2A78B

Crystal structure of the c3bot-rala complex reveals a novel type of action of a bacterial exoenzyme
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
207
structure length
207
Chain Sequence
TYQEFTNIDQAKAWGNAQYKKYGLSKSEKEAIVSYTKSASEINGKLRQNKGVINGFPSNLIKQVELLDKSFNKMKTPENIMLFRGDDPAYLGTEFQNTLLNSNGTINKTAFEKAKAKFLNKDRLEYGYISTSLMNVSQFAGRPIITKFKVAKGSKAGYIDPISAFAGQLEMLLPRHSTYHIDDMRLSSDGKQIIITATMMGTAINPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the C3bot-RalA complex reveals a novel type of action of a bacterial exoenzyme.
pubmed doi rcsb
molecule tags Protein binding/transferase
source organism Homo sapiens
molecule keywords Ras-related protein Ral-A
total genus 70
structure length 207
sequence length 207
ec nomenclature ec 2.4.2.-:
pdb deposition date 2005-07-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2a78B00
2GWLA 1YQYA 4FK7A 4WF6A 4GF1A 1PWUA 4ELNA 1G24A 2A9KB 5BWMB 2WN7A 1PWWA 5GTTA 2C8CA 1OJQA 1PWPA 2C8EE 4DV8A 5H04A 1QS1A 1R45A 4XSHB 1PWQA 4XM8A 4PKTA 3BW8A 1OG4A 1GIQA 1OG3A 2WN6A 4H03A 4GY2A 4H0VA 1GXYA 2C8AA 4PKUA 2WN4A 1J7NA 2J3VA 2C8GA 4XM7A 4TR5A 1UZIA 4XM6A 1GZFA 4PKVA 3U0JA 1PWVA 4H0XA 1OG1A 2A78B 1OJZA 1GY0A 2C8FE 2WN8A 1GIRA 3NTSA 2BOVB 5D1SA 1JKYA 1GZEA 2C8HA 1R4BA 3BUZA 2GWMA 4FXQA 1GXZA 2C8BX 4H0TA 2C89A 5D1TA 4FMLA 2J3ZA 4PKSA 4H0YA 2J3XA 4XSGB 5DZQA 5H03A 4PKQA 2C8DA 2WN5A 1ZXVA 5D1UA 1QS2A 4PKRA 4PKWA
chains in the Genus database with same CATH superfamily
2GWLA 1YQYA 4FK7A 4WF6A 4GF1A 1PWUA 4ELNA 1G24A 2A9KB 5BWMB 2WN7A 1PWWA 5GTTA 2C8CA 1OJQA 1PWPA 2C8EE 4DV8A 5H04A 1QS1A 1R45A 4XSHB 1PWQA 4XM8A 4PKTA 3BW8A 1OG4A 1GIQA 1OG3A 2WN6A 4H03A 4GY2A 4H0VA 1GXYA 2C8AA 4PKUA 2WN4A 1J7NA 2J3VA 2C8GA 4XM7A 4TR5A 1UZIA 4XM6A 1GZFA 4PKVA 3U0JA 1PWVA 4H0XA 1OG1A 2A78B 1OJZA 1GY0A 2C8FE 2WN8A 1GIRA 3NTSA 2BOVB 5D1SA 1JKYA 1GZEA 2C8HA 1R4BA 3BUZA 2GWMA 4FXQA 1GXZA 2C8BX 4H0TA 2C89A 5D1TA 4FMLA 2J3ZA 4PKSA 4H0YA 2J3XA 4XSGB 5DZQA 5H03A 4PKQA 2C8DA 2WN5A 1ZXVA 5D1UA 1QS2A 4PKRA 4PKWA
chains in the Genus database with same CATH topology
2GWLA 1YQYA 4FK7A 4WF6A 4GF1A 1PWUA 4ELNA 1G24A 2A9KB 5BWMB 2WN7A 1PWWA 5GTTA 2C8CA 1OJQA 1PWPA 2C8EE 4DV8A 5H04A 1QS1A 1R45A 4XSHB 1PWQA 4XM8A 4PKTA 3BW8A 1OG4A 1GIQA 1OG3A 2WN6A 4H03A 4GY2A 4H0VA 1GXYA 2C8AA 4PKUA 2WN4A 1J7NA 2J3VA 2C8GA 4XM7A 4TR5A 1UZIA 4XM6A 1GZFA 4PKVA 3U0JA 1PWVA 4H0XA 1OG1A 2A78B 1OJZA 1GY0A 2C8FE 2WN8A 1GIRA 3NTSA 2BOVB 5D1SA 1JKYA 1GZEA 2C8HA 1R4BA 3BUZA 2GWMA 4FXQA 1GXZA 2C8BX 4H0TA 2C89A 5D1TA 4FMLA 2J3ZA 4PKSA 4H0YA 2J3XA 4XSGB 5DZQA 5H03A 4PKQA 2C8DA 2WN5A 1ZXVA 5D1UA 1QS2A 4PKRA 4PKWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GWL A;  1YQY A;  4FK7 A;  4WF6 A;  4GF1 A;  1PWU A;  4ELN A;  1G24 A;  2A9K B;  5BWM B;  2WN7 A;  1PWW A;  5GTT A;  2C8C A;  1OJQ A;  1PWP A;  2C8E E;  4DV8 A;  5H04 A;  1QS1 A;  1R45 A;  4XSH B;  1PWQ A;  4XM8 A;  4PKT A;  3BW8 A;  1OG4 A;  1GIQ A;  1OG3 A;  2WN6 A;  4H03 A;  4GY2 A;  4H0V A;  1GXY A;  2C8A A;  4PKU A;  2WN4 A;  1J7N A;  2J3V A;  2C8G A;  4XM7 A;  4TR5 A;  1UZI A;  4XM6 A;  1GZF A;  4PKV A;  3U0J A;  1PWV A;  4H0X A;  1OG1 A;  2A78 B;  1OJZ A;  1GY0 A;  2C8F E;  2WN8 A;  1GIR A;  3NTS A;  2BOV B;  5D1S A;  1JKY A;  1GZE A;  2C8H A;  1R4B A;  3BUZ A;  2GWM A;  4FXQ A;  1GXZ A;  2C8B X;  4H0T A;  2C89 A;  5D1T A;  4FML A;  2J3Z A;  4PKS A;  4H0Y A;  2J3X A;  4XSG B;  5DZQ A;  5H03 A;  4PKQ A;  2C8D A;  2WN5 A;  1ZXV A;  5D1U A;  1QS2 A;  4PKR A;  4PKW A; 
#chains in the Genus database with same CATH topology
 2GWL A;  1YQY A;  4FK7 A;  4WF6 A;  4GF1 A;  1PWU A;  4ELN A;  1G24 A;  2A9K B;  5BWM B;  2WN7 A;  1PWW A;  5GTT A;  2C8C A;  1OJQ A;  1PWP A;  2C8E E;  4DV8 A;  5H04 A;  1QS1 A;  1R45 A;  4XSH B;  1PWQ A;  4XM8 A;  4PKT A;  3BW8 A;  1OG4 A;  1GIQ A;  1OG3 A;  2WN6 A;  4H03 A;  4GY2 A;  4H0V A;  1GXY A;  2C8A A;  4PKU A;  2WN4 A;  1J7N A;  2J3V A;  2C8G A;  4XM7 A;  4TR5 A;  1UZI A;  4XM6 A;  1GZF A;  4PKV A;  3U0J A;  1PWV A;  4H0X A;  1OG1 A;  2A78 B;  1OJZ A;  1GY0 A;  2C8F E;  2WN8 A;  1GIR A;  3NTS A;  2BOV B;  5D1S A;  1JKY A;  1GZE A;  2C8H A;  1R4B A;  3BUZ A;  2GWM A;  4FXQ A;  1GXZ A;  2C8B X;  4H0T A;  2C89 A;  5D1T A;  4FML A;  2J3Z A;  4PKS A;  4H0Y A;  2J3X A;  4XSG B;  5DZQ A;  5H03 A;  4PKQ A;  2C8D A;  2WN5 A;  1ZXV A;  5D1U A;  1QS2 A;  4PKR A;  4PKW A; 
#chains in the Genus database with same CATH homology
 2GWL A;  1YQY A;  4FK7 A;  4WF6 A;  4GF1 A;  1PWU A;  4ELN A;  1G24 A;  2A9K B;  5BWM B;  2WN7 A;  1PWW A;  5GTT A;  2C8C A;  1OJQ A;  1PWP A;  2C8E E;  4DV8 A;  5H04 A;  1QS1 A;  1R45 A;  4XSH B;  1PWQ A;  4XM8 A;  4PKT A;  3BW8 A;  1OG4 A;  1GIQ A;  1OG3 A;  2WN6 A;  4H03 A;  4GY2 A;  4H0V A;  1GXY A;  2C8A A;  4PKU A;  2WN4 A;  1J7N A;  2J3V A;  2C8G A;  4XM7 A;  4TR5 A;  1UZI A;  4XM6 A;  1GZF A;  4PKV A;  3U0J A;  1PWV A;  4H0X A;  1OG1 A;  2A78 B;  1OJZ A;  1GY0 A;  2C8F E;  2WN8 A;  1GIR A;  3NTS A;  2BOV B;  5D1S A;  1JKY A;  1GZE A;  2C8H A;  1R4B A;  3BUZ A;  2GWM A;  4FXQ A;  1GXZ A;  2C8B X;  4H0T A;  2C89 A;  5D1T A;  4FML A;  2J3Z A;  4PKS A;  4H0Y A;  2J3X A;  4XSG B;  5DZQ A;  5H03 A;  4PKQ A;  2C8D A;  2WN5 A;  1ZXV A;  5D1U A;  1QS2 A;  4PKR A;  4PKW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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