2C8CA

Structure of the artt motif q212a mutant c3bot1 exoenzyme (nad-bound state, crystal form i)
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
204
structure length
204
Chain Sequence
NTYQEFTNIDQAKAWGNAQYKKYGLSKSEKEAIVSYTKSASEINGKLRQNKGVINGFPSNLIKQVELLDKSFNKMKTPENIMLFRGDDPAYLGTEFQNTLLNSNGTINKTAFEKAKAKFLNKDRLEYGYISTSLMNVSQFAGRPIITKFKVAKGSKAGYIDPISAFAGALEMLLPRHSTYHIDDMRLSSDGKQIIITATMMGTA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for the Nad-Hydrolysis Mechanism and the Artt-Loop Plasticity of C3 Exoenzymes.
pubmed doi rcsb
molecule tags Transferase
source organism Clostridium botulinum
molecule keywords MONO-ADP-RIBOSYLTRANSFERASE C3
total genus 63
structure length 204
sequence length 204
chains with identical sequence B, C, D
ec nomenclature ec 2.4.2.-:
pdb deposition date 2005-12-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2c8cA00
4H0TA 5DZQA 4ELNA 5D1UA 1GXZA 4FXQA 4DV8A 1R45A 3NTSA 2C8DA 2WN8A 4GF1A 5D1TA 4XM8A 1R4BA 2J3XA 1PWWA 5H04A 2GWLA 1OJZA 1PWPA 1PWUA 4PKQA 5GTTA 2C8AA 1OG1A 1OG4A 2WN6A 2C8CA 2WN4A 5BWMB 4PKVA 1GZEA 2C8HA 1GIRA 2WN7A 1QS1A 4XSGB 2C8EE 4H03A 3U0JA 2C8GA 1JKYA 2GWMA 2J3VA 4H0YA 2A9KB 2C89A 4PKRA 4FMLA 5D1SA 4XM6A 1GIQA 2WN5A 4FK7A 3BUZA 4H0VA 1PWVA 4XM7A 4TR5A 2BOVB 4H0XA 1ZXVA 1GZFA 4WF6A 1G24A 1OJQA 2A78B 5H03A 2C8BX 1PWQA 4PKSA 1QS2A 1OG3A 4XSHB 2J3ZA 4PKUA 1YQYA 1GXYA 4PKTA 1J7NA 1GY0A 4GY2A 4PKWA 1UZIA 2C8FE 3BW8A
chains in the Genus database with same CATH superfamily
4H0TA 5DZQA 4ELNA 5D1UA 1GXZA 4FXQA 4DV8A 1R45A 3NTSA 2C8DA 2WN8A 4GF1A 5D1TA 4XM8A 1R4BA 2J3XA 1PWWA 5H04A 2GWLA 1OJZA 1PWPA 1PWUA 4PKQA 5GTTA 2C8AA 1OG1A 1OG4A 2WN6A 2C8CA 2WN4A 5BWMB 4PKVA 1GZEA 2C8HA 1GIRA 2WN7A 1QS1A 4XSGB 2C8EE 4H03A 3U0JA 2C8GA 1JKYA 2GWMA 2J3VA 4H0YA 2A9KB 2C89A 4PKRA 4FMLA 5D1SA 4XM6A 1GIQA 2WN5A 4FK7A 3BUZA 4H0VA 1PWVA 4XM7A 4TR5A 2BOVB 4H0XA 1ZXVA 1GZFA 4WF6A 1G24A 1OJQA 2A78B 5H03A 2C8BX 1PWQA 4PKSA 1QS2A 1OG3A 4XSHB 2J3ZA 4PKUA 1YQYA 1GXYA 4PKTA 1J7NA 1GY0A 4GY2A 4PKWA 1UZIA 2C8FE 3BW8A
chains in the Genus database with same CATH topology
4H0TA 5DZQA 4ELNA 5D1UA 1GXZA 4FXQA 4DV8A 1R45A 3NTSA 2C8DA 2WN8A 4GF1A 5D1TA 4XM8A 1R4BA 2J3XA 1PWWA 5H04A 2GWLA 1OJZA 1PWPA 1PWUA 4PKQA 5GTTA 2C8AA 1OG1A 1OG4A 2WN6A 2C8CA 2WN4A 5BWMB 4PKVA 1GZEA 2C8HA 1GIRA 2WN7A 1QS1A 4XSGB 2C8EE 4H03A 3U0JA 2C8GA 1JKYA 2GWMA 2J3VA 4H0YA 2A9KB 2C89A 4PKRA 4FMLA 5D1SA 4XM6A 1GIQA 2WN5A 4FK7A 3BUZA 4H0VA 1PWVA 4XM7A 4TR5A 2BOVB 4H0XA 1ZXVA 1GZFA 4WF6A 1G24A 1OJQA 2A78B 5H03A 2C8BX 1PWQA 4PKSA 1QS2A 1OG3A 4XSHB 2J3ZA 4PKUA 1YQYA 1GXYA 4PKTA 1J7NA 1GY0A 4GY2A 4PKWA 1UZIA 2C8FE 3BW8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4H0T A;  5DZQ A;  4ELN A;  5D1U A;  1GXZ A;  4FXQ A;  4DV8 A;  1R45 A;  3NTS A;  2C8D A;  2WN8 A;  4GF1 A;  5D1T A;  4XM8 A;  1R4B A;  2J3X A;  1PWW A;  5H04 A;  2GWL A;  1OJZ A;  1PWP A;  1PWU A;  4PKQ A;  5GTT A;  2C8A A;  1OG1 A;  1OG4 A;  2WN6 A;  2C8C A;  2WN4 A;  5BWM B;  4PKV A;  1GZE A;  2C8H A;  1GIR A;  2WN7 A;  1QS1 A;  4XSG B;  2C8E E;  4H03 A;  3U0J A;  2C8G A;  1JKY A;  2GWM A;  2J3V A;  4H0Y A;  2A9K B;  2C89 A;  4PKR A;  4FML A;  5D1S A;  4XM6 A;  1GIQ A;  2WN5 A;  4FK7 A;  3BUZ A;  4H0V A;  1PWV A;  4XM7 A;  4TR5 A;  2BOV B;  4H0X A;  1ZXV A;  1GZF A;  4WF6 A;  1G24 A;  1OJQ A;  2A78 B;  5H03 A;  2C8B X;  1PWQ A;  4PKS A;  1QS2 A;  1OG3 A;  4XSH B;  2J3Z A;  4PKU A;  1YQY A;  1GXY A;  4PKT A;  1J7N A;  1GY0 A;  4GY2 A;  4PKW A;  1UZI A;  2C8F E;  3BW8 A; 
#chains in the Genus database with same CATH topology
 4H0T A;  5DZQ A;  4ELN A;  5D1U A;  1GXZ A;  4FXQ A;  4DV8 A;  1R45 A;  3NTS A;  2C8D A;  2WN8 A;  4GF1 A;  5D1T A;  4XM8 A;  1R4B A;  2J3X A;  1PWW A;  5H04 A;  2GWL A;  1OJZ A;  1PWP A;  1PWU A;  4PKQ A;  5GTT A;  2C8A A;  1OG1 A;  1OG4 A;  2WN6 A;  2C8C A;  2WN4 A;  5BWM B;  4PKV A;  1GZE A;  2C8H A;  1GIR A;  2WN7 A;  1QS1 A;  4XSG B;  2C8E E;  4H03 A;  3U0J A;  2C8G A;  1JKY A;  2GWM A;  2J3V A;  4H0Y A;  2A9K B;  2C89 A;  4PKR A;  4FML A;  5D1S A;  4XM6 A;  1GIQ A;  2WN5 A;  4FK7 A;  3BUZ A;  4H0V A;  1PWV A;  4XM7 A;  4TR5 A;  2BOV B;  4H0X A;  1ZXV A;  1GZF A;  4WF6 A;  1G24 A;  1OJQ A;  2A78 B;  5H03 A;  2C8B X;  1PWQ A;  4PKS A;  1QS2 A;  1OG3 A;  4XSH B;  2J3Z A;  4PKU A;  1YQY A;  1GXY A;  4PKT A;  1J7N A;  1GY0 A;  4GY2 A;  4PKW A;  1UZI A;  2C8F E;  3BW8 A; 
#chains in the Genus database with same CATH homology
 4H0T A;  5DZQ A;  4ELN A;  5D1U A;  1GXZ A;  4FXQ A;  4DV8 A;  1R45 A;  3NTS A;  2C8D A;  2WN8 A;  4GF1 A;  5D1T A;  4XM8 A;  1R4B A;  2J3X A;  1PWW A;  5H04 A;  2GWL A;  1OJZ A;  1PWP A;  1PWU A;  4PKQ A;  5GTT A;  2C8A A;  1OG1 A;  1OG4 A;  2WN6 A;  2C8C A;  2WN4 A;  5BWM B;  4PKV A;  1GZE A;  2C8H A;  1GIR A;  2WN7 A;  1QS1 A;  4XSG B;  2C8E E;  4H03 A;  3U0J A;  2C8G A;  1JKY A;  2GWM A;  2J3V A;  4H0Y A;  2A9K B;  2C89 A;  4PKR A;  4FML A;  5D1S A;  4XM6 A;  1GIQ A;  2WN5 A;  4FK7 A;  3BUZ A;  4H0V A;  1PWV A;  4XM7 A;  4TR5 A;  2BOV B;  4H0X A;  1ZXV A;  1GZF A;  4WF6 A;  1G24 A;  1OJQ A;  2A78 B;  5H03 A;  2C8B X;  1PWQ A;  4PKS A;  1QS2 A;  1OG3 A;  4XSH B;  2J3Z A;  4PKU A;  1YQY A;  1GXY A;  4PKT A;  1J7N A;  1GY0 A;  4GY2 A;  4PKW A;  1UZI A;  2C8F E;  3BW8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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