4H3ZA

Crystal structure of a symmetric dimer of a trna (guanine-(n(1)-)-methyltransferase from burkholderia phymatum bound to s-adenosyl homocystein in both half-sites
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
Knots found
sequence length
255
structure length
249
Chain Sequence
SMQFDIVTLFPDMFRALTDWGITSRAAKQERYGLRTWNPRDFTTDNYRTIDDRPYGGGPGMVMLARPLEDAINAAKAAQAEQGIGGARVVMMSPQGATLNHDKVMRFAAEPGLILLCGRYEAIDQRLIDRVVDEEVSLGDFVLSGGELPAMALIDAVVRHLPGVLNQDSFVDGLLDCPHYTRPEEYDGVRVPDVLLGGHHAEIEQWRRREALRNTWLKRPDLIVQARKNKLLSRADEAWLASLAKDASK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
publication title Combining functional and structural genomics to sample the essential Burkholderia structome.
pubmed doi rcsb
source organism Burkholderia phymatum
total genus 81
structure length 249
sequence length 255
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2012-09-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4h3zA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4h3zA01
1V6ZA 4YVKA 3IEFA 2O3AA 1X7OA 4YPXA 4YVGA 4YVJA 3O7BA 3KY7A 1OY5A 3E5YA 4YQNA 2YY8A 2EGVA 1NXZA 3OIIA 4YVHA 4CNGA 3AXZA 4E8BA 4YQ6A 4YQRA 1Z85A 1O6DA 2I6DA 5FAIA 4YQCA 1VHKA 4CNEA 2EGWA 4L69A 4YQAA 4MCBA 1NS5A 3BBDA 1IPAA 1K3RA 4MCCA 1X7PA 4YQ8A 3BBHA 4MCDA 3N4JA 1UAMA 1UALA 5CO4A 1UAJA 3KNUA 4YQ2A 1VH0A 3N4KA 3KTYA 4JALA 4YQBA 3NK6A 4KGNA 2QWVA 4J3CA 3OIJA 1P9PA 4FAKA 4H3YA 4KDZA 3ILKA 5GM8A 2HA8A 3IC6A 4YVIA 3OINA 3GYQA 1MXIA 4YQ0A 4XBOA 4JAKA 3QUVA 4YQLA 5GMBA 4YQPA 4IG6A 1UAKA 3ONPA 4YQIA 4YQ3A 1GZ0A 4PZKA 4YQTA 4RG1A 1ZJRA 4YQOA 4CNFA 4YQQA 2QMMA 4YPYA 3AI9X 1VHYA 4YPZA 4YQKA 1TO0A 4YQGA 5D9FA 3DCMX 1J85A 5GMCA 2V3KA 4YQ9A 4YQ4A 4YQ1A 4CNDA 4YQ5A 2Z0YA 1V2XA 4X3MA 4YQSA 3KW2A 3L8UA 2CX8A 4YPWA 4X3LA 2V3JA 4YQ7A 4YQDA 3AIAA 3NK7A 4H3ZA 4YQJA 3BBEA
chains in the Genus database with same CATH superfamily
3WRPA 1V6ZA 4YVKA 3SSWN 3IEFA 2O3AA 1X7OA 4YPXA 4YVGA 4YVJA 3O7BA 3KY7A 1OY5A 3E5YA 3G1CA 4YQNA 2YY8A 2EGVA 1NXZA 3OIIA 4YVHA 4CNGA 3AXZA 4E8BA 4YQ6A 4YQRA 1Z85A 1O6DA 2I6DA 3BBEA 5FAIA 4YQCA 1VHKA 4CNEA 1JHGA 2EGWA 4L69A 4YQAA 1CO0A 4MCBA 1NS5A 3BBDA 1IPAA 1ZT9A 4MCCA 1K3RA 1X7PA 4YQ8A 3BBHA 4MCDA 3N4JA 1WRTR 1UAMA 1RCSA 1UALA 5CO4A 3FRWA 1UAJA 3KNUA 4YQ2A 1VH0A 3N4KA 3KTYA 4JALA 4YQBA 3NK6A 4KGNA 2QWVA 4J3CA 4JWHA 3OIJA 1P9PA 4FAKA 4H3YA 4KDZA 3ILKA 4JWGA 2HA8A 5GM8A 3IC6A 4YVIA 3OINA 3GYQA 1MXIA 4YQ0A 4XBOA 4JAKA 3QUVA 4YQLA 5GMBA 4YQPA 4JWJA 4IG6A 1TRRA 1UAKA 3ONPA 4YQIA 4YQ3A 2XDIA 1GZ0A 4PZKA 4YQTA 4RG1A 1ZJRA 4YQOA 4CNFA 4YQQA 2QMMA 4YPYA 3AI9X 1VHYA 4YPZA 4YQKA 1WRSR 1MI7R 1TO0A 4YQGA 5D9FA 3DCMX 1J85A 5GMCA 2V3KA 4YQ9A 1WRPR 4YQ4A 4YQ1A 4CNDA 3KORA 4YQ5A 2Z0YA 1V2XA 4X3MA 4YQSA 3KW2A 3L8UA 2CX8A 4YPWA 4X3LA 2V3JA 4YQ7A 4YQDA 4FMWA 1TROA 4JWFA 3AIAA 3NK7A 3SSXN 4H3ZA 4YQJA 2OZ9R
chains in the Genus database with same CATH topology
1V6ZA 4YVKA 3IEFA 2O3AA 1X7OA 4YPXA 4YVGA 4YVJA 3O7BA 3KY7A 1OY5A 3E5YA 4YQNA 2YY8A 2EGVA 1NXZA 3OIIA 4YVHA 4CNGA 3AXZA 4E8BA 4YQ6A 4YQRA 1Z85A 1O6DA 2I6DA 5FAIA 4YQCA 1VHKA 4CNEA 2EGWA 4L69A 4YQAA 4MCBA 1NS5A 3BBDA 1IPAA 1K3RA 4MCCA 1X7PA 4YQ8A 3BBHA 4MCDA 3N4JA 1UAMA 1UALA 5CO4A 1UAJA 3KNUA 4YQ2A 1VH0A 3N4KA 3KTYA 4JALA 4YQBA 3NK6A 4KGNA 2QWVA 4J3CA 4JWHA 3OIJA 1P9PA 4FAKA 4H3YA 4KDZA 3ILKA 4JWGA 2HA8A 5GM8A 3IC6A 4YVIA 3OINA 3GYQA 1MXIA 4YQ0A 4XBOA 4JAKA 3QUVA 4YQLA 5GMBA 4YQPA 4JWJA 4IG6A 1UAKA 3ONPA 4YQIA 4YQ3A 1GZ0A 4PZKA 4YQTA 4RG1A 1ZJRA 4YQOA 4CNFA 4YQQA 2QMMA 4YPYA 3AI9X 1VHYA 4YPZA 4YQKA 1TO0A 4YQGA 5D9FA 3DCMX 1J85A 5GMCA 2V3KA 4YQ9A 4YQ4A 4YQ1A 4CNDA 4YQ5A 2Z0YA 1V2XA 4X3MA 4YQSA 3KW2A 3L8UA 2CX8A 4YPWA 4X3LA 2V3JA 4YQ7A 4YQDA 4FMWA 4JWFA 3AIAA 3NK7A 4H3ZA 4YQJA 3BBEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1V6Z A;  4YVK A;  3IEF A;  2O3A A;  1X7O A;  4YPX A;  4YVG A;  4YVJ A;  3O7B A;  3KY7 A;  1OY5 A;  3E5Y A;  4YQN A;  2YY8 A;  2EGV A;  1NXZ A;  3OII A;  4YVH A;  4CNG A;  3AXZ A;  4E8B A;  4YQ6 A;  4YQR A;  1Z85 A;  1O6D A;  2I6D A;  5FAI A;  4YQC A;  1VHK A;  4CNE A;  2EGW A;  4L69 A;  4YQA A;  4MCB A;  1NS5 A;  3BBD A;  1IPA A;  1K3R A;  4MCC A;  1X7P A;  4YQ8 A;  3BBH A;  4MCD A;  3N4J A;  1UAM A;  1UAL A;  5CO4 A;  1UAJ A;  3KNU A;  4YQ2 A;  1VH0 A;  3N4K A;  3KTY A;  4JAL A;  4YQB A;  3NK6 A;  4KGN A;  2QWV A;  4J3C A;  3OIJ A;  1P9P A;  4FAK A;  4H3Y A;  4KDZ A;  3ILK A;  5GM8 A;  2HA8 A;  3IC6 A;  4YVI A;  3OIN A;  3GYQ A;  1MXI A;  4YQ0 A;  4XBO A;  4JAK A;  3QUV A;  4YQL A;  5GMB A;  4YQP A;  4IG6 A;  1UAK A;  3ONP A;  4YQI A;  4YQ3 A;  1GZ0 A;  4PZK A;  4YQT A;  4RG1 A;  1ZJR A;  4YQO A;  4CNF A;  4YQQ A;  2QMM A;  4YPY A;  3AI9 X;  1VHY A;  4YPZ A;  4YQK A;  1TO0 A;  4YQG A;  5D9F A;  3DCM X;  1J85 A;  5GMC A;  2V3K A;  4YQ9 A;  4YQ4 A;  4YQ1 A;  4CND A;  4YQ5 A;  2Z0Y A;  1V2X A;  4X3M A;  4YQS A;  3KW2 A;  3L8U A;  2CX8 A;  4YPW A;  4X3L A;  2V3J A;  4YQ7 A;  4YQD A;  3AIA A;  3NK7 A;  4H3Z A;  4YQJ A;  3BBE A; 
#chains in the Genus database with same CATH topology
 3WRP A;  1V6Z A;  4YVK A;  3SSW N;  3IEF A;  2O3A A;  1X7O A;  4YPX A;  4YVG A;  4YVJ A;  3O7B A;  3KY7 A;  1OY5 A;  3E5Y A;  3G1C A;  4YQN A;  2YY8 A;  2EGV A;  1NXZ A;  3OII A;  4YVH A;  4CNG A;  3AXZ A;  4E8B A;  4YQ6 A;  4YQR A;  1Z85 A;  1O6D A;  2I6D A;  3BBE A;  5FAI A;  4YQC A;  1VHK A;  4CNE A;  1JHG A;  2EGW A;  4L69 A;  4YQA A;  1CO0 A;  4MCB A;  1NS5 A;  3BBD A;  1IPA A;  1ZT9 A;  4MCC A;  1K3R A;  1X7P A;  4YQ8 A;  3BBH A;  4MCD A;  3N4J A;  1WRT R;  1UAM A;  1RCS A;  1UAL A;  5CO4 A;  3FRW A;  1UAJ A;  3KNU A;  4YQ2 A;  1VH0 A;  3N4K A;  3KTY A;  4JAL A;  4YQB A;  3NK6 A;  4KGN A;  2QWV A;  4J3C A;  4JWH A;  3OIJ A;  1P9P A;  4FAK A;  4H3Y A;  4KDZ A;  3ILK A;  4JWG A;  2HA8 A;  5GM8 A;  3IC6 A;  4YVI A;  3OIN A;  3GYQ A;  1MXI A;  4YQ0 A;  4XBO A;  4JAK A;  3QUV A;  4YQL A;  5GMB A;  4YQP A;  4JWJ A;  4IG6 A;  1TRR A;  1UAK A;  3ONP A;  4YQI A;  4YQ3 A;  2XDI A;  1GZ0 A;  4PZK A;  4YQT A;  4RG1 A;  1ZJR A;  4YQO A;  4CNF A;  4YQQ A;  2QMM A;  4YPY A;  3AI9 X;  1VHY A;  4YPZ A;  4YQK A;  1WRS R;  1MI7 R;  1TO0 A;  4YQG A;  5D9F A;  3DCM X;  1J85 A;  5GMC A;  2V3K A;  4YQ9 A;  1WRP R;  4YQ4 A;  4YQ1 A;  4CND A;  3KOR A;  4YQ5 A;  2Z0Y A;  1V2X A;  4X3M A;  4YQS A;  3KW2 A;  3L8U A;  2CX8 A;  4YPW A;  4X3L A;  2V3J A;  4YQ7 A;  4YQD A;  4FMW A;  1TRO A;  4JWF A;  3AIA A;  3NK7 A;  3SSX N;  4H3Z A;  4YQJ A;  2OZ9 R; 
#chains in the Genus database with same CATH homology
 1V6Z A;  4YVK A;  3IEF A;  2O3A A;  1X7O A;  4YPX A;  4YVG A;  4YVJ A;  3O7B A;  3KY7 A;  1OY5 A;  3E5Y A;  4YQN A;  2YY8 A;  2EGV A;  1NXZ A;  3OII A;  4YVH A;  4CNG A;  3AXZ A;  4E8B A;  4YQ6 A;  4YQR A;  1Z85 A;  1O6D A;  2I6D A;  5FAI A;  4YQC A;  1VHK A;  4CNE A;  2EGW A;  4L69 A;  4YQA A;  4MCB A;  1NS5 A;  3BBD A;  1IPA A;  1K3R A;  4MCC A;  1X7P A;  4YQ8 A;  3BBH A;  4MCD A;  3N4J A;  1UAM A;  1UAL A;  5CO4 A;  1UAJ A;  3KNU A;  4YQ2 A;  1VH0 A;  3N4K A;  3KTY A;  4JAL A;  4YQB A;  3NK6 A;  4KGN A;  2QWV A;  4J3C A;  4JWH A;  3OIJ A;  1P9P A;  4FAK A;  4H3Y A;  4KDZ A;  3ILK A;  4JWG A;  2HA8 A;  5GM8 A;  3IC6 A;  4YVI A;  3OIN A;  3GYQ A;  1MXI A;  4YQ0 A;  4XBO A;  4JAK A;  3QUV A;  4YQL A;  5GMB A;  4YQP A;  4JWJ A;  4IG6 A;  1UAK A;  3ONP A;  4YQI A;  4YQ3 A;  1GZ0 A;  4PZK A;  4YQT A;  4RG1 A;  1ZJR A;  4YQO A;  4CNF A;  4YQQ A;  2QMM A;  4YPY A;  3AI9 X;  1VHY A;  4YPZ A;  4YQK A;  1TO0 A;  4YQG A;  5D9F A;  3DCM X;  1J85 A;  5GMC A;  2V3K A;  4YQ9 A;  4YQ4 A;  4YQ1 A;  4CND A;  4YQ5 A;  2Z0Y A;  1V2X A;  4X3M A;  4YQS A;  3KW2 A;  3L8U A;  2CX8 A;  4YPW A;  4X3L A;  2V3J A;  4YQ7 A;  4YQD A;  4FMW A;  4JWF A;  3AIA A;  3NK7 A;  4H3Z A;  4YQJ A;  3BBE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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