3UZAA

Thermostabilised adenosine a2a receptor in complex with 6-(2,6-dimethylpyridin-4-yl)-5-phenyl-1,2,4-triazin-3-amine
Total Genus 109
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
109
sequence length
299
structure length
291
Chain Sequence
SVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADILVGVLAIPFAITISTGFCAACHGCLFIACFVLVLAQSSIFSLLAIAIDRYIAIAIPLRYNGLVTGTRAAGIIAICWVLSFAIGLTPMLGWNNCGQPGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFAAARRQLKQMESQPLPGERARSTLQKEVHAAKSAAIIAGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLAHTNSVVNPFIYAYRIREFRQTFRKIIRS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of 1,2,4-Triazine Derivatives as Adenosine A(2A) Antagonists using Structure Based Drug Design
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Adenosine receptor A2a
total genus 109
structure length 291
sequence length 299
ec nomenclature
pdb deposition date 2011-12-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00001 7tm_1 7 transmembrane receptor (rhodopsin family)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1070.10 Mainly Alpha Up-down Bundle Rhopdopsin 7-helix transmembrane proteins Rhopdopsin 7-helix transmembrane proteins 3uzaA00
4IB4A 4IARA 2F93A 5AZDA 5AWZA 3PBLA 4LDEA 2WJKA 5H2IA 1QKPA 1C8SA 2HPYA 3NSBA 3QAPA 5JJEA 5LWEA 2YCYA 4HYXA 3EH4B 5H2OA 1KG8A 3PXOA 4OV0A 3PDSA 4HYJA 1S53A 4XTLA 3QJSB 2I21A 1TN5A 3HASA 3HAOA 1FBKA 3OAXA 3S3CB 2QPEB 3NS0A 3ZPQA 5J7AA 2X72A 2R4RA 3S8FB 1HZXA 5A45A 5BR2A 1JFPA 4G70B 4GP8B 3WQJA 4N4YB 1BRXA 4BUOA 5B2NA 2I20A 1KMEA 3VI0A 3QJUB 3QJRB 1CWQA 1C8RA 4AMJA 2ZFEA 1P8UA 3V2YA 1Q5IA 3S3BB 5F8UA 2Y02A 5B6XA 5ITCA 4FA7B 1GZMA 5AX1A 3EMLA 5JJJA 3P0GA 4BWBA 3UTXA 5FJGA 1S51A 5H2KA 3UONA 2KSBA 1QHJA 3PWHA 4G7SB 4A4MA 1L9HA 1X0I1 1JGJA 3OE6A 2ZIYA 4EIYA 4EJ4A 5JJNA 4WW3A 3V2WA 1GUEA 4BEYA 2KSAA 3QBGA 1BRDA 4XT1A 4IAQA 1PXSA 3NY8A 2YDVA 5ETZA 1AT9A 1KG9A 4X31A 5TGZA 1M0LA 1AP9A 2NTUA 5B6WA 5G2CA 4X1HA 1VGOA 3UTYA 1L0MA 1FBBA 1IW6A 5A8EA 3UTVA 1X0SA 4QI1A 3VG9A 4PXFA 4GBRA 2PEDA 4XXJA 3ABWA 2M3GA 2L6XA 4FPDA 5G2DA 4JQ6A 5DHHA 1MGYA 3HANA 3AYMA 5AHZA 3A7KA 1XMEB 2BRDA 1F88A 2NTWA 3OE8A 3NY9A 3DDLA 4KNFA 2EI4A 3ODUA 4BEZA 4GP5B 1C3WA 4HWLA 3RZEA 1XJIA 3UZCA 1IXFA 2VT4A 3D4SA 4GPOA 3NYAA 4UG2A 5H2MA 3PQRA 4Y9HA 2LNLA 2AT9A 1S8JA 3REYA 3QBIA 3X3CA 3AM6A 5H2JA 3EH3B 1LN6A 3ZPRA 5AX0A 3QAKA 1S54A 4L35A 1E12A 2R4SA 4MQSA 5B35A 4N6HA 3C9LA 1TN0A 3QBLA 4LDLA 1S52A 4QIDA 5EN0A 5ITEA 1R84A 4DKLA 4GP4B 1UCQA 1O0AA 2JAGA 4GRVA 2KS9A 2F95A 1UAZA 1BM1A 1PY6A 3RFMA 2Y01A 5H2PA 1X0K1 3OE0A 3OE9A 5BR5A 1F50A 1P8IA 4MQTA 4LDOA 4DAJA 3X3BA 1H68A 1PXRA 1BRRA 2QPDB 1P8HA 3C9MA 3BVDB 5G53A 4NC3A 4QRYA 1U19A 4FBZA 4BV0A 1GU8A 2Y03A 4XT3A 5C1MA 5H2HA 4DJHA 3QJQB 4MD2A 4G7RB 4GYCA 2YCXA 3UG9A 1QM8A 1Q5JA 3KJ6A 3ZEVA 5G2AA 2WJLA 3QBKA 4J4QA 4PXKA 2Z55A 2JAFA 3QDCA 5A44A 1R2NA 4AMIA 5B0WA 4K5YA 2I1XA 4EA3A 4TL3A 4G72B 5H2NA 1M0KA 3HARA 4WAVA 5AHYA 4N4WA 3COCA 3EH5B 3S3DB 4KLYA 5B34A 1JV7A 3HAPA 2YCWA 1H2SA 2Z73A 1XIOA 4XTNA 3VW7A 2G87A 4BVNA 2RH1A 2YDOA 4JR8A 1E0PA 4MBSA 4XTOA 1KGBA 3UTWA 3T45A 3SN6R 1JV6A 1IW9A 2YCZA 3DQBA 2KSYA 3S8GB 5B6VA 4UHRA 1M0MA 4G7QB 2ZZLA 3MBVA 5G54A 5B6ZA 2I35A 2J4YA 3AYNA 1VJMA 4FAAB 3VHZA 3VGAA 4JKVA 4X32A 3CAPA 5H2LA 1F4ZA 5G36A 1EHKB 5G28A 1QKOA 3QJVB 3HAQA 2Y04A 5DYSA 5DHGA 4MD1A 3CODA 2Y00A 4L6RA 3UZAA 5B6YA 1DZEA 3QJTB 5KKHA 1S8LA 4G71B 3VVKA
chains in the Genus database with same CATH superfamily
4IB4A 4IARA 2F93A 5AZDA 5AWZA 3PBLA 4LDEA 2WJKA 5H2IA 1QKPA 1C8SA 2HPYA 3NSBA 3QAPA 5JJEA 5LWEA 2YCYA 4HYXA 3EH4B 5H2OA 1KG8A 3PXOA 4OV0A 3PDSA 4HYJA 1S53A 4XTLA 3QJSB 2I21A 1TN5A 3HASA 3HAOA 1FBKA 3OAXA 3S3CB 2QPEB 3NS0A 3ZPQA 5J7AA 2X72A 2R4RA 3S8FB 1HZXA 5A45A 5BR2A 1JFPA 4G70B 4GP8B 3WQJA 4N4YB 1BRXA 4BUOA 5B2NA 2I20A 1KMEA 3VI0A 3QJUB 3QJRB 1CWQA 1C8RA 4AMJA 2ZFEA 1P8UA 3V2YA 1Q5IA 3S3BB 5F8UA 2Y02A 5B6XA 5ITCA 4FA7B 1GZMA 5AX1A 3EMLA 5JJJA 3P0GA 4BWBA 3UTXA 5FJGA 1S51A 5H2KA 3UONA 2KSBA 1QHJA 3PWHA 4G7SB 4A4MA 1L9HA 1X0I1 1JGJA 3OE6A 2ZIYA 4EIYA 4EJ4A 5JJNA 4WW3A 3V2WA 1GUEA 4BEYA 2KSAA 3QBGA 1BRDA 4XT1A 4IAQA 1PXSA 3NY8A 2YDVA 5ETZA 1AT9A 1KG9A 4X31A 5TGZA 1M0LA 1AP9A 2NTUA 5B6WA 5G2CA 4X1HA 1VGOA 3UTYA 1L0MA 1FBBA 1IW6A 5A8EA 3UTVA 1X0SA 4QI1A 3VG9A 4PXFA 4GBRA 2PEDA 4XXJA 3ABWA 2M3GA 2L6XA 4FPDA 5G2DA 4JQ6A 5DHHA 1MGYA 4DS7E 3HANA 3AYMA 5AHZA 3A7KA 1XMEB 2BRDA 1F88A 2NTWA 3OE8A 3NY9A 3DDLA 4KNFA 2EI4A 3ODUA 4BEZA 4GP5B 1C3WA 4HWLA 3RZEA 1XJIA 3UZCA 1IXFA 2VT4A 3D4SA 4GPOA 3NYAA 4UG2A 5H2MA 3PQRA 4Y9HA 2LNLA 2AT9A 1S8JA 3REYA 3QBIA 3X3CA 3AM6A 5H2JA 3EH3B 1LN6A 3ZPRA 5AX0A 3QAKA 1S54A 4L35A 1E12A 2R4SA 4MQSA 5B35A 4N6HA 3C9LA 1TN0A 3QBLA 4LDLA 1S52A 4QIDA 5EN0A 5ITEA 1R84A 4DKLA 4GP4B 1UCQA 1O0AA 2JAGA 4GRVA 2KS9A 2F95A 1UAZA 1BM1A 1PY6A 3RFMA 2Y01A 5H2PA 1X0K1 3OE0A 3OE9A 5BR5A 1F50A 1P8IA 4MQTA 4LDOA 4DAJA 3X3BA 1H68A 1PXRA 1BRRA 2QPDB 1P8HA 3C9MA 3BVDB 5G53A 4NC3A 4QRYA 1U19A 4FBZA 4BV0A 1GU8A 2Y03A 4XT3A 5C1MA 5H2HA 4DJHA 3QJQB 4MD2A 4G7RB 4GYCA 2YCXA 3UG9A 1QM8A 1Q5JA 3KJ6A 3ZEVA 5G2AA 2WJLA 3QBKA 4J4QA 4PXKA 2Z55A 2JAFA 3QDCA 5A44A 1R2NA 4AMIA 5B0WA 4K5YA 2I1XA 4EA3A 4TL3A 4G72B 5H2NA 1M0KA 3HARA 4WAVA 5AHYA 4N4WA 3COCA 3EH5B 3S3DB 4KLYA 5B34A 1JV7A 3HAPA 2YCWA 1H2SA 2Z73A 1XIOA 4XTNA 3VW7A 2G87A 4BVNA 2RH1A 2YDOA 4JR8A 1E0PA 4MBSA 4XTOA 1KGBA 3UTWA 3T45A 3SN6R 1JV6A 1IW9A 2YCZA 3DQBA 2KSYA 3S8GB 5B6VA 4UHRA 1M0MA 4G7QB 2ZZLA 3MBVA 5G54A 5B6ZA 2I35A 2J4YA 3AYNA 1VJMA 4FAAB 3VHZA 3VGAA 4JKVA 4X32A 3CAPA 5H2LA 1F4ZA 5G36A 1EHKB 5G28A 1QKOA 3QJVB 3HAQA 2Y04A 5DYSA 5DHGA 4MD1A 3CODA 2Y00A 4L6RA 3UZAA 5B6YA 1DZEA 3QJTB 5KKHA 1S8LA 4G71B 3VVKA
chains in the Genus database with same CATH topology
4IB4A 4IARA 2F93A 5AZDA 5AWZA 3PBLA 4LDEA 2WJKA 5H2IA 1QKPA 1C8SA 2HPYA 3NSBA 3QAPA 5JJEA 5LWEA 2YCYA 4HYXA 3EH4B 5H2OA 1KG8A 3PXOA 4OV0A 3PDSA 4HYJA 1S53A 4XTLA 3QJSB 2I21A 1TN5A 3HASA 3HAOA 1FBKA 3OAXA 3S3CB 2QPEB 3NS0A 3ZPQA 5J7AA 2X72A 2R4RA 3S8FB 1HZXA 5A45A 5BR2A 1JFPA 4G70B 4GP8B 3WQJA 4N4YB 1BRXA 4BUOA 5B2NA 2I20A 1KMEA 3VI0A 3QJUB 3QJRB 1CWQA 1C8RA 4AMJA 2ZFEA 1P8UA 3V2YA 1Q5IA 3S3BB 5F8UA 2Y02A 5B6XA 5ITCA 4FA7B 1GZMA 5AX1A 3EMLA 5JJJA 3P0GA 4BWBA 3UTXA 5FJGA 1S51A 5H2KA 3UONA 2KSBA 1QHJA 3PWHA 4G7SB 4A4MA 1L9HA 1X0I1 1JGJA 3OE6A 2ZIYA 4EIYA 4EJ4A 5JJNA 4WW3A 3V2WA 1GUEA 4BEYA 2KSAA 3QBGA 1BRDA 4XT1A 4IAQA 1PXSA 3NY8A 2YDVA 5ETZA 1AT9A 1KG9A 4X31A 5TGZA 1M0LA 1AP9A 2NTUA 5B6WA 5G2CA 4X1HA 1VGOA 3UTYA 1L0MA 1FBBA 1IW6A 5A8EA 3UTVA 1X0SA 4QI1A 3VG9A 4PXFA 4GBRA 2PEDA 4XXJA 3ABWA 2M3GA 2L6XA 4FPDA 5G2DA 4JQ6A 5DHHA 1MGYA 4DS7E 3HANA 3AYMA 5AHZA 3A7KA 1XMEB 2BRDA 1F88A 2NTWA 3OE8A 3NY9A 3DDLA 4KNFA 2EI4A 3ODUA 4BEZA 4GP5B 1C3WA 4HWLA 3RZEA 1XJIA 3UZCA 1IXFA 2VT4A 3D4SA 4GPOA 3NYAA 4UG2A 5H2MA 3PQRA 4Y9HA 2LNLA 2AT9A 1S8JA 3REYA 3QBIA 3X3CA 3AM6A 5H2JA 3EH3B 1LN6A 3ZPRA 5AX0A 3QAKA 1S54A 4L35A 1E12A 2R4SA 4MQSA 5B35A 4N6HA 3C9LA 1TN0A 3QBLA 4LDLA 1S52A 4QIDA 5EN0A 5ITEA 1R84A 4DKLA 4GP4B 1UCQA 1O0AA 2JAGA 4GRVA 2KS9A 2F95A 1UAZA 1BM1A 1PY6A 3RFMA 2Y01A 5H2PA 1X0K1 3OE0A 3OE9A 5BR5A 1F50A 1P8IA 4MQTA 4LDOA 4DAJA 3X3BA 1H68A 1PXRA 1BRRA 2QPDB 1P8HA 3C9MA 3BVDB 5G53A 4NC3A 4QRYA 1U19A 4FBZA 4BV0A 1GU8A 2Y03A 4XT3A 5C1MA 5H2HA 4DJHA 3QJQB 4MD2A 4G7RB 4GYCA 2YCXA 3UG9A 1QM8A 1Q5JA 3KJ6A 3ZEVA 5G2AA 2WJLA 3QBKA 4J4QA 4PXKA 2Z55A 2JAFA 3QDCA 5A44A 1R2NA 4AMIA 5B0WA 4K5YA 2I1XA 4EA3A 4TL3A 4G72B 5H2NA 1M0KA 3HARA 4WAVA 5AHYA 4N4WA 3COCA 3EH5B 3S3DB 4KLYA 5B34A 1JV7A 3HAPA 2YCWA 1H2SA 2Z73A 1XIOA 4XTNA 3VW7A 2G87A 4BVNA 2RH1A 2YDOA 4JR8A 1E0PA 4MBSA 4XTOA 1KGBA 3UTWA 3T45A 3SN6R 1JV6A 1IW9A 2YCZA 3DQBA 2KSYA 3S8GB 5B6VA 4UHRA 1M0MA 4G7QB 2ZZLA 3MBVA 5G54A 5B6ZA 2I35A 2J4YA 3AYNA 1VJMA 4FAAB 3VHZA 3VGAA 4JKVA 4X32A 3CAPA 5H2LA 1F4ZA 5G36A 1EHKB 5G28A 1QKOA 3QJVB 3HAQA 2Y04A 5DYSA 5DHGA 4MD1A 3CODA 2Y00A 4L6RA 3UZAA 5B6YA 1DZEA 3QJTB 5KKHA 1S8LA 4G71B 3VVKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IB4 A;  4IAR A;  2F93 A;  5AZD A;  5AWZ A;  3PBL A;  4LDE A;  2WJK A;  5H2I A;  1QKP A;  1C8S A;  2HPY A;  3NSB A;  3QAP A;  5JJE A;  5LWE A;  2YCY A;  4HYX A;  3EH4 B;  5H2O A;  1KG8 A;  3PXO A;  4OV0 A;  3PDS A;  4HYJ A;  1S53 A;  4XTL A;  3QJS B;  2I21 A;  1TN5 A;  3HAS A;  3HAO A;  1FBK A;  3OAX A;  3S3C B;  2QPE B;  3NS0 A;  3ZPQ A;  5J7A A;  2X72 A;  2R4R A;  3S8F B;  1HZX A;  5A45 A;  5BR2 A;  1JFP A;  4G70 B;  4GP8 B;  3WQJ A;  4N4Y B;  1BRX A;  4BUO A;  5B2N A;  2I20 A;  1KME A;  3VI0 A;  3QJU B;  3QJR B;  1CWQ A;  1C8R A;  4AMJ A;  2ZFE A;  1P8U A;  3V2Y A;  1Q5I A;  3S3B B;  5F8U A;  2Y02 A;  5B6X A;  5ITC A;  4FA7 B;  1GZM A;  5AX1 A;  3EML A;  5JJJ A;  3P0G A;  4BWB A;  3UTX A;  5FJG A;  1S51 A;  5H2K A;  3UON A;  2KSB A;  1QHJ A;  3PWH A;  4G7S B;  4A4M A;  1L9H A;  1X0I 1;  1JGJ A;  3OE6 A;  2ZIY A;  4EIY A;  4EJ4 A;  5JJN A;  4WW3 A;  3V2W A;  1GUE A;  4BEY A;  2KSA A;  3QBG A;  1BRD A;  4XT1 A;  4IAQ A;  1PXS A;  3NY8 A;  2YDV A;  5ETZ A;  1AT9 A;  1KG9 A;  4X31 A;  5TGZ A;  1M0L A;  1AP9 A;  2NTU A;  5B6W A;  5G2C A;  4X1H A;  1VGO A;  3UTY A;  1L0M A;  1FBB A;  1IW6 A;  5A8E A;  3UTV A;  1X0S A;  4QI1 A;  3VG9 A;  4PXF A;  4GBR A;  2PED A;  4XXJ A;  3ABW A;  2M3G A;  2L6X A;  4FPD A;  5G2D A;  4JQ6 A;  5DHH A;  1MGY A;  3HAN A;  3AYM A;  5AHZ A;  3A7K A;  1XME B;  2BRD A;  1F88 A;  2NTW A;  3OE8 A;  3NY9 A;  3DDL A;  4KNF A;  2EI4 A;  3ODU A;  4BEZ A;  4GP5 B;  1C3W A;  4HWL A;  3RZE A;  1XJI A;  3UZC A;  1IXF A;  2VT4 A;  3D4S A;  4GPO A;  3NYA A;  4UG2 A;  5H2M A;  3PQR A;  4Y9H A;  2LNL A;  2AT9 A;  1S8J A;  3REY A;  3QBI A;  3X3C A;  3AM6 A;  5H2J A;  3EH3 B;  1LN6 A;  3ZPR A;  5AX0 A;  3QAK A;  1S54 A;  4L35 A;  1E12 A;  2R4S A;  4MQS A;  5B35 A;  4N6H A;  3C9L A;  1TN0 A;  3QBL A;  4LDL A;  1S52 A;  4QID A;  5EN0 A;  5ITE A;  1R84 A;  4DKL A;  4GP4 B;  1UCQ A;  1O0A A;  2JAG A;  4GRV A;  2KS9 A;  2F95 A;  1UAZ A;  1BM1 A;  1PY6 A;  3RFM A;  2Y01 A;  5H2P A;  1X0K 1;  3OE0 A;  3OE9 A;  5BR5 A;  1F50 A;  1P8I A;  4MQT A;  4LDO A;  4DAJ A;  3X3B A;  1H68 A;  1PXR A;  1BRR A;  2QPD B;  1P8H A;  3C9M A;  3BVD B;  5G53 A;  4NC3 A;  4QRY A;  1U19 A;  4FBZ A;  4BV0 A;  1GU8 A;  2Y03 A;  4XT3 A;  5C1M A;  5H2H A;  4DJH A;  3QJQ B;  4MD2 A;  4G7R B;  4GYC A;  2YCX A;  3UG9 A;  1QM8 A;  1Q5J A;  3KJ6 A;  3ZEV A;  5G2A A;  2WJL A;  3QBK A;  4J4Q A;  4PXK A;  2Z55 A;  2JAF A;  3QDC A;  5A44 A;  1R2N A;  4AMI A;  5B0W A;  4K5Y A;  2I1X A;  4EA3 A;  4TL3 A;  4G72 B;  5H2N A;  1M0K A;  3HAR A;  4WAV A;  5AHY A;  4N4W A;  3COC A;  3EH5 B;  3S3D B;  4KLY A;  5B34 A;  1JV7 A;  3HAP A;  2YCW A;  1H2S A;  2Z73 A;  1XIO A;  4XTN A;  3VW7 A;  2G87 A;  4BVN A;  2RH1 A;  2YDO A;  4JR8 A;  1E0P A;  4MBS A;  4XTO A;  1KGB A;  3UTW A;  3T45 A;  3SN6 R;  1JV6 A;  1IW9 A;  2YCZ A;  3DQB A;  2KSY A;  3S8G B;  5B6V A;  4UHR A;  1M0M A;  4G7Q B;  2ZZL A;  3MBV A;  5G54 A;  5B6Z A;  2I35 A;  2J4Y A;  3AYN A;  1VJM A;  4FAA B;  3VHZ A;  3VGA A;  4JKV A;  4X32 A;  3CAP A;  5H2L A;  1F4Z A;  5G36 A;  1EHK B;  5G28 A;  1QKO A;  3QJV B;  3HAQ A;  2Y04 A;  5DYS A;  5DHG A;  4MD1 A;  3COD A;  2Y00 A;  4L6R A;  3UZA A;  5B6Y A;  1DZE A;  3QJT B;  5KKH A;  1S8L A;  4G71 B;  3VVK A; 
#chains in the Genus database with same CATH topology
 4IB4 A;  4IAR A;  2F93 A;  5AZD A;  5AWZ A;  3PBL A;  4LDE A;  2WJK A;  5H2I A;  1QKP A;  1C8S A;  2HPY A;  3NSB A;  3QAP A;  5JJE A;  5LWE A;  2YCY A;  4HYX A;  3EH4 B;  5H2O A;  1KG8 A;  3PXO A;  4OV0 A;  3PDS A;  4HYJ A;  1S53 A;  4XTL A;  3QJS B;  2I21 A;  1TN5 A;  3HAS A;  3HAO A;  1FBK A;  3OAX A;  3S3C B;  2QPE B;  3NS0 A;  3ZPQ A;  5J7A A;  2X72 A;  2R4R A;  3S8F B;  1HZX A;  5A45 A;  5BR2 A;  1JFP A;  4G70 B;  4GP8 B;  3WQJ A;  4N4Y B;  1BRX A;  4BUO A;  5B2N A;  2I20 A;  1KME A;  3VI0 A;  3QJU B;  3QJR B;  1CWQ A;  1C8R A;  4AMJ A;  2ZFE A;  1P8U A;  3V2Y A;  1Q5I A;  3S3B B;  5F8U A;  2Y02 A;  5B6X A;  5ITC A;  4FA7 B;  1GZM A;  5AX1 A;  3EML A;  5JJJ A;  3P0G A;  4BWB A;  3UTX A;  5FJG A;  1S51 A;  5H2K A;  3UON A;  2KSB A;  1QHJ A;  3PWH A;  4G7S B;  4A4M A;  1L9H A;  1X0I 1;  1JGJ A;  3OE6 A;  2ZIY A;  4EIY A;  4EJ4 A;  5JJN A;  4WW3 A;  3V2W A;  1GUE A;  4BEY A;  2KSA A;  3QBG A;  1BRD A;  4XT1 A;  4IAQ A;  1PXS A;  3NY8 A;  2YDV A;  5ETZ A;  1AT9 A;  1KG9 A;  4X31 A;  5TGZ A;  1M0L A;  1AP9 A;  2NTU A;  5B6W A;  5G2C A;  4X1H A;  1VGO A;  3UTY A;  1L0M A;  1FBB A;  1IW6 A;  5A8E A;  3UTV A;  1X0S A;  4QI1 A;  3VG9 A;  4PXF A;  4GBR A;  2PED A;  4XXJ A;  3ABW A;  2M3G A;  2L6X A;  4FPD A;  5G2D A;  4JQ6 A;  5DHH A;  1MGY A;  4DS7 E;  3HAN A;  3AYM A;  5AHZ A;  3A7K A;  1XME B;  2BRD A;  1F88 A;  2NTW A;  3OE8 A;  3NY9 A;  3DDL A;  4KNF A;  2EI4 A;  3ODU A;  4BEZ A;  4GP5 B;  1C3W A;  4HWL A;  3RZE A;  1XJI A;  3UZC A;  1IXF A;  2VT4 A;  3D4S A;  4GPO A;  3NYA A;  4UG2 A;  5H2M A;  3PQR A;  4Y9H A;  2LNL A;  2AT9 A;  1S8J A;  3REY A;  3QBI A;  3X3C A;  3AM6 A;  5H2J A;  3EH3 B;  1LN6 A;  3ZPR A;  5AX0 A;  3QAK A;  1S54 A;  4L35 A;  1E12 A;  2R4S A;  4MQS A;  5B35 A;  4N6H A;  3C9L A;  1TN0 A;  3QBL A;  4LDL A;  1S52 A;  4QID A;  5EN0 A;  5ITE A;  1R84 A;  4DKL A;  4GP4 B;  1UCQ A;  1O0A A;  2JAG A;  4GRV A;  2KS9 A;  2F95 A;  1UAZ A;  1BM1 A;  1PY6 A;  3RFM A;  2Y01 A;  5H2P A;  1X0K 1;  3OE0 A;  3OE9 A;  5BR5 A;  1F50 A;  1P8I A;  4MQT A;  4LDO A;  4DAJ A;  3X3B A;  1H68 A;  1PXR A;  1BRR A;  2QPD B;  1P8H A;  3C9M A;  3BVD B;  5G53 A;  4NC3 A;  4QRY A;  1U19 A;  4FBZ A;  4BV0 A;  1GU8 A;  2Y03 A;  4XT3 A;  5C1M A;  5H2H A;  4DJH A;  3QJQ B;  4MD2 A;  4G7R B;  4GYC A;  2YCX A;  3UG9 A;  1QM8 A;  1Q5J A;  3KJ6 A;  3ZEV A;  5G2A A;  2WJL A;  3QBK A;  4J4Q A;  4PXK A;  2Z55 A;  2JAF A;  3QDC A;  5A44 A;  1R2N A;  4AMI A;  5B0W A;  4K5Y A;  2I1X A;  4EA3 A;  4TL3 A;  4G72 B;  5H2N A;  1M0K A;  3HAR A;  4WAV A;  5AHY A;  4N4W A;  3COC A;  3EH5 B;  3S3D B;  4KLY A;  5B34 A;  1JV7 A;  3HAP A;  2YCW A;  1H2S A;  2Z73 A;  1XIO A;  4XTN A;  3VW7 A;  2G87 A;  4BVN A;  2RH1 A;  2YDO A;  4JR8 A;  1E0P A;  4MBS A;  4XTO A;  1KGB A;  3UTW A;  3T45 A;  3SN6 R;  1JV6 A;  1IW9 A;  2YCZ A;  3DQB A;  2KSY A;  3S8G B;  5B6V A;  4UHR A;  1M0M A;  4G7Q B;  2ZZL A;  3MBV A;  5G54 A;  5B6Z A;  2I35 A;  2J4Y A;  3AYN A;  1VJM A;  4FAA B;  3VHZ A;  3VGA A;  4JKV A;  4X32 A;  3CAP A;  5H2L A;  1F4Z A;  5G36 A;  1EHK B;  5G28 A;  1QKO A;  3QJV B;  3HAQ A;  2Y04 A;  5DYS A;  5DHG A;  4MD1 A;  3COD A;  2Y00 A;  4L6R A;  3UZA A;  5B6Y A;  1DZE A;  3QJT B;  5KKH A;  1S8L A;  4G71 B;  3VVK A; 
#chains in the Genus database with same CATH homology
 4IB4 A;  4IAR A;  2F93 A;  5AZD A;  5AWZ A;  3PBL A;  4LDE A;  2WJK A;  5H2I A;  1QKP A;  1C8S A;  2HPY A;  3NSB A;  3QAP A;  5JJE A;  5LWE A;  2YCY A;  4HYX A;  3EH4 B;  5H2O A;  1KG8 A;  3PXO A;  4OV0 A;  3PDS A;  4HYJ A;  1S53 A;  4XTL A;  3QJS B;  2I21 A;  1TN5 A;  3HAS A;  3HAO A;  1FBK A;  3OAX A;  3S3C B;  2QPE B;  3NS0 A;  3ZPQ A;  5J7A A;  2X72 A;  2R4R A;  3S8F B;  1HZX A;  5A45 A;  5BR2 A;  1JFP A;  4G70 B;  4GP8 B;  3WQJ A;  4N4Y B;  1BRX A;  4BUO A;  5B2N A;  2I20 A;  1KME A;  3VI0 A;  3QJU B;  3QJR B;  1CWQ A;  1C8R A;  4AMJ A;  2ZFE A;  1P8U A;  3V2Y A;  1Q5I A;  3S3B B;  5F8U A;  2Y02 A;  5B6X A;  5ITC A;  4FA7 B;  1GZM A;  5AX1 A;  3EML A;  5JJJ A;  3P0G A;  4BWB A;  3UTX A;  5FJG A;  1S51 A;  5H2K A;  3UON A;  2KSB A;  1QHJ A;  3PWH A;  4G7S B;  4A4M A;  1L9H A;  1X0I 1;  1JGJ A;  3OE6 A;  2ZIY A;  4EIY A;  4EJ4 A;  5JJN A;  4WW3 A;  3V2W A;  1GUE A;  4BEY A;  2KSA A;  3QBG A;  1BRD A;  4XT1 A;  4IAQ A;  1PXS A;  3NY8 A;  2YDV A;  5ETZ A;  1AT9 A;  1KG9 A;  4X31 A;  5TGZ A;  1M0L A;  1AP9 A;  2NTU A;  5B6W A;  5G2C A;  4X1H A;  1VGO A;  3UTY A;  1L0M A;  1FBB A;  1IW6 A;  5A8E A;  3UTV A;  1X0S A;  4QI1 A;  3VG9 A;  4PXF A;  4GBR A;  2PED A;  4XXJ A;  3ABW A;  2M3G A;  2L6X A;  4FPD A;  5G2D A;  4JQ6 A;  5DHH A;  1MGY A;  4DS7 E;  3HAN A;  3AYM A;  5AHZ A;  3A7K A;  1XME B;  2BRD A;  1F88 A;  2NTW A;  3OE8 A;  3NY9 A;  3DDL A;  4KNF A;  2EI4 A;  3ODU A;  4BEZ A;  4GP5 B;  1C3W A;  4HWL A;  3RZE A;  1XJI A;  3UZC A;  1IXF A;  2VT4 A;  3D4S A;  4GPO A;  3NYA A;  4UG2 A;  5H2M A;  3PQR A;  4Y9H A;  2LNL A;  2AT9 A;  1S8J A;  3REY A;  3QBI A;  3X3C A;  3AM6 A;  5H2J A;  3EH3 B;  1LN6 A;  3ZPR A;  5AX0 A;  3QAK A;  1S54 A;  4L35 A;  1E12 A;  2R4S A;  4MQS A;  5B35 A;  4N6H A;  3C9L A;  1TN0 A;  3QBL A;  4LDL A;  1S52 A;  4QID A;  5EN0 A;  5ITE A;  1R84 A;  4DKL A;  4GP4 B;  1UCQ A;  1O0A A;  2JAG A;  4GRV A;  2KS9 A;  2F95 A;  1UAZ A;  1BM1 A;  1PY6 A;  3RFM A;  2Y01 A;  5H2P A;  1X0K 1;  3OE0 A;  3OE9 A;  5BR5 A;  1F50 A;  1P8I A;  4MQT A;  4LDO A;  4DAJ A;  3X3B A;  1H68 A;  1PXR A;  1BRR A;  2QPD B;  1P8H A;  3C9M A;  3BVD B;  5G53 A;  4NC3 A;  4QRY A;  1U19 A;  4FBZ A;  4BV0 A;  1GU8 A;  2Y03 A;  4XT3 A;  5C1M A;  5H2H A;  4DJH A;  3QJQ B;  4MD2 A;  4G7R B;  4GYC A;  2YCX A;  3UG9 A;  1QM8 A;  1Q5J A;  3KJ6 A;  3ZEV A;  5G2A A;  2WJL A;  3QBK A;  4J4Q A;  4PXK A;  2Z55 A;  2JAF A;  3QDC A;  5A44 A;  1R2N A;  4AMI A;  5B0W A;  4K5Y A;  2I1X A;  4EA3 A;  4TL3 A;  4G72 B;  5H2N A;  1M0K A;  3HAR A;  4WAV A;  5AHY A;  4N4W A;  3COC A;  3EH5 B;  3S3D B;  4KLY A;  5B34 A;  1JV7 A;  3HAP A;  2YCW A;  1H2S A;  2Z73 A;  1XIO A;  4XTN A;  3VW7 A;  2G87 A;  4BVN A;  2RH1 A;  2YDO A;  4JR8 A;  1E0P A;  4MBS A;  4XTO A;  1KGB A;  3UTW A;  3T45 A;  3SN6 R;  1JV6 A;  1IW9 A;  2YCZ A;  3DQB A;  2KSY A;  3S8G B;  5B6V A;  4UHR A;  1M0M A;  4G7Q B;  2ZZL A;  3MBV A;  5G54 A;  5B6Z A;  2I35 A;  2J4Y A;  3AYN A;  1VJM A;  4FAA B;  3VHZ A;  3VGA A;  4JKV A;  4X32 A;  3CAP A;  5H2L A;  1F4Z A;  5G36 A;  1EHK B;  5G28 A;  1QKO A;  3QJV B;  3HAQ A;  2Y04 A;  5DYS A;  5DHG A;  4MD1 A;  3COD A;  2Y00 A;  4L6R A;  3UZA A;  5B6Y A;  1DZE A;  3QJT B;  5KKH A;  1S8L A;  4G71 B;  3VVK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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