1QAGA

Actin binding region of the dystrophin homologue utrophin
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
226
structure length
226
Chain Sequence
DVQKKTFTKWINARFSKSGKPPINDMFTDLKDGRKLLDLLEGLTGTSLPKERGSTRVHALNNVNRVLQVLHQNNVELVNIGGTDIVDGNHKLTLGLLWSIILHWQVKDVMKDVMSDLQQTNSEKILLSWVRQTTRPYSQVNVLNFTTSWTDGLAFNAVLHRHKPDLFSWDKVVKMSPIERLEHAFSKAQTYLGIEKLLDPEDVAVRLPDKKSIIMYLTSLFEVLPQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the actin-binding region of utrophin reveals a head-to-tail dimer
pubmed doi rcsb
molecule tags Structural protein
source organism Homo sapiens
molecule keywords UTROPHIN ACTIN BINDING REGION
total genus 69
structure length 226
sequence length 226
chains with identical sequence B
ec nomenclature
pdb deposition date 1999-03-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00307 CH Calponin homology (CH) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 1qagA02
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 1qagA01
2VZCA 3KMUB 4B7LA 2JV9A 2D89A 3JALM 4TXKA 2WA6A 1WYNA 3I6XA 1WJOA 1WIXA 1SH6A 1WYMA 3REPB 4EDLA 1PA7A 2QJZA 2VZGB 3KY9A 1TJTA 1VKAA 1MB8A 2WA5A 1QAGA 1WYRA 2K3SA 5A37A 2E9KA 1PXYA 1BHDA 2K2RA 1WYQA 2D85A 1P2XA 4TXIA 1BKRA 5J8EA 3HOCA 2EYIA 4Q59A 3F7PA 4EDNA 1WYLA 2R8UA 2D88A 1H67A 1WKUA 5A38A 4Q57B 1V5KA 1DXXA 5BVRA 2RR8A 3FERA 2QJXA 1UJOA 3HOPA 1WYPA 1RT8A 4EDMA 1AA2A 3CO1A 2R0OA 2WFNA 1SH5A 3JAKM 2VZDA 1WYOA 2D87A 1P5SA 5A4BA 2EE7A 2EYNA 4Q58A 5A36A 3KMWB 2WA7A 2L3GA 2YRNA 2D86A 2DK9A 1UEGA 3HORA 2VZIB 5L0OA 1AOAA 3JARM
chains in the Genus database with same CATH superfamily
2VZCA 2IGPA 2VE7C 3KMUB 4B7LA 2JV9A 2D89A 3JALM 4TXKA 2WA6A 1WYNA 3I6XA 1WJOA 1WIXA 1SH6A 1WYMA 3REPB 4EDLA 1PA7A 2QJZA 2WE6A 2VZGB 3KY9A 1TJTA 1VKAA 1MB8A 2WA5A 1QAGA 1WYRA 2K3SA 5FMTA 5A37A 2E9KA 1PXYA 1BHDA 2K2RA 1WYQA 2D85A 1P2XA 4TXIA 1BKRA 5J8EA 3HOCA 2EYIA 1EUVA 2HKPA 3VP7A 4Q59A 3F7PA 5FMUA 4EDNA 4LVRA 4DDPA 1WYLA 2R8UA 2D88A 1H67A 1WKUA 5A38A 4Q57B 1V5KA 1DXXA 5BVRA 3EAYA 2RR8A 2HL9A 3FERA 2QJXA 2EQOA 1UJOA 3HOPA 1WYPA 1RT8A 2WDTA 4EDMA 4LVPA 1AA2A 3CO1A 2R0OA 2WFNA 1SH5A 3JAKM 2VZDA 1WYOA 2D87A 1P5SA 5A4BA 2EE7A 2VE7A 2EYNA 4Q58A 5A36A 3KMWB 2WA7A 2L3GA 2YRNA 2D86A 2DK9A 1UEGA 2HL8A 3HORA 2VZIB 5L0OA 1AOAA 3JARM
chains in the Genus database with same CATH topology
2VZCA 3KMUB 4B7LA 2JV9A 2D89A 3JALM 4TXKA 2WA6A 1WYNA 3I6XA 1WJOA 1WIXA 1SH6A 1WYMA 3REPB 4EDLA 1PA7A 2QJZA 2VZGB 3KY9A 1TJTA 1VKAA 1MB8A 2WA5A 1QAGA 1WYRA 2K3SA 5A37A 2E9KA 1PXYA 1BHDA 2K2RA 1WYQA 2D85A 1P2XA 4TXIA 1BKRA 5J8EA 3HOCA 2EYIA 4Q59A 3F7PA 4EDNA 1WYLA 2R8UA 2D88A 1H67A 1WKUA 5A38A 4Q57B 1V5KA 1DXXA 5BVRA 2RR8A 3FERA 2QJXA 1UJOA 3HOPA 1WYPA 1RT8A 4EDMA 1AA2A 3CO1A 2R0OA 2WFNA 1SH5A 3JAKM 2VZDA 1WYOA 2D87A 1P5SA 5A4BA 2EE7A 2EYNA 4Q58A 5A36A 3KMWB 2WA7A 2L3GA 2YRNA 2D86A 2DK9A 1UEGA 3HORA 2VZIB 5L0OA 1AOAA 3JARM
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VZC A;  3KMU B;  4B7L A;  2JV9 A;  2D89 A;  3JAL M;  4TXK A;  2WA6 A;  1WYN A;  3I6X A;  1WJO A;  1WIX A;  1SH6 A;  1WYM A;  3REP B;  4EDL A;  1PA7 A;  2QJZ A;  2VZG B;  3KY9 A;  1TJT A;  1VKA A;  1MB8 A;  2WA5 A;  1QAG A;  1WYR A;  2K3S A;  5A37 A;  2E9K A;  1PXY A;  1BHD A;  2K2R A;  1WYQ A;  2D85 A;  1P2X A;  4TXI A;  1BKR A;  5J8E A;  3HOC A;  2EYI A;  4Q59 A;  3F7P A;  4EDN A;  1WYL A;  2R8U A;  2D88 A;  1H67 A;  1WKU A;  5A38 A;  4Q57 B;  1V5K A;  1DXX A;  5BVR A;  2RR8 A;  3FER A;  2QJX A;  1UJO A;  3HOP A;  1WYP A;  1RT8 A;  4EDM A;  1AA2 A;  3CO1 A;  2R0O A;  2WFN A;  1SH5 A;  3JAK M;  2VZD A;  1WYO A;  2D87 A;  1P5S A;  5A4B A;  2EE7 A;  2EYN A;  4Q58 A;  5A36 A;  3KMW B;  2WA7 A;  2L3G A;  2YRN A;  2D86 A;  2DK9 A;  1UEG A;  3HOR A;  2VZI B;  5L0O A;  1AOA A;  3JAR M; 
#chains in the Genus database with same CATH topology
 2VZC A;  2IGP A;  2VE7 C;  3KMU B;  4B7L A;  2JV9 A;  2D89 A;  3JAL M;  4TXK A;  2WA6 A;  1WYN A;  3I6X A;  1WJO A;  1WIX A;  1SH6 A;  1WYM A;  3REP B;  4EDL A;  1PA7 A;  2QJZ A;  2WE6 A;  2VZG B;  3KY9 A;  1TJT A;  1VKA A;  1MB8 A;  2WA5 A;  1QAG A;  1WYR A;  2K3S A;  5FMT A;  5A37 A;  2E9K A;  1PXY A;  1BHD A;  2K2R A;  1WYQ A;  2D85 A;  1P2X A;  4TXI A;  1BKR A;  5J8E A;  3HOC A;  2EYI A;  1EUV A;  2HKP A;  3VP7 A;  4Q59 A;  3F7P A;  5FMU A;  4EDN A;  4LVR A;  4DDP A;  1WYL A;  2R8U A;  2D88 A;  1H67 A;  1WKU A;  5A38 A;  4Q57 B;  1V5K A;  1DXX A;  5BVR A;  3EAY A;  2RR8 A;  2HL9 A;  3FER A;  2QJX A;  2EQO A;  1UJO A;  3HOP A;  1WYP A;  1RT8 A;  2WDT A;  4EDM A;  4LVP A;  1AA2 A;  3CO1 A;  2R0O A;  2WFN A;  1SH5 A;  3JAK M;  2VZD A;  1WYO A;  2D87 A;  1P5S A;  5A4B A;  2EE7 A;  2VE7 A;  2EYN A;  4Q58 A;  5A36 A;  3KMW B;  2WA7 A;  2L3G A;  2YRN A;  2D86 A;  2DK9 A;  1UEG A;  2HL8 A;  3HOR A;  2VZI B;  5L0O A;  1AOA A;  3JAR M; 
#chains in the Genus database with same CATH homology
 2VZC A;  3KMU B;  4B7L A;  2JV9 A;  2D89 A;  3JAL M;  4TXK A;  2WA6 A;  1WYN A;  3I6X A;  1WJO A;  1WIX A;  1SH6 A;  1WYM A;  3REP B;  4EDL A;  1PA7 A;  2QJZ A;  2VZG B;  3KY9 A;  1TJT A;  1VKA A;  1MB8 A;  2WA5 A;  1QAG A;  1WYR A;  2K3S A;  5A37 A;  2E9K A;  1PXY A;  1BHD A;  2K2R A;  1WYQ A;  2D85 A;  1P2X A;  4TXI A;  1BKR A;  5J8E A;  3HOC A;  2EYI A;  4Q59 A;  3F7P A;  4EDN A;  1WYL A;  2R8U A;  2D88 A;  1H67 A;  1WKU A;  5A38 A;  4Q57 B;  1V5K A;  1DXX A;  5BVR A;  2RR8 A;  3FER A;  2QJX A;  1UJO A;  3HOP A;  1WYP A;  1RT8 A;  4EDM A;  1AA2 A;  3CO1 A;  2R0O A;  2WFN A;  1SH5 A;  3JAK M;  2VZD A;  1WYO A;  2D87 A;  1P5S A;  5A4B A;  2EE7 A;  2EYN A;  4Q58 A;  5A36 A;  3KMW B;  2WA7 A;  2L3G A;  2YRN A;  2D86 A;  2DK9 A;  1UEG A;  3HOR A;  2VZI B;  5L0O A;  1AOA A;  3JAR M; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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