1GIRA

Crystal structure of the enzymatic componet of iota-toxin from clostridium perfringens with nadph
Total Genus 132
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
132
sequence length
411
structure length
411
Chain Sequence
IERPEDFLKDKENAIQWEKKEAERVEKNLDTLEKEALELYKKDSEQISNYSQTRQYFYDYQIESNPREKEYKNLRNAISKNKIDKPINVYYFESPEKFAFNKEIRTENQNEISLEKFNELKETIQDKLFKQDGFKDVSLYEPGNGDEKPTPLLIHLKLPKNTGMLPYINSNDVKTLIEQDYSIKIDKIVRIVIEGKQYIKAEASIVNSLDFKDDVSKGDLWGKENYSDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPLNNPNPELDSKVNNIENALKLTPIPSNLIVYRRSGPQEFGLTLTSPEYDFNKIENIDAFKEKWEGKVITYPNFISTSIGSVNMSAFAKRKIILRINIPKDSPGAYLSAIPGYAGEYEVLLNHGSKFKINKVDSYKDGTVTKLILDATLIN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin
molecule keywords IOTA TOXIN COMPONENT IA
publication title Crystal Structure and Site-directed Mutagenesis of Enzymatic Components from Clostridium perfringens Iota-toxin
pubmed doi rcsb
total genus 132
structure length 411
sequence length 411
ec nomenclature
pdb deposition date 2001-03-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 1girA02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 1girA01
1GIQA 2C89A 2C8BX 4XM7A 3BUZA 4FXQA 4PKQA 2C8CA 3NTSA 4H0VA 4H0TA 4PKUA 1GZEA 1PWQA 1OG4A 2J3VA 1ZXVA 1OG3A 1GZFA 4XM8A 2GWMA 1PWVA 4PKSA 5H04A 1YQYA 4H0XA 4H0YA 4ELNA 4TR5A 2C8EE 1UZIA 1OG1A 4FK7A 4WF6A 2WN8A 1GXZA 4XSHB 1JKYA 5GTTA 2C8DA 3BW8A 2GWLA 1GXYA 2C8AA 1R45A 4PKTA 1GY0A 4GY2A 5BWMB 4H03A 2A9KB 2C8FE 4DV8A 5H03A 5D1TA 4XSGB 2WN6A 1G24A 4PKVA 5D1SA 5D1UA 2WN4A 5DZQA 4FMLA 1OJZA 2BOVB 2A78B 1OJQA 4PKRA 2J3ZA 2WN7A 1PWWA 1R4BA 2C8HA 2C8GA 3U0JA 2J3XA 1J7NA 1GIRA 4XM6A 4GF1A 1QS1A 4PKWA 1PWUA 1PWPA 2WN5A 1QS2A
chains in the Genus database with same CATH superfamily
1GIQA 2C89A 2C8BX 4XM7A 3BUZA 4FXQA 4PKQA 2C8CA 3NTSA 4H0VA 4H0TA 4PKUA 1GZEA 1PWQA 1OG4A 2J3VA 1ZXVA 1OG3A 1GZFA 4XM8A 2GWMA 1PWVA 4PKSA 5H04A 1YQYA 4H0XA 4H0YA 4ELNA 4TR5A 2C8EE 1UZIA 1OG1A 4FK7A 4WF6A 2WN8A 1GXZA 4XSHB 1JKYA 5GTTA 2C8DA 3BW8A 2GWLA 1GXYA 2C8AA 1R45A 4PKTA 1GY0A 4GY2A 5BWMB 4H03A 2A9KB 2C8FE 4DV8A 5H03A 5D1TA 4XSGB 2WN6A 1G24A 4PKVA 5D1SA 5D1UA 2WN4A 5DZQA 4FMLA 1OJZA 2BOVB 2A78B 1OJQA 4PKRA 2J3ZA 2WN7A 1PWWA 1R4BA 2C8HA 2C8GA 3U0JA 2J3XA 1J7NA 1GIRA 4XM6A 4GF1A 1QS1A 4PKWA 1PWUA 1PWPA 2WN5A 1QS2A
chains in the Genus database with same CATH topology
1GIQA 2C89A 2C8BX 4XM7A 3BUZA 4FXQA 4PKQA 2C8CA 3NTSA 4H0VA 4H0TA 4PKUA 1GZEA 1PWQA 1OG4A 2J3VA 1ZXVA 1OG3A 1GZFA 4XM8A 2GWMA 1PWVA 4PKSA 5H04A 1YQYA 4H0XA 4H0YA 4ELNA 4TR5A 2C8EE 1UZIA 1OG1A 4FK7A 4WF6A 2WN8A 1GXZA 4XSHB 1JKYA 5GTTA 2C8DA 3BW8A 2GWLA 1GXYA 2C8AA 1R45A 4PKTA 1GY0A 4GY2A 5BWMB 4H03A 2A9KB 2C8FE 4DV8A 5H03A 5D1TA 4XSGB 2WN6A 1G24A 4PKVA 5D1SA 5D1UA 2WN4A 5DZQA 4FMLA 1OJZA 2BOVB 2A78B 1OJQA 4PKRA 2J3ZA 2WN7A 1PWWA 1R4BA 2C8HA 2C8GA 3U0JA 2J3XA 1J7NA 1GIRA 4XM6A 4GF1A 1QS1A 4PKWA 1PWUA 1PWPA 2WN5A 1QS2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GIQ A;  2C89 A;  2C8B X;  4XM7 A;  3BUZ A;  4FXQ A;  4PKQ A;  2C8C A;  3NTS A;  4H0V A;  4H0T A;  4PKU A;  1GZE A;  1PWQ A;  1OG4 A;  2J3V A;  1ZXV A;  1OG3 A;  1GZF A;  4XM8 A;  2GWM A;  1PWV A;  4PKS A;  5H04 A;  1YQY A;  4H0X A;  4H0Y A;  4ELN A;  4TR5 A;  2C8E E;  1UZI A;  1OG1 A;  4FK7 A;  4WF6 A;  2WN8 A;  1GXZ A;  4XSH B;  1JKY A;  5GTT A;  2C8D A;  3BW8 A;  2GWL A;  1GXY A;  2C8A A;  1R45 A;  4PKT A;  1GY0 A;  4GY2 A;  5BWM B;  4H03 A;  2A9K B;  2C8F E;  4DV8 A;  5H03 A;  5D1T A;  4XSG B;  2WN6 A;  1G24 A;  4PKV A;  5D1S A;  5D1U A;  2WN4 A;  5DZQ A;  4FML A;  1OJZ A;  2BOV B;  2A78 B;  1OJQ A;  4PKR A;  2J3Z A;  2WN7 A;  1PWW A;  1R4B A;  2C8H A;  2C8G A;  3U0J A;  2J3X A;  1J7N A;  1GIR A;  4XM6 A;  4GF1 A;  1QS1 A;  4PKW A;  1PWU A;  1PWP A;  2WN5 A;  1QS2 A; 
#chains in the Genus database with same CATH topology
 1GIQ A;  2C89 A;  2C8B X;  4XM7 A;  3BUZ A;  4FXQ A;  4PKQ A;  2C8C A;  3NTS A;  4H0V A;  4H0T A;  4PKU A;  1GZE A;  1PWQ A;  1OG4 A;  2J3V A;  1ZXV A;  1OG3 A;  1GZF A;  4XM8 A;  2GWM A;  1PWV A;  4PKS A;  5H04 A;  1YQY A;  4H0X A;  4H0Y A;  4ELN A;  4TR5 A;  2C8E E;  1UZI A;  1OG1 A;  4FK7 A;  4WF6 A;  2WN8 A;  1GXZ A;  4XSH B;  1JKY A;  5GTT A;  2C8D A;  3BW8 A;  2GWL A;  1GXY A;  2C8A A;  1R45 A;  4PKT A;  1GY0 A;  4GY2 A;  5BWM B;  4H03 A;  2A9K B;  2C8F E;  4DV8 A;  5H03 A;  5D1T A;  4XSG B;  2WN6 A;  1G24 A;  4PKV A;  5D1S A;  5D1U A;  2WN4 A;  5DZQ A;  4FML A;  1OJZ A;  2BOV B;  2A78 B;  1OJQ A;  4PKR A;  2J3Z A;  2WN7 A;  1PWW A;  1R4B A;  2C8H A;  2C8G A;  3U0J A;  2J3X A;  1J7N A;  1GIR A;  4XM6 A;  4GF1 A;  1QS1 A;  4PKW A;  1PWU A;  1PWP A;  2WN5 A;  1QS2 A; 
#chains in the Genus database with same CATH homology
 1GIQ A;  2C89 A;  2C8B X;  4XM7 A;  3BUZ A;  4FXQ A;  4PKQ A;  2C8C A;  3NTS A;  4H0V A;  4H0T A;  4PKU A;  1GZE A;  1PWQ A;  1OG4 A;  2J3V A;  1ZXV A;  1OG3 A;  1GZF A;  4XM8 A;  2GWM A;  1PWV A;  4PKS A;  5H04 A;  1YQY A;  4H0X A;  4H0Y A;  4ELN A;  4TR5 A;  2C8E E;  1UZI A;  1OG1 A;  4FK7 A;  4WF6 A;  2WN8 A;  1GXZ A;  4XSH B;  1JKY A;  5GTT A;  2C8D A;  3BW8 A;  2GWL A;  1GXY A;  2C8A A;  1R45 A;  4PKT A;  1GY0 A;  4GY2 A;  5BWM B;  4H03 A;  2A9K B;  2C8F E;  4DV8 A;  5H03 A;  5D1T A;  4XSG B;  2WN6 A;  1G24 A;  4PKV A;  5D1S A;  5D1U A;  2WN4 A;  5DZQ A;  4FML A;  1OJZ A;  2BOV B;  2A78 B;  1OJQ A;  4PKR A;  2J3Z A;  2WN7 A;  1PWW A;  1R4B A;  2C8H A;  2C8G A;  3U0J A;  2J3X A;  1J7N A;  1GIR A;  4XM6 A;  4GF1 A;  1QS1 A;  4PKW A;  1PWU A;  1PWP A;  2WN5 A;  1QS2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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