4H3YA

Crystal structure of an asymmetric dimer of a trna (guanine-(n(1)-)-methyltransferase from burkholderia phymatum bound to s-adenosyl homocystein in one half-site
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
Knots found
sequence length
255
structure length
255
Chain Sequence
SMQFDIVTLFPDMFRALTDWGITSRAAKQERYGLRTWNPRDFTTDNYRTIDDRPYGGGPGMVMLARPLEDAINAAKAAQAEQGIGGARVVMMSPQGATLNHDKVMRFAAEPGLILLCGRYEAIDQRLIDRVVDEEVSLGDFVLSGGELPAMALIDAVVRHLPGVLNDAQSAVQDSFVDGLLDCPHYTRPEEYDGVRVPDVLLGGHHAEIEQWRRREALRNTWLKRPDLIVQARKNKLLSRADEAWLASLAKDASK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
publication title Combining functional and structural genomics to sample the essential Burkholderia structome.
pubmed doi rcsb
source organism Burkholderia phymatum
total genus 77
structure length 255
sequence length 255
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2012-09-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4h3yA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4h3yA01
5GM8A 3ONPA 5D9FA 4KGNA 3O7BA 4YQJA 4YQ1A 3KY7A 4MCCA 2V3KA 4MCBA 3KNUA 3N4JA 1MXIA 1VHYA 4CNGA 4YVJA 4PZKA 4H3YA 1V2XA 1GZ0A 5GMBA 3E5YA 4X3MA 1O6DA 2EGVA 2QWVA 1UALA 4YPZA 4YQPA 3OINA 4KDZA 4IG6A 4YQIA 4CNFA 1IPAA 4YVIA 3KW2A 4L69A 5FAIA 4RG1A 1OY5A 4YQKA 1Z85A 4YVGA 2QMMA 4JALA 4YPYA 3NK7A 3L8UA 1K3RA 2YY8A 1UAJA 4YQ2A 3N4KA 4YQ4A 4YQ5A 4YQ3A 4YQRA 3BBHA 3IC6A 4YQCA 4FAKA 4YQ7A 4YQBA 1X7PA 1VHKA 1UAMA 4YQ9A 4YVKA 1J85A 2V3JA 1P9PA 3OIJA 4JAKA 1TO0A 3AIAA 4YQSA 1ZJRA 4YQTA 3AXZA 2O3AA 4YQGA 2HA8A 4YPWA 3GYQA 3DCMX 4H3ZA 4J3CA 4X3LA 2I6DA 4YPXA 4YQ8A 3OIIA 4MCDA 5CO4A 2CX8A 4YQOA 3AI9X 5GMCA 4CNDA 3QUVA 1X7OA 1VH0A 4E8BA 4YQDA 4YQLA 4YQNA 3KTYA 3BBDA 1NS5A 4YVHA 1NXZA 3IEFA 3BBEA 2EGWA 4YQAA 4YQQA 1UAKA 4YQ0A 2Z0YA 3NK6A 4XBOA 3ILKA 4YQ6A 4CNEA 1V6ZA
chains in the Genus database with same CATH superfamily
1JHGA 1MI7R 5GM8A 1TROA 3ONPA 5D9FA 4KGNA 3FRWA 3O7BA 4YQJA 4YQ1A 3KY7A 4MCCA 2V3KA 4MCBA 3KNUA 3N4JA 1MXIA 1RCSA 1VHYA 4CNGA 4YVJA 4PZKA 3KORA 4H3YA 1V2XA 1TRRA 1GZ0A 5GMBA 3E5YA 4X3MA 1O6DA 2EGVA 2QWVA 1UALA 4YPZA 4YQPA 3OINA 4KDZA 4IG6A 4YQIA 4CNFA 1IPAA 4YVIA 3KW2A 4L69A 5FAIA 4RG1A 1OY5A 4YQKA 1Z85A 4YVGA 1WRTR 2QMMA 4JALA 4YPYA 3NK7A 3L8UA 1K3RA 2YY8A 1UAJA 4YQ2A 3N4KA 4YQ4A 4YQ5A 4YQ3A 4YQRA 3G1CA 3BBHA 3IC6A 4YQCA 4FAKA 4YQ7A 4YQBA 1X7PA 1WRSR 1VHKA 1UAMA 3SSXN 4YQ9A 4YVKA 1J85A 2V3JA 1P9PA 3OIJA 4JAKA 1TO0A 3AIAA 4YQSA 1ZJRA 4YQTA 3AXZA 4JWGA 2O3AA 4YQGA 2HA8A 4YPWA 3GYQA 3DCMX 4H3ZA 4J3CA 4JWJA 4X3LA 2I6DA 4YPXA 4YQ8A 3OIIA 4MCDA 4FMWA 2CX8A 5CO4A 4YQOA 3AI9X 5GMCA 4CNDA 3QUVA 1X7OA 1VH0A 4E8BA 4JWFA 4YQDA 4YQLA 4YQNA 3KTYA 3BBDA 1NS5A 4YVHA 2XDIA 1NXZA 3IEFA 3BBEA 2EGWA 4YQAA 2OZ9R 3SSWN 3WRPA 1ZT9A 4YQQA 1UAKA 4YQ0A 4JWHA 2Z0YA 3NK6A 1CO0A 4XBOA 3ILKA 1WRPR 4YQ6A 4CNEA 1V6ZA
chains in the Genus database with same CATH topology
5GM8A 3ONPA 5D9FA 4KGNA 3O7BA 4YQJA 4YQ1A 3KY7A 4MCCA 2V3KA 4MCBA 3KNUA 3N4JA 1MXIA 1VHYA 4CNGA 4YVJA 4PZKA 4H3YA 1V2XA 1GZ0A 5GMBA 3E5YA 4X3MA 1O6DA 2EGVA 2QWVA 1UALA 4YPZA 4YQPA 3OINA 4KDZA 4IG6A 4YQIA 4CNFA 1IPAA 4YVIA 3KW2A 4L69A 5FAIA 4RG1A 1OY5A 4YQKA 1Z85A 4YVGA 2QMMA 4JALA 4YPYA 3NK7A 3L8UA 1K3RA 2YY8A 1UAJA 4YQ2A 3N4KA 4YQ4A 4YQ5A 4YQ3A 4YQRA 3BBHA 3IC6A 4YQCA 4FAKA 4YQ7A 4YQBA 1X7PA 1VHKA 1UAMA 4YQ9A 4YVKA 1J85A 2V3JA 1P9PA 3OIJA 4JAKA 1TO0A 3AIAA 4YQSA 1ZJRA 4YQTA 3AXZA 4JWGA 2O3AA 4YQGA 2HA8A 4YPWA 3GYQA 3DCMX 4H3ZA 4J3CA 4JWJA 4X3LA 2I6DA 4YPXA 4YQ8A 3OIIA 4MCDA 4FMWA 2CX8A 5CO4A 4YQOA 3AI9X 5GMCA 4CNDA 3QUVA 1X7OA 1VH0A 4E8BA 4JWFA 4YQDA 4YQLA 4YQNA 3KTYA 3BBDA 1NS5A 4YVHA 1NXZA 3IEFA 3BBEA 2EGWA 4YQAA 4YQQA 1UAKA 4YQ0A 4JWHA 2Z0YA 3NK6A 4XBOA 3ILKA 4YQ6A 4CNEA 1V6ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5GM8 A;  3ONP A;  5D9F A;  4KGN A;  3O7B A;  4YQJ A;  4YQ1 A;  3KY7 A;  4MCC A;  2V3K A;  4MCB A;  3KNU A;  3N4J A;  1MXI A;  1VHY A;  4CNG A;  4YVJ A;  4PZK A;  4H3Y A;  1V2X A;  1GZ0 A;  5GMB A;  3E5Y A;  4X3M A;  1O6D A;  2EGV A;  2QWV A;  1UAL A;  4YPZ A;  4YQP A;  3OIN A;  4KDZ A;  4IG6 A;  4YQI A;  4CNF A;  1IPA A;  4YVI A;  3KW2 A;  4L69 A;  5FAI A;  4RG1 A;  1OY5 A;  4YQK A;  1Z85 A;  4YVG A;  2QMM A;  4JAL A;  4YPY A;  3NK7 A;  3L8U A;  1K3R A;  2YY8 A;  1UAJ A;  4YQ2 A;  3N4K A;  4YQ4 A;  4YQ5 A;  4YQ3 A;  4YQR A;  3BBH A;  3IC6 A;  4YQC A;  4FAK A;  4YQ7 A;  4YQB A;  1X7P A;  1VHK A;  1UAM A;  4YQ9 A;  4YVK A;  1J85 A;  2V3J A;  1P9P A;  3OIJ A;  4JAK A;  1TO0 A;  3AIA A;  4YQS A;  1ZJR A;  4YQT A;  3AXZ A;  2O3A A;  4YQG A;  2HA8 A;  4YPW A;  3GYQ A;  3DCM X;  4H3Z A;  4J3C A;  4X3L A;  2I6D A;  4YPX A;  4YQ8 A;  3OII A;  4MCD A;  5CO4 A;  2CX8 A;  4YQO A;  3AI9 X;  5GMC A;  4CND A;  3QUV A;  1X7O A;  1VH0 A;  4E8B A;  4YQD A;  4YQL A;  4YQN A;  3KTY A;  3BBD A;  1NS5 A;  4YVH A;  1NXZ A;  3IEF A;  3BBE A;  2EGW A;  4YQA A;  4YQQ A;  1UAK A;  4YQ0 A;  2Z0Y A;  3NK6 A;  4XBO A;  3ILK A;  4YQ6 A;  4CNE A;  1V6Z A; 
#chains in the Genus database with same CATH topology
 1JHG A;  1MI7 R;  5GM8 A;  1TRO A;  3ONP A;  5D9F A;  4KGN A;  3FRW A;  3O7B A;  4YQJ A;  4YQ1 A;  3KY7 A;  4MCC A;  2V3K A;  4MCB A;  3KNU A;  3N4J A;  1MXI A;  1RCS A;  1VHY A;  4CNG A;  4YVJ A;  4PZK A;  3KOR A;  4H3Y A;  1V2X A;  1TRR A;  1GZ0 A;  5GMB A;  3E5Y A;  4X3M A;  1O6D A;  2EGV A;  2QWV A;  1UAL A;  4YPZ A;  4YQP A;  3OIN A;  4KDZ A;  4IG6 A;  4YQI A;  4CNF A;  1IPA A;  4YVI A;  3KW2 A;  4L69 A;  5FAI A;  4RG1 A;  1OY5 A;  4YQK A;  1Z85 A;  4YVG A;  1WRT R;  2QMM A;  4JAL A;  4YPY A;  3NK7 A;  3L8U A;  1K3R A;  2YY8 A;  1UAJ A;  4YQ2 A;  3N4K A;  4YQ4 A;  4YQ5 A;  4YQ3 A;  4YQR A;  3G1C A;  3BBH A;  3IC6 A;  4YQC A;  4FAK A;  4YQ7 A;  4YQB A;  1X7P A;  1WRS R;  1VHK A;  1UAM A;  3SSX N;  4YQ9 A;  4YVK A;  1J85 A;  2V3J A;  1P9P A;  3OIJ A;  4JAK A;  1TO0 A;  3AIA A;  4YQS A;  1ZJR A;  4YQT A;  3AXZ A;  4JWG A;  2O3A A;  4YQG A;  2HA8 A;  4YPW A;  3GYQ A;  3DCM X;  4H3Z A;  4J3C A;  4JWJ A;  4X3L A;  2I6D A;  4YPX A;  4YQ8 A;  3OII A;  4MCD A;  4FMW A;  2CX8 A;  5CO4 A;  4YQO A;  3AI9 X;  5GMC A;  4CND A;  3QUV A;  1X7O A;  1VH0 A;  4E8B A;  4JWF A;  4YQD A;  4YQL A;  4YQN A;  3KTY A;  3BBD A;  1NS5 A;  4YVH A;  2XDI A;  1NXZ A;  3IEF A;  3BBE A;  2EGW A;  4YQA A;  2OZ9 R;  3SSW N;  3WRP A;  1ZT9 A;  4YQQ A;  1UAK A;  4YQ0 A;  4JWH A;  2Z0Y A;  3NK6 A;  1CO0 A;  4XBO A;  3ILK A;  1WRP R;  4YQ6 A;  4CNE A;  1V6Z A; 
#chains in the Genus database with same CATH homology
 5GM8 A;  3ONP A;  5D9F A;  4KGN A;  3O7B A;  4YQJ A;  4YQ1 A;  3KY7 A;  4MCC A;  2V3K A;  4MCB A;  3KNU A;  3N4J A;  1MXI A;  1VHY A;  4CNG A;  4YVJ A;  4PZK A;  4H3Y A;  1V2X A;  1GZ0 A;  5GMB A;  3E5Y A;  4X3M A;  1O6D A;  2EGV A;  2QWV A;  1UAL A;  4YPZ A;  4YQP A;  3OIN A;  4KDZ A;  4IG6 A;  4YQI A;  4CNF A;  1IPA A;  4YVI A;  3KW2 A;  4L69 A;  5FAI A;  4RG1 A;  1OY5 A;  4YQK A;  1Z85 A;  4YVG A;  2QMM A;  4JAL A;  4YPY A;  3NK7 A;  3L8U A;  1K3R A;  2YY8 A;  1UAJ A;  4YQ2 A;  3N4K A;  4YQ4 A;  4YQ5 A;  4YQ3 A;  4YQR A;  3BBH A;  3IC6 A;  4YQC A;  4FAK A;  4YQ7 A;  4YQB A;  1X7P A;  1VHK A;  1UAM A;  4YQ9 A;  4YVK A;  1J85 A;  2V3J A;  1P9P A;  3OIJ A;  4JAK A;  1TO0 A;  3AIA A;  4YQS A;  1ZJR A;  4YQT A;  3AXZ A;  4JWG A;  2O3A A;  4YQG A;  2HA8 A;  4YPW A;  3GYQ A;  3DCM X;  4H3Z A;  4J3C A;  4JWJ A;  4X3L A;  2I6D A;  4YPX A;  4YQ8 A;  3OII A;  4MCD A;  4FMW A;  2CX8 A;  5CO4 A;  4YQO A;  3AI9 X;  5GMC A;  4CND A;  3QUV A;  1X7O A;  1VH0 A;  4E8B A;  4JWF A;  4YQD A;  4YQL A;  4YQN A;  3KTY A;  3BBD A;  1NS5 A;  4YVH A;  1NXZ A;  3IEF A;  3BBE A;  2EGW A;  4YQA A;  4YQQ A;  1UAK A;  4YQ0 A;  4JWH A;  2Z0Y A;  3NK6 A;  4XBO A;  3ILK A;  4YQ6 A;  4CNE A;  1V6Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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