4H03A

Crystal structure of nad+-ia-actin complex
Total Genus 147
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
147
sequence length
414
structure length
414
Chain Sequence
MAFIERPEDFLKDKENAIQWEKKEAERVEKNLDTLEKEALELYKKDSEQISNYSQTRQYFYDYQIESNPREKEYKNLRNAISKNKIDKPINVYYFESPEKFAFNKEIRTENQNEISLEKFNELKETIQDKLFKQDGFKDVSLYEPGNGDEKPTPLLIHLKLPKNTGMLPYINSNDVKTLIEQDYSIKIDKIVRIVIEGKQYIKAEASIVNSLDFKDDVSKGDLWGKENYSDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPLNNPNPELDSKVNNIENALKLTPIPSNLIVYRRSGPQEFGLTLTSPEYDFNKIENIDAFKEKWEGKVITYPNFISTSIGSVNMSAFAKRKIILRINIPKDSPGAYLSAIPGYAGEYEVLLNHGSKFKINKVDSYKDGTVTKLILDATLIN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Iota toxin component Ia
publication title Arginine ADP-ribosylation mechanism based on structural snapshots of iota-toxin and actin complex
pubmed doi rcsb
source organism Clostridium perfringens
molecule tags Toxin/structural protein
total genus 147
structure length 414
sequence length 414
ec nomenclature ec 2.4.2.31: NAD(+)--protein-arginine ADP-ribosyltransferase.
pdb deposition date 2012-09-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4h03A02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4h03A01
4H0XA 1JKYA 4PKVA 1OJZA 2J3XA 2WN7A 1GY0A 2C8BX 1PWQA 4H0VA 4GY2A 2A78B 2BOVB 5BWMB 2WN4A 2J3ZA 1YQYA 2C8HA 5D1UA 2GWMA 1PWWA 4TR5A 1GIRA 4DV8A 4FK7A 2C8AA 1PWPA 2C8DA 2C8GA 4XM6A 3BUZA 2WN8A 3BW8A 4PKTA 5D1TA 5DZQA 3NTSA 2C8EE 1R45A 3U0JA 4XSHB 1R4BA 2J3VA 1OJQA 1GXZA 2WN6A 1UZIA 1GZEA 1GXYA 1QS1A 1GZFA 4FXQA 1GIQA 4FMLA 1PWVA 5GTTA 4H0TA 1OG4A 4H03A 1J7NA 5H04A 4PKUA 4XM7A 4XSGB 4ELNA 2C89A 2GWLA 1G24A 2A9KB 1OG1A 2WN5A 1OG3A 4PKQA 4GF1A 5D1SA 1QS2A 4WF6A 4H0YA 2C8CA 4PKSA 4PKRA 4XM8A 1PWUA 1ZXVA 2C8FE 4PKWA 5H03A
chains in the Genus database with same CATH superfamily
4H0XA 1JKYA 4PKVA 1OJZA 2J3XA 2WN7A 1GY0A 2C8BX 1PWQA 4H0VA 4GY2A 2A78B 2BOVB 5BWMB 2WN4A 2J3ZA 1YQYA 2C8HA 5D1UA 2GWMA 1PWWA 4TR5A 1GIRA 4DV8A 4FK7A 2C8AA 1PWPA 2C8DA 2C8GA 4XM6A 3BUZA 2WN8A 3BW8A 4PKTA 5D1TA 5DZQA 3NTSA 2C8EE 1R45A 3U0JA 4XSHB 1R4BA 2J3VA 1OJQA 1GXZA 2WN6A 1UZIA 1GZEA 1GXYA 1QS1A 1GZFA 4FXQA 1GIQA 4FMLA 1PWVA 5GTTA 4H0TA 1OG4A 4H03A 1J7NA 5H04A 4PKUA 4XM7A 4XSGB 4ELNA 2C89A 2GWLA 1G24A 2A9KB 1OG1A 2WN5A 1OG3A 4PKQA 4GF1A 5D1SA 1QS2A 4WF6A 4H0YA 2C8CA 4PKSA 4PKRA 4XM8A 1PWUA 1ZXVA 2C8FE 4PKWA 5H03A
chains in the Genus database with same CATH topology
4H0XA 1JKYA 4PKVA 1OJZA 2J3XA 2WN7A 1GY0A 2C8BX 1PWQA 4H0VA 4GY2A 2A78B 2BOVB 5BWMB 2WN4A 2J3ZA 1YQYA 2C8HA 5D1UA 2GWMA 1PWWA 4TR5A 1GIRA 4DV8A 4FK7A 2C8AA 1PWPA 2C8DA 2C8GA 4XM6A 3BUZA 2WN8A 3BW8A 4PKTA 5D1TA 5DZQA 3NTSA 2C8EE 1R45A 3U0JA 4XSHB 1R4BA 2J3VA 1OJQA 1GXZA 2WN6A 1UZIA 1GZEA 1GXYA 1QS1A 1GZFA 4FXQA 1GIQA 4FMLA 1PWVA 5GTTA 4H0TA 1OG4A 4H03A 1J7NA 5H04A 4PKUA 4XM7A 4XSGB 4ELNA 2C89A 2GWLA 1G24A 2A9KB 1OG1A 2WN5A 1OG3A 4PKQA 4GF1A 5D1SA 1QS2A 4WF6A 4H0YA 2C8CA 4PKSA 4PKRA 4XM8A 1PWUA 1ZXVA 2C8FE 4PKWA 5H03A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4H0X A;  1JKY A;  4PKV A;  1OJZ A;  2J3X A;  2WN7 A;  1GY0 A;  2C8B X;  1PWQ A;  4H0V A;  4GY2 A;  2A78 B;  2BOV B;  5BWM B;  2WN4 A;  2J3Z A;  1YQY A;  2C8H A;  5D1U A;  2GWM A;  1PWW A;  4TR5 A;  1GIR A;  4DV8 A;  4FK7 A;  2C8A A;  1PWP A;  2C8D A;  2C8G A;  4XM6 A;  3BUZ A;  2WN8 A;  3BW8 A;  4PKT A;  5D1T A;  5DZQ A;  3NTS A;  2C8E E;  1R45 A;  3U0J A;  4XSH B;  1R4B A;  2J3V A;  1OJQ A;  1GXZ A;  2WN6 A;  1UZI A;  1GZE A;  1GXY A;  1QS1 A;  1GZF A;  4FXQ A;  1GIQ A;  4FML A;  1PWV A;  5GTT A;  4H0T A;  1OG4 A;  4H03 A;  1J7N A;  5H04 A;  4PKU A;  4XM7 A;  4XSG B;  4ELN A;  2C89 A;  2GWL A;  1G24 A;  2A9K B;  1OG1 A;  2WN5 A;  1OG3 A;  4PKQ A;  4GF1 A;  5D1S A;  1QS2 A;  4WF6 A;  4H0Y A;  2C8C A;  4PKS A;  4PKR A;  4XM8 A;  1PWU A;  1ZXV A;  2C8F E;  4PKW A;  5H03 A; 
#chains in the Genus database with same CATH topology
 4H0X A;  1JKY A;  4PKV A;  1OJZ A;  2J3X A;  2WN7 A;  1GY0 A;  2C8B X;  1PWQ A;  4H0V A;  4GY2 A;  2A78 B;  2BOV B;  5BWM B;  2WN4 A;  2J3Z A;  1YQY A;  2C8H A;  5D1U A;  2GWM A;  1PWW A;  4TR5 A;  1GIR A;  4DV8 A;  4FK7 A;  2C8A A;  1PWP A;  2C8D A;  2C8G A;  4XM6 A;  3BUZ A;  2WN8 A;  3BW8 A;  4PKT A;  5D1T A;  5DZQ A;  3NTS A;  2C8E E;  1R45 A;  3U0J A;  4XSH B;  1R4B A;  2J3V A;  1OJQ A;  1GXZ A;  2WN6 A;  1UZI A;  1GZE A;  1GXY A;  1QS1 A;  1GZF A;  4FXQ A;  1GIQ A;  4FML A;  1PWV A;  5GTT A;  4H0T A;  1OG4 A;  4H03 A;  1J7N A;  5H04 A;  4PKU A;  4XM7 A;  4XSG B;  4ELN A;  2C89 A;  2GWL A;  1G24 A;  2A9K B;  1OG1 A;  2WN5 A;  1OG3 A;  4PKQ A;  4GF1 A;  5D1S A;  1QS2 A;  4WF6 A;  4H0Y A;  2C8C A;  4PKS A;  4PKR A;  4XM8 A;  1PWU A;  1ZXV A;  2C8F E;  4PKW A;  5H03 A; 
#chains in the Genus database with same CATH homology
 4H0X A;  1JKY A;  4PKV A;  1OJZ A;  2J3X A;  2WN7 A;  1GY0 A;  2C8B X;  1PWQ A;  4H0V A;  4GY2 A;  2A78 B;  2BOV B;  5BWM B;  2WN4 A;  2J3Z A;  1YQY A;  2C8H A;  5D1U A;  2GWM A;  1PWW A;  4TR5 A;  1GIR A;  4DV8 A;  4FK7 A;  2C8A A;  1PWP A;  2C8D A;  2C8G A;  4XM6 A;  3BUZ A;  2WN8 A;  3BW8 A;  4PKT A;  5D1T A;  5DZQ A;  3NTS A;  2C8E E;  1R45 A;  3U0J A;  4XSH B;  1R4B A;  2J3V A;  1OJQ A;  1GXZ A;  2WN6 A;  1UZI A;  1GZE A;  1GXY A;  1QS1 A;  1GZF A;  4FXQ A;  1GIQ A;  4FML A;  1PWV A;  5GTT A;  4H0T A;  1OG4 A;  4H03 A;  1J7N A;  5H04 A;  4PKU A;  4XM7 A;  4XSG B;  4ELN A;  2C89 A;  2GWL A;  1G24 A;  2A9K B;  1OG1 A;  2WN5 A;  1OG3 A;  4PKQ A;  4GF1 A;  5D1S A;  1QS2 A;  4WF6 A;  4H0Y A;  2C8C A;  4PKS A;  4PKR A;  4XM8 A;  1PWU A;  1ZXV A;  2C8F E;  4PKW A;  5H03 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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