2MP0A

Protein phosphorylation upon a fleeting encounter
Total Genus 74
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
249
structure length
249
Chain Sequence
MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRAVQEQVASE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Visualizing an Ultra-Weak Protein-Protein Interaction in Phosphorylation Signaling
doi rcsb
source organism Escherichia coli
molecule tags Transferase
molecule keywords Phosphoenolpyruvate-protein phosphotransferase
total genus 74
structure length 249
sequence length 249
ec nomenclature ec 2.7.3.9: Phosphoenolpyruvate--protein phosphotransferase.
pdb deposition date 2014-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00391 PEP-utilizers PEP-utilising enzyme, mobile domain
A PF05524 PEP-utilisers_N PEP-utilising enzyme, N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.10 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 PtsI, HPr-binding domain 2mp0A02
3.50.30.10 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Phosphohistidine domain 2mp0A01
1VBGA 3T07A 2HWGA 1EZAA 3EZAA 5JVLA 2EZBA 2X0SA 2DIKA 2MP0A 1EZBA 1DIKA 3EZEA 1ZYMA 1JDEA 3T0TA 2R82A 2E28A 3EZBA 2FM4A 1KBLA 2HI6A 1VBHA 2HROA 1GGOA 2OLSA 3T05A 1KC7A 2EZAA 2EZCA
chains in the Genus database with same CATH superfamily
2K3QA 1TWFA 3H0GA 2C6GA 3SR3A 1VBGA 2B63A 2O5JD 3FF3A 4CEIA 3IIBA 2E2HA 3SJXA 3TLGB 1M6VB 3U1BA 2C5QA 4OC1A 4COGA 4KNGE 3S9LA 1EZAA 3BHXA 2A6ED 4CEHA 4MCRA 4TJVA 4TJXA 2R93A 3TLYA 1I3QA 2LPIA 4V2QA 3RBUA 3GTQA 2NVYA 3TLZA 2YIIA 1CX8A 4NGTA 4C86A 2C6PA 2R82A 1T6PA 2A6HD 5F9MA 4CZ1A 1J3LA 2C6CA 4MJXA 4C85A 4COBA 2YU9A 2OLSA 1ZYRD 4P4IA 2K3NA 4C5UA 2FIOA 3TLEA 4C8FA 4CEJA 1KEEB 4X3RA 4E94A 2PVWA 1W27A 1GGOA 4C8PA 2BE5D 2X0PA 5F5XA 1KC7A 4C84A 1JDBC 4C9RA 2LYIA 1I6VD 3LR6A 3GTJA 4C5RA 2MQAA 4C8CA 5JYBA 4OC0A 4P44A 1IW7D 1TWHA 3T5MA 3C8OA 3TYXA 2JA5A 2B0AA 4BABA 2JA7A 5JVLA 2GP4A 2F5JA 2MX8A 4P45A 2X0OA 1DIKA 3EZEA 1SFOA 4JZ0A 3D7GA 4NGSA 1YNJD 3GTGA 4JYWA 2A69D 3ICUA 4C9VA 3LRDA 1T6JA 3IWWA 2FIPA 3EZBA 3S9NA 1WCMA 3FECA 2FM4A 3LR8A 3FEEA 4CQ5A 5IB9A 2YJTA 3BI0A 4C9AA 4E5SA 3GTMA 1WVMA 3U4QA 2XEIA 2NVXA 3KRVA 4OC4A 5IZ2A 4P4JA 1TWCA 4P4FA 5K99A 2K3OA 2LPJA 2EZCA 1DE4C 2AUMA 4P4BA 2AUNA 3K9TA 2R92A 1HQMD 2YJVA 3KASA 4OC3A 3GTPA 2Y0NA 4M8DA 2OOTA 3LR2A 4EYSA 3BI1A 3GTOA 1TWAA 3T07A 5F09A 2HWGA 4JVOA 4V2RA 2LTHA 1VI4A 3G23A 2X0SA 4CDKA 1Y2MA 4TWEA 2N1DB 3SJGA 1EZBA 1CS0B 1K83A 1TWGA 1BXRB 1JDEA 2CIJA 3NOJA 3T0TA 1Y1WA 1C3OB 4P4DA 2E28A 1R9TA 4NGPA 4C2MA 3TLBA 2X0QA 4IIYA 1NBWA 1KBLA 5ELYA 4W9YA 5F1YA 2HROA 4C5SA 2MX9A 3I74A 4IIXA 1Y9ZA 3D7FA 4NGRA 2EK8A 4NGMA 2JA6A 4MCQA 4C8UA 2VK9A 5IR2A 3T05A 2N3EA 5D29A 2CW0D 4C9EA 3SJEA 2PCNA 4NGQA 4C8AA 3GJZA 3S9MA 4CO9A 2R7ZA 1CE8B 4INJA 4MI1A 1A9XB 4QIWA 3FEDA 3GTLA 2EK9A 3GTKA 5FD8A 2XEJA 4YN3A 1I50A 1C30B 3EIFA 4FBSA 3I6SA 4NGNA 3TLAA 3NZ4A 4C99A 3EZAA 1NXJA 2EZBA 4C6GA 2A68D 1ZRSA 1Z8LA 1ZL0A 4OMEA 3SJFA 2DIKA 2VUMA 2MP0A 3FKIA 1T36B 1XF1A 4LQGA 2XEGA 3D7HA 4H1HA 1ZYMA 3K4IA 3U44A 2E2IA 2OR4A 1YNND 2D0OA 3BXMA 2JBJA 2D0PA 2XEFA 4P4EA 1V6CA 1R61A 3VTAA 2LKMB 4MCSA 4OC5A 3TLGA 4C9UA 4MCPA 3TLCA 3CQZA 2HI6A 1VBHA 4J0NA 1SMYD 1Y1VA 4OC2A 2JBKA 1Q5XA 2PVVA 4CDJA 2AQLA 2EZAA 4BAAA 4C8TA 3D7DA
chains in the Genus database with same CATH topology
1VBGA 3T07A 2HWGA 1EZAA 3EZAA 5JVLA 2EZBA 2X0SA 2DIKA 2MP0A 1EZBA 1DIKA 3EZEA 1ZYMA 1JDEA 3T0TA 2R82A 2E28A 3EZBA 2FM4A 1KBLA 2HI6A 1VBHA 2HROA 1GGOA 2OLSA 3T05A 1KC7A 2EZAA 2EZCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VBG A;  3T07 A;  2HWG A;  1EZA A;  3EZA A;  5JVL A;  2EZB A;  2X0S A;  2DIK A;  2MP0 A;  1EZB A;  1DIK A;  3EZE A;  1ZYM A;  1JDE A;  3T0T A;  2R82 A;  2E28 A;  3EZB A;  2FM4 A;  1KBL A;  2HI6 A;  1VBH A;  2HRO A;  1GGO A;  2OLS A;  3T05 A;  1KC7 A;  2EZA A;  2EZC A; 
#chains in the Genus database with same CATH topology
 2K3Q A;  1TWF A;  3H0G A;  2C6G A;  3SR3 A;  1VBG A;  2B63 A;  2O5J D;  3FF3 A;  4CEI A;  3IIB A;  2E2H A;  3SJX A;  3TLG B;  1M6V B;  3U1B A;  2C5Q A;  4OC1 A;  4COG A;  4KNG E;  3S9L A;  1EZA A;  3BHX A;  2A6E D;  4CEH A;  4MCR A;  4TJV A;  4TJX A;  2R93 A;  3TLY A;  1I3Q A;  2LPI A;  4V2Q A;  3RBU A;  3GTQ A;  2NVY A;  3TLZ A;  2YII A;  1CX8 A;  4NGT A;  4C86 A;  2C6P A;  2R82 A;  1T6P A;  2A6H D;  5F9M A;  4CZ1 A;  1J3L A;  2C6C A;  4MJX A;  4C85 A;  4COB A;  2YU9 A;  2OLS A;  1ZYR D;  4P4I A;  2K3N A;  4C5U A;  2FIO A;  3TLE A;  4C8F A;  4CEJ A;  1KEE B;  4X3R A;  4E94 A;  2PVW A;  1W27 A;  1GGO A;  4C8P A;  2BE5 D;  2X0P A;  5F5X A;  1KC7 A;  4C84 A;  1JDB C;  4C9R A;  2LYI A;  1I6V D;  3LR6 A;  3GTJ A;  4C5R A;  2MQA A;  4C8C A;  5JYB A;  4OC0 A;  4P44 A;  1IW7 D;  1TWH A;  3T5M A;  3C8O A;  3TYX A;  2JA5 A;  2B0A A;  4BAB A;  2JA7 A;  5JVL A;  2GP4 A;  2F5J A;  2MX8 A;  4P45 A;  2X0O A;  1DIK A;  3EZE A;  1SFO A;  4JZ0 A;  3D7G A;  4NGS A;  1YNJ D;  3GTG A;  4JYW A;  2A69 D;  3ICU A;  4C9V A;  3LRD A;  1T6J A;  3IWW A;  2FIP A;  3EZB A;  3S9N A;  1WCM A;  3FEC A;  2FM4 A;  3LR8 A;  3FEE A;  4CQ5 A;  5IB9 A;  2YJT A;  3BI0 A;  4C9A A;  4E5S A;  3GTM A;  1WVM A;  3U4Q A;  2XEI A;  2NVX A;  3KRV A;  4OC4 A;  5IZ2 A;  4P4J A;  1TWC A;  4P4F A;  5K99 A;  2K3O A;  2LPJ A;  2EZC A;  1DE4 C;  2AUM A;  4P4B A;  2AUN A;  3K9T A;  2R92 A;  1HQM D;  2YJV A;  3KAS A;  4OC3 A;  3GTP A;  2Y0N A;  4M8D A;  2OOT A;  3LR2 A;  4EYS A;  3BI1 A;  3GTO A;  1TWA A;  3T07 A;  5F09 A;  2HWG A;  4JVO A;  4V2R A;  2LTH A;  1VI4 A;  3G23 A;  2X0S A;  4CDK A;  1Y2M A;  4TWE A;  2N1D B;  3SJG A;  1EZB A;  1CS0 B;  1K83 A;  1TWG A;  1BXR B;  1JDE A;  2CIJ A;  3NOJ A;  3T0T A;  1Y1W A;  1C3O B;  4P4D A;  2E28 A;  1R9T A;  4NGP A;  4C2M A;  3TLB A;  2X0Q A;  4IIY A;  1NBW A;  1KBL A;  5ELY A;  4W9Y A;  5F1Y A;  2HRO A;  4C5S A;  2MX9 A;  3I74 A;  4IIX A;  1Y9Z A;  3D7F A;  4NGR A;  2EK8 A;  4NGM A;  2JA6 A;  4MCQ A;  4C8U A;  2VK9 A;  5IR2 A;  3T05 A;  2N3E A;  5D29 A;  2CW0 D;  4C9E A;  3SJE A;  2PCN A;  4NGQ A;  4C8A A;  3GJZ A;  3S9M A;  4CO9 A;  2R7Z A;  1CE8 B;  4INJ A;  4MI1 A;  1A9X B;  4QIW A;  3FED A;  3GTL A;  2EK9 A;  3GTK A;  5FD8 A;  2XEJ A;  4YN3 A;  1I50 A;  1C30 B;  3EIF A;  4FBS A;  3I6S A;  4NGN A;  3TLA A;  3NZ4 A;  4C99 A;  3EZA A;  1NXJ A;  2EZB A;  4C6G A;  2A68 D;  1ZRS A;  1Z8L A;  1ZL0 A;  4OME A;  3SJF A;  2DIK A;  2VUM A;  2MP0 A;  3FKI A;  1T36 B;  1XF1 A;  4LQG A;  2XEG A;  3D7H A;  4H1H A;  1ZYM A;  3K4I A;  3U44 A;  2E2I A;  2OR4 A;  1YNN D;  2D0O A;  3BXM A;  2JBJ A;  2D0P A;  2XEF A;  4P4E A;  1V6C A;  1R61 A;  3VTA A;  2LKM B;  4MCS A;  4OC5 A;  3TLG A;  4C9U A;  4MCP A;  3TLC A;  3CQZ A;  2HI6 A;  1VBH A;  4J0N A;  1SMY D;  1Y1V A;  4OC2 A;  2JBK A;  1Q5X A;  2PVV A;  4CDJ A;  2AQL A;  2EZA A;  4BAA A;  4C8T A;  3D7D A; 
#chains in the Genus database with same CATH homology
 1VBG A;  3T07 A;  2HWG A;  1EZA A;  3EZA A;  5JVL A;  2EZB A;  2X0S A;  2DIK A;  2MP0 A;  1EZB A;  1DIK A;  3EZE A;  1ZYM A;  1JDE A;  3T0T A;  2R82 A;  2E28 A;  3EZB A;  2FM4 A;  1KBL A;  2HI6 A;  1VBH A;  2HRO A;  1GGO A;  2OLS A;  3T05 A;  1KC7 A;  2EZA A;  2EZC A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...