2MP0A

Protein phosphorylation upon a fleeting encounter
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
249
structure length
249
Chain Sequence
MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRAVQEQVASE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords Phosphoenolpyruvate-protein phosphotransferase
publication title Visualizing an Ultra-Weak Protein-Protein Interaction in Phosphorylation Signaling
doi rcsb
source organism Escherichia coli
total genus 74
structure length 249
sequence length 249
ec nomenclature ec 2.7.3.9: Phosphoenolpyruvate--protein phosphotransferase.
pdb deposition date 2014-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00391 PEP-utilizers PEP-utilising enzyme, mobile domain
A PF05524 PEP-utilisers_N PEP-utilising enzyme, N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.10 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 PtsI, HPr-binding domain 2mp0A02
3.50.30.10 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Phosphohistidine domain 2mp0A01
3T0TA 3EZEA 3T07A 2MP0A 2HI6A 2FM4A 2R82A 1DIKA 1ZYMA 3EZAA 1KC7A 2HROA 1EZAA 2EZCA 2E28A 2OLSA 2EZAA 1KBLA 1GGOA 1VBHA 1VBGA 1EZBA 3EZBA 1JDEA 2EZBA 3T05A 2HWGA 2X0SA 5JVLA 2DIKA
chains in the Genus database with same CATH superfamily
4C99A 3LR2A 4TJXA 2XEJA 4C9EA 3TLZA 3TYXA 4MCQA 4C5UA 4H1HA 3GTQA 4W9YA 4C8UA 2HWGA 3EZEA 3U4QA 4COGA 2R82A 1CX8A 1KC7A 4MCPA 3D7DA 3K4IA 4LQGA 3FF3A 4CDKA 4C84A 4C9AA 4P4EA 1JDBC 2K3NA 1EZBA 4CZ1A 1R61A 1Y1WA 1Y9ZA 2MX9A 2FIPA 1M6VB 2R7ZA 1EZAA 2EZCA 4P4IA 2X0OA 2Y0NA 4NGPA 3BI0A 1DE4C 4P4JA 2K3OA 4P4FA 1ZYRD 2A68D 1NXJA 3FECA 4C8FA 4MCSA 3TLAA 2LYIA 5IZ2A 1DIKA 2N1DB 4OC1A 4CDJA 4X3RA 3D7GA 2VUMA 1C30B 1SFOA 2EK8A 1TWFA 5F5XA 3TLGB 5IB9A 4MCRA 2XEIA 3TLCA 2O5JD 3NOJA 1CE8B 2JBJA 2NVYA 3T5MA 4NGSA 3BI1A 3KASA 4CEHA 4P45A 4BABA 4BAAA 2YJTA 2AQLA 1VBGA 4NGRA 2CIJA 2C6PA 4CEJA 3T07A 1YNJD 1T6PA 2AUNA 4V2QA 4C8AA 3SJGA 3KRVA 3VTAA 1T6JA 2LTHA 3H0GA 2X0QA 4EYSA 4YN3A 3IWWA 2FIOA 5F9MA 4C9RA 2PCNA 2PVVA 4C5SA 4TWEA 1GGOA 2XEFA 1BXRB 4C8CA 2YU9A 4V2RA 5JVLA 2JA5A 1Y2MA 2DIKA 2PVWA 5JYBA 2BE5D 2EK9A 3GTOA 3GTLA 4IIYA 4P4DA 1V6CA 2C6CA 2OR4A 2K3QA 2JA6A 3GTGA 4OC2A 3GTPA 3GTKA 1WVMA 3FKIA 2N3EA 1ZRSA 3SJFA 1TWCA 5F1YA 3U1BA 3GTMA 3I6SA 1R9TA 3C8OA 2NVXA 3BHXA 1HQMD 4IIXA 3LRDA 3TLBA 5D29A 2C6GA 2B63A 4C85A 3G23A 2XEGA 3FEEA 3NZ4A 1K83A 2CW0D 3U44A 5IR2A 1KBLA 1Y1VA 3FEDA 3GTJA 2AUMA 3RBUA 3EZBA 1C3OB 4OMEA 1Q5XA 5K99A 4E5SA 4OC0A 1Z8LA 4CEIA 2HI6A 1I6VD 4COBA 4C2MA 2E2IA 1I50A 2D0PA 4JYWA 4C6GA 4MI1A 1WCMA 2YJVA 2LKMB 2E2HA 4CQ5A 2C5QA 4C8PA 1TWAA 4M8DA 4NGMA 3EZAA 3S9MA 1W27A 2A6ED 5F09A 1TWHA 3SR3A 1J3LA 1JDEA 4INJA 1TWGA 2LPJA 3TLYA 4TJVA 3S9LA 4OC5A 1SMYD 3I74A 2MP0A 3GJZA 1IW7D 1A9XB 3D7FA 1ZL0A 2R92A 4NGTA 4C9VA 4FBSA 2B0AA 3SJEA 3T05A 4C8TA 3CQZA 3D7HA 1ZYMA 3BXMA 2MQAA 4OC3A 2FM4A 4J0NA 4C5RA 3K9TA 2OLSA 4P4BA 4OC4A 4NGQA 1CS0B 2LPIA 1VBHA 4CO9A 2F5JA 1VI4A 4P44A 2X0SA 2JBKA 3T0TA 3LR6A 4E94A 1NBWA 2JA7A 2A69D 3EIFA 2HROA 2E28A 4KNGE 2EZAA 2VK9A 4JVOA 2X0PA 2YIIA 3TLEA 2R93A 1I3QA 3SJXA 2A6HD 3IIBA 4QIWA 2GP4A 2OOTA 3LR8A 3ICUA 3S9NA 4NGNA 1T36B 5ELYA 4C9UA 2D0OA 1XF1A 5FD8A 1YNND 2MX8A 1KEEB 4C86A 3TLGA 4MJXA 2EZBA 4JZ0A
chains in the Genus database with same CATH topology
3T0TA 3EZEA 3T07A 2MP0A 2HI6A 2FM4A 2R82A 1DIKA 1ZYMA 3EZAA 1KC7A 2HROA 1EZAA 2EZCA 2E28A 2OLSA 2EZAA 1KBLA 1GGOA 1VBHA 1VBGA 1EZBA 3EZBA 1JDEA 2EZBA 3T05A 2HWGA 2X0SA 5JVLA 2DIKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3T0T A;  3EZE A;  3T07 A;  2MP0 A;  2HI6 A;  2FM4 A;  2R82 A;  1DIK A;  1ZYM A;  3EZA A;  1KC7 A;  2HRO A;  1EZA A;  2EZC A;  2E28 A;  2OLS A;  2EZA A;  1KBL A;  1GGO A;  1VBH A;  1VBG A;  1EZB A;  3EZB A;  1JDE A;  2EZB A;  3T05 A;  2HWG A;  2X0S A;  5JVL A;  2DIK A; 
#chains in the Genus database with same CATH topology
 4C99 A;  3LR2 A;  4TJX A;  2XEJ A;  4C9E A;  3TLZ A;  3TYX A;  4MCQ A;  4C5U A;  4H1H A;  3GTQ A;  4W9Y A;  4C8U A;  2HWG A;  3EZE A;  3U4Q A;  4COG A;  2R82 A;  1CX8 A;  1KC7 A;  4MCP A;  3D7D A;  3K4I A;  4LQG A;  3FF3 A;  4CDK A;  4C84 A;  4C9A A;  4P4E A;  1JDB C;  2K3N A;  1EZB A;  4CZ1 A;  1R61 A;  1Y1W A;  1Y9Z A;  2MX9 A;  2FIP A;  1M6V B;  2R7Z A;  1EZA A;  2EZC A;  4P4I A;  2X0O A;  2Y0N A;  4NGP A;  3BI0 A;  1DE4 C;  4P4J A;  2K3O A;  4P4F A;  1ZYR D;  2A68 D;  1NXJ A;  3FEC A;  4C8F A;  4MCS A;  3TLA A;  2LYI A;  5IZ2 A;  1DIK A;  2N1D B;  4OC1 A;  4CDJ A;  4X3R A;  3D7G A;  2VUM A;  1C30 B;  1SFO A;  2EK8 A;  1TWF A;  5F5X A;  3TLG B;  5IB9 A;  4MCR A;  2XEI A;  3TLC A;  2O5J D;  3NOJ A;  1CE8 B;  2JBJ A;  2NVY A;  3T5M A;  4NGS A;  3BI1 A;  3KAS A;  4CEH A;  4P45 A;  4BAB A;  4BAA A;  2YJT A;  2AQL A;  1VBG A;  4NGR A;  2CIJ A;  2C6P A;  4CEJ A;  3T07 A;  1YNJ D;  1T6P A;  2AUN A;  4V2Q A;  4C8A A;  3SJG A;  3KRV A;  3VTA A;  1T6J A;  2LTH A;  3H0G A;  2X0Q A;  4EYS A;  4YN3 A;  3IWW A;  2FIO A;  5F9M A;  4C9R A;  2PCN A;  2PVV A;  4C5S A;  4TWE A;  1GGO A;  2XEF A;  1BXR B;  4C8C A;  2YU9 A;  4V2R A;  5JVL A;  2JA5 A;  1Y2M A;  2DIK A;  2PVW A;  5JYB A;  2BE5 D;  2EK9 A;  3GTO A;  3GTL A;  4IIY A;  4P4D A;  1V6C A;  2C6C A;  2OR4 A;  2K3Q A;  2JA6 A;  3GTG A;  4OC2 A;  3GTP A;  3GTK A;  1WVM A;  3FKI A;  2N3E A;  1ZRS A;  3SJF A;  1TWC A;  5F1Y A;  3U1B A;  3GTM A;  3I6S A;  1R9T A;  3C8O A;  2NVX A;  3BHX A;  1HQM D;  4IIX A;  3LRD A;  3TLB A;  5D29 A;  2C6G A;  2B63 A;  4C85 A;  3G23 A;  2XEG A;  3FEE A;  3NZ4 A;  1K83 A;  2CW0 D;  3U44 A;  5IR2 A;  1KBL A;  1Y1V A;  3FED A;  3GTJ A;  2AUM A;  3RBU A;  3EZB A;  1C3O B;  4OME A;  1Q5X A;  5K99 A;  4E5S A;  4OC0 A;  1Z8L A;  4CEI A;  2HI6 A;  1I6V D;  4COB A;  4C2M A;  2E2I A;  1I50 A;  2D0P A;  4JYW A;  4C6G A;  4MI1 A;  1WCM A;  2YJV A;  2LKM B;  2E2H A;  4CQ5 A;  2C5Q A;  4C8P A;  1TWA A;  4M8D A;  4NGM A;  3EZA A;  3S9M A;  1W27 A;  2A6E D;  5F09 A;  1TWH A;  3SR3 A;  1J3L A;  1JDE A;  4INJ A;  1TWG A;  2LPJ A;  3TLY A;  4TJV A;  3S9L A;  4OC5 A;  1SMY D;  3I74 A;  2MP0 A;  3GJZ A;  1IW7 D;  1A9X B;  3D7F A;  1ZL0 A;  2R92 A;  4NGT A;  4C9V A;  4FBS A;  2B0A A;  3SJE A;  3T05 A;  4C8T A;  3CQZ A;  3D7H A;  1ZYM A;  3BXM A;  2MQA A;  4OC3 A;  2FM4 A;  4J0N A;  4C5R A;  3K9T A;  2OLS A;  4P4B A;  4OC4 A;  4NGQ A;  1CS0 B;  2LPI A;  1VBH A;  4CO9 A;  2F5J A;  1VI4 A;  4P44 A;  2X0S A;  2JBK A;  3T0T A;  3LR6 A;  4E94 A;  1NBW A;  2JA7 A;  2A69 D;  3EIF A;  2HRO A;  2E28 A;  4KNG E;  2EZA A;  2VK9 A;  4JVO A;  2X0P A;  2YII A;  3TLE A;  2R93 A;  1I3Q A;  3SJX A;  2A6H D;  3IIB A;  4QIW A;  2GP4 A;  2OOT A;  3LR8 A;  3ICU A;  3S9N A;  4NGN A;  1T36 B;  5ELY A;  4C9U A;  2D0O A;  1XF1 A;  5FD8 A;  1YNN D;  2MX8 A;  1KEE B;  4C86 A;  3TLG A;  4MJX A;  2EZB A;  4JZ0 A; 
#chains in the Genus database with same CATH homology
 3T0T A;  3EZE A;  3T07 A;  2MP0 A;  2HI6 A;  2FM4 A;  2R82 A;  1DIK A;  1ZYM A;  3EZA A;  1KC7 A;  2HRO A;  1EZA A;  2EZC A;  2E28 A;  2OLS A;  2EZA A;  1KBL A;  1GGO A;  1VBH A;  1VBG A;  1EZB A;  3EZB A;  1JDE A;  2EZB A;  3T05 A;  2HWG A;  2X0S A;  5JVL A;  2DIK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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