4H03A

Crystal structure of nad+-ia-actin complex
Total Genus 147
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
147
sequence length
414
structure length
414
Chain Sequence
MAFIERPEDFLKDKENAIQWEKKEAERVEKNLDTLEKEALELYKKDSEQISNYSQTRQYFYDYQIESNPREKEYKNLRNAISKNKIDKPINVYYFESPEKFAFNKEIRTENQNEISLEKFNELKETIQDKLFKQDGFKDVSLYEPGNGDEKPTPLLIHLKLPKNTGMLPYINSNDVKTLIEQDYSIKIDKIVRIVIEGKQYIKAEASIVNSLDFKDDVSKGDLWGKENYSDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPLNNPNPELDSKVNNIENALKLTPIPSNLIVYRRSGPQEFGLTLTSPEYDFNKIENIDAFKEKWEGKVITYPNFISTSIGSVNMSAFAKRKIILRINIPKDSPGAYLSAIPGYAGEYEVLLNHGSKFKINKVDSYKDGTVTKLILDATLIN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin/structural protein
molecule keywords Iota toxin component Ia
publication title Arginine ADP-ribosylation mechanism based on structural snapshots of iota-toxin and actin complex
pubmed doi rcsb
source organism Clostridium perfringens
total genus 147
structure length 414
sequence length 414
ec nomenclature ec 2.4.2.31: NAD(+)--protein-arginine ADP-ribosyltransferase.
pdb deposition date 2012-09-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4h03A02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4h03A01
3BW8A 1QS1A 1GXZA 4XSHB 1YQYA 2C8FE 1OG1A 1OG3A 1UZIA 3U0JA 1GIQA 4PKSA 5GTTA 4XM7A 2C8EE 4ELNA 4H03A 1GXYA 2J3VA 1GIRA 1PWVA 5H04A 1PWQA 1PWUA 4WF6A 1OJZA 1PWPA 4XM8A 5DZQA 4H0XA 4XSGB 2GWLA 2C8BX 4H0VA 4GF1A 4FK7A 2WN7A 2C8AA 2C8GA 2BOVB 1G24A 4H0YA 1GZEA 1R45A 1R4BA 2A78B 2GWMA 3BUZA 1JKYA 5D1TA 1OG4A 4GY2A 5D1SA 4TR5A 4PKRA 4XM6A 2WN4A 4H0TA 1J7NA 2C8CA 4FXQA 1QS2A 2WN5A 4PKVA 1GY0A 5D1UA 2WN8A 3NTSA 1ZXVA 2C8HA 2WN6A 1OJQA 2J3ZA 5BWMB 2C8DA 4PKUA 2A9KB 4DV8A 2J3XA 1PWWA 5H03A 4FMLA 4PKQA 4PKWA 4PKTA 1GZFA 2C89A
chains in the Genus database with same CATH superfamily
3BW8A 1QS1A 1GXZA 4XSHB 1YQYA 2C8FE 1OG1A 1OG3A 1UZIA 3U0JA 1GIQA 4PKSA 5GTTA 4XM7A 2C8EE 4ELNA 4H03A 1GXYA 2J3VA 1GIRA 1PWVA 5H04A 1PWQA 1PWUA 4WF6A 1OJZA 1PWPA 4XM8A 5DZQA 4H0XA 4XSGB 2GWLA 2C8BX 4H0VA 4GF1A 4FK7A 2WN7A 2C8AA 2C8GA 2BOVB 1G24A 4H0YA 1GZEA 1R45A 1R4BA 2A78B 2GWMA 3BUZA 1JKYA 5D1TA 1OG4A 4GY2A 5D1SA 4TR5A 4PKRA 4XM6A 2WN4A 4H0TA 1J7NA 2C8CA 4FXQA 1QS2A 2WN5A 4PKVA 1GY0A 5D1UA 2WN8A 3NTSA 1ZXVA 2C8HA 2WN6A 1OJQA 2J3ZA 5BWMB 2C8DA 4PKUA 2A9KB 4DV8A 2J3XA 1PWWA 5H03A 4FMLA 4PKQA 4PKWA 4PKTA 1GZFA 2C89A
chains in the Genus database with same CATH topology
3BW8A 1QS1A 1GXZA 4XSHB 1YQYA 2C8FE 1OG1A 1OG3A 1UZIA 3U0JA 1GIQA 4PKSA 5GTTA 4XM7A 2C8EE 4ELNA 4H03A 1GXYA 2J3VA 1GIRA 1PWVA 5H04A 1PWQA 1PWUA 4WF6A 1OJZA 1PWPA 4XM8A 5DZQA 4H0XA 4XSGB 2GWLA 2C8BX 4H0VA 4GF1A 4FK7A 2WN7A 2C8AA 2C8GA 2BOVB 1G24A 4H0YA 1GZEA 1R45A 1R4BA 2A78B 2GWMA 3BUZA 1JKYA 5D1TA 1OG4A 4GY2A 5D1SA 4TR5A 4PKRA 4XM6A 2WN4A 4H0TA 1J7NA 2C8CA 4FXQA 1QS2A 2WN5A 4PKVA 1GY0A 5D1UA 2WN8A 3NTSA 1ZXVA 2C8HA 2WN6A 1OJQA 2J3ZA 5BWMB 2C8DA 4PKUA 2A9KB 4DV8A 2J3XA 1PWWA 5H03A 4FMLA 4PKQA 4PKWA 4PKTA 1GZFA 2C89A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BW8 A;  1QS1 A;  1GXZ A;  4XSH B;  1YQY A;  2C8F E;  1OG1 A;  1OG3 A;  1UZI A;  3U0J A;  1GIQ A;  4PKS A;  5GTT A;  4XM7 A;  2C8E E;  4ELN A;  4H03 A;  1GXY A;  2J3V A;  1GIR A;  1PWV A;  5H04 A;  1PWQ A;  1PWU A;  4WF6 A;  1OJZ A;  1PWP A;  4XM8 A;  5DZQ A;  4H0X A;  4XSG B;  2GWL A;  2C8B X;  4H0V A;  4GF1 A;  4FK7 A;  2WN7 A;  2C8A A;  2C8G A;  2BOV B;  1G24 A;  4H0Y A;  1GZE A;  1R45 A;  1R4B A;  2A78 B;  2GWM A;  3BUZ A;  1JKY A;  5D1T A;  1OG4 A;  4GY2 A;  5D1S A;  4TR5 A;  4PKR A;  4XM6 A;  2WN4 A;  4H0T A;  1J7N A;  2C8C A;  4FXQ A;  1QS2 A;  2WN5 A;  4PKV A;  1GY0 A;  5D1U A;  2WN8 A;  3NTS A;  1ZXV A;  2C8H A;  2WN6 A;  1OJQ A;  2J3Z A;  5BWM B;  2C8D A;  4PKU A;  2A9K B;  4DV8 A;  2J3X A;  1PWW A;  5H03 A;  4FML A;  4PKQ A;  4PKW A;  4PKT A;  1GZF A;  2C89 A; 
#chains in the Genus database with same CATH topology
 3BW8 A;  1QS1 A;  1GXZ A;  4XSH B;  1YQY A;  2C8F E;  1OG1 A;  1OG3 A;  1UZI A;  3U0J A;  1GIQ A;  4PKS A;  5GTT A;  4XM7 A;  2C8E E;  4ELN A;  4H03 A;  1GXY A;  2J3V A;  1GIR A;  1PWV A;  5H04 A;  1PWQ A;  1PWU A;  4WF6 A;  1OJZ A;  1PWP A;  4XM8 A;  5DZQ A;  4H0X A;  4XSG B;  2GWL A;  2C8B X;  4H0V A;  4GF1 A;  4FK7 A;  2WN7 A;  2C8A A;  2C8G A;  2BOV B;  1G24 A;  4H0Y A;  1GZE A;  1R45 A;  1R4B A;  2A78 B;  2GWM A;  3BUZ A;  1JKY A;  5D1T A;  1OG4 A;  4GY2 A;  5D1S A;  4TR5 A;  4PKR A;  4XM6 A;  2WN4 A;  4H0T A;  1J7N A;  2C8C A;  4FXQ A;  1QS2 A;  2WN5 A;  4PKV A;  1GY0 A;  5D1U A;  2WN8 A;  3NTS A;  1ZXV A;  2C8H A;  2WN6 A;  1OJQ A;  2J3Z A;  5BWM B;  2C8D A;  4PKU A;  2A9K B;  4DV8 A;  2J3X A;  1PWW A;  5H03 A;  4FML A;  4PKQ A;  4PKW A;  4PKT A;  1GZF A;  2C89 A; 
#chains in the Genus database with same CATH homology
 3BW8 A;  1QS1 A;  1GXZ A;  4XSH B;  1YQY A;  2C8F E;  1OG1 A;  1OG3 A;  1UZI A;  3U0J A;  1GIQ A;  4PKS A;  5GTT A;  4XM7 A;  2C8E E;  4ELN A;  4H03 A;  1GXY A;  2J3V A;  1GIR A;  1PWV A;  5H04 A;  1PWQ A;  1PWU A;  4WF6 A;  1OJZ A;  1PWP A;  4XM8 A;  5DZQ A;  4H0X A;  4XSG B;  2GWL A;  2C8B X;  4H0V A;  4GF1 A;  4FK7 A;  2WN7 A;  2C8A A;  2C8G A;  2BOV B;  1G24 A;  4H0Y A;  1GZE A;  1R45 A;  1R4B A;  2A78 B;  2GWM A;  3BUZ A;  1JKY A;  5D1T A;  1OG4 A;  4GY2 A;  5D1S A;  4TR5 A;  4PKR A;  4XM6 A;  2WN4 A;  4H0T A;  1J7N A;  2C8C A;  4FXQ A;  1QS2 A;  2WN5 A;  4PKV A;  1GY0 A;  5D1U A;  2WN8 A;  3NTS A;  1ZXV A;  2C8H A;  2WN6 A;  1OJQ A;  2J3Z A;  5BWM B;  2C8D A;  4PKU A;  2A9K B;  4DV8 A;  2J3X A;  1PWW A;  5H03 A;  4FML A;  4PKQ A;  4PKW A;  4PKT A;  1GZF A;  2C89 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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