3W8IB

Crystal structure of ccm3 in complex with the c-terminal regulatory domain of mst4
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
67
structure length
67
Chain Sequence
PGSMLVQTLSCLSMIITPAFAELKQQDENNASRNQAIEELEKSIAVAEAACPGITDKMVKKLIEKFQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis for the Unique Heterodimeric Assembly between Cerebral Cavernous Malformation 3 and Germinal Center Kinase III.
pubmed doi rcsb
molecule tags Protein binding/transferase
source organism Homo sapiens
molecule keywords Programmed cell death protein 10
total genus 29
structure length 67
sequence length 67
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2013-03-13
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.12.70 Mainly Alpha Orthogonal Bundle Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 3w8iB00
3RQFA 3L8JA 3RQEA 3W8HB 3RQGA 3AJMA 4GEHB 3W8IB 3L8IA
chains in the Genus database with same CATH superfamily
4IZBA 3MOYA 2GTRA 3Q0GA 2P63A 3HRXA 1DUBA 1NZYB 3R0OA 3SWXA 3Q1TA 4OLQA 2EJ5A 3QXIA 3MYBA 1UX4A 3A4NA 1HZDA 4I42A 4WCZA 3H81A 3ADDA 4ZU2A 5JBWA 1EY3A 4KNPA 3FDUA 3IRBA 3RQFA 4QIIA 3R9TA 1WZ8A 4U1AA 3RQGA 1EF8A 3QXZA 2QQ3A 2VREA 2F6QA 4U19A 4EMLA 2HW5A 3RSIA 2IEXA 3G64A 3KQFA 1MJ3A 3RQEA 2ZQRA 3Q0JA 3T8AA 3TLFA 4IZDA 1UIYA 1NZYA 3QK8A 3SLLA 1JXZA 4JWVA 4MOUA 4FZWC 1Q51A 4JCSA 4NNQA 4K2NA 3W8IB 3H02A 4FJWD 1RJNA 3A4LA 3HINA 3A4MA 3L8JA 4JYLA 2VX2A 3W8HB 4ELWA 3P5MA 3L8IA 4K3WA 4U18A 5KJPA 1Q52A 3T89A 1UX5A 3AM1A 4ELSA 2PPYA 1EF9A 2FBMA 3T88A 4I4ZA 5JBXA 4QIJA 3AJMA 4GEHB 5C9GA 3O4XE 3ADBA 4IZCA 4F47A 2FW2A 4OG1A 3PZKA 2PBPA 1RJMA 1Y64B 4I52A 4JFCA 3R9SA 2DUBA 3TRRA 3ADCA 4FZWA 3I47A 4ELXA 4JOTA 2ZQQA 1DCIA 3OC7A 4MI2A 2UZFA 4NEKA
chains in the Genus database with same CATH topology
3IRBA 3RQFA 3A4LA 3RQGA 2P63A 3A4MA 1RJMA 3L8JA 3RQEA 1Y64B 3W8HB 3L8IA 1UX5A 3AM1A 3ADCA 1UX4A 3A4NA 3ADDA 4NNQA 3AJMA 4GEHB 3W8IB 3O4XE 3ADBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3RQF A;  3L8J A;  3RQE A;  3W8H B;  3RQG A;  3AJM A;  4GEH B;  3W8I B;  3L8I A; 
#chains in the Genus database with same CATH topology
 4IZB A;  3MOY A;  2GTR A;  3Q0G A;  2P63 A;  3HRX A;  1DUB A;  1NZY B;  3R0O A;  3SWX A;  3Q1T A;  4OLQ A;  2EJ5 A;  3QXI A;  3MYB A;  1UX4 A;  3A4N A;  1HZD A;  4I42 A;  4WCZ A;  3H81 A;  3ADD A;  4ZU2 A;  5JBW A;  1EY3 A;  4KNP A;  3FDU A;  3IRB A;  3RQF A;  4QII A;  3R9T A;  1WZ8 A;  4U1A A;  3RQG A;  1EF8 A;  3QXZ A;  2QQ3 A;  2VRE A;  2F6Q A;  4U19 A;  4EML A;  2HW5 A;  3RSI A;  2IEX A;  3G64 A;  3KQF A;  1MJ3 A;  3RQE A;  2ZQR A;  3Q0J A;  3T8A A;  3TLF A;  4IZD A;  1UIY A;  1NZY A;  3QK8 A;  3SLL A;  1JXZ A;  4JWV A;  4MOU A;  4FZW C;  1Q51 A;  4JCS A;  4NNQ A;  4K2N A;  3W8I B;  3H02 A;  4FJW D;  1RJN A;  3A4L A;  3HIN A;  3A4M A;  3L8J A;  4JYL A;  2VX2 A;  3W8H B;  4ELW A;  3P5M A;  3L8I A;  4K3W A;  4U18 A;  5KJP A;  1Q52 A;  3T89 A;  1UX5 A;  3AM1 A;  4ELS A;  2PPY A;  1EF9 A;  2FBM A;  3T88 A;  4I4Z A;  5JBX A;  4QIJ A;  3AJM A;  4GEH B;  5C9G A;  3O4X E;  3ADB A;  4IZC A;  4F47 A;  2FW2 A;  4OG1 A;  3PZK A;  2PBP A;  1RJM A;  1Y64 B;  4I52 A;  4JFC A;  3R9S A;  2DUB A;  3TRR A;  3ADC A;  4FZW A;  3I47 A;  4ELX A;  4JOT A;  2ZQQ A;  1DCI A;  3OC7 A;  4MI2 A;  2UZF A;  4NEK A; 
#chains in the Genus database with same CATH homology
 3IRB A;  3RQF A;  3A4L A;  3RQG A;  2P63 A;  3A4M A;  1RJM A;  3L8J A;  3RQE A;  1Y64 B;  3W8H B;  3L8I A;  1UX5 A;  3AM1 A;  3ADC A;  1UX4 A;  3A4N A;  3ADD A;  4NNQ A;  3AJM A;  4GEH B;  3W8I B;  3O4X E;  3ADB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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