3VG9A

Crystal structure of human adenosine a2a receptor with an allosteric inverse-agonist antibody at 2.7 a resolution
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
304
structure length
297
Chain Sequence
SSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
source organism Homo sapiens
publication title G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody
pubmed doi rcsb
molecule keywords Adenosine receptor A2a
total genus 105
structure length 297
sequence length 304
ec nomenclature
pdb deposition date 2011-08-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00001 7tm_1 7 transmembrane receptor (rhodopsin family)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1070.10 Mainly Alpha Up-down Bundle Rhopdopsin 7-helix transmembrane proteins Rhopdopsin 7-helix transmembrane proteins 3vg9A00
4FA7B 4BEZA 4EIYA 4G71B 3OE0A 2NTUA 3EH5B 3UONA 3QBIA 2ZFEA 3UTVA 2G87A 5G2DA 1DZEA 4BWBA 3VHZA 1KG9A 4PXFA 4TL3A 4JKVA 5C1MA 3EH3B 1JV6A 1IXFA 1TN0A 3REYA 5H2IA 1S52A 5AHZA 2ZZLA 4GP8B 3DDLA 4NC3A 3ODUA 1R84A 3QBLA 3UTWA 3X3CA 4BEYA 4GRVA 2JAGA 2Z73A 4MQTA 1KGBA 1EHKB 2WJKA 3AYMA 5ITEA 4LDEA 3X3BA 2L6XA 5BR2A 3OAXA 4DKLA 2I21A 3QAKA 1IW6A 1X0K1 2RH1A 2ZIYA 4GP5B 4GPOA 1Q5JA 2F95A 2Y02A 3KJ6A 3AYNA 2YCWA 5DHHA 4IARA 1O0AA 3UG9A 1AP9A 5G54A 1P8HA 4N4WA 2PEDA 5G36A 3HAPA 1C3WA 4FBZA 4EA3A 3NS0A 1JGJA 2QPDB 3VI0A 2I20A 4GYCA 3QDCA 5TGZA 4PXKA 5ETZA 1X0SA 5G28A 4QIDA 4MD1A 1GU8A 3MBVA 1S53A 4G7RB 5G2CA 3P0GA 4MQSA 5B6ZA 3NSBA 5B6XA 3A7KA 3S3DB 1VGOA 3CODA 1UCQA 1XIOA 3S8FB 2KSYA 5B6WA 2M3GA 3OE8A 3VVKA 2YCZA 3PXOA 3UZAA 2Y03A 5G2AA 3ZPQA 1C8RA 1HZXA 2I1XA 1F50A 4XT3A 3COCA 4JQ6A 3S3BB 3C9LA 1JFPA 5AX0A 1X0I1 3SN6R 1PXRA 4MD2A 2EI4A 3HAOA 4J4QA 4G72B 5EN0A 4UG2A 4IAQA 1S8JA 3QBGA 3QBKA 2KS9A 3V2YA 1KMEA 2YDOA 4UHRA 2VT4A 1XMEB 3BVDB 2BRDA 3HASA 4FPDA 4N4YB 3S3CB 1AT9A 3OE6A 5BR5A 4GP4B 5H2KA 4AMIA 3HARA 4WW3A 1R2NA 1MGYA 4Y9HA 3WQJA 3NY8A 4G7SB 5A44A 2YCXA 2NTWA 4G7QB 5G53A 5H2PA 5F8UA 1PY6A 1BM1A 1P8IA 3PQRA 3QJQB 3VG9A 2YCYA 5JJJA 2F93A 4OV0A 3PWHA 1U19A 1UAZA 2YDVA 2Y04A 3ABWA 4L6RA 5B6VA 1H2SA 5H2HA 1P8UA 2KSAA 1M0KA 5H2OA 2Z55A 4A4MA 1S51A 3AM6A 3ZPRA 5B0WA 4G70B 1S8LA 1FBBA 5FJGA 5AHYA 3NYAA 4L35A 3QJRB 3C9MA 1IW9A 1GUEA 3S8GB 1BRRA 5B35A 3DQBA 5AZDA 3QJSB 1E0PA 4KLYA 1QKOA 4BV0A 5JJNA 2X72A 1JV7A 4XTLA 2Y01A 4WAVA 3T45A 5ITCA 3QJTB 4EJ4A 5AX1A 4HWLA 1S54A 1BRDA 4K5YA 5LWEA 5H2NA 5B34A 1GZMA 4GBRA 2KSBA 4JR8A 4IB4A 3EH4B 4X31A 3D4SA 3OE9A 1F88A 4QRYA 4XT1A 1M0LA 3RFMA 4DAJA 5A45A 4XTNA 4LDOA 3PBLA 3UTYA 3PDSA 1F4ZA 5H2JA 5JJEA 5A8EA 1L9HA 5AWZA 5H2LA 4XXJA 1Q5IA 4BUOA 3HAQA 3UZCA 1H68A 3QAPA 5DYSA 3V2WA 5J7AA 3QJVB 1KG8A 2R4SA 1E12A 2AT9A 4HYXA 4HYJA 4QI1A 4BVNA 2I35A 1TN5A 3UTXA 1VJMA 4FAAB 4X1HA 2QPEB 5KKHA 1XJIA 2Y00A 3CAPA 1QKPA 1QM8A 2HPYA 2WJLA 1M0MA 1CWQA 4X32A 3QJUB 5B2NA 4MBSA 1BRXA 1LN6A 2R4RA 5B6YA 4KNFA 3VGAA 3ZEVA 4N6HA 1C8SA 3NY9A 1L0MA 2LNLA 3RZEA 4LDLA 3EMLA 1FBKA 1QHJA 3VW7A 4DJHA 5H2MA 1PXSA 3HANA 5DHGA 2J4YA 2JAFA 4AMJA 4XTOA
chains in the Genus database with same CATH superfamily
4FA7B 4BEZA 4EIYA 4G71B 3OE0A 2NTUA 3EH5B 3UONA 3QBIA 2ZFEA 3UTVA 2G87A 5G2DA 1DZEA 4BWBA 3VHZA 1KG9A 4PXFA 4TL3A 4JKVA 5C1MA 3EH3B 1JV6A 1IXFA 1TN0A 3REYA 5H2IA 1S52A 5AHZA 2ZZLA 4GP8B 3DDLA 4NC3A 3ODUA 1R84A 3QBLA 3UTWA 3X3CA 4BEYA 4GRVA 2JAGA 2Z73A 4MQTA 1KGBA 1EHKB 2WJKA 3AYMA 5ITEA 4LDEA 3X3BA 2L6XA 5BR2A 3OAXA 4DKLA 2I21A 3QAKA 1IW6A 1X0K1 2RH1A 2ZIYA 4GP5B 4GPOA 1Q5JA 2F95A 2Y02A 3KJ6A 3AYNA 2YCWA 5DHHA 4IARA 1O0AA 3UG9A 1AP9A 5G54A 1P8HA 4N4WA 2PEDA 5G36A 3HAPA 1C3WA 4FBZA 4EA3A 3NS0A 1JGJA 2QPDB 3VI0A 2I20A 4GYCA 3QDCA 5TGZA 4PXKA 5ETZA 1X0SA 5G28A 4QIDA 4MD1A 1GU8A 3MBVA 1S53A 4G7RB 5G2CA 3P0GA 4MQSA 5B6ZA 3NSBA 5B6XA 3A7KA 3S3DB 1VGOA 3CODA 1UCQA 1XIOA 3S8FB 2KSYA 5B6WA 2M3GA 3OE8A 3VVKA 2YCZA 3PXOA 3UZAA 2Y03A 5G2AA 3ZPQA 1C8RA 1HZXA 2I1XA 1F50A 4XT3A 3COCA 4JQ6A 3S3BB 3C9LA 1JFPA 5AX0A 1X0I1 3SN6R 1PXRA 4MD2A 2EI4A 3HAOA 4J4QA 4G72B 5EN0A 4UG2A 4IAQA 1S8JA 3QBGA 3QBKA 2KS9A 3V2YA 1KMEA 2YDOA 4UHRA 2VT4A 1XMEB 3BVDB 2BRDA 3HASA 4FPDA 4N4YB 3S3CB 1AT9A 3OE6A 5BR5A 4GP4B 5H2KA 4AMIA 3HARA 4WW3A 1R2NA 1MGYA 4Y9HA 3WQJA 3NY8A 4G7SB 5A44A 2YCXA 2NTWA 4G7QB 5G53A 5H2PA 5F8UA 1PY6A 1BM1A 1P8IA 3PQRA 3QJQB 3VG9A 2YCYA 5JJJA 2F93A 4OV0A 3PWHA 1U19A 1UAZA 2YDVA 2Y04A 3ABWA 4L6RA 5B6VA 1H2SA 5H2HA 1P8UA 2KSAA 1M0KA 5H2OA 2Z55A 4A4MA 1S51A 3AM6A 3ZPRA 5B0WA 4G70B 1S8LA 1FBBA 5FJGA 5AHYA 3NYAA 4L35A 3QJRB 3C9MA 1IW9A 1GUEA 3S8GB 1BRRA 5B35A 3DQBA 5AZDA 3QJSB 1E0PA 4KLYA 1QKOA 4BV0A 5JJNA 2X72A 1JV7A 4XTLA 2Y01A 4WAVA 3T45A 5ITCA 3QJTB 4EJ4A 5AX1A 4HWLA 1S54A 1BRDA 4K5YA 5LWEA 5H2NA 5B34A 1GZMA 4GBRA 2KSBA 4JR8A 4IB4A 4DS7E 3EH4B 4X31A 3D4SA 3OE9A 1F88A 4QRYA 4XT1A 1M0LA 3RFMA 4DAJA 5A45A 4XTNA 4LDOA 3PBLA 3UTYA 3PDSA 1F4ZA 5H2JA 5JJEA 5A8EA 1L9HA 5AWZA 5H2LA 4XXJA 1Q5IA 4BUOA 3HAQA 3UZCA 1H68A 3QAPA 5DYSA 3V2WA 5J7AA 3QJVB 1KG8A 2R4SA 1E12A 2AT9A 4HYXA 4HYJA 4QI1A 4BVNA 2I35A 1TN5A 3UTXA 1VJMA 4FAAB 4X1HA 2QPEB 5KKHA 1XJIA 2Y00A 3CAPA 1QKPA 1QM8A 2HPYA 2WJLA 1M0MA 1CWQA 4X32A 3QJUB 5B2NA 4MBSA 1BRXA 1LN6A 2R4RA 5B6YA 4KNFA 3VGAA 3ZEVA 4N6HA 1C8SA 3NY9A 1L0MA 2LNLA 3RZEA 4LDLA 3EMLA 1FBKA 1QHJA 3VW7A 4DJHA 5H2MA 1PXSA 3HANA 5DHGA 2J4YA 2JAFA 4AMJA 4XTOA
chains in the Genus database with same CATH topology
4FA7B 4BEZA 4EIYA 4G71B 3OE0A 2NTUA 3EH5B 3UONA 3QBIA 2ZFEA 3UTVA 2G87A 5G2DA 1DZEA 4BWBA 3VHZA 1KG9A 4PXFA 4TL3A 4JKVA 5C1MA 3EH3B 1JV6A 1IXFA 1TN0A 3REYA 5H2IA 1S52A 5AHZA 2ZZLA 4GP8B 3DDLA 4NC3A 3ODUA 1R84A 3QBLA 3UTWA 3X3CA 4BEYA 4GRVA 2JAGA 2Z73A 4MQTA 1KGBA 1EHKB 2WJKA 3AYMA 5ITEA 4LDEA 3X3BA 2L6XA 5BR2A 3OAXA 4DKLA 2I21A 3QAKA 1IW6A 1X0K1 2RH1A 2ZIYA 4GP5B 4GPOA 1Q5JA 2F95A 2Y02A 3KJ6A 3AYNA 2YCWA 5DHHA 4IARA 1O0AA 3UG9A 1AP9A 5G54A 1P8HA 4N4WA 2PEDA 5G36A 3HAPA 1C3WA 4FBZA 4EA3A 3NS0A 1JGJA 2QPDB 3VI0A 2I20A 4GYCA 3QDCA 5TGZA 4PXKA 5ETZA 1X0SA 5G28A 4QIDA 4MD1A 1GU8A 3MBVA 1S53A 4G7RB 5G2CA 3P0GA 4MQSA 5B6ZA 3NSBA 5B6XA 3A7KA 3S3DB 1VGOA 3CODA 1UCQA 1XIOA 3S8FB 2KSYA 5B6WA 2M3GA 3OE8A 3VVKA 2YCZA 3PXOA 3UZAA 2Y03A 5G2AA 3ZPQA 1C8RA 1HZXA 2I1XA 1F50A 4XT3A 3COCA 4JQ6A 3S3BB 3C9LA 1JFPA 5AX0A 1X0I1 3SN6R 1PXRA 4MD2A 2EI4A 3HAOA 4J4QA 4G72B 5EN0A 4UG2A 4IAQA 1S8JA 3QBGA 3QBKA 2KS9A 3V2YA 1KMEA 2YDOA 4UHRA 2VT4A 1XMEB 3BVDB 2BRDA 3HASA 4FPDA 4N4YB 3S3CB 1AT9A 3OE6A 5BR5A 4GP4B 5H2KA 4AMIA 3HARA 4WW3A 1R2NA 1MGYA 4Y9HA 3WQJA 3NY8A 4G7SB 5A44A 2YCXA 2NTWA 4G7QB 5G53A 5H2PA 5F8UA 1PY6A 1BM1A 1P8IA 3PQRA 3QJQB 3VG9A 2YCYA 5JJJA 2F93A 4OV0A 3PWHA 1U19A 1UAZA 2YDVA 2Y04A 3ABWA 4L6RA 5B6VA 1H2SA 5H2HA 1P8UA 2KSAA 1M0KA 5H2OA 2Z55A 4A4MA 1S51A 3AM6A 3ZPRA 5B0WA 4G70B 1S8LA 1FBBA 5FJGA 5AHYA 3NYAA 4L35A 3QJRB 3C9MA 1IW9A 1GUEA 3S8GB 1BRRA 5B35A 3DQBA 5AZDA 3QJSB 1E0PA 4KLYA 1QKOA 4BV0A 5JJNA 2X72A 1JV7A 4XTLA 2Y01A 4WAVA 3T45A 5ITCA 3QJTB 4EJ4A 5AX1A 4HWLA 1S54A 1BRDA 4K5YA 5LWEA 5H2NA 5B34A 1GZMA 4GBRA 2KSBA 4JR8A 4IB4A 4DS7E 3EH4B 4X31A 3D4SA 3OE9A 1F88A 4QRYA 4XT1A 1M0LA 3RFMA 4DAJA 5A45A 4XTNA 4LDOA 3PBLA 3UTYA 3PDSA 1F4ZA 5H2JA 5JJEA 5A8EA 1L9HA 5AWZA 5H2LA 4XXJA 1Q5IA 4BUOA 3HAQA 3UZCA 1H68A 3QAPA 5DYSA 3V2WA 5J7AA 3QJVB 1KG8A 2R4SA 1E12A 2AT9A 4HYXA 4HYJA 4QI1A 4BVNA 2I35A 1TN5A 3UTXA 1VJMA 4FAAB 4X1HA 2QPEB 5KKHA 1XJIA 2Y00A 3CAPA 1QKPA 1QM8A 2HPYA 2WJLA 1M0MA 1CWQA 4X32A 3QJUB 5B2NA 4MBSA 1BRXA 1LN6A 2R4RA 5B6YA 4KNFA 3VGAA 3ZEVA 4N6HA 1C8SA 3NY9A 1L0MA 2LNLA 3RZEA 4LDLA 3EMLA 1FBKA 1QHJA 3VW7A 4DJHA 5H2MA 1PXSA 3HANA 5DHGA 2J4YA 2JAFA 4AMJA 4XTOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FA7 B;  4BEZ A;  4EIY A;  4G71 B;  3OE0 A;  2NTU A;  3EH5 B;  3UON A;  3QBI A;  2ZFE A;  3UTV A;  2G87 A;  5G2D A;  1DZE A;  4BWB A;  3VHZ A;  1KG9 A;  4PXF A;  4TL3 A;  4JKV A;  5C1M A;  3EH3 B;  1JV6 A;  1IXF A;  1TN0 A;  3REY A;  5H2I A;  1S52 A;  5AHZ A;  2ZZL A;  4GP8 B;  3DDL A;  4NC3 A;  3ODU A;  1R84 A;  3QBL A;  3UTW A;  3X3C A;  4BEY A;  4GRV A;  2JAG A;  2Z73 A;  4MQT A;  1KGB A;  1EHK B;  2WJK A;  3AYM A;  5ITE A;  4LDE A;  3X3B A;  2L6X A;  5BR2 A;  3OAX A;  4DKL A;  2I21 A;  3QAK A;  1IW6 A;  1X0K 1;  2RH1 A;  2ZIY A;  4GP5 B;  4GPO A;  1Q5J A;  2F95 A;  2Y02 A;  3KJ6 A;  3AYN A;  2YCW A;  5DHH A;  4IAR A;  1O0A A;  3UG9 A;  1AP9 A;  5G54 A;  1P8H A;  4N4W A;  2PED A;  5G36 A;  3HAP A;  1C3W A;  4FBZ A;  4EA3 A;  3NS0 A;  1JGJ A;  2QPD B;  3VI0 A;  2I20 A;  4GYC A;  3QDC A;  5TGZ A;  4PXK A;  5ETZ A;  1X0S A;  5G28 A;  4QID A;  4MD1 A;  1GU8 A;  3MBV A;  1S53 A;  4G7R B;  5G2C A;  3P0G A;  4MQS A;  5B6Z A;  3NSB A;  5B6X A;  3A7K A;  3S3D B;  1VGO A;  3COD A;  1UCQ A;  1XIO A;  3S8F B;  2KSY A;  5B6W A;  2M3G A;  3OE8 A;  3VVK A;  2YCZ A;  3PXO A;  3UZA A;  2Y03 A;  5G2A A;  3ZPQ A;  1C8R A;  1HZX A;  2I1X A;  1F50 A;  4XT3 A;  3COC A;  4JQ6 A;  3S3B B;  3C9L A;  1JFP A;  5AX0 A;  1X0I 1;  3SN6 R;  1PXR A;  4MD2 A;  2EI4 A;  3HAO A;  4J4Q A;  4G72 B;  5EN0 A;  4UG2 A;  4IAQ A;  1S8J A;  3QBG A;  3QBK A;  2KS9 A;  3V2Y A;  1KME A;  2YDO A;  4UHR A;  2VT4 A;  1XME B;  3BVD B;  2BRD A;  3HAS A;  4FPD A;  4N4Y B;  3S3C B;  1AT9 A;  3OE6 A;  5BR5 A;  4GP4 B;  5H2K A;  4AMI A;  3HAR A;  4WW3 A;  1R2N A;  1MGY A;  4Y9H A;  3WQJ A;  3NY8 A;  4G7S B;  5A44 A;  2YCX A;  2NTW A;  4G7Q B;  5G53 A;  5H2P A;  5F8U A;  1PY6 A;  1BM1 A;  1P8I A;  3PQR A;  3QJQ B;  3VG9 A;  2YCY A;  5JJJ A;  2F93 A;  4OV0 A;  3PWH A;  1U19 A;  1UAZ A;  2YDV A;  2Y04 A;  3ABW A;  4L6R A;  5B6V A;  1H2S A;  5H2H A;  1P8U A;  2KSA A;  1M0K A;  5H2O A;  2Z55 A;  4A4M A;  1S51 A;  3AM6 A;  3ZPR A;  5B0W A;  4G70 B;  1S8L A;  1FBB A;  5FJG A;  5AHY A;  3NYA A;  4L35 A;  3QJR B;  3C9M A;  1IW9 A;  1GUE A;  3S8G B;  1BRR A;  5B35 A;  3DQB A;  5AZD A;  3QJS B;  1E0P A;  4KLY A;  1QKO A;  4BV0 A;  5JJN A;  2X72 A;  1JV7 A;  4XTL A;  2Y01 A;  4WAV A;  3T45 A;  5ITC A;  3QJT B;  4EJ4 A;  5AX1 A;  4HWL A;  1S54 A;  1BRD A;  4K5Y A;  5LWE A;  5H2N A;  5B34 A;  1GZM A;  4GBR A;  2KSB A;  4JR8 A;  4IB4 A;  3EH4 B;  4X31 A;  3D4S A;  3OE9 A;  1F88 A;  4QRY A;  4XT1 A;  1M0L A;  3RFM A;  4DAJ A;  5A45 A;  4XTN A;  4LDO A;  3PBL A;  3UTY A;  3PDS A;  1F4Z A;  5H2J A;  5JJE A;  5A8E A;  1L9H A;  5AWZ A;  5H2L A;  4XXJ A;  1Q5I A;  4BUO A;  3HAQ A;  3UZC A;  1H68 A;  3QAP A;  5DYS A;  3V2W A;  5J7A A;  3QJV B;  1KG8 A;  2R4S A;  1E12 A;  2AT9 A;  4HYX A;  4HYJ A;  4QI1 A;  4BVN A;  2I35 A;  1TN5 A;  3UTX A;  1VJM A;  4FAA B;  4X1H A;  2QPE B;  5KKH A;  1XJI A;  2Y00 A;  3CAP A;  1QKP A;  1QM8 A;  2HPY A;  2WJL A;  1M0M A;  1CWQ A;  4X32 A;  3QJU B;  5B2N A;  4MBS A;  1BRX A;  1LN6 A;  2R4R A;  5B6Y A;  4KNF A;  3VGA A;  3ZEV A;  4N6H A;  1C8S A;  3NY9 A;  1L0M A;  2LNL A;  3RZE A;  4LDL A;  3EML A;  1FBK A;  1QHJ A;  3VW7 A;  4DJH A;  5H2M A;  1PXS A;  3HAN A;  5DHG A;  2J4Y A;  2JAF A;  4AMJ A;  4XTO A; 
#chains in the Genus database with same CATH topology
 4FA7 B;  4BEZ A;  4EIY A;  4G71 B;  3OE0 A;  2NTU A;  3EH5 B;  3UON A;  3QBI A;  2ZFE A;  3UTV A;  2G87 A;  5G2D A;  1DZE A;  4BWB A;  3VHZ A;  1KG9 A;  4PXF A;  4TL3 A;  4JKV A;  5C1M A;  3EH3 B;  1JV6 A;  1IXF A;  1TN0 A;  3REY A;  5H2I A;  1S52 A;  5AHZ A;  2ZZL A;  4GP8 B;  3DDL A;  4NC3 A;  3ODU A;  1R84 A;  3QBL A;  3UTW A;  3X3C A;  4BEY A;  4GRV A;  2JAG A;  2Z73 A;  4MQT A;  1KGB A;  1EHK B;  2WJK A;  3AYM A;  5ITE A;  4LDE A;  3X3B A;  2L6X A;  5BR2 A;  3OAX A;  4DKL A;  2I21 A;  3QAK A;  1IW6 A;  1X0K 1;  2RH1 A;  2ZIY A;  4GP5 B;  4GPO A;  1Q5J A;  2F95 A;  2Y02 A;  3KJ6 A;  3AYN A;  2YCW A;  5DHH A;  4IAR A;  1O0A A;  3UG9 A;  1AP9 A;  5G54 A;  1P8H A;  4N4W A;  2PED A;  5G36 A;  3HAP A;  1C3W A;  4FBZ A;  4EA3 A;  3NS0 A;  1JGJ A;  2QPD B;  3VI0 A;  2I20 A;  4GYC A;  3QDC A;  5TGZ A;  4PXK A;  5ETZ A;  1X0S A;  5G28 A;  4QID A;  4MD1 A;  1GU8 A;  3MBV A;  1S53 A;  4G7R B;  5G2C A;  3P0G A;  4MQS A;  5B6Z A;  3NSB A;  5B6X A;  3A7K A;  3S3D B;  1VGO A;  3COD A;  1UCQ A;  1XIO A;  3S8F B;  2KSY A;  5B6W A;  2M3G A;  3OE8 A;  3VVK A;  2YCZ A;  3PXO A;  3UZA A;  2Y03 A;  5G2A A;  3ZPQ A;  1C8R A;  1HZX A;  2I1X A;  1F50 A;  4XT3 A;  3COC A;  4JQ6 A;  3S3B B;  3C9L A;  1JFP A;  5AX0 A;  1X0I 1;  3SN6 R;  1PXR A;  4MD2 A;  2EI4 A;  3HAO A;  4J4Q A;  4G72 B;  5EN0 A;  4UG2 A;  4IAQ A;  1S8J A;  3QBG A;  3QBK A;  2KS9 A;  3V2Y A;  1KME A;  2YDO A;  4UHR A;  2VT4 A;  1XME B;  3BVD B;  2BRD A;  3HAS A;  4FPD A;  4N4Y B;  3S3C B;  1AT9 A;  3OE6 A;  5BR5 A;  4GP4 B;  5H2K A;  4AMI A;  3HAR A;  4WW3 A;  1R2N A;  1MGY A;  4Y9H A;  3WQJ A;  3NY8 A;  4G7S B;  5A44 A;  2YCX A;  2NTW A;  4G7Q B;  5G53 A;  5H2P A;  5F8U A;  1PY6 A;  1BM1 A;  1P8I A;  3PQR A;  3QJQ B;  3VG9 A;  2YCY A;  5JJJ A;  2F93 A;  4OV0 A;  3PWH A;  1U19 A;  1UAZ A;  2YDV A;  2Y04 A;  3ABW A;  4L6R A;  5B6V A;  1H2S A;  5H2H A;  1P8U A;  2KSA A;  1M0K A;  5H2O A;  2Z55 A;  4A4M A;  1S51 A;  3AM6 A;  3ZPR A;  5B0W A;  4G70 B;  1S8L A;  1FBB A;  5FJG A;  5AHY A;  3NYA A;  4L35 A;  3QJR B;  3C9M A;  1IW9 A;  1GUE A;  3S8G B;  1BRR A;  5B35 A;  3DQB A;  5AZD A;  3QJS B;  1E0P A;  4KLY A;  1QKO A;  4BV0 A;  5JJN A;  2X72 A;  1JV7 A;  4XTL A;  2Y01 A;  4WAV A;  3T45 A;  5ITC A;  3QJT B;  4EJ4 A;  5AX1 A;  4HWL A;  1S54 A;  1BRD A;  4K5Y A;  5LWE A;  5H2N A;  5B34 A;  1GZM A;  4GBR A;  2KSB A;  4JR8 A;  4IB4 A;  4DS7 E;  3EH4 B;  4X31 A;  3D4S A;  3OE9 A;  1F88 A;  4QRY A;  4XT1 A;  1M0L A;  3RFM A;  4DAJ A;  5A45 A;  4XTN A;  4LDO A;  3PBL A;  3UTY A;  3PDS A;  1F4Z A;  5H2J A;  5JJE A;  5A8E A;  1L9H A;  5AWZ A;  5H2L A;  4XXJ A;  1Q5I A;  4BUO A;  3HAQ A;  3UZC A;  1H68 A;  3QAP A;  5DYS A;  3V2W A;  5J7A A;  3QJV B;  1KG8 A;  2R4S A;  1E12 A;  2AT9 A;  4HYX A;  4HYJ A;  4QI1 A;  4BVN A;  2I35 A;  1TN5 A;  3UTX A;  1VJM A;  4FAA B;  4X1H A;  2QPE B;  5KKH A;  1XJI A;  2Y00 A;  3CAP A;  1QKP A;  1QM8 A;  2HPY A;  2WJL A;  1M0M A;  1CWQ A;  4X32 A;  3QJU B;  5B2N A;  4MBS A;  1BRX A;  1LN6 A;  2R4R A;  5B6Y A;  4KNF A;  3VGA A;  3ZEV A;  4N6H A;  1C8S A;  3NY9 A;  1L0M A;  2LNL A;  3RZE A;  4LDL A;  3EML A;  1FBK A;  1QHJ A;  3VW7 A;  4DJH A;  5H2M A;  1PXS A;  3HAN A;  5DHG A;  2J4Y A;  2JAF A;  4AMJ A;  4XTO A; 
#chains in the Genus database with same CATH homology
 4FA7 B;  4BEZ A;  4EIY A;  4G71 B;  3OE0 A;  2NTU A;  3EH5 B;  3UON A;  3QBI A;  2ZFE A;  3UTV A;  2G87 A;  5G2D A;  1DZE A;  4BWB A;  3VHZ A;  1KG9 A;  4PXF A;  4TL3 A;  4JKV A;  5C1M A;  3EH3 B;  1JV6 A;  1IXF A;  1TN0 A;  3REY A;  5H2I A;  1S52 A;  5AHZ A;  2ZZL A;  4GP8 B;  3DDL A;  4NC3 A;  3ODU A;  1R84 A;  3QBL A;  3UTW A;  3X3C A;  4BEY A;  4GRV A;  2JAG A;  2Z73 A;  4MQT A;  1KGB A;  1EHK B;  2WJK A;  3AYM A;  5ITE A;  4LDE A;  3X3B A;  2L6X A;  5BR2 A;  3OAX A;  4DKL A;  2I21 A;  3QAK A;  1IW6 A;  1X0K 1;  2RH1 A;  2ZIY A;  4GP5 B;  4GPO A;  1Q5J A;  2F95 A;  2Y02 A;  3KJ6 A;  3AYN A;  2YCW A;  5DHH A;  4IAR A;  1O0A A;  3UG9 A;  1AP9 A;  5G54 A;  1P8H A;  4N4W A;  2PED A;  5G36 A;  3HAP A;  1C3W A;  4FBZ A;  4EA3 A;  3NS0 A;  1JGJ A;  2QPD B;  3VI0 A;  2I20 A;  4GYC A;  3QDC A;  5TGZ A;  4PXK A;  5ETZ A;  1X0S A;  5G28 A;  4QID A;  4MD1 A;  1GU8 A;  3MBV A;  1S53 A;  4G7R B;  5G2C A;  3P0G A;  4MQS A;  5B6Z A;  3NSB A;  5B6X A;  3A7K A;  3S3D B;  1VGO A;  3COD A;  1UCQ A;  1XIO A;  3S8F B;  2KSY A;  5B6W A;  2M3G A;  3OE8 A;  3VVK A;  2YCZ A;  3PXO A;  3UZA A;  2Y03 A;  5G2A A;  3ZPQ A;  1C8R A;  1HZX A;  2I1X A;  1F50 A;  4XT3 A;  3COC A;  4JQ6 A;  3S3B B;  3C9L A;  1JFP A;  5AX0 A;  1X0I 1;  3SN6 R;  1PXR A;  4MD2 A;  2EI4 A;  3HAO A;  4J4Q A;  4G72 B;  5EN0 A;  4UG2 A;  4IAQ A;  1S8J A;  3QBG A;  3QBK A;  2KS9 A;  3V2Y A;  1KME A;  2YDO A;  4UHR A;  2VT4 A;  1XME B;  3BVD B;  2BRD A;  3HAS A;  4FPD A;  4N4Y B;  3S3C B;  1AT9 A;  3OE6 A;  5BR5 A;  4GP4 B;  5H2K A;  4AMI A;  3HAR A;  4WW3 A;  1R2N A;  1MGY A;  4Y9H A;  3WQJ A;  3NY8 A;  4G7S B;  5A44 A;  2YCX A;  2NTW A;  4G7Q B;  5G53 A;  5H2P A;  5F8U A;  1PY6 A;  1BM1 A;  1P8I A;  3PQR A;  3QJQ B;  3VG9 A;  2YCY A;  5JJJ A;  2F93 A;  4OV0 A;  3PWH A;  1U19 A;  1UAZ A;  2YDV A;  2Y04 A;  3ABW A;  4L6R A;  5B6V A;  1H2S A;  5H2H A;  1P8U A;  2KSA A;  1M0K A;  5H2O A;  2Z55 A;  4A4M A;  1S51 A;  3AM6 A;  3ZPR A;  5B0W A;  4G70 B;  1S8L A;  1FBB A;  5FJG A;  5AHY A;  3NYA A;  4L35 A;  3QJR B;  3C9M A;  1IW9 A;  1GUE A;  3S8G B;  1BRR A;  5B35 A;  3DQB A;  5AZD A;  3QJS B;  1E0P A;  4KLY A;  1QKO A;  4BV0 A;  5JJN A;  2X72 A;  1JV7 A;  4XTL A;  2Y01 A;  4WAV A;  3T45 A;  5ITC A;  3QJT B;  4EJ4 A;  5AX1 A;  4HWL A;  1S54 A;  1BRD A;  4K5Y A;  5LWE A;  5H2N A;  5B34 A;  1GZM A;  4GBR A;  2KSB A;  4JR8 A;  4IB4 A;  4DS7 E;  3EH4 B;  4X31 A;  3D4S A;  3OE9 A;  1F88 A;  4QRY A;  4XT1 A;  1M0L A;  3RFM A;  4DAJ A;  5A45 A;  4XTN A;  4LDO A;  3PBL A;  3UTY A;  3PDS A;  1F4Z A;  5H2J A;  5JJE A;  5A8E A;  1L9H A;  5AWZ A;  5H2L A;  4XXJ A;  1Q5I A;  4BUO A;  3HAQ A;  3UZC A;  1H68 A;  3QAP A;  5DYS A;  3V2W A;  5J7A A;  3QJV B;  1KG8 A;  2R4S A;  1E12 A;  2AT9 A;  4HYX A;  4HYJ A;  4QI1 A;  4BVN A;  2I35 A;  1TN5 A;  3UTX A;  1VJM A;  4FAA B;  4X1H A;  2QPE B;  5KKH A;  1XJI A;  2Y00 A;  3CAP A;  1QKP A;  1QM8 A;  2HPY A;  2WJL A;  1M0M A;  1CWQ A;  4X32 A;  3QJU B;  5B2N A;  4MBS A;  1BRX A;  1LN6 A;  2R4R A;  5B6Y A;  4KNF A;  3VGA A;  3ZEV A;  4N6H A;  1C8S A;  3NY9 A;  1L0M A;  2LNL A;  3RZE A;  4LDL A;  3EML A;  1FBK A;  1QHJ A;  3VW7 A;  4DJH A;  5H2M A;  1PXS A;  3HAN A;  5DHG A;  2J4Y A;  2JAF A;  4AMJ A;  4XTO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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