2A78B

Crystal structure of the c3bot-rala complex reveals a novel type of action of a bacterial exoenzyme
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
207
structure length
207
Chain Sequence
TYQEFTNIDQAKAWGNAQYKKYGLSKSEKEAIVSYTKSASEINGKLRQNKGVINGFPSNLIKQVELLDKSFNKMKTPENIMLFRGDDPAYLGTEFQNTLLNSNGTINKTAFEKAKAKFLNKDRLEYGYISTSLMNVSQFAGRPIITKFKVAKGSKAGYIDPISAFAGQLEMLLPRHSTYHIDDMRLSSDGKQIIITATMMGTAINPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Ras-related protein Ral-A
publication title Crystal structure of the C3bot-RalA complex reveals a novel type of action of a bacterial exoenzyme.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Protein binding/transferase
total genus 70
structure length 207
sequence length 207
ec nomenclature ec 2.4.2.-:
pdb deposition date 2005-07-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2a78B00
2C8CA 1YQYA 2WN7A 2WN5A 5H04A 2GWMA 4GY2A 4PKSA 4FMLA 2C8HA 4H03A 1J7NA 4FK7A 4PKTA 1R4BA 4TR5A 4FXQA 3NTSA 1UZIA 1JKYA 4XM6A 3U0JA 2C8EE 1QS1A 1QS2A 4XM8A 2J3VA 2GWLA 4PKVA 5D1UA 1PWPA 1GIRA 3BW8A 4XSGB 2C8AA 1OJQA 2J3ZA 1GY0A 2WN6A 5D1SA 4WF6A 4PKRA 5H03A 1GZFA 1OG1A 1R45A 2WN8A 1OG4A 5GTTA 2C8GA 1G24A 3BUZA 2C89A 2A9KB 1PWWA 1OJZA 4PKQA 1GXZA 2WN4A 4H0YA 5BWMB 1ZXVA 1PWUA 2C8FE 4H0XA 4XSHB 2J3XA 4PKUA 1GXYA 4DV8A 5D1TA 5DZQA 4PKWA 4H0VA 2C8BX 4H0TA 2BOVB 1OG3A 2A78B 1GZEA 1PWVA 4ELNA 4GF1A 1GIQA 1PWQA 4XM7A 2C8DA
chains in the Genus database with same CATH superfamily
2C8CA 1YQYA 2WN7A 2WN5A 5H04A 2GWMA 4GY2A 4PKSA 4FMLA 2C8HA 4H03A 1J7NA 4FK7A 4PKTA 1R4BA 4TR5A 4FXQA 3NTSA 1UZIA 1JKYA 4XM6A 3U0JA 2C8EE 1QS1A 1QS2A 4XM8A 2J3VA 2GWLA 4PKVA 5D1UA 1PWPA 1GIRA 3BW8A 4XSGB 2C8AA 1OJQA 2J3ZA 1GY0A 2WN6A 5D1SA 4WF6A 4PKRA 5H03A 1GZFA 1OG1A 1R45A 2WN8A 1OG4A 5GTTA 2C8GA 1G24A 3BUZA 2C89A 2A9KB 1PWWA 1OJZA 4PKQA 1GXZA 2WN4A 4H0YA 5BWMB 1ZXVA 1PWUA 2C8FE 4H0XA 4XSHB 2J3XA 4PKUA 1GXYA 4DV8A 5D1TA 5DZQA 4PKWA 4H0VA 2C8BX 4H0TA 2BOVB 1OG3A 2A78B 1GZEA 1PWVA 4ELNA 4GF1A 1GIQA 1PWQA 4XM7A 2C8DA
chains in the Genus database with same CATH topology
2C8CA 1YQYA 2WN7A 2WN5A 5H04A 2GWMA 4GY2A 4PKSA 4FMLA 2C8HA 4H03A 1J7NA 4FK7A 4PKTA 1R4BA 4TR5A 4FXQA 3NTSA 1UZIA 1JKYA 4XM6A 3U0JA 2C8EE 1QS1A 1QS2A 4XM8A 2J3VA 2GWLA 4PKVA 5D1UA 1PWPA 1GIRA 3BW8A 4XSGB 2C8AA 1OJQA 2J3ZA 1GY0A 2WN6A 5D1SA 4WF6A 4PKRA 5H03A 1GZFA 1OG1A 1R45A 2WN8A 1OG4A 5GTTA 2C8GA 1G24A 3BUZA 2C89A 2A9KB 1PWWA 1OJZA 4PKQA 1GXZA 2WN4A 4H0YA 5BWMB 1ZXVA 1PWUA 2C8FE 4H0XA 4XSHB 2J3XA 4PKUA 1GXYA 4DV8A 5D1TA 5DZQA 4PKWA 4H0VA 2C8BX 4H0TA 2BOVB 1OG3A 2A78B 1GZEA 1PWVA 4ELNA 4GF1A 1GIQA 1PWQA 4XM7A 2C8DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2C8C A;  1YQY A;  2WN7 A;  2WN5 A;  5H04 A;  2GWM A;  4GY2 A;  4PKS A;  4FML A;  2C8H A;  4H03 A;  1J7N A;  4FK7 A;  4PKT A;  1R4B A;  4TR5 A;  4FXQ A;  3NTS A;  1UZI A;  1JKY A;  4XM6 A;  3U0J A;  2C8E E;  1QS1 A;  1QS2 A;  4XM8 A;  2J3V A;  2GWL A;  4PKV A;  5D1U A;  1PWP A;  1GIR A;  3BW8 A;  4XSG B;  2C8A A;  1OJQ A;  2J3Z A;  1GY0 A;  2WN6 A;  5D1S A;  4WF6 A;  4PKR A;  5H03 A;  1GZF A;  1OG1 A;  1R45 A;  2WN8 A;  1OG4 A;  5GTT A;  2C8G A;  1G24 A;  3BUZ A;  2C89 A;  2A9K B;  1PWW A;  1OJZ A;  4PKQ A;  1GXZ A;  2WN4 A;  4H0Y A;  5BWM B;  1ZXV A;  1PWU A;  2C8F E;  4H0X A;  4XSH B;  2J3X A;  4PKU A;  1GXY A;  4DV8 A;  5D1T A;  5DZQ A;  4PKW A;  4H0V A;  2C8B X;  4H0T A;  2BOV B;  1OG3 A;  2A78 B;  1GZE A;  1PWV A;  4ELN A;  4GF1 A;  1GIQ A;  1PWQ A;  4XM7 A;  2C8D A; 
#chains in the Genus database with same CATH topology
 2C8C A;  1YQY A;  2WN7 A;  2WN5 A;  5H04 A;  2GWM A;  4GY2 A;  4PKS A;  4FML A;  2C8H A;  4H03 A;  1J7N A;  4FK7 A;  4PKT A;  1R4B A;  4TR5 A;  4FXQ A;  3NTS A;  1UZI A;  1JKY A;  4XM6 A;  3U0J A;  2C8E E;  1QS1 A;  1QS2 A;  4XM8 A;  2J3V A;  2GWL A;  4PKV A;  5D1U A;  1PWP A;  1GIR A;  3BW8 A;  4XSG B;  2C8A A;  1OJQ A;  2J3Z A;  1GY0 A;  2WN6 A;  5D1S A;  4WF6 A;  4PKR A;  5H03 A;  1GZF A;  1OG1 A;  1R45 A;  2WN8 A;  1OG4 A;  5GTT A;  2C8G A;  1G24 A;  3BUZ A;  2C89 A;  2A9K B;  1PWW A;  1OJZ A;  4PKQ A;  1GXZ A;  2WN4 A;  4H0Y A;  5BWM B;  1ZXV A;  1PWU A;  2C8F E;  4H0X A;  4XSH B;  2J3X A;  4PKU A;  1GXY A;  4DV8 A;  5D1T A;  5DZQ A;  4PKW A;  4H0V A;  2C8B X;  4H0T A;  2BOV B;  1OG3 A;  2A78 B;  1GZE A;  1PWV A;  4ELN A;  4GF1 A;  1GIQ A;  1PWQ A;  4XM7 A;  2C8D A; 
#chains in the Genus database with same CATH homology
 2C8C A;  1YQY A;  2WN7 A;  2WN5 A;  5H04 A;  2GWM A;  4GY2 A;  4PKS A;  4FML A;  2C8H A;  4H03 A;  1J7N A;  4FK7 A;  4PKT A;  1R4B A;  4TR5 A;  4FXQ A;  3NTS A;  1UZI A;  1JKY A;  4XM6 A;  3U0J A;  2C8E E;  1QS1 A;  1QS2 A;  4XM8 A;  2J3V A;  2GWL A;  4PKV A;  5D1U A;  1PWP A;  1GIR A;  3BW8 A;  4XSG B;  2C8A A;  1OJQ A;  2J3Z A;  1GY0 A;  2WN6 A;  5D1S A;  4WF6 A;  4PKR A;  5H03 A;  1GZF A;  1OG1 A;  1R45 A;  2WN8 A;  1OG4 A;  5GTT A;  2C8G A;  1G24 A;  3BUZ A;  2C89 A;  2A9K B;  1PWW A;  1OJZ A;  4PKQ A;  1GXZ A;  2WN4 A;  4H0Y A;  5BWM B;  1ZXV A;  1PWU A;  2C8F E;  4H0X A;  4XSH B;  2J3X A;  4PKU A;  1GXY A;  4DV8 A;  5D1T A;  5DZQ A;  4PKW A;  4H0V A;  2C8B X;  4H0T A;  2BOV B;  1OG3 A;  2A78 B;  1GZE A;  1PWV A;  4ELN A;  4GF1 A;  1GIQ A;  1PWQ A;  4XM7 A;  2C8D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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