2WN7A

Structural basis for substrate recognition in the enzymatic component of adp-ribosyltransferase toxin cdta from clostridium difficile
Total Genus 132
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
132
sequence length
394
structure length
392
Chain Sequence
ERKEAERIEQKLERSEKEALESYKKDSVEISKYSQTRNYFYDYQIEANSREKEYKELRNAISKNKIDKPMYVYYFESPEKFAFNKVIRTENQNEISLEKFNEFKETIQNKLFKQDGFKDISLYEPGKGDEKPTPLLMHLKLPRNTGMLPYTNNVSTLIEQGYSIKIDKIVRIVIDGKHYIKAEASVVSSLDFKDDVSKGDSWGKANYNDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPVNNPNPELDSKITNIENALKREPIPTNLTVYRRSGPQEFGLTLTSPEYDFNKLENIDAFKSKWEGQALSYPNFISTSIGSVNMSAFAKRKIVLRITIPKGSPGAYLSAIPGYAGEYEVLLNHGSKFKINKIDSYKDGTITKLIVDATLIP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords ADP-RIBOSYLTRANSFERASE ENZYMATIC COMPONENT
publication title Structural Basis for Substrate Recognition in the Enzymatic Component of Adp-Ribosyltransferase Toxin Cdta from Clostridium Difficile.
pubmed doi rcsb
source organism Clostridium difficile
molecule tags Transferase
total genus 132
structure length 392
sequence length 394
ec nomenclature
pdb deposition date 2009-07-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2wn7A02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2wn7A01
4H0TA 4XM6A 1QS1A 4XSHB 3BUZA 2A78B 2WN6A 5H03A 4PKUA 1YQYA 1GY0A 2WN7A 2J3VA 2C8AA 2GWLA 1GXZA 4FK7A 1OG4A 2GWMA 1JKYA 1PWPA 4XM7A 5D1SA 4GF1A 5D1UA 4XSGB 4PKTA 2A9KB 4H0YA 2C8FE 2C8DA 2C8GA 1OG3A 1PWUA 2C8CA 4PKSA 4H03A 4PKRA 4GY2A 4PKWA 5D1TA 1OJZA 4PKQA 3NTSA 1OG1A 4H0VA 1PWVA 2BOVB 1GZEA 1G24A 1PWQA 4XM8A 2C8BX 4H0XA 5BWMB 2WN8A 3U0JA 1ZXVA 1GIRA 3BW8A 2J3ZA 1GXYA 4FXQA 4TR5A 1OJQA 1GZFA 1UZIA 1GIQA 1QS2A 5H04A 1PWWA 2C89A 2WN4A 1J7NA 4WF6A 5DZQA 4DV8A 4FMLA 5GTTA 2WN5A 2C8EE 1R45A 4ELNA 2C8HA 4PKVA 2J3XA 1R4BA
chains in the Genus database with same CATH superfamily
4H0TA 4XM6A 1QS1A 4XSHB 3BUZA 2A78B 2WN6A 5H03A 4PKUA 1YQYA 1GY0A 2WN7A 2J3VA 2C8AA 2GWLA 1GXZA 4FK7A 1OG4A 2GWMA 1JKYA 1PWPA 4XM7A 5D1SA 4GF1A 5D1UA 4XSGB 4PKTA 2A9KB 4H0YA 2C8FE 2C8DA 2C8GA 1OG3A 1PWUA 2C8CA 4PKSA 4H03A 4PKRA 4GY2A 4PKWA 5D1TA 1OJZA 4PKQA 3NTSA 1OG1A 4H0VA 1PWVA 2BOVB 1GZEA 1G24A 1PWQA 4XM8A 2C8BX 4H0XA 5BWMB 2WN8A 3U0JA 1ZXVA 1GIRA 3BW8A 2J3ZA 1GXYA 4FXQA 4TR5A 1OJQA 1GZFA 1UZIA 1GIQA 1QS2A 5H04A 1PWWA 2C89A 2WN4A 1J7NA 4WF6A 5DZQA 4DV8A 4FMLA 5GTTA 2WN5A 2C8EE 1R45A 4ELNA 2C8HA 4PKVA 2J3XA 1R4BA
chains in the Genus database with same CATH topology
4H0TA 4XM6A 1QS1A 4XSHB 3BUZA 2A78B 2WN6A 5H03A 4PKUA 1YQYA 1GY0A 2WN7A 2J3VA 2C8AA 2GWLA 1GXZA 4FK7A 1OG4A 2GWMA 1JKYA 1PWPA 4XM7A 5D1SA 4GF1A 5D1UA 4XSGB 4PKTA 2A9KB 4H0YA 2C8FE 2C8DA 2C8GA 1OG3A 1PWUA 2C8CA 4PKSA 4H03A 4PKRA 4GY2A 4PKWA 5D1TA 1OJZA 4PKQA 3NTSA 1OG1A 4H0VA 1PWVA 2BOVB 1GZEA 1G24A 1PWQA 4XM8A 2C8BX 4H0XA 5BWMB 2WN8A 3U0JA 1ZXVA 1GIRA 3BW8A 2J3ZA 1GXYA 4FXQA 4TR5A 1OJQA 1GZFA 1UZIA 1GIQA 1QS2A 5H04A 1PWWA 2C89A 2WN4A 1J7NA 4WF6A 5DZQA 4DV8A 4FMLA 5GTTA 2WN5A 2C8EE 1R45A 4ELNA 2C8HA 4PKVA 2J3XA 1R4BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4H0T A;  4XM6 A;  1QS1 A;  4XSH B;  3BUZ A;  2A78 B;  2WN6 A;  5H03 A;  4PKU A;  1YQY A;  1GY0 A;  2WN7 A;  2J3V A;  2C8A A;  2GWL A;  1GXZ A;  4FK7 A;  1OG4 A;  2GWM A;  1JKY A;  1PWP A;  4XM7 A;  5D1S A;  4GF1 A;  5D1U A;  4XSG B;  4PKT A;  2A9K B;  4H0Y A;  2C8F E;  2C8D A;  2C8G A;  1OG3 A;  1PWU A;  2C8C A;  4PKS A;  4H03 A;  4PKR A;  4GY2 A;  4PKW A;  5D1T A;  1OJZ A;  4PKQ A;  3NTS A;  1OG1 A;  4H0V A;  1PWV A;  2BOV B;  1GZE A;  1G24 A;  1PWQ A;  4XM8 A;  2C8B X;  4H0X A;  5BWM B;  2WN8 A;  3U0J A;  1ZXV A;  1GIR A;  3BW8 A;  2J3Z A;  1GXY A;  4FXQ A;  4TR5 A;  1OJQ A;  1GZF A;  1UZI A;  1GIQ A;  1QS2 A;  5H04 A;  1PWW A;  2C89 A;  2WN4 A;  1J7N A;  4WF6 A;  5DZQ A;  4DV8 A;  4FML A;  5GTT A;  2WN5 A;  2C8E E;  1R45 A;  4ELN A;  2C8H A;  4PKV A;  2J3X A;  1R4B A; 
#chains in the Genus database with same CATH topology
 4H0T A;  4XM6 A;  1QS1 A;  4XSH B;  3BUZ A;  2A78 B;  2WN6 A;  5H03 A;  4PKU A;  1YQY A;  1GY0 A;  2WN7 A;  2J3V A;  2C8A A;  2GWL A;  1GXZ A;  4FK7 A;  1OG4 A;  2GWM A;  1JKY A;  1PWP A;  4XM7 A;  5D1S A;  4GF1 A;  5D1U A;  4XSG B;  4PKT A;  2A9K B;  4H0Y A;  2C8F E;  2C8D A;  2C8G A;  1OG3 A;  1PWU A;  2C8C A;  4PKS A;  4H03 A;  4PKR A;  4GY2 A;  4PKW A;  5D1T A;  1OJZ A;  4PKQ A;  3NTS A;  1OG1 A;  4H0V A;  1PWV A;  2BOV B;  1GZE A;  1G24 A;  1PWQ A;  4XM8 A;  2C8B X;  4H0X A;  5BWM B;  2WN8 A;  3U0J A;  1ZXV A;  1GIR A;  3BW8 A;  2J3Z A;  1GXY A;  4FXQ A;  4TR5 A;  1OJQ A;  1GZF A;  1UZI A;  1GIQ A;  1QS2 A;  5H04 A;  1PWW A;  2C89 A;  2WN4 A;  1J7N A;  4WF6 A;  5DZQ A;  4DV8 A;  4FML A;  5GTT A;  2WN5 A;  2C8E E;  1R45 A;  4ELN A;  2C8H A;  4PKV A;  2J3X A;  1R4B A; 
#chains in the Genus database with same CATH homology
 4H0T A;  4XM6 A;  1QS1 A;  4XSH B;  3BUZ A;  2A78 B;  2WN6 A;  5H03 A;  4PKU A;  1YQY A;  1GY0 A;  2WN7 A;  2J3V A;  2C8A A;  2GWL A;  1GXZ A;  4FK7 A;  1OG4 A;  2GWM A;  1JKY A;  1PWP A;  4XM7 A;  5D1S A;  4GF1 A;  5D1U A;  4XSG B;  4PKT A;  2A9K B;  4H0Y A;  2C8F E;  2C8D A;  2C8G A;  1OG3 A;  1PWU A;  2C8C A;  4PKS A;  4H03 A;  4PKR A;  4GY2 A;  4PKW A;  5D1T A;  1OJZ A;  4PKQ A;  3NTS A;  1OG1 A;  4H0V A;  1PWV A;  2BOV B;  1GZE A;  1G24 A;  1PWQ A;  4XM8 A;  2C8B X;  4H0X A;  5BWM B;  2WN8 A;  3U0J A;  1ZXV A;  1GIR A;  3BW8 A;  2J3Z A;  1GXY A;  4FXQ A;  4TR5 A;  1OJQ A;  1GZF A;  1UZI A;  1GIQ A;  1QS2 A;  5H04 A;  1PWW A;  2C89 A;  2WN4 A;  1J7N A;  4WF6 A;  5DZQ A;  4DV8 A;  4FML A;  5GTT A;  2WN5 A;  2C8E E;  1R45 A;  4ELN A;  2C8H A;  4PKV A;  2J3X A;  1R4B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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