4GY2A

Crystal structure of apo-ia-actin complex
Total Genus 137
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
137
sequence length
411
structure length
411
Chain Sequence
IERPEDFLKDKENAIQWEKKEAERVEKNLDTLEKEALELYKKDSEQISNYSQTRQYFYDYQIESNPREKEYKNLRNAISKNKIDKPINVYYFESPEKFAFNKEIRTENQNEISLEKFNELKETIQDKLFKQDGFKDVSLYEPGNGDEKPTPLLIHLKLPKNTGMLPYINSNDVKTLIEQDYSIKIDKIVRIVIEGKQYIKAEASIVNSLDFKDDVSKGDLWGKENYSDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPLNNPNPELDSKVNNIENALKLTPIPSNLIVYRRSGPQEFGLTLTSPEYDFNKIENIDAFKEKWEGKVITYPNFISTSIGSVNMSAFAKRKIILRINIPKDSPGAYLSAIPGYAGEYEVLLNHGSKFKINKVDSYKDGTVTKLILDATLIN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Iota toxin component Ia
publication title Arginine ADP-ribosylation mechanism based on structural snapshots of iota-toxin and actin complex
pubmed doi rcsb
source organism Clostridium perfringens
molecule tags Toxin/structural protein
total genus 137
structure length 411
sequence length 411
ec nomenclature ec 2.4.2.31: NAD(+)--protein-arginine ADP-ribosyltransferase.
pdb deposition date 2012-09-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4gy2A02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4gy2A01
1PWWA 2C8FE 4DV8A 1GIRA 4H03A 5DZQA 1GXZA 1QS1A 1OG3A 2C8CA 5H04A 4ELNA 4XSHB 2C8EE 1UZIA 1J7NA 2WN5A 2C89A 1PWVA 2C8BX 4H0VA 4WF6A 1GZFA 5D1TA 4XM6A 1GZEA 2J3VA 1OG4A 4PKQA 2C8GA 4H0XA 2WN6A 1G24A 4PKRA 1PWUA 4FMLA 5D1UA 1YQYA 4H0TA 1OJQA 4PKUA 2GWMA 2BOVB 1GIQA 4PKSA 4FXQA 2C8AA 2WN7A 1R4BA 2J3ZA 3NTSA 2GWLA 1R45A 1ZXVA 1JKYA 4PKTA 2A78B 1PWQA 4GF1A 1GXYA 3BUZA 5H03A 3U0JA 5GTTA 3BW8A 4FK7A 2WN4A 2J3XA 4PKVA 4TR5A 2C8DA 4XM8A 5D1SA 1PWPA 4H0YA 2A9KB 2C8HA 2WN8A 1GY0A 1OG1A 1OJZA 4XSGB 1QS2A 4XM7A 4GY2A 4PKWA 5BWMB
chains in the Genus database with same CATH superfamily
1PWWA 2C8FE 4DV8A 1GIRA 4H03A 5DZQA 1GXZA 1QS1A 1OG3A 2C8CA 5H04A 4ELNA 4XSHB 2C8EE 1UZIA 1J7NA 2WN5A 2C89A 1PWVA 2C8BX 4H0VA 4WF6A 1GZFA 5D1TA 4XM6A 1GZEA 2J3VA 1OG4A 4PKQA 2C8GA 4H0XA 2WN6A 1G24A 4PKRA 1PWUA 4FMLA 5D1UA 1YQYA 4H0TA 1OJQA 4PKUA 2GWMA 2BOVB 1GIQA 4PKSA 4FXQA 2C8AA 2WN7A 1R4BA 2J3ZA 3NTSA 2GWLA 1R45A 1ZXVA 1JKYA 4PKTA 2A78B 1PWQA 4GF1A 1GXYA 3BUZA 5H03A 3U0JA 5GTTA 3BW8A 4FK7A 2WN4A 2J3XA 4PKVA 4TR5A 2C8DA 4XM8A 5D1SA 1PWPA 4H0YA 2A9KB 2C8HA 2WN8A 1GY0A 1OG1A 1OJZA 4XSGB 1QS2A 4XM7A 4GY2A 4PKWA 5BWMB
chains in the Genus database with same CATH topology
1PWWA 2C8FE 4DV8A 1GIRA 4H03A 5DZQA 1GXZA 1QS1A 1OG3A 2C8CA 5H04A 4ELNA 4XSHB 2C8EE 1UZIA 1J7NA 2WN5A 2C89A 1PWVA 2C8BX 4H0VA 4WF6A 1GZFA 5D1TA 4XM6A 1GZEA 2J3VA 1OG4A 4PKQA 2C8GA 4H0XA 2WN6A 1G24A 4PKRA 1PWUA 4FMLA 5D1UA 1YQYA 4H0TA 1OJQA 4PKUA 2GWMA 2BOVB 1GIQA 4PKSA 4FXQA 2C8AA 2WN7A 1R4BA 2J3ZA 3NTSA 2GWLA 1R45A 1ZXVA 1JKYA 4PKTA 2A78B 1PWQA 4GF1A 1GXYA 3BUZA 5H03A 3U0JA 5GTTA 3BW8A 4FK7A 2WN4A 2J3XA 4PKVA 4TR5A 2C8DA 4XM8A 5D1SA 1PWPA 4H0YA 2A9KB 2C8HA 2WN8A 1GY0A 1OG1A 1OJZA 4XSGB 1QS2A 4XM7A 4GY2A 4PKWA 5BWMB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PWW A;  2C8F E;  4DV8 A;  1GIR A;  4H03 A;  5DZQ A;  1GXZ A;  1QS1 A;  1OG3 A;  2C8C A;  5H04 A;  4ELN A;  4XSH B;  2C8E E;  1UZI A;  1J7N A;  2WN5 A;  2C89 A;  1PWV A;  2C8B X;  4H0V A;  4WF6 A;  1GZF A;  5D1T A;  4XM6 A;  1GZE A;  2J3V A;  1OG4 A;  4PKQ A;  2C8G A;  4H0X A;  2WN6 A;  1G24 A;  4PKR A;  1PWU A;  4FML A;  5D1U A;  1YQY A;  4H0T A;  1OJQ A;  4PKU A;  2GWM A;  2BOV B;  1GIQ A;  4PKS A;  4FXQ A;  2C8A A;  2WN7 A;  1R4B A;  2J3Z A;  3NTS A;  2GWL A;  1R45 A;  1ZXV A;  1JKY A;  4PKT A;  2A78 B;  1PWQ A;  4GF1 A;  1GXY A;  3BUZ A;  5H03 A;  3U0J A;  5GTT A;  3BW8 A;  4FK7 A;  2WN4 A;  2J3X A;  4PKV A;  4TR5 A;  2C8D A;  4XM8 A;  5D1S A;  1PWP A;  4H0Y A;  2A9K B;  2C8H A;  2WN8 A;  1GY0 A;  1OG1 A;  1OJZ A;  4XSG B;  1QS2 A;  4XM7 A;  4GY2 A;  4PKW A;  5BWM B; 
#chains in the Genus database with same CATH topology
 1PWW A;  2C8F E;  4DV8 A;  1GIR A;  4H03 A;  5DZQ A;  1GXZ A;  1QS1 A;  1OG3 A;  2C8C A;  5H04 A;  4ELN A;  4XSH B;  2C8E E;  1UZI A;  1J7N A;  2WN5 A;  2C89 A;  1PWV A;  2C8B X;  4H0V A;  4WF6 A;  1GZF A;  5D1T A;  4XM6 A;  1GZE A;  2J3V A;  1OG4 A;  4PKQ A;  2C8G A;  4H0X A;  2WN6 A;  1G24 A;  4PKR A;  1PWU A;  4FML A;  5D1U A;  1YQY A;  4H0T A;  1OJQ A;  4PKU A;  2GWM A;  2BOV B;  1GIQ A;  4PKS A;  4FXQ A;  2C8A A;  2WN7 A;  1R4B A;  2J3Z A;  3NTS A;  2GWL A;  1R45 A;  1ZXV A;  1JKY A;  4PKT A;  2A78 B;  1PWQ A;  4GF1 A;  1GXY A;  3BUZ A;  5H03 A;  3U0J A;  5GTT A;  3BW8 A;  4FK7 A;  2WN4 A;  2J3X A;  4PKV A;  4TR5 A;  2C8D A;  4XM8 A;  5D1S A;  1PWP A;  4H0Y A;  2A9K B;  2C8H A;  2WN8 A;  1GY0 A;  1OG1 A;  1OJZ A;  4XSG B;  1QS2 A;  4XM7 A;  4GY2 A;  4PKW A;  5BWM B; 
#chains in the Genus database with same CATH homology
 1PWW A;  2C8F E;  4DV8 A;  1GIR A;  4H03 A;  5DZQ A;  1GXZ A;  1QS1 A;  1OG3 A;  2C8C A;  5H04 A;  4ELN A;  4XSH B;  2C8E E;  1UZI A;  1J7N A;  2WN5 A;  2C89 A;  1PWV A;  2C8B X;  4H0V A;  4WF6 A;  1GZF A;  5D1T A;  4XM6 A;  1GZE A;  2J3V A;  1OG4 A;  4PKQ A;  2C8G A;  4H0X A;  2WN6 A;  1G24 A;  4PKR A;  1PWU A;  4FML A;  5D1U A;  1YQY A;  4H0T A;  1OJQ A;  4PKU A;  2GWM A;  2BOV B;  1GIQ A;  4PKS A;  4FXQ A;  2C8A A;  2WN7 A;  1R4B A;  2J3Z A;  3NTS A;  2GWL A;  1R45 A;  1ZXV A;  1JKY A;  4PKT A;  2A78 B;  1PWQ A;  4GF1 A;  1GXY A;  3BUZ A;  5H03 A;  3U0J A;  5GTT A;  3BW8 A;  4FK7 A;  2WN4 A;  2J3X A;  4PKV A;  4TR5 A;  2C8D A;  4XM8 A;  5D1S A;  1PWP A;  4H0Y A;  2A9K B;  2C8H A;  2WN8 A;  1GY0 A;  1OG1 A;  1OJZ A;  4XSG B;  1QS2 A;  4XM7 A;  4GY2 A;  4PKW A;  5BWM B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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