2A9KB

Crystal structure of the c3bot-nad-rala complex reveals a novel type of action of a bacterial exoenzyme
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
207
structure length
207
Chain Sequence
TYQEFTNIDQAKAWGNAQYKKYGLSKSEKEAIVSYTKSASEINGKLRQNKGVINGFPSNLIKQVELLDKSFNKMKTPENIMLFRGDDPAYLGTEFQNTLLNSNGTINKTAFEKAKAKFLNKDRLEYGYISTSLMNVSQFAGRPIITKFKVAKGSKAGYIDPISAFAGQLEMLLPRHSTYHIDDMRLSSDGKQIIITATMMGTAINPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Protein binding/transferase
molecule keywords Ras-related protein Ral-A
publication title Crystal structure of the C3bot-RalA complex reveals a novel type of action of a bacterial exoenzyme.
pubmed doi rcsb
source organism Homo sapiens
total genus 72
structure length 207
sequence length 207
ec nomenclature ec 2.4.2.-:
pdb deposition date 2005-07-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2a9kB00
2BOVB 1R4BA 2WN7A 3BUZA 1QS2A 5H04A 1G24A 4DV8A 1R45A 2C89A 1GY0A 1JKYA 2J3ZA 1PWWA 5D1SA 2WN5A 4PKTA 2A78B 1PWQA 4FMLA 3NTSA 2GWLA 5GTTA 1J7NA 2C8HA 1YQYA 4ELNA 2C8CA 1PWVA 4XSHB 4PKRA 1GXYA 5BWMB 1GIRA 4H03A 5DZQA 4PKQA 4XSGB 4PKUA 1PWPA 2WN6A 4GY2A 2J3VA 5D1UA 2A9KB 2J3XA 1ZXVA 3U0JA 1PWUA 2WN8A 4XM8A 2C8DA 1OG3A 4H0VA 4XM7A 2C8AA 2C8FE 1QS1A 2C8GA 1GIQA 1OG1A 1GXZA 5H03A 2GWMA 4PKSA 4TR5A 1GZEA 1UZIA 2C8EE 4PKWA 4FK7A 2WN4A 4FXQA 4PKVA 4H0XA 1OG4A 1OJZA 4XM6A 4GF1A 3BW8A 1OJQA 2C8BX 1GZFA 5D1TA 4WF6A 4H0TA 4H0YA
chains in the Genus database with same CATH superfamily
2BOVB 1R4BA 2WN7A 3BUZA 1QS2A 5H04A 1G24A 4DV8A 1R45A 2C89A 1GY0A 1JKYA 2J3ZA 1PWWA 5D1SA 2WN5A 4PKTA 2A78B 1PWQA 4FMLA 3NTSA 2GWLA 5GTTA 1J7NA 2C8HA 1YQYA 4ELNA 2C8CA 1PWVA 4XSHB 4PKRA 1GXYA 5BWMB 1GIRA 4H03A 5DZQA 4PKQA 4XSGB 4PKUA 1PWPA 2WN6A 4GY2A 2J3VA 5D1UA 2A9KB 2J3XA 1ZXVA 3U0JA 1PWUA 2WN8A 4XM8A 2C8DA 1OG3A 4H0VA 4XM7A 2C8AA 2C8FE 1QS1A 2C8GA 1GIQA 1OG1A 1GXZA 5H03A 2GWMA 4PKSA 4TR5A 1GZEA 1UZIA 2C8EE 4PKWA 4FK7A 2WN4A 4FXQA 4PKVA 4H0XA 1OG4A 1OJZA 4XM6A 4GF1A 3BW8A 1OJQA 2C8BX 1GZFA 5D1TA 4WF6A 4H0TA 4H0YA
chains in the Genus database with same CATH topology
2BOVB 1R4BA 2WN7A 3BUZA 1QS2A 5H04A 1G24A 4DV8A 1R45A 2C89A 1GY0A 1JKYA 2J3ZA 1PWWA 5D1SA 2WN5A 4PKTA 2A78B 1PWQA 4FMLA 3NTSA 2GWLA 5GTTA 1J7NA 2C8HA 1YQYA 4ELNA 2C8CA 1PWVA 4XSHB 4PKRA 1GXYA 5BWMB 1GIRA 4H03A 5DZQA 4PKQA 4XSGB 4PKUA 1PWPA 2WN6A 4GY2A 2J3VA 5D1UA 2A9KB 2J3XA 1ZXVA 3U0JA 1PWUA 2WN8A 4XM8A 2C8DA 1OG3A 4H0VA 4XM7A 2C8AA 2C8FE 1QS1A 2C8GA 1GIQA 1OG1A 1GXZA 5H03A 2GWMA 4PKSA 4TR5A 1GZEA 1UZIA 2C8EE 4PKWA 4FK7A 2WN4A 4FXQA 4PKVA 4H0XA 1OG4A 1OJZA 4XM6A 4GF1A 3BW8A 1OJQA 2C8BX 1GZFA 5D1TA 4WF6A 4H0TA 4H0YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BOV B;  1R4B A;  2WN7 A;  3BUZ A;  1QS2 A;  5H04 A;  1G24 A;  4DV8 A;  1R45 A;  2C89 A;  1GY0 A;  1JKY A;  2J3Z A;  1PWW A;  5D1S A;  2WN5 A;  4PKT A;  2A78 B;  1PWQ A;  4FML A;  3NTS A;  2GWL A;  5GTT A;  1J7N A;  2C8H A;  1YQY A;  4ELN A;  2C8C A;  1PWV A;  4XSH B;  4PKR A;  1GXY A;  5BWM B;  1GIR A;  4H03 A;  5DZQ A;  4PKQ A;  4XSG B;  4PKU A;  1PWP A;  2WN6 A;  4GY2 A;  2J3V A;  5D1U A;  2A9K B;  2J3X A;  1ZXV A;  3U0J A;  1PWU A;  2WN8 A;  4XM8 A;  2C8D A;  1OG3 A;  4H0V A;  4XM7 A;  2C8A A;  2C8F E;  1QS1 A;  2C8G A;  1GIQ A;  1OG1 A;  1GXZ A;  5H03 A;  2GWM A;  4PKS A;  4TR5 A;  1GZE A;  1UZI A;  2C8E E;  4PKW A;  4FK7 A;  2WN4 A;  4FXQ A;  4PKV A;  4H0X A;  1OG4 A;  1OJZ A;  4XM6 A;  4GF1 A;  3BW8 A;  1OJQ A;  2C8B X;  1GZF A;  5D1T A;  4WF6 A;  4H0T A;  4H0Y A; 
#chains in the Genus database with same CATH topology
 2BOV B;  1R4B A;  2WN7 A;  3BUZ A;  1QS2 A;  5H04 A;  1G24 A;  4DV8 A;  1R45 A;  2C89 A;  1GY0 A;  1JKY A;  2J3Z A;  1PWW A;  5D1S A;  2WN5 A;  4PKT A;  2A78 B;  1PWQ A;  4FML A;  3NTS A;  2GWL A;  5GTT A;  1J7N A;  2C8H A;  1YQY A;  4ELN A;  2C8C A;  1PWV A;  4XSH B;  4PKR A;  1GXY A;  5BWM B;  1GIR A;  4H03 A;  5DZQ A;  4PKQ A;  4XSG B;  4PKU A;  1PWP A;  2WN6 A;  4GY2 A;  2J3V A;  5D1U A;  2A9K B;  2J3X A;  1ZXV A;  3U0J A;  1PWU A;  2WN8 A;  4XM8 A;  2C8D A;  1OG3 A;  4H0V A;  4XM7 A;  2C8A A;  2C8F E;  1QS1 A;  2C8G A;  1GIQ A;  1OG1 A;  1GXZ A;  5H03 A;  2GWM A;  4PKS A;  4TR5 A;  1GZE A;  1UZI A;  2C8E E;  4PKW A;  4FK7 A;  2WN4 A;  4FXQ A;  4PKV A;  4H0X A;  1OG4 A;  1OJZ A;  4XM6 A;  4GF1 A;  3BW8 A;  1OJQ A;  2C8B X;  1GZF A;  5D1T A;  4WF6 A;  4H0T A;  4H0Y A; 
#chains in the Genus database with same CATH homology
 2BOV B;  1R4B A;  2WN7 A;  3BUZ A;  1QS2 A;  5H04 A;  1G24 A;  4DV8 A;  1R45 A;  2C89 A;  1GY0 A;  1JKY A;  2J3Z A;  1PWW A;  5D1S A;  2WN5 A;  4PKT A;  2A78 B;  1PWQ A;  4FML A;  3NTS A;  2GWL A;  5GTT A;  1J7N A;  2C8H A;  1YQY A;  4ELN A;  2C8C A;  1PWV A;  4XSH B;  4PKR A;  1GXY A;  5BWM B;  1GIR A;  4H03 A;  5DZQ A;  4PKQ A;  4XSG B;  4PKU A;  1PWP A;  2WN6 A;  4GY2 A;  2J3V A;  5D1U A;  2A9K B;  2J3X A;  1ZXV A;  3U0J A;  1PWU A;  2WN8 A;  4XM8 A;  2C8D A;  1OG3 A;  4H0V A;  4XM7 A;  2C8A A;  2C8F E;  1QS1 A;  2C8G A;  1GIQ A;  1OG1 A;  1GXZ A;  5H03 A;  2GWM A;  4PKS A;  4TR5 A;  1GZE A;  1UZI A;  2C8E E;  4PKW A;  4FK7 A;  2WN4 A;  4FXQ A;  4PKV A;  4H0X A;  1OG4 A;  1OJZ A;  4XM6 A;  4GF1 A;  3BW8 A;  1OJQ A;  2C8B X;  1GZF A;  5D1T A;  4WF6 A;  4H0T A;  4H0Y A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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