2WN7A

Structural basis for substrate recognition in the enzymatic component of adp-ribosyltransferase toxin cdta from clostridium difficile
Total Genus 132
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
132
sequence length
394
structure length
392
Chain Sequence
ERKEAERIEQKLERSEKEALESYKKDSVEISKYSQTRNYFYDYQIEANSREKEYKELRNAISKNKIDKPMYVYYFESPEKFAFNKVIRTENQNEISLEKFNEFKETIQNKLFKQDGFKDISLYEPGKGDEKPTPLLMHLKLPRNTGMLPYTNNVSTLIEQGYSIKIDKIVRIVIDGKHYIKAEASVVSSLDFKDDVSKGDSWGKANYNDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPVNNPNPELDSKITNIENALKREPIPTNLTVYRRSGPQEFGLTLTSPEYDFNKLENIDAFKSKWEGQALSYPNFISTSIGSVNMSAFAKRKIVLRITIPKGSPGAYLSAIPGYAGEYEVLLNHGSKFKINKIDSYKDGTITKLIVDATLIP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords ADP-RIBOSYLTRANSFERASE ENZYMATIC COMPONENT
publication title Structural Basis for Substrate Recognition in the Enzymatic Component of Adp-Ribosyltransferase Toxin Cdta from Clostridium Difficile.
pubmed doi rcsb
source organism Clostridium difficile
total genus 132
structure length 392
sequence length 394
ec nomenclature
pdb deposition date 2009-07-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2wn7A02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2wn7A01
2WN6A 4PKSA 4H0VA 4PKUA 1PWPA 1R4BA 1GZFA 4PKRA 1GIRA 1J7NA 3NTSA 5H04A 5GTTA 2WN4A 1R45A 4H0YA 4PKVA 1YQYA 5D1UA 3U0JA 2A78B 2C8HA 4GF1A 2C89A 4H0TA 1OJZA 1UZIA 5H03A 4FMLA 4XM8A 2J3XA 2A9KB 4PKWA 4DV8A 4TR5A 1GXZA 1OG3A 2C8BX 4GY2A 4XM7A 4PKTA 2C8FE 4ELNA 2WN7A 2C8DA 1ZXVA 2J3ZA 4FK7A 2C8EE 4XSGB 2GWLA 5BWMB 1GZEA 1G24A 1GIQA 1QS1A 4H03A 4PKQA 4XSHB 1PWWA 1PWUA 5D1TA 1JKYA 1OJQA 2WN5A 2C8CA 1GXYA 1PWQA 2WN8A 3BUZA 4FXQA 4WF6A 2C8GA 3BW8A 1OG4A 1OG1A 2BOVB 4H0XA 5DZQA 1QS2A 1GY0A 2J3VA 1PWVA 2C8AA 5D1SA 2GWMA 4XM6A
chains in the Genus database with same CATH superfamily
2WN6A 4PKSA 4H0VA 4PKUA 1PWPA 1R4BA 1GZFA 4PKRA 1GIRA 1J7NA 3NTSA 5H04A 5GTTA 2WN4A 1R45A 4H0YA 4PKVA 1YQYA 5D1UA 3U0JA 2A78B 2C8HA 4GF1A 2C89A 4H0TA 1OJZA 1UZIA 5H03A 4FMLA 4XM8A 2J3XA 2A9KB 4PKWA 4DV8A 4TR5A 1GXZA 1OG3A 2C8BX 4GY2A 4XM7A 4PKTA 2C8FE 4ELNA 2WN7A 2C8DA 1ZXVA 2J3ZA 4FK7A 2C8EE 4XSGB 2GWLA 5BWMB 1GZEA 1G24A 1GIQA 1QS1A 4H03A 4PKQA 4XSHB 1PWWA 1PWUA 5D1TA 1JKYA 1OJQA 2WN5A 2C8CA 1GXYA 1PWQA 2WN8A 3BUZA 4FXQA 4WF6A 2C8GA 3BW8A 1OG4A 1OG1A 2BOVB 4H0XA 5DZQA 1QS2A 1GY0A 2J3VA 1PWVA 2C8AA 5D1SA 2GWMA 4XM6A
chains in the Genus database with same CATH topology
2WN6A 4PKSA 4H0VA 4PKUA 1PWPA 1R4BA 1GZFA 4PKRA 1GIRA 1J7NA 3NTSA 5H04A 5GTTA 2WN4A 1R45A 4H0YA 4PKVA 1YQYA 5D1UA 3U0JA 2A78B 2C8HA 4GF1A 2C89A 4H0TA 1OJZA 1UZIA 5H03A 4FMLA 4XM8A 2J3XA 2A9KB 4PKWA 4DV8A 4TR5A 1GXZA 1OG3A 2C8BX 4GY2A 4XM7A 4PKTA 2C8FE 4ELNA 2WN7A 2C8DA 1ZXVA 2J3ZA 4FK7A 2C8EE 4XSGB 2GWLA 5BWMB 1GZEA 1G24A 1GIQA 1QS1A 4H03A 4PKQA 4XSHB 1PWWA 1PWUA 5D1TA 1JKYA 1OJQA 2WN5A 2C8CA 1GXYA 1PWQA 2WN8A 3BUZA 4FXQA 4WF6A 2C8GA 3BW8A 1OG4A 1OG1A 2BOVB 4H0XA 5DZQA 1QS2A 1GY0A 2J3VA 1PWVA 2C8AA 5D1SA 2GWMA 4XM6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WN6 A;  4PKS A;  4H0V A;  4PKU A;  1PWP A;  1R4B A;  1GZF A;  4PKR A;  1GIR A;  1J7N A;  3NTS A;  5H04 A;  5GTT A;  2WN4 A;  1R45 A;  4H0Y A;  4PKV A;  1YQY A;  5D1U A;  3U0J A;  2A78 B;  2C8H A;  4GF1 A;  2C89 A;  4H0T A;  1OJZ A;  1UZI A;  5H03 A;  4FML A;  4XM8 A;  2J3X A;  2A9K B;  4PKW A;  4DV8 A;  4TR5 A;  1GXZ A;  1OG3 A;  2C8B X;  4GY2 A;  4XM7 A;  4PKT A;  2C8F E;  4ELN A;  2WN7 A;  2C8D A;  1ZXV A;  2J3Z A;  4FK7 A;  2C8E E;  4XSG B;  2GWL A;  5BWM B;  1GZE A;  1G24 A;  1GIQ A;  1QS1 A;  4H03 A;  4PKQ A;  4XSH B;  1PWW A;  1PWU A;  5D1T A;  1JKY A;  1OJQ A;  2WN5 A;  2C8C A;  1GXY A;  1PWQ A;  2WN8 A;  3BUZ A;  4FXQ A;  4WF6 A;  2C8G A;  3BW8 A;  1OG4 A;  1OG1 A;  2BOV B;  4H0X A;  5DZQ A;  1QS2 A;  1GY0 A;  2J3V A;  1PWV A;  2C8A A;  5D1S A;  2GWM A;  4XM6 A; 
#chains in the Genus database with same CATH topology
 2WN6 A;  4PKS A;  4H0V A;  4PKU A;  1PWP A;  1R4B A;  1GZF A;  4PKR A;  1GIR A;  1J7N A;  3NTS A;  5H04 A;  5GTT A;  2WN4 A;  1R45 A;  4H0Y A;  4PKV A;  1YQY A;  5D1U A;  3U0J A;  2A78 B;  2C8H A;  4GF1 A;  2C89 A;  4H0T A;  1OJZ A;  1UZI A;  5H03 A;  4FML A;  4XM8 A;  2J3X A;  2A9K B;  4PKW A;  4DV8 A;  4TR5 A;  1GXZ A;  1OG3 A;  2C8B X;  4GY2 A;  4XM7 A;  4PKT A;  2C8F E;  4ELN A;  2WN7 A;  2C8D A;  1ZXV A;  2J3Z A;  4FK7 A;  2C8E E;  4XSG B;  2GWL A;  5BWM B;  1GZE A;  1G24 A;  1GIQ A;  1QS1 A;  4H03 A;  4PKQ A;  4XSH B;  1PWW A;  1PWU A;  5D1T A;  1JKY A;  1OJQ A;  2WN5 A;  2C8C A;  1GXY A;  1PWQ A;  2WN8 A;  3BUZ A;  4FXQ A;  4WF6 A;  2C8G A;  3BW8 A;  1OG4 A;  1OG1 A;  2BOV B;  4H0X A;  5DZQ A;  1QS2 A;  1GY0 A;  2J3V A;  1PWV A;  2C8A A;  5D1S A;  2GWM A;  4XM6 A; 
#chains in the Genus database with same CATH homology
 2WN6 A;  4PKS A;  4H0V A;  4PKU A;  1PWP A;  1R4B A;  1GZF A;  4PKR A;  1GIR A;  1J7N A;  3NTS A;  5H04 A;  5GTT A;  2WN4 A;  1R45 A;  4H0Y A;  4PKV A;  1YQY A;  5D1U A;  3U0J A;  2A78 B;  2C8H A;  4GF1 A;  2C89 A;  4H0T A;  1OJZ A;  1UZI A;  5H03 A;  4FML A;  4XM8 A;  2J3X A;  2A9K B;  4PKW A;  4DV8 A;  4TR5 A;  1GXZ A;  1OG3 A;  2C8B X;  4GY2 A;  4XM7 A;  4PKT A;  2C8F E;  4ELN A;  2WN7 A;  2C8D A;  1ZXV A;  2J3Z A;  4FK7 A;  2C8E E;  4XSG B;  2GWL A;  5BWM B;  1GZE A;  1G24 A;  1GIQ A;  1QS1 A;  4H03 A;  4PKQ A;  4XSH B;  1PWW A;  1PWU A;  5D1T A;  1JKY A;  1OJQ A;  2WN5 A;  2C8C A;  1GXY A;  1PWQ A;  2WN8 A;  3BUZ A;  4FXQ A;  4WF6 A;  2C8G A;  3BW8 A;  1OG4 A;  1OG1 A;  2BOV B;  4H0X A;  5DZQ A;  1QS2 A;  1GY0 A;  2J3V A;  1PWV A;  2C8A A;  5D1S A;  2GWM A;  4XM6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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