1GIQA

Crystal structure of the enzymatic componet of iota-toxin from clostridium perfringens with nadh
Total Genus 133
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
133
sequence length
411
structure length
411
Chain Sequence
IERPEDFLKDKENAIQWEKKEAERVEKNLDTLEKEALELYKKDSEQISNYSQTRQYFYDYQIESNPREKEYKNLRNAISKNKIDKPINVYYFESPEKFAFNKEIRTENQNEISLEKFNELKETIQDKLFKQDGFKDVSLYEPGNGDEKPTPLLIHLKLPKNTGMLPYINSNDVKTLIEQDYSIKIDKIVRIVIEGKQYIKAEASIVNSLDFKDDVSKGDLWGKENYSDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPLNNPNPELDSKVNNIENALKLTPIPSNLIVYRRSGPQEFGLTLTSPEYDFNKIENIDAFKEKWEGKVITYPNFISTSIGSVNMSAFAKRKIILRINIPKDSPGAYLSAIPGYAGEYEVLLNHGSKFKINKVDSYKDGTVTKLILDATLIN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure and Site-directed Mutagenesis of Enzymatic Components from Clostridium perfringens Iota-toxin
pubmed doi rcsb
molecule tags Toxin
molecule keywords IOTA TOXIN COMPONENT IA
total genus 133
structure length 411
sequence length 411
chains with identical sequence B
ec nomenclature
pdb deposition date 2001-03-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 1giqA02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 1giqA01
4PKSA 1GIQA 1GZEA 4PKUA 5H03A 4PKVA 1OG4A 1QS2A 2C8DA 2A9KB 3BUZA 1PWVA 1OJQA 4XM7A 3BW8A 5DZQA 4H0XA 2C8HA 4XM8A 2C8GA 2C8FE 2J3VA 3NTSA 4H03A 1YQYA 4H0TA 4PKTA 2J3XA 4H0YA 1GXYA 1R4BA 2WN4A 4FMLA 1UZIA 2C8AA 2WN5A 2J3ZA 2WN8A 5H04A 1GY0A 5D1TA 2WN6A 1JKYA 5BWMB 4XM6A 4GY2A 2BOVB 1R45A 4PKWA 4FK7A 1GIRA 2C8EE 5D1SA 4ELNA 1OG1A 4DV8A 2C8CA 4FXQA 4PKRA 1PWUA 1GXZA 1PWPA 2GWMA 1QS1A 1J7NA 4TR5A 2C8BX 1GZFA 2A78B 1PWQA 3U0JA 4PKQA 5GTTA 4XSGB 1PWWA 1ZXVA 2GWLA 4GF1A 1OG3A 2C89A 1G24A 4H0VA 4XSHB 5D1UA 1OJZA 2WN7A 4WF6A
chains in the Genus database with same CATH superfamily
4PKSA 1GIQA 1GZEA 4PKUA 5H03A 4PKVA 1OG4A 1QS2A 2C8DA 2A9KB 3BUZA 1PWVA 1OJQA 4XM7A 3BW8A 5DZQA 4H0XA 2C8HA 4XM8A 2C8GA 2C8FE 2J3VA 3NTSA 4H03A 1YQYA 4H0TA 4PKTA 2J3XA 4H0YA 1GXYA 1R4BA 2WN4A 4FMLA 1UZIA 2C8AA 2WN5A 2J3ZA 2WN8A 5H04A 1GY0A 5D1TA 2WN6A 1JKYA 5BWMB 4XM6A 4GY2A 2BOVB 1R45A 4PKWA 4FK7A 1GIRA 2C8EE 5D1SA 4ELNA 1OG1A 4DV8A 2C8CA 4FXQA 4PKRA 1PWUA 1GXZA 1PWPA 2GWMA 1QS1A 1J7NA 4TR5A 2C8BX 1GZFA 2A78B 1PWQA 3U0JA 4PKQA 5GTTA 4XSGB 1PWWA 1ZXVA 2GWLA 4GF1A 1OG3A 2C89A 1G24A 4H0VA 4XSHB 5D1UA 1OJZA 2WN7A 4WF6A
chains in the Genus database with same CATH topology
4PKSA 1GIQA 1GZEA 4PKUA 5H03A 4PKVA 1OG4A 1QS2A 2C8DA 2A9KB 3BUZA 1PWVA 1OJQA 4XM7A 3BW8A 5DZQA 4H0XA 2C8HA 4XM8A 2C8GA 2C8FE 2J3VA 3NTSA 4H03A 1YQYA 4H0TA 4PKTA 2J3XA 4H0YA 1GXYA 1R4BA 2WN4A 4FMLA 1UZIA 2C8AA 2WN5A 2J3ZA 2WN8A 5H04A 1GY0A 5D1TA 2WN6A 1JKYA 5BWMB 4XM6A 4GY2A 2BOVB 1R45A 4PKWA 4FK7A 1GIRA 2C8EE 5D1SA 4ELNA 1OG1A 4DV8A 2C8CA 4FXQA 4PKRA 1PWUA 1GXZA 1PWPA 2GWMA 1QS1A 1J7NA 4TR5A 2C8BX 1GZFA 2A78B 1PWQA 3U0JA 4PKQA 5GTTA 4XSGB 1PWWA 1ZXVA 2GWLA 4GF1A 1OG3A 2C89A 1G24A 4H0VA 4XSHB 5D1UA 1OJZA 2WN7A 4WF6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PKS A;  1GIQ A;  1GZE A;  4PKU A;  5H03 A;  4PKV A;  1OG4 A;  1QS2 A;  2C8D A;  2A9K B;  3BUZ A;  1PWV A;  1OJQ A;  4XM7 A;  3BW8 A;  5DZQ A;  4H0X A;  2C8H A;  4XM8 A;  2C8G A;  2C8F E;  2J3V A;  3NTS A;  4H03 A;  1YQY A;  4H0T A;  4PKT A;  2J3X A;  4H0Y A;  1GXY A;  1R4B A;  2WN4 A;  4FML A;  1UZI A;  2C8A A;  2WN5 A;  2J3Z A;  2WN8 A;  5H04 A;  1GY0 A;  5D1T A;  2WN6 A;  1JKY A;  5BWM B;  4XM6 A;  4GY2 A;  2BOV B;  1R45 A;  4PKW A;  4FK7 A;  1GIR A;  2C8E E;  5D1S A;  4ELN A;  1OG1 A;  4DV8 A;  2C8C A;  4FXQ A;  4PKR A;  1PWU A;  1GXZ A;  1PWP A;  2GWM A;  1QS1 A;  1J7N A;  4TR5 A;  2C8B X;  1GZF A;  2A78 B;  1PWQ A;  3U0J A;  4PKQ A;  5GTT A;  4XSG B;  1PWW A;  1ZXV A;  2GWL A;  4GF1 A;  1OG3 A;  2C89 A;  1G24 A;  4H0V A;  4XSH B;  5D1U A;  1OJZ A;  2WN7 A;  4WF6 A; 
#chains in the Genus database with same CATH topology
 4PKS A;  1GIQ A;  1GZE A;  4PKU A;  5H03 A;  4PKV A;  1OG4 A;  1QS2 A;  2C8D A;  2A9K B;  3BUZ A;  1PWV A;  1OJQ A;  4XM7 A;  3BW8 A;  5DZQ A;  4H0X A;  2C8H A;  4XM8 A;  2C8G A;  2C8F E;  2J3V A;  3NTS A;  4H03 A;  1YQY A;  4H0T A;  4PKT A;  2J3X A;  4H0Y A;  1GXY A;  1R4B A;  2WN4 A;  4FML A;  1UZI A;  2C8A A;  2WN5 A;  2J3Z A;  2WN8 A;  5H04 A;  1GY0 A;  5D1T A;  2WN6 A;  1JKY A;  5BWM B;  4XM6 A;  4GY2 A;  2BOV B;  1R45 A;  4PKW A;  4FK7 A;  1GIR A;  2C8E E;  5D1S A;  4ELN A;  1OG1 A;  4DV8 A;  2C8C A;  4FXQ A;  4PKR A;  1PWU A;  1GXZ A;  1PWP A;  2GWM A;  1QS1 A;  1J7N A;  4TR5 A;  2C8B X;  1GZF A;  2A78 B;  1PWQ A;  3U0J A;  4PKQ A;  5GTT A;  4XSG B;  1PWW A;  1ZXV A;  2GWL A;  4GF1 A;  1OG3 A;  2C89 A;  1G24 A;  4H0V A;  4XSH B;  5D1U A;  1OJZ A;  2WN7 A;  4WF6 A; 
#chains in the Genus database with same CATH homology
 4PKS A;  1GIQ A;  1GZE A;  4PKU A;  5H03 A;  4PKV A;  1OG4 A;  1QS2 A;  2C8D A;  2A9K B;  3BUZ A;  1PWV A;  1OJQ A;  4XM7 A;  3BW8 A;  5DZQ A;  4H0X A;  2C8H A;  4XM8 A;  2C8G A;  2C8F E;  2J3V A;  3NTS A;  4H03 A;  1YQY A;  4H0T A;  4PKT A;  2J3X A;  4H0Y A;  1GXY A;  1R4B A;  2WN4 A;  4FML A;  1UZI A;  2C8A A;  2WN5 A;  2J3Z A;  2WN8 A;  5H04 A;  1GY0 A;  5D1T A;  2WN6 A;  1JKY A;  5BWM B;  4XM6 A;  4GY2 A;  2BOV B;  1R45 A;  4PKW A;  4FK7 A;  1GIR A;  2C8E E;  5D1S A;  4ELN A;  1OG1 A;  4DV8 A;  2C8C A;  4FXQ A;  4PKR A;  1PWU A;  1GXZ A;  1PWP A;  2GWM A;  1QS1 A;  1J7N A;  4TR5 A;  2C8B X;  1GZF A;  2A78 B;  1PWQ A;  3U0J A;  4PKQ A;  5GTT A;  4XSG B;  1PWW A;  1ZXV A;  2GWL A;  4GF1 A;  1OG3 A;  2C89 A;  1G24 A;  4H0V A;  4XSH B;  5D1U A;  1OJZ A;  2WN7 A;  4WF6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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