2MP0A

Protein phosphorylation upon a fleeting encounter
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
249
structure length
249
Chain Sequence
MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRAVQEQVASE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Visualizing an Ultra-Weak Protein-Protein Interaction in Phosphorylation Signaling
doi rcsb
source organism Escherichia coli
molecule tags Transferase
molecule keywords Phosphoenolpyruvate-protein phosphotransferase
total genus 74
structure length 249
sequence length 249
ec nomenclature ec 2.7.3.9: Phosphoenolpyruvate--protein phosphotransferase.
pdb deposition date 2014-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00391 PEP-utilizers PEP-utilising enzyme, mobile domain
A PF05524 PEP-utilisers_N PEP-utilising enzyme, N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.10 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 PtsI, HPr-binding domain 2mp0A02
3.50.30.10 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Phosphohistidine domain 2mp0A01
2HWGA 3T05A 1EZAA 1JDEA 1VBHA 3T07A 1KBLA 3EZEA 1EZBA 1ZYMA 1VBGA 2EZBA 2EZAA 2OLSA 1KC7A 2FM4A 2DIKA 2EZCA 2E28A 2HI6A 3EZBA 2R82A 5JVLA 1GGOA 1DIKA 2MP0A 2HROA 3EZAA 2X0SA 3T0TA
chains in the Genus database with same CATH superfamily
4MCQA 4EYSA 4FBSA 1EZAA 3SJXA 2JA5A 2GP4A 3SJEA 4C9UA 3FECA 2XEIA 2XEFA 4CDJA 2K3QA 3FEDA 2LTHA 4NGNA 3U1BA 2XEGA 1ZYMA 2YJTA 1Y1WA 1C30B 2EZBA 1CX8A 4YN3A 4NGRA 4LQGA 3NZ4A 1TWHA 4MCRA 1WVMA 4C84A 3TLYA 1KC7A 4C9AA 2NVYA 3RBUA 1YNND 3LRDA 1BXRB 4C8UA 4P4IA 3SJFA 2EZCA 2D0PA 5IZ2A 3GTPA 5ELYA 4NGPA 3TLEA 3K9TA 4TJVA 3BI1A 2MQAA 4W9YA 2R93A 2C6PA 3BI0A 3H0GA 1YNJD 1ZRSA 3TYXA 2PVWA 2PCNA 1TWGA 2YJVA 5JYBA 3LR6A 1Y2MA 3VTAA 3GTJA 2EK9A 1TWCA 1M6VB 4OC1A 3T0TA 4C9EA 4QIWA 1Q5XA 4JZ0A 1CE8B 4IIYA 3BXMA 2A6ED 2R92A 3T5MA 1R9TA 1JDEA 3BHXA 4NGQA 4C5RA 3D7DA 1SFOA 4TWEA 3T07A 3TLAA 5F09A 5IB9A 2YU9A 2X0PA 3GTMA 4MCPA 3K4IA 2MX9A 4V2RA 3TLGA 4CEIA 1TWAA 2C6CA 3GTLA 2BE5D 2JA7A 4NGTA 4NGSA 2K3OA 4P4DA 4C8CA 1I6VD 4C9RA 3EIFA 4MI1A 2LPJA 4C5UA 2F5JA 2B63A 4BAAA 1C3OB 1ZL0A 2JBKA 3IIBA 4P45A 3TLZA 3IWWA 2E28A 4M8DA 3D7HA 3SR3A 3S9NA 3I74A 4NGMA 4C8FA 2JBJA 2R82A 5JVLA 1VI4A 3S9MA 1XF1A 2VUMA 3C8OA 4X3RA 2MP0A 3GJZA 2N1DB 2HROA 2LPIA 1T6JA 1IW7D 2X0QA 2JA6A 4TJXA 1Z8LA 1I50A 3LR2A 4OC2A 2XEJA 4INJA 2O5JD 2VK9A 1NBWA 4CEHA 4C8AA 2HWGA 2C5QA 3T05A 2LKMB 4OC3A 1VBHA 4JVOA 1KBLA 3EZEA 3LR8A 4P4BA 4OC4A 4E5SA 4CEJA 4KNGE 1T36B 4P4JA 2EZAA 5F5XA 5K99A 2OR4A 4C85A 2CW0D 3GTQA 2DIKA 2FM4A 4C8PA 3GTOA 3FEEA 2AQLA 3KRVA 4P4FA 3U44A 3G23A 3FKIA 1KEEB 2E2HA 5FD8A 4COGA 3EZBA 3U4QA 2C6GA 4C86A 1GGOA 1DIKA 2EK8A 2A69D 3SJGA 2N3EA 1A9XB 3TLBA 2X0OA 1Y9ZA 1R61A 2AUNA 2NVXA 4C6GA 4IIXA 4V2QA 3EZAA 3TLCA 3ICUA 4C8TA 4C99A 2R7ZA 2LYIA 1SMYD 3D7GA 4J0NA 5F1YA 2AUMA 1I3QA 4BABA 1EZBA 2A6HD 2FIOA 3S9LA 4C9VA 1ZYRD 1DE4C 2FIPA 1VBGA 1TWFA 2OOTA 3GTKA 4CZ1A 1Y1VA 2B0AA 2CIJA 3NOJA 2Y0NA 2OLSA 1J3LA 3TLGB 4JYWA 2MX8A 1K83A 1V6CA 3GTGA 4OMEA 2K3NA 4CQ5A 1CS0B 3KASA 2HI6A 4H1HA 5D29A 1T6PA 2YIIA 3CQZA 1WCMA 4MJXA 4P44A 4C2MA 1W27A 4OC5A 3FF3A 2A68D 4P4EA 5F9MA 2PVVA 4COBA 3I6SA 4CDKA 4OC0A 1HQMD 1JDBC 2D0OA 2E2IA 2X0SA 4MCSA 4E94A 5IR2A 1NXJA 3D7FA 4CO9A 4C5SA
chains in the Genus database with same CATH topology
2HWGA 3T05A 1EZAA 1JDEA 1VBHA 3T07A 1KBLA 3EZEA 1EZBA 1ZYMA 1VBGA 2EZBA 2EZAA 2OLSA 1KC7A 2FM4A 2DIKA 2EZCA 2E28A 2HI6A 3EZBA 2R82A 5JVLA 1GGOA 1DIKA 2MP0A 2HROA 3EZAA 2X0SA 3T0TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HWG A;  3T05 A;  1EZA A;  1JDE A;  1VBH A;  3T07 A;  1KBL A;  3EZE A;  1EZB A;  1ZYM A;  1VBG A;  2EZB A;  2EZA A;  2OLS A;  1KC7 A;  2FM4 A;  2DIK A;  2EZC A;  2E28 A;  2HI6 A;  3EZB A;  2R82 A;  5JVL A;  1GGO A;  1DIK A;  2MP0 A;  2HRO A;  3EZA A;  2X0S A;  3T0T A; 
#chains in the Genus database with same CATH topology
 4MCQ A;  4EYS A;  4FBS A;  1EZA A;  3SJX A;  2JA5 A;  2GP4 A;  3SJE A;  4C9U A;  3FEC A;  2XEI A;  2XEF A;  4CDJ A;  2K3Q A;  3FED A;  2LTH A;  4NGN A;  3U1B A;  2XEG A;  1ZYM A;  2YJT A;  1Y1W A;  1C30 B;  2EZB A;  1CX8 A;  4YN3 A;  4NGR A;  4LQG A;  3NZ4 A;  1TWH A;  4MCR A;  1WVM A;  4C84 A;  3TLY A;  1KC7 A;  4C9A A;  2NVY A;  3RBU A;  1YNN D;  3LRD A;  1BXR B;  4C8U A;  4P4I A;  3SJF A;  2EZC A;  2D0P A;  5IZ2 A;  3GTP A;  5ELY A;  4NGP A;  3TLE A;  3K9T A;  4TJV A;  3BI1 A;  2MQA A;  4W9Y A;  2R93 A;  2C6P A;  3BI0 A;  3H0G A;  1YNJ D;  1ZRS A;  3TYX A;  2PVW A;  2PCN A;  1TWG A;  2YJV A;  5JYB A;  3LR6 A;  1Y2M A;  3VTA A;  3GTJ A;  2EK9 A;  1TWC A;  1M6V B;  4OC1 A;  3T0T A;  4C9E A;  4QIW A;  1Q5X A;  4JZ0 A;  1CE8 B;  4IIY A;  3BXM A;  2A6E D;  2R92 A;  3T5M A;  1R9T A;  1JDE A;  3BHX A;  4NGQ A;  4C5R A;  3D7D A;  1SFO A;  4TWE A;  3T07 A;  3TLA A;  5F09 A;  5IB9 A;  2YU9 A;  2X0P A;  3GTM A;  4MCP A;  3K4I A;  2MX9 A;  4V2R A;  3TLG A;  4CEI A;  1TWA A;  2C6C A;  3GTL A;  2BE5 D;  2JA7 A;  4NGT A;  4NGS A;  2K3O A;  4P4D A;  4C8C A;  1I6V D;  4C9R A;  3EIF A;  4MI1 A;  2LPJ A;  4C5U A;  2F5J A;  2B63 A;  4BAA A;  1C3O B;  1ZL0 A;  2JBK A;  3IIB A;  4P45 A;  3TLZ A;  3IWW A;  2E28 A;  4M8D A;  3D7H A;  3SR3 A;  3S9N A;  3I74 A;  4NGM A;  4C8F A;  2JBJ A;  2R82 A;  5JVL A;  1VI4 A;  3S9M A;  1XF1 A;  2VUM A;  3C8O A;  4X3R A;  2MP0 A;  3GJZ A;  2N1D B;  2HRO A;  2LPI A;  1T6J A;  1IW7 D;  2X0Q A;  2JA6 A;  4TJX A;  1Z8L A;  1I50 A;  3LR2 A;  4OC2 A;  2XEJ A;  4INJ A;  2O5J D;  2VK9 A;  1NBW A;  4CEH A;  4C8A A;  2HWG A;  2C5Q A;  3T05 A;  2LKM B;  4OC3 A;  1VBH A;  4JVO A;  1KBL A;  3EZE A;  3LR8 A;  4P4B A;  4OC4 A;  4E5S A;  4CEJ A;  4KNG E;  1T36 B;  4P4J A;  2EZA A;  5F5X A;  5K99 A;  2OR4 A;  4C85 A;  2CW0 D;  3GTQ A;  2DIK A;  2FM4 A;  4C8P A;  3GTO A;  3FEE A;  2AQL A;  3KRV A;  4P4F A;  3U44 A;  3G23 A;  3FKI A;  1KEE B;  2E2H A;  5FD8 A;  4COG A;  3EZB A;  3U4Q A;  2C6G A;  4C86 A;  1GGO A;  1DIK A;  2EK8 A;  2A69 D;  3SJG A;  2N3E A;  1A9X B;  3TLB A;  2X0O A;  1Y9Z A;  1R61 A;  2AUN A;  2NVX A;  4C6G A;  4IIX A;  4V2Q A;  3EZA A;  3TLC A;  3ICU A;  4C8T A;  4C99 A;  2R7Z A;  2LYI A;  1SMY D;  3D7G A;  4J0N A;  5F1Y A;  2AUM A;  1I3Q A;  4BAB A;  1EZB A;  2A6H D;  2FIO A;  3S9L A;  4C9V A;  1ZYR D;  1DE4 C;  2FIP A;  1VBG A;  1TWF A;  2OOT A;  3GTK A;  4CZ1 A;  1Y1V A;  2B0A A;  2CIJ A;  3NOJ A;  2Y0N A;  2OLS A;  1J3L A;  3TLG B;  4JYW A;  2MX8 A;  1K83 A;  1V6C A;  3GTG A;  4OME A;  2K3N A;  4CQ5 A;  1CS0 B;  3KAS A;  2HI6 A;  4H1H A;  5D29 A;  1T6P A;  2YII A;  3CQZ A;  1WCM A;  4MJX A;  4P44 A;  4C2M A;  1W27 A;  4OC5 A;  3FF3 A;  2A68 D;  4P4E A;  5F9M A;  2PVV A;  4COB A;  3I6S A;  4CDK A;  4OC0 A;  1HQM D;  1JDB C;  2D0O A;  2E2I A;  2X0S A;  4MCS A;  4E94 A;  5IR2 A;  1NXJ A;  3D7F A;  4CO9 A;  4C5S A; 
#chains in the Genus database with same CATH homology
 2HWG A;  3T05 A;  1EZA A;  1JDE A;  1VBH A;  3T07 A;  1KBL A;  3EZE A;  1EZB A;  1ZYM A;  1VBG A;  2EZB A;  2EZA A;  2OLS A;  1KC7 A;  2FM4 A;  2DIK A;  2EZC A;  2E28 A;  2HI6 A;  3EZB A;  2R82 A;  5JVL A;  1GGO A;  1DIK A;  2MP0 A;  2HRO A;  3EZA A;  2X0S A;  3T0T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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