2C89A

Structure of the wild-type c3bot1 exoenzyme (free state, crystal form i)
Total Genus 64
204060801001201401601802000102030405060
Genus TraceResidueGenus

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
201
structure length
201
Chain Sequence
NTYQEFTNIDQAKAWGNAQYKKYGLSKSEKEAIVSYTKSASEINGKLRQNKGVINGFPSNLIKQVELLDKSFNKMKTPENIMLFRGDDPAYLGTEFQNTLLNSNGTINKTAFEKAKAKFLNKDRLEYGYISTSLMNVSQFAGRPIITKFKVAKGSKAGYIDPISAFAGQLEMLLPRHSTYHIDDMRLSSDGKQIIITATMM
2040608010012014016018020020015010050
0102030405060Genus Matrix

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
EMPTYS3 (165-169)AH1 (52-66)S4 (173-176)AH2 (70-81)3H2 (132-135)AH3 (83-93)TIV1 (140-143)S2 (124-130)TI'1 (93-96)AH4 (102-114)TI1 (97-100)S5 (188-194)S1 (119-120)TIV2 (176-179)3H3 (137-139)TI2 (139-142)TI3 (145-148)S6 (198-199)AH5 (152-162)TII1 (162-165)S7 (201-202)3H4 (181-183)TII2 (195-198)TI4 (183-186)3H1 (115-117)Updating...
connected with : NaN
publication title Structural Basis for the Nad-Hydrolysis Mechanism and the Artt-Loop Plasticity of C3 Exoenzymes.
pubmed doi rcsb
molecule tags Transferase
source organism Clostridium botulinum
molecule keywords MONO-ADP-RIBOSYLTRANSFERASE C3
total genus 64
structure length 201
sequence length 201
chains with identical sequence B, C, D
ec nomenclature ec 2.4.2.-:
pdb deposition date 2005-12-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2c89A00
1GIQA 1GY0A 1PWUA 4PKSA 4H0TA 1GZEA 4H0XA 5GTTA 1YQYA 1PWWA 4FK7A 1OJZA 4FMLA 1QS1A 3U0JA 1R4BA 4PKQA 2C89A 2C8AA 5D1UA 4XM6A 2C8FE 1OG4A 3BUZA 1GZFA 5H03A 4XM7A 4GY2A 4PKWA 2J3ZA 4XSGB 1UZIA 4PKVA 2C8GA 2C8EE 4PKUA 4GF1A 2WN4A 4XM8A 2WN8A 1GIRA 4DV8A 3BW8A 1JKYA 5H04A 2A78B 2C8CA 4H0VA 2WN6A 4PKRA 2WN7A 5BWMB 4XSHB 4FXQA 4H0YA 4ELNA 2C8DA 5D1SA 4H03A 2J3VA 4WF6A 1OG3A 2GWMA 1PWQA 1QS2A 1OG1A 1PWVA 2GWLA 4TR5A 5D1TA 2WN5A 1J7NA 1G24A 2A9KB 4PKTA 2BOVB 2C8HA 1GXYA 1R45A 3NTSA 1OJQA 1ZXVA 1PWPA 1GXZA 2J3XA 5DZQA 2C8BX
chains in the Genus database with same CATH superfamily
1GIQA 1GY0A 1PWUA 4PKSA 4H0TA 1GZEA 4H0XA 5GTTA 1YQYA 1PWWA 4FK7A 1OJZA 4FMLA 1QS1A 3U0JA 1R4BA 4PKQA 2C89A 2C8AA 5D1UA 4XM6A 2C8FE 1OG4A 3BUZA 1GZFA 5H03A 4XM7A 4GY2A 4PKWA 2J3ZA 4XSGB 1UZIA 4PKVA 2C8GA 2C8EE 4PKUA 4GF1A 2WN4A 4XM8A 2WN8A 1GIRA 4DV8A 3BW8A 1JKYA 5H04A 2A78B 2C8CA 4H0VA 2WN6A 4PKRA 2WN7A 5BWMB 4XSHB 4FXQA 4H0YA 4ELNA 2C8DA 5D1SA 4H03A 2J3VA 4WF6A 1OG3A 2GWMA 1PWQA 1QS2A 1OG1A 1PWVA 2GWLA 4TR5A 5D1TA 2WN5A 1J7NA 1G24A 2A9KB 4PKTA 2BOVB 2C8HA 1GXYA 1R45A 3NTSA 1OJQA 1ZXVA 1PWPA 1GXZA 2J3XA 5DZQA 2C8BX
chains in the Genus database with same CATH topology
1GIQA 1GY0A 1PWUA 4PKSA 4H0TA 1GZEA 4H0XA 5GTTA 1YQYA 1PWWA 4FK7A 1OJZA 4FMLA 1QS1A 3U0JA 1R4BA 4PKQA 2C89A 2C8AA 5D1UA 4XM6A 2C8FE 1OG4A 3BUZA 1GZFA 5H03A 4XM7A 4GY2A 4PKWA 2J3ZA 4XSGB 1UZIA 4PKVA 2C8GA 2C8EE 4PKUA 4GF1A 2WN4A 4XM8A 2WN8A 1GIRA 4DV8A 3BW8A 1JKYA 5H04A 2A78B 2C8CA 4H0VA 2WN6A 4PKRA 2WN7A 5BWMB 4XSHB 4FXQA 4H0YA 4ELNA 2C8DA 5D1SA 4H03A 2J3VA 4WF6A 1OG3A 2GWMA 1PWQA 1QS2A 1OG1A 1PWVA 2GWLA 4TR5A 5D1TA 2WN5A 1J7NA 1G24A 2A9KB 4PKTA 2BOVB 2C8HA 1GXYA 1R45A 3NTSA 1OJQA 1ZXVA 1PWPA 1GXZA 2J3XA 5DZQA 2C8BX
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GIQ A;  1GY0 A;  1PWU A;  4PKS A;  4H0T A;  1GZE A;  4H0X A;  5GTT A;  1YQY A;  1PWW A;  4FK7 A;  1OJZ A;  4FML A;  1QS1 A;  3U0J A;  1R4B A;  4PKQ A;  2C89 A;  2C8A A;  5D1U A;  4XM6 A;  2C8F E;  1OG4 A;  3BUZ A;  1GZF A;  5H03 A;  4XM7 A;  4GY2 A;  4PKW A;  2J3Z A;  4XSG B;  1UZI A;  4PKV A;  2C8G A;  2C8E E;  4PKU A;  4GF1 A;  2WN4 A;  4XM8 A;  2WN8 A;  1GIR A;  4DV8 A;  3BW8 A;  1JKY A;  5H04 A;  2A78 B;  2C8C A;  4H0V A;  2WN6 A;  4PKR A;  2WN7 A;  5BWM B;  4XSH B;  4FXQ A;  4H0Y A;  4ELN A;  2C8D A;  5D1S A;  4H03 A;  2J3V A;  4WF6 A;  1OG3 A;  2GWM A;  1PWQ A;  1QS2 A;  1OG1 A;  1PWV A;  2GWL A;  4TR5 A;  5D1T A;  2WN5 A;  1J7N A;  1G24 A;  2A9K B;  4PKT A;  2BOV B;  2C8H A;  1GXY A;  1R45 A;  3NTS A;  1OJQ A;  1ZXV A;  1PWP A;  1GXZ A;  2J3X A;  5DZQ A;  2C8B X; 
#chains in the Genus database with same CATH topology
 1GIQ A;  1GY0 A;  1PWU A;  4PKS A;  4H0T A;  1GZE A;  4H0X A;  5GTT A;  1YQY A;  1PWW A;  4FK7 A;  1OJZ A;  4FML A;  1QS1 A;  3U0J A;  1R4B A;  4PKQ A;  2C89 A;  2C8A A;  5D1U A;  4XM6 A;  2C8F E;  1OG4 A;  3BUZ A;  1GZF A;  5H03 A;  4XM7 A;  4GY2 A;  4PKW A;  2J3Z A;  4XSG B;  1UZI A;  4PKV A;  2C8G A;  2C8E E;  4PKU A;  4GF1 A;  2WN4 A;  4XM8 A;  2WN8 A;  1GIR A;  4DV8 A;  3BW8 A;  1JKY A;  5H04 A;  2A78 B;  2C8C A;  4H0V A;  2WN6 A;  4PKR A;  2WN7 A;  5BWM B;  4XSH B;  4FXQ A;  4H0Y A;  4ELN A;  2C8D A;  5D1S A;  4H03 A;  2J3V A;  4WF6 A;  1OG3 A;  2GWM A;  1PWQ A;  1QS2 A;  1OG1 A;  1PWV A;  2GWL A;  4TR5 A;  5D1T A;  2WN5 A;  1J7N A;  1G24 A;  2A9K B;  4PKT A;  2BOV B;  2C8H A;  1GXY A;  1R45 A;  3NTS A;  1OJQ A;  1ZXV A;  1PWP A;  1GXZ A;  2J3X A;  5DZQ A;  2C8B X; 
#chains in the Genus database with same CATH homology
 1GIQ A;  1GY0 A;  1PWU A;  4PKS A;  4H0T A;  1GZE A;  4H0X A;  5GTT A;  1YQY A;  1PWW A;  4FK7 A;  1OJZ A;  4FML A;  1QS1 A;  3U0J A;  1R4B A;  4PKQ A;  2C89 A;  2C8A A;  5D1U A;  4XM6 A;  2C8F E;  1OG4 A;  3BUZ A;  1GZF A;  5H03 A;  4XM7 A;  4GY2 A;  4PKW A;  2J3Z A;  4XSG B;  1UZI A;  4PKV A;  2C8G A;  2C8E E;  4PKU A;  4GF1 A;  2WN4 A;  4XM8 A;  2WN8 A;  1GIR A;  4DV8 A;  3BW8 A;  1JKY A;  5H04 A;  2A78 B;  2C8C A;  4H0V A;  2WN6 A;  4PKR A;  2WN7 A;  5BWM B;  4XSH B;  4FXQ A;  4H0Y A;  4ELN A;  2C8D A;  5D1S A;  4H03 A;  2J3V A;  4WF6 A;  1OG3 A;  2GWM A;  1PWQ A;  1QS2 A;  1OG1 A;  1PWV A;  2GWL A;  4TR5 A;  5D1T A;  2WN5 A;  1J7N A;  1G24 A;  2A9K B;  4PKT A;  2BOV B;  2C8H A;  1GXY A;  1R45 A;  3NTS A;  1OJQ A;  1ZXV A;  1PWP A;  1GXZ A;  2J3X A;  5DZQ A;  2C8B X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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