2A78B

Crystal structure of the c3bot-rala complex reveals a novel type of action of a bacterial exoenzyme
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
207
structure length
207
Chain Sequence
TYQEFTNIDQAKAWGNAQYKKYGLSKSEKEAIVSYTKSASEINGKLRQNKGVINGFPSNLIKQVELLDKSFNKMKTPENIMLFRGDDPAYLGTEFQNTLLNSNGTINKTAFEKAKAKFLNKDRLEYGYISTSLMNVSQFAGRPIITKFKVAKGSKAGYIDPISAFAGQLEMLLPRHSTYHIDDMRLSSDGKQIIITATMMGTAINPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the C3bot-RalA complex reveals a novel type of action of a bacterial exoenzyme.
pubmed doi rcsb
molecule tags Protein binding/transferase
source organism Homo sapiens
molecule keywords Ras-related protein Ral-A
total genus 70
structure length 207
sequence length 207
ec nomenclature ec 2.4.2.-:
pdb deposition date 2005-07-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2a78B00
2WN7A 4TR5A 2A9KB 4XSGB 1GZFA 4PKRA 2BOVB 4FXQA 2C8HA 1QS2A 2C8DA 4XM8A 2GWLA 1R45A 4H0XA 1PWWA 4H03A 3U0JA 1YQYA 2WN6A 2C8CA 1GY0A 1G24A 3BW8A 4XM7A 1PWPA 4PKQA 4H0TA 4PKWA 1GXYA 2GWMA 5D1SA 4XM6A 1GZEA 2C8FE 5D1TA 1R4BA 2J3ZA 4FMLA 4FK7A 1PWUA 4PKUA 4WF6A 5DZQA 1UZIA 4GF1A 2J3XA 2A78B 1PWVA 2WN8A 2C89A 4H0YA 5H04A 2WN5A 2C8BX 2C8GA 2J3VA 4DV8A 5BWMB 1GIQA 3BUZA 5H03A 3NTSA 4PKVA 4XSHB 2WN4A 5GTTA 1GXZA 4PKTA 1OG4A 4H0VA 1ZXVA 4ELNA 2C8AA 1QS1A 1OJZA 5D1UA 4GY2A 1OG1A 2C8EE 1J7NA 1JKYA 1OJQA 4PKSA 1OG3A 1GIRA 1PWQA
chains in the Genus database with same CATH superfamily
2WN7A 4TR5A 2A9KB 4XSGB 1GZFA 4PKRA 2BOVB 4FXQA 2C8HA 1QS2A 2C8DA 4XM8A 2GWLA 1R45A 4H0XA 1PWWA 4H03A 3U0JA 1YQYA 2WN6A 2C8CA 1GY0A 1G24A 3BW8A 4XM7A 1PWPA 4PKQA 4H0TA 4PKWA 1GXYA 2GWMA 5D1SA 4XM6A 1GZEA 2C8FE 5D1TA 1R4BA 2J3ZA 4FMLA 4FK7A 1PWUA 4PKUA 4WF6A 5DZQA 1UZIA 4GF1A 2J3XA 2A78B 1PWVA 2WN8A 2C89A 4H0YA 5H04A 2WN5A 2C8BX 2C8GA 2J3VA 4DV8A 5BWMB 1GIQA 3BUZA 5H03A 3NTSA 4PKVA 4XSHB 2WN4A 5GTTA 1GXZA 4PKTA 1OG4A 4H0VA 1ZXVA 4ELNA 2C8AA 1QS1A 1OJZA 5D1UA 4GY2A 1OG1A 2C8EE 1J7NA 1JKYA 1OJQA 4PKSA 1OG3A 1GIRA 1PWQA
chains in the Genus database with same CATH topology
2WN7A 4TR5A 2A9KB 4XSGB 1GZFA 4PKRA 2BOVB 4FXQA 2C8HA 1QS2A 2C8DA 4XM8A 2GWLA 1R45A 4H0XA 1PWWA 4H03A 3U0JA 1YQYA 2WN6A 2C8CA 1GY0A 1G24A 3BW8A 4XM7A 1PWPA 4PKQA 4H0TA 4PKWA 1GXYA 2GWMA 5D1SA 4XM6A 1GZEA 2C8FE 5D1TA 1R4BA 2J3ZA 4FMLA 4FK7A 1PWUA 4PKUA 4WF6A 5DZQA 1UZIA 4GF1A 2J3XA 2A78B 1PWVA 2WN8A 2C89A 4H0YA 5H04A 2WN5A 2C8BX 2C8GA 2J3VA 4DV8A 5BWMB 1GIQA 3BUZA 5H03A 3NTSA 4PKVA 4XSHB 2WN4A 5GTTA 1GXZA 4PKTA 1OG4A 4H0VA 1ZXVA 4ELNA 2C8AA 1QS1A 1OJZA 5D1UA 4GY2A 1OG1A 2C8EE 1J7NA 1JKYA 1OJQA 4PKSA 1OG3A 1GIRA 1PWQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WN7 A;  4TR5 A;  2A9K B;  4XSG B;  1GZF A;  4PKR A;  2BOV B;  4FXQ A;  2C8H A;  1QS2 A;  2C8D A;  4XM8 A;  2GWL A;  1R45 A;  4H0X A;  1PWW A;  4H03 A;  3U0J A;  1YQY A;  2WN6 A;  2C8C A;  1GY0 A;  1G24 A;  3BW8 A;  4XM7 A;  1PWP A;  4PKQ A;  4H0T A;  4PKW A;  1GXY A;  2GWM A;  5D1S A;  4XM6 A;  1GZE A;  2C8F E;  5D1T A;  1R4B A;  2J3Z A;  4FML A;  4FK7 A;  1PWU A;  4PKU A;  4WF6 A;  5DZQ A;  1UZI A;  4GF1 A;  2J3X A;  2A78 B;  1PWV A;  2WN8 A;  2C89 A;  4H0Y A;  5H04 A;  2WN5 A;  2C8B X;  2C8G A;  2J3V A;  4DV8 A;  5BWM B;  1GIQ A;  3BUZ A;  5H03 A;  3NTS A;  4PKV A;  4XSH B;  2WN4 A;  5GTT A;  1GXZ A;  4PKT A;  1OG4 A;  4H0V A;  1ZXV A;  4ELN A;  2C8A A;  1QS1 A;  1OJZ A;  5D1U A;  4GY2 A;  1OG1 A;  2C8E E;  1J7N A;  1JKY A;  1OJQ A;  4PKS A;  1OG3 A;  1GIR A;  1PWQ A; 
#chains in the Genus database with same CATH topology
 2WN7 A;  4TR5 A;  2A9K B;  4XSG B;  1GZF A;  4PKR A;  2BOV B;  4FXQ A;  2C8H A;  1QS2 A;  2C8D A;  4XM8 A;  2GWL A;  1R45 A;  4H0X A;  1PWW A;  4H03 A;  3U0J A;  1YQY A;  2WN6 A;  2C8C A;  1GY0 A;  1G24 A;  3BW8 A;  4XM7 A;  1PWP A;  4PKQ A;  4H0T A;  4PKW A;  1GXY A;  2GWM A;  5D1S A;  4XM6 A;  1GZE A;  2C8F E;  5D1T A;  1R4B A;  2J3Z A;  4FML A;  4FK7 A;  1PWU A;  4PKU A;  4WF6 A;  5DZQ A;  1UZI A;  4GF1 A;  2J3X A;  2A78 B;  1PWV A;  2WN8 A;  2C89 A;  4H0Y A;  5H04 A;  2WN5 A;  2C8B X;  2C8G A;  2J3V A;  4DV8 A;  5BWM B;  1GIQ A;  3BUZ A;  5H03 A;  3NTS A;  4PKV A;  4XSH B;  2WN4 A;  5GTT A;  1GXZ A;  4PKT A;  1OG4 A;  4H0V A;  1ZXV A;  4ELN A;  2C8A A;  1QS1 A;  1OJZ A;  5D1U A;  4GY2 A;  1OG1 A;  2C8E E;  1J7N A;  1JKY A;  1OJQ A;  4PKS A;  1OG3 A;  1GIR A;  1PWQ A; 
#chains in the Genus database with same CATH homology
 2WN7 A;  4TR5 A;  2A9K B;  4XSG B;  1GZF A;  4PKR A;  2BOV B;  4FXQ A;  2C8H A;  1QS2 A;  2C8D A;  4XM8 A;  2GWL A;  1R45 A;  4H0X A;  1PWW A;  4H03 A;  3U0J A;  1YQY A;  2WN6 A;  2C8C A;  1GY0 A;  1G24 A;  3BW8 A;  4XM7 A;  1PWP A;  4PKQ A;  4H0T A;  4PKW A;  1GXY A;  2GWM A;  5D1S A;  4XM6 A;  1GZE A;  2C8F E;  5D1T A;  1R4B A;  2J3Z A;  4FML A;  4FK7 A;  1PWU A;  4PKU A;  4WF6 A;  5DZQ A;  1UZI A;  4GF1 A;  2J3X A;  2A78 B;  1PWV A;  2WN8 A;  2C89 A;  4H0Y A;  5H04 A;  2WN5 A;  2C8B X;  2C8G A;  2J3V A;  4DV8 A;  5BWM B;  1GIQ A;  3BUZ A;  5H03 A;  3NTS A;  4PKV A;  4XSH B;  2WN4 A;  5GTT A;  1GXZ A;  4PKT A;  1OG4 A;  4H0V A;  1ZXV A;  4ELN A;  2C8A A;  1QS1 A;  1OJZ A;  5D1U A;  4GY2 A;  1OG1 A;  2C8E E;  1J7N A;  1JKY A;  1OJQ A;  4PKS A;  1OG3 A;  1GIR A;  1PWQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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