4H0YA

Crystal structure of nad+-ia(e380s)-actin complex
Total Genus 143
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
143
sequence length
413
structure length
413
Chain Sequence
AFIERPEDFLKDKENAIQWEKKEAERVEKNLDTLEKEALELYKKDSEQISNYSQTRQYFYDYQIESNPREKEYKNLRNAISKNKIDKPINVYYFESPEKFAFNKEIRTENQNEISLEKFNELKETIQDKLFKQDGFKDVSLYEPGNGDEKPTPLLIHLKLPKNTGMLPYINSNDVKTLIEQDYSIKIDKIVRIVIEGKQYIKAEASIVNSLDFKDDVSKGDLWGKENYSDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPLNNPNPELDSKVNNIENALKLTPIPSNLIVYRRSGPQEFGLTLTSPEYDFNKIENIDAFKEKWEGKVITYPNFISTSIGSVNMSAFAKRKIILRINIPKDSPGAYLSAIPGYAGEYSVLLNHGSKFKINKVDSYKDGTVTKLILDATLIN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Iota toxin component Ia
publication title Arginine ADP-ribosylation mechanism based on structural snapshots of iota-toxin and actin complex
pubmed doi rcsb
source organism Clostridium perfringens
molecule tags Toxin/structural protein
total genus 143
structure length 413
sequence length 413
ec nomenclature ec 2.4.2.31: NAD(+)--protein-arginine ADP-ribosyltransferase.
pdb deposition date 2012-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4h0yA02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4h0yA01
2WN5A 3U0JA 2A9KB 2C8BX 5H03A 1OG1A 4XM6A 4FMLA 2C8FE 2C8EE 1GZFA 3NTSA 2J3VA 4PKQA 1QS2A 1ZXVA 4ELNA 5BWMB 2WN8A 1GZEA 5D1UA 4H0XA 2C8DA 1PWUA 1OJZA 1YQYA 2GWLA 4TR5A 4XM7A 4PKWA 2GWMA 4DV8A 2J3ZA 2WN6A 1GIQA 1PWQA 1QS1A 2C8GA 1PWVA 3BW8A 2BOVB 4H0YA 4PKUA 4GF1A 2C8CA 1PWPA 1OG3A 1R4BA 4GY2A 2A78B 4PKVA 1JKYA 3BUZA 1PWWA 1GIRA 5H04A 1GXYA 4PKSA 1UZIA 4PKTA 2WN7A 4XSHB 1J7NA 1GXZA 4XSGB 1GY0A 5GTTA 1G24A 5D1TA 1R45A 2C8HA 4XM8A 4H03A 4FK7A 2C89A 1OG4A 2J3XA 4WF6A 2WN4A 4H0VA 4FXQA 2C8AA 5DZQA 4H0TA 4PKRA 5D1SA 1OJQA
chains in the Genus database with same CATH superfamily
2WN5A 3U0JA 2A9KB 2C8BX 5H03A 1OG1A 4XM6A 4FMLA 2C8FE 2C8EE 1GZFA 3NTSA 2J3VA 4PKQA 1QS2A 1ZXVA 4ELNA 5BWMB 2WN8A 1GZEA 5D1UA 4H0XA 2C8DA 1PWUA 1OJZA 1YQYA 2GWLA 4TR5A 4XM7A 4PKWA 2GWMA 4DV8A 2J3ZA 2WN6A 1GIQA 1PWQA 1QS1A 2C8GA 1PWVA 3BW8A 2BOVB 4H0YA 4PKUA 4GF1A 2C8CA 1PWPA 1OG3A 1R4BA 4GY2A 2A78B 4PKVA 1JKYA 3BUZA 1PWWA 1GIRA 5H04A 1GXYA 4PKSA 1UZIA 4PKTA 2WN7A 4XSHB 1J7NA 1GXZA 4XSGB 1GY0A 5GTTA 1G24A 5D1TA 1R45A 2C8HA 4XM8A 4H03A 4FK7A 2C89A 1OG4A 2J3XA 4WF6A 2WN4A 4H0VA 4FXQA 2C8AA 5DZQA 4H0TA 4PKRA 5D1SA 1OJQA
chains in the Genus database with same CATH topology
2WN5A 3U0JA 2A9KB 2C8BX 5H03A 1OG1A 4XM6A 4FMLA 2C8FE 2C8EE 1GZFA 3NTSA 2J3VA 4PKQA 1QS2A 1ZXVA 4ELNA 5BWMB 2WN8A 1GZEA 5D1UA 4H0XA 2C8DA 1PWUA 1OJZA 1YQYA 2GWLA 4TR5A 4XM7A 4PKWA 2GWMA 4DV8A 2J3ZA 2WN6A 1GIQA 1PWQA 1QS1A 2C8GA 1PWVA 3BW8A 2BOVB 4H0YA 4PKUA 4GF1A 2C8CA 1PWPA 1OG3A 1R4BA 4GY2A 2A78B 4PKVA 1JKYA 3BUZA 1PWWA 1GIRA 5H04A 1GXYA 4PKSA 1UZIA 4PKTA 2WN7A 4XSHB 1J7NA 1GXZA 4XSGB 1GY0A 5GTTA 1G24A 5D1TA 1R45A 2C8HA 4XM8A 4H03A 4FK7A 2C89A 1OG4A 2J3XA 4WF6A 2WN4A 4H0VA 4FXQA 2C8AA 5DZQA 4H0TA 4PKRA 5D1SA 1OJQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WN5 A;  3U0J A;  2A9K B;  2C8B X;  5H03 A;  1OG1 A;  4XM6 A;  4FML A;  2C8F E;  2C8E E;  1GZF A;  3NTS A;  2J3V A;  4PKQ A;  1QS2 A;  1ZXV A;  4ELN A;  5BWM B;  2WN8 A;  1GZE A;  5D1U A;  4H0X A;  2C8D A;  1PWU A;  1OJZ A;  1YQY A;  2GWL A;  4TR5 A;  4XM7 A;  4PKW A;  2GWM A;  4DV8 A;  2J3Z A;  2WN6 A;  1GIQ A;  1PWQ A;  1QS1 A;  2C8G A;  1PWV A;  3BW8 A;  2BOV B;  4H0Y A;  4PKU A;  4GF1 A;  2C8C A;  1PWP A;  1OG3 A;  1R4B A;  4GY2 A;  2A78 B;  4PKV A;  1JKY A;  3BUZ A;  1PWW A;  1GIR A;  5H04 A;  1GXY A;  4PKS A;  1UZI A;  4PKT A;  2WN7 A;  4XSH B;  1J7N A;  1GXZ A;  4XSG B;  1GY0 A;  5GTT A;  1G24 A;  5D1T A;  1R45 A;  2C8H A;  4XM8 A;  4H03 A;  4FK7 A;  2C89 A;  1OG4 A;  2J3X A;  4WF6 A;  2WN4 A;  4H0V A;  4FXQ A;  2C8A A;  5DZQ A;  4H0T A;  4PKR A;  5D1S A;  1OJQ A; 
#chains in the Genus database with same CATH topology
 2WN5 A;  3U0J A;  2A9K B;  2C8B X;  5H03 A;  1OG1 A;  4XM6 A;  4FML A;  2C8F E;  2C8E E;  1GZF A;  3NTS A;  2J3V A;  4PKQ A;  1QS2 A;  1ZXV A;  4ELN A;  5BWM B;  2WN8 A;  1GZE A;  5D1U A;  4H0X A;  2C8D A;  1PWU A;  1OJZ A;  1YQY A;  2GWL A;  4TR5 A;  4XM7 A;  4PKW A;  2GWM A;  4DV8 A;  2J3Z A;  2WN6 A;  1GIQ A;  1PWQ A;  1QS1 A;  2C8G A;  1PWV A;  3BW8 A;  2BOV B;  4H0Y A;  4PKU A;  4GF1 A;  2C8C A;  1PWP A;  1OG3 A;  1R4B A;  4GY2 A;  2A78 B;  4PKV A;  1JKY A;  3BUZ A;  1PWW A;  1GIR A;  5H04 A;  1GXY A;  4PKS A;  1UZI A;  4PKT A;  2WN7 A;  4XSH B;  1J7N A;  1GXZ A;  4XSG B;  1GY0 A;  5GTT A;  1G24 A;  5D1T A;  1R45 A;  2C8H A;  4XM8 A;  4H03 A;  4FK7 A;  2C89 A;  1OG4 A;  2J3X A;  4WF6 A;  2WN4 A;  4H0V A;  4FXQ A;  2C8A A;  5DZQ A;  4H0T A;  4PKR A;  5D1S A;  1OJQ A; 
#chains in the Genus database with same CATH homology
 2WN5 A;  3U0J A;  2A9K B;  2C8B X;  5H03 A;  1OG1 A;  4XM6 A;  4FML A;  2C8F E;  2C8E E;  1GZF A;  3NTS A;  2J3V A;  4PKQ A;  1QS2 A;  1ZXV A;  4ELN A;  5BWM B;  2WN8 A;  1GZE A;  5D1U A;  4H0X A;  2C8D A;  1PWU A;  1OJZ A;  1YQY A;  2GWL A;  4TR5 A;  4XM7 A;  4PKW A;  2GWM A;  4DV8 A;  2J3Z A;  2WN6 A;  1GIQ A;  1PWQ A;  1QS1 A;  2C8G A;  1PWV A;  3BW8 A;  2BOV B;  4H0Y A;  4PKU A;  4GF1 A;  2C8C A;  1PWP A;  1OG3 A;  1R4B A;  4GY2 A;  2A78 B;  4PKV A;  1JKY A;  3BUZ A;  1PWW A;  1GIR A;  5H04 A;  1GXY A;  4PKS A;  1UZI A;  4PKT A;  2WN7 A;  4XSH B;  1J7N A;  1GXZ A;  4XSG B;  1GY0 A;  5GTT A;  1G24 A;  5D1T A;  1R45 A;  2C8H A;  4XM8 A;  4H03 A;  4FK7 A;  2C89 A;  1OG4 A;  2J3X A;  4WF6 A;  2WN4 A;  4H0V A;  4FXQ A;  2C8A A;  5DZQ A;  4H0T A;  4PKR A;  5D1S A;  1OJQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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