4YQIA

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
249
structure length
238
Chain Sequence
GSHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGDGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
total genus 71
structure length 238
sequence length 249
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yqiA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yqiA01
4YQ8A 4YQCA 4YQTA 4YQLA 4MCBA 4IG6A 4YQKA 3IEFA 4PZKA 4H3YA 1P9PA 5GMCA 4YPXA 1IPAA 1TO0A 3NK6A 4JALA 3BBDA 4YVGA 4JAKA 1V2XA 3O7BA 4YQOA 4YVKA 4YQ0A 4MCDA 3GYQA 3BBEA 5GM8A 4YVIA 3OIIA 2EGWA 4YQRA 1O6DA 1VH0A 3N4JA 3KW2A 4KGNA 4L69A 2I6DA 3N4KA 4YPZA 4KDZA 5FAIA 1VHYA 1X7OA 3KNUA 4YQJA 4YQ9A 4YQ3A 4YVHA 4X3MA 3QUVA 5GMBA 4E8BA 4YQBA 1UALA 2V3JA 3L8UA 4YQGA 4CNEA 3E5YA 1NS5A 4CNDA 1UAMA 3OINA 4YQ2A 2Z0YA 4FAKA 1ZJRA 4YPYA 4J3CA 1J85A 1UAKA 3KTYA 3ONPA 4YQDA 1X7PA 4RG1A 4CNFA 3NK7A 5D9FA 4X3LA 3IC6A 4H3ZA 1Z85A 4YQ1A 1NXZA 4YQIA 4YQ5A 1K3RA 4YQPA 3AI9X 4YQ6A 3KY7A 4YQNA 1VHKA 1GZ0A 2QWVA 2CX8A 3BBHA 4YQ4A 5CO4A 4XBOA 2EGVA 4YQSA 3DCMX 3OIJA 3ILKA 2O3AA 1MXIA 2HA8A 2V3KA 4CNGA 3AIAA 4YQ7A 4YQAA 1UAJA 4YVJA 1V6ZA 3AXZA 2QMMA 2YY8A 4MCCA 1OY5A 4YPWA 4YQQA
chains in the Genus database with same CATH superfamily
4YQ8A 4YQCA 4YQTA 4YQLA 4MCBA 4IG6A 4YQKA 3IEFA 4FMWA 4H3YA 4PZKA 1P9PA 5GMCA 4YPXA 1IPAA 1TO0A 3NK6A 4JALA 3BBDA 1RCSA 4YVGA 4JAKA 1V2XA 3O7BA 4YQOA 4YVKA 4YQ0A 4MCDA 3GYQA 3BBEA 5GM8A 1JHGA 1WRSR 4YVIA 3OIIA 2EGWA 3KORA 4YQRA 1O6DA 1VH0A 3N4JA 3KW2A 4KGNA 4L69A 2I6DA 3N4KA 4JWJA 3G1CA 4YPZA 4KDZA 5FAIA 1VHYA 1X7OA 3SSXN 3KNUA 4YQJA 4YQ9A 4YQ3A 4YVHA 4X3MA 3QUVA 5GMBA 4E8BA 4YQBA 1UALA 1WRPR 2V3JA 3L8UA 4YQGA 2XDIA 4CNEA 1ZT9A 3E5YA 1NS5A 1WRTR 4CNDA 1UAMA 3OINA 4YQ2A 2OZ9R 2Z0YA 4FAKA 3FRWA 1ZJRA 1TRRA 4YPYA 4J3CA 1J85A 1UAKA 3KTYA 3ONPA 4YQDA 1CO0A 4JWGA 1X7PA 4RG1A 4CNFA 3NK7A 5D9FA 4X3LA 3IC6A 3WRPA 4H3ZA 1Z85A 4YQ1A 1NXZA 4YQIA 4YQ5A 1K3RA 4YQPA 4JWFA 3AI9X 4YQ6A 3KY7A 4YQNA 1VHKA 1GZ0A 2QWVA 2CX8A 3BBHA 4YQ4A 5CO4A 4XBOA 2EGVA 4YQSA 3DCMX 3SSWN 3OIJA 3ILKA 2O3AA 1MXIA 2HA8A 2V3KA 1TROA 4CNGA 3AIAA 4YQ7A 1MI7R 1UAJA 4YQAA 4YVJA 1V6ZA 3AXZA 2QMMA 2YY8A 4MCCA 1OY5A 4JWHA 4YPWA 4YQQA
chains in the Genus database with same CATH topology
4YQ8A 4YQCA 4YQTA 4YQLA 4MCBA 4IG6A 4YQKA 3IEFA 4FMWA 4H3YA 4PZKA 1P9PA 5GMCA 4YPXA 1IPAA 1TO0A 3NK6A 4JALA 3BBDA 4YVGA 4JAKA 1V2XA 3O7BA 4YQOA 4YVKA 4YQ0A 4MCDA 3GYQA 3BBEA 5GM8A 4YVIA 3OIIA 2EGWA 4YQRA 1O6DA 1VH0A 3N4JA 3KW2A 4KGNA 4L69A 2I6DA 3N4KA 4JWJA 4YPZA 4KDZA 5FAIA 1VHYA 1X7OA 3KNUA 4YQJA 4YQ9A 4YQ3A 4YVHA 4X3MA 3QUVA 5GMBA 4E8BA 4YQBA 1UALA 2V3JA 3L8UA 4YQGA 4CNEA 3E5YA 1NS5A 4CNDA 1UAMA 3OINA 4YQ2A 2Z0YA 4FAKA 1ZJRA 4YPYA 4J3CA 1J85A 1UAKA 3KTYA 3ONPA 4YQDA 4JWGA 1X7PA 4RG1A 4CNFA 3NK7A 5D9FA 4X3LA 3IC6A 4H3ZA 1Z85A 4YQ1A 1NXZA 4YQIA 4YQ5A 1K3RA 4YQPA 4JWFA 3AI9X 4YQ6A 3KY7A 4YQNA 1VHKA 1GZ0A 2QWVA 2CX8A 3BBHA 4YQ4A 5CO4A 4XBOA 2EGVA 4YQSA 3DCMX 3OIJA 3ILKA 2O3AA 1MXIA 2HA8A 2V3KA 4CNGA 3AIAA 4YQ7A 4YQAA 1UAJA 4YVJA 1V6ZA 3AXZA 2QMMA 2YY8A 4MCCA 1OY5A 4JWHA 4YPWA 4YQQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YQ8 A;  4YQC A;  4YQT A;  4YQL A;  4MCB A;  4IG6 A;  4YQK A;  3IEF A;  4PZK A;  4H3Y A;  1P9P A;  5GMC A;  4YPX A;  1IPA A;  1TO0 A;  3NK6 A;  4JAL A;  3BBD A;  4YVG A;  4JAK A;  1V2X A;  3O7B A;  4YQO A;  4YVK A;  4YQ0 A;  4MCD A;  3GYQ A;  3BBE A;  5GM8 A;  4YVI A;  3OII A;  2EGW A;  4YQR A;  1O6D A;  1VH0 A;  3N4J A;  3KW2 A;  4KGN A;  4L69 A;  2I6D A;  3N4K A;  4YPZ A;  4KDZ A;  5FAI A;  1VHY A;  1X7O A;  3KNU A;  4YQJ A;  4YQ9 A;  4YQ3 A;  4YVH A;  4X3M A;  3QUV A;  5GMB A;  4E8B A;  4YQB A;  1UAL A;  2V3J A;  3L8U A;  4YQG A;  4CNE A;  3E5Y A;  1NS5 A;  4CND A;  1UAM A;  3OIN A;  4YQ2 A;  2Z0Y A;  4FAK A;  1ZJR A;  4YPY A;  4J3C A;  1J85 A;  1UAK A;  3KTY A;  3ONP A;  4YQD A;  1X7P A;  4RG1 A;  4CNF A;  3NK7 A;  5D9F A;  4X3L A;  3IC6 A;  4H3Z A;  1Z85 A;  4YQ1 A;  1NXZ A;  4YQI A;  4YQ5 A;  1K3R A;  4YQP A;  3AI9 X;  4YQ6 A;  3KY7 A;  4YQN A;  1VHK A;  1GZ0 A;  2QWV A;  2CX8 A;  3BBH A;  4YQ4 A;  5CO4 A;  4XBO A;  2EGV A;  4YQS A;  3DCM X;  3OIJ A;  3ILK A;  2O3A A;  1MXI A;  2HA8 A;  2V3K A;  4CNG A;  3AIA A;  4YQ7 A;  4YQA A;  1UAJ A;  4YVJ A;  1V6Z A;  3AXZ A;  2QMM A;  2YY8 A;  4MCC A;  1OY5 A;  4YPW A;  4YQQ A; 
#chains in the Genus database with same CATH topology
 4YQ8 A;  4YQC A;  4YQT A;  4YQL A;  4MCB A;  4IG6 A;  4YQK A;  3IEF A;  4FMW A;  4H3Y A;  4PZK A;  1P9P A;  5GMC A;  4YPX A;  1IPA A;  1TO0 A;  3NK6 A;  4JAL A;  3BBD A;  1RCS A;  4YVG A;  4JAK A;  1V2X A;  3O7B A;  4YQO A;  4YVK A;  4YQ0 A;  4MCD A;  3GYQ A;  3BBE A;  5GM8 A;  1JHG A;  1WRS R;  4YVI A;  3OII A;  2EGW A;  3KOR A;  4YQR A;  1O6D A;  1VH0 A;  3N4J A;  3KW2 A;  4KGN A;  4L69 A;  2I6D A;  3N4K A;  4JWJ A;  3G1C A;  4YPZ A;  4KDZ A;  5FAI A;  1VHY A;  1X7O A;  3SSX N;  3KNU A;  4YQJ A;  4YQ9 A;  4YQ3 A;  4YVH A;  4X3M A;  3QUV A;  5GMB A;  4E8B A;  4YQB A;  1UAL A;  1WRP R;  2V3J A;  3L8U A;  4YQG A;  2XDI A;  4CNE A;  1ZT9 A;  3E5Y A;  1NS5 A;  1WRT R;  4CND A;  1UAM A;  3OIN A;  4YQ2 A;  2OZ9 R;  2Z0Y A;  4FAK A;  3FRW A;  1ZJR A;  1TRR A;  4YPY A;  4J3C A;  1J85 A;  1UAK A;  3KTY A;  3ONP A;  4YQD A;  1CO0 A;  4JWG A;  1X7P A;  4RG1 A;  4CNF A;  3NK7 A;  5D9F A;  4X3L A;  3IC6 A;  3WRP A;  4H3Z A;  1Z85 A;  4YQ1 A;  1NXZ A;  4YQI A;  4YQ5 A;  1K3R A;  4YQP A;  4JWF A;  3AI9 X;  4YQ6 A;  3KY7 A;  4YQN A;  1VHK A;  1GZ0 A;  2QWV A;  2CX8 A;  3BBH A;  4YQ4 A;  5CO4 A;  4XBO A;  2EGV A;  4YQS A;  3DCM X;  3SSW N;  3OIJ A;  3ILK A;  2O3A A;  1MXI A;  2HA8 A;  2V3K A;  1TRO A;  4CNG A;  3AIA A;  4YQ7 A;  1MI7 R;  1UAJ A;  4YQA A;  4YVJ A;  1V6Z A;  3AXZ A;  2QMM A;  2YY8 A;  4MCC A;  1OY5 A;  4JWH A;  4YPW A;  4YQQ A; 
#chains in the Genus database with same CATH homology
 4YQ8 A;  4YQC A;  4YQT A;  4YQL A;  4MCB A;  4IG6 A;  4YQK A;  3IEF A;  4FMW A;  4H3Y A;  4PZK A;  1P9P A;  5GMC A;  4YPX A;  1IPA A;  1TO0 A;  3NK6 A;  4JAL A;  3BBD A;  4YVG A;  4JAK A;  1V2X A;  3O7B A;  4YQO A;  4YVK A;  4YQ0 A;  4MCD A;  3GYQ A;  3BBE A;  5GM8 A;  4YVI A;  3OII A;  2EGW A;  4YQR A;  1O6D A;  1VH0 A;  3N4J A;  3KW2 A;  4KGN A;  4L69 A;  2I6D A;  3N4K A;  4JWJ A;  4YPZ A;  4KDZ A;  5FAI A;  1VHY A;  1X7O A;  3KNU A;  4YQJ A;  4YQ9 A;  4YQ3 A;  4YVH A;  4X3M A;  3QUV A;  5GMB A;  4E8B A;  4YQB A;  1UAL A;  2V3J A;  3L8U A;  4YQG A;  4CNE A;  3E5Y A;  1NS5 A;  4CND A;  1UAM A;  3OIN A;  4YQ2 A;  2Z0Y A;  4FAK A;  1ZJR A;  4YPY A;  4J3C A;  1J85 A;  1UAK A;  3KTY A;  3ONP A;  4YQD A;  4JWG A;  1X7P A;  4RG1 A;  4CNF A;  3NK7 A;  5D9F A;  4X3L A;  3IC6 A;  4H3Z A;  1Z85 A;  4YQ1 A;  1NXZ A;  4YQI A;  4YQ5 A;  1K3R A;  4YQP A;  4JWF A;  3AI9 X;  4YQ6 A;  3KY7 A;  4YQN A;  1VHK A;  1GZ0 A;  2QWV A;  2CX8 A;  3BBH A;  4YQ4 A;  5CO4 A;  4XBO A;  2EGV A;  4YQS A;  3DCM X;  3OIJ A;  3ILK A;  2O3A A;  1MXI A;  2HA8 A;  2V3K A;  4CNG A;  3AIA A;  4YQ7 A;  4YQA A;  1UAJ A;  4YVJ A;  1V6Z A;  3AXZ A;  2QMM A;  2YY8 A;  4MCC A;  1OY5 A;  4JWH A;  4YPW A;  4YQQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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