4H0TA

Crystal structure of ia-adpr-actin complex
Total Genus 143
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
143
sequence length
414
structure length
414
Chain Sequence
MAFIERPEDFLKDKENAIQWEKKEAERVEKNLDTLEKEALELYKKDSEQISNYSQTRQYFYDYQIESNPREKEYKNLRNAISKNKIDKPINVYYFESPEKFAFNKEIRTENQNEISLEKFNELKETIQDKLFKQDGFKDVSLYEPGNGDEKPTPLLIHLKLPKNTGMLPYINSNDVKTLIEQDYSIKIDKIVRIVIEGKQYIKAEASIVNSLDFKDDVSKGDLWGKENYSDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPLNNPNPELDSKVNNIENALKLTPIPSNLIVYRRSGPQEFGLTLTSPEYDFNKIENIDAFKEKWEGKVITYPNFISTSIGSVNMSAFAKRKIILRINIPKDSPGAYLSAIPGYAGEYEVLLNHGSKFKINKVDSYKDGTVTKLILDATLIN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Iota toxin component Ia
publication title Arginine ADP-ribosylation mechanism based on structural snapshots of iota-toxin and actin complex
pubmed doi rcsb
source organism Clostridium perfringens
molecule tags Toxin/structural protein
total genus 143
structure length 414
sequence length 414
ec nomenclature ec 2.4.2.31: NAD(+)--protein-arginine ADP-ribosyltransferase.
pdb deposition date 2012-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4h0tA02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4h0tA01
4FMLA 1GY0A 4ELNA 1PWWA 2WN4A 1PWUA 3U0JA 1GZEA 2WN7A 1GIQA 2C89A 4H0XA 1PWPA 5DZQA 2J3ZA 4FXQA 4H0VA 2J3VA 3BUZA 5D1UA 2GWLA 4H03A 4DV8A 4XSGB 1OG4A 5H04A 1G24A 4XM8A 1ZXVA 5D1TA 2WN5A 3NTSA 4PKUA 2BOVB 5H03A 1GXYA 1OG1A 4XSHB 2J3XA 4PKTA 4PKRA 2C8HA 4H0TA 2C8GA 4XM7A 4H0YA 1GXZA 1QS2A 2WN6A 1PWVA 2C8DA 1GIRA 5GTTA 1R4BA 1OJZA 4FK7A 4GF1A 2A9KB 1QS1A 2A78B 4GY2A 1UZIA 1PWQA 1J7NA 4WF6A 4PKSA 2WN8A 1OJQA 5BWMB 4PKQA 1GZFA 4PKWA 1OG3A 1R45A 4PKVA 2C8AA 1YQYA 4XM6A 2GWMA 1JKYA 3BW8A 2C8CA 2C8BX 2C8EE 5D1SA 2C8FE 4TR5A
chains in the Genus database with same CATH superfamily
4FMLA 1GY0A 4ELNA 1PWWA 2WN4A 1PWUA 3U0JA 1GZEA 2WN7A 1GIQA 2C89A 4H0XA 1PWPA 5DZQA 2J3ZA 4FXQA 4H0VA 2J3VA 3BUZA 5D1UA 2GWLA 4H03A 4DV8A 4XSGB 1OG4A 5H04A 1G24A 4XM8A 1ZXVA 5D1TA 2WN5A 3NTSA 4PKUA 2BOVB 5H03A 1GXYA 1OG1A 4XSHB 2J3XA 4PKTA 4PKRA 2C8HA 4H0TA 2C8GA 4XM7A 4H0YA 1GXZA 1QS2A 2WN6A 1PWVA 2C8DA 1GIRA 5GTTA 1R4BA 1OJZA 4FK7A 4GF1A 2A9KB 1QS1A 2A78B 4GY2A 1UZIA 1PWQA 1J7NA 4WF6A 4PKSA 2WN8A 1OJQA 5BWMB 4PKQA 1GZFA 4PKWA 1OG3A 1R45A 4PKVA 2C8AA 1YQYA 4XM6A 2GWMA 1JKYA 3BW8A 2C8CA 2C8BX 2C8EE 5D1SA 2C8FE 4TR5A
chains in the Genus database with same CATH topology
4FMLA 1GY0A 4ELNA 1PWWA 2WN4A 1PWUA 3U0JA 1GZEA 2WN7A 1GIQA 2C89A 4H0XA 1PWPA 5DZQA 2J3ZA 4FXQA 4H0VA 2J3VA 3BUZA 5D1UA 2GWLA 4H03A 4DV8A 4XSGB 1OG4A 5H04A 1G24A 4XM8A 1ZXVA 5D1TA 2WN5A 3NTSA 4PKUA 2BOVB 5H03A 1GXYA 1OG1A 4XSHB 2J3XA 4PKTA 4PKRA 2C8HA 4H0TA 2C8GA 4XM7A 4H0YA 1GXZA 1QS2A 2WN6A 1PWVA 2C8DA 1GIRA 5GTTA 1R4BA 1OJZA 4FK7A 4GF1A 2A9KB 1QS1A 2A78B 4GY2A 1UZIA 1PWQA 1J7NA 4WF6A 4PKSA 2WN8A 1OJQA 5BWMB 4PKQA 1GZFA 4PKWA 1OG3A 1R45A 4PKVA 2C8AA 1YQYA 4XM6A 2GWMA 1JKYA 3BW8A 2C8CA 2C8BX 2C8EE 5D1SA 2C8FE 4TR5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FML A;  1GY0 A;  4ELN A;  1PWW A;  2WN4 A;  1PWU A;  3U0J A;  1GZE A;  2WN7 A;  1GIQ A;  2C89 A;  4H0X A;  1PWP A;  5DZQ A;  2J3Z A;  4FXQ A;  4H0V A;  2J3V A;  3BUZ A;  5D1U A;  2GWL A;  4H03 A;  4DV8 A;  4XSG B;  1OG4 A;  5H04 A;  1G24 A;  4XM8 A;  1ZXV A;  5D1T A;  2WN5 A;  3NTS A;  4PKU A;  2BOV B;  5H03 A;  1GXY A;  1OG1 A;  4XSH B;  2J3X A;  4PKT A;  4PKR A;  2C8H A;  4H0T A;  2C8G A;  4XM7 A;  4H0Y A;  1GXZ A;  1QS2 A;  2WN6 A;  1PWV A;  2C8D A;  1GIR A;  5GTT A;  1R4B A;  1OJZ A;  4FK7 A;  4GF1 A;  2A9K B;  1QS1 A;  2A78 B;  4GY2 A;  1UZI A;  1PWQ A;  1J7N A;  4WF6 A;  4PKS A;  2WN8 A;  1OJQ A;  5BWM B;  4PKQ A;  1GZF A;  4PKW A;  1OG3 A;  1R45 A;  4PKV A;  2C8A A;  1YQY A;  4XM6 A;  2GWM A;  1JKY A;  3BW8 A;  2C8C A;  2C8B X;  2C8E E;  5D1S A;  2C8F E;  4TR5 A; 
#chains in the Genus database with same CATH topology
 4FML A;  1GY0 A;  4ELN A;  1PWW A;  2WN4 A;  1PWU A;  3U0J A;  1GZE A;  2WN7 A;  1GIQ A;  2C89 A;  4H0X A;  1PWP A;  5DZQ A;  2J3Z A;  4FXQ A;  4H0V A;  2J3V A;  3BUZ A;  5D1U A;  2GWL A;  4H03 A;  4DV8 A;  4XSG B;  1OG4 A;  5H04 A;  1G24 A;  4XM8 A;  1ZXV A;  5D1T A;  2WN5 A;  3NTS A;  4PKU A;  2BOV B;  5H03 A;  1GXY A;  1OG1 A;  4XSH B;  2J3X A;  4PKT A;  4PKR A;  2C8H A;  4H0T A;  2C8G A;  4XM7 A;  4H0Y A;  1GXZ A;  1QS2 A;  2WN6 A;  1PWV A;  2C8D A;  1GIR A;  5GTT A;  1R4B A;  1OJZ A;  4FK7 A;  4GF1 A;  2A9K B;  1QS1 A;  2A78 B;  4GY2 A;  1UZI A;  1PWQ A;  1J7N A;  4WF6 A;  4PKS A;  2WN8 A;  1OJQ A;  5BWM B;  4PKQ A;  1GZF A;  4PKW A;  1OG3 A;  1R45 A;  4PKV A;  2C8A A;  1YQY A;  4XM6 A;  2GWM A;  1JKY A;  3BW8 A;  2C8C A;  2C8B X;  2C8E E;  5D1S A;  2C8F E;  4TR5 A; 
#chains in the Genus database with same CATH homology
 4FML A;  1GY0 A;  4ELN A;  1PWW A;  2WN4 A;  1PWU A;  3U0J A;  1GZE A;  2WN7 A;  1GIQ A;  2C89 A;  4H0X A;  1PWP A;  5DZQ A;  2J3Z A;  4FXQ A;  4H0V A;  2J3V A;  3BUZ A;  5D1U A;  2GWL A;  4H03 A;  4DV8 A;  4XSG B;  1OG4 A;  5H04 A;  1G24 A;  4XM8 A;  1ZXV A;  5D1T A;  2WN5 A;  3NTS A;  4PKU A;  2BOV B;  5H03 A;  1GXY A;  1OG1 A;  4XSH B;  2J3X A;  4PKT A;  4PKR A;  2C8H A;  4H0T A;  2C8G A;  4XM7 A;  4H0Y A;  1GXZ A;  1QS2 A;  2WN6 A;  1PWV A;  2C8D A;  1GIR A;  5GTT A;  1R4B A;  1OJZ A;  4FK7 A;  4GF1 A;  2A9K B;  1QS1 A;  2A78 B;  4GY2 A;  1UZI A;  1PWQ A;  1J7N A;  4WF6 A;  4PKS A;  2WN8 A;  1OJQ A;  5BWM B;  4PKQ A;  1GZF A;  4PKW A;  1OG3 A;  1R45 A;  4PKV A;  2C8A A;  1YQY A;  4XM6 A;  2GWM A;  1JKY A;  3BW8 A;  2C8C A;  2C8B X;  2C8E E;  5D1S A;  2C8F E;  4TR5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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