4H0VA

Crystal structure of nad+-ia(e378s)-actin complex
Total Genus 147
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
147
sequence length
413
structure length
413
Chain Sequence
AFIERPEDFLKDKENAIQWEKKEAERVEKNLDTLEKEALELYKKDSEQISNYSQTRQYFYDYQIESNPREKEYKNLRNAISKNKIDKPINVYYFESPEKFAFNKEIRTENQNEISLEKFNELKETIQDKLFKQDGFKDVSLYEPGNGDEKPTPLLIHLKLPKNTGMLPYINSNDVKTLIEQDYSIKIDKIVRIVIEGKQYIKAEASIVNSLDFKDDVSKGDLWGKENYSDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPLNNPNPELDSKVNNIENALKLTPIPSNLIVYRRSGPQEFGLTLTSPEYDFNKIENIDAFKEKWEGKVITYPNFISTSIGSVNMSAFAKRKIILRINIPKDSPGAYLSAIPGYAGSYEVLLNHGSKFKINKVDSYKDGTVTKLILDATLIN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin/structural protein
molecule keywords Iota toxin component Ia
publication title Arginine ADP-ribosylation mechanism based on structural snapshots of iota-toxin and actin complex
pubmed doi rcsb
source organism Clostridium perfringens
total genus 147
structure length 413
sequence length 413
ec nomenclature ec 2.4.2.31: NAD(+)--protein-arginine ADP-ribosyltransferase.
pdb deposition date 2012-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4h0vA02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4h0vA01
1OG3A 1R45A 2A9KB 1OJZA 4GF1A 2C8FE 1GIRA 1YQYA 2WN4A 1GXYA 1QS2A 4XSHB 5DZQA 2GWLA 2J3ZA 1OJQA 3BUZA 2C8DA 4H0YA 4PKQA 4DV8A 4XSGB 4XM7A 4H0XA 1R4BA 2WN6A 5D1UA 1PWPA 1GIQA 4TR5A 2BOVB 4ELNA 1PWUA 5H03A 2J3XA 4PKRA 5GTTA 1OG4A 4H03A 2C8BX 1ZXVA 5D1SA 4H0VA 1OG1A 3NTSA 2J3VA 1PWVA 2C8CA 3U0JA 2C89A 4PKWA 2C8EE 4WF6A 4PKTA 5BWMB 2WN8A 4XM6A 4FMLA 4XM8A 4PKSA 1GZEA 2C8HA 5D1TA 1PWWA 1QS1A 4FXQA 5H04A 1GY0A 1UZIA 4FK7A 1G24A 1GZFA 2WN5A 1JKYA 4PKUA 1PWQA 2C8GA 3BW8A 4PKVA 2WN7A 1GXZA 2GWMA 4H0TA 1J7NA 4GY2A 2C8AA 2A78B
chains in the Genus database with same CATH superfamily
1OG3A 1R45A 2A9KB 1OJZA 4GF1A 2C8FE 1GIRA 1YQYA 2WN4A 1GXYA 1QS2A 4XSHB 5DZQA 2GWLA 2J3ZA 1OJQA 3BUZA 2C8DA 4H0YA 4PKQA 4DV8A 4XSGB 4XM7A 4H0XA 1R4BA 2WN6A 5D1UA 1PWPA 1GIQA 4TR5A 2BOVB 4ELNA 1PWUA 5H03A 2J3XA 4PKRA 5GTTA 1OG4A 4H03A 2C8BX 1ZXVA 5D1SA 4H0VA 1OG1A 3NTSA 2J3VA 1PWVA 2C8CA 3U0JA 2C89A 4PKWA 2C8EE 4WF6A 4PKTA 5BWMB 2WN8A 4XM6A 4FMLA 4XM8A 4PKSA 1GZEA 2C8HA 5D1TA 1PWWA 1QS1A 4FXQA 5H04A 1GY0A 1UZIA 4FK7A 1G24A 1GZFA 2WN5A 1JKYA 4PKUA 1PWQA 2C8GA 3BW8A 4PKVA 2WN7A 1GXZA 2GWMA 4H0TA 1J7NA 4GY2A 2C8AA 2A78B
chains in the Genus database with same CATH topology
1OG3A 1R45A 2A9KB 1OJZA 4GF1A 2C8FE 1GIRA 1YQYA 2WN4A 1GXYA 1QS2A 4XSHB 5DZQA 2GWLA 2J3ZA 1OJQA 3BUZA 2C8DA 4H0YA 4PKQA 4DV8A 4XSGB 4XM7A 4H0XA 1R4BA 2WN6A 5D1UA 1PWPA 1GIQA 4TR5A 2BOVB 4ELNA 1PWUA 5H03A 2J3XA 4PKRA 5GTTA 1OG4A 4H03A 2C8BX 1ZXVA 5D1SA 4H0VA 1OG1A 3NTSA 2J3VA 1PWVA 2C8CA 3U0JA 2C89A 4PKWA 2C8EE 4WF6A 4PKTA 5BWMB 2WN8A 4XM6A 4FMLA 4XM8A 4PKSA 1GZEA 2C8HA 5D1TA 1PWWA 1QS1A 4FXQA 5H04A 1GY0A 1UZIA 4FK7A 1G24A 1GZFA 2WN5A 1JKYA 4PKUA 1PWQA 2C8GA 3BW8A 4PKVA 2WN7A 1GXZA 2GWMA 4H0TA 1J7NA 4GY2A 2C8AA 2A78B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OG3 A;  1R45 A;  2A9K B;  1OJZ A;  4GF1 A;  2C8F E;  1GIR A;  1YQY A;  2WN4 A;  1GXY A;  1QS2 A;  4XSH B;  5DZQ A;  2GWL A;  2J3Z A;  1OJQ A;  3BUZ A;  2C8D A;  4H0Y A;  4PKQ A;  4DV8 A;  4XSG B;  4XM7 A;  4H0X A;  1R4B A;  2WN6 A;  5D1U A;  1PWP A;  1GIQ A;  4TR5 A;  2BOV B;  4ELN A;  1PWU A;  5H03 A;  2J3X A;  4PKR A;  5GTT A;  1OG4 A;  4H03 A;  2C8B X;  1ZXV A;  5D1S A;  4H0V A;  1OG1 A;  3NTS A;  2J3V A;  1PWV A;  2C8C A;  3U0J A;  2C89 A;  4PKW A;  2C8E E;  4WF6 A;  4PKT A;  5BWM B;  2WN8 A;  4XM6 A;  4FML A;  4XM8 A;  4PKS A;  1GZE A;  2C8H A;  5D1T A;  1PWW A;  1QS1 A;  4FXQ A;  5H04 A;  1GY0 A;  1UZI A;  4FK7 A;  1G24 A;  1GZF A;  2WN5 A;  1JKY A;  4PKU A;  1PWQ A;  2C8G A;  3BW8 A;  4PKV A;  2WN7 A;  1GXZ A;  2GWM A;  4H0T A;  1J7N A;  4GY2 A;  2C8A A;  2A78 B; 
#chains in the Genus database with same CATH topology
 1OG3 A;  1R45 A;  2A9K B;  1OJZ A;  4GF1 A;  2C8F E;  1GIR A;  1YQY A;  2WN4 A;  1GXY A;  1QS2 A;  4XSH B;  5DZQ A;  2GWL A;  2J3Z A;  1OJQ A;  3BUZ A;  2C8D A;  4H0Y A;  4PKQ A;  4DV8 A;  4XSG B;  4XM7 A;  4H0X A;  1R4B A;  2WN6 A;  5D1U A;  1PWP A;  1GIQ A;  4TR5 A;  2BOV B;  4ELN A;  1PWU A;  5H03 A;  2J3X A;  4PKR A;  5GTT A;  1OG4 A;  4H03 A;  2C8B X;  1ZXV A;  5D1S A;  4H0V A;  1OG1 A;  3NTS A;  2J3V A;  1PWV A;  2C8C A;  3U0J A;  2C89 A;  4PKW A;  2C8E E;  4WF6 A;  4PKT A;  5BWM B;  2WN8 A;  4XM6 A;  4FML A;  4XM8 A;  4PKS A;  1GZE A;  2C8H A;  5D1T A;  1PWW A;  1QS1 A;  4FXQ A;  5H04 A;  1GY0 A;  1UZI A;  4FK7 A;  1G24 A;  1GZF A;  2WN5 A;  1JKY A;  4PKU A;  1PWQ A;  2C8G A;  3BW8 A;  4PKV A;  2WN7 A;  1GXZ A;  2GWM A;  4H0T A;  1J7N A;  4GY2 A;  2C8A A;  2A78 B; 
#chains in the Genus database with same CATH homology
 1OG3 A;  1R45 A;  2A9K B;  1OJZ A;  4GF1 A;  2C8F E;  1GIR A;  1YQY A;  2WN4 A;  1GXY A;  1QS2 A;  4XSH B;  5DZQ A;  2GWL A;  2J3Z A;  1OJQ A;  3BUZ A;  2C8D A;  4H0Y A;  4PKQ A;  4DV8 A;  4XSG B;  4XM7 A;  4H0X A;  1R4B A;  2WN6 A;  5D1U A;  1PWP A;  1GIQ A;  4TR5 A;  2BOV B;  4ELN A;  1PWU A;  5H03 A;  2J3X A;  4PKR A;  5GTT A;  1OG4 A;  4H03 A;  2C8B X;  1ZXV A;  5D1S A;  4H0V A;  1OG1 A;  3NTS A;  2J3V A;  1PWV A;  2C8C A;  3U0J A;  2C89 A;  4PKW A;  2C8E E;  4WF6 A;  4PKT A;  5BWM B;  2WN8 A;  4XM6 A;  4FML A;  4XM8 A;  4PKS A;  1GZE A;  2C8H A;  5D1T A;  1PWW A;  1QS1 A;  4FXQ A;  5H04 A;  1GY0 A;  1UZI A;  4FK7 A;  1G24 A;  1GZF A;  2WN5 A;  1JKY A;  4PKU A;  1PWQ A;  2C8G A;  3BW8 A;  4PKV A;  2WN7 A;  1GXZ A;  2GWM A;  4H0T A;  1J7N A;  4GY2 A;  2C8A A;  2A78 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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