4GY2A

Crystal structure of apo-ia-actin complex
Total Genus 137
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
137
sequence length
411
structure length
411
Chain Sequence
IERPEDFLKDKENAIQWEKKEAERVEKNLDTLEKEALELYKKDSEQISNYSQTRQYFYDYQIESNPREKEYKNLRNAISKNKIDKPINVYYFESPEKFAFNKEIRTENQNEISLEKFNELKETIQDKLFKQDGFKDVSLYEPGNGDEKPTPLLIHLKLPKNTGMLPYINSNDVKTLIEQDYSIKIDKIVRIVIEGKQYIKAEASIVNSLDFKDDVSKGDLWGKENYSDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPLNNPNPELDSKVNNIENALKLTPIPSNLIVYRRSGPQEFGLTLTSPEYDFNKIENIDAFKEKWEGKVITYPNFISTSIGSVNMSAFAKRKIILRINIPKDSPGAYLSAIPGYAGEYEVLLNHGSKFKINKVDSYKDGTVTKLILDATLIN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin/structural protein
molecule keywords Iota toxin component Ia
publication title Arginine ADP-ribosylation mechanism based on structural snapshots of iota-toxin and actin complex
pubmed doi rcsb
source organism Clostridium perfringens
total genus 137
structure length 411
sequence length 411
ec nomenclature ec 2.4.2.31: NAD(+)--protein-arginine ADP-ribosyltransferase.
pdb deposition date 2012-09-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4gy2A02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4gy2A01
5BWMB 1GZEA 4PKSA 3BUZA 1QS2A 2C8EE 4GY2A 4XM7A 1JKYA 4PKTA 1QS1A 4FXQA 4H0VA 4XM6A 1PWQA 1OG1A 2C89A 1GXZA 4PKUA 3U0JA 1OG3A 4PKQA 4XSHB 2WN6A 5GTTA 2A9KB 4H0TA 4TR5A 1PWPA 1GY0A 1R4BA 1OJQA 2WN8A 2BOVB 2GWLA 2C8BX 1G24A 3NTSA 5D1UA 5H04A 4H0XA 2C8AA 2J3ZA 1J7NA 1GZFA 2WN4A 4WF6A 1GXYA 2J3VA 1OG4A 5DZQA 4PKWA 1YQYA 1UZIA 1PWVA 1GIQA 2WN5A 4PKRA 4ELNA 2WN7A 4GF1A 2C8FE 5H03A 2J3XA 4FK7A 4H03A 4H0YA 4XM8A 2C8HA 1PWWA 2C8CA 2C8DA 1PWUA 3BW8A 4XSGB 4FMLA 1R45A 2A78B 2GWMA 5D1TA 4DV8A 1ZXVA 1OJZA 4PKVA 5D1SA 1GIRA 2C8GA
chains in the Genus database with same CATH superfamily
5BWMB 1GZEA 4PKSA 3BUZA 1QS2A 2C8EE 4GY2A 4XM7A 1JKYA 4PKTA 1QS1A 4FXQA 4H0VA 4XM6A 1PWQA 1OG1A 2C89A 1GXZA 4PKUA 3U0JA 1OG3A 4PKQA 4XSHB 2WN6A 5GTTA 2A9KB 4H0TA 4TR5A 1PWPA 1GY0A 1R4BA 1OJQA 2WN8A 2BOVB 2GWLA 2C8BX 1G24A 3NTSA 5D1UA 5H04A 4H0XA 2C8AA 2J3ZA 1J7NA 1GZFA 2WN4A 4WF6A 1GXYA 2J3VA 1OG4A 5DZQA 4PKWA 1YQYA 1UZIA 1PWVA 1GIQA 2WN5A 4PKRA 4ELNA 2WN7A 4GF1A 2C8FE 5H03A 2J3XA 4FK7A 4H03A 4H0YA 4XM8A 2C8HA 1PWWA 2C8CA 2C8DA 1PWUA 3BW8A 4XSGB 4FMLA 1R45A 2A78B 2GWMA 5D1TA 4DV8A 1ZXVA 1OJZA 4PKVA 5D1SA 1GIRA 2C8GA
chains in the Genus database with same CATH topology
5BWMB 1GZEA 4PKSA 3BUZA 1QS2A 2C8EE 4GY2A 4XM7A 1JKYA 4PKTA 1QS1A 4FXQA 4H0VA 4XM6A 1PWQA 1OG1A 2C89A 1GXZA 4PKUA 3U0JA 1OG3A 4PKQA 4XSHB 2WN6A 5GTTA 2A9KB 4H0TA 4TR5A 1PWPA 1GY0A 1R4BA 1OJQA 2WN8A 2BOVB 2GWLA 2C8BX 1G24A 3NTSA 5D1UA 5H04A 4H0XA 2C8AA 2J3ZA 1J7NA 1GZFA 2WN4A 4WF6A 1GXYA 2J3VA 1OG4A 5DZQA 4PKWA 1YQYA 1UZIA 1PWVA 1GIQA 2WN5A 4PKRA 4ELNA 2WN7A 4GF1A 2C8FE 5H03A 2J3XA 4FK7A 4H03A 4H0YA 4XM8A 2C8HA 1PWWA 2C8CA 2C8DA 1PWUA 3BW8A 4XSGB 4FMLA 1R45A 2A78B 2GWMA 5D1TA 4DV8A 1ZXVA 1OJZA 4PKVA 5D1SA 1GIRA 2C8GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5BWM B;  1GZE A;  4PKS A;  3BUZ A;  1QS2 A;  2C8E E;  4GY2 A;  4XM7 A;  1JKY A;  4PKT A;  1QS1 A;  4FXQ A;  4H0V A;  4XM6 A;  1PWQ A;  1OG1 A;  2C89 A;  1GXZ A;  4PKU A;  3U0J A;  1OG3 A;  4PKQ A;  4XSH B;  2WN6 A;  5GTT A;  2A9K B;  4H0T A;  4TR5 A;  1PWP A;  1GY0 A;  1R4B A;  1OJQ A;  2WN8 A;  2BOV B;  2GWL A;  2C8B X;  1G24 A;  3NTS A;  5D1U A;  5H04 A;  4H0X A;  2C8A A;  2J3Z A;  1J7N A;  1GZF A;  2WN4 A;  4WF6 A;  1GXY A;  2J3V A;  1OG4 A;  5DZQ A;  4PKW A;  1YQY A;  1UZI A;  1PWV A;  1GIQ A;  2WN5 A;  4PKR A;  4ELN A;  2WN7 A;  4GF1 A;  2C8F E;  5H03 A;  2J3X A;  4FK7 A;  4H03 A;  4H0Y A;  4XM8 A;  2C8H A;  1PWW A;  2C8C A;  2C8D A;  1PWU A;  3BW8 A;  4XSG B;  4FML A;  1R45 A;  2A78 B;  2GWM A;  5D1T A;  4DV8 A;  1ZXV A;  1OJZ A;  4PKV A;  5D1S A;  1GIR A;  2C8G A; 
#chains in the Genus database with same CATH topology
 5BWM B;  1GZE A;  4PKS A;  3BUZ A;  1QS2 A;  2C8E E;  4GY2 A;  4XM7 A;  1JKY A;  4PKT A;  1QS1 A;  4FXQ A;  4H0V A;  4XM6 A;  1PWQ A;  1OG1 A;  2C89 A;  1GXZ A;  4PKU A;  3U0J A;  1OG3 A;  4PKQ A;  4XSH B;  2WN6 A;  5GTT A;  2A9K B;  4H0T A;  4TR5 A;  1PWP A;  1GY0 A;  1R4B A;  1OJQ A;  2WN8 A;  2BOV B;  2GWL A;  2C8B X;  1G24 A;  3NTS A;  5D1U A;  5H04 A;  4H0X A;  2C8A A;  2J3Z A;  1J7N A;  1GZF A;  2WN4 A;  4WF6 A;  1GXY A;  2J3V A;  1OG4 A;  5DZQ A;  4PKW A;  1YQY A;  1UZI A;  1PWV A;  1GIQ A;  2WN5 A;  4PKR A;  4ELN A;  2WN7 A;  4GF1 A;  2C8F E;  5H03 A;  2J3X A;  4FK7 A;  4H03 A;  4H0Y A;  4XM8 A;  2C8H A;  1PWW A;  2C8C A;  2C8D A;  1PWU A;  3BW8 A;  4XSG B;  4FML A;  1R45 A;  2A78 B;  2GWM A;  5D1T A;  4DV8 A;  1ZXV A;  1OJZ A;  4PKV A;  5D1S A;  1GIR A;  2C8G A; 
#chains in the Genus database with same CATH homology
 5BWM B;  1GZE A;  4PKS A;  3BUZ A;  1QS2 A;  2C8E E;  4GY2 A;  4XM7 A;  1JKY A;  4PKT A;  1QS1 A;  4FXQ A;  4H0V A;  4XM6 A;  1PWQ A;  1OG1 A;  2C89 A;  1GXZ A;  4PKU A;  3U0J A;  1OG3 A;  4PKQ A;  4XSH B;  2WN6 A;  5GTT A;  2A9K B;  4H0T A;  4TR5 A;  1PWP A;  1GY0 A;  1R4B A;  1OJQ A;  2WN8 A;  2BOV B;  2GWL A;  2C8B X;  1G24 A;  3NTS A;  5D1U A;  5H04 A;  4H0X A;  2C8A A;  2J3Z A;  1J7N A;  1GZF A;  2WN4 A;  4WF6 A;  1GXY A;  2J3V A;  1OG4 A;  5DZQ A;  4PKW A;  1YQY A;  1UZI A;  1PWV A;  1GIQ A;  2WN5 A;  4PKR A;  4ELN A;  2WN7 A;  4GF1 A;  2C8F E;  5H03 A;  2J3X A;  4FK7 A;  4H03 A;  4H0Y A;  4XM8 A;  2C8H A;  1PWW A;  2C8C A;  2C8D A;  1PWU A;  3BW8 A;  4XSG B;  4FML A;  1R45 A;  2A78 B;  2GWM A;  5D1T A;  4DV8 A;  1ZXV A;  1OJZ A;  4PKV A;  5D1S A;  1GIR A;  2C8G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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