4H0YA

Crystal structure of nad+-ia(e380s)-actin complex
Total Genus 143
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
143
sequence length
413
structure length
413
Chain Sequence
AFIERPEDFLKDKENAIQWEKKEAERVEKNLDTLEKEALELYKKDSEQISNYSQTRQYFYDYQIESNPREKEYKNLRNAISKNKIDKPINVYYFESPEKFAFNKEIRTENQNEISLEKFNELKETIQDKLFKQDGFKDVSLYEPGNGDEKPTPLLIHLKLPKNTGMLPYINSNDVKTLIEQDYSIKIDKIVRIVIEGKQYIKAEASIVNSLDFKDDVSKGDLWGKENYSDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPLNNPNPELDSKVNNIENALKLTPIPSNLIVYRRSGPQEFGLTLTSPEYDFNKIENIDAFKEKWEGKVITYPNFISTSIGSVNMSAFAKRKIILRINIPKDSPGAYLSAIPGYAGEYSVLLNHGSKFKINKVDSYKDGTVTKLILDATLIN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin/structural protein
molecule keywords Iota toxin component Ia
publication title Arginine ADP-ribosylation mechanism based on structural snapshots of iota-toxin and actin complex
pubmed doi rcsb
source organism Clostridium perfringens
total genus 143
structure length 413
sequence length 413
ec nomenclature ec 2.4.2.31: NAD(+)--protein-arginine ADP-ribosyltransferase.
pdb deposition date 2012-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4h0yA02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4h0yA01
1QS2A 1GY0A 1PWQA 1YQYA 2WN5A 1OG4A 2J3ZA 1QS1A 3BUZA 4H03A 2GWMA 2WN8A 4XM8A 2C8DA 1GXZA 1J7NA 5H03A 4H0VA 4PKRA 4FXQA 4GF1A 4GY2A 5D1TA 1UZIA 2C8BX 5H04A 2C8GA 1ZXVA 4XM6A 4FK7A 4TR5A 2BOVB 1GZFA 1GIQA 4PKUA 5GTTA 2C8HA 1GXYA 4H0TA 4PKVA 2A78B 2C8AA 4PKWA 2WN6A 3BW8A 1G24A 1GIRA 4WF6A 2GWLA 2C8CA 2A9KB 4XM7A 5D1SA 1JKYA 1OG1A 2WN4A 1PWUA 4H0XA 4XSHB 1OJQA 4H0YA 1OJZA 4PKTA 2C8FE 2C89A 4XSGB 1GZEA 4PKQA 1PWPA 4DV8A 1R45A 4PKSA 4FMLA 1PWWA 1R4BA 5D1UA 2WN7A 5BWMB 3NTSA 1PWVA 5DZQA 2J3XA 1OG3A 3U0JA 4ELNA 2C8EE 2J3VA
chains in the Genus database with same CATH superfamily
1QS2A 1GY0A 1PWQA 1YQYA 2WN5A 1OG4A 2J3ZA 1QS1A 3BUZA 4H03A 2GWMA 2WN8A 4XM8A 2C8DA 1GXZA 1J7NA 5H03A 4H0VA 4PKRA 4FXQA 4GF1A 4GY2A 5D1TA 1UZIA 2C8BX 5H04A 2C8GA 1ZXVA 4XM6A 4FK7A 4TR5A 2BOVB 1GZFA 1GIQA 4PKUA 5GTTA 2C8HA 1GXYA 4H0TA 4PKVA 2A78B 2C8AA 4PKWA 2WN6A 3BW8A 1G24A 1GIRA 4WF6A 2GWLA 2C8CA 2A9KB 4XM7A 5D1SA 1JKYA 1OG1A 2WN4A 1PWUA 4H0XA 4XSHB 1OJQA 4H0YA 1OJZA 4PKTA 2C8FE 2C89A 4XSGB 1GZEA 4PKQA 1PWPA 4DV8A 1R45A 4PKSA 4FMLA 1PWWA 1R4BA 5D1UA 2WN7A 5BWMB 3NTSA 1PWVA 5DZQA 2J3XA 1OG3A 3U0JA 4ELNA 2C8EE 2J3VA
chains in the Genus database with same CATH topology
1QS2A 1GY0A 1PWQA 1YQYA 2WN5A 1OG4A 2J3ZA 1QS1A 3BUZA 4H03A 2GWMA 2WN8A 4XM8A 2C8DA 1GXZA 1J7NA 5H03A 4H0VA 4PKRA 4FXQA 4GF1A 4GY2A 5D1TA 1UZIA 2C8BX 5H04A 2C8GA 1ZXVA 4XM6A 4FK7A 4TR5A 2BOVB 1GZFA 1GIQA 4PKUA 5GTTA 2C8HA 1GXYA 4H0TA 4PKVA 2A78B 2C8AA 4PKWA 2WN6A 3BW8A 1G24A 1GIRA 4WF6A 2GWLA 2C8CA 2A9KB 4XM7A 5D1SA 1JKYA 1OG1A 2WN4A 1PWUA 4H0XA 4XSHB 1OJQA 4H0YA 1OJZA 4PKTA 2C8FE 2C89A 4XSGB 1GZEA 4PKQA 1PWPA 4DV8A 1R45A 4PKSA 4FMLA 1PWWA 1R4BA 5D1UA 2WN7A 5BWMB 3NTSA 1PWVA 5DZQA 2J3XA 1OG3A 3U0JA 4ELNA 2C8EE 2J3VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QS2 A;  1GY0 A;  1PWQ A;  1YQY A;  2WN5 A;  1OG4 A;  2J3Z A;  1QS1 A;  3BUZ A;  4H03 A;  2GWM A;  2WN8 A;  4XM8 A;  2C8D A;  1GXZ A;  1J7N A;  5H03 A;  4H0V A;  4PKR A;  4FXQ A;  4GF1 A;  4GY2 A;  5D1T A;  1UZI A;  2C8B X;  5H04 A;  2C8G A;  1ZXV A;  4XM6 A;  4FK7 A;  4TR5 A;  2BOV B;  1GZF A;  1GIQ A;  4PKU A;  5GTT A;  2C8H A;  1GXY A;  4H0T A;  4PKV A;  2A78 B;  2C8A A;  4PKW A;  2WN6 A;  3BW8 A;  1G24 A;  1GIR A;  4WF6 A;  2GWL A;  2C8C A;  2A9K B;  4XM7 A;  5D1S A;  1JKY A;  1OG1 A;  2WN4 A;  1PWU A;  4H0X A;  4XSH B;  1OJQ A;  4H0Y A;  1OJZ A;  4PKT A;  2C8F E;  2C89 A;  4XSG B;  1GZE A;  4PKQ A;  1PWP A;  4DV8 A;  1R45 A;  4PKS A;  4FML A;  1PWW A;  1R4B A;  5D1U A;  2WN7 A;  5BWM B;  3NTS A;  1PWV A;  5DZQ A;  2J3X A;  1OG3 A;  3U0J A;  4ELN A;  2C8E E;  2J3V A; 
#chains in the Genus database with same CATH topology
 1QS2 A;  1GY0 A;  1PWQ A;  1YQY A;  2WN5 A;  1OG4 A;  2J3Z A;  1QS1 A;  3BUZ A;  4H03 A;  2GWM A;  2WN8 A;  4XM8 A;  2C8D A;  1GXZ A;  1J7N A;  5H03 A;  4H0V A;  4PKR A;  4FXQ A;  4GF1 A;  4GY2 A;  5D1T A;  1UZI A;  2C8B X;  5H04 A;  2C8G A;  1ZXV A;  4XM6 A;  4FK7 A;  4TR5 A;  2BOV B;  1GZF A;  1GIQ A;  4PKU A;  5GTT A;  2C8H A;  1GXY A;  4H0T A;  4PKV A;  2A78 B;  2C8A A;  4PKW A;  2WN6 A;  3BW8 A;  1G24 A;  1GIR A;  4WF6 A;  2GWL A;  2C8C A;  2A9K B;  4XM7 A;  5D1S A;  1JKY A;  1OG1 A;  2WN4 A;  1PWU A;  4H0X A;  4XSH B;  1OJQ A;  4H0Y A;  1OJZ A;  4PKT A;  2C8F E;  2C89 A;  4XSG B;  1GZE A;  4PKQ A;  1PWP A;  4DV8 A;  1R45 A;  4PKS A;  4FML A;  1PWW A;  1R4B A;  5D1U A;  2WN7 A;  5BWM B;  3NTS A;  1PWV A;  5DZQ A;  2J3X A;  1OG3 A;  3U0J A;  4ELN A;  2C8E E;  2J3V A; 
#chains in the Genus database with same CATH homology
 1QS2 A;  1GY0 A;  1PWQ A;  1YQY A;  2WN5 A;  1OG4 A;  2J3Z A;  1QS1 A;  3BUZ A;  4H03 A;  2GWM A;  2WN8 A;  4XM8 A;  2C8D A;  1GXZ A;  1J7N A;  5H03 A;  4H0V A;  4PKR A;  4FXQ A;  4GF1 A;  4GY2 A;  5D1T A;  1UZI A;  2C8B X;  5H04 A;  2C8G A;  1ZXV A;  4XM6 A;  4FK7 A;  4TR5 A;  2BOV B;  1GZF A;  1GIQ A;  4PKU A;  5GTT A;  2C8H A;  1GXY A;  4H0T A;  4PKV A;  2A78 B;  2C8A A;  4PKW A;  2WN6 A;  3BW8 A;  1G24 A;  1GIR A;  4WF6 A;  2GWL A;  2C8C A;  2A9K B;  4XM7 A;  5D1S A;  1JKY A;  1OG1 A;  2WN4 A;  1PWU A;  4H0X A;  4XSH B;  1OJQ A;  4H0Y A;  1OJZ A;  4PKT A;  2C8F E;  2C89 A;  4XSG B;  1GZE A;  4PKQ A;  1PWP A;  4DV8 A;  1R45 A;  4PKS A;  4FML A;  1PWW A;  1R4B A;  5D1U A;  2WN7 A;  5BWM B;  3NTS A;  1PWV A;  5DZQ A;  2J3X A;  1OG3 A;  3U0J A;  4ELN A;  2C8E E;  2J3V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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