4H0TA

Crystal structure of ia-adpr-actin complex
Total Genus 143
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
143
sequence length
414
structure length
414
Chain Sequence
MAFIERPEDFLKDKENAIQWEKKEAERVEKNLDTLEKEALELYKKDSEQISNYSQTRQYFYDYQIESNPREKEYKNLRNAISKNKIDKPINVYYFESPEKFAFNKEIRTENQNEISLEKFNELKETIQDKLFKQDGFKDVSLYEPGNGDEKPTPLLIHLKLPKNTGMLPYINSNDVKTLIEQDYSIKIDKIVRIVIEGKQYIKAEASIVNSLDFKDDVSKGDLWGKENYSDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPLNNPNPELDSKVNNIENALKLTPIPSNLIVYRRSGPQEFGLTLTSPEYDFNKIENIDAFKEKWEGKVITYPNFISTSIGSVNMSAFAKRKIILRINIPKDSPGAYLSAIPGYAGEYEVLLNHGSKFKINKVDSYKDGTVTKLILDATLIN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin/structural protein
molecule keywords Iota toxin component Ia
publication title Arginine ADP-ribosylation mechanism based on structural snapshots of iota-toxin and actin complex
pubmed doi rcsb
source organism Clostridium perfringens
total genus 143
structure length 414
sequence length 414
ec nomenclature ec 2.4.2.31: NAD(+)--protein-arginine ADP-ribosyltransferase.
pdb deposition date 2012-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4h0tA02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4h0tA01
1PWQA 2A9KB 1R4BA 5DZQA 2GWMA 2C89A 1PWWA 5BWMB 3BW8A 1GXZA 2J3ZA 4FXQA 1ZXVA 5H03A 4TR5A 4ELNA 2C8AA 4FMLA 1GZEA 2C8HA 4PKVA 1OG1A 2J3XA 2J3VA 4XM6A 1QS1A 1OJQA 3U0JA 4XSHB 4GF1A 4H03A 1OJZA 5D1TA 4H0YA 4H0XA 1YQYA 4PKWA 1PWVA 2BOVB 4H0TA 2C8EE 2WN7A 5H04A 2WN6A 1QS2A 2C8CA 1GIQA 2A78B 4H0VA 4DV8A 4WF6A 4PKUA 4PKSA 3BUZA 5GTTA 2C8FE 4PKQA 1UZIA 4FK7A 2C8GA 1PWPA 2WN8A 1GIRA 1GY0A 1G24A 2C8DA 1GXYA 4XM8A 2WN5A 4PKRA 1GZFA 2C8BX 1J7NA 2WN4A 4PKTA 1R45A 5D1UA 4GY2A 2GWLA 3NTSA 5D1SA 1OG4A 1JKYA 1OG3A 4XSGB 4XM7A 1PWUA
chains in the Genus database with same CATH superfamily
1PWQA 2A9KB 1R4BA 5DZQA 2GWMA 2C89A 1PWWA 5BWMB 3BW8A 1GXZA 2J3ZA 4FXQA 1ZXVA 5H03A 4TR5A 4ELNA 2C8AA 4FMLA 1GZEA 2C8HA 4PKVA 1OG1A 2J3XA 2J3VA 4XM6A 1QS1A 1OJQA 3U0JA 4XSHB 4GF1A 4H03A 1OJZA 5D1TA 4H0YA 4H0XA 1YQYA 4PKWA 1PWVA 2BOVB 4H0TA 2C8EE 2WN7A 5H04A 2WN6A 1QS2A 2C8CA 1GIQA 2A78B 4H0VA 4DV8A 4WF6A 4PKUA 4PKSA 3BUZA 5GTTA 2C8FE 4PKQA 1UZIA 4FK7A 2C8GA 1PWPA 2WN8A 1GIRA 1GY0A 1G24A 2C8DA 1GXYA 4XM8A 2WN5A 4PKRA 1GZFA 2C8BX 1J7NA 2WN4A 4PKTA 1R45A 5D1UA 4GY2A 2GWLA 3NTSA 5D1SA 1OG4A 1JKYA 1OG3A 4XSGB 4XM7A 1PWUA
chains in the Genus database with same CATH topology
1PWQA 2A9KB 1R4BA 5DZQA 2GWMA 2C89A 1PWWA 5BWMB 3BW8A 1GXZA 2J3ZA 4FXQA 1ZXVA 5H03A 4TR5A 4ELNA 2C8AA 4FMLA 1GZEA 2C8HA 4PKVA 1OG1A 2J3XA 2J3VA 4XM6A 1QS1A 1OJQA 3U0JA 4XSHB 4GF1A 4H03A 1OJZA 5D1TA 4H0YA 4H0XA 1YQYA 4PKWA 1PWVA 2BOVB 4H0TA 2C8EE 2WN7A 5H04A 2WN6A 1QS2A 2C8CA 1GIQA 2A78B 4H0VA 4DV8A 4WF6A 4PKUA 4PKSA 3BUZA 5GTTA 2C8FE 4PKQA 1UZIA 4FK7A 2C8GA 1PWPA 2WN8A 1GIRA 1GY0A 1G24A 2C8DA 1GXYA 4XM8A 2WN5A 4PKRA 1GZFA 2C8BX 1J7NA 2WN4A 4PKTA 1R45A 5D1UA 4GY2A 2GWLA 3NTSA 5D1SA 1OG4A 1JKYA 1OG3A 4XSGB 4XM7A 1PWUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PWQ A;  2A9K B;  1R4B A;  5DZQ A;  2GWM A;  2C89 A;  1PWW A;  5BWM B;  3BW8 A;  1GXZ A;  2J3Z A;  4FXQ A;  1ZXV A;  5H03 A;  4TR5 A;  4ELN A;  2C8A A;  4FML A;  1GZE A;  2C8H A;  4PKV A;  1OG1 A;  2J3X A;  2J3V A;  4XM6 A;  1QS1 A;  1OJQ A;  3U0J A;  4XSH B;  4GF1 A;  4H03 A;  1OJZ A;  5D1T A;  4H0Y A;  4H0X A;  1YQY A;  4PKW A;  1PWV A;  2BOV B;  4H0T A;  2C8E E;  2WN7 A;  5H04 A;  2WN6 A;  1QS2 A;  2C8C A;  1GIQ A;  2A78 B;  4H0V A;  4DV8 A;  4WF6 A;  4PKU A;  4PKS A;  3BUZ A;  5GTT A;  2C8F E;  4PKQ A;  1UZI A;  4FK7 A;  2C8G A;  1PWP A;  2WN8 A;  1GIR A;  1GY0 A;  1G24 A;  2C8D A;  1GXY A;  4XM8 A;  2WN5 A;  4PKR A;  1GZF A;  2C8B X;  1J7N A;  2WN4 A;  4PKT A;  1R45 A;  5D1U A;  4GY2 A;  2GWL A;  3NTS A;  5D1S A;  1OG4 A;  1JKY A;  1OG3 A;  4XSG B;  4XM7 A;  1PWU A; 
#chains in the Genus database with same CATH topology
 1PWQ A;  2A9K B;  1R4B A;  5DZQ A;  2GWM A;  2C89 A;  1PWW A;  5BWM B;  3BW8 A;  1GXZ A;  2J3Z A;  4FXQ A;  1ZXV A;  5H03 A;  4TR5 A;  4ELN A;  2C8A A;  4FML A;  1GZE A;  2C8H A;  4PKV A;  1OG1 A;  2J3X A;  2J3V A;  4XM6 A;  1QS1 A;  1OJQ A;  3U0J A;  4XSH B;  4GF1 A;  4H03 A;  1OJZ A;  5D1T A;  4H0Y A;  4H0X A;  1YQY A;  4PKW A;  1PWV A;  2BOV B;  4H0T A;  2C8E E;  2WN7 A;  5H04 A;  2WN6 A;  1QS2 A;  2C8C A;  1GIQ A;  2A78 B;  4H0V A;  4DV8 A;  4WF6 A;  4PKU A;  4PKS A;  3BUZ A;  5GTT A;  2C8F E;  4PKQ A;  1UZI A;  4FK7 A;  2C8G A;  1PWP A;  2WN8 A;  1GIR A;  1GY0 A;  1G24 A;  2C8D A;  1GXY A;  4XM8 A;  2WN5 A;  4PKR A;  1GZF A;  2C8B X;  1J7N A;  2WN4 A;  4PKT A;  1R45 A;  5D1U A;  4GY2 A;  2GWL A;  3NTS A;  5D1S A;  1OG4 A;  1JKY A;  1OG3 A;  4XSG B;  4XM7 A;  1PWU A; 
#chains in the Genus database with same CATH homology
 1PWQ A;  2A9K B;  1R4B A;  5DZQ A;  2GWM A;  2C89 A;  1PWW A;  5BWM B;  3BW8 A;  1GXZ A;  2J3Z A;  4FXQ A;  1ZXV A;  5H03 A;  4TR5 A;  4ELN A;  2C8A A;  4FML A;  1GZE A;  2C8H A;  4PKV A;  1OG1 A;  2J3X A;  2J3V A;  4XM6 A;  1QS1 A;  1OJQ A;  3U0J A;  4XSH B;  4GF1 A;  4H03 A;  1OJZ A;  5D1T A;  4H0Y A;  4H0X A;  1YQY A;  4PKW A;  1PWV A;  2BOV B;  4H0T A;  2C8E E;  2WN7 A;  5H04 A;  2WN6 A;  1QS2 A;  2C8C A;  1GIQ A;  2A78 B;  4H0V A;  4DV8 A;  4WF6 A;  4PKU A;  4PKS A;  3BUZ A;  5GTT A;  2C8F E;  4PKQ A;  1UZI A;  4FK7 A;  2C8G A;  1PWP A;  2WN8 A;  1GIR A;  1GY0 A;  1G24 A;  2C8D A;  1GXY A;  4XM8 A;  2WN5 A;  4PKR A;  1GZF A;  2C8B X;  1J7N A;  2WN4 A;  4PKT A;  1R45 A;  5D1U A;  4GY2 A;  2GWL A;  3NTS A;  5D1S A;  1OG4 A;  1JKY A;  1OG3 A;  4XSG B;  4XM7 A;  1PWU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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