4GEHB

Crystal structure of mst4 dimerization domain complex with pdcd10
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
66
structure length
65
Chain Sequence
DLVQTSCLSMIITPAFAELKQQDENNASRNQAIEELEKSIAVAEAACPGITDKMVKKLIEKFQKC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural mechanism of CCM3 heterodimerization with GCKIII kinases
pubmed doi rcsb
molecule tags Protein binding/transferase
source organism Homo sapiens
molecule keywords Programmed cell death protein 10
total genus 26
structure length 65
sequence length 66
chains with identical sequence D
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2012-08-02
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.12.70 Mainly Alpha Orthogonal Bundle Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 4gehB00
3RQGA 3W8HB 3RQFA 3L8IA 3RQEA 4GEHB 3AJMA 3L8JA 3W8IB
chains in the Genus database with same CATH superfamily
4JOTA 4JCSA 2QQ3A 3L8JA 2IEXA 3ADDA 4ELWA 1UX5A 3SLLA 2PBPA 4NEKA 2VREA 5JBXA 3ADBA 4NNQA 3G64A 3RQFA 1EF9A 3RSIA 1WZ8A 1EF8A 4FJWD 4JWVA 2GTRA 3MOYA 4K3WA 4WCZA 2FW2A 3Q0JA 4JYLA 4IZDA 3IRBA 4GEHB 4K2NA 1DCIA 1Y64B 3A4NA 3P5MA 4KNPA 4I42A 4IZBA 4FZWA 4IZCA 4U18A 3Q0GA 1RJNA 3MYBA 3O4XE 5JBWA 5C9GA 4I52A 4OG1A 1Q51A 2VX2A 3L8IA 3RQEA 1UX4A 3HINA 3HRXA 1NZYB 2ZQQA 3KQFA 3W8IB 1HZDA 3SWXA 2F6QA 3OC7A 2ZQRA 4QIIA 4U19A 4ELXA 4FZWC 3ADCA 2P63A 2HW5A 2FBMA 3W8HB 3QXZA 3T88A 3FDUA 4MI2A 3H81A 3QXIA 1NZYA 3R9TA 3T89A 4EMLA 3A4MA 3T8AA 3AJMA 4OLQA 3R0OA 1EY3A 2PPYA 3R9SA 1DUBA 3TRRA 3H02A 1UIYA 4JFCA 4ZU2A 3I47A 1JXZA 3TLFA 1MJ3A 3QK8A 3RQGA 4QIJA 4U1AA 2UZFA 1RJMA 2EJ5A 3A4LA 4I4ZA 5KJPA 1Q52A 4F47A 3AM1A 4MOUA 3Q1TA 2DUBA 3PZKA 4ELSA
chains in the Genus database with same CATH topology
3IRBA 3A4MA 4GEHB 3AJMA 3L8JA 3ADDA 1Y64B 3A4NA 3W8IB 1UX5A 3ADBA 3ADCA 2P63A 4NNQA 3RQGA 3W8HB 3RQFA 1RJMA 3O4XE 3A4LA 3L8IA 3RQEA 1UX4A 3AM1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3RQG A;  3W8H B;  3RQF A;  3L8I A;  3RQE A;  4GEH B;  3AJM A;  3L8J A;  3W8I B; 
#chains in the Genus database with same CATH topology
 4JOT A;  4JCS A;  2QQ3 A;  3L8J A;  2IEX A;  3ADD A;  4ELW A;  1UX5 A;  3SLL A;  2PBP A;  4NEK A;  2VRE A;  5JBX A;  3ADB A;  4NNQ A;  3G64 A;  3RQF A;  1EF9 A;  3RSI A;  1WZ8 A;  1EF8 A;  4FJW D;  4JWV A;  2GTR A;  3MOY A;  4K3W A;  4WCZ A;  2FW2 A;  3Q0J A;  4JYL A;  4IZD A;  3IRB A;  4GEH B;  4K2N A;  1DCI A;  1Y64 B;  3A4N A;  3P5M A;  4KNP A;  4I42 A;  4IZB A;  4FZW A;  4IZC A;  4U18 A;  3Q0G A;  1RJN A;  3MYB A;  3O4X E;  5JBW A;  5C9G A;  4I52 A;  4OG1 A;  1Q51 A;  2VX2 A;  3L8I A;  3RQE A;  1UX4 A;  3HIN A;  3HRX A;  1NZY B;  2ZQQ A;  3KQF A;  3W8I B;  1HZD A;  3SWX A;  2F6Q A;  3OC7 A;  2ZQR A;  4QII A;  4U19 A;  4ELX A;  4FZW C;  3ADC A;  2P63 A;  2HW5 A;  2FBM A;  3W8H B;  3QXZ A;  3T88 A;  3FDU A;  4MI2 A;  3H81 A;  3QXI A;  1NZY A;  3R9T A;  3T89 A;  4EML A;  3A4M A;  3T8A A;  3AJM A;  4OLQ A;  3R0O A;  1EY3 A;  2PPY A;  3R9S A;  1DUB A;  3TRR A;  3H02 A;  1UIY A;  4JFC A;  4ZU2 A;  3I47 A;  1JXZ A;  3TLF A;  1MJ3 A;  3QK8 A;  3RQG A;  4QIJ A;  4U1A A;  2UZF A;  1RJM A;  2EJ5 A;  3A4L A;  4I4Z A;  5KJP A;  1Q52 A;  4F47 A;  3AM1 A;  4MOU A;  3Q1T A;  2DUB A;  3PZK A;  4ELS A; 
#chains in the Genus database with same CATH homology
 3IRB A;  3A4M A;  4GEH B;  3AJM A;  3L8J A;  3ADD A;  1Y64 B;  3A4N A;  3W8I B;  1UX5 A;  3ADB A;  3ADC A;  2P63 A;  4NNQ A;  3RQG A;  3W8H B;  3RQF A;  1RJM A;  3O4X E;  3A4L A;  3L8I A;  3RQE A;  1UX4 A;  3AM1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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