1P5SA

Structure and function of the calponin-homology domain of an iqgap protein from schizosaccharomyces pombe
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
159
structure length
159
Chain Sequence
RETLQAYDYLCRVDEAKKWIEECLGTDLGPTSTFEQSLRNGVVLALLVQKFQPDKLIKIFYSNELQFRHSDNINKFLDFIHGIGLPEIFHFELTDIYEGKNLPKVIYCIHALSYFLSMQDLAPPLIKSDENLSFTDEDVSIIVRRLRQSNVILPNFKAL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure, crystal packing and molecular dynamics of the calponin-homology domain of Schizosaccharomyces pombe Rng2.
pubmed doi rcsb
molecule tags Cytokine
source organism Schizosaccharomyces pombe
molecule keywords Ras GTPase-activating-like protein rng2
total genus 53
structure length 159
sequence length 159
ec nomenclature
pdb deposition date 2003-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00307 CH Calponin homology (CH) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 1p5sA00
1SH5A 1AA2A 1BHDA 2WA7A 1P5SA 1UEGA 4EDLA 2YRNA 5A4BA 3JALM 2JV9A 2D86A 5A36A 4EDMA 2VZGB 3HORA 2RR8A 2EYIA 1QAGA 4TXIA 1PA7A 5BVRA 1SH6A 2QJZA 1WJOA 3KY9A 1WYNA 4Q57B 2L3GA 2D87A 3HOPA 2D88A 2K2RA 2VZIB 1VKAA 1WIXA 1TJTA 1WYLA 1MB8A 2EYNA 2R0OA 3JAKM 2R8UA 2WFNA 1BKRA 4Q59A 4TXKA 2EE7A 5A38A 2WA6A 1H67A 3KMUB 1DXXA 1WKUA 2VZDA 2DK9A 4Q58A 1WYRA 2K3SA 1WYOA 2QJXA 1RT8A 5L0OA 5J8EA 3I6XA 1AOAA 1V5KA 3FERA 3CO1A 2VZCA 1WYPA 2D85A 1UJOA 4EDNA 5A37A 2WA5A 4B7LA 2D89A 2E9KA 1P2XA 1WYQA 1WYMA 3KMWB 3JARM 3HOCA 3REPB 1PXYA 3F7PA
chains in the Genus database with same CATH superfamily
1SH5A 1AA2A 1BHDA 2WA7A 1P5SA 1UEGA 4EDLA 2YRNA 5A4BA 3JALM 2HKPA 2JV9A 2D86A 5A36A 4EDMA 3VP7A 2VZGB 3HORA 2RR8A 2EYIA 2HL9A 1QAGA 4TXIA 1PA7A 5BVRA 1SH6A 2QJZA 1WJOA 3KY9A 4LVPA 2WE6A 1WYNA 4Q57B 2WDTA 2L3GA 2D87A 3HOPA 2D88A 2K2RA 2VZIB 1VKAA 1WIXA 1TJTA 1WYLA 3EAYA 1MB8A 2VE7A 2EYNA 2R0OA 3JAKM 2R8UA 2WFNA 1BKRA 4Q59A 2EE7A 4TXKA 5A38A 1EUVA 2WA6A 1H67A 4DDPA 3KMUB 1DXXA 1WKUA 2VZDA 2DK9A 5FMUA 4Q58A 1WYRA 2K3SA 1WYOA 2QJXA 1RT8A 5L0OA 5J8EA 3I6XA 1AOAA 1V5KA 3FERA 4LVRA 2IGPA 2VZCA 3CO1A 1WYPA 2D85A 1UJOA 2HL8A 4EDNA 5A37A 2WA5A 2EQOA 4B7LA 2D89A 2E9KA 2VE7C 5FMTA 1P2XA 1WYQA 1WYMA 3KMWB 3JARM 3HOCA 3REPB 1PXYA 3F7PA
chains in the Genus database with same CATH topology
1SH5A 1AA2A 1BHDA 2WA7A 1P5SA 1UEGA 4EDLA 2YRNA 5A4BA 3JALM 2JV9A 2D86A 5A36A 4EDMA 2VZGB 3HORA 2RR8A 2EYIA 1QAGA 4TXIA 1PA7A 5BVRA 1SH6A 2QJZA 1WJOA 3KY9A 1WYNA 4Q57B 2L3GA 2D87A 3HOPA 2D88A 2K2RA 2VZIB 1VKAA 1WIXA 1TJTA 1WYLA 1MB8A 2EYNA 2R0OA 3JAKM 2R8UA 2WFNA 1BKRA 4Q59A 4TXKA 2EE7A 5A38A 2WA6A 1H67A 3KMUB 1DXXA 1WKUA 2VZDA 2DK9A 4Q58A 1WYRA 2K3SA 1WYOA 2QJXA 1RT8A 5L0OA 5J8EA 3I6XA 1AOAA 1V5KA 3FERA 3CO1A 2VZCA 1WYPA 2D85A 1UJOA 4EDNA 5A37A 2WA5A 4B7LA 2D89A 2E9KA 1P2XA 1WYQA 1WYMA 3KMWB 3JARM 3HOCA 3REPB 1PXYA 3F7PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SH5 A;  1AA2 A;  1BHD A;  2WA7 A;  1P5S A;  1UEG A;  4EDL A;  2YRN A;  5A4B A;  3JAL M;  2JV9 A;  2D86 A;  5A36 A;  4EDM A;  2VZG B;  3HOR A;  2RR8 A;  2EYI A;  1QAG A;  4TXI A;  1PA7 A;  5BVR A;  1SH6 A;  2QJZ A;  1WJO A;  3KY9 A;  1WYN A;  4Q57 B;  2L3G A;  2D87 A;  3HOP A;  2D88 A;  2K2R A;  2VZI B;  1VKA A;  1WIX A;  1TJT A;  1WYL A;  1MB8 A;  2EYN A;  2R0O A;  3JAK M;  2R8U A;  2WFN A;  1BKR A;  4Q59 A;  4TXK A;  2EE7 A;  5A38 A;  2WA6 A;  1H67 A;  3KMU B;  1DXX A;  1WKU A;  2VZD A;  2DK9 A;  4Q58 A;  1WYR A;  2K3S A;  1WYO A;  2QJX A;  1RT8 A;  5L0O A;  5J8E A;  3I6X A;  1AOA A;  1V5K A;  3FER A;  3CO1 A;  2VZC A;  1WYP A;  2D85 A;  1UJO A;  4EDN A;  5A37 A;  2WA5 A;  4B7L A;  2D89 A;  2E9K A;  1P2X A;  1WYQ A;  1WYM A;  3KMW B;  3JAR M;  3HOC A;  3REP B;  1PXY A;  3F7P A; 
#chains in the Genus database with same CATH topology
 1SH5 A;  1AA2 A;  1BHD A;  2WA7 A;  1P5S A;  1UEG A;  4EDL A;  2YRN A;  5A4B A;  3JAL M;  2HKP A;  2JV9 A;  2D86 A;  5A36 A;  4EDM A;  3VP7 A;  2VZG B;  3HOR A;  2RR8 A;  2EYI A;  2HL9 A;  1QAG A;  4TXI A;  1PA7 A;  5BVR A;  1SH6 A;  2QJZ A;  1WJO A;  3KY9 A;  4LVP A;  2WE6 A;  1WYN A;  4Q57 B;  2WDT A;  2L3G A;  2D87 A;  3HOP A;  2D88 A;  2K2R A;  2VZI B;  1VKA A;  1WIX A;  1TJT A;  1WYL A;  3EAY A;  1MB8 A;  2VE7 A;  2EYN A;  2R0O A;  3JAK M;  2R8U A;  2WFN A;  1BKR A;  4Q59 A;  2EE7 A;  4TXK A;  5A38 A;  1EUV A;  2WA6 A;  1H67 A;  4DDP A;  3KMU B;  1DXX A;  1WKU A;  2VZD A;  2DK9 A;  5FMU A;  4Q58 A;  1WYR A;  2K3S A;  1WYO A;  2QJX A;  1RT8 A;  5L0O A;  5J8E A;  3I6X A;  1AOA A;  1V5K A;  3FER A;  4LVR A;  2IGP A;  2VZC A;  3CO1 A;  1WYP A;  2D85 A;  1UJO A;  2HL8 A;  4EDN A;  5A37 A;  2WA5 A;  2EQO A;  4B7L A;  2D89 A;  2E9K A;  2VE7 C;  5FMT A;  1P2X A;  1WYQ A;  1WYM A;  3KMW B;  3JAR M;  3HOC A;  3REP B;  1PXY A;  3F7P A; 
#chains in the Genus database with same CATH homology
 1SH5 A;  1AA2 A;  1BHD A;  2WA7 A;  1P5S A;  1UEG A;  4EDL A;  2YRN A;  5A4B A;  3JAL M;  2JV9 A;  2D86 A;  5A36 A;  4EDM A;  2VZG B;  3HOR A;  2RR8 A;  2EYI A;  1QAG A;  4TXI A;  1PA7 A;  5BVR A;  1SH6 A;  2QJZ A;  1WJO A;  3KY9 A;  1WYN A;  4Q57 B;  2L3G A;  2D87 A;  3HOP A;  2D88 A;  2K2R A;  2VZI B;  1VKA A;  1WIX A;  1TJT A;  1WYL A;  1MB8 A;  2EYN A;  2R0O A;  3JAK M;  2R8U A;  2WFN A;  1BKR A;  4Q59 A;  4TXK A;  2EE7 A;  5A38 A;  2WA6 A;  1H67 A;  3KMU B;  1DXX A;  1WKU A;  2VZD A;  2DK9 A;  4Q58 A;  1WYR A;  2K3S A;  1WYO A;  2QJX A;  1RT8 A;  5L0O A;  5J8E A;  3I6X A;  1AOA A;  1V5K A;  3FER A;  3CO1 A;  2VZC A;  1WYP A;  2D85 A;  1UJO A;  4EDN A;  5A37 A;  2WA5 A;  4B7L A;  2D89 A;  2E9K A;  1P2X A;  1WYQ A;  1WYM A;  3KMW B;  3JAR M;  3HOC A;  3REP B;  1PXY A;  3F7P A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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