2WN8A

Structural basis for substrate recognition in the enzymatic component of adp-ribosyltransferase toxin cdta from clostridium difficile
Total Genus 125
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
125
sequence length
396
structure length
389
Chain Sequence
EWERKEAERIEQKLERSEKEALESYKKDSVEISKYSQTRNYFYDYQIEANSREKEYKELRNAISKNKIDKPMYVYYFESPEKFAFNKVIRTENQNEISLEKFNEFKETIQNKLFKQDGFKDISLYEPGKGDEKPTPLLMHLKLPRNTGMLPYTVSTLIEQGYSIKIDKIVRIVIDGKHYIKAEASVVSSLDFKDDVSKGDSWGKANYNDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPVNNPNPELDSKITNIENALKREPIPTNLTVYRRSGPQEFGLTLTSPEYDFNKLENIDAFKSKWEGQALSYPNFISTSIGSVNMSAFAKRKIVLRITIPKGSPGAYLSAIPGEYEVLLNHGSKFKINKIDSYKDGTITKLIVDATLIP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords ADP-RIBOSYLTRANSFERASE ENZYMATIC COMPONENT
publication title Structural Basis for Substrate Recognition in the Enzymatic Component of Adp-Ribosyltransferase Toxin Cdta from Clostridium Difficile.
pubmed doi rcsb
source organism Clostridium difficile
total genus 125
structure length 389
sequence length 396
ec nomenclature
pdb deposition date 2009-07-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2wn8A02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2wn8A01
4H0YA 4XSHB 1GZEA 4GF1A 1OJZA 2C8CA 2J3XA 2C8EE 4TR5A 1PWVA 2A78B 1YQYA 5DZQA 2C89A 2C8GA 1GIQA 4FXQA 1QS2A 4GY2A 1GXZA 4FMLA 2J3ZA 1PWPA 2WN6A 5H04A 2C8BX 1J7NA 3BUZA 4H0TA 4PKTA 4PKVA 5D1SA 5BWMB 4H0VA 5D1TA 4DV8A 1OG1A 2C8AA 1OJQA 4WF6A 1OG4A 5H03A 1G24A 1ZXVA 2WN7A 4ELNA 4PKUA 1OG3A 2BOVB 2WN5A 4XSGB 3BW8A 1GXYA 1GZFA 1R45A 4H0XA 1QS1A 1PWQA 2GWMA 2A9KB 3NTSA 4XM7A 2GWLA 4FK7A 2C8DA 1PWUA 1UZIA 4XM6A 5D1UA 2C8HA 3U0JA 2C8FE 4H03A 1JKYA 4PKSA 2J3VA 1GY0A 4PKWA 5GTTA 4PKRA 1PWWA 2WN4A 4PKQA 2WN8A 1GIRA 1R4BA 4XM8A
chains in the Genus database with same CATH superfamily
4H0YA 4XSHB 1GZEA 4GF1A 1OJZA 2C8CA 2J3XA 2C8EE 4TR5A 1PWVA 2A78B 1YQYA 5DZQA 2C89A 2C8GA 1GIQA 4FXQA 1QS2A 4GY2A 1GXZA 4FMLA 2J3ZA 1PWPA 2WN6A 5H04A 2C8BX 1J7NA 3BUZA 4H0TA 4PKTA 4PKVA 5D1SA 5BWMB 4H0VA 5D1TA 4DV8A 1OG1A 2C8AA 1OJQA 4WF6A 1OG4A 5H03A 1G24A 1ZXVA 2WN7A 4ELNA 4PKUA 1OG3A 2BOVB 2WN5A 4XSGB 3BW8A 1GXYA 1GZFA 1R45A 4H0XA 1QS1A 1PWQA 2GWMA 2A9KB 3NTSA 4XM7A 2GWLA 4FK7A 2C8DA 1PWUA 1UZIA 4XM6A 5D1UA 2C8HA 3U0JA 2C8FE 4H03A 1JKYA 4PKSA 2J3VA 1GY0A 4PKWA 5GTTA 4PKRA 1PWWA 2WN4A 4PKQA 2WN8A 1GIRA 1R4BA 4XM8A
chains in the Genus database with same CATH topology
4H0YA 4XSHB 1GZEA 4GF1A 1OJZA 2C8CA 2J3XA 2C8EE 4TR5A 1PWVA 2A78B 1YQYA 5DZQA 2C89A 2C8GA 1GIQA 4FXQA 1QS2A 4GY2A 1GXZA 4FMLA 2J3ZA 1PWPA 2WN6A 5H04A 2C8BX 1J7NA 3BUZA 4H0TA 4PKTA 4PKVA 5D1SA 5BWMB 4H0VA 5D1TA 4DV8A 1OG1A 2C8AA 1OJQA 4WF6A 1OG4A 5H03A 1G24A 1ZXVA 2WN7A 4ELNA 4PKUA 1OG3A 2BOVB 2WN5A 4XSGB 3BW8A 1GXYA 1GZFA 1R45A 4H0XA 1QS1A 1PWQA 2GWMA 2A9KB 3NTSA 4XM7A 2GWLA 4FK7A 2C8DA 1PWUA 1UZIA 4XM6A 5D1UA 2C8HA 3U0JA 2C8FE 4H03A 1JKYA 4PKSA 2J3VA 1GY0A 4PKWA 5GTTA 4PKRA 1PWWA 2WN4A 4PKQA 2WN8A 1GIRA 1R4BA 4XM8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4H0Y A;  4XSH B;  1GZE A;  4GF1 A;  1OJZ A;  2C8C A;  2J3X A;  2C8E E;  4TR5 A;  1PWV A;  2A78 B;  1YQY A;  5DZQ A;  2C89 A;  2C8G A;  1GIQ A;  4FXQ A;  1QS2 A;  4GY2 A;  1GXZ A;  4FML A;  2J3Z A;  1PWP A;  2WN6 A;  5H04 A;  2C8B X;  1J7N A;  3BUZ A;  4H0T A;  4PKT A;  4PKV A;  5D1S A;  5BWM B;  4H0V A;  5D1T A;  4DV8 A;  1OG1 A;  2C8A A;  1OJQ A;  4WF6 A;  1OG4 A;  5H03 A;  1G24 A;  1ZXV A;  2WN7 A;  4ELN A;  4PKU A;  1OG3 A;  2BOV B;  2WN5 A;  4XSG B;  3BW8 A;  1GXY A;  1GZF A;  1R45 A;  4H0X A;  1QS1 A;  1PWQ A;  2GWM A;  2A9K B;  3NTS A;  4XM7 A;  2GWL A;  4FK7 A;  2C8D A;  1PWU A;  1UZI A;  4XM6 A;  5D1U A;  2C8H A;  3U0J A;  2C8F E;  4H03 A;  1JKY A;  4PKS A;  2J3V A;  1GY0 A;  4PKW A;  5GTT A;  4PKR A;  1PWW A;  2WN4 A;  4PKQ A;  2WN8 A;  1GIR A;  1R4B A;  4XM8 A; 
#chains in the Genus database with same CATH topology
 4H0Y A;  4XSH B;  1GZE A;  4GF1 A;  1OJZ A;  2C8C A;  2J3X A;  2C8E E;  4TR5 A;  1PWV A;  2A78 B;  1YQY A;  5DZQ A;  2C89 A;  2C8G A;  1GIQ A;  4FXQ A;  1QS2 A;  4GY2 A;  1GXZ A;  4FML A;  2J3Z A;  1PWP A;  2WN6 A;  5H04 A;  2C8B X;  1J7N A;  3BUZ A;  4H0T A;  4PKT A;  4PKV A;  5D1S A;  5BWM B;  4H0V A;  5D1T A;  4DV8 A;  1OG1 A;  2C8A A;  1OJQ A;  4WF6 A;  1OG4 A;  5H03 A;  1G24 A;  1ZXV A;  2WN7 A;  4ELN A;  4PKU A;  1OG3 A;  2BOV B;  2WN5 A;  4XSG B;  3BW8 A;  1GXY A;  1GZF A;  1R45 A;  4H0X A;  1QS1 A;  1PWQ A;  2GWM A;  2A9K B;  3NTS A;  4XM7 A;  2GWL A;  4FK7 A;  2C8D A;  1PWU A;  1UZI A;  4XM6 A;  5D1U A;  2C8H A;  3U0J A;  2C8F E;  4H03 A;  1JKY A;  4PKS A;  2J3V A;  1GY0 A;  4PKW A;  5GTT A;  4PKR A;  1PWW A;  2WN4 A;  4PKQ A;  2WN8 A;  1GIR A;  1R4B A;  4XM8 A; 
#chains in the Genus database with same CATH homology
 4H0Y A;  4XSH B;  1GZE A;  4GF1 A;  1OJZ A;  2C8C A;  2J3X A;  2C8E E;  4TR5 A;  1PWV A;  2A78 B;  1YQY A;  5DZQ A;  2C89 A;  2C8G A;  1GIQ A;  4FXQ A;  1QS2 A;  4GY2 A;  1GXZ A;  4FML A;  2J3Z A;  1PWP A;  2WN6 A;  5H04 A;  2C8B X;  1J7N A;  3BUZ A;  4H0T A;  4PKT A;  4PKV A;  5D1S A;  5BWM B;  4H0V A;  5D1T A;  4DV8 A;  1OG1 A;  2C8A A;  1OJQ A;  4WF6 A;  1OG4 A;  5H03 A;  1G24 A;  1ZXV A;  2WN7 A;  4ELN A;  4PKU A;  1OG3 A;  2BOV B;  2WN5 A;  4XSG B;  3BW8 A;  1GXY A;  1GZF A;  1R45 A;  4H0X A;  1QS1 A;  1PWQ A;  2GWM A;  2A9K B;  3NTS A;  4XM7 A;  2GWL A;  4FK7 A;  2C8D A;  1PWU A;  1UZI A;  4XM6 A;  5D1U A;  2C8H A;  3U0J A;  2C8F E;  4H03 A;  1JKY A;  4PKS A;  2J3V A;  1GY0 A;  4PKW A;  5GTT A;  4PKR A;  1PWW A;  2WN4 A;  4PKQ A;  2WN8 A;  1GIR A;  1R4B A;  4XM8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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