1TJT | Genus

Total Genus 82

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	82
sequence length	224
structure length	224
Chain Sequence	AWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPRPDKGKMRFHKIANVNKALDFIASKGVKLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNVQNFHTSWKDGLALCALIHRHRPDLIDYAKLRKDDPIGNLNTAFEVAEKYLDIPKMLDAEDIVNTPKPDEKAIMTYVSCFYHAFAG

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

loadScript /static/js/j2s/core/package.js

loadScript /static/js/j2s/core/corejmol.z.js

loadScript /static/js/j2s/core/corescript.z.js

JSmol exec jmolApplet0 start applet null

Jmol JavaScript applet jmolApplet0__346973844621413__ initializing

Jmol getValue debug null

Jmol getValue logLevel null

Jmol getValue allowjavascript null

AppletRegistry.checkIn(jmolApplet0__346973844621413__)

vwrOptions:

{ "name":"jmolApplet0","applet":true,"documentBase":"https://genus.fuw.edu.pl/view/1TJT/A/","platform":"J.awtjs2d.Platform","fullName":"jmolApplet0__346973844621413__","codePath":"https:/static/js/j2s/","display":"jmolApplet0_canvas2d","signedApplet":"true","appletReadyCallback":"Jmol._readyCallback","statusListener":"[J.appletjs.Jmol object]","syncId":"346973844621413","bgcolor":"white" }

setting document base to "https://genus.fuw.edu.pl/view/1TJT/A/"

Jmol Version: 14.29.13 2018-04-17 17:17

java.vendor: Java2Script (HTML5)

java.version: 2018-01-28 23:38:52 (JSmol/j2s)

os.name: Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)

Access: ALL

memory: 0.0/0.0

processors available: 1

useCommandThread: false

appletId:jmolApplet0 (signed)

Jmol getValue emulate null

defaults = "Jmol"

Jmol getValue boxbgcolor null

Jmol getValue bgcolor white

backgroundColor = "white"

Jmol getValue ANIMFRAMECallback null

Jmol getValue APPLETREADYCallback Jmol._readyCallback

APPLETREADYCallback = "Jmol._readyCallback"

callback set for APPLETREADYCallback Jmol._readyCallback APPLETREADY

Jmol getValue ATOMMOVEDCallback null

Jmol getValue AUDIOCallback null

Jmol getValue CLICKCallback null

Jmol getValue DRAGDROPCallback null

Jmol getValue ECHOCallback null

Jmol getValue ERRORCallback null

Jmol getValue EVALCallback null

Jmol getValue HOVERCallback null

Jmol getValue IMAGECallback null

Jmol getValue LOADSTRUCTCallback null

Jmol getValue MEASURECallback null

Jmol getValue MESSAGECallback null

Jmol getValue MINIMIZATIONCallback null

Jmol getValue SERVICECallback null

Jmol getValue PICKCallback null

Jmol getValue RESIZECallback null

Jmol getValue SCRIPTCallback null

Jmol getValue SYNCCallback null

Jmol getValue STRUCTUREMODIFIEDCallback null

Jmol getValue doTranslate null

language=en_US

Jmol getValue popupMenu null

Jmol getValue script null

Jmol getValue loadInline null

Jmol getValue load null

Jmol applet jmolApplet0__346973844621413__ ready

script 1 started

platformSpeed = 8

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Contractile protein
source organism	Homo sapiens
publication title	The crystal structure of the actin binding domain from alpha-actinin in its closed conformation: structural insight into phospholipid regulation of alpha-actinin pubmed doi rcsb
molecule keywords	Alpha-actinin 3
total genus	82
structure length	224
sequence length	224
ec nomenclature
pdb deposition date	2004-06-07

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00307	CH	Calponin homology (CH) domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.418.10	Mainly Alpha	Orthogonal Bundle	Actin-binding Protein, T-fimbrin; domain 1	Calponin-like domain	1tjtA02
1.10.418.10	Mainly Alpha	Orthogonal Bundle	Actin-binding Protein, T-fimbrin; domain 1	Calponin-like domain	1tjtA01

2QJXA 1WJOA 1MB8A 2WFNA 3HOPA 2VZIB 1BHDA 4EDMA 1SH6A 1H67A 4Q58A 1V5KA 2YRNA 1RT8A 2D89A 1PXYA 1WYOA 2RR8A 1AA2A 1WYLA 5BVRA 1WYNA 2D85A 3REPB 5L0OA 2WA5A 2EYIA 4TXIA 5J8EA 1BKRA 3JALM 1DXXA 5A36A 1WIXA 3KMUB 1P5SA 3HORA 2E9KA 2EE7A 4Q59A 2R0OA 1SH5A 4Q57B 1TJTA 3HOCA 1WYPA 3JAKM 3FERA 2L3GA 5A38A 1QAGA 1WYRA 2K2RA 3CO1A 2K3SA 4EDLA 5A37A 2JV9A 1WYQA 1VKAA 2R8UA 2QJZA 1AOAA 1WKUA 2D87A 1UEGA 3I6XA 3KMWB 1P2XA 2D86A 2D88A 1PA7A 2VZCA 2DK9A 2VZGB 3F7PA 1UJOA 4TXKA 2WA6A 5A4BA 2VZDA 3KY9A 2WA7A 4EDNA 4B7LA 3JARM 1WYMA 2EYNA
chains in the Genus database with same CATH superfamily

2QJXA 2HL8A 1WJOA 1MB8A 2WFNA 3HOPA 2WE6A 2VZIB 1BHDA 4EDMA 1SH6A 1H67A 4Q58A 1V5KA 2YRNA 1RT8A 2D89A 1PXYA 2HL9A 1EUVA 4DDPA 1WYOA 2RR8A 4LVPA 1AA2A 2WDTA 1WYLA 5BVRA 1WYNA 2D85A 3REPB 5L0OA 2WA5A 2EYIA 3VP7A 4TXIA 5J8EA 1BKRA 3JALM 1DXXA 5A36A 1WIXA 3KMUB 1P5SA 3HORA 2E9KA 2EE7A 4Q59A 2R0OA 1SH5A 2IGPA 4Q57B 1TJTA 3HOCA 1WYPA 3JAKM 3FERA 2L3GA 1WYMA 5A38A 1QAGA 1WYRA 2K2RA 3CO1A 2EQOA 2K3SA 4EDLA 5A37A 4LVRA 2JV9A 1WYQA 1VKAA 2R8UA 2QJZA 1AOAA 1WKUA 2D87A 1UEGA 2VE7C 3I6XA 3KMWB 1P2XA 2D86A 5FMTA 2D88A 1PA7A 2VZCA 2DK9A 2VZGB 2VE7A 3F7PA 1UJOA 4TXKA 2WA6A 5A4BA 2VZDA 3KY9A 5FMUA 2WA7A 4EDNA 4B7LA 3JARM 3EAYA 2HKPA 2EYNA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2QJX A;  1WJO A;  1MB8 A;  2WFN A;  3HOP A;  2VZI B;  1BHD A;  4EDM A;  1SH6 A;  1H67 A;  4Q58 A;  1V5K A;  2YRN A;  1RT8 A;  2D89 A;  1PXY A;  1WYO A;  2RR8 A;  1AA2 A;  1WYL A;  5BVR A;  1WYN A;  2D85 A;  3REP B;  5L0O A;  2WA5 A;  2EYI A;  4TXI A;  5J8E A;  1BKR A;  3JAL M;  1DXX A;  5A36 A;  1WIX A;  3KMU B;  1P5S A;  3HOR A;  2E9K A;  2EE7 A;  4Q59 A;  2R0O A;  1SH5 A;  4Q57 B;  1TJT A;  3HOC A;  1WYP A;  3JAK M;  3FER A;  2L3G A;  5A38 A;  1QAG A;  1WYR A;  2K2R A;  3CO1 A;  2K3S A;  4EDL A;  5A37 A;  2JV9 A;  1WYQ A;  1VKA A;  2R8U A;  2QJZ A;  1AOA A;  1WKU A;  2D87 A;  1UEG A;  3I6X A;  3KMW B;  1P2X A;  2D86 A;  2D88 A;  1PA7 A;  2VZC A;  2DK9 A;  2VZG B;  3F7P A;  1UJO A;  4TXK A;  2WA6 A;  5A4B A;  2VZD A;  3KY9 A;  2WA7 A;  4EDN A;  4B7L A;  3JAR M;  1WYM A;  2EYN A; 
#chains in the Genus database with same CATH topology
 2QJX A;  2HL8 A;  1WJO A;  1MB8 A;  2WFN A;  3HOP A;  2WE6 A;  2VZI B;  1BHD A;  4EDM A;  1SH6 A;  1H67 A;  4Q58 A;  1V5K A;  2YRN A;  1RT8 A;  2D89 A;  1PXY A;  2HL9 A;  1EUV A;  4DDP A;  1WYO A;  2RR8 A;  4LVP A;  1AA2 A;  2WDT A;  1WYL A;  5BVR A;  1WYN A;  2D85 A;  3REP B;  5L0O A;  2WA5 A;  2EYI A;  3VP7 A;  4TXI A;  5J8E A;  1BKR A;  3JAL M;  1DXX A;  5A36 A;  1WIX A;  3KMU B;  1P5S A;  3HOR A;  2E9K A;  2EE7 A;  4Q59 A;  2R0O A;  1SH5 A;  2IGP A;  4Q57 B;  1TJT A;  3HOC A;  1WYP A;  3JAK M;  3FER A;  2L3G A;  1WYM A;  5A38 A;  1QAG A;  1WYR A;  2K2R A;  3CO1 A;  2EQO A;  2K3S A;  4EDL A;  5A37 A;  4LVR A;  2JV9 A;  1WYQ A;  1VKA A;  2R8U A;  2QJZ A;  1AOA A;  1WKU A;  2D87 A;  1UEG A;  2VE7 C;  3I6X A;  3KMW B;  1P2X A;  2D86 A;  5FMT A;  2D88 A;  1PA7 A;  2VZC A;  2DK9 A;  2VZG B;  2VE7 A;  3F7P A;  1UJO A;  4TXK A;  2WA6 A;  5A4B A;  2VZD A;  3KY9 A;  5FMU A;  2WA7 A;  4EDN A;  4B7L A;  3JAR M;  3EAY A;  2HKP A;  2EYN A; 
#chains in the Genus database with same CATH homology
 2QJX A;  1WJO A;  1MB8 A;  2WFN A;  3HOP A;  2VZI B;  1BHD A;  4EDM A;  1SH6 A;  1H67 A;  4Q58 A;  1V5K A;  2YRN A;  1RT8 A;  2D89 A;  1PXY A;  1WYO A;  2RR8 A;  1AA2 A;  1WYL A;  5BVR A;  1WYN A;  2D85 A;  3REP B;  5L0O A;  2WA5 A;  2EYI A;  4TXI A;  5J8E A;  1BKR A;  3JAL M;  1DXX A;  5A36 A;  1WIX A;  3KMU B;  1P5S A;  3HOR A;  2E9K A;  2EE7 A;  4Q59 A;  2R0O A;  1SH5 A;  4Q57 B;  1TJT A;  3HOC A;  1WYP A;  3JAK M;  3FER A;  2L3G A;  5A38 A;  1QAG A;  1WYR A;  2K2R A;  3CO1 A;  2K3S A;  4EDL A;  5A37 A;  2JV9 A;  1WYQ A;  1VKA A;  2R8U A;  2QJZ A;  1AOA A;  1WKU A;  2D87 A;  1UEG A;  3I6X A;  3KMW B;  1P2X A;  2D86 A;  2D88 A;  1PA7 A;  2VZC A;  2DK9 A;  2VZG B;  3F7P A;  1UJO A;  4TXK A;  2WA6 A;  5A4B A;  2VZD A;  3KY9 A;  2WA7 A;  4EDN A;  4B7L A;  3JAR M;  1WYM A;  2EYN A;

...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)

...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...

1TJTA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations