2A78B

Crystal structure of the c3bot-rala complex reveals a novel type of action of a bacterial exoenzyme
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
207
structure length
207
Chain Sequence
TYQEFTNIDQAKAWGNAQYKKYGLSKSEKEAIVSYTKSASEINGKLRQNKGVINGFPSNLIKQVELLDKSFNKMKTPENIMLFRGDDPAYLGTEFQNTLLNSNGTINKTAFEKAKAKFLNKDRLEYGYISTSLMNVSQFAGRPIITKFKVAKGSKAGYIDPISAFAGQLEMLLPRHSTYHIDDMRLSSDGKQIIITATMMGTAINPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Protein binding/transferase
molecule keywords Ras-related protein Ral-A
publication title Crystal structure of the C3bot-RalA complex reveals a novel type of action of a bacterial exoenzyme.
pubmed doi rcsb
source organism Homo sapiens
total genus 70
structure length 207
sequence length 207
ec nomenclature ec 2.4.2.-:
pdb deposition date 2005-07-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2a78B00
2C8CA 1OG4A 1GIQA 1YQYA 4XM7A 4ELNA 3BW8A 4H0VA 2C8FE 1OJZA 4WF6A 4XSHB 2WN6A 1GXYA 5H04A 2C8GA 4PKUA 1GZEA 2A78B 4H03A 4XSGB 1OG1A 4PKSA 2C8EE 2WN7A 1OJQA 1JKYA 5D1TA 4FK7A 1PWWA 5H03A 1PWQA 3U0JA 4GY2A 1J7NA 2A9KB 4PKRA 4XM8A 2J3VA 1R45A 1OG3A 3BUZA 1PWUA 1R4BA 2WN5A 4GF1A 2C8BX 1G24A 4DV8A 5D1UA 1QS1A 5GTTA 2BOVB 4H0YA 2C8DA 2C89A 1PWPA 2WN4A 4FMLA 1GY0A 4PKVA 4XM6A 4PKTA 4H0XA 1UZIA 5D1SA 2GWMA 3NTSA 5DZQA 2C8AA 1GZFA 5BWMB 1GIRA 1ZXVA 2GWLA 2WN8A 2J3ZA 2C8HA 4PKWA 1GXZA 1PWVA 4H0TA 2J3XA 4FXQA 4TR5A 1QS2A 4PKQA
chains in the Genus database with same CATH superfamily
2C8CA 1OG4A 1GIQA 1YQYA 4XM7A 4ELNA 3BW8A 4H0VA 2C8FE 1OJZA 4WF6A 4XSHB 2WN6A 1GXYA 5H04A 2C8GA 4PKUA 1GZEA 2A78B 4H03A 4XSGB 1OG1A 4PKSA 2C8EE 2WN7A 1OJQA 1JKYA 5D1TA 4FK7A 1PWWA 5H03A 1PWQA 3U0JA 4GY2A 1J7NA 2A9KB 4PKRA 4XM8A 2J3VA 1R45A 1OG3A 3BUZA 1PWUA 1R4BA 2WN5A 4GF1A 2C8BX 1G24A 4DV8A 5D1UA 1QS1A 5GTTA 2BOVB 4H0YA 2C8DA 2C89A 1PWPA 2WN4A 4FMLA 1GY0A 4PKVA 4XM6A 4PKTA 4H0XA 1UZIA 5D1SA 2GWMA 3NTSA 5DZQA 2C8AA 1GZFA 5BWMB 1GIRA 1ZXVA 2GWLA 2WN8A 2J3ZA 2C8HA 4PKWA 1GXZA 1PWVA 4H0TA 2J3XA 4FXQA 4TR5A 1QS2A 4PKQA
chains in the Genus database with same CATH topology
2C8CA 1OG4A 1GIQA 1YQYA 4XM7A 4ELNA 3BW8A 4H0VA 2C8FE 1OJZA 4WF6A 4XSHB 2WN6A 1GXYA 5H04A 2C8GA 4PKUA 1GZEA 2A78B 4H03A 4XSGB 1OG1A 4PKSA 2C8EE 2WN7A 1OJQA 1JKYA 5D1TA 4FK7A 1PWWA 5H03A 1PWQA 3U0JA 4GY2A 1J7NA 2A9KB 4PKRA 4XM8A 2J3VA 1R45A 1OG3A 3BUZA 1PWUA 1R4BA 2WN5A 4GF1A 2C8BX 1G24A 4DV8A 5D1UA 1QS1A 5GTTA 2BOVB 4H0YA 2C8DA 2C89A 1PWPA 2WN4A 4FMLA 1GY0A 4PKVA 4XM6A 4PKTA 4H0XA 1UZIA 5D1SA 2GWMA 3NTSA 5DZQA 2C8AA 1GZFA 5BWMB 1GIRA 1ZXVA 2GWLA 2WN8A 2J3ZA 2C8HA 4PKWA 1GXZA 1PWVA 4H0TA 2J3XA 4FXQA 4TR5A 1QS2A 4PKQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2C8C A;  1OG4 A;  1GIQ A;  1YQY A;  4XM7 A;  4ELN A;  3BW8 A;  4H0V A;  2C8F E;  1OJZ A;  4WF6 A;  4XSH B;  2WN6 A;  1GXY A;  5H04 A;  2C8G A;  4PKU A;  1GZE A;  2A78 B;  4H03 A;  4XSG B;  1OG1 A;  4PKS A;  2C8E E;  2WN7 A;  1OJQ A;  1JKY A;  5D1T A;  4FK7 A;  1PWW A;  5H03 A;  1PWQ A;  3U0J A;  4GY2 A;  1J7N A;  2A9K B;  4PKR A;  4XM8 A;  2J3V A;  1R45 A;  1OG3 A;  3BUZ A;  1PWU A;  1R4B A;  2WN5 A;  4GF1 A;  2C8B X;  1G24 A;  4DV8 A;  5D1U A;  1QS1 A;  5GTT A;  2BOV B;  4H0Y A;  2C8D A;  2C89 A;  1PWP A;  2WN4 A;  4FML A;  1GY0 A;  4PKV A;  4XM6 A;  4PKT A;  4H0X A;  1UZI A;  5D1S A;  2GWM A;  3NTS A;  5DZQ A;  2C8A A;  1GZF A;  5BWM B;  1GIR A;  1ZXV A;  2GWL A;  2WN8 A;  2J3Z A;  2C8H A;  4PKW A;  1GXZ A;  1PWV A;  4H0T A;  2J3X A;  4FXQ A;  4TR5 A;  1QS2 A;  4PKQ A; 
#chains in the Genus database with same CATH topology
 2C8C A;  1OG4 A;  1GIQ A;  1YQY A;  4XM7 A;  4ELN A;  3BW8 A;  4H0V A;  2C8F E;  1OJZ A;  4WF6 A;  4XSH B;  2WN6 A;  1GXY A;  5H04 A;  2C8G A;  4PKU A;  1GZE A;  2A78 B;  4H03 A;  4XSG B;  1OG1 A;  4PKS A;  2C8E E;  2WN7 A;  1OJQ A;  1JKY A;  5D1T A;  4FK7 A;  1PWW A;  5H03 A;  1PWQ A;  3U0J A;  4GY2 A;  1J7N A;  2A9K B;  4PKR A;  4XM8 A;  2J3V A;  1R45 A;  1OG3 A;  3BUZ A;  1PWU A;  1R4B A;  2WN5 A;  4GF1 A;  2C8B X;  1G24 A;  4DV8 A;  5D1U A;  1QS1 A;  5GTT A;  2BOV B;  4H0Y A;  2C8D A;  2C89 A;  1PWP A;  2WN4 A;  4FML A;  1GY0 A;  4PKV A;  4XM6 A;  4PKT A;  4H0X A;  1UZI A;  5D1S A;  2GWM A;  3NTS A;  5DZQ A;  2C8A A;  1GZF A;  5BWM B;  1GIR A;  1ZXV A;  2GWL A;  2WN8 A;  2J3Z A;  2C8H A;  4PKW A;  1GXZ A;  1PWV A;  4H0T A;  2J3X A;  4FXQ A;  4TR5 A;  1QS2 A;  4PKQ A; 
#chains in the Genus database with same CATH homology
 2C8C A;  1OG4 A;  1GIQ A;  1YQY A;  4XM7 A;  4ELN A;  3BW8 A;  4H0V A;  2C8F E;  1OJZ A;  4WF6 A;  4XSH B;  2WN6 A;  1GXY A;  5H04 A;  2C8G A;  4PKU A;  1GZE A;  2A78 B;  4H03 A;  4XSG B;  1OG1 A;  4PKS A;  2C8E E;  2WN7 A;  1OJQ A;  1JKY A;  5D1T A;  4FK7 A;  1PWW A;  5H03 A;  1PWQ A;  3U0J A;  4GY2 A;  1J7N A;  2A9K B;  4PKR A;  4XM8 A;  2J3V A;  1R45 A;  1OG3 A;  3BUZ A;  1PWU A;  1R4B A;  2WN5 A;  4GF1 A;  2C8B X;  1G24 A;  4DV8 A;  5D1U A;  1QS1 A;  5GTT A;  2BOV B;  4H0Y A;  2C8D A;  2C89 A;  1PWP A;  2WN4 A;  4FML A;  1GY0 A;  4PKV A;  4XM6 A;  4PKT A;  4H0X A;  1UZI A;  5D1S A;  2GWM A;  3NTS A;  5DZQ A;  2C8A A;  1GZF A;  5BWM B;  1GIR A;  1ZXV A;  2GWL A;  2WN8 A;  2J3Z A;  2C8H A;  4PKW A;  1GXZ A;  1PWV A;  4H0T A;  2J3X A;  4FXQ A;  4TR5 A;  1QS2 A;  4PKQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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