2XDIA

Tryptophan repressor with l75f mutation in its apo form (no l- tryptophan bound)
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
105
structure length
105
Chain Sequence
QSPYSAAMAEQRHQEWLRFVDLLKNAYQNDLHLPLLNLMLTPDEREALGTRVRIVEELLRGEMSQRELKNEFGAGIATITRGSNSLKAAPVELRQWLEEVLLKSD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription
source organism Escherichia coli
publication title Three-Dimensional Solution NMR Structure of Apo-L75F-Trpr, a Temperature-Sensitive Mutant of the Tryptophan Repressor Protein.
pubmed doi rcsb
molecule keywords TRP OPERON REPRESSOR
total genus 22
structure length 105
sequence length 105
chains with identical sequence B
ec nomenclature
pdb deposition date 2010-05-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01371 Trp_repressor Trp repressor protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.10 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A TrpR-like 2xdiA00
2XDIA 1WRTR 1TROA 3FRWA 1WRPR 3WRPA 3SSXN 1JHGA 1ZT9A 3KORA 1RCSA 3SSWN 1TRRA 1MI7R 3G1CA 1CO0A 2OZ9R 1WRSR
chains in the Genus database with same CATH superfamily
2XDIA 4YQ9A 4YQDA 1UAMA 3KNUA 4YQ3A 4YQ1A 4YVGA 4YVIA 4YVJA 3G1CA 4YQ2A 4YPXA 1CO0A 4YQGA 4YQ6A 4H3ZA 3WRPA 4YVKA 1UALA 3FRWA 4YVHA 4YPZA 4YQ8A 4H3YA 1TROA 3KORA 4YPYA 4YQ7A 3KY7A 4YQLA 4YQ5A 1RCSA 4YQPA 1WRSR 1WRTR 4YQBA 3SSXN 4YQRA 1JHGA 4YQCA 1ZT9A 4YQ0A 4YQTA 4MCDA 1TRRA 1OY5A 4YQSA 4YQOA 1UAKA 1MI7R 4IG6A 4MCCA 4YQNA 4MCBA 1UAJA 1WRPR 4YQJA 4YQ4A 3AXZA 4YQKA 3SSWN 3QUVA 4YQQA 4YQIA 4YQAA 4YPWA 3IEFA 1P9PA 2OZ9R 5D9FA
chains in the Genus database with same CATH topology
2XDIA 1WRTR 1TROA 3FRWA 1WRPR 3WRPA 3SSXN 1JHGA 1ZT9A 3KORA 1RCSA 3SSWN 1TRRA 1MI7R 3G1CA 1CO0A 2OZ9R 1WRSR
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XDI A;  1WRT R;  1TRO A;  3FRW A;  1WRP R;  3WRP A;  3SSX N;  1JHG A;  1ZT9 A;  3KOR A;  1RCS A;  3SSW N;  1TRR A;  1MI7 R;  3G1C A;  1CO0 A;  2OZ9 R;  1WRS R; 
#chains in the Genus database with same CATH topology
 2XDI A;  4YQ9 A;  4YQD A;  1UAM A;  3KNU A;  4YQ3 A;  4YQ1 A;  4YVG A;  4YVI A;  4YVJ A;  3G1C A;  4YQ2 A;  4YPX A;  1CO0 A;  4YQG A;  4YQ6 A;  4H3Z A;  3WRP A;  4YVK A;  1UAL A;  3FRW A;  4YVH A;  4YPZ A;  4YQ8 A;  4H3Y A;  1TRO A;  3KOR A;  4YPY A;  4YQ7 A;  3KY7 A;  4YQL A;  4YQ5 A;  1RCS A;  4YQP A;  1WRS R;  1WRT R;  4YQB A;  3SSX N;  4YQR A;  1JHG A;  4YQC A;  1ZT9 A;  4YQ0 A;  4YQT A;  4MCD A;  1TRR A;  1OY5 A;  4YQS A;  4YQO A;  1UAK A;  1MI7 R;  4IG6 A;  4MCC A;  4YQN A;  4MCB A;  1UAJ A;  1WRP R;  4YQJ A;  4YQ4 A;  3AXZ A;  4YQK A;  3SSW N;  3QUV A;  4YQQ A;  4YQI A;  4YQA A;  4YPW A;  3IEF A;  1P9P A;  2OZ9 R;  5D9F A; 
#chains in the Genus database with same CATH homology
 2XDI A;  1WRT R;  1TRO A;  3FRW A;  1WRP R;  3WRP A;  3SSX N;  1JHG A;  1ZT9 A;  3KOR A;  1RCS A;  3SSW N;  1TRR A;  1MI7 R;  3G1C A;  1CO0 A;  2OZ9 R;  1WRS R; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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