2MP0A

Protein phosphorylation upon a fleeting encounter
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
249
structure length
249
Chain Sequence
b'MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRAVQEQVASE'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Phosphoenolpyruvate-protein phosphotransferase
publication title Visualizing an Ultra-Weak Protein-Protein Interaction in Phosphorylation Signaling
doi rcsb
source organism Escherichia coli
molecule tags Transferase
total genus 74
structure length 249
sequence length 249
ec nomenclature ec 2.7.3.9: Phosphoenolpyruvate--protein phosphotransferase.
pdb deposition date 2014-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00391 PEP-utilizers PEP-utilising enzyme, mobile domain
A PF05524 PEP-utilisers_N PEP-utilising enzyme, N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.10 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 PtsI, HPr-binding domain 2mp0A02
3.50.30.10 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Phosphohistidine domain 2mp0A01
3EZBA 2E28A 3EZAA 1KC7A 1DIKA 1ZYMA 1GGOA 2HROA 2EZAA 1KBLA 1EZBA 2MP0A 2HI6A 2R82A 2FM4A 2OLSA 2DIKA 2HWGA 1VBGA 1JDEA 1VBHA 2X0SA 1EZAA 3T05A 2EZCA 2EZBA 3T0TA 3T07A 3EZEA 5JVLA
chains in the Genus database with same CATH superfamily
3EZBA 2CW0D 2OR4A 4NGNA 4C9AA 2R82A 2HI6A 5K99A 1ZRSA 2JA7A 3GTKA 1IW7D 4OC4A 2X0SA 3LRDA 1CS0B 3KASA 4CZ1A 3S9NA 4NGQA 4MCPA 3GTQA 2D0OA 2LPIA 4IIYA 4C8AA 3FKIA 2LKMB 3BHXA 3SJGA 4OC1A 3EIFA 3T5MA 1YNJD 3GJZA 3T05A 4CDJA 2JBJA 3U4QA 4JVOA 2B0AA 2D0PA 1A9XB 3D7GA 2OLSA 3TLZA 5F1YA 3FF3A 3K4IA 4CDKA 4P4DA 4C8TA 2EZCA 2AUNA 4C85A 2MQAA 1ZL0A 3TLBA 2YJVA 2EK8A 1R61A 1DIKA 1GGOA 2O5JD 4NGSA 4JZ0A 2C5QA 3TLEA 2N3EA 4H1HA 1SMYD 5F09A 3GTLA 1Y1WA 2AQLA 4P4BA 3I74A 2VUMA 4P45A 2BE5D 1I6VD 2XEJA 4C9UA 5D29A 1T6JA 3FEDA 1DE4C 4MCRA 1I50A 4E94A 3TLCA 2MX9A 4C5RA 4COBA 2EZBA 4NGTA 3T07A 3EZEA 2XEIA 2X0PA 2XEFA 4COGA 1KBLA 4OC5A 4C84A 2R7ZA 4C86A 4MCQA 2YU9A 1CX8A 3GTPA 2OOTA 3EZAA 4BABA 3TLGA 3BXMA 1Y9ZA 2EZAA 3NOJA 3U44A 4P4IA 2B63A 1C30B 4V2RA 2A6HD 2DIKA 1I3QA 4NGRA 2R93A 3LR2A 2XEGA 4NGPA 4LQGA 1TWFA 4FBSA 1C3OB 3S9MA 5ELYA 4NGMA 1BXRB 4INJA 3LR6A 4C9EA 4C5SA 1TWGA 3SJEA 4CEHA 1TWAA 1Y1VA 3CQZA 4MJXA 5JYBA 1VBGA 3K9TA 3NZ4A 4C8CA 2R92A 2N1DB 1T6PA 3S9LA 1Y2MA 4QIWA 4W9YA 3RBUA 3TYXA 2PVWA 1JDBC 2PCNA 3D7DA 2CIJA 1TWCA 3LR8A 2AUMA 2E2IA 1ZYRD 1J3LA 2YJTA 4OC2A 5F5XA 4YN3A 3G23A 4M8DA 3VTAA 3SR3A 4C8PA 1ZYMA 3GTGA 2HROA 1R9TA 1EZBA 2C6GA 2JA6A 4CEIA 2HWGA 3BI0A 1JDEA 5IR2A 2LYIA 2LTHA 2Y0NA 5F9MA 2PVVA 5IB9A 4OC3A 4C2MA 2F5JA 2FIPA 1WVMA 1W27A 2C6PA 4J0NA 3TLGB 4P4EA 2FM4A 5IZ2A 1CE8B 3I6SA 2E2HA 2K3OA 3KRVA 1WCMA 2K3NA 2JA5A 1Z8LA 3T0TA 2VK9A 2E28A 2GP4A 3GTMA 4C5UA 4OMEA 2K3QA 3FEEA 4C8FA 1TWHA 2A68D 1Q5XA 2C6CA 2LPJA 3GTOA 3D7HA 3SJXA 4P4FA 2MX8A 4CQ5A 4C9VA 2YIIA 1HQMD 1NBWA 4P4JA 5JVLA 4C99A 4JYWA 4C9RA 3FECA 3IIBA 1T36B 2JBKA 3H0GA 4C6GA 1XF1A 2NVYA 1VBHA 1EZAA 3BI1A 3C8OA 4MCSA 1M6VB 4TWEA 1YNND 4X3RA 1KC7A 4TJXA 1VI4A 2X0OA 5FD8A 3TLYA 4CO9A 1SFOA 1KEEB 4MI1A 2X0QA 4BAAA 4TJVA 4P44A 3ICUA 4V2QA 3TLAA 4C8UA 4E5SA 1V6CA 3IWWA 3D7FA 3SJFA 4IIXA 2EK9A 3U1BA 2MP0A 4CEJA 1K83A 2A6ED 3GTJA 4OC0A 2FIOA 2A69D 2NVXA 4EYSA 1NXJA 4KNGE
chains in the Genus database with same CATH topology
3EZBA 2E28A 3EZAA 1KC7A 1DIKA 1ZYMA 1GGOA 2HROA 2EZAA 1KBLA 1EZBA 2MP0A 2HI6A 2R82A 2FM4A 2OLSA 2DIKA 2HWGA 1VBGA 1JDEA 1VBHA 2X0SA 1EZAA 3T05A 2EZCA 2EZBA 3T0TA 3T07A 3EZEA 5JVLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EZB A;  2E28 A;  3EZA A;  1KC7 A;  1DIK A;  1ZYM A;  1GGO A;  2HRO A;  2EZA A;  1KBL A;  1EZB A;  2MP0 A;  2HI6 A;  2R82 A;  2FM4 A;  2OLS A;  2DIK A;  2HWG A;  1VBG A;  1JDE A;  1VBH A;  2X0S A;  1EZA A;  3T05 A;  2EZC A;  2EZB A;  3T0T A;  3T07 A;  3EZE A;  5JVL A; 
#chains in the Genus database with same CATH topology
 3EZB A;  2CW0 D;  2OR4 A;  4NGN A;  4C9A A;  2R82 A;  2HI6 A;  5K99 A;  1ZRS A;  2JA7 A;  3GTK A;  1IW7 D;  4OC4 A;  2X0S A;  3LRD A;  1CS0 B;  3KAS A;  4CZ1 A;  3S9N A;  4NGQ A;  4MCP A;  3GTQ A;  2D0O A;  2LPI A;  4IIY A;  4C8A A;  3FKI A;  2LKM B;  3BHX A;  3SJG A;  4OC1 A;  3EIF A;  3T5M A;  1YNJ D;  3GJZ A;  3T05 A;  4CDJ A;  2JBJ A;  3U4Q A;  4JVO A;  2B0A A;  2D0P A;  1A9X B;  3D7G A;  2OLS A;  3TLZ A;  5F1Y A;  3FF3 A;  3K4I A;  4CDK A;  4P4D A;  4C8T A;  2EZC A;  2AUN A;  4C85 A;  2MQA A;  1ZL0 A;  3TLB A;  2YJV A;  2EK8 A;  1R61 A;  1DIK A;  1GGO A;  2O5J D;  4NGS A;  4JZ0 A;  2C5Q A;  3TLE A;  2N3E A;  4H1H A;  1SMY D;  5F09 A;  3GTL A;  1Y1W A;  2AQL A;  4P4B A;  3I74 A;  2VUM A;  4P45 A;  2BE5 D;  1I6V D;  2XEJ A;  4C9U A;  5D29 A;  1T6J A;  3FED A;  1DE4 C;  4MCR A;  1I50 A;  4E94 A;  3TLC A;  2MX9 A;  4C5R A;  4COB A;  2EZB A;  4NGT A;  3T07 A;  3EZE A;  2XEI A;  2X0P A;  2XEF A;  4COG A;  1KBL A;  4OC5 A;  4C84 A;  2R7Z A;  4C86 A;  4MCQ A;  2YU9 A;  1CX8 A;  3GTP A;  2OOT A;  3EZA A;  4BAB A;  3TLG A;  3BXM A;  1Y9Z A;  2EZA A;  3NOJ A;  3U44 A;  4P4I A;  2B63 A;  1C30 B;  4V2R A;  2A6H D;  2DIK A;  1I3Q A;  4NGR A;  2R93 A;  3LR2 A;  2XEG A;  4NGP A;  4LQG A;  1TWF A;  4FBS A;  1C3O B;  3S9M A;  5ELY A;  4NGM A;  1BXR B;  4INJ A;  3LR6 A;  4C9E A;  4C5S A;  1TWG A;  3SJE A;  4CEH A;  1TWA A;  1Y1V A;  3CQZ A;  4MJX A;  5JYB A;  1VBG A;  3K9T A;  3NZ4 A;  4C8C A;  2R92 A;  2N1D B;  1T6P A;  3S9L A;  1Y2M A;  4QIW A;  4W9Y A;  3RBU A;  3TYX A;  2PVW A;  1JDB C;  2PCN A;  3D7D A;  2CIJ A;  1TWC A;  3LR8 A;  2AUM A;  2E2I A;  1ZYR D;  1J3L A;  2YJT A;  4OC2 A;  5F5X A;  4YN3 A;  3G23 A;  4M8D A;  3VTA A;  3SR3 A;  4C8P A;  1ZYM A;  3GTG A;  2HRO A;  1R9T A;  1EZB A;  2C6G A;  2JA6 A;  4CEI A;  2HWG A;  3BI0 A;  1JDE A;  5IR2 A;  2LYI A;  2LTH A;  2Y0N A;  5F9M A;  2PVV A;  5IB9 A;  4OC3 A;  4C2M A;  2F5J A;  2FIP A;  1WVM A;  1W27 A;  2C6P A;  4J0N A;  3TLG B;  4P4E A;  2FM4 A;  5IZ2 A;  1CE8 B;  3I6S A;  2E2H A;  2K3O A;  3KRV A;  1WCM A;  2K3N A;  2JA5 A;  1Z8L A;  3T0T A;  2VK9 A;  2E28 A;  2GP4 A;  3GTM A;  4C5U A;  4OME A;  2K3Q A;  3FEE A;  4C8F A;  1TWH A;  2A68 D;  1Q5X A;  2C6C A;  2LPJ A;  3GTO A;  3D7H A;  3SJX A;  4P4F A;  2MX8 A;  4CQ5 A;  4C9V A;  2YII A;  1HQM D;  1NBW A;  4P4J A;  5JVL A;  4C99 A;  4JYW A;  4C9R A;  3FEC A;  3IIB A;  1T36 B;  2JBK A;  3H0G A;  4C6G A;  1XF1 A;  2NVY A;  1VBH A;  1EZA A;  3BI1 A;  3C8O A;  4MCS A;  1M6V B;  4TWE A;  1YNN D;  4X3R A;  1KC7 A;  4TJX A;  1VI4 A;  2X0O A;  5FD8 A;  3TLY A;  4CO9 A;  1SFO A;  1KEE B;  4MI1 A;  2X0Q A;  4BAA A;  4TJV A;  4P44 A;  3ICU A;  4V2Q A;  3TLA A;  4C8U A;  4E5S A;  1V6C A;  3IWW A;  3D7F A;  3SJF A;  4IIX A;  2EK9 A;  3U1B A;  2MP0 A;  4CEJ A;  1K83 A;  2A6E D;  3GTJ A;  4OC0 A;  2FIO A;  2A69 D;  2NVX A;  4EYS A;  1NXJ A;  4KNG E; 
#chains in the Genus database with same CATH homology
 3EZB A;  2E28 A;  3EZA A;  1KC7 A;  1DIK A;  1ZYM A;  1GGO A;  2HRO A;  2EZA A;  1KBL A;  1EZB A;  2MP0 A;  2HI6 A;  2R82 A;  2FM4 A;  2OLS A;  2DIK A;  2HWG A;  1VBG A;  1JDE A;  1VBH A;  2X0S A;  1EZA A;  3T05 A;  2EZC A;  2EZB A;  3T0T A;  3T07 A;  3EZE A;  5JVL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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