1MB8A

Crystal structure of the actin binding domain of plectin
Total Genus 92
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
243
structure length
243
Chain Sequence
SHMAVIRIADERDRVQKKTFTKWVNKHLIKHWRAEAQRHISDLYEDLRDGHNLISLLEVLSGDSLPREKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQVSGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNAIIHRHKPLLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVSSLYDAMPRVP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural and Functional Analysis of the Actin Binding Domain of Plectin Suggests Alternative Mechanisms for Binding to F-Actin and Integrin Beta4
pubmed doi rcsb
molecule tags Structural protein
source organism Homo sapiens
molecule keywords Plectin
total genus 92
structure length 243
sequence length 243
ec nomenclature
pdb deposition date 2002-08-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00307 CH Calponin homology (CH) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 1mb8A02
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 1mb8A01
1AOAA 3CO1A 2JV9A 1AA2A 2EYIA 2D85A 2D86A 1DXXA 4Q59A 5A36A 1WYNA 3JAKM 2VZDA 3KMUB 4EDLA 1WYMA 1PA7A 5L0OA 2K2RA 5A38A 1UEGA 2RR8A 1PXYA 2L3GA 3HOPA 2R0OA 3I6XA 2DK9A 5BVRA 3JALM 2D88A 2WFNA 1UJOA 2VZIB 2EE7A 1P5SA 1WYPA 3KY9A 5J8EA 2VZCA 2WA6A 4EDNA 1WKUA 1WIXA 1WYLA 3FERA 2WA5A 2WA7A 1MB8A 1BKRA 3REPB 4B7LA 1SH5A 4TXIA 4Q57B 1BHDA 3JARM 1H67A 2D89A 2QJXA 3KMWB 1V5KA 1WYOA 2QJZA 1P2XA 1QAGA 4EDMA 1TJTA 3HORA 1WJOA 1SH6A 2R8UA 2YRNA 1VKAA 3HOCA 1RT8A 5A4BA 1WYQA 5A37A 1WYRA 2VZGB 4Q58A 4TXKA 2K3SA 3F7PA 2EYNA 2D87A 2E9KA
chains in the Genus database with same CATH superfamily
1AOAA 2HL8A 3CO1A 2JV9A 1AA2A 2EYIA 4DDPA 2D85A 2D86A 1DXXA 4Q59A 5A36A 2VE7A 1WYNA 3JAKM 2VZDA 3KMUB 4EDLA 1WYMA 1PA7A 5L0OA 2K2RA 5A38A 2HL9A 1UEGA 2RR8A 1PXYA 2L3GA 3HOPA 2R0OA 3I6XA 2DK9A 2IGPA 5BVRA 3JALM 2D88A 1EUVA 1UJOA 2WFNA 2VZIB 2EE7A 1P5SA 3EAYA 4LVRA 1WYPA 3KY9A 5J8EA 2VZCA 2WA6A 4EDNA 2HKPA 1WKUA 1WIXA 1WYLA 3FERA 2WA5A 2WA7A 1MB8A 1BKRA 3REPB 2WDTA 4B7LA 1SH5A 4TXIA 4Q57B 1BHDA 3JARM 1H67A 2D89A 2QJXA 3KMWB 1V5KA 1WYOA 2QJZA 1P2XA 1QAGA 4EDMA 1TJTA 3HORA 1WJOA 5FMTA 1SH6A 2R8UA 5FMUA 2YRNA 1VKAA 3HOCA 1RT8A 5A4BA 2EQOA 3VP7A 1WYQA 5A37A 1WYRA 2VZGB 2WE6A 4Q58A 4TXKA 2K3SA 2VE7C 3F7PA 2EYNA 2D87A 4LVPA 2E9KA
chains in the Genus database with same CATH topology
1AOAA 3CO1A 2JV9A 1AA2A 2EYIA 2D85A 2D86A 1DXXA 4Q59A 5A36A 1WYNA 3JAKM 2VZDA 3KMUB 4EDLA 1WYMA 1PA7A 5L0OA 2K2RA 5A38A 1UEGA 2RR8A 1PXYA 2L3GA 3HOPA 2R0OA 3I6XA 2DK9A 5BVRA 3JALM 2D88A 2WFNA 1UJOA 2VZIB 2EE7A 1P5SA 1WYPA 3KY9A 5J8EA 2VZCA 2WA6A 4EDNA 1WKUA 1WIXA 1WYLA 3FERA 2WA5A 2WA7A 1MB8A 1BKRA 3REPB 4B7LA 1SH5A 4TXIA 4Q57B 1BHDA 3JARM 1H67A 2D89A 2QJXA 3KMWB 1V5KA 1WYOA 2QJZA 1P2XA 1QAGA 4EDMA 1TJTA 3HORA 1WJOA 1SH6A 2R8UA 2YRNA 1VKAA 3HOCA 1RT8A 5A4BA 1WYQA 5A37A 1WYRA 2VZGB 4Q58A 4TXKA 2K3SA 3F7PA 2EYNA 2D87A 2E9KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AOA A;  3CO1 A;  2JV9 A;  1AA2 A;  2EYI A;  2D85 A;  2D86 A;  1DXX A;  4Q59 A;  5A36 A;  1WYN A;  3JAK M;  2VZD A;  3KMU B;  4EDL A;  1WYM A;  1PA7 A;  5L0O A;  2K2R A;  5A38 A;  1UEG A;  2RR8 A;  1PXY A;  2L3G A;  3HOP A;  2R0O A;  3I6X A;  2DK9 A;  5BVR A;  3JAL M;  2D88 A;  2WFN A;  1UJO A;  2VZI B;  2EE7 A;  1P5S A;  1WYP A;  3KY9 A;  5J8E A;  2VZC A;  2WA6 A;  4EDN A;  1WKU A;  1WIX A;  1WYL A;  3FER A;  2WA5 A;  2WA7 A;  1MB8 A;  1BKR A;  3REP B;  4B7L A;  1SH5 A;  4TXI A;  4Q57 B;  1BHD A;  3JAR M;  1H67 A;  2D89 A;  2QJX A;  3KMW B;  1V5K A;  1WYO A;  2QJZ A;  1P2X A;  1QAG A;  4EDM A;  1TJT A;  3HOR A;  1WJO A;  1SH6 A;  2R8U A;  2YRN A;  1VKA A;  3HOC A;  1RT8 A;  5A4B A;  1WYQ A;  5A37 A;  1WYR A;  2VZG B;  4Q58 A;  4TXK A;  2K3S A;  3F7P A;  2EYN A;  2D87 A;  2E9K A; 
#chains in the Genus database with same CATH topology
 1AOA A;  2HL8 A;  3CO1 A;  2JV9 A;  1AA2 A;  2EYI A;  4DDP A;  2D85 A;  2D86 A;  1DXX A;  4Q59 A;  5A36 A;  2VE7 A;  1WYN A;  3JAK M;  2VZD A;  3KMU B;  4EDL A;  1WYM A;  1PA7 A;  5L0O A;  2K2R A;  5A38 A;  2HL9 A;  1UEG A;  2RR8 A;  1PXY A;  2L3G A;  3HOP A;  2R0O A;  3I6X A;  2DK9 A;  2IGP A;  5BVR A;  3JAL M;  2D88 A;  1EUV A;  1UJO A;  2WFN A;  2VZI B;  2EE7 A;  1P5S A;  3EAY A;  4LVR A;  1WYP A;  3KY9 A;  5J8E A;  2VZC A;  2WA6 A;  4EDN A;  2HKP A;  1WKU A;  1WIX A;  1WYL A;  3FER A;  2WA5 A;  2WA7 A;  1MB8 A;  1BKR A;  3REP B;  2WDT A;  4B7L A;  1SH5 A;  4TXI A;  4Q57 B;  1BHD A;  3JAR M;  1H67 A;  2D89 A;  2QJX A;  3KMW B;  1V5K A;  1WYO A;  2QJZ A;  1P2X A;  1QAG A;  4EDM A;  1TJT A;  3HOR A;  1WJO A;  5FMT A;  1SH6 A;  2R8U A;  5FMU A;  2YRN A;  1VKA A;  3HOC A;  1RT8 A;  5A4B A;  2EQO A;  3VP7 A;  1WYQ A;  5A37 A;  1WYR A;  2VZG B;  2WE6 A;  4Q58 A;  4TXK A;  2K3S A;  2VE7 C;  3F7P A;  2EYN A;  2D87 A;  4LVP A;  2E9K A; 
#chains in the Genus database with same CATH homology
 1AOA A;  3CO1 A;  2JV9 A;  1AA2 A;  2EYI A;  2D85 A;  2D86 A;  1DXX A;  4Q59 A;  5A36 A;  1WYN A;  3JAK M;  2VZD A;  3KMU B;  4EDL A;  1WYM A;  1PA7 A;  5L0O A;  2K2R A;  5A38 A;  1UEG A;  2RR8 A;  1PXY A;  2L3G A;  3HOP A;  2R0O A;  3I6X A;  2DK9 A;  5BVR A;  3JAL M;  2D88 A;  2WFN A;  1UJO A;  2VZI B;  2EE7 A;  1P5S A;  1WYP A;  3KY9 A;  5J8E A;  2VZC A;  2WA6 A;  4EDN A;  1WKU A;  1WIX A;  1WYL A;  3FER A;  2WA5 A;  2WA7 A;  1MB8 A;  1BKR A;  3REP B;  4B7L A;  1SH5 A;  4TXI A;  4Q57 B;  1BHD A;  3JAR M;  1H67 A;  2D89 A;  2QJX A;  3KMW B;  1V5K A;  1WYO A;  2QJZ A;  1P2X A;  1QAG A;  4EDM A;  1TJT A;  3HOR A;  1WJO A;  1SH6 A;  2R8U A;  2YRN A;  1VKA A;  3HOC A;  1RT8 A;  5A4B A;  1WYQ A;  5A37 A;  1WYR A;  2VZG B;  4Q58 A;  4TXK A;  2K3S A;  3F7P A;  2EYN A;  2D87 A;  2E9K A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...