4YQOA

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
254
structure length
242
Chain Sequence
GLVPRGSHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLDGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 71
structure length 242
sequence length 254
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4yqoA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4yqoA01
1OY5A 4YQQA 1UALA 4JAKA 5D9FA 4YQTA 3OIIA 4YQ2A 1P9PA 1TO0A 4YQ7A 4YQ9A 4H3ZA 4YQRA 4YQAA 4YQOA 3BBEA 2V3KA 1O6DA 4YVKA 4H3YA 2YY8A 4YQIA 1VHKA 4FAKA 4YQPA 4KDZA 3KTYA 4YVJA 2QWVA 4YQSA 3IC6A 2CX8A 4YQ1A 1UAKA 3O7BA 4CNFA 3ILKA 3E5YA 4YQ0A 1NXZA 4YQDA 1V6ZA 2V3JA 3ONPA 3OIJA 4RG1A 4X3MA 2EGWA 1J85A 1V2XA 3BBHA 4MCBA 4CNDA 3AI9X 4JALA 4YQKA 4YQ4A 4E8BA 1ZJRA 3GYQA 3N4KA 1IPAA 3AXZA 4YQ6A 4YQCA 4YQJA 4CNEA 1MXIA 3AIAA 4IG6A 2Z0YA 2O3AA 4YQ3A 5CO4A 3NK7A 4MCDA 4YVHA 4YQGA 3N4JA 1VHYA 1VH0A 4L69A 5GM8A 4J3CA 2QMMA 3BBDA 1X7OA 5FAIA 1GZ0A 4CNGA 1UAJA 4YQLA 5GMBA 4PZKA 1X7PA 3KNUA 4XBOA 3KY7A 3OINA 3IEFA 4MCCA 4YPWA 1NS5A 3NK6A 5GMCA 1UAMA 2HA8A 4X3LA 4YQ5A 4KGNA 2EGVA 3L8UA 3QUVA 1Z85A 4YQBA 3KW2A 4YPYA 4YQ8A 4YPZA 4YVIA 4YVGA 4YPXA 4YQNA 2I6DA 3DCMX 1K3RA
chains in the Genus database with same CATH superfamily
4FMWA 1OY5A 4YQQA 1UALA 4JAKA 5D9FA 4JWJA 4YQTA 3OIIA 4YQ2A 1P9PA 1TO0A 4YQ7A 4YQ9A 4H3ZA 4YQRA 4YQAA 4YQOA 3BBEA 4JWGA 2V3KA 1O6DA 4YVKA 4H3YA 2YY8A 4YQIA 3G1CA 1VHKA 4FAKA 3SSXN 4YQPA 4KDZA 3KTYA 4YVJA 2QWVA 4YQSA 3IC6A 2CX8A 4YQ1A 1UAKA 3O7BA 1TRRA 4CNFA 3ILKA 1CO0A 3E5YA 4YQ0A 1NXZA 4YQDA 1RCSA 1V6ZA 2V3JA 3SSWN 3ONPA 3WRPA 1MI7R 3OIJA 3KORA 1WRPR 4RG1A 4X3MA 2EGWA 1J85A 1V2XA 4JWHA 3BBHA 1WRSR 4MCBA 1TROA 4CNDA 3AI9X 4JALA 4YQKA 4YQ4A 1ZT9A 4E8BA 1ZJRA 3GYQA 3N4KA 1IPAA 3AXZA 4YQ6A 4YQCA 4YQJA 4CNEA 1MXIA 3AIAA 4IG6A 2Z0YA 2O3AA 4YQ3A 5CO4A 1WRTR 3FRWA 3NK7A 4MCDA 4YVHA 4YQGA 3N4JA 1VHYA 1VH0A 4JWFA 2XDIA 4L69A 5GM8A 4J3CA 2QMMA 3BBDA 1X7OA 5FAIA 1GZ0A 4CNGA 1UAJA 4YQLA 5GMBA 4PZKA 1X7PA 3KNUA 4XBOA 3KY7A 3OINA 3IEFA 4MCCA 4YPWA 2OZ9R 1NS5A 3NK6A 5GMCA 1UAMA 2HA8A 4X3LA 4YQ5A 4KGNA 2EGVA 3L8UA 3QUVA 1Z85A 4YQBA 3KW2A 4YPYA 4YQ8A 1JHGA 4YPZA 4YVIA 4YVGA 4YPXA 4YQNA 2I6DA 3DCMX 1K3RA
chains in the Genus database with same CATH topology
4FMWA 1OY5A 4YQQA 1UALA 4JAKA 5D9FA 4JWJA 4YQTA 3OIIA 4YQ2A 1P9PA 1TO0A 4YQ7A 4YQ9A 4H3ZA 4YQRA 4YQAA 4YQOA 3BBEA 4JWGA 2V3KA 1O6DA 4YVKA 4H3YA 2YY8A 4YQIA 1VHKA 4FAKA 4YQPA 4KDZA 3KTYA 4YVJA 2QWVA 4YQSA 3IC6A 2CX8A 4YQ1A 1UAKA 3O7BA 4CNFA 3ILKA 3E5YA 4YQ0A 1NXZA 4YQDA 1V6ZA 2V3JA 3ONPA 3OIJA 4RG1A 4X3MA 2EGWA 1J85A 1V2XA 4JWHA 3BBHA 4MCBA 4CNDA 3AI9X 4JALA 4YQKA 4YQ4A 4E8BA 1ZJRA 3GYQA 3N4KA 1IPAA 3AXZA 4YQ6A 4YQCA 4YQJA 4CNEA 1MXIA 3AIAA 4IG6A 2Z0YA 2O3AA 4YQ3A 5CO4A 3NK7A 4MCDA 4YVHA 4YQGA 3N4JA 1VHYA 1VH0A 4JWFA 4L69A 5GM8A 4J3CA 2QMMA 3BBDA 1X7OA 5FAIA 1GZ0A 4CNGA 1UAJA 4YQLA 5GMBA 4PZKA 1X7PA 3KNUA 4XBOA 3KY7A 3OINA 3IEFA 4MCCA 4YPWA 1NS5A 3NK6A 5GMCA 1UAMA 2HA8A 4X3LA 4YQ5A 4KGNA 2EGVA 3L8UA 3QUVA 1Z85A 4YQBA 3KW2A 4YPYA 4YQ8A 4YPZA 4YVIA 4YVGA 4YPXA 4YQNA 2I6DA 3DCMX 1K3RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OY5 A;  4YQQ A;  1UAL A;  4JAK A;  5D9F A;  4YQT A;  3OII A;  4YQ2 A;  1P9P A;  1TO0 A;  4YQ7 A;  4YQ9 A;  4H3Z A;  4YQR A;  4YQA A;  4YQO A;  3BBE A;  2V3K A;  1O6D A;  4YVK A;  4H3Y A;  2YY8 A;  4YQI A;  1VHK A;  4FAK A;  4YQP A;  4KDZ A;  3KTY A;  4YVJ A;  2QWV A;  4YQS A;  3IC6 A;  2CX8 A;  4YQ1 A;  1UAK A;  3O7B A;  4CNF A;  3ILK A;  3E5Y A;  4YQ0 A;  1NXZ A;  4YQD A;  1V6Z A;  2V3J A;  3ONP A;  3OIJ A;  4RG1 A;  4X3M A;  2EGW A;  1J85 A;  1V2X A;  3BBH A;  4MCB A;  4CND A;  3AI9 X;  4JAL A;  4YQK A;  4YQ4 A;  4E8B A;  1ZJR A;  3GYQ A;  3N4K A;  1IPA A;  3AXZ A;  4YQ6 A;  4YQC A;  4YQJ A;  4CNE A;  1MXI A;  3AIA A;  4IG6 A;  2Z0Y A;  2O3A A;  4YQ3 A;  5CO4 A;  3NK7 A;  4MCD A;  4YVH A;  4YQG A;  3N4J A;  1VHY A;  1VH0 A;  4L69 A;  5GM8 A;  4J3C A;  2QMM A;  3BBD A;  1X7O A;  5FAI A;  1GZ0 A;  4CNG A;  1UAJ A;  4YQL A;  5GMB A;  4PZK A;  1X7P A;  3KNU A;  4XBO A;  3KY7 A;  3OIN A;  3IEF A;  4MCC A;  4YPW A;  1NS5 A;  3NK6 A;  5GMC A;  1UAM A;  2HA8 A;  4X3L A;  4YQ5 A;  4KGN A;  2EGV A;  3L8U A;  3QUV A;  1Z85 A;  4YQB A;  3KW2 A;  4YPY A;  4YQ8 A;  4YPZ A;  4YVI A;  4YVG A;  4YPX A;  4YQN A;  2I6D A;  3DCM X;  1K3R A; 
#chains in the Genus database with same CATH topology
 4FMW A;  1OY5 A;  4YQQ A;  1UAL A;  4JAK A;  5D9F A;  4JWJ A;  4YQT A;  3OII A;  4YQ2 A;  1P9P A;  1TO0 A;  4YQ7 A;  4YQ9 A;  4H3Z A;  4YQR A;  4YQA A;  4YQO A;  3BBE A;  4JWG A;  2V3K A;  1O6D A;  4YVK A;  4H3Y A;  2YY8 A;  4YQI A;  3G1C A;  1VHK A;  4FAK A;  3SSX N;  4YQP A;  4KDZ A;  3KTY A;  4YVJ A;  2QWV A;  4YQS A;  3IC6 A;  2CX8 A;  4YQ1 A;  1UAK A;  3O7B A;  1TRR A;  4CNF A;  3ILK A;  1CO0 A;  3E5Y A;  4YQ0 A;  1NXZ A;  4YQD A;  1RCS A;  1V6Z A;  2V3J A;  3SSW N;  3ONP A;  3WRP A;  1MI7 R;  3OIJ A;  3KOR A;  1WRP R;  4RG1 A;  4X3M A;  2EGW A;  1J85 A;  1V2X A;  4JWH A;  3BBH A;  1WRS R;  4MCB A;  1TRO A;  4CND A;  3AI9 X;  4JAL A;  4YQK A;  4YQ4 A;  1ZT9 A;  4E8B A;  1ZJR A;  3GYQ A;  3N4K A;  1IPA A;  3AXZ A;  4YQ6 A;  4YQC A;  4YQJ A;  4CNE A;  1MXI A;  3AIA A;  4IG6 A;  2Z0Y A;  2O3A A;  4YQ3 A;  5CO4 A;  1WRT R;  3FRW A;  3NK7 A;  4MCD A;  4YVH A;  4YQG A;  3N4J A;  1VHY A;  1VH0 A;  4JWF A;  2XDI A;  4L69 A;  5GM8 A;  4J3C A;  2QMM A;  3BBD A;  1X7O A;  5FAI A;  1GZ0 A;  4CNG A;  1UAJ A;  4YQL A;  5GMB A;  4PZK A;  1X7P A;  3KNU A;  4XBO A;  3KY7 A;  3OIN A;  3IEF A;  4MCC A;  4YPW A;  2OZ9 R;  1NS5 A;  3NK6 A;  5GMC A;  1UAM A;  2HA8 A;  4X3L A;  4YQ5 A;  4KGN A;  2EGV A;  3L8U A;  3QUV A;  1Z85 A;  4YQB A;  3KW2 A;  4YPY A;  4YQ8 A;  1JHG A;  4YPZ A;  4YVI A;  4YVG A;  4YPX A;  4YQN A;  2I6D A;  3DCM X;  1K3R A; 
#chains in the Genus database with same CATH homology
 4FMW A;  1OY5 A;  4YQQ A;  1UAL A;  4JAK A;  5D9F A;  4JWJ A;  4YQT A;  3OII A;  4YQ2 A;  1P9P A;  1TO0 A;  4YQ7 A;  4YQ9 A;  4H3Z A;  4YQR A;  4YQA A;  4YQO A;  3BBE A;  4JWG A;  2V3K A;  1O6D A;  4YVK A;  4H3Y A;  2YY8 A;  4YQI A;  1VHK A;  4FAK A;  4YQP A;  4KDZ A;  3KTY A;  4YVJ A;  2QWV A;  4YQS A;  3IC6 A;  2CX8 A;  4YQ1 A;  1UAK A;  3O7B A;  4CNF A;  3ILK A;  3E5Y A;  4YQ0 A;  1NXZ A;  4YQD A;  1V6Z A;  2V3J A;  3ONP A;  3OIJ A;  4RG1 A;  4X3M A;  2EGW A;  1J85 A;  1V2X A;  4JWH A;  3BBH A;  4MCB A;  4CND A;  3AI9 X;  4JAL A;  4YQK A;  4YQ4 A;  4E8B A;  1ZJR A;  3GYQ A;  3N4K A;  1IPA A;  3AXZ A;  4YQ6 A;  4YQC A;  4YQJ A;  4CNE A;  1MXI A;  3AIA A;  4IG6 A;  2Z0Y A;  2O3A A;  4YQ3 A;  5CO4 A;  3NK7 A;  4MCD A;  4YVH A;  4YQG A;  3N4J A;  1VHY A;  1VH0 A;  4JWF A;  4L69 A;  5GM8 A;  4J3C A;  2QMM A;  3BBD A;  1X7O A;  5FAI A;  1GZ0 A;  4CNG A;  1UAJ A;  4YQL A;  5GMB A;  4PZK A;  1X7P A;  3KNU A;  4XBO A;  3KY7 A;  3OIN A;  3IEF A;  4MCC A;  4YPW A;  1NS5 A;  3NK6 A;  5GMC A;  1UAM A;  2HA8 A;  4X3L A;  4YQ5 A;  4KGN A;  2EGV A;  3L8U A;  3QUV A;  1Z85 A;  4YQB A;  3KW2 A;  4YPY A;  4YQ8 A;  4YPZ A;  4YVI A;  4YVG A;  4YPX A;  4YQN A;  2I6D A;  3DCM X;  1K3R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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