4GY2A

Crystal structure of apo-ia-actin complex
Total Genus 137
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
137
sequence length
411
structure length
411
Chain Sequence
IERPEDFLKDKENAIQWEKKEAERVEKNLDTLEKEALELYKKDSEQISNYSQTRQYFYDYQIESNPREKEYKNLRNAISKNKIDKPINVYYFESPEKFAFNKEIRTENQNEISLEKFNELKETIQDKLFKQDGFKDVSLYEPGNGDEKPTPLLIHLKLPKNTGMLPYINSNDVKTLIEQDYSIKIDKIVRIVIEGKQYIKAEASIVNSLDFKDDVSKGDLWGKENYSDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPLNNPNPELDSKVNNIENALKLTPIPSNLIVYRRSGPQEFGLTLTSPEYDFNKIENIDAFKEKWEGKVITYPNFISTSIGSVNMSAFAKRKIILRINIPKDSPGAYLSAIPGYAGEYEVLLNHGSKFKINKVDSYKDGTVTKLILDATLIN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Iota toxin component Ia
publication title Arginine ADP-ribosylation mechanism based on structural snapshots of iota-toxin and actin complex
pubmed doi rcsb
source organism Clostridium perfringens
molecule tags Toxin/structural protein
total genus 137
structure length 411
sequence length 411
ec nomenclature ec 2.4.2.31: NAD(+)--protein-arginine ADP-ribosyltransferase.
pdb deposition date 2012-09-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4gy2A02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4gy2A01
4GF1A 1PWPA 5BWMB 1J7NA 1OJQA 4XM7A 4ELNA 4XM6A 2GWMA 1JKYA 1PWVA 1YQYA 1GIQA 1GIRA 2BOVB 2C8AA 2WN7A 3NTSA 2C8BX 1GXZA 4H03A 5D1SA 5H04A 1GXYA 1OG3A 2C8CA 4H0TA 1OG4A 4FK7A 4PKSA 2A9KB 4FXQA 4GY2A 1PWQA 2J3VA 1R4BA 2WN6A 1OG1A 2WN5A 1GY0A 2GWLA 4PKVA 5GTTA 2C8EE 1G24A 5D1TA 3U0JA 2J3ZA 2A78B 2C8HA 5D1UA 4XSGB 4PKWA 4PKQA 5DZQA 1PWUA 1QS1A 2C89A 1UZIA 4TR5A 2J3XA 3BW8A 5H03A 3BUZA 2WN4A 4XSHB 1OJZA 1GZFA 4H0YA 4XM8A 1PWWA 4H0XA 1ZXVA 2C8FE 2C8GA 4DV8A 4H0VA 4WF6A 4PKTA 1R45A 2C8DA 1GZEA 4FMLA 4PKUA 4PKRA 2WN8A 1QS2A
chains in the Genus database with same CATH superfamily
4GF1A 1PWPA 5BWMB 1J7NA 1OJQA 4XM7A 4ELNA 4XM6A 2GWMA 1JKYA 1PWVA 1YQYA 1GIQA 1GIRA 2BOVB 2C8AA 2WN7A 3NTSA 2C8BX 1GXZA 4H03A 5D1SA 5H04A 1GXYA 1OG3A 2C8CA 4H0TA 1OG4A 4FK7A 4PKSA 2A9KB 4FXQA 4GY2A 1PWQA 2J3VA 1R4BA 2WN6A 1OG1A 2WN5A 1GY0A 2GWLA 4PKVA 5GTTA 2C8EE 1G24A 5D1TA 3U0JA 2J3ZA 2A78B 2C8HA 5D1UA 4XSGB 4PKWA 4PKQA 5DZQA 1PWUA 1QS1A 2C89A 1UZIA 4TR5A 2J3XA 3BW8A 5H03A 3BUZA 2WN4A 4XSHB 1OJZA 1GZFA 4H0YA 4XM8A 1PWWA 4H0XA 1ZXVA 2C8FE 2C8GA 4DV8A 4H0VA 4WF6A 4PKTA 1R45A 2C8DA 1GZEA 4FMLA 4PKUA 4PKRA 2WN8A 1QS2A
chains in the Genus database with same CATH topology
4GF1A 1PWPA 5BWMB 1J7NA 1OJQA 4XM7A 4ELNA 4XM6A 2GWMA 1JKYA 1PWVA 1YQYA 1GIQA 1GIRA 2BOVB 2C8AA 2WN7A 3NTSA 2C8BX 1GXZA 4H03A 5D1SA 5H04A 1GXYA 1OG3A 2C8CA 4H0TA 1OG4A 4FK7A 4PKSA 2A9KB 4FXQA 4GY2A 1PWQA 2J3VA 1R4BA 2WN6A 1OG1A 2WN5A 1GY0A 2GWLA 4PKVA 5GTTA 2C8EE 1G24A 5D1TA 3U0JA 2J3ZA 2A78B 2C8HA 5D1UA 4XSGB 4PKWA 4PKQA 5DZQA 1PWUA 1QS1A 2C89A 1UZIA 4TR5A 2J3XA 3BW8A 5H03A 3BUZA 2WN4A 4XSHB 1OJZA 1GZFA 4H0YA 4XM8A 1PWWA 4H0XA 1ZXVA 2C8FE 2C8GA 4DV8A 4H0VA 4WF6A 4PKTA 1R45A 2C8DA 1GZEA 4FMLA 4PKUA 4PKRA 2WN8A 1QS2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GF1 A;  1PWP A;  5BWM B;  1J7N A;  1OJQ A;  4XM7 A;  4ELN A;  4XM6 A;  2GWM A;  1JKY A;  1PWV A;  1YQY A;  1GIQ A;  1GIR A;  2BOV B;  2C8A A;  2WN7 A;  3NTS A;  2C8B X;  1GXZ A;  4H03 A;  5D1S A;  5H04 A;  1GXY A;  1OG3 A;  2C8C A;  4H0T A;  1OG4 A;  4FK7 A;  4PKS A;  2A9K B;  4FXQ A;  4GY2 A;  1PWQ A;  2J3V A;  1R4B A;  2WN6 A;  1OG1 A;  2WN5 A;  1GY0 A;  2GWL A;  4PKV A;  5GTT A;  2C8E E;  1G24 A;  5D1T A;  3U0J A;  2J3Z A;  2A78 B;  2C8H A;  5D1U A;  4XSG B;  4PKW A;  4PKQ A;  5DZQ A;  1PWU A;  1QS1 A;  2C89 A;  1UZI A;  4TR5 A;  2J3X A;  3BW8 A;  5H03 A;  3BUZ A;  2WN4 A;  4XSH B;  1OJZ A;  1GZF A;  4H0Y A;  4XM8 A;  1PWW A;  4H0X A;  1ZXV A;  2C8F E;  2C8G A;  4DV8 A;  4H0V A;  4WF6 A;  4PKT A;  1R45 A;  2C8D A;  1GZE A;  4FML A;  4PKU A;  4PKR A;  2WN8 A;  1QS2 A; 
#chains in the Genus database with same CATH topology
 4GF1 A;  1PWP A;  5BWM B;  1J7N A;  1OJQ A;  4XM7 A;  4ELN A;  4XM6 A;  2GWM A;  1JKY A;  1PWV A;  1YQY A;  1GIQ A;  1GIR A;  2BOV B;  2C8A A;  2WN7 A;  3NTS A;  2C8B X;  1GXZ A;  4H03 A;  5D1S A;  5H04 A;  1GXY A;  1OG3 A;  2C8C A;  4H0T A;  1OG4 A;  4FK7 A;  4PKS A;  2A9K B;  4FXQ A;  4GY2 A;  1PWQ A;  2J3V A;  1R4B A;  2WN6 A;  1OG1 A;  2WN5 A;  1GY0 A;  2GWL A;  4PKV A;  5GTT A;  2C8E E;  1G24 A;  5D1T A;  3U0J A;  2J3Z A;  2A78 B;  2C8H A;  5D1U A;  4XSG B;  4PKW A;  4PKQ A;  5DZQ A;  1PWU A;  1QS1 A;  2C89 A;  1UZI A;  4TR5 A;  2J3X A;  3BW8 A;  5H03 A;  3BUZ A;  2WN4 A;  4XSH B;  1OJZ A;  1GZF A;  4H0Y A;  4XM8 A;  1PWW A;  4H0X A;  1ZXV A;  2C8F E;  2C8G A;  4DV8 A;  4H0V A;  4WF6 A;  4PKT A;  1R45 A;  2C8D A;  1GZE A;  4FML A;  4PKU A;  4PKR A;  2WN8 A;  1QS2 A; 
#chains in the Genus database with same CATH homology
 4GF1 A;  1PWP A;  5BWM B;  1J7N A;  1OJQ A;  4XM7 A;  4ELN A;  4XM6 A;  2GWM A;  1JKY A;  1PWV A;  1YQY A;  1GIQ A;  1GIR A;  2BOV B;  2C8A A;  2WN7 A;  3NTS A;  2C8B X;  1GXZ A;  4H03 A;  5D1S A;  5H04 A;  1GXY A;  1OG3 A;  2C8C A;  4H0T A;  1OG4 A;  4FK7 A;  4PKS A;  2A9K B;  4FXQ A;  4GY2 A;  1PWQ A;  2J3V A;  1R4B A;  2WN6 A;  1OG1 A;  2WN5 A;  1GY0 A;  2GWL A;  4PKV A;  5GTT A;  2C8E E;  1G24 A;  5D1T A;  3U0J A;  2J3Z A;  2A78 B;  2C8H A;  5D1U A;  4XSG B;  4PKW A;  4PKQ A;  5DZQ A;  1PWU A;  1QS1 A;  2C89 A;  1UZI A;  4TR5 A;  2J3X A;  3BW8 A;  5H03 A;  3BUZ A;  2WN4 A;  4XSH B;  1OJZ A;  1GZF A;  4H0Y A;  4XM8 A;  1PWW A;  4H0X A;  1ZXV A;  2C8F E;  2C8G A;  4DV8 A;  4H0V A;  4WF6 A;  4PKT A;  1R45 A;  2C8D A;  1GZE A;  4FML A;  4PKU A;  4PKR A;  2WN8 A;  1QS2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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