The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
98
|
sequence length |
336
|
structure length |
309
|
Chain Sequence |
PSRTELLAEEYLRREPQKFRLARIARLAVPPAYQDVYVSPDAENELQAFGRDAAGRLQYRYHPDFVQAGALKKWQRLTRFAGALPTLKVATTADLRASGLPPRKVMALMTRLLHVARFRVTYGLSTLRQRHVVVDGNTVTFRFKGKHGVSQHKATSDRTLAANMQKLLDLPGPWLFQTVDAGGGERRRIHSTELNAYLREVIGPFTAKDFRTWGGTLLAAEYLAQQGTESSERQAKKVLVDCVKFVADDLGNTPAVTRGSYICPVIFDRYLDGKVLDDYEPRTERQEAELEGLTRSEGALKRMLESERT
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Crystal structure of a bacterial type IB DNA topoisomerase reveals a preassembled active site in the absence of DNA.
pubmed doi rcsb |
| molecule tags |
Isomerase
|
| source organism |
Deinococcus radiodurans
|
| molecule keywords |
type I topoisomerase, putative
|
| total genus |
98
|
| structure length |
309
|
| sequence length |
336
|
| ec nomenclature | |
| pdb deposition date | 2005-11-23 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF01028 | Topoisom_I | Eukaryotic DNA topoisomerase I, catalytic core |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Orthogonal Bundle | Topoisomerase I; Chain A, domain 4 | Topoisomerase I; Chain A, domain 4 | ||
| Alpha Beta | 2-Layer Sandwich | Viral Topoisomerase I | DNA topoisomerase I domain | ||
| Alpha Beta | Alpha-Beta Complex | Topoisomerase I; Chain A, domain 3 | Topoisomerase I; Chain A, domain 3 |
#chains in the Genus database with same CATH superfamily 2H7G X; 1VCC A; 2H7F X; 1NH3 A; 1T8I A; 1RR8 C; 3M4A A; 1A41 A; 1A31 A; 1SC7 A; 1A36 A; 1SEU A; 1K4T A; 1A35 A; 1EJ9 A; 1K4S A; 1TL8 A; 1R49 A; 2F4Q A; 3IGC A; 1RRJ A; 2B9S A; 1LPQ A; #chains in the Genus database with same CATH topology 1DD5 A; 2H7G X; 2PMZ A; 3DU6 A; 3WVO A; 1NH3 A; 2BE5 D; 1A36 A; 3GTQ A; 5C9H A; 2YU9 A; 3GTP A; 1V9M A; 4QIW A; 4FGU A; 1EH1 A; 4C2M A; 4D3Y A; 1I6V D; 3K5L A; 3MAQ A; 1K83 A; 2F4Q A; 3IGC A; 4GFQ A; 4NOK A; 3K5N A; 1TWG A; 4OYD B; 1I3Q A; 1IS1 A; 1I50 A; 1RRJ A; 2JA5 A; 1YNJ D; 2A6H D; 4IP9 A; 1Y69 8; 3K58 A; 3GTL A; 4L8I A; 1VCC A; 1IW7 D; 2H7F X; 3GTG A; 4D3Z A; 3DU5 A; 3M4A A; 1T8I A; 1RR8 C; 3H0G A; 4FYD A; 3IAY A; 3CQZ A; 4EJ3 A; 1HQM D; 2CW0 D; 1A35 A; 3LHP S; 1EJ9 A; 1TL8 A; 4JLR C; 4F3E A; 3GTJ A; 3K5M A; 4FXD A; 3GTK A; 1ISE A; 1WQF A; 2E2H A; 2R7Z A; 2Y0S A; 1EK8 A; 3FKI A; 4KC6 A; 5MLC 9; 4Q5V A; 4NOL A; 2R92 A; 4Q5G A; 3K5O A; 1A41 A; 3GTM A; 1GE9 A; 2A69 D; 2A68 D; 4NOM A; 1TWH A; 1SEU A; 2O5J D; 1K4T A; 4O26 A; 1K4S A; 1TWC A; 1R49 A; 3HKZ A; 2B9S B; 1WCM A; 4AHC A; 1WQG A; 1TWA A; 2NVY A; 3P9A A; 3KYL A; 4IP8 A; 2WAQ A; 3LF9 A; 2R93 A; 4H3T A; 1TWF A; 2B9S A; 1Y1W A; 4KB4 A; 2NVX A; 1LPQ A; 4KAW X; 5JSB B; 4AYB A; 4AN8 A; 5JSN B; 1R9T A; 1A31 A; 3K59 A; 1SFO A; 1SC7 A; 2WB1 A; 1Q8I A; 3K57 A; 2JA6 A; 3GTO A; 5CQG A; 1YNN D; 1TGO A; 1ZYR D; 1R5Z A; 4LMO A; 1SMY D; 2R4G A; 4KB2 A; 4QCL A; 2E2I A; 1WQH A; 2B63 A; 1MIU A; 2A6E D; 2VUM A; 4KDD A; 2JA7 A; 3SJR A; 1Y1V A; #chains in the Genus database with same CATH homology 1DD5 A; 2H7G X; 2PMZ A; 3DU6 A; 3WVO A; 1NH3 A; 2BE5 D; 1A36 A; 3GTQ A; 5C9H A; 2YU9 A; 3GTP A; 1V9M A; 4QIW A; 4FGU A; 1EH1 A; 4C2M A; 4D3Y A; 1I6V D; 3K5L A; 3MAQ A; 1K83 A; 2F4Q A; 3IGC A; 4GFQ A; 4NOK A; 3K5N A; 1TWG A; 4OYD B; 1I3Q A; 1IS1 A; 1I50 A; 1RRJ A; 2JA5 A; 1YNJ D; 2A6H D; 4IP9 A; 1Y69 8; 3K58 A; 3GTL A; 4L8I A; 1VCC A; 1IW7 D; 2H7F X; 3GTG A; 4D3Z A; 3DU5 A; 3M4A A; 1T8I A; 1RR8 C; 3H0G A; 4FYD A; 3IAY A; 3CQZ A; 4EJ3 A; 1HQM D; 2CW0 D; 1A35 A; 3LHP S; 1EJ9 A; 1TL8 A; 4JLR C; 4F3E A; 3GTJ A; 3K5M A; 4FXD A; 3GTK A; 1ISE A; 1WQF A; 2E2H A; 2R7Z A; 2Y0S A; 1EK8 A; 3FKI A; 4KC6 A; 5MLC 9; 4Q5V A; 4NOL A; 2R92 A; 4Q5G A; 3K5O A; 1A41 A; 3GTM A; 1GE9 A; 2A69 D; 2A68 D; 4NOM A; 1TWH A; 1SEU A; 2O5J D; 1K4T A; 4O26 A; 1K4S A; 1TWC A; 1R49 A; 3HKZ A; 2B9S B; 1WCM A; 4AHC A; 1WQG A; 1TWA A; 2NVY A; 3P9A A; 3KYL A; 4IP8 A; 2WAQ A; 3LF9 A; 2R93 A; 4H3T A; 1TWF A; 2B9S A; 1Y1W A; 4KB4 A; 2NVX A; 1LPQ A; 4KAW X; 5JSB B; 4AYB A; 4AN8 A; 5JSN B; 1R9T A; 1A31 A; 3K59 A; 1SFO A; 1SC7 A; 2WB1 A; 1Q8I A; 3K57 A; 2JA6 A; 3GTO A; 5CQG A; 1YNN D; 1TGO A; 1ZYR D; 1R5Z A; 4LMO A; 1SMY D; 2R4G A; 4KB2 A; 4QCL A; 2E2I A; 1WQH A; 2B63 A; 1MIU A; 2A6E D; 2VUM A; 4KDD A; 2JA7 A; 3SJR A; 1Y1V A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
