2MP0A

Protein phosphorylation upon a fleeting encounter
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
249
structure length
249
Chain Sequence
MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRAVQEQVASE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Phosphoenolpyruvate-protein phosphotransferase
publication title Visualizing an Ultra-Weak Protein-Protein Interaction in Phosphorylation Signaling
doi rcsb
source organism Escherichia coli
molecule tags Transferase
total genus 74
structure length 249
sequence length 249
ec nomenclature ec 2.7.3.9: Phosphoenolpyruvate--protein phosphotransferase.
pdb deposition date 2014-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00391 PEP-utilizers PEP-utilising enzyme, mobile domain
A PF05524 PEP-utilisers_N PEP-utilising enzyme, N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.10 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 PtsI, HPr-binding domain 2mp0A02
3.50.30.10 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Phosphohistidine domain 2mp0A01
5JVLA 2MP0A 2HROA 2DIKA 2HI6A 2E28A 2X0SA 2FM4A 1DIKA 1VBHA 1GGOA 1EZBA 2OLSA 2R82A 1VBGA 2HWGA 3T05A 1KBLA 2EZCA 3T07A 2EZBA 3EZBA 1KC7A 1ZYMA 1EZAA 3EZAA 1JDEA 3T0TA 2EZAA 3EZEA
chains in the Genus database with same CATH superfamily
4LQGA 1KEEB 2N3EA 5ELYA 2XEIA 4JVOA 4OC1A 3G23A 3FEEA 4MCPA 3D7FA 1IW7D 3EZEA 1XF1A 2FIOA 2A6ED 4IIXA 2D0PA 4V2QA 3SJEA 2C5QA 4NGNA 1V6CA 2D0OA 2O5JD 3TLAA 4MCSA 4JZ0A 5F9MA 1J3LA 3LR8A 3U1BA 3KRVA 2A68D 2E2IA 3RBUA 4CQ5A 4NGPA 4NGMA 2R82A 1VBGA 4C9UA 1TWGA 1KBLA 2EZCA 1R61A 4OC5A 2EZBA 1ZYMA 1NXJA 4J0NA 3TLGA 3T0TA 3S9MA 2YJVA 2C6PA 4C9EA 1ZRSA 3GTKA 2EK9A 2OR4A 2HI6A 4CEHA 1I50A 1GGOA 5JYBA 4NGSA 4E5SA 3TLGB 2LPIA 3BXMA 3T07A 3EZBA 3D7DA 2LPJA 3TLCA 3BI0A 4FBSA 4MI1A 3S9NA 1Y1VA 2F5JA 1TWCA 1DIKA 3FECA 2VK9A 4P4BA 3S9LA 4P4FA 3LRDA 4BABA 4C8UA 3I6SA 2YU9A 4C9RA 3GTMA 4C5SA 1VI4A 1JDBC 5F1YA 3TLBA 4COGA 4C86A 4C8PA 3IIBA 4MJXA 1NBWA 5FD8A 5K99A 1JDEA 3C8OA 4JYWA 1DE4C 2OLSA 4C8TA 2MQAA 1T6JA 5IZ2A 2DIKA 2LYIA 3SJFA 3BHXA 3SJGA 4EYSA 2LKMB 5IB9A 1K83A 4TJVA 4OC3A 4OC0A 2R93A 3ICUA 2NVYA 1ZL0A 4COBA 3IWWA 1Z8LA 3GTOA 2VUMA 3TLYA 4OMEA 2PVWA 1W27A 2MX8A 1SMYD 2AUNA 4C5UA 2B63A 2C6CA 1BXRB 2XEJA 1A9XB 2FIPA 4C8AA 1C30B 1I6VD 4P45A 1HQMD 4C2MA 3U44A 3GTLA 3EZAA 4P4DA 1CE8B 3LR6A 2CIJA 3TLEA 2E2HA 4P4IA 5F5XA 3SJXA 2OOTA 2NVXA 4P4EA 1C3OB 3FF3A 2XEGA 2N1DB 4C9VA 2EK8A 2GP4A 1Y1WA 4P44A 3GTPA 4P4JA 1SFOA 4YN3A 2Y0NA 3GTQA 3D7HA 2AQLA 2MP0A 4E94A 2YJTA 3BI1A 2YIIA 2PVVA 4V2RA 4C8CA 3GTJA 4CDJA 2B0AA 3SR3A 4CEJA 5IR2A 1M6VB 4CDKA 4KNGE 2K3NA 3NOJA 4CO9A 3VTAA 1ZYRD 2X0QA 3GTGA 2E28A 3EIFA 2K3QA 4M8DA 4C85A 1EZBA 2X0OA 2MX9A 4C9AA 2HWGA 2JBKA 4TJXA 1EZAA 4C99A 1TWHA 1Y9ZA 3T5MA 2JA6A 2LTHA 4INJA 4C6GA 1T36B 1CX8A 2JA5A 2FM4A 1VBHA 4W9YA 2XEFA 3FEDA 3LR2A 1Q5XA 4MCRA 3GJZA 4C84A 2R7ZA 3T05A 2A69D 4OC4A 4QIWA 3K4IA 3U4QA 4C8FA 4NGTA 2AUMA 2X0PA 5JVLA 1YNND 2HROA 1TWFA 1YNJD 4C5RA 1KC7A 3TLZA 3KASA 2C6GA 1T6PA 2A6HD 1I3QA 1R9TA 2R92A 1TWAA 1WVMA 4OC2A 5D29A 4TWEA 2K3OA 3D7GA 4IIYA 3H0GA 4NGRA 1Y2MA 4BAAA 1WCMA 1CS0B 4MCQA 3FKIA 2EZAA 3NZ4A 2PCNA 2CW0D 3TYXA 2JBJA 4CZ1A 2X0SA 4NGQA 3CQZA 3K9TA 2JA7A 3I74A 2BE5D 4X3RA 4CEIA 5F09A 4H1HA
chains in the Genus database with same CATH topology
5JVLA 2MP0A 2HROA 2DIKA 2HI6A 2E28A 2X0SA 2FM4A 1DIKA 1VBHA 1GGOA 1EZBA 2OLSA 2R82A 1VBGA 2HWGA 3T05A 1KBLA 2EZCA 3T07A 2EZBA 3EZBA 1KC7A 1ZYMA 1EZAA 3EZAA 1JDEA 3T0TA 2EZAA 3EZEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5JVL A;  2MP0 A;  2HRO A;  2DIK A;  2HI6 A;  2E28 A;  2X0S A;  2FM4 A;  1DIK A;  1VBH A;  1GGO A;  1EZB A;  2OLS A;  2R82 A;  1VBG A;  2HWG A;  3T05 A;  1KBL A;  2EZC A;  3T07 A;  2EZB A;  3EZB A;  1KC7 A;  1ZYM A;  1EZA A;  3EZA A;  1JDE A;  3T0T A;  2EZA A;  3EZE A; 
#chains in the Genus database with same CATH topology
 4LQG A;  1KEE B;  2N3E A;  5ELY A;  2XEI A;  4JVO A;  4OC1 A;  3G23 A;  3FEE A;  4MCP A;  3D7F A;  1IW7 D;  3EZE A;  1XF1 A;  2FIO A;  2A6E D;  4IIX A;  2D0P A;  4V2Q A;  3SJE A;  2C5Q A;  4NGN A;  1V6C A;  2D0O A;  2O5J D;  3TLA A;  4MCS A;  4JZ0 A;  5F9M A;  1J3L A;  3LR8 A;  3U1B A;  3KRV A;  2A68 D;  2E2I A;  3RBU A;  4CQ5 A;  4NGP A;  4NGM A;  2R82 A;  1VBG A;  4C9U A;  1TWG A;  1KBL A;  2EZC A;  1R61 A;  4OC5 A;  2EZB A;  1ZYM A;  1NXJ A;  4J0N A;  3TLG A;  3T0T A;  3S9M A;  2YJV A;  2C6P A;  4C9E A;  1ZRS A;  3GTK A;  2EK9 A;  2OR4 A;  2HI6 A;  4CEH A;  1I50 A;  1GGO A;  5JYB A;  4NGS A;  4E5S A;  3TLG B;  2LPI A;  3BXM A;  3T07 A;  3EZB A;  3D7D A;  2LPJ A;  3TLC A;  3BI0 A;  4FBS A;  4MI1 A;  3S9N A;  1Y1V A;  2F5J A;  1TWC A;  1DIK A;  3FEC A;  2VK9 A;  4P4B A;  3S9L A;  4P4F A;  3LRD A;  4BAB A;  4C8U A;  3I6S A;  2YU9 A;  4C9R A;  3GTM A;  4C5S A;  1VI4 A;  1JDB C;  5F1Y A;  3TLB A;  4COG A;  4C86 A;  4C8P A;  3IIB A;  4MJX A;  1NBW A;  5FD8 A;  5K99 A;  1JDE A;  3C8O A;  4JYW A;  1DE4 C;  2OLS A;  4C8T A;  2MQA A;  1T6J A;  5IZ2 A;  2DIK A;  2LYI A;  3SJF A;  3BHX A;  3SJG A;  4EYS A;  2LKM B;  5IB9 A;  1K83 A;  4TJV A;  4OC3 A;  4OC0 A;  2R93 A;  3ICU A;  2NVY A;  1ZL0 A;  4COB A;  3IWW A;  1Z8L A;  3GTO A;  2VUM A;  3TLY A;  4OME A;  2PVW A;  1W27 A;  2MX8 A;  1SMY D;  2AUN A;  4C5U A;  2B63 A;  2C6C A;  1BXR B;  2XEJ A;  1A9X B;  2FIP A;  4C8A A;  1C30 B;  1I6V D;  4P45 A;  1HQM D;  4C2M A;  3U44 A;  3GTL A;  3EZA A;  4P4D A;  1CE8 B;  3LR6 A;  2CIJ A;  3TLE A;  2E2H A;  4P4I A;  5F5X A;  3SJX A;  2OOT A;  2NVX A;  4P4E A;  1C3O B;  3FF3 A;  2XEG A;  2N1D B;  4C9V A;  2EK8 A;  2GP4 A;  1Y1W A;  4P44 A;  3GTP A;  4P4J A;  1SFO A;  4YN3 A;  2Y0N A;  3GTQ A;  3D7H A;  2AQL A;  2MP0 A;  4E94 A;  2YJT A;  3BI1 A;  2YII A;  2PVV A;  4V2R A;  4C8C A;  3GTJ A;  4CDJ A;  2B0A A;  3SR3 A;  4CEJ A;  5IR2 A;  1M6V B;  4CDK A;  4KNG E;  2K3N A;  3NOJ A;  4CO9 A;  3VTA A;  1ZYR D;  2X0Q A;  3GTG A;  2E28 A;  3EIF A;  2K3Q A;  4M8D A;  4C85 A;  1EZB A;  2X0O A;  2MX9 A;  4C9A A;  2HWG A;  2JBK A;  4TJX A;  1EZA A;  4C99 A;  1TWH A;  1Y9Z A;  3T5M A;  2JA6 A;  2LTH A;  4INJ A;  4C6G A;  1T36 B;  1CX8 A;  2JA5 A;  2FM4 A;  1VBH A;  4W9Y A;  2XEF A;  3FED A;  3LR2 A;  1Q5X A;  4MCR A;  3GJZ A;  4C84 A;  2R7Z A;  3T05 A;  2A69 D;  4OC4 A;  4QIW A;  3K4I A;  3U4Q A;  4C8F A;  4NGT A;  2AUM A;  2X0P A;  5JVL A;  1YNN D;  2HRO A;  1TWF A;  1YNJ D;  4C5R A;  1KC7 A;  3TLZ A;  3KAS A;  2C6G A;  1T6P A;  2A6H D;  1I3Q A;  1R9T A;  2R92 A;  1TWA A;  1WVM A;  4OC2 A;  5D29 A;  4TWE A;  2K3O A;  3D7G A;  4IIY A;  3H0G A;  4NGR A;  1Y2M A;  4BAA A;  1WCM A;  1CS0 B;  4MCQ A;  3FKI A;  2EZA A;  3NZ4 A;  2PCN A;  2CW0 D;  3TYX A;  2JBJ A;  4CZ1 A;  2X0S A;  4NGQ A;  3CQZ A;  3K9T A;  2JA7 A;  3I74 A;  2BE5 D;  4X3R A;  4CEI A;  5F09 A;  4H1H A; 
#chains in the Genus database with same CATH homology
 5JVL A;  2MP0 A;  2HRO A;  2DIK A;  2HI6 A;  2E28 A;  2X0S A;  2FM4 A;  1DIK A;  1VBH A;  1GGO A;  1EZB A;  2OLS A;  2R82 A;  1VBG A;  2HWG A;  3T05 A;  1KBL A;  2EZC A;  3T07 A;  2EZB A;  3EZB A;  1KC7 A;  1ZYM A;  1EZA A;  3EZA A;  1JDE A;  3T0T A;  2EZA A;  3EZE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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