3W8IB

Crystal structure of ccm3 in complex with the c-terminal regulatory domain of mst4
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
67
structure length
67
Chain Sequence
PGSMLVQTLSCLSMIITPAFAELKQQDENNASRNQAIEELEKSIAVAEAACPGITDKMVKKLIEKFQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis for the Unique Heterodimeric Assembly between Cerebral Cavernous Malformation 3 and Germinal Center Kinase III.
pubmed doi rcsb
molecule tags Protein binding/transferase
source organism Homo sapiens
molecule keywords Programmed cell death protein 10
total genus 29
structure length 67
sequence length 67
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2013-03-13
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.12.70 Mainly Alpha Orthogonal Bundle Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 3w8iB00
3W8HB 3AJMA 4GEHB 3RQGA 3L8JA 3RQEA 3W8IB 3L8IA 3RQFA
chains in the Genus database with same CATH superfamily
3RSIA 1RJMA 3OC7A 1UIYA 5JBWA 3W8IB 4U18A 3R9TA 5JBXA 4F47A 1NZYB 3QXIA 3R0OA 5C9GA 4JFCA 4FZWC 3A4LA 3SLLA 3T89A 2PBPA 3H02A 2ZQRA 4EMLA 3O4XE 1EY3A 4OG1A 3HRXA 4U19A 4ELSA 1UX5A 3SWXA 2HW5A 1EF8A 3R9SA 4I4ZA 4QIJA 1JXZA 4I52A 3TRRA 1Y64B 3G64A 3T88A 3A4NA 3T8AA 4OLQA 4FZWA 3I47A 3Q0JA 4K3WA 3MOYA 4IZDA 2VREA 2QQ3A 4NNQA 4ZU2A 4JWVA 3QK8A 1Q51A 4KNPA 3L8IA 1DCIA 4FJWD 3W8HB 3TLFA 2PPYA 4MOUA 3RQEA 4WCZA 5KJPA 1RJNA 3HINA 3KQFA 2P63A 2FW2A 4NEKA 4JYLA 1MJ3A 3FDUA 4IZCA 3AM1A 3RQFA 1UX4A 1NZYA 3ADDA 2DUBA 2FBMA 4GEHB 3RQGA 2ZQQA 1HZDA 3IRBA 3AJMA 2UZFA 3ADBA 1EF9A 4K2NA 3Q1TA 3L8JA 3P5MA 4U1AA 2EJ5A 4JCSA 4IZBA 3Q0GA 3MYBA 3ADCA 4ELXA 1Q52A 3PZKA 3QXZA 3H81A 4MI2A 4QIIA 2F6QA 3A4MA 1WZ8A 4I42A 2IEXA 4JOTA 2VX2A 4ELWA 2GTRA 1DUBA
chains in the Genus database with same CATH topology
3W8HB 1UX5A 3ADBA 1RJMA 3L8JA 3RQEA 3W8IB 1Y64B 3A4NA 2P63A 3ADCA 3A4LA 3AM1A 3A4MA 3RQFA 1UX4A 3ADDA 4GEHB 4NNQA 3RQGA 3O4XE 3L8IA 3IRBA 3AJMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3W8H B;  3AJM A;  4GEH B;  3RQG A;  3L8J A;  3RQE A;  3W8I B;  3L8I A;  3RQF A; 
#chains in the Genus database with same CATH topology
 3RSI A;  1RJM A;  3OC7 A;  1UIY A;  5JBW A;  3W8I B;  4U18 A;  3R9T A;  5JBX A;  4F47 A;  1NZY B;  3QXI A;  3R0O A;  5C9G A;  4JFC A;  4FZW C;  3A4L A;  3SLL A;  3T89 A;  2PBP A;  3H02 A;  2ZQR A;  4EML A;  3O4X E;  1EY3 A;  4OG1 A;  3HRX A;  4U19 A;  4ELS A;  1UX5 A;  3SWX A;  2HW5 A;  1EF8 A;  3R9S A;  4I4Z A;  4QIJ A;  1JXZ A;  4I52 A;  3TRR A;  1Y64 B;  3G64 A;  3T88 A;  3A4N A;  3T8A A;  4OLQ A;  4FZW A;  3I47 A;  3Q0J A;  4K3W A;  3MOY A;  4IZD A;  2VRE A;  2QQ3 A;  4NNQ A;  4ZU2 A;  4JWV A;  3QK8 A;  1Q51 A;  4KNP A;  3L8I A;  1DCI A;  4FJW D;  3W8H B;  3TLF A;  2PPY A;  4MOU A;  3RQE A;  4WCZ A;  5KJP A;  1RJN A;  3HIN A;  3KQF A;  2P63 A;  2FW2 A;  4NEK A;  4JYL A;  1MJ3 A;  3FDU A;  4IZC A;  3AM1 A;  3RQF A;  1UX4 A;  1NZY A;  3ADD A;  2DUB A;  2FBM A;  4GEH B;  3RQG A;  2ZQQ A;  1HZD A;  3IRB A;  3AJM A;  2UZF A;  3ADB A;  1EF9 A;  4K2N A;  3Q1T A;  3L8J A;  3P5M A;  4U1A A;  2EJ5 A;  4JCS A;  4IZB A;  3Q0G A;  3MYB A;  3ADC A;  4ELX A;  1Q52 A;  3PZK A;  3QXZ A;  3H81 A;  4MI2 A;  4QII A;  2F6Q A;  3A4M A;  1WZ8 A;  4I42 A;  2IEX A;  4JOT A;  2VX2 A;  4ELW A;  2GTR A;  1DUB A; 
#chains in the Genus database with same CATH homology
 3W8H B;  1UX5 A;  3ADB A;  1RJM A;  3L8J A;  3RQE A;  3W8I B;  1Y64 B;  3A4N A;  2P63 A;  3ADC A;  3A4L A;  3AM1 A;  3A4M A;  3RQF A;  1UX4 A;  3ADD A;  4GEH B;  4NNQ A;  3RQG A;  3O4X E;  3L8I A;  3IRB A;  3AJM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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