2LPIA

Nmr structure of a monomeric mutant (a72r) of major ampullate spidroin 1 n-terminal domain
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
137
structure length
137
Chain Sequence
GSGNSHTTPWTNPGLAENFMNSFMQGLSSMPGFTASQLDDMSTIAQSMVQSIQSLAAQGRTSPNKLQALNMRFASSMAEIAASEEGGGSLSTKTSSIASAMSNAFLQTTGVVNQPFINEITQLVSMFAQAGMNDVSA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title pH-Dependent Dimerization of Spider Silk N-Terminal Domain Requires Relocation of a Wedged Tryptophan Side Chain.
pubmed doi rcsb
molecule tags Structural protein
source organism Euprosthenops australis
molecule keywords Major ampullate spidroin 1
total genus 48
structure length 137
sequence length 137
ec nomenclature
pdb deposition date 2012-02-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF16763 Spidroin_N Major ampullate spidroin 1, spider silk protein 1, N-term
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.70 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 Enzyme I; Chain A, domain 2 2lpiA01
2LPJA 2MX8A 3LRDA 3LR2A 3LR6A 2LPIA 2N3EA 4FBSA 5IZ2A 3LR8A 2K3QA 2MX9A 2LTHA
chains in the Genus database with same CATH superfamily
2E2HA 2MX8A 2F5JA 1SMYD 2HROA 2Y0NA 2N3EA 2LKMB 2MP0A 1I3QA 1EZBA 4C5SA 1SFOA 2VK9A 1TWHA 3EZEA 3LR8A 2VUMA 1YNND 2JA6A 2MQAA 3FKIA 2O5JD 4FBSA 1R9TA 1ZYMA 2JA7A 3CQZA 2A69D 2EZCA 4C2MA 4V2RA 4BABA 1I50A 4CEIA 2A68D 2CW0D 3NZ4A 4CEJA 2K3OA 1T6PA 2A6ED 4C5UA 3U44A 4CEHA 1TWAA 3H0GA 2FIPA 2NVYA 5IZ2A 4C5RA 2E2IA 1EZAA 1I6VD 2LYIA 3EZAA 1YNJD 2N1DB 4BAAA 1W27A 2JA5A 2LPIA 2EZBA 1HQMD 4QIWA 3GTPA 2R92A 2X0PA 3LR6A 1TWCA 3GTGA 2LPJA 2AQLA 3U4QA 1WCMA 4CQ5A 1Y1WA 1T6JA 2X0OA 1ZYRD 1TWGA 1K83A 2HWGA 3EZBA 2BE5D 3GTLA 2R93A 2K3NA 2YIIA 2EZAA 1IW7D 4C6GA 3GTOA 2B63A 2R7ZA 1Y2MA 2MX9A 3GTMA 2YU9A 3LRDA 3GTKA 3GTJA 3GTQA 1Y1VA 2LTHA 2A6HD 3LR2A 1TWFA 2NVXA 2K3QA 2X0QA 4V2QA 2FIOA
chains in the Genus database with same CATH topology
2E2HA 2MX8A 2F5JA 1SMYD 2Y0NA 2N3EA 2LKMB 1I3QA 1SFOA 2VK9A 1TWHA 3LR8A 2VUMA 1YNND 2JA6A 2MQAA 3FKIA 2O5JD 4FBSA 1R9TA 2JA7A 3CQZA 2A69D 4C2MA 1I50A 4CEIA 2A68D 2CW0D 4CEJA 2K3OA 2A6ED 3U44A 4CEHA 1TWAA 3H0GA 2FIPA 2NVYA 5IZ2A 2E2IA 1I6VD 2LYIA 1YNJD 2N1DB 2JA5A 2LPIA 1HQMD 4QIWA 3GTPA 2R92A 2X0PA 3LR6A 1TWCA 3GTGA 2LPJA 2AQLA 3U4QA 1WCMA 1Y1WA 2X0OA 1ZYRD 1TWGA 1K83A 2BE5D 3GTLA 2R93A 2K3NA 1IW7D 3GTOA 2B63A 2R7ZA 2MX9A 3GTMA 2YU9A 3LRDA 3GTKA 3GTJA 3GTQA 1Y1VA 2LTHA 2A6HD 3LR2A 1TWFA 2NVXA 2K3QA 2X0QA 2FIOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LPJ A;  2MX8 A;  3LRD A;  3LR2 A;  3LR6 A;  2LPI A;  2N3E A;  4FBS A;  5IZ2 A;  3LR8 A;  2K3Q A;  2MX9 A;  2LTH A; 
#chains in the Genus database with same CATH topology
 2E2H A;  2MX8 A;  2F5J A;  1SMY D;  2HRO A;  2Y0N A;  2N3E A;  2LKM B;  2MP0 A;  1I3Q A;  1EZB A;  4C5S A;  1SFO A;  2VK9 A;  1TWH A;  3EZE A;  3LR8 A;  2VUM A;  1YNN D;  2JA6 A;  2MQA A;  3FKI A;  2O5J D;  4FBS A;  1R9T A;  1ZYM A;  2JA7 A;  3CQZ A;  2A69 D;  2EZC A;  4C2M A;  4V2R A;  4BAB A;  1I50 A;  4CEI A;  2A68 D;  2CW0 D;  3NZ4 A;  4CEJ A;  2K3O A;  1T6P A;  2A6E D;  4C5U A;  3U44 A;  4CEH A;  1TWA A;  3H0G A;  2FIP A;  2NVY A;  5IZ2 A;  4C5R A;  2E2I A;  1EZA A;  1I6V D;  2LYI A;  3EZA A;  1YNJ D;  2N1D B;  4BAA A;  1W27 A;  2JA5 A;  2LPI A;  2EZB A;  1HQM D;  4QIW A;  3GTP A;  2R92 A;  2X0P A;  3LR6 A;  1TWC A;  3GTG A;  2LPJ A;  2AQL A;  3U4Q A;  1WCM A;  4CQ5 A;  1Y1W A;  1T6J A;  2X0O A;  1ZYR D;  1TWG A;  1K83 A;  2HWG A;  3EZB A;  2BE5 D;  3GTL A;  2R93 A;  2K3N A;  2YII A;  2EZA A;  1IW7 D;  4C6G A;  3GTO A;  2B63 A;  2R7Z A;  1Y2M A;  2MX9 A;  3GTM A;  2YU9 A;  3LRD A;  3GTK A;  3GTJ A;  3GTQ A;  1Y1V A;  2LTH A;  2A6H D;  3LR2 A;  1TWF A;  2NVX A;  2K3Q A;  2X0Q A;  4V2Q A;  2FIO A; 
#chains in the Genus database with same CATH homology
 2E2H A;  2MX8 A;  2F5J A;  1SMY D;  2Y0N A;  2N3E A;  2LKM B;  1I3Q A;  1SFO A;  2VK9 A;  1TWH A;  3LR8 A;  2VUM A;  1YNN D;  2JA6 A;  2MQA A;  3FKI A;  2O5J D;  4FBS A;  1R9T A;  2JA7 A;  3CQZ A;  2A69 D;  4C2M A;  1I50 A;  4CEI A;  2A68 D;  2CW0 D;  4CEJ A;  2K3O A;  2A6E D;  3U44 A;  4CEH A;  1TWA A;  3H0G A;  2FIP A;  2NVY A;  5IZ2 A;  2E2I A;  1I6V D;  2LYI A;  1YNJ D;  2N1D B;  2JA5 A;  2LPI A;  1HQM D;  4QIW A;  3GTP A;  2R92 A;  2X0P A;  3LR6 A;  1TWC A;  3GTG A;  2LPJ A;  2AQL A;  3U4Q A;  1WCM A;  1Y1W A;  2X0O A;  1ZYR D;  1TWG A;  1K83 A;  2BE5 D;  3GTL A;  2R93 A;  2K3N A;  1IW7 D;  3GTO A;  2B63 A;  2R7Z A;  2MX9 A;  3GTM A;  2YU9 A;  3LRD A;  3GTK A;  3GTJ A;  3GTQ A;  1Y1V A;  2LTH A;  2A6H D;  3LR2 A;  1TWF A;  2NVX A;  2K3Q A;  2X0Q A;  2FIO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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