2WN8A

Structural basis for substrate recognition in the enzymatic component of adp-ribosyltransferase toxin cdta from clostridium difficile
Total Genus 125
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
125
sequence length
396
structure length
389
Chain Sequence
EWERKEAERIEQKLERSEKEALESYKKDSVEISKYSQTRNYFYDYQIEANSREKEYKELRNAISKNKIDKPMYVYYFESPEKFAFNKVIRTENQNEISLEKFNEFKETIQNKLFKQDGFKDISLYEPGKGDEKPTPLLMHLKLPRNTGMLPYTVSTLIEQGYSIKIDKIVRIVIDGKHYIKAEASVVSSLDFKDDVSKGDSWGKANYNDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPVNNPNPELDSKITNIENALKREPIPTNLTVYRRSGPQEFGLTLTSPEYDFNKLENIDAFKSKWEGQALSYPNFISTSIGSVNMSAFAKRKIVLRITIPKGSPGAYLSAIPGEYEVLLNHGSKFKINKIDSYKDGTITKLIVDATLIP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords ADP-RIBOSYLTRANSFERASE ENZYMATIC COMPONENT
publication title Structural Basis for Substrate Recognition in the Enzymatic Component of Adp-Ribosyltransferase Toxin Cdta from Clostridium Difficile.
pubmed doi rcsb
source organism Clostridium difficile
molecule tags Transferase
total genus 125
structure length 389
sequence length 396
ec nomenclature
pdb deposition date 2009-07-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2wn8A02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2wn8A01
1R45A 2C8CA 4XM6A 2A9KB 4XM7A 1PWQA 3U0JA 2GWMA 1ZXVA 4H0TA 4GY2A 1QS2A 1PWPA 1R4BA 2J3ZA 4PKUA 4ELNA 4H0YA 1G24A 1OJZA 1GIRA 3BW8A 4GF1A 1GIQA 1YQYA 2C8GA 4FMLA 5BWMB 4WF6A 2WN4A 4H0VA 4DV8A 5D1TA 2WN5A 1UZIA 4H03A 2C8HA 4PKVA 4H0XA 1GXYA 5D1UA 3NTSA 5H04A 1QS1A 4TR5A 1GZFA 5D1SA 5DZQA 4PKRA 4PKSA 5H03A 2WN7A 2C8AA 1OJQA 1GXZA 2A78B 4PKQA 4XSGB 1PWVA 2J3VA 2C8FE 4XSHB 4FK7A 2C89A 1PWWA 2C8EE 2WN6A 4PKTA 4PKWA 1OG1A 3BUZA 4FXQA 2WN8A 2J3XA 2BOVB 5GTTA 2GWLA 1PWUA 1JKYA 1OG4A 1GY0A 2C8DA 2C8BX 1J7NA 1OG3A 4XM8A 1GZEA
chains in the Genus database with same CATH superfamily
1R45A 2C8CA 4XM6A 2A9KB 4XM7A 1PWQA 3U0JA 2GWMA 1ZXVA 4H0TA 4GY2A 1QS2A 1PWPA 1R4BA 2J3ZA 4PKUA 4ELNA 4H0YA 1G24A 1OJZA 1GIRA 3BW8A 4GF1A 1GIQA 1YQYA 2C8GA 4FMLA 5BWMB 4WF6A 2WN4A 4H0VA 4DV8A 5D1TA 2WN5A 1UZIA 4H03A 2C8HA 4PKVA 4H0XA 1GXYA 5D1UA 3NTSA 5H04A 1QS1A 4TR5A 1GZFA 5D1SA 5DZQA 4PKRA 4PKSA 5H03A 2WN7A 2C8AA 1OJQA 1GXZA 2A78B 4PKQA 4XSGB 1PWVA 2J3VA 2C8FE 4XSHB 4FK7A 2C89A 1PWWA 2C8EE 2WN6A 4PKTA 4PKWA 1OG1A 3BUZA 4FXQA 2WN8A 2J3XA 2BOVB 5GTTA 2GWLA 1PWUA 1JKYA 1OG4A 1GY0A 2C8DA 2C8BX 1J7NA 1OG3A 4XM8A 1GZEA
chains in the Genus database with same CATH topology
1R45A 2C8CA 4XM6A 2A9KB 4XM7A 1PWQA 3U0JA 2GWMA 1ZXVA 4H0TA 4GY2A 1QS2A 1PWPA 1R4BA 2J3ZA 4PKUA 4ELNA 4H0YA 1G24A 1OJZA 1GIRA 3BW8A 4GF1A 1GIQA 1YQYA 2C8GA 4FMLA 5BWMB 4WF6A 2WN4A 4H0VA 4DV8A 5D1TA 2WN5A 1UZIA 4H03A 2C8HA 4PKVA 4H0XA 1GXYA 5D1UA 3NTSA 5H04A 1QS1A 4TR5A 1GZFA 5D1SA 5DZQA 4PKRA 4PKSA 5H03A 2WN7A 2C8AA 1OJQA 1GXZA 2A78B 4PKQA 4XSGB 1PWVA 2J3VA 2C8FE 4XSHB 4FK7A 2C89A 1PWWA 2C8EE 2WN6A 4PKTA 4PKWA 1OG1A 3BUZA 4FXQA 2WN8A 2J3XA 2BOVB 5GTTA 2GWLA 1PWUA 1JKYA 1OG4A 1GY0A 2C8DA 2C8BX 1J7NA 1OG3A 4XM8A 1GZEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1R45 A;  2C8C A;  4XM6 A;  2A9K B;  4XM7 A;  1PWQ A;  3U0J A;  2GWM A;  1ZXV A;  4H0T A;  4GY2 A;  1QS2 A;  1PWP A;  1R4B A;  2J3Z A;  4PKU A;  4ELN A;  4H0Y A;  1G24 A;  1OJZ A;  1GIR A;  3BW8 A;  4GF1 A;  1GIQ A;  1YQY A;  2C8G A;  4FML A;  5BWM B;  4WF6 A;  2WN4 A;  4H0V A;  4DV8 A;  5D1T A;  2WN5 A;  1UZI A;  4H03 A;  2C8H A;  4PKV A;  4H0X A;  1GXY A;  5D1U A;  3NTS A;  5H04 A;  1QS1 A;  4TR5 A;  1GZF A;  5D1S A;  5DZQ A;  4PKR A;  4PKS A;  5H03 A;  2WN7 A;  2C8A A;  1OJQ A;  1GXZ A;  2A78 B;  4PKQ A;  4XSG B;  1PWV A;  2J3V A;  2C8F E;  4XSH B;  4FK7 A;  2C89 A;  1PWW A;  2C8E E;  2WN6 A;  4PKT A;  4PKW A;  1OG1 A;  3BUZ A;  4FXQ A;  2WN8 A;  2J3X A;  2BOV B;  5GTT A;  2GWL A;  1PWU A;  1JKY A;  1OG4 A;  1GY0 A;  2C8D A;  2C8B X;  1J7N A;  1OG3 A;  4XM8 A;  1GZE A; 
#chains in the Genus database with same CATH topology
 1R45 A;  2C8C A;  4XM6 A;  2A9K B;  4XM7 A;  1PWQ A;  3U0J A;  2GWM A;  1ZXV A;  4H0T A;  4GY2 A;  1QS2 A;  1PWP A;  1R4B A;  2J3Z A;  4PKU A;  4ELN A;  4H0Y A;  1G24 A;  1OJZ A;  1GIR A;  3BW8 A;  4GF1 A;  1GIQ A;  1YQY A;  2C8G A;  4FML A;  5BWM B;  4WF6 A;  2WN4 A;  4H0V A;  4DV8 A;  5D1T A;  2WN5 A;  1UZI A;  4H03 A;  2C8H A;  4PKV A;  4H0X A;  1GXY A;  5D1U A;  3NTS A;  5H04 A;  1QS1 A;  4TR5 A;  1GZF A;  5D1S A;  5DZQ A;  4PKR A;  4PKS A;  5H03 A;  2WN7 A;  2C8A A;  1OJQ A;  1GXZ A;  2A78 B;  4PKQ A;  4XSG B;  1PWV A;  2J3V A;  2C8F E;  4XSH B;  4FK7 A;  2C89 A;  1PWW A;  2C8E E;  2WN6 A;  4PKT A;  4PKW A;  1OG1 A;  3BUZ A;  4FXQ A;  2WN8 A;  2J3X A;  2BOV B;  5GTT A;  2GWL A;  1PWU A;  1JKY A;  1OG4 A;  1GY0 A;  2C8D A;  2C8B X;  1J7N A;  1OG3 A;  4XM8 A;  1GZE A; 
#chains in the Genus database with same CATH homology
 1R45 A;  2C8C A;  4XM6 A;  2A9K B;  4XM7 A;  1PWQ A;  3U0J A;  2GWM A;  1ZXV A;  4H0T A;  4GY2 A;  1QS2 A;  1PWP A;  1R4B A;  2J3Z A;  4PKU A;  4ELN A;  4H0Y A;  1G24 A;  1OJZ A;  1GIR A;  3BW8 A;  4GF1 A;  1GIQ A;  1YQY A;  2C8G A;  4FML A;  5BWM B;  4WF6 A;  2WN4 A;  4H0V A;  4DV8 A;  5D1T A;  2WN5 A;  1UZI A;  4H03 A;  2C8H A;  4PKV A;  4H0X A;  1GXY A;  5D1U A;  3NTS A;  5H04 A;  1QS1 A;  4TR5 A;  1GZF A;  5D1S A;  5DZQ A;  4PKR A;  4PKS A;  5H03 A;  2WN7 A;  2C8A A;  1OJQ A;  1GXZ A;  2A78 B;  4PKQ A;  4XSG B;  1PWV A;  2J3V A;  2C8F E;  4XSH B;  4FK7 A;  2C89 A;  1PWW A;  2C8E E;  2WN6 A;  4PKT A;  4PKW A;  1OG1 A;  3BUZ A;  4FXQ A;  2WN8 A;  2J3X A;  2BOV B;  5GTT A;  2GWL A;  1PWU A;  1JKY A;  1OG4 A;  1GY0 A;  2C8D A;  2C8B X;  1J7N A;  1OG3 A;  4XM8 A;  1GZE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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