2WN6A

Structural basis for substrate recognition in the enzymatic component of adp-ribosyltransferase toxin cdta from clostridium difficile
Total Genus 136
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
136
sequence length
404
structure length
404
Chain Sequence
LKDKEKAKEWERKEAERIEQKLERSEKEALESYKKDSVEISKYSQTRNYFYDYQIEANSREKEYKELRNAISKNKIDKPMYVYYFESPEKFAFNKVIRTENQNEISLEKFNEFKETIQNKLFKQDGFKDISLWEPGKGDEKPTPLLMHLKLPRNTGMLPYTNTNNVSTLIEQGYSIKIDKIVRIVIDGKHYIKAEASVVSSLDFKDDVSKGDSWGKANYNDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPVNNPNPELDSKITNIENALKREPIPTNLTVYRRSGPQEFGLTLTSPEYDFNKLENIDAFKSKWEGQALSYPNFISTSIGSVNMSAFAKRKIVLRITIPKGSPGAYLSAIPGYAGEYEVLLNHGSKFKINKIDSYKDGTITKLIVDATLIP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords ADP-RIBOSYLTRANSFERASE ENZYMATIC COMPONENT
publication title Structural Basis for Substrate Recognition in the Enzymatic Component of Adp-Ribosyltransferase Toxin Cdta from Clostridium Difficile.
pubmed doi rcsb
source organism Clostridium difficile
total genus 136
structure length 404
sequence length 404
ec nomenclature
pdb deposition date 2009-07-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2wn6A02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2wn6A01
4H0XA 2WN8A 1R45A 1G24A 2GWMA 1GZFA 2C8EE 2WN5A 4GF1A 1QS1A 1OG1A 4XSGB 4PKUA 2GWLA 2C8CA 4XM6A 4ELNA 4PKQA 5H04A 2J3XA 4H03A 1OJQA 4H0VA 3BW8A 5H03A 1YQYA 2C8HA 1GIRA 4TR5A 1R4BA 1PWVA 1GIQA 4PKWA 2C8GA 4XM7A 1PWQA 1OG3A 1GXYA 2C8AA 1ZXVA 1J7NA 2C8FE 2J3ZA 1OJZA 4FMLA 4XM8A 4PKVA 1GZEA 1UZIA 1QS2A 4H0YA 2C89A 4PKTA 5DZQA 5GTTA 2C8BX 4FXQA 1OG4A 2C8DA 2J3VA 3BUZA 1PWWA 4DV8A 1PWUA 2A9KB 5D1UA 4PKRA 5D1SA 1PWPA 4H0TA 4GY2A 5BWMB 1GY0A 2A78B 1JKYA 4PKSA 2BOVB 4XSHB 4WF6A 2WN6A 5D1TA 3NTSA 2WN4A 1GXZA 2WN7A 3U0JA 4FK7A
chains in the Genus database with same CATH superfamily
4H0XA 2WN8A 1R45A 1G24A 2GWMA 1GZFA 2C8EE 2WN5A 4GF1A 1QS1A 1OG1A 4XSGB 4PKUA 2GWLA 2C8CA 4XM6A 4ELNA 4PKQA 5H04A 2J3XA 4H03A 1OJQA 4H0VA 3BW8A 5H03A 1YQYA 2C8HA 1GIRA 4TR5A 1R4BA 1PWVA 1GIQA 4PKWA 2C8GA 4XM7A 1PWQA 1OG3A 1GXYA 2C8AA 1ZXVA 1J7NA 2C8FE 2J3ZA 1OJZA 4FMLA 4XM8A 4PKVA 1GZEA 1UZIA 1QS2A 4H0YA 2C89A 4PKTA 5DZQA 5GTTA 2C8BX 4FXQA 1OG4A 2C8DA 2J3VA 3BUZA 1PWWA 4DV8A 1PWUA 2A9KB 5D1UA 4PKRA 5D1SA 1PWPA 4H0TA 4GY2A 5BWMB 1GY0A 2A78B 1JKYA 4PKSA 2BOVB 4XSHB 4WF6A 2WN6A 5D1TA 3NTSA 2WN4A 1GXZA 2WN7A 3U0JA 4FK7A
chains in the Genus database with same CATH topology
4H0XA 2WN8A 1R45A 1G24A 2GWMA 1GZFA 2C8EE 2WN5A 4GF1A 1QS1A 1OG1A 4XSGB 4PKUA 2GWLA 2C8CA 4XM6A 4ELNA 4PKQA 5H04A 2J3XA 4H03A 1OJQA 4H0VA 3BW8A 5H03A 1YQYA 2C8HA 1GIRA 4TR5A 1R4BA 1PWVA 1GIQA 4PKWA 2C8GA 4XM7A 1PWQA 1OG3A 1GXYA 2C8AA 1ZXVA 1J7NA 2C8FE 2J3ZA 1OJZA 4FMLA 4XM8A 4PKVA 1GZEA 1UZIA 1QS2A 4H0YA 2C89A 4PKTA 5DZQA 5GTTA 2C8BX 4FXQA 1OG4A 2C8DA 2J3VA 3BUZA 1PWWA 4DV8A 1PWUA 2A9KB 5D1UA 4PKRA 5D1SA 1PWPA 4H0TA 4GY2A 5BWMB 1GY0A 2A78B 1JKYA 4PKSA 2BOVB 4XSHB 4WF6A 2WN6A 5D1TA 3NTSA 2WN4A 1GXZA 2WN7A 3U0JA 4FK7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4H0X A;  2WN8 A;  1R45 A;  1G24 A;  2GWM A;  1GZF A;  2C8E E;  2WN5 A;  4GF1 A;  1QS1 A;  1OG1 A;  4XSG B;  4PKU A;  2GWL A;  2C8C A;  4XM6 A;  4ELN A;  4PKQ A;  5H04 A;  2J3X A;  4H03 A;  1OJQ A;  4H0V A;  3BW8 A;  5H03 A;  1YQY A;  2C8H A;  1GIR A;  4TR5 A;  1R4B A;  1PWV A;  1GIQ A;  4PKW A;  2C8G A;  4XM7 A;  1PWQ A;  1OG3 A;  1GXY A;  2C8A A;  1ZXV A;  1J7N A;  2C8F E;  2J3Z A;  1OJZ A;  4FML A;  4XM8 A;  4PKV A;  1GZE A;  1UZI A;  1QS2 A;  4H0Y A;  2C89 A;  4PKT A;  5DZQ A;  5GTT A;  2C8B X;  4FXQ A;  1OG4 A;  2C8D A;  2J3V A;  3BUZ A;  1PWW A;  4DV8 A;  1PWU A;  2A9K B;  5D1U A;  4PKR A;  5D1S A;  1PWP A;  4H0T A;  4GY2 A;  5BWM B;  1GY0 A;  2A78 B;  1JKY A;  4PKS A;  2BOV B;  4XSH B;  4WF6 A;  2WN6 A;  5D1T A;  3NTS A;  2WN4 A;  1GXZ A;  2WN7 A;  3U0J A;  4FK7 A; 
#chains in the Genus database with same CATH topology
 4H0X A;  2WN8 A;  1R45 A;  1G24 A;  2GWM A;  1GZF A;  2C8E E;  2WN5 A;  4GF1 A;  1QS1 A;  1OG1 A;  4XSG B;  4PKU A;  2GWL A;  2C8C A;  4XM6 A;  4ELN A;  4PKQ A;  5H04 A;  2J3X A;  4H03 A;  1OJQ A;  4H0V A;  3BW8 A;  5H03 A;  1YQY A;  2C8H A;  1GIR A;  4TR5 A;  1R4B A;  1PWV A;  1GIQ A;  4PKW A;  2C8G A;  4XM7 A;  1PWQ A;  1OG3 A;  1GXY A;  2C8A A;  1ZXV A;  1J7N A;  2C8F E;  2J3Z A;  1OJZ A;  4FML A;  4XM8 A;  4PKV A;  1GZE A;  1UZI A;  1QS2 A;  4H0Y A;  2C89 A;  4PKT A;  5DZQ A;  5GTT A;  2C8B X;  4FXQ A;  1OG4 A;  2C8D A;  2J3V A;  3BUZ A;  1PWW A;  4DV8 A;  1PWU A;  2A9K B;  5D1U A;  4PKR A;  5D1S A;  1PWP A;  4H0T A;  4GY2 A;  5BWM B;  1GY0 A;  2A78 B;  1JKY A;  4PKS A;  2BOV B;  4XSH B;  4WF6 A;  2WN6 A;  5D1T A;  3NTS A;  2WN4 A;  1GXZ A;  2WN7 A;  3U0J A;  4FK7 A; 
#chains in the Genus database with same CATH homology
 4H0X A;  2WN8 A;  1R45 A;  1G24 A;  2GWM A;  1GZF A;  2C8E E;  2WN5 A;  4GF1 A;  1QS1 A;  1OG1 A;  4XSG B;  4PKU A;  2GWL A;  2C8C A;  4XM6 A;  4ELN A;  4PKQ A;  5H04 A;  2J3X A;  4H03 A;  1OJQ A;  4H0V A;  3BW8 A;  5H03 A;  1YQY A;  2C8H A;  1GIR A;  4TR5 A;  1R4B A;  1PWV A;  1GIQ A;  4PKW A;  2C8G A;  4XM7 A;  1PWQ A;  1OG3 A;  1GXY A;  2C8A A;  1ZXV A;  1J7N A;  2C8F E;  2J3Z A;  1OJZ A;  4FML A;  4XM8 A;  4PKV A;  1GZE A;  1UZI A;  1QS2 A;  4H0Y A;  2C89 A;  4PKT A;  5DZQ A;  5GTT A;  2C8B X;  4FXQ A;  1OG4 A;  2C8D A;  2J3V A;  3BUZ A;  1PWW A;  4DV8 A;  1PWU A;  2A9K B;  5D1U A;  4PKR A;  5D1S A;  1PWP A;  4H0T A;  4GY2 A;  5BWM B;  1GY0 A;  2A78 B;  1JKY A;  4PKS A;  2BOV B;  4XSH B;  4WF6 A;  2WN6 A;  5D1T A;  3NTS A;  2WN4 A;  1GXZ A;  2WN7 A;  3U0J A;  4FK7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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