2K2RA

The nmr structure of alpha-parvin ch2/paxillin ld1 complex
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
129
structure length
129
Chain Sequence
RHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Structure of {alpha}-Parvin CH2-Paxillin LD1 Complex Reveals a Novel Modular Recognition for Focal Adhesion Assembly.
pubmed doi rcsb
molecule tags Cell adhesion
source organism Homo sapiens
molecule keywords Alpha-parvin
total genus 35
structure length 129
sequence length 129
ec nomenclature
pdb deposition date 2008-04-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00307 CH Calponin homology (CH) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 2k2rA00
2QJZA 2VZGB 2WA5A 2QJXA 2VZCA 1P5SA 2D85A 2RR8A 3I6XA 2VZDA 1UEGA 1PXYA 2VZIB 4B7LA 2JV9A 1WYRA 4EDMA 2R0OA 2K2RA 2YRNA 1P2XA 1QAGA 4TXIA 2WA6A 3JAKM 3HOCA 3JALM 3KY9A 3KMUB 1TJTA 5A37A 5A38A 1DXXA 3HOPA 1WYPA 1SH5A 1SH6A 1BHDA 2WFNA 4Q58A 4TXKA 5L0OA 1AOAA 2K3SA 4Q59A 1RT8A 1WYNA 4Q57B 2E9KA 1UJOA 2L3GA 5BVRA 1MB8A 2D86A 2D87A 1V5KA 2EE7A 5A4BA 2DK9A 1WKUA 3FERA 3HORA 1WYMA 1WJOA 1WYQA 1BKRA 1WYOA 2D88A 3CO1A 4EDNA 1PA7A 1H67A 2EYNA 2EYIA 3REPB 1WYLA 3KMWB 2WA7A 1WIXA 4EDLA 5J8EA 5A36A 1AA2A 2D89A 2R8UA 3F7PA 1VKAA 3JARM
chains in the Genus database with same CATH superfamily
2QJZA 2VZGB 2WA5A 2QJXA 2VZCA 1P5SA 2D85A 2RR8A 3I6XA 2HKPA 2IGPA 2VZDA 1UEGA 1PXYA 2VZIB 4B7LA 2JV9A 1WYRA 3VP7A 4EDMA 2R0OA 2K2RA 2YRNA 1P2XA 1QAGA 2HL8A 4TXIA 3EAYA 2WA6A 3JAKM 3HOCA 3JALM 3KY9A 3KMUB 1TJTA 5A37A 5A38A 2EQOA 1DXXA 3HOPA 1WYPA 1SH5A 1SH6A 1BHDA 2WFNA 4Q58A 4TXKA 5L0OA 1AOAA 2K3SA 4Q59A 1RT8A 5FMTA 1WYNA 2HL9A 2E9KA 4Q57B 1UJOA 2L3GA 5BVRA 1MB8A 1EUVA 2D86A 2D87A 1V5KA 2EE7A 5A4BA 2DK9A 2VE7C 1WKUA 3FERA 3HORA 1WYMA 1WJOA 2VE7A 1WYQA 1BKRA 1WYOA 3JARM 2D88A 3CO1A 4EDNA 1PA7A 4LVRA 1H67A 2EYNA 2EYIA 5FMUA 3REPB 1WYLA 3KMWB 4DDPA 2WA7A 2WE6A 4LVPA 1WIXA 4EDLA 5J8EA 5A36A 2D89A 2R8UA 3F7PA 1VKAA 2WDTA 1AA2A
chains in the Genus database with same CATH topology
2QJZA 2VZGB 2WA5A 2QJXA 2VZCA 1P5SA 2D85A 2RR8A 3I6XA 2VZDA 1UEGA 1PXYA 2VZIB 4B7LA 2JV9A 1WYRA 4EDMA 2R0OA 2K2RA 2YRNA 1P2XA 1QAGA 4TXIA 2WA6A 3JAKM 3HOCA 3JALM 3KY9A 3KMUB 1TJTA 5A37A 5A38A 1DXXA 3HOPA 1WYPA 1SH5A 1SH6A 1BHDA 2WFNA 4Q58A 4TXKA 5L0OA 1AOAA 2K3SA 4Q59A 1RT8A 1WYNA 4Q57B 2E9KA 1UJOA 2L3GA 5BVRA 1MB8A 2D86A 2D87A 1V5KA 2EE7A 5A4BA 2DK9A 1WKUA 3FERA 3HORA 1WYMA 1WJOA 1WYQA 1BKRA 1WYOA 2D88A 3CO1A 4EDNA 1PA7A 1H67A 2EYNA 2EYIA 3REPB 1WYLA 3KMWB 2WA7A 1WIXA 4EDLA 5J8EA 5A36A 1AA2A 2D89A 2R8UA 3F7PA 1VKAA 3JARM
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QJZ A;  2VZG B;  2WA5 A;  2QJX A;  2VZC A;  1P5S A;  2D85 A;  2RR8 A;  3I6X A;  2VZD A;  1UEG A;  1PXY A;  2VZI B;  4B7L A;  2JV9 A;  1WYR A;  4EDM A;  2R0O A;  2K2R A;  2YRN A;  1P2X A;  1QAG A;  4TXI A;  2WA6 A;  3JAK M;  3HOC A;  3JAL M;  3KY9 A;  3KMU B;  1TJT A;  5A37 A;  5A38 A;  1DXX A;  3HOP A;  1WYP A;  1SH5 A;  1SH6 A;  1BHD A;  2WFN A;  4Q58 A;  4TXK A;  5L0O A;  1AOA A;  2K3S A;  4Q59 A;  1RT8 A;  1WYN A;  4Q57 B;  2E9K A;  1UJO A;  2L3G A;  5BVR A;  1MB8 A;  2D86 A;  2D87 A;  1V5K A;  2EE7 A;  5A4B A;  2DK9 A;  1WKU A;  3FER A;  3HOR A;  1WYM A;  1WJO A;  1WYQ A;  1BKR A;  1WYO A;  2D88 A;  3CO1 A;  4EDN A;  1PA7 A;  1H67 A;  2EYN A;  2EYI A;  3REP B;  1WYL A;  3KMW B;  2WA7 A;  1WIX A;  4EDL A;  5J8E A;  5A36 A;  1AA2 A;  2D89 A;  2R8U A;  3F7P A;  1VKA A;  3JAR M; 
#chains in the Genus database with same CATH topology
 2QJZ A;  2VZG B;  2WA5 A;  2QJX A;  2VZC A;  1P5S A;  2D85 A;  2RR8 A;  3I6X A;  2HKP A;  2IGP A;  2VZD A;  1UEG A;  1PXY A;  2VZI B;  4B7L A;  2JV9 A;  1WYR A;  3VP7 A;  4EDM A;  2R0O A;  2K2R A;  2YRN A;  1P2X A;  1QAG A;  2HL8 A;  4TXI A;  3EAY A;  2WA6 A;  3JAK M;  3HOC A;  3JAL M;  3KY9 A;  3KMU B;  1TJT A;  5A37 A;  5A38 A;  2EQO A;  1DXX A;  3HOP A;  1WYP A;  1SH5 A;  1SH6 A;  1BHD A;  2WFN A;  4Q58 A;  4TXK A;  5L0O A;  1AOA A;  2K3S A;  4Q59 A;  1RT8 A;  5FMT A;  1WYN A;  2HL9 A;  2E9K A;  4Q57 B;  1UJO A;  2L3G A;  5BVR A;  1MB8 A;  1EUV A;  2D86 A;  2D87 A;  1V5K A;  2EE7 A;  5A4B A;  2DK9 A;  2VE7 C;  1WKU A;  3FER A;  3HOR A;  1WYM A;  1WJO A;  2VE7 A;  1WYQ A;  1BKR A;  1WYO A;  3JAR M;  2D88 A;  3CO1 A;  4EDN A;  1PA7 A;  4LVR A;  1H67 A;  2EYN A;  2EYI A;  5FMU A;  3REP B;  1WYL A;  3KMW B;  4DDP A;  2WA7 A;  2WE6 A;  4LVP A;  1WIX A;  4EDL A;  5J8E A;  5A36 A;  2D89 A;  2R8U A;  3F7P A;  1VKA A;  2WDT A;  1AA2 A; 
#chains in the Genus database with same CATH homology
 2QJZ A;  2VZG B;  2WA5 A;  2QJX A;  2VZC A;  1P5S A;  2D85 A;  2RR8 A;  3I6X A;  2VZD A;  1UEG A;  1PXY A;  2VZI B;  4B7L A;  2JV9 A;  1WYR A;  4EDM A;  2R0O A;  2K2R A;  2YRN A;  1P2X A;  1QAG A;  4TXI A;  2WA6 A;  3JAK M;  3HOC A;  3JAL M;  3KY9 A;  3KMU B;  1TJT A;  5A37 A;  5A38 A;  1DXX A;  3HOP A;  1WYP A;  1SH5 A;  1SH6 A;  1BHD A;  2WFN A;  4Q58 A;  4TXK A;  5L0O A;  1AOA A;  2K3S A;  4Q59 A;  1RT8 A;  1WYN A;  4Q57 B;  2E9K A;  1UJO A;  2L3G A;  5BVR A;  1MB8 A;  2D86 A;  2D87 A;  1V5K A;  2EE7 A;  5A4B A;  2DK9 A;  1WKU A;  3FER A;  3HOR A;  1WYM A;  1WJO A;  1WYQ A;  1BKR A;  1WYO A;  2D88 A;  3CO1 A;  4EDN A;  1PA7 A;  1H67 A;  2EYN A;  2EYI A;  3REP B;  1WYL A;  3KMW B;  2WA7 A;  1WIX A;  4EDL A;  5J8E A;  5A36 A;  1AA2 A;  2D89 A;  2R8U A;  3F7P A;  1VKA A;  3JAR M; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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