4GY2A

Crystal structure of apo-ia-actin complex
Total Genus 137
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
137
sequence length
411
structure length
411
Chain Sequence
IERPEDFLKDKENAIQWEKKEAERVEKNLDTLEKEALELYKKDSEQISNYSQTRQYFYDYQIESNPREKEYKNLRNAISKNKIDKPINVYYFESPEKFAFNKEIRTENQNEISLEKFNELKETIQDKLFKQDGFKDVSLYEPGNGDEKPTPLLIHLKLPKNTGMLPYINSNDVKTLIEQDYSIKIDKIVRIVIEGKQYIKAEASIVNSLDFKDDVSKGDLWGKENYSDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPLNNPNPELDSKVNNIENALKLTPIPSNLIVYRRSGPQEFGLTLTSPEYDFNKIENIDAFKEKWEGKVITYPNFISTSIGSVNMSAFAKRKIILRINIPKDSPGAYLSAIPGYAGEYEVLLNHGSKFKINKVDSYKDGTVTKLILDATLIN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Arginine ADP-ribosylation mechanism based on structural snapshots of iota-toxin and actin complex
pubmed doi rcsb
molecule tags Toxin/structural protein
source organism Clostridium perfringens
molecule keywords Iota toxin component Ia
total genus 137
structure length 411
sequence length 411
ec nomenclature ec 2.4.2.31: NAD(+)--protein-arginine ADP-ribosyltransferase.
pdb deposition date 2012-09-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4gy2A02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4gy2A01
1GZEA 1OJZA 4XM7A 1GY0A 1OG1A 1ZXVA 4XM8A 4PKTA 2BOVB 1YQYA 2WN7A 5GTTA 2WN4A 1GZFA 5BWMB 2J3XA 5DZQA 2J3ZA 2C8BX 4WF6A 2A78B 4PKQA 2WN8A 4PKSA 2C8CA 2GWLA 1PWWA 2J3VA 1R45A 5H04A 2WN6A 4PKWA 2C8HA 4FXQA 4XSHB 2A9KB 4PKRA 1GIRA 4H03A 1GXZA 1QS2A 4DV8A 1J7NA 4H0VA 5D1SA 2WN5A 4XSGB 4ELNA 1UZIA 3NTSA 1OG4A 4GY2A 1OJQA 4H0YA 2C8GA 4H0XA 2C8DA 5D1TA 1GXYA 4FK7A 2C8AA 1PWVA 4H0TA 1PWQA 1PWUA 4TR5A 1OG3A 2C8FE 4FMLA 5H03A 1R4BA 3BUZA 2GWMA 4PKVA 5D1UA 3U0JA 4PKUA 1PWPA 3BW8A 4GF1A 1GIQA 2C8EE 4XM6A 2C89A 1JKYA 1QS1A 1G24A
chains in the Genus database with same CATH superfamily
1GZEA 1OJZA 4XM7A 1GY0A 1OG1A 1ZXVA 4XM8A 4PKTA 2BOVB 1YQYA 2WN7A 5GTTA 2WN4A 1GZFA 5BWMB 2J3XA 5DZQA 2J3ZA 2C8BX 4WF6A 2A78B 4PKQA 2WN8A 4PKSA 2C8CA 2GWLA 1PWWA 2J3VA 1R45A 5H04A 2WN6A 4PKWA 2C8HA 4FXQA 4XSHB 2A9KB 4PKRA 1GIRA 4H03A 1GXZA 1QS2A 4DV8A 1J7NA 4H0VA 5D1SA 2WN5A 4XSGB 4ELNA 1UZIA 3NTSA 1OG4A 4GY2A 1OJQA 4H0YA 2C8GA 4H0XA 2C8DA 5D1TA 1GXYA 4FK7A 2C8AA 1PWVA 4H0TA 1PWQA 1PWUA 4TR5A 1OG3A 2C8FE 4FMLA 5H03A 1R4BA 3BUZA 2GWMA 4PKVA 5D1UA 3U0JA 4PKUA 1PWPA 3BW8A 4GF1A 1GIQA 2C8EE 4XM6A 2C89A 1JKYA 1QS1A 1G24A
chains in the Genus database with same CATH topology
1GZEA 1OJZA 4XM7A 1GY0A 1OG1A 1ZXVA 4XM8A 4PKTA 2BOVB 1YQYA 2WN7A 5GTTA 2WN4A 1GZFA 5BWMB 2J3XA 5DZQA 2J3ZA 2C8BX 4WF6A 2A78B 4PKQA 2WN8A 4PKSA 2C8CA 2GWLA 1PWWA 2J3VA 1R45A 5H04A 2WN6A 4PKWA 2C8HA 4FXQA 4XSHB 2A9KB 4PKRA 1GIRA 4H03A 1GXZA 1QS2A 4DV8A 1J7NA 4H0VA 5D1SA 2WN5A 4XSGB 4ELNA 1UZIA 3NTSA 1OG4A 4GY2A 1OJQA 4H0YA 2C8GA 4H0XA 2C8DA 5D1TA 1GXYA 4FK7A 2C8AA 1PWVA 4H0TA 1PWQA 1PWUA 4TR5A 1OG3A 2C8FE 4FMLA 5H03A 1R4BA 3BUZA 2GWMA 4PKVA 5D1UA 3U0JA 4PKUA 1PWPA 3BW8A 4GF1A 1GIQA 2C8EE 4XM6A 2C89A 1JKYA 1QS1A 1G24A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GZE A;  1OJZ A;  4XM7 A;  1GY0 A;  1OG1 A;  1ZXV A;  4XM8 A;  4PKT A;  2BOV B;  1YQY A;  2WN7 A;  5GTT A;  2WN4 A;  1GZF A;  5BWM B;  2J3X A;  5DZQ A;  2J3Z A;  2C8B X;  4WF6 A;  2A78 B;  4PKQ A;  2WN8 A;  4PKS A;  2C8C A;  2GWL A;  1PWW A;  2J3V A;  1R45 A;  5H04 A;  2WN6 A;  4PKW A;  2C8H A;  4FXQ A;  4XSH B;  2A9K B;  4PKR A;  1GIR A;  4H03 A;  1GXZ A;  1QS2 A;  4DV8 A;  1J7N A;  4H0V A;  5D1S A;  2WN5 A;  4XSG B;  4ELN A;  1UZI A;  3NTS A;  1OG4 A;  4GY2 A;  1OJQ A;  4H0Y A;  2C8G A;  4H0X A;  2C8D A;  5D1T A;  1GXY A;  4FK7 A;  2C8A A;  1PWV A;  4H0T A;  1PWQ A;  1PWU A;  4TR5 A;  1OG3 A;  2C8F E;  4FML A;  5H03 A;  1R4B A;  3BUZ A;  2GWM A;  4PKV A;  5D1U A;  3U0J A;  4PKU A;  1PWP A;  3BW8 A;  4GF1 A;  1GIQ A;  2C8E E;  4XM6 A;  2C89 A;  1JKY A;  1QS1 A;  1G24 A; 
#chains in the Genus database with same CATH topology
 1GZE A;  1OJZ A;  4XM7 A;  1GY0 A;  1OG1 A;  1ZXV A;  4XM8 A;  4PKT A;  2BOV B;  1YQY A;  2WN7 A;  5GTT A;  2WN4 A;  1GZF A;  5BWM B;  2J3X A;  5DZQ A;  2J3Z A;  2C8B X;  4WF6 A;  2A78 B;  4PKQ A;  2WN8 A;  4PKS A;  2C8C A;  2GWL A;  1PWW A;  2J3V A;  1R45 A;  5H04 A;  2WN6 A;  4PKW A;  2C8H A;  4FXQ A;  4XSH B;  2A9K B;  4PKR A;  1GIR A;  4H03 A;  1GXZ A;  1QS2 A;  4DV8 A;  1J7N A;  4H0V A;  5D1S A;  2WN5 A;  4XSG B;  4ELN A;  1UZI A;  3NTS A;  1OG4 A;  4GY2 A;  1OJQ A;  4H0Y A;  2C8G A;  4H0X A;  2C8D A;  5D1T A;  1GXY A;  4FK7 A;  2C8A A;  1PWV A;  4H0T A;  1PWQ A;  1PWU A;  4TR5 A;  1OG3 A;  2C8F E;  4FML A;  5H03 A;  1R4B A;  3BUZ A;  2GWM A;  4PKV A;  5D1U A;  3U0J A;  4PKU A;  1PWP A;  3BW8 A;  4GF1 A;  1GIQ A;  2C8E E;  4XM6 A;  2C89 A;  1JKY A;  1QS1 A;  1G24 A; 
#chains in the Genus database with same CATH homology
 1GZE A;  1OJZ A;  4XM7 A;  1GY0 A;  1OG1 A;  1ZXV A;  4XM8 A;  4PKT A;  2BOV B;  1YQY A;  2WN7 A;  5GTT A;  2WN4 A;  1GZF A;  5BWM B;  2J3X A;  5DZQ A;  2J3Z A;  2C8B X;  4WF6 A;  2A78 B;  4PKQ A;  2WN8 A;  4PKS A;  2C8C A;  2GWL A;  1PWW A;  2J3V A;  1R45 A;  5H04 A;  2WN6 A;  4PKW A;  2C8H A;  4FXQ A;  4XSH B;  2A9K B;  4PKR A;  1GIR A;  4H03 A;  1GXZ A;  1QS2 A;  4DV8 A;  1J7N A;  4H0V A;  5D1S A;  2WN5 A;  4XSG B;  4ELN A;  1UZI A;  3NTS A;  1OG4 A;  4GY2 A;  1OJQ A;  4H0Y A;  2C8G A;  4H0X A;  2C8D A;  5D1T A;  1GXY A;  4FK7 A;  2C8A A;  1PWV A;  4H0T A;  1PWQ A;  1PWU A;  4TR5 A;  1OG3 A;  2C8F E;  4FML A;  5H03 A;  1R4B A;  3BUZ A;  2GWM A;  4PKV A;  5D1U A;  3U0J A;  4PKU A;  1PWP A;  3BW8 A;  4GF1 A;  1GIQ A;  2C8E E;  4XM6 A;  2C89 A;  1JKY A;  1QS1 A;  1G24 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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