2WN5A

Structural basis for substrate recognition in the enzymatic component of adp-ribosyltransferase toxin cdta from clostridium difficile
Total Genus 132
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
132
sequence length
397
structure length
394
Chain Sequence
KEWERKEAERIEQKLERSEKEALESYKKDSVEISKYSQTRNYFYDYQIEANSREKEYKELRNAISKNKIDKPMYVYYFESPEKFAFNKVIRTENQNEISLEKFNEFKETIQNKLFKQDGFKDISLYEPGKGDEKPTPLLMHLKLPRNTGMLPYTNNNVSTLIEQGYSIKIDKIVRIVIDGKHYIKAEASVVSSLDFKDDVSKGDSWGKANYNDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPVNNPNPELDSKITNIENALKREPIPTNLTVYRRSGPQEFGLTLTSPEYDFNKLENIDAFKSKWEGQALSYPNFISTSIGSVNMSAFAKRKIVLRITIPKGSPGAYLSAIPGYEYEVLLNHGSKFKINKIDSYKDGTITKLIVDATLIP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords ADP-RIBOSYLTRANSFERASE ENZYMATIC COMPONENT
publication title Structural Basis for Substrate Recognition in the Enzymatic Component of Adp-Ribosyltransferase Toxin Cdta from Clostridium Difficile.
pubmed doi rcsb
source organism Clostridium difficile
molecule tags Transferase
total genus 132
structure length 394
sequence length 397
ec nomenclature
pdb deposition date 2009-07-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2wn5A02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2wn5A01
2C89A 4FMLA 2A78B 4PKSA 1PWWA 4ELNA 2J3ZA 5H03A 4XSHB 4H0YA 4TR5A 1JKYA 2C8AA 1UZIA 4WF6A 1OJQA 4PKUA 4PKWA 3BUZA 1GIQA 4PKQA 1R45A 4XM6A 2C8CA 1OJZA 1YQYA 4PKTA 3BW8A 4H03A 2BOVB 2GWLA 2J3VA 4DV8A 4XM7A 1GIRA 2J3XA 4H0XA 1OG3A 1R4BA 3NTSA 4PKRA 2C8DA 2WN7A 5D1SA 4PKVA 1OG4A 2WN8A 2C8FE 5GTTA 5DZQA 1GZEA 2WN6A 2C8EE 4XM8A 4H0TA 2C8BX 5D1TA 2WN4A 5H04A 4GY2A 5D1UA 1GZFA 1QS2A 2GWMA 1GXYA 1PWVA 1G24A 1GY0A 1OG1A 1GXZA 5BWMB 4GF1A 2C8HA 4FK7A 1PWQA 1PWPA 4FXQA 1PWUA 2WN5A 4H0VA 1J7NA 1QS1A 3U0JA 4XSGB 1ZXVA 2A9KB 2C8GA
chains in the Genus database with same CATH superfamily
2C89A 4FMLA 2A78B 4PKSA 1PWWA 4ELNA 2J3ZA 5H03A 4XSHB 4H0YA 4TR5A 1JKYA 2C8AA 1UZIA 4WF6A 1OJQA 4PKUA 4PKWA 3BUZA 1GIQA 4PKQA 1R45A 4XM6A 2C8CA 1OJZA 1YQYA 4PKTA 3BW8A 4H03A 2BOVB 2GWLA 2J3VA 4DV8A 4XM7A 1GIRA 2J3XA 4H0XA 1OG3A 1R4BA 3NTSA 4PKRA 2C8DA 2WN7A 5D1SA 4PKVA 1OG4A 2WN8A 2C8FE 5GTTA 5DZQA 1GZEA 2WN6A 2C8EE 4XM8A 4H0TA 2C8BX 5D1TA 2WN4A 5H04A 4GY2A 5D1UA 1GZFA 1QS2A 2GWMA 1GXYA 1PWVA 1G24A 1GY0A 1OG1A 1GXZA 5BWMB 4GF1A 2C8HA 4FK7A 1PWQA 1PWPA 4FXQA 1PWUA 2WN5A 4H0VA 1J7NA 1QS1A 3U0JA 4XSGB 1ZXVA 2A9KB 2C8GA
chains in the Genus database with same CATH topology
2C89A 4FMLA 2A78B 4PKSA 1PWWA 4ELNA 2J3ZA 5H03A 4XSHB 4H0YA 4TR5A 1JKYA 2C8AA 1UZIA 4WF6A 1OJQA 4PKUA 4PKWA 3BUZA 1GIQA 4PKQA 1R45A 4XM6A 2C8CA 1OJZA 1YQYA 4PKTA 3BW8A 4H03A 2BOVB 2GWLA 2J3VA 4DV8A 4XM7A 1GIRA 2J3XA 4H0XA 1OG3A 1R4BA 3NTSA 4PKRA 2C8DA 2WN7A 5D1SA 4PKVA 1OG4A 2WN8A 2C8FE 5GTTA 5DZQA 1GZEA 2WN6A 2C8EE 4XM8A 4H0TA 2C8BX 5D1TA 2WN4A 5H04A 4GY2A 5D1UA 1GZFA 1QS2A 2GWMA 1GXYA 1PWVA 1G24A 1GY0A 1OG1A 1GXZA 5BWMB 4GF1A 2C8HA 4FK7A 1PWQA 1PWPA 4FXQA 1PWUA 2WN5A 4H0VA 1J7NA 1QS1A 3U0JA 4XSGB 1ZXVA 2A9KB 2C8GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2C89 A;  4FML A;  2A78 B;  4PKS A;  1PWW A;  4ELN A;  2J3Z A;  5H03 A;  4XSH B;  4H0Y A;  4TR5 A;  1JKY A;  2C8A A;  1UZI A;  4WF6 A;  1OJQ A;  4PKU A;  4PKW A;  3BUZ A;  1GIQ A;  4PKQ A;  1R45 A;  4XM6 A;  2C8C A;  1OJZ A;  1YQY A;  4PKT A;  3BW8 A;  4H03 A;  2BOV B;  2GWL A;  2J3V A;  4DV8 A;  4XM7 A;  1GIR A;  2J3X A;  4H0X A;  1OG3 A;  1R4B A;  3NTS A;  4PKR A;  2C8D A;  2WN7 A;  5D1S A;  4PKV A;  1OG4 A;  2WN8 A;  2C8F E;  5GTT A;  5DZQ A;  1GZE A;  2WN6 A;  2C8E E;  4XM8 A;  4H0T A;  2C8B X;  5D1T A;  2WN4 A;  5H04 A;  4GY2 A;  5D1U A;  1GZF A;  1QS2 A;  2GWM A;  1GXY A;  1PWV A;  1G24 A;  1GY0 A;  1OG1 A;  1GXZ A;  5BWM B;  4GF1 A;  2C8H A;  4FK7 A;  1PWQ A;  1PWP A;  4FXQ A;  1PWU A;  2WN5 A;  4H0V A;  1J7N A;  1QS1 A;  3U0J A;  4XSG B;  1ZXV A;  2A9K B;  2C8G A; 
#chains in the Genus database with same CATH topology
 2C89 A;  4FML A;  2A78 B;  4PKS A;  1PWW A;  4ELN A;  2J3Z A;  5H03 A;  4XSH B;  4H0Y A;  4TR5 A;  1JKY A;  2C8A A;  1UZI A;  4WF6 A;  1OJQ A;  4PKU A;  4PKW A;  3BUZ A;  1GIQ A;  4PKQ A;  1R45 A;  4XM6 A;  2C8C A;  1OJZ A;  1YQY A;  4PKT A;  3BW8 A;  4H03 A;  2BOV B;  2GWL A;  2J3V A;  4DV8 A;  4XM7 A;  1GIR A;  2J3X A;  4H0X A;  1OG3 A;  1R4B A;  3NTS A;  4PKR A;  2C8D A;  2WN7 A;  5D1S A;  4PKV A;  1OG4 A;  2WN8 A;  2C8F E;  5GTT A;  5DZQ A;  1GZE A;  2WN6 A;  2C8E E;  4XM8 A;  4H0T A;  2C8B X;  5D1T A;  2WN4 A;  5H04 A;  4GY2 A;  5D1U A;  1GZF A;  1QS2 A;  2GWM A;  1GXY A;  1PWV A;  1G24 A;  1GY0 A;  1OG1 A;  1GXZ A;  5BWM B;  4GF1 A;  2C8H A;  4FK7 A;  1PWQ A;  1PWP A;  4FXQ A;  1PWU A;  2WN5 A;  4H0V A;  1J7N A;  1QS1 A;  3U0J A;  4XSG B;  1ZXV A;  2A9K B;  2C8G A; 
#chains in the Genus database with same CATH homology
 2C89 A;  4FML A;  2A78 B;  4PKS A;  1PWW A;  4ELN A;  2J3Z A;  5H03 A;  4XSH B;  4H0Y A;  4TR5 A;  1JKY A;  2C8A A;  1UZI A;  4WF6 A;  1OJQ A;  4PKU A;  4PKW A;  3BUZ A;  1GIQ A;  4PKQ A;  1R45 A;  4XM6 A;  2C8C A;  1OJZ A;  1YQY A;  4PKT A;  3BW8 A;  4H03 A;  2BOV B;  2GWL A;  2J3V A;  4DV8 A;  4XM7 A;  1GIR A;  2J3X A;  4H0X A;  1OG3 A;  1R4B A;  3NTS A;  4PKR A;  2C8D A;  2WN7 A;  5D1S A;  4PKV A;  1OG4 A;  2WN8 A;  2C8F E;  5GTT A;  5DZQ A;  1GZE A;  2WN6 A;  2C8E E;  4XM8 A;  4H0T A;  2C8B X;  5D1T A;  2WN4 A;  5H04 A;  4GY2 A;  5D1U A;  1GZF A;  1QS2 A;  2GWM A;  1GXY A;  1PWV A;  1G24 A;  1GY0 A;  1OG1 A;  1GXZ A;  5BWM B;  4GF1 A;  2C8H A;  4FK7 A;  1PWQ A;  1PWP A;  4FXQ A;  1PWU A;  2WN5 A;  4H0V A;  1J7N A;  1QS1 A;  3U0J A;  4XSG B;  1ZXV A;  2A9K B;  2C8G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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