5D9FA

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
248
structure length
237
Chain Sequence
GSHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGDGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 69
structure length 237
sequence length 248
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-08-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 5d9fA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 5d9fA01
3L8UA 1UALA 4YQGA 4YQ7A 1UAJA 1P9PA 5CO4A 4YVIA 4YVGA 1MXIA 3ONPA 4YVJA 4PZKA 3NK7A 4YQJA 4XBOA 4YQAA 4YQ3A 1GZ0A 4YVHA 1OY5A 2CX8A 4YQIA 3N4JA 2V3KA 5FAIA 3O7BA 1VH0A 4YQ4A 1UAMA 4IG6A 4YQTA 3ILKA 3DCMX 1NS5A 3AI9X 3BBEA 1IPAA 1VHKA 3KTYA 3GYQA 4YQSA 5GMCA 4YQOA 4RG1A 4J3CA 4X3MA 4YQPA 4YQCA 4YPZA 1J85A 4CNFA 5GM8A 4YQ5A 4YQ6A 4YQQA 4YVKA 1X7OA 4MCDA 1K3RA 3QUVA 1V6ZA 4E8BA 4YPXA 4KDZA 2HA8A 4H3YA 2Z0YA 3OIJA 5D9FA 3IEFA 3IC6A 3KY7A 1NXZA 4YQ0A 2V3JA 4YQKA 4YQDA 3BBHA 4YPYA 4H3ZA 4YQNA 1O6DA 2O3AA 4YQLA 4YQRA 2QWVA 1X7PA 4YQ2A 4MCBA 2QMMA 3OIIA 2YY8A 1VHYA 4CNDA 4MCCA 4YPWA 4YQBA 3AIAA 1UAKA 4YQ8A 4JAKA 3KW2A 1V2XA 1ZJRA 2EGWA 2I6DA 3NK6A 4JALA 1TO0A 4CNEA 4FAKA 4L69A 4KGNA 3OINA 2EGVA 3E5YA 1Z85A 3BBDA 3N4KA 4CNGA 4YQ9A 5GMBA 4YQ1A 4X3LA 3KNUA 3AXZA
chains in the Genus database with same CATH superfamily
3L8UA 1UALA 4YQGA 4YQ7A 1UAJA 1P9PA 5CO4A 4YVIA 4YVGA 1MXIA 3ONPA 4JWJA 4YVJA 4PZKA 1TRRA 1WRTR 3NK7A 4YQJA 4XBOA 4YQAA 4YQ3A 1WRSR 1GZ0A 4YVHA 1OY5A 2CX8A 4YQIA 3N4JA 2V3KA 3KORA 5FAIA 3O7BA 1VH0A 4YQ4A 1UAMA 4IG6A 4YQTA 3ILKA 3DCMX 1NS5A 3AI9X 3BBEA 1IPAA 1VHKA 3KTYA 3GYQA 4YQSA 5GMCA 4YQOA 4JWHA 4RG1A 4J3CA 4X3MA 4YQPA 4YQCA 4YPZA 1J85A 1JHGA 4FMWA 4CNFA 5GM8A 4YQ5A 4YQ6A 4YQQA 1MI7R 4YVKA 1X7OA 4MCDA 1K3RA 2XDIA 3QUVA 1WRPR 1V6ZA 4YPXA 4E8BA 4KDZA 2HA8A 4H3YA 2Z0YA 1ZT9A 3OIJA 5D9FA 3IEFA 3IC6A 3G1CA 3KY7A 3SSWN 1NXZA 4JWGA 4JWFA 4YQ0A 2V3JA 4YQKA 4YQDA 3BBHA 4YPYA 1TROA 4H3ZA 4YQNA 1O6DA 2O3AA 4YQLA 4YQRA 2QWVA 1X7PA 4YQ2A 4MCBA 2QMMA 3OIIA 2YY8A 1VHYA 1CO0A 4CNDA 4MCCA 3FRWA 4YPWA 4YQBA 3AIAA 1UAKA 4YQ8A 4JAKA 3KW2A 1V2XA 1ZJRA 2EGWA 2I6DA 3NK6A 4JALA 1TO0A 4CNEA 4FAKA 4L69A 4KGNA 3OINA 2EGVA 3E5YA 3WRPA 1RCSA 1Z85A 3BBDA 3N4KA 4CNGA 4YQ9A 5GMBA 2OZ9R 4YQ1A 4X3LA 3SSXN 3KNUA 3AXZA
chains in the Genus database with same CATH topology
3L8UA 1UALA 4YQGA 4YQ7A 1UAJA 1P9PA 5CO4A 4YVIA 4YVGA 1MXIA 3ONPA 4JWJA 4YVJA 4PZKA 3NK7A 4YQJA 4XBOA 4YQAA 4YQ3A 1GZ0A 4YVHA 1OY5A 2CX8A 4YQIA 3N4JA 2V3KA 5FAIA 3O7BA 1VH0A 4YQ4A 1UAMA 4IG6A 4YQTA 3ILKA 3DCMX 1NS5A 3AI9X 3BBEA 1IPAA 1VHKA 3KTYA 3GYQA 4YQSA 5GMCA 4YQOA 4JWHA 4RG1A 4J3CA 4X3MA 4YQPA 4YQCA 4YPZA 1J85A 4FMWA 4CNFA 5GM8A 4YQ5A 4YQ6A 4YQQA 4YVKA 1X7OA 4MCDA 1K3RA 3QUVA 1V6ZA 4E8BA 4YPXA 4KDZA 2HA8A 4H3YA 2Z0YA 3OIJA 5D9FA 3IEFA 3IC6A 3KY7A 1NXZA 4JWGA 4JWFA 4YQ0A 2V3JA 4YQKA 4YQDA 3BBHA 4YPYA 4H3ZA 4YQNA 1O6DA 2O3AA 4YQLA 4YQRA 2QWVA 1X7PA 4YQ2A 4MCBA 2QMMA 3OIIA 2YY8A 1VHYA 4CNDA 4MCCA 4YPWA 4YQBA 3AIAA 1UAKA 4YQ8A 4JAKA 3KW2A 1V2XA 1ZJRA 2EGWA 2I6DA 3NK6A 4JALA 1TO0A 4CNEA 4FAKA 4L69A 4KGNA 3OINA 2EGVA 3E5YA 1Z85A 3BBDA 3N4KA 4CNGA 4YQ9A 5GMBA 4YQ1A 4X3LA 3KNUA 3AXZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3L8U A;  1UAL A;  4YQG A;  4YQ7 A;  1UAJ A;  1P9P A;  5CO4 A;  4YVI A;  4YVG A;  1MXI A;  3ONP A;  4YVJ A;  4PZK A;  3NK7 A;  4YQJ A;  4XBO A;  4YQA A;  4YQ3 A;  1GZ0 A;  4YVH A;  1OY5 A;  2CX8 A;  4YQI A;  3N4J A;  2V3K A;  5FAI A;  3O7B A;  1VH0 A;  4YQ4 A;  1UAM A;  4IG6 A;  4YQT A;  3ILK A;  3DCM X;  1NS5 A;  3AI9 X;  3BBE A;  1IPA A;  1VHK A;  3KTY A;  3GYQ A;  4YQS A;  5GMC A;  4YQO A;  4RG1 A;  4J3C A;  4X3M A;  4YQP A;  4YQC A;  4YPZ A;  1J85 A;  4CNF A;  5GM8 A;  4YQ5 A;  4YQ6 A;  4YQQ A;  4YVK A;  1X7O A;  4MCD A;  1K3R A;  3QUV A;  1V6Z A;  4E8B A;  4YPX A;  4KDZ A;  2HA8 A;  4H3Y A;  2Z0Y A;  3OIJ A;  5D9F A;  3IEF A;  3IC6 A;  3KY7 A;  1NXZ A;  4YQ0 A;  2V3J A;  4YQK A;  4YQD A;  3BBH A;  4YPY A;  4H3Z A;  4YQN A;  1O6D A;  2O3A A;  4YQL A;  4YQR A;  2QWV A;  1X7P A;  4YQ2 A;  4MCB A;  2QMM A;  3OII A;  2YY8 A;  1VHY A;  4CND A;  4MCC A;  4YPW A;  4YQB A;  3AIA A;  1UAK A;  4YQ8 A;  4JAK A;  3KW2 A;  1V2X A;  1ZJR A;  2EGW A;  2I6D A;  3NK6 A;  4JAL A;  1TO0 A;  4CNE A;  4FAK A;  4L69 A;  4KGN A;  3OIN A;  2EGV A;  3E5Y A;  1Z85 A;  3BBD A;  3N4K A;  4CNG A;  4YQ9 A;  5GMB A;  4YQ1 A;  4X3L A;  3KNU A;  3AXZ A; 
#chains in the Genus database with same CATH topology
 3L8U A;  1UAL A;  4YQG A;  4YQ7 A;  1UAJ A;  1P9P A;  5CO4 A;  4YVI A;  4YVG A;  1MXI A;  3ONP A;  4JWJ A;  4YVJ A;  4PZK A;  1TRR A;  1WRT R;  3NK7 A;  4YQJ A;  4XBO A;  4YQA A;  4YQ3 A;  1WRS R;  1GZ0 A;  4YVH A;  1OY5 A;  2CX8 A;  4YQI A;  3N4J A;  2V3K A;  3KOR A;  5FAI A;  3O7B A;  1VH0 A;  4YQ4 A;  1UAM A;  4IG6 A;  4YQT A;  3ILK A;  3DCM X;  1NS5 A;  3AI9 X;  3BBE A;  1IPA A;  1VHK A;  3KTY A;  3GYQ A;  4YQS A;  5GMC A;  4YQO A;  4JWH A;  4RG1 A;  4J3C A;  4X3M A;  4YQP A;  4YQC A;  4YPZ A;  1J85 A;  1JHG A;  4FMW A;  4CNF A;  5GM8 A;  4YQ5 A;  4YQ6 A;  4YQQ A;  1MI7 R;  4YVK A;  1X7O A;  4MCD A;  1K3R A;  2XDI A;  3QUV A;  1WRP R;  1V6Z A;  4YPX A;  4E8B A;  4KDZ A;  2HA8 A;  4H3Y A;  2Z0Y A;  1ZT9 A;  3OIJ A;  5D9F A;  3IEF A;  3IC6 A;  3G1C A;  3KY7 A;  3SSW N;  1NXZ A;  4JWG A;  4JWF A;  4YQ0 A;  2V3J A;  4YQK A;  4YQD A;  3BBH A;  4YPY A;  1TRO A;  4H3Z A;  4YQN A;  1O6D A;  2O3A A;  4YQL A;  4YQR A;  2QWV A;  1X7P A;  4YQ2 A;  4MCB A;  2QMM A;  3OII A;  2YY8 A;  1VHY A;  1CO0 A;  4CND A;  4MCC A;  3FRW A;  4YPW A;  4YQB A;  3AIA A;  1UAK A;  4YQ8 A;  4JAK A;  3KW2 A;  1V2X A;  1ZJR A;  2EGW A;  2I6D A;  3NK6 A;  4JAL A;  1TO0 A;  4CNE A;  4FAK A;  4L69 A;  4KGN A;  3OIN A;  2EGV A;  3E5Y A;  3WRP A;  1RCS A;  1Z85 A;  3BBD A;  3N4K A;  4CNG A;  4YQ9 A;  5GMB A;  2OZ9 R;  4YQ1 A;  4X3L A;  3SSX N;  3KNU A;  3AXZ A; 
#chains in the Genus database with same CATH homology
 3L8U A;  1UAL A;  4YQG A;  4YQ7 A;  1UAJ A;  1P9P A;  5CO4 A;  4YVI A;  4YVG A;  1MXI A;  3ONP A;  4JWJ A;  4YVJ A;  4PZK A;  3NK7 A;  4YQJ A;  4XBO A;  4YQA A;  4YQ3 A;  1GZ0 A;  4YVH A;  1OY5 A;  2CX8 A;  4YQI A;  3N4J A;  2V3K A;  5FAI A;  3O7B A;  1VH0 A;  4YQ4 A;  1UAM A;  4IG6 A;  4YQT A;  3ILK A;  3DCM X;  1NS5 A;  3AI9 X;  3BBE A;  1IPA A;  1VHK A;  3KTY A;  3GYQ A;  4YQS A;  5GMC A;  4YQO A;  4JWH A;  4RG1 A;  4J3C A;  4X3M A;  4YQP A;  4YQC A;  4YPZ A;  1J85 A;  4FMW A;  4CNF A;  5GM8 A;  4YQ5 A;  4YQ6 A;  4YQQ A;  4YVK A;  1X7O A;  4MCD A;  1K3R A;  3QUV A;  1V6Z A;  4E8B A;  4YPX A;  4KDZ A;  2HA8 A;  4H3Y A;  2Z0Y A;  3OIJ A;  5D9F A;  3IEF A;  3IC6 A;  3KY7 A;  1NXZ A;  4JWG A;  4JWF A;  4YQ0 A;  2V3J A;  4YQK A;  4YQD A;  3BBH A;  4YPY A;  4H3Z A;  4YQN A;  1O6D A;  2O3A A;  4YQL A;  4YQR A;  2QWV A;  1X7P A;  4YQ2 A;  4MCB A;  2QMM A;  3OII A;  2YY8 A;  1VHY A;  4CND A;  4MCC A;  4YPW A;  4YQB A;  3AIA A;  1UAK A;  4YQ8 A;  4JAK A;  3KW2 A;  1V2X A;  1ZJR A;  2EGW A;  2I6D A;  3NK6 A;  4JAL A;  1TO0 A;  4CNE A;  4FAK A;  4L69 A;  4KGN A;  3OIN A;  2EGV A;  3E5Y A;  1Z85 A;  3BBD A;  3N4K A;  4CNG A;  4YQ9 A;  5GMB A;  4YQ1 A;  4X3L A;  3KNU A;  3AXZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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