
molecule tags Lyase
total genus 254
structure length 689
sequence length 690
chains with identical sequence B
ec nomenclature ec 4.3.1.24: Phenylalanine ammonia-lyase.
pdb deposition date 2004-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.20 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 Phenylalanine ammonia-lyase 1; domain 3 1w27A03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1w27A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1w27A02
4C5SA 2PTQA 2NYFA 2PFMA 3E04A 3GTDA 1TJWA 1TJUA 1AUWA 3KDYA 1FUQA 1GK3A 1Y2MA 1T6PA 4NLEA 5D6BA 1T6JA 4V2QA 1YFEA 2O7EA 4BAAA 3RRPA 1W27A 1EB4A 2FUSA 1JSWA 1VDKA 2YIIA 4C5RA 3CZOA 1TJVA 3RD8A 3UNVA 2OHYA 2O7FA 2X75A 1U16A 1RE5A 4FFXA 2O6YA 2HVGA 4C5UA 1DOFA 2QGAB 4C6GA 4CQ5A 1GK2A 5EYVA 3R6QA 2NYNA 4HGVA 3OCEA 4FLCA 3NZ4A 1GKMA 1Q5NA 4APBA 3GZHA 1HY1A 2PTRA 2RJRA 5EYTA 1YFMA 3KDZA 4BABA 4EFCA 1TJ7A 1K7WA 2O78A 2J91A 3OCFA 4ADLA 3BHGA 4EEIA 1J3UA 1C3UA 1KQ7A 2O7BA 1FUPA 1DCNA 3NO9A 1XWOA 1B8FA 1HY0A 1K62A 3R6YA 5HW2A 5F92A 2QVEA 1I0AA 4ADMA 1FURA 4NSLA 5F91A 2VD6A 4V2RA 1YISA 4MX2A 3TV2A 2O7DA 1C3CA 2E9FA 1GKJA 2RJSA 4APAA 3R6VA 1FUOA 3QBPA 3C8TA 2PTSA 1U15A
chains in the Genus database with same CATH superfamily
4C5SA 2MP0A 2PTQA 2N1DB 2NYFA 3LR2A 2PFMA 3E04A 1TJWA 2HROA 1TWAA 2A6ED 2MX9A 1TJUA 3GTDA 1AUWA 1TWGA 2VUMA 3KDYA 2K3QA 1FUQA 2FIPA 3GTOA 1GK3A 1Y2MA 1T6PA 1R9TA 3H0GA 1I3QA 4FBSA 2VL7A 3GTKA 3CQZA 3FKIA 4NLEA 5D6BA 2VK9A 3GTQA 2JA6A 3EZEA 1T6JA 4A15A 2A68D 2A6HD 2MX8A 5H8WA 4V2QA 1YFEA 2O7EA 4BAAA 3RRPA 1TWCA 3CRW1 1W27A 1HQMD 1EB4A 2FUSA 1JSWA 1VDKA 2YIIA 2AQLA 4C5RA 2O5JD 3CZOA 1TJVA 3RD8A 3GTMA 3UNVA 2A69D 5M0IA 1K83A 2OHYA 2O7FA 2EZCA 1I6VD 2X75A 3GTPA 1U16A 1IW7D 2R7ZA 2FELA 2LYIA 1RE5A 4FFXA 2F5JA 2O6YA 3GTGA 2HVGA 4C5UA 1TWFA 1DOFA 2CW0D 2JA5A 2QGAB 3EZBA 4C6GA 1XLYA 2K3OA 4CQ5A 3U44A 1GK2A 5EYVA 3R6QA 4WNLA 2NYNA 4HGVA 2JA7A 1EZAA 2N3EA 1XMCA 3OCEA 4FLCA 1GKMA 4C2MA 4QIWA 1WCMA 1Q5NA 3EZAA 4APBA 1SMYD 2EZAA 1HY1A 2PTRA 3GZHA 2RJRA 5EYTA 2YU9A 1SFOA 2R92A 2X0OA 2LKMB 1YFMA 4BABA 3KDZA 4EFCA 1TJ7A 1K7WA 2O78A 2FIOA 4CEIA 1Y1VA 2B63A 2E2IA 2EZBA 1TWHA 2J91A 2VSFA 2MQAA 3OCFA 4ADLA 2K3NA 5M0JA 1Y1WA 3BHGA 2NVXA 2PTSA 4EEIA 1J3UA 1ZYMA 2Y0NA 2E2HA 1C3UA 2R93A 1DCNA 1FUPA 1KQ7A 2O7BA 1XL8A 2X0PA 3NO9A 1XWOA 2LTHA 3GTLA 1B8FA 1HY0A 1K62A 1XL7A 3R6YA 5HW2A 5F92A 2QVEA 1I0AA 2X0QA 1ZYRD 2BE5D 2LPJA 1YNND 4CEJA 4ADMA 3LR6A 1FURA 1I50A 3GTJA 3LR8A 2LPIA 5IZ2A 4NSLA 2VD6A 5F91A 4V2RA 1YISA 2FENA 4MX2A 3CRVA 3TV2A 2O7DA 1C3CA 3U4QA 2E9FA 2HWGA 1GKJA 2RJSA 4APAA 3R6VA 1YNJD 3LRDA 4CEHA 1FUOA 3QBPA 3C8TA 2NVYA 3NZ4A 1EZBA 1XMDA 1U15A
chains in the Genus database with same CATH topology
4C5SA 2PTQA 2NYFA 2PFMA 3E04A 3GTDA 1TJWA 1TJUA 1AUWA 3KDYA 1FUQA 1GK3A 1Y2MA 1T6PA 4NLEA 5D6BA 1T6JA 4V2QA 1YFEA 2O7EA 4BAAA 3RRPA 1W27A 1EB4A 2FUSA 1JSWA 1VDKA 2YIIA 4C5RA 3CZOA 1TJVA 3RD8A 3UNVA 2OHYA 2O7FA 2X75A 1U16A 1RE5A 4FFXA 2O6YA 2HVGA 4C5UA 1DOFA 2QGAB 4C6GA 4CQ5A 1GK2A 5EYVA 3R6QA 2NYNA 4HGVA 3OCEA 4FLCA 3NZ4A 1GKMA 1Q5NA 4APBA 3GZHA 1HY1A 2PTRA 2RJRA 5EYTA 1YFMA 3KDZA 4BABA 4EFCA 1TJ7A 1K7WA 2O78A 2J91A 3OCFA 4ADLA 3BHGA 4EEIA 1J3UA 1C3UA 1KQ7A 2O7BA 1FUPA 1DCNA 3NO9A 1XWOA 1B8FA 1HY0A 1K62A 3R6YA 5HW2A 5F92A 2QVEA 1I0AA 4ADMA 1FURA 4NSLA 5F91A 2VD6A 4V2RA 1YISA 4MX2A 3TV2A 2O7DA 1C3CA 2E9FA 1GKJA 2RJSA 4APAA 3R6VA 1FUOA 3QBPA 3C8TA 2PTSA 1U15A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4C5S A;  2PTQ A;  2NYF A;  2PFM A;  3E04 A;  3GTD A;  1TJW A;  1TJU A;  1AUW A;  3KDY A;  1FUQ A;  1GK3 A;  1Y2M A;  1T6P A;  4NLE A;  5D6B A;  1T6J A;  4V2Q A;  1YFE A;  2O7E A;  4BAA A;  3RRP A;  1W27 A;  1EB4 A;  2FUS A;  1JSW A;  1VDK A;  2YII A;  4C5R A;  3CZO A;  1TJV A;  3RD8 A;  3UNV A;  2OHY A;  2O7F A;  2X75 A;  1U16 A;  1RE5 A;  4FFX A;  2O6Y A;  2HVG A;  4C5U A;  1DOF A;  2QGA B;  4C6G A;  4CQ5 A;  1GK2 A;  5EYV A;  3R6Q A;  2NYN A;  4HGV A;  3OCE A;  4FLC A;  3NZ4 A;  1GKM A;  1Q5N A;  4APB A;  3GZH A;  1HY1 A;  2PTR A;  2RJR A;  5EYT A;  1YFM A;  3KDZ A;  4BAB A;  4EFC A;  1TJ7 A;  1K7W A;  2O78 A;  2J91 A;  3OCF A;  4ADL A;  3BHG A;  4EEI A;  1J3U A;  1C3U A;  1KQ7 A;  2O7B A;  1FUP A;  1DCN A;  3NO9 A;  1XWO A;  1B8F A;  1HY0 A;  1K62 A;  3R6Y A;  5HW2 A;  5F92 A;  2QVE A;  1I0A A;  4ADM A;  1FUR A;  4NSL A;  5F91 A;  2VD6 A;  4V2R A;  1YIS A;  4MX2 A;  3TV2 A;  2O7D A;  1C3C A;  2E9F A;  1GKJ A;  2RJS A;  4APA A;  3R6V A;  1FUO A;  3QBP A;  3C8T A;  2PTS A;  1U15 A; 
#chains in the Genus database with same CATH topology
 4C5S A;  2MP0 A;  2PTQ A;  2N1D B;  2NYF A;  3LR2 A;  2PFM A;  3E04 A;  1TJW A;  2HRO A;  1TWA A;  2A6E D;  2MX9 A;  1TJU A;  3GTD A;  1AUW A;  1TWG A;  2VUM A;  3KDY A;  2K3Q A;  1FUQ A;  2FIP A;  3GTO A;  1GK3 A;  1Y2M A;  1T6P A;  1R9T A;  3H0G A;  1I3Q A;  4FBS A;  2VL7 A;  3GTK A;  3CQZ A;  3FKI A;  4NLE A;  5D6B A;  2VK9 A;  3GTQ A;  2JA6 A;  3EZE A;  1T6J A;  4A15 A;  2A68 D;  2A6H D;  2MX8 A;  5H8W A;  4V2Q A;  1YFE A;  2O7E A;  4BAA A;  3RRP A;  1TWC A;  3CRW 1;  1W27 A;  1HQM D;  1EB4 A;  2FUS A;  1JSW A;  1VDK A;  2YII A;  2AQL A;  4C5R A;  2O5J D;  3CZO A;  1TJV A;  3RD8 A;  3GTM A;  3UNV A;  2A69 D;  5M0I A;  1K83 A;  2OHY A;  2O7F A;  2EZC A;  1I6V D;  2X75 A;  3GTP A;  1U16 A;  1IW7 D;  2R7Z A;  2FEL A;  2LYI A;  1RE5 A;  4FFX A;  2F5J A;  2O6Y A;  3GTG A;  2HVG A;  4C5U A;  1TWF A;  1DOF A;  2CW0 D;  2JA5 A;  2QGA B;  3EZB A;  4C6G A;  1XLY A;  2K3O A;  4CQ5 A;  3U44 A;  1GK2 A;  5EYV A;  3R6Q A;  4WNL A;  2NYN A;  4HGV A;  2JA7 A;  1EZA A;  2N3E A;  1XMC A;  3OCE A;  4FLC A;  1GKM A;  4C2M A;  4QIW A;  1WCM A;  1Q5N A;  3EZA A;  4APB A;  1SMY D;  2EZA A;  1HY1 A;  2PTR A;  3GZH A;  2RJR A;  5EYT A;  2YU9 A;  1SFO A;  2R92 A;  2X0O A;  2LKM B;  1YFM A;  4BAB A;  3KDZ A;  4EFC A;  1TJ7 A;  1K7W A;  2O78 A;  2FIO A;  4CEI A;  1Y1V A;  2B63 A;  2E2I A;  2EZB A;  1TWH A;  2J91 A;  2VSF A;  2MQA A;  3OCF A;  4ADL A;  2K3N A;  5M0J A;  1Y1W A;  3BHG A;  2NVX A;  2PTS A;  4EEI A;  1J3U A;  1ZYM A;  2Y0N A;  2E2H A;  1C3U A;  2R93 A;  1DCN A;  1FUP A;  1KQ7 A;  2O7B A;  1XL8 A;  2X0P A;  3NO9 A;  1XWO A;  2LTH A;  3GTL A;  1B8F A;  1HY0 A;  1K62 A;  1XL7 A;  3R6Y A;  5HW2 A;  5F92 A;  2QVE A;  1I0A A;  2X0Q A;  1ZYR D;  2BE5 D;  2LPJ A;  1YNN D;  4CEJ A;  4ADM A;  3LR6 A;  1FUR A;  1I50 A;  3GTJ A;  3LR8 A;  2LPI A;  5IZ2 A;  4NSL A;  2VD6 A;  5F91 A;  4V2R A;  1YIS A;  2FEN A;  4MX2 A;  3CRV A;  3TV2 A;  2O7D A;  1C3C A;  3U4Q A;  2E9F A;  2HWG A;  1GKJ A;  2RJS A;  4APA A;  3R6V A;  1YNJ D;  3LRD A;  4CEH A;  1FUO A;  3QBP A;  3C8T A;  2NVY A;  3NZ4 A;  1EZB A;  1XMD A;  1U15 A; 
#chains in the Genus database with same CATH homology
 4C5S A;  2PTQ A;  2NYF A;  2PFM A;  3E04 A;  3GTD A;  1TJW A;  1TJU A;  1AUW A;  3KDY A;  1FUQ A;  1GK3 A;  1Y2M A;  1T6P A;  4NLE A;  5D6B A;  1T6J A;  4V2Q A;  1YFE A;  2O7E A;  4BAA A;  3RRP A;  1W27 A;  1EB4 A;  2FUS A;  1JSW A;  1VDK A;  2YII A;  4C5R A;  3CZO A;  1TJV A;  3RD8 A;  3UNV A;  2OHY A;  2O7F A;  2X75 A;  1U16 A;  1RE5 A;  4FFX A;  2O6Y A;  2HVG A;  4C5U A;  1DOF A;  2QGA B;  4C6G A;  4CQ5 A;  1GK2 A;  5EYV A;  3R6Q A;  2NYN A;  4HGV A;  3OCE A;  4FLC A;  3NZ4 A;  1GKM A;  1Q5N A;  4APB A;  3GZH A;  1HY1 A;  2PTR A;  2RJR A;  5EYT A;  1YFM A;  3KDZ A;  4BAB A;  4EFC A;  1TJ7 A;  1K7W A;  2O78 A;  2J91 A;  3OCF A;  4ADL A;  3BHG A;  4EEI A;  1J3U A;  1C3U A;  1KQ7 A;  2O7B A;  1FUP A;  1DCN A;  3NO9 A;  1XWO A;  1B8F A;  1HY0 A;  1K62 A;  3R6Y A;  5HW2 A;  5F92 A;  2QVE A;  1I0A A;  4ADM A;  1FUR A;  4NSL A;  5F91 A;  2VD6 A;  4V2R A;  1YIS A;  4MX2 A;  3TV2 A;  2O7D A;  1C3C A;  2E9F A;  1GKJ A;  2RJS A;  4APA A;  3R6V A;  1FUO A;  3QBP A;  3C8T A;  2PTS A;  1U15 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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