1GIRA

Crystal structure of the enzymatic componet of iota-toxin from clostridium perfringens with nadph
Total Genus 132
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
132
sequence length
411
structure length
411
Chain Sequence
IERPEDFLKDKENAIQWEKKEAERVEKNLDTLEKEALELYKKDSEQISNYSQTRQYFYDYQIESNPREKEYKNLRNAISKNKIDKPINVYYFESPEKFAFNKEIRTENQNEISLEKFNELKETIQDKLFKQDGFKDVSLYEPGNGDEKPTPLLIHLKLPKNTGMLPYINSNDVKTLIEQDYSIKIDKIVRIVIEGKQYIKAEASIVNSLDFKDDVSKGDLWGKENYSDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPLNNPNPELDSKVNNIENALKLTPIPSNLIVYRRSGPQEFGLTLTSPEYDFNKIENIDAFKEKWEGKVITYPNFISTSIGSVNMSAFAKRKIILRINIPKDSPGAYLSAIPGYAGEYEVLLNHGSKFKINKVDSYKDGTVTKLILDATLIN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords IOTA TOXIN COMPONENT IA
publication title Crystal Structure and Site-directed Mutagenesis of Enzymatic Components from Clostridium perfringens Iota-toxin
pubmed doi rcsb
molecule tags Toxin
total genus 132
structure length 411
sequence length 411
ec nomenclature
pdb deposition date 2001-03-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 1girA02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 1girA01
1J7NA 2WN7A 1GXYA 2WN8A 2A9KB 5D1UA 3U0JA 4PKVA 4PKUA 1QS2A 1GY0A 4WF6A 4PKTA 4GY2A 1OG1A 4FMLA 4H0TA 4FK7A 4H0VA 1R4BA 1JKYA 5H04A 4PKRA 2C8EE 2GWMA 5DZQA 1GIRA 3BW8A 5D1SA 4XSHB 4H0XA 4PKSA 1UZIA 2WN4A 2A78B 1GXZA 2BOVB 2WN5A 2C8HA 2C8GA 4ELNA 1OG4A 3BUZA 4XM7A 1PWVA 4PKQA 1R45A 1ZXVA 1QS1A 2C89A 4XM8A 1G24A 2WN6A 3NTSA 2C8CA 2J3VA 1PWWA 4H0YA 4H03A 2C8AA 4GF1A 5GTTA 4FXQA 1PWPA 1PWUA 1OJZA 1YQYA 4XSGB 2J3XA 2C8FE 4PKWA 1OG3A 5BWMB 1GZFA 1GZEA 4XM6A 1OJQA 4DV8A 1PWQA 4TR5A 5H03A 1GIQA 2J3ZA 2C8BX 2GWLA 5D1TA 2C8DA
chains in the Genus database with same CATH superfamily
1J7NA 2WN7A 1GXYA 2WN8A 2A9KB 5D1UA 3U0JA 4PKVA 4PKUA 1QS2A 1GY0A 4WF6A 4PKTA 4GY2A 1OG1A 4FMLA 4H0TA 4FK7A 4H0VA 1R4BA 1JKYA 5H04A 4PKRA 2C8EE 2GWMA 5DZQA 1GIRA 3BW8A 5D1SA 4XSHB 4H0XA 4PKSA 1UZIA 2WN4A 2A78B 1GXZA 2BOVB 2WN5A 2C8HA 2C8GA 4ELNA 1OG4A 3BUZA 4XM7A 1PWVA 4PKQA 1R45A 1ZXVA 1QS1A 2C89A 4XM8A 1G24A 2WN6A 3NTSA 2C8CA 2J3VA 1PWWA 4H0YA 4H03A 2C8AA 4GF1A 5GTTA 4FXQA 1PWPA 1PWUA 1OJZA 1YQYA 4XSGB 2J3XA 2C8FE 4PKWA 1OG3A 5BWMB 1GZFA 1GZEA 4XM6A 1OJQA 4DV8A 1PWQA 4TR5A 5H03A 1GIQA 2J3ZA 2C8BX 2GWLA 5D1TA 2C8DA
chains in the Genus database with same CATH topology
1J7NA 2WN7A 1GXYA 2WN8A 2A9KB 5D1UA 3U0JA 4PKVA 4PKUA 1QS2A 1GY0A 4WF6A 4PKTA 4GY2A 1OG1A 4FMLA 4H0TA 4FK7A 4H0VA 1R4BA 1JKYA 5H04A 4PKRA 2C8EE 2GWMA 5DZQA 1GIRA 3BW8A 5D1SA 4XSHB 4H0XA 4PKSA 1UZIA 2WN4A 2A78B 1GXZA 2BOVB 2WN5A 2C8HA 2C8GA 4ELNA 1OG4A 3BUZA 4XM7A 1PWVA 4PKQA 1R45A 1ZXVA 1QS1A 2C89A 4XM8A 1G24A 2WN6A 3NTSA 2C8CA 2J3VA 1PWWA 4H0YA 4H03A 2C8AA 4GF1A 5GTTA 4FXQA 1PWPA 1PWUA 1OJZA 1YQYA 4XSGB 2J3XA 2C8FE 4PKWA 1OG3A 5BWMB 1GZFA 1GZEA 4XM6A 1OJQA 4DV8A 1PWQA 4TR5A 5H03A 1GIQA 2J3ZA 2C8BX 2GWLA 5D1TA 2C8DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1J7N A;  2WN7 A;  1GXY A;  2WN8 A;  2A9K B;  5D1U A;  3U0J A;  4PKV A;  4PKU A;  1QS2 A;  1GY0 A;  4WF6 A;  4PKT A;  4GY2 A;  1OG1 A;  4FML A;  4H0T A;  4FK7 A;  4H0V A;  1R4B A;  1JKY A;  5H04 A;  4PKR A;  2C8E E;  2GWM A;  5DZQ A;  1GIR A;  3BW8 A;  5D1S A;  4XSH B;  4H0X A;  4PKS A;  1UZI A;  2WN4 A;  2A78 B;  1GXZ A;  2BOV B;  2WN5 A;  2C8H A;  2C8G A;  4ELN A;  1OG4 A;  3BUZ A;  4XM7 A;  1PWV A;  4PKQ A;  1R45 A;  1ZXV A;  1QS1 A;  2C89 A;  4XM8 A;  1G24 A;  2WN6 A;  3NTS A;  2C8C A;  2J3V A;  1PWW A;  4H0Y A;  4H03 A;  2C8A A;  4GF1 A;  5GTT A;  4FXQ A;  1PWP A;  1PWU A;  1OJZ A;  1YQY A;  4XSG B;  2J3X A;  2C8F E;  4PKW A;  1OG3 A;  5BWM B;  1GZF A;  1GZE A;  4XM6 A;  1OJQ A;  4DV8 A;  1PWQ A;  4TR5 A;  5H03 A;  1GIQ A;  2J3Z A;  2C8B X;  2GWL A;  5D1T A;  2C8D A; 
#chains in the Genus database with same CATH topology
 1J7N A;  2WN7 A;  1GXY A;  2WN8 A;  2A9K B;  5D1U A;  3U0J A;  4PKV A;  4PKU A;  1QS2 A;  1GY0 A;  4WF6 A;  4PKT A;  4GY2 A;  1OG1 A;  4FML A;  4H0T A;  4FK7 A;  4H0V A;  1R4B A;  1JKY A;  5H04 A;  4PKR A;  2C8E E;  2GWM A;  5DZQ A;  1GIR A;  3BW8 A;  5D1S A;  4XSH B;  4H0X A;  4PKS A;  1UZI A;  2WN4 A;  2A78 B;  1GXZ A;  2BOV B;  2WN5 A;  2C8H A;  2C8G A;  4ELN A;  1OG4 A;  3BUZ A;  4XM7 A;  1PWV A;  4PKQ A;  1R45 A;  1ZXV A;  1QS1 A;  2C89 A;  4XM8 A;  1G24 A;  2WN6 A;  3NTS A;  2C8C A;  2J3V A;  1PWW A;  4H0Y A;  4H03 A;  2C8A A;  4GF1 A;  5GTT A;  4FXQ A;  1PWP A;  1PWU A;  1OJZ A;  1YQY A;  4XSG B;  2J3X A;  2C8F E;  4PKW A;  1OG3 A;  5BWM B;  1GZF A;  1GZE A;  4XM6 A;  1OJQ A;  4DV8 A;  1PWQ A;  4TR5 A;  5H03 A;  1GIQ A;  2J3Z A;  2C8B X;  2GWL A;  5D1T A;  2C8D A; 
#chains in the Genus database with same CATH homology
 1J7N A;  2WN7 A;  1GXY A;  2WN8 A;  2A9K B;  5D1U A;  3U0J A;  4PKV A;  4PKU A;  1QS2 A;  1GY0 A;  4WF6 A;  4PKT A;  4GY2 A;  1OG1 A;  4FML A;  4H0T A;  4FK7 A;  4H0V A;  1R4B A;  1JKY A;  5H04 A;  4PKR A;  2C8E E;  2GWM A;  5DZQ A;  1GIR A;  3BW8 A;  5D1S A;  4XSH B;  4H0X A;  4PKS A;  1UZI A;  2WN4 A;  2A78 B;  1GXZ A;  2BOV B;  2WN5 A;  2C8H A;  2C8G A;  4ELN A;  1OG4 A;  3BUZ A;  4XM7 A;  1PWV A;  4PKQ A;  1R45 A;  1ZXV A;  1QS1 A;  2C89 A;  4XM8 A;  1G24 A;  2WN6 A;  3NTS A;  2C8C A;  2J3V A;  1PWW A;  4H0Y A;  4H03 A;  2C8A A;  4GF1 A;  5GTT A;  4FXQ A;  1PWP A;  1PWU A;  1OJZ A;  1YQY A;  4XSG B;  2J3X A;  2C8F E;  4PKW A;  1OG3 A;  5BWM B;  1GZF A;  1GZE A;  4XM6 A;  1OJQ A;  4DV8 A;  1PWQ A;  4TR5 A;  5H03 A;  1GIQ A;  2J3Z A;  2C8B X;  2GWL A;  5D1T A;  2C8D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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