2WN5A

Structural basis for substrate recognition in the enzymatic component of adp-ribosyltransferase toxin cdta from clostridium difficile
Total Genus 132
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
132
sequence length
397
structure length
394
Chain Sequence
KEWERKEAERIEQKLERSEKEALESYKKDSVEISKYSQTRNYFYDYQIEANSREKEYKELRNAISKNKIDKPMYVYYFESPEKFAFNKVIRTENQNEISLEKFNEFKETIQNKLFKQDGFKDISLYEPGKGDEKPTPLLMHLKLPRNTGMLPYTNNNVSTLIEQGYSIKIDKIVRIVIDGKHYIKAEASVVSSLDFKDDVSKGDSWGKANYNDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPVNNPNPELDSKITNIENALKREPIPTNLTVYRRSGPQEFGLTLTSPEYDFNKLENIDAFKSKWEGQALSYPNFISTSIGSVNMSAFAKRKIVLRITIPKGSPGAYLSAIPGYEYEVLLNHGSKFKINKIDSYKDGTITKLIVDATLIP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Substrate Recognition in the Enzymatic Component of Adp-Ribosyltransferase Toxin Cdta from Clostridium Difficile.
pubmed doi rcsb
molecule keywords ADP-RIBOSYLTRANSFERASE ENZYMATIC COMPONENT
molecule tags Transferase
source organism Clostridium difficile
total genus 132
structure length 394
sequence length 397
ec nomenclature
pdb deposition date 2009-07-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2wn5A02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2wn5A01
4FMLA 2GWLA 1R45A 4XM6A 2C8FE 2A9KB 3BW8A 2C8DA 1PWPA 1YQYA 4PKWA 4GY2A 5D1TA 4PKQA 1PWWA 1GY0A 2C8EE 5BWMB 4TR5A 1ZXVA 5DZQA 4H0TA 2WN8A 5D1UA 1OJQA 2C8HA 4PKTA 2C8AA 4FK7A 2WN4A 3BUZA 4PKUA 5H03A 4H0YA 4XM8A 3NTSA 4H0XA 1OJZA 4XSGB 1OG1A 1J7NA 5D1SA 2WN5A 1GIQA 2BOVB 2C8CA 2J3XA 1QS1A 4H03A 2J3VA 1R4BA 4FXQA 1GZEA 4ELNA 1OG4A 5H04A 4GF1A 1GXZA 2GWMA 2WN6A 2WN7A 1GXYA 4H0VA 1JKYA 1GZFA 1PWUA 1UZIA 4XSHB 4WF6A 2C8BX 4PKVA 1OG3A 4XM7A 2A78B 4DV8A 1QS2A 1PWVA 1G24A 3U0JA 4PKSA 4PKRA 1PWQA 5GTTA 2C89A 2C8GA 2J3ZA 1GIRA
chains in the Genus database with same CATH superfamily
4FMLA 2GWLA 1R45A 4XM6A 2C8FE 2A9KB 3BW8A 2C8DA 1PWPA 1YQYA 4PKWA 4GY2A 5D1TA 4PKQA 1PWWA 1GY0A 2C8EE 5BWMB 4TR5A 1ZXVA 5DZQA 4H0TA 2WN8A 5D1UA 1OJQA 2C8HA 4PKTA 2C8AA 4FK7A 2WN4A 3BUZA 4PKUA 5H03A 4H0YA 4XM8A 3NTSA 4H0XA 1OJZA 4XSGB 1OG1A 1J7NA 5D1SA 2WN5A 1GIQA 2BOVB 2C8CA 2J3XA 1QS1A 4H03A 2J3VA 1R4BA 4FXQA 1GZEA 4ELNA 1OG4A 5H04A 4GF1A 1GXZA 2GWMA 2WN6A 2WN7A 1GXYA 4H0VA 1JKYA 1GZFA 1PWUA 1UZIA 4XSHB 4WF6A 2C8BX 4PKVA 1OG3A 4XM7A 2A78B 4DV8A 1QS2A 1PWVA 1G24A 3U0JA 4PKSA 4PKRA 1PWQA 5GTTA 2C89A 2C8GA 2J3ZA 1GIRA
chains in the Genus database with same CATH topology
4FMLA 2GWLA 1R45A 4XM6A 2C8FE 2A9KB 3BW8A 2C8DA 1PWPA 1YQYA 4PKWA 4GY2A 5D1TA 4PKQA 1PWWA 1GY0A 2C8EE 5BWMB 4TR5A 1ZXVA 5DZQA 4H0TA 2WN8A 5D1UA 1OJQA 2C8HA 4PKTA 2C8AA 4FK7A 2WN4A 3BUZA 4PKUA 5H03A 4H0YA 4XM8A 3NTSA 4H0XA 1OJZA 4XSGB 1OG1A 1J7NA 5D1SA 2WN5A 1GIQA 2BOVB 2C8CA 2J3XA 1QS1A 4H03A 2J3VA 1R4BA 4FXQA 1GZEA 4ELNA 1OG4A 5H04A 4GF1A 1GXZA 2GWMA 2WN6A 2WN7A 1GXYA 4H0VA 1JKYA 1GZFA 1PWUA 1UZIA 4XSHB 4WF6A 2C8BX 4PKVA 1OG3A 4XM7A 2A78B 4DV8A 1QS2A 1PWVA 1G24A 3U0JA 4PKSA 4PKRA 1PWQA 5GTTA 2C89A 2C8GA 2J3ZA 1GIRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FML A;  2GWL A;  1R45 A;  4XM6 A;  2C8F E;  2A9K B;  3BW8 A;  2C8D A;  1PWP A;  1YQY A;  4PKW A;  4GY2 A;  5D1T A;  4PKQ A;  1PWW A;  1GY0 A;  2C8E E;  5BWM B;  4TR5 A;  1ZXV A;  5DZQ A;  4H0T A;  2WN8 A;  5D1U A;  1OJQ A;  2C8H A;  4PKT A;  2C8A A;  4FK7 A;  2WN4 A;  3BUZ A;  4PKU A;  5H03 A;  4H0Y A;  4XM8 A;  3NTS A;  4H0X A;  1OJZ A;  4XSG B;  1OG1 A;  1J7N A;  5D1S A;  2WN5 A;  1GIQ A;  2BOV B;  2C8C A;  2J3X A;  1QS1 A;  4H03 A;  2J3V A;  1R4B A;  4FXQ A;  1GZE A;  4ELN A;  1OG4 A;  5H04 A;  4GF1 A;  1GXZ A;  2GWM A;  2WN6 A;  2WN7 A;  1GXY A;  4H0V A;  1JKY A;  1GZF A;  1PWU A;  1UZI A;  4XSH B;  4WF6 A;  2C8B X;  4PKV A;  1OG3 A;  4XM7 A;  2A78 B;  4DV8 A;  1QS2 A;  1PWV A;  1G24 A;  3U0J A;  4PKS A;  4PKR A;  1PWQ A;  5GTT A;  2C89 A;  2C8G A;  2J3Z A;  1GIR A; 
#chains in the Genus database with same CATH topology
 4FML A;  2GWL A;  1R45 A;  4XM6 A;  2C8F E;  2A9K B;  3BW8 A;  2C8D A;  1PWP A;  1YQY A;  4PKW A;  4GY2 A;  5D1T A;  4PKQ A;  1PWW A;  1GY0 A;  2C8E E;  5BWM B;  4TR5 A;  1ZXV A;  5DZQ A;  4H0T A;  2WN8 A;  5D1U A;  1OJQ A;  2C8H A;  4PKT A;  2C8A A;  4FK7 A;  2WN4 A;  3BUZ A;  4PKU A;  5H03 A;  4H0Y A;  4XM8 A;  3NTS A;  4H0X A;  1OJZ A;  4XSG B;  1OG1 A;  1J7N A;  5D1S A;  2WN5 A;  1GIQ A;  2BOV B;  2C8C A;  2J3X A;  1QS1 A;  4H03 A;  2J3V A;  1R4B A;  4FXQ A;  1GZE A;  4ELN A;  1OG4 A;  5H04 A;  4GF1 A;  1GXZ A;  2GWM A;  2WN6 A;  2WN7 A;  1GXY A;  4H0V A;  1JKY A;  1GZF A;  1PWU A;  1UZI A;  4XSH B;  4WF6 A;  2C8B X;  4PKV A;  1OG3 A;  4XM7 A;  2A78 B;  4DV8 A;  1QS2 A;  1PWV A;  1G24 A;  3U0J A;  4PKS A;  4PKR A;  1PWQ A;  5GTT A;  2C89 A;  2C8G A;  2J3Z A;  1GIR A; 
#chains in the Genus database with same CATH homology
 4FML A;  2GWL A;  1R45 A;  4XM6 A;  2C8F E;  2A9K B;  3BW8 A;  2C8D A;  1PWP A;  1YQY A;  4PKW A;  4GY2 A;  5D1T A;  4PKQ A;  1PWW A;  1GY0 A;  2C8E E;  5BWM B;  4TR5 A;  1ZXV A;  5DZQ A;  4H0T A;  2WN8 A;  5D1U A;  1OJQ A;  2C8H A;  4PKT A;  2C8A A;  4FK7 A;  2WN4 A;  3BUZ A;  4PKU A;  5H03 A;  4H0Y A;  4XM8 A;  3NTS A;  4H0X A;  1OJZ A;  4XSG B;  1OG1 A;  1J7N A;  5D1S A;  2WN5 A;  1GIQ A;  2BOV B;  2C8C A;  2J3X A;  1QS1 A;  4H03 A;  2J3V A;  1R4B A;  4FXQ A;  1GZE A;  4ELN A;  1OG4 A;  5H04 A;  4GF1 A;  1GXZ A;  2GWM A;  2WN6 A;  2WN7 A;  1GXY A;  4H0V A;  1JKY A;  1GZF A;  1PWU A;  1UZI A;  4XSH B;  4WF6 A;  2C8B X;  4PKV A;  1OG3 A;  4XM7 A;  2A78 B;  4DV8 A;  1QS2 A;  1PWV A;  1G24 A;  3U0J A;  4PKS A;  4PKR A;  1PWQ A;  5GTT A;  2C89 A;  2C8G A;  2J3Z A;  1GIR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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