1GIRA

Crystal structure of the enzymatic componet of iota-toxin from clostridium perfringens with nadph
Total Genus 132
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
132
sequence length
411
structure length
411
Chain Sequence
IERPEDFLKDKENAIQWEKKEAERVEKNLDTLEKEALELYKKDSEQISNYSQTRQYFYDYQIESNPREKEYKNLRNAISKNKIDKPINVYYFESPEKFAFNKEIRTENQNEISLEKFNELKETIQDKLFKQDGFKDVSLYEPGNGDEKPTPLLIHLKLPKNTGMLPYINSNDVKTLIEQDYSIKIDKIVRIVIEGKQYIKAEASIVNSLDFKDDVSKGDLWGKENYSDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPLNNPNPELDSKVNNIENALKLTPIPSNLIVYRRSGPQEFGLTLTSPEYDFNKIENIDAFKEKWEGKVITYPNFISTSIGSVNMSAFAKRKIILRINIPKDSPGAYLSAIPGYAGEYEVLLNHGSKFKINKVDSYKDGTVTKLILDATLIN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin
molecule keywords IOTA TOXIN COMPONENT IA
publication title Crystal Structure and Site-directed Mutagenesis of Enzymatic Components from Clostridium perfringens Iota-toxin
pubmed doi rcsb
total genus 132
structure length 411
sequence length 411
ec nomenclature
pdb deposition date 2001-03-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 1girA02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 1girA01
1PWQA 3U0JA 2C8GA 1GZEA 1OJZA 1UZIA 1OG3A 5BWMB 1QS1A 4WF6A 2BOVB 4H0TA 1ZXVA 3BW8A 4GY2A 2C8HA 1GIQA 4PKRA 4XM7A 1PWUA 2WN4A 1QS2A 4ELNA 2J3VA 2C8AA 1OG1A 4PKTA 1R45A 1GY0A 2GWLA 5DZQA 2C8DA 1J7NA 3BUZA 2C89A 4PKSA 2WN6A 2J3XA 2C8BX 5H03A 1GZFA 4H0VA 4XM8A 4PKWA 2C8EE 2GWMA 1PWVA 2A78B 1G24A 1JKYA 4XM6A 2WN8A 4H03A 5D1SA 4PKVA 4XSHB 4DV8A 4FXQA 1YQYA 4PKQA 1GXZA 5GTTA 4GF1A 4FMLA 1R4BA 1PWWA 2WN5A 1OJQA 5D1UA 3NTSA 1GIRA 2C8FE 1PWPA 4PKUA 5H04A 1GXYA 4H0YA 4TR5A 2J3ZA 2A9KB 4FK7A 4H0XA 1OG4A 2C8CA 4XSGB 5D1TA 2WN7A
chains in the Genus database with same CATH superfamily
1PWQA 3U0JA 2C8GA 1GZEA 1OJZA 1UZIA 1OG3A 5BWMB 1QS1A 4WF6A 2BOVB 4H0TA 1ZXVA 3BW8A 4GY2A 2C8HA 1GIQA 4PKRA 4XM7A 1PWUA 2WN4A 1QS2A 4ELNA 2J3VA 2C8AA 1OG1A 4PKTA 1R45A 1GY0A 2GWLA 5DZQA 2C8DA 1J7NA 3BUZA 2C89A 4PKSA 2WN6A 2J3XA 2C8BX 5H03A 1GZFA 4H0VA 4XM8A 4PKWA 2C8EE 2GWMA 1PWVA 2A78B 1G24A 1JKYA 4XM6A 2WN8A 4H03A 5D1SA 4PKVA 4XSHB 4DV8A 4FXQA 1YQYA 4PKQA 1GXZA 5GTTA 4GF1A 4FMLA 1R4BA 1PWWA 2WN5A 1OJQA 5D1UA 3NTSA 1GIRA 2C8FE 1PWPA 4PKUA 5H04A 1GXYA 4H0YA 4TR5A 2J3ZA 2A9KB 4FK7A 4H0XA 1OG4A 2C8CA 4XSGB 5D1TA 2WN7A
chains in the Genus database with same CATH topology
1PWQA 3U0JA 2C8GA 1GZEA 1OJZA 1UZIA 1OG3A 5BWMB 1QS1A 4WF6A 2BOVB 4H0TA 1ZXVA 3BW8A 4GY2A 2C8HA 1GIQA 4PKRA 4XM7A 1PWUA 2WN4A 1QS2A 4ELNA 2J3VA 2C8AA 1OG1A 4PKTA 1R45A 1GY0A 2GWLA 5DZQA 2C8DA 1J7NA 3BUZA 2C89A 4PKSA 2WN6A 2J3XA 2C8BX 5H03A 1GZFA 4H0VA 4XM8A 4PKWA 2C8EE 2GWMA 1PWVA 2A78B 1G24A 1JKYA 4XM6A 2WN8A 4H03A 5D1SA 4PKVA 4XSHB 4DV8A 4FXQA 1YQYA 4PKQA 1GXZA 5GTTA 4GF1A 4FMLA 1R4BA 1PWWA 2WN5A 1OJQA 5D1UA 3NTSA 1GIRA 2C8FE 1PWPA 4PKUA 5H04A 1GXYA 4H0YA 4TR5A 2J3ZA 2A9KB 4FK7A 4H0XA 1OG4A 2C8CA 4XSGB 5D1TA 2WN7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PWQ A;  3U0J A;  2C8G A;  1GZE A;  1OJZ A;  1UZI A;  1OG3 A;  5BWM B;  1QS1 A;  4WF6 A;  2BOV B;  4H0T A;  1ZXV A;  3BW8 A;  4GY2 A;  2C8H A;  1GIQ A;  4PKR A;  4XM7 A;  1PWU A;  2WN4 A;  1QS2 A;  4ELN A;  2J3V A;  2C8A A;  1OG1 A;  4PKT A;  1R45 A;  1GY0 A;  2GWL A;  5DZQ A;  2C8D A;  1J7N A;  3BUZ A;  2C89 A;  4PKS A;  2WN6 A;  2J3X A;  2C8B X;  5H03 A;  1GZF A;  4H0V A;  4XM8 A;  4PKW A;  2C8E E;  2GWM A;  1PWV A;  2A78 B;  1G24 A;  1JKY A;  4XM6 A;  2WN8 A;  4H03 A;  5D1S A;  4PKV A;  4XSH B;  4DV8 A;  4FXQ A;  1YQY A;  4PKQ A;  1GXZ A;  5GTT A;  4GF1 A;  4FML A;  1R4B A;  1PWW A;  2WN5 A;  1OJQ A;  5D1U A;  3NTS A;  1GIR A;  2C8F E;  1PWP A;  4PKU A;  5H04 A;  1GXY A;  4H0Y A;  4TR5 A;  2J3Z A;  2A9K B;  4FK7 A;  4H0X A;  1OG4 A;  2C8C A;  4XSG B;  5D1T A;  2WN7 A; 
#chains in the Genus database with same CATH topology
 1PWQ A;  3U0J A;  2C8G A;  1GZE A;  1OJZ A;  1UZI A;  1OG3 A;  5BWM B;  1QS1 A;  4WF6 A;  2BOV B;  4H0T A;  1ZXV A;  3BW8 A;  4GY2 A;  2C8H A;  1GIQ A;  4PKR A;  4XM7 A;  1PWU A;  2WN4 A;  1QS2 A;  4ELN A;  2J3V A;  2C8A A;  1OG1 A;  4PKT A;  1R45 A;  1GY0 A;  2GWL A;  5DZQ A;  2C8D A;  1J7N A;  3BUZ A;  2C89 A;  4PKS A;  2WN6 A;  2J3X A;  2C8B X;  5H03 A;  1GZF A;  4H0V A;  4XM8 A;  4PKW A;  2C8E E;  2GWM A;  1PWV A;  2A78 B;  1G24 A;  1JKY A;  4XM6 A;  2WN8 A;  4H03 A;  5D1S A;  4PKV A;  4XSH B;  4DV8 A;  4FXQ A;  1YQY A;  4PKQ A;  1GXZ A;  5GTT A;  4GF1 A;  4FML A;  1R4B A;  1PWW A;  2WN5 A;  1OJQ A;  5D1U A;  3NTS A;  1GIR A;  2C8F E;  1PWP A;  4PKU A;  5H04 A;  1GXY A;  4H0Y A;  4TR5 A;  2J3Z A;  2A9K B;  4FK7 A;  4H0X A;  1OG4 A;  2C8C A;  4XSG B;  5D1T A;  2WN7 A; 
#chains in the Genus database with same CATH homology
 1PWQ A;  3U0J A;  2C8G A;  1GZE A;  1OJZ A;  1UZI A;  1OG3 A;  5BWM B;  1QS1 A;  4WF6 A;  2BOV B;  4H0T A;  1ZXV A;  3BW8 A;  4GY2 A;  2C8H A;  1GIQ A;  4PKR A;  4XM7 A;  1PWU A;  2WN4 A;  1QS2 A;  4ELN A;  2J3V A;  2C8A A;  1OG1 A;  4PKT A;  1R45 A;  1GY0 A;  2GWL A;  5DZQ A;  2C8D A;  1J7N A;  3BUZ A;  2C89 A;  4PKS A;  2WN6 A;  2J3X A;  2C8B X;  5H03 A;  1GZF A;  4H0V A;  4XM8 A;  4PKW A;  2C8E E;  2GWM A;  1PWV A;  2A78 B;  1G24 A;  1JKY A;  4XM6 A;  2WN8 A;  4H03 A;  5D1S A;  4PKV A;  4XSH B;  4DV8 A;  4FXQ A;  1YQY A;  4PKQ A;  1GXZ A;  5GTT A;  4GF1 A;  4FML A;  1R4B A;  1PWW A;  2WN5 A;  1OJQ A;  5D1U A;  3NTS A;  1GIR A;  2C8F E;  1PWP A;  4PKU A;  5H04 A;  1GXY A;  4H0Y A;  4TR5 A;  2J3Z A;  2A9K B;  4FK7 A;  4H0X A;  1OG4 A;  2C8C A;  4XSG B;  5D1T A;  2WN7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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