3W8IB

Crystal structure of ccm3 in complex with the c-terminal regulatory domain of mst4
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
67
structure length
67
Chain Sequence
PGSMLVQTLSCLSMIITPAFAELKQQDENNASRNQAIEELEKSIAVAEAACPGITDKMVKKLIEKFQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis for the Unique Heterodimeric Assembly between Cerebral Cavernous Malformation 3 and Germinal Center Kinase III.
pubmed doi rcsb
molecule tags Protein binding/transferase
source organism Homo sapiens
molecule keywords Programmed cell death protein 10
total genus 29
structure length 67
sequence length 67
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2013-03-13
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.12.70 Mainly Alpha Orthogonal Bundle Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 3w8iB00
4GEHB 3RQFA 3L8JA 3L8IA 3W8HB 3AJMA 3W8IB 3RQGA 3RQEA
chains in the Genus database with same CATH superfamily
4U19A 1DCIA 2VX2A 3RQFA 3G64A 2HW5A 5KJPA 1MJ3A 3IRBA 3MYBA 3MOYA 3FDUA 4ELSA 3SWXA 4K3WA 4I42A 2EJ5A 4WCZA 3RSIA 2GTRA 1EY3A 4ELWA 3SLLA 4KNPA 3AM1A 4GEHB 3QK8A 3R9SA 1HZDA 4IZCA 1UIYA 3P5MA 3A4LA 2FBMA 3Q1TA 4MI2A 4QIIA 3T89A 3QXIA 3A4MA 1EF8A 3H81A 4I52A 3QXZA 4ELXA 4QIJA 4K2NA 4FZWA 3HINA 4FJWD 2QQ3A 2ZQQA 4IZDA 1EF9A 3PZKA 5JBXA 4JFCA 4JYLA 4U1AA 4NNQA 2FW2A 3RQEA 3OC7A 5JBWA 1UX5A 3ADBA 4JOTA 4JCSA 1Q52A 3Q0JA 3A4NA 4EMLA 3HRXA 4OLQA 3O4XE 3T8AA 3Q0GA 4FZWC 1Q51A 4MOUA 3TRRA 2UZFA 3R0OA 3W8IB 2VREA 1RJMA 2PBPA 4ZU2A 5C9GA 3ADDA 2DUBA 3TLFA 1JXZA 4JWVA 3RQGA 3L8IA 3AJMA 2ZQRA 3R9TA 4I4ZA 4OG1A 4U18A 2F6QA 3I47A 1NZYB 3L8JA 1NZYA 1RJNA 3ADCA 3H02A 1UX4A 4IZBA 3T88A 4NEKA 2PPYA 2IEXA 1WZ8A 3W8HB 4F47A 1DUBA 1Y64B 2P63A 3KQFA
chains in the Genus database with same CATH topology
3L8IA 3RQFA 3A4MA 3AJMA 1UX5A 3ADBA 3IRBA 3A4NA 3L8JA 3O4XE 3ADCA 1UX4A 3W8IB 1RJMA 3AM1A 4GEHB 3W8HB 3ADDA 1Y64B 2P63A 4NNQA 3A4LA 3RQGA 3RQEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GEH B;  3RQF A;  3L8J A;  3L8I A;  3W8H B;  3AJM A;  3W8I B;  3RQG A;  3RQE A; 
#chains in the Genus database with same CATH topology
 4U19 A;  1DCI A;  2VX2 A;  3RQF A;  3G64 A;  2HW5 A;  5KJP A;  1MJ3 A;  3IRB A;  3MYB A;  3MOY A;  3FDU A;  4ELS A;  3SWX A;  4K3W A;  4I42 A;  2EJ5 A;  4WCZ A;  3RSI A;  2GTR A;  1EY3 A;  4ELW A;  3SLL A;  4KNP A;  3AM1 A;  4GEH B;  3QK8 A;  3R9S A;  1HZD A;  4IZC A;  1UIY A;  3P5M A;  3A4L A;  2FBM A;  3Q1T A;  4MI2 A;  4QII A;  3T89 A;  3QXI A;  3A4M A;  1EF8 A;  3H81 A;  4I52 A;  3QXZ A;  4ELX A;  4QIJ A;  4K2N A;  4FZW A;  3HIN A;  4FJW D;  2QQ3 A;  2ZQQ A;  4IZD A;  1EF9 A;  3PZK A;  5JBX A;  4JFC A;  4JYL A;  4U1A A;  4NNQ A;  2FW2 A;  3RQE A;  3OC7 A;  5JBW A;  1UX5 A;  3ADB A;  4JOT A;  4JCS A;  1Q52 A;  3Q0J A;  3A4N A;  4EML A;  3HRX A;  4OLQ A;  3O4X E;  3T8A A;  3Q0G A;  4FZW C;  1Q51 A;  4MOU A;  3TRR A;  2UZF A;  3R0O A;  3W8I B;  2VRE A;  1RJM A;  2PBP A;  4ZU2 A;  5C9G A;  3ADD A;  2DUB A;  3TLF A;  1JXZ A;  4JWV A;  3RQG A;  3L8I A;  3AJM A;  2ZQR A;  3R9T A;  4I4Z A;  4OG1 A;  4U18 A;  2F6Q A;  3I47 A;  1NZY B;  3L8J A;  1NZY A;  1RJN A;  3ADC A;  3H02 A;  1UX4 A;  4IZB A;  3T88 A;  4NEK A;  2PPY A;  2IEX A;  1WZ8 A;  3W8H B;  4F47 A;  1DUB A;  1Y64 B;  2P63 A;  3KQF A; 
#chains in the Genus database with same CATH homology
 3L8I A;  3RQF A;  3A4M A;  3AJM A;  1UX5 A;  3ADB A;  3IRB A;  3A4N A;  3L8J A;  3O4X E;  3ADC A;  1UX4 A;  3W8I B;  1RJM A;  3AM1 A;  4GEH B;  3W8H B;  3ADD A;  1Y64 B;  2P63 A;  4NNQ A;  3A4L A;  3RQG A;  3RQE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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