3W8HB

Crystal structure of ccm3 in complex with the c-terminal regulatory domain of stk25
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
66
structure length
66
Chain Sequence
EFSQCLSTLVRPVFGELKEKHKQSGGSVGALEELENAFSLAEESCPGISDKLMVHLVERVQRFSHN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Protein binding/transferase
source organism Homo sapiens
publication title Structural Basis for the Unique Heterodimeric Assembly between Cerebral Cavernous Malformation 3 and Germinal Center Kinase III.
pubmed doi rcsb
molecule keywords Programmed cell death protein 10
total genus 24
structure length 66
sequence length 66
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2013-03-13
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.12.70 Mainly Alpha Orthogonal Bundle Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 3w8hB00
3AJMA 3L8JA 3L8IA 3RQGA 4GEHB 3W8IB 3RQFA 3RQEA 3W8HB
chains in the Genus database with same CATH superfamily
3QK8A 3AM1A 4K3WA 3HINA 3I47A 4I4ZA 4JYLA 4U18A 3T89A 4EMLA 4FZWC 4ELSA 3R9TA 3L8IA 3H02A 3Q1TA 1MJ3A 1EF8A 4MOUA 1NZYA 2FBMA 3IRBA 3L8JA 5KJPA 3O4XE 3ADCA 3RSIA 3AJMA 3T8AA 1UX4A 3QXIA 4WCZA 5JBXA 4JFCA 4OLQA 5C9GA 4NEKA 3HRXA 2UZFA 3P5MA 4MI2A 4IZCA 3Q0JA 4I42A 1EY3A 3G64A 1UIYA 2F6QA 2P63A 3MOYA 3T88A 1Q51A 1DUBA 4U19A 4QIIA 4QIJA 2DUBA 3RQFA 1EF9A 5JBWA 1HZDA 3ADDA 1RJNA 3R9SA 1DCIA 3SWXA 4ZU2A 4JOTA 4ELXA 1Q52A 3RQEA 3SLLA 2GTRA 3ADBA 3A4NA 3RQGA 4ELWA 3W8IB 3TLFA 2HW5A 2FW2A 4IZBA 4KNPA 2PBPA 2IEXA 3A4LA 4JWVA 3MYBA 2EJ5A 2VX2A 1UX5A 4NNQA 2ZQRA 3H81A 4I52A 3A4MA 3Q0GA 4JCSA 4K2NA 1WZ8A 2ZQQA 1RJMA 2PPYA 4U1AA 1Y64B 3TRRA 2VREA 2QQ3A 4F47A 3KQFA 4GEHB 4IZDA 3FDUA 3OC7A 4OG1A 1JXZA 3QXZA 4FZWA 3PZKA 3R0OA 3W8HB 1NZYB 4FJWD
chains in the Genus database with same CATH topology
3AM1A 1RJMA 3RQEA 3ADBA 1Y64B 3L8IA 3A4NA 2P63A 3RQGA 3W8IB 3IRBA 3L8JA 4GEHB 3RQFA 3A4LA 3O4XE 3ADCA 3AJMA 1UX4A 1UX5A 3ADDA 4NNQA 3W8HB 3A4MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AJM A;  3L8J A;  3L8I A;  3RQG A;  4GEH B;  3W8I B;  3RQF A;  3RQE A;  3W8H B; 
#chains in the Genus database with same CATH topology
 3QK8 A;  3AM1 A;  4K3W A;  3HIN A;  3I47 A;  4I4Z A;  4JYL A;  4U18 A;  3T89 A;  4EML A;  4FZW C;  4ELS A;  3R9T A;  3L8I A;  3H02 A;  3Q1T A;  1MJ3 A;  1EF8 A;  4MOU A;  1NZY A;  2FBM A;  3IRB A;  3L8J A;  5KJP A;  3O4X E;  3ADC A;  3RSI A;  3AJM A;  3T8A A;  1UX4 A;  3QXI A;  4WCZ A;  5JBX A;  4JFC A;  4OLQ A;  5C9G A;  4NEK A;  3HRX A;  2UZF A;  3P5M A;  4MI2 A;  4IZC A;  3Q0J A;  4I42 A;  1EY3 A;  3G64 A;  1UIY A;  2F6Q A;  2P63 A;  3MOY A;  3T88 A;  1Q51 A;  1DUB A;  4U19 A;  4QII A;  4QIJ A;  2DUB A;  3RQF A;  1EF9 A;  5JBW A;  1HZD A;  3ADD A;  1RJN A;  3R9S A;  1DCI A;  3SWX A;  4ZU2 A;  4JOT A;  4ELX A;  1Q52 A;  3RQE A;  3SLL A;  2GTR A;  3ADB A;  3A4N A;  3RQG A;  4ELW A;  3W8I B;  3TLF A;  2HW5 A;  2FW2 A;  4IZB A;  4KNP A;  2PBP A;  2IEX A;  3A4L A;  4JWV A;  3MYB A;  2EJ5 A;  2VX2 A;  1UX5 A;  4NNQ A;  2ZQR A;  3H81 A;  4I52 A;  3A4M A;  3Q0G A;  4JCS A;  4K2N A;  1WZ8 A;  2ZQQ A;  1RJM A;  2PPY A;  4U1A A;  1Y64 B;  3TRR A;  2VRE A;  2QQ3 A;  4F47 A;  3KQF A;  4GEH B;  4IZD A;  3FDU A;  3OC7 A;  4OG1 A;  1JXZ A;  3QXZ A;  4FZW A;  3PZK A;  3R0O A;  3W8H B;  1NZY B;  4FJW D; 
#chains in the Genus database with same CATH homology
 3AM1 A;  1RJM A;  3RQE A;  3ADB A;  1Y64 B;  3L8I A;  3A4N A;  2P63 A;  3RQG A;  3W8I B;  3IRB A;  3L8J A;  4GEH B;  3RQF A;  3A4L A;  3O4X E;  3ADC A;  3AJM A;  1UX4 A;  1UX5 A;  3ADD A;  4NNQ A;  3W8H B;  3A4M A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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